1126320-27-1 | 4-Chloro-2-fluoro-5-methylphenylboronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$325.00	$228.00
1g	98%	in stock	$791.00	$554.00

Description

• Catalog Number: AB59043
• Chemical Name: 4-Chloro-2-fluoro-5-methylphenylboronic acid, pinacol ester
• CAS Number: 1126320-27-1
• Molecular Formula: C13H17BClFO2
• Molecular Weight: 270.5353
• MDL Number: MFCD11855985
• SMILES: CC1(C)OB(OC1(C)C)c1cc(C)c(cc1F)Cl

Computed Properties

• Complexity: 308
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1

Upstream Synthesis Route

2-(4-Chloro-2-fluoro-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a versatile reagent widely utilized in modern chemical synthesis processes. As a boronic ester, it serves as a key building block for the synthesis of various biologically active compounds, pharmaceuticals, agrochemicals, and materials.This compound plays a crucial role in Suziki-Miyaura cross-coupling reactions, allowing for the efficient formation of carbon-carbon bonds under mild reaction conditions. By introducing this boronic ester into the reaction mixture, chemists can selectively modulate the regioselectivity and stereochemistry of the resulting products, enabling the synthesis of complex molecular structures with high efficiency.Moreover, 2-(4-Chloro-2-fluoro-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is valued for its stability and compatibility with a wide range of functional groups, making it a valuable tool for chemists seeking to streamline their synthetic routes and enhance the overall yield and purity of their target compounds.