1127-45-3 | 8-Hydroxyquinoline-N-oxide

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$16.00	$11.00
10g	97%	in stock	$18.00	$13.00
500g	97%	in stock	$705.00	$494.00

Description

• Catalog Number: AI09054
• Chemical Name: 8-Hydroxyquinoline-N-oxide
• CAS Number: 1127-45-3
• Molecular Formula: C9H7NO2
• Molecular Weight: 161.15738000000005
• MDL Number: MFCD18322606
• SMILES: [O-][n+]1cccc2c1c(O)ccc2
• NSC Number: 21656

Computed Properties

• Complexity: 163
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 0.4

Upstream Synthesis Route

8-Hydroxyquinoline 1-oxide, also known as oxine or oxine-N-oxide, plays a crucial role in chemical synthesis as a versatile and valuable reagent. It is widely utilized in various organic transformations due to its unique properties and reactivity. One of the key applications of 8-Hydroxyquinoline 1-oxide is its use as a chelating agent in coordination chemistry. It forms stable complexes with metal ions, making it an essential tool in the preparation and purification of metal-containing compounds. Additionally, 8-Hydroxyquinoline 1-oxide is commonly employed as a ligand in organometallic reactions, facilitating the formation of complex structures with enhanced stability and selectivity. Its ability to coordinate with metal ions enables precise control over reaction pathways and product outcomes in synthetic chemistry. Moreover, 8-Hydroxyquinoline 1-oxide serves as an effective catalyst in various organic transformations, promoting desirable reactions with high efficiency and selectivity. Its versatile applications in chemical synthesis highlight its significance as a valuable reagent in modern research and industrial processes.

Literature

• Identifying chelators for metalloprotein inhibitors using a fragment-based approach.

  Journal of medicinal chemistry 20110127

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501