1121-25-1 | 3-Hydroxy-2-methylpyridine

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$9.00	$6.00
5g	98%	in stock	$11.00	$8.00
10g	98%	in stock	$13.00	$9.00
25g	98%	in stock	$21.00	$15.00
100g	98%	in stock	$63.00	$44.00
500g	98%	in stock	$312.00	$219.00

Description

• Catalog Number: AB44588
• Chemical Name: 3-Hydroxy-2-methylpyridine
• CAS Number: 1121-25-1
• Molecular Formula: C6H7NO
• Molecular Weight: 109.1259
• MDL Number: MFCD00082538
• SMILES: Oc1cccnc1C
• NSC Number: 27506

Computed Properties

• Complexity: 74.9
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 0.9

Upstream Synthesis Route

3-Hydroxy-2-Methylpyridine, also known as 3-hydroxynicotinic acid, is a versatile building block in chemical synthesis with valuable applications in the pharmaceutical and agrochemical industries. This compound serves as a key intermediate in the synthesis of various heterocyclic compounds, particularly pyridine derivatives, which are important structural motifs in many biologically active molecules.One of the primary applications of 3-Hydroxy-2-Methylpyridine is as a precursor for the synthesis of pharmaceuticals. It can be used to introduce functional groups or modify existing groups in the drug molecules, enhancing their biological activities or pharmacokinetic properties. Additionally, the presence of a hydroxy group in 3-Hydroxy-2-Methylpyridine allows for further derivatization through various chemical reactions, enabling the synthesis of diverse drug candidates with improved therapeutic profiles.Furthermore, 3-Hydroxy-2-Methylpyridine plays a significant role in the development of agrochemicals by serving as a starting material for the synthesis of pesticides, herbicides, and fungicides. Its structural versatility allows for the incorporation of specific functionalities necessary for targeting pests or weeds while minimizing environmental impact. Coupled with its ease of manipulation in chemical reactions, 3-Hydroxy-2-Methylpyridine facilitates the creation of novel agrochemical compounds with enhanced effectiveness and safety profiles.

Literature

• Synthesis and comparison of antimalarial activity of febrifugine derivatives including halofuginone.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20090501

• Gene identification and characterization of 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase, an NAD+-dependent dismutase.

  Journal of biochemistry 20090401

• The B6 database: a tool for the description and classification of vitamin B6-dependent enzymatic activities and of the corresponding protein families.

  BMC bioinformatics 20090101

• Molecular cloning, identification and characterization of 2-methyl-3-hydroxypyridine-5-carboxylic-acid-dioxygenase-coding gene from the nitrogen-fixing symbiotic bacterium Mesorhizobium loti.

  Journal of bioscience and bioengineering 20061201