1121-13-7 | 4-Nitroisoxazole

Packsize	Purity	Availability	Price	Discounted Price
1g	96%	in stock	$251.00	$176.00
5g	96%	in stock	$713.00	$499.00

Description

• Catalog Number: AD65876
• Chemical Name: 4-Nitroisoxazole
• CAS Number: 1121-13-7
• Molecular Formula: C3H2N2O3
• Molecular Weight: 114.0596
• MDL Number: MFCD06638027
• SMILES: [O-][N+](=O)c1conc1

Computed Properties

• Complexity: 99.2
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 4
• XLogP3: 0.2

Upstream Synthesis Route

4-Nitroisoxazole is a versatile compound widely used in chemical synthesis as a key building block for the preparation of various pharmaceuticals, agrochemicals, and other advanced organic compounds. Its unique structure and reactivity make it an essential component in the development of new molecules with diverse functions and properties.One of the main applications of 4-Nitroisoxazole in chemical synthesis is as a precursor for the synthesis of heterocyclic compounds. By undergoing various reductive, acidic, or basic reactions, the nitro group on the isoxazole ring can be selectively modified to introduce different functional groups, such as amines, alkyl groups, or halogens. This versatility allows chemists to tailor the molecular structure of the final compound to achieve specific desired properties, such as bioactivity, stability, or solubility.Additionally, 4-Nitroisoxazole can also be used as a synthetic intermediate for the preparation of important synthetic building blocks, such as amino acids, peptides, or complex natural products. Its ability to participate in diverse synthetic transformations makes it a valuable tool in the creation of novel molecules for various applications in the fields of medicine, materials science, and agriculture.Overall, the versatility and reactivity of 4-Nitroisoxazole make it an indispensable component in the toolkit of synthetic chemists, enabling the efficient and precise construction of complex organic molecules with tailored properties and functions for a wide range of applications in the chemical industry.

Literature

• Catalytic asymmetric 1,6-Michael addition of arylthiols to 3-methyl-4-nitro-5-alkenyl-isoxazoles with bifunctional catalysts.

  The Journal of organic chemistry 20111007