1104637-58-2 | 2-Pyridinylboronic acid MIDA ester

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Description

• Catalog Number: AB62995
• Chemical Name: 2-Pyridinylboronic acid MIDA ester
• CAS Number: 1104637-58-2
• Molecular Formula: C10H11BN2O4
• Molecular Weight: 234.0163
• MDL Number: MFCD16621460
• SMILES: O=C1C[N@+]2([B@-](O1)(OC(=O)C2)c1ccccn1)C

Upstream Synthesis Route

2-Pyridinylboronic acid MIDA ester is a versatile compound commonly used in chemical synthesis as a key building block for the construction of various functional molecules. This unique compound is valued for its ability to serve as a highly reactive and stable source of the boronic acid functionality, making it an essential tool for organic chemists.In chemical synthesis, 2-Pyridinylboronic acid MIDA ester is frequently employed in cross-coupling reactions, particularly in Suzuki-Miyaura coupling reactions. This process involves the reaction of the boronic acid moiety with a suitable coupling partner, often an aryl or vinyl halide, under the catalysis of a palladium source. The resulting product is a new carbon-carbon bond formation, allowing for the creation of complex organic structures.Furthermore, the MIDA (methylimidodiacetic acid) ester moiety in 2-Pyridinylboronic acid MIDA ester serves as a protecting group for the boronic acid functionality, enhancing the compound's stability and reactivity in various synthetic transformations. This protection-deprotection strategy enables chemists to selectively manipulate the boronic acid group, facilitating the successful incorporation of this crucial building block into target molecules.Overall, 2-Pyridinylboronic acid MIDA ester plays a vital role in the field of chemical synthesis by enabling the efficient construction of diverse organic compounds through its versatile reactivity and unique properties.