112068-01-6 | (S)-1,1-Diphenylprolinol

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$8.00	$5.00
10g	98%	in stock	$8.00	$6.00
25g	98%	in stock	$12.00	$9.00
100g	98%	in stock	$48.00	$34.00

Description

• Catalog Number: AB55824
• Chemical Name: (S)-1,1-Diphenylprolinol
• CAS Number: 112068-01-6
• Molecular Formula: C17H19NO
• Molecular Weight: 253.3388600000001
• MDL Number: MFCD00075506
• SMILES: OC(c1ccccc1)(c1ccccc1)[C@@H]1CCCN1

Computed Properties

• Complexity: 261
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• XLogP3: 2.7

Literature

• 2-DPMP (desoxypipradrol, 2-benzhydrylpiperidine, 2-phenylmethylpiperidine) and D2PM (diphenyl-2-pyrrolidin-2-yl-methanol, diphenylprolinol): A preliminary review.

  Progress in neuro-psychopharmacology & biological psychiatry 20121203

• Use and acute toxicity associated with the novel psychoactive substances diphenylprolinol (D2PM) and desoxypipradrol (2-DPMP).

  Clinical toxicology (Philadelphia, Pa.) 20120901

• 'Legal highs'--novel and emerging psychoactive drugs: a chemical overview for the toxicologist.

  Clinical toxicology (Philadelphia, Pa.) 20120101

• Clinical toxicology of newer recreational drugs.

  Clinical toxicology (Philadelphia, Pa.) 20111001

• Formation and stability of prolinol and prolinol ether enamines by NMR: delicate selectivity and reactivity balances and parasitic equilibria.

  Journal of the American Chemical Society 20110511

• Organocatalytic approach to polysubstituted piperidines and tetrahydropyrans.

  Organic letters 20110401

• Recreational drugs, 3,4-Methylenedioxymethamphetamine(MDMA), 3,4-methylenedioxyamphetamine (MDA) and diphenylprolinol, inhibit neurite outgrowth in PC12 cells.

  The Journal of toxicological sciences 20100601

• Direct oxidation of beta-aryl substituted aldehydes to alpha,beta-unsaturated aldehydes promoted by an o-anisidine-Pd(OAc)2 co-catalyst.

  Chemistry, an Asian journal 20091102

• Spiroborate ester-mediated asymmetric synthesis of beta-hydroxy ethers and its conversion to highly enantiopure beta-amino ethers.

  The Journal of organic chemistry 20090605

• Catalytic asymmetric oxa-Michael-Michael cascade for facile construction of chiral chromans via an aminal intermediate.

  Organic letters 20090402

• Highly enantio- and diastereoselective organocatalytic cascade aza-Michael-Michael reactions: a direct method for the synthesis of trisubstituted chiral pyrrolidines.

  Chemical communications (Cambridge, England) 20081121

• Cardiovascular toxicity associated with recreational use of diphenylprolinol (diphenyl-2-pyrrolidinemethanol [D2PM]).

  Journal of medical toxicology : official journal of the American College of Medical Toxicology 20080901

• Synthesis of a new C(2)-symmetric chiral catalyst and its application in the catalytic asymmetric borane reduction of prochiral ketones.

  Chirality 20080201

• Organocatalytic enantioselective cascade Michael-alkylation reactions: synthesis of chiral cyclopropanes and investigation of unexpected organocatalyzed stereoselective ring opening of cyclopropanes.

  Journal of the American Chemical Society 20070905

• Enantioselective organocatalytic double Michael addition reactions.

  Organic letters 20070426

• Chiral Diphenylprolinol TES ether promoted conjugate addition-aldol-dehydration reactions between alpha,beta-unsaturated aldehydes and 2-N-protected amino benzaldehydes.

  Organic letters 20070315

• Chiral diphosphites and diphosphoramidites as cheap and efficient ligands in Rh-catalyzed asymmetric olefin hydrogenation.

  Chemical communications (Cambridge, England) 20060604

• Enantioselective addition of diethylzinc to aldehydes catalyzed by optically active C2-symmetrical bis-beta-amino alcohols.

  Chirality 20021001