1127-59-9 | 7-Methyl-1H-indole-2,3-dione

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$15.00	$10.00
1g	97%	in stock	$16.00	$11.00
10g	97%	in stock	$25.00	$17.00
25g	97%	in stock	$56.00	$39.00
100g	97%	in stock	$211.00	$148.00

Description

• Catalog Number: AD63153
• Chemical Name: 7-Methyl-1H-indole-2,3-dione
• CAS Number: 1127-59-9
• Molecular Formula: C9H7NO2
• Molecular Weight: 161.15737999999996
• MDL Number: MFCD00022797
• SMILES: O=C1Nc2c(C1=O)cccc2C
• NSC Number: 3161

Computed Properties

• Complexity: 237
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 1.2

Upstream Synthesis Route

7-Methylindoline-2,3-dione, also known as isatin, serves as a versatile building block in chemical synthesis due to its unique structure and reactivity. This compound is commonly employed in the production of pharmaceuticals, dyes, and other organic compounds.In chemical synthesis, 7-Methylindoline-2,3-dione can act as a precursor for various indole derivatives, which are valuable intermediates in drug development. Its carbonyl group allows for functionalization reactions, enabling the creation of a wide range of derivatives with diverse chemical properties.Furthermore, 7-Methylindoline-2,3-dione can participate in a variety of multi-step synthesis routes, leading to the formation of complex molecules with specific biological activities. Its presence in the synthesis pathway can impart unique structural motifs that contribute to the desired pharmacological or material properties of the final compound.Overall, the use of 7-Methylindoline-2,3-dione in chemical synthesis highlights its importance as a key building block for the efficient and strategic construction of various organic molecules with potential applications across different industries.

Literature

• A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ.

  PloS one 20120101

• Selective inhibition of carboxylesterases by isatins, indole-2,3-diones.

  Journal of medicinal chemistry 20070419

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501