111196-81-7 | 2-Chloro-5-ethylpyrimidine

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$19.00	$13.00
5g	95%	in stock	$37.00	$26.00
25g	95%	in stock	$60.00	$42.00

Description

• Catalog Number: AB61744
• Chemical Name: 2-Chloro-5-ethylpyrimidine
• CAS Number: 111196-81-7
• Molecular Formula: C6H7ClN2
• Molecular Weight: 142.5862
• MDL Number: MFCD00799503
• SMILES: CCc1cnc(nc1)Cl

Computed Properties

• Complexity: 79.1
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 2

Upstream Synthesis Route

2-Chloro-5-ethylpyrimidine is a versatile compound used extensively in chemical synthesis for its unique reactivity and functional group properties. This compound serves as a key building block in the preparation of various pharmaceuticals, agrochemicals, and fine chemicals due to its ability to undergo a wide range of chemical transformations.In organic synthesis, 2-Chloro-5-ethylpyrimidine can be utilized as an alkylating agent, enabling the introduction of the ethyl group into target molecules. This reaction provides a straightforward method to modify and enhance the properties of organic compounds. Additionally, the chlorine atom in the molecule can serve as a leaving group in substitution reactions, facilitating the introduction of new functional groups into organic frameworks.Furthermore, 2-Chloro-5-ethylpyrimidine can participate in Suzuki coupling reactions, allowing for the formation of carbon-carbon bonds under mild reaction conditions. This feature makes it valuable in the construction of complex molecular architectures and the synthesis of biologically active compounds.Overall, the application of 2-Chloro-5-ethylpyrimidine in chemical synthesis highlights its significance as a versatile and indispensable building block for the creation of diverse organic molecules with valuable properties and functionalities.

Literature

• Effects of various bases on acid-catalyzed amination of 2-chloro-5-ethylpyrimidine: synthesis of PPARpan agonist GW693085.

  The Journal of organic chemistry 20100604