111-24-0 | 1,5-Dibromopentane

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$12.00	$8.00
25g	98%	in stock	$13.00	$9.00
100g	98%	in stock	$26.00	$18.00
500g	98%	in stock	$96.00	$67.00

Description

• Catalog Number: AB43197
• Chemical Name: 1,5-Dibromopentane
• CAS Number: 111-24-0
• Molecular Formula: C5H10Br2
• Molecular Weight: 229.9409
• MDL Number: MFCD00000268
• SMILES: BrCCCCCBr
• NSC Number: 5373

Computed Properties

• Complexity: 25.3
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 7
• Rotatable Bond Count: 4
• XLogP3: 2.8

Upstream Synthesis Route

1,5-Dibromopentane is a valuable compound commonly used in chemical synthesis as a versatile building block. Due to its unique structure containing two bromine atoms on a pentane backbone, this compound exhibits a range of reactivity that makes it highly suitable for various synthetic applications.One key application of 1,5-Dibromopentane is in the synthesis of complex organic molecules. The presence of two reactive bromine atoms allows for selective substitution reactions, making it a useful intermediate in the construction of more elaborate chemical structures. By utilizing 1,5-Dibromopentane as a starting material, chemists can efficiently introduce functional groups and create diverse organic compounds with specific properties.Furthermore, 1,5-Dibromopentane can serve as a precursor for the preparation of biologically active compounds and pharmaceuticals. Its ability to participate in cross-coupling reactions and other transformations enables the formation of intricate molecular frameworks found in many medicinal agents. Through strategic manipulation of the bromine substituents, researchers can access novel chemical entities with potential therapeutic benefits.In summary, the significance of 1,5-Dibromopentane lies in its utility as a synthetic intermediate for constructing complex organic molecules and developing valuable compounds in various fields of chemistry, including pharmaceutical research and materials science.

Literature

• Chemical clearing and dehydration of GFP expressing mouse brains.

  PloS one 20120101

• Growth of a tropical marine yeast Yarrowia lipolytica NCIM 3589 on bromoalkanes: relevance of cell size and cell surface properties.

  Yeast (Chichester, England) 20111001

• Second monoclinic modification of cyclo-hexane-1,1-dicarbonitrile.

  Acta crystallographica. Section E, Structure reports online 20110701

• 3-(Piperidin-1-ium-1-yl)-6-azoniaspiro-[5.5]undecane dibromide monohydrate.

  Acta crystallographica. Section E, Structure reports online 20110601

• 2-(5-Bromo-pent-yl)-4-chloro-5-[2-(4-meth-oxy-phen-yl)ethyl-amino]-pyridazin-3(2H)-one.

  Acta crystallographica. Section E, Structure reports online 20100901

• Design of group IIA secreted/synovial phospholipase A(2) inhibitors: an oxadiazolone derivative suppresses chondrocyte prostaglandin E(2) secretion.

  PloS one 20100101

• 1-Methyl-4-({5-[(4-methyl-phen-yl)sulfan-yl]pent-yl}sulfan-yl)benzene.

  Acta crystallographica. Section E, Structure reports online 20091201

• Synthesis and evaluation of 1-(1-(Benzo[b]thiophen-2-yl)cyclohexyl)piperidine (BTCP) analogues as inhibitors of trypanothione reductase.

  ChemMedChem 20090803

• Expeditious and convenient synthesis of pregnanes and its glycosides as potential anti-dyslipidemic and anti-oxidant agents.

  Bioorganic & medicinal chemistry 20070701

• Effect of alterations of key active site residues in O6-alkylguanine-DNA Alkyltransferase on its ability to modulate the genotoxicity of 1,2-dibromoethane.

  Chemical research in toxicology 20070101

• Synthesis and biological properties of 2-hydroxy-1-(1-phenyltetralyl)piperidine and some of its intermediates as derivatives of phencyclidine.

  Arzneimittel-Forschung 20050101

• Novel spirocyclic pyrrolidones as P2/P1 mimetics in potent inhibitors of HIV-1 protease.

  Bioorganic & medicinal chemistry letters 20021202