111061-56-4 | Fmoc-Ser(Trt)-OH

Packsize	Purity	Availability	Price	Discounted Price
1g	96%	in stock	$16.00	$11.00
5g	96%	in stock	$23.00	$16.00
10g	96%	in stock	$36.00	$25.00
25g	96%	in stock	$68.00	$47.00
100g	96%	in stock	$206.00	$144.00
500g	96%	in stock	$914.00	$640.00

Description

• Catalog Number: AB74332
• Chemical Name: Fmoc-Ser(Trt)-OH
• CAS Number: 111061-56-4
• Molecular Formula: C37H31NO5
• Molecular Weight: 569.64574
• MDL Number: MFCD00153364
• SMILES: O=C(N[C@H](C(=O)O)COC(c1ccccc1)(c1ccccc1)c1ccccc1)OCC1c2ccccc2-c2c1cccc2

Computed Properties

• Complexity: 837
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 43
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 11
• XLogP3: 7.2

Upstream Synthesis Route

Fmoc-Ser(Trt)-OH is a key building block widely used in chemical synthesis, particularly in the field of peptide synthesis. This compound serves as a protected form of serine amino acid, allowing for selective incorporation into peptide chains during solid-phase peptide synthesis. By utilizing the Fmoc (9-fluorenylmethyloxycarbonyl) protecting group along with the Trt (trityl) protecting group on the serine residue, Fmoc-Ser(Trt)-OH enables efficient and controlled peptide bond formation. This strategy offers chemists the flexibility to introduce serine residues at specific locations within the peptide sequence, leading to the synthesis of complex peptides with high purity and yield. Additionally, the Fmoc protecting group can be readily removed under mild conditions, unveiling the reactive serine functionality for subsequent synthetic steps. In summary, Fmoc-Ser(Trt)-OH plays a crucial role in the precise assembly of peptides with diverse biological activities and structural motifs.