1113-59-3 | Bromopyruvic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	96%	in stock	$25.00	$17.00
5g	96%	in stock	$33.00	$23.00
25g	96%	in stock	$73.00	$51.00
100g	96%	in stock	$201.00	$141.00
500g	96%	in stock	$851.00	$596.00

Description

• Catalog Number: AB47366
• Chemical Name: Bromopyruvic acid
• CAS Number: 1113-59-3
• Molecular Formula: C3H3BrO3
• Molecular Weight: 166.9581
• MDL Number: MFCD00149107
• SMILES: OC(=O)C(=O)CBr

Computed Properties

• Complexity: 98.4
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 7
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 0.5

Literature

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  Chemico-biological interactions 20170525

• Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer.

  Journal of bioenergetics and biomembranes 20150101

• Regulation of death induction and chemosensitizing action of 3-bromopyruvate in myeloid leukemia cells: energy depletion, oxidative stress, and protein kinase activity modulation.

  The Journal of pharmacology and experimental therapeutics 20140201

• MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors.

  Nature genetics 20130101

• D-Amino acid oxidase-induced oxidative stress, 3-bromopyruvate and citrate inhibit angiogenesis, exhibiting potent anticancer effects.

  Journal of bioenergetics and biomembranes 20121001

• Glutamine deprivation enhances antitumor activity of 3-bromopyruvate through the stabilization of monocarboxylate transporter-1.

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  Surgery today 20120501

• 3-Bromopyruvate inhibits calcium uptake by sarcoplasmic reticulum vesicles but not SERCA ATP hydrolysis activity.

  The international journal of biochemistry & cell biology 20120501

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• Aerosolized 3-bromopyruvate inhibits lung tumorigenesis without causing liver toxicity.

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• Mefloquine interferes with glycolysis in schistosomula of Schistosoma mansoni via inhibition of enolase.

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  The Biochemical journal 20110801

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