1125-40-2 | 5-Hydroxy-3-methylindole

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$41.00	$29.00
1g	98%	in stock	$158.00	$111.00
5g	98%	in stock	$474.00	$332.00

Description

• Catalog Number: AD40145
• Chemical Name: 5-Hydroxy-3-methylindole
• CAS Number: 1125-40-2
• Molecular Formula: C9H9NO
• Molecular Weight: 147.1739
• MDL Number: MFCD03095210
• SMILES: Oc1ccc2c(c1)c(C)c[nH]2

Computed Properties

• Complexity: 149
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 2
• XLogP3: 1.3

Upstream Synthesis Route

3-Methyl-1H-indol-5-ol, also known as $name$, is a valuable chemical compound frequently utilized in chemical synthesis applications. This versatile molecule plays a crucial role in various reactions and processes within the field of organic chemistry. One of the primary applications of 3-Methyl-1H-indol-5-ol in chemical synthesis is as a key building block for the preparation of pharmaceutical compounds. Its unique structure and properties make it a desirable precursor in the synthesis of drug molecules, particularly in the development of pharmaceuticals targeting specific biological pathways or disease states. Furthermore, 3-Methyl-1H-indol-5-ol serves as a vital intermediate in the creation of dyes and pigments. Its aromatic nature and functional groups make it a suitable starting material for the production of colored compounds used in various industries, such as textiles, paints, and plastics.Additionally, this compound is utilized in the synthesis of natural products and fine chemicals, where its structural features are crucial for the formation of complex molecular structures with desirable properties.Overall, 3-Methyl-1H-indol-5-ol plays a significant role in chemical synthesis processes, contributing to the development of a wide range of products essential for pharmaceuticals, dyes, pigments, and other specialized chemicals.

Literature

• The roles of different porcine cytochrome P450 enzymes and cytochrome b5A in skatole metabolism.

  Animal : an international journal of animal bioscience 20120501

• In vitro bioactivation of bazedoxifene and 2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol in human liver microsomes.

  Chemico-biological interactions 20120415

• Metabolism and bioactivation of 3-methylindole by human liver microsomes.

  Chemical research in toxicology 20070101

• Phase II in vitro metabolism of 3-methylindole metabolites in porcine liver.

  Xenobiotica; the fate of foreign compounds in biological systems 20030501