113-92-8 | Chloropheniramine Maleate

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$15.00	$10.00
1g	98%	in stock	$16.00	$11.00
5g	98%	in stock	$25.00	$18.00
25g	98%	in stock	$33.00	$23.00
100g	98%	in stock	$88.00	$62.00
500g	98%	in stock	$275.00	$192.00

Description

• Catalog Number: AB71968
• Chemical Name: Chloropheniramine Maleate
• CAS Number: 113-92-8
• Molecular Formula: C20H23ClN2O4
• Molecular Weight: 390.8606199999999
• MDL Number: MFCD00069225
• SMILES: CN(CCC(c1ccccn1)c1ccc(cc1)Cl)C.OC(=O)C=CC(=O)O
• NSC Number: 759156

Computed Properties

• Complexity: 368
• Covalently-Bonded Unit Count: 2
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 27
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 7
• Undefined Atom Stereocenter Count: 1

Literature

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• Histamine induces MUC5AC expression via a hCLCA1 pathway.

  Pharmacology 20070101

• Development and validation of chemometrics-assisted spectrophotometry and liquid chromatography methods for the simultaneous determination of the active ingredients in two multicomponent mixtures containing chlorpheniramine maleate and phenylpropanolamine hydrochloride.

  Journal of AOAC International 20070101

• Impact of a non-meltable additive on melt agglomeration with a hydrophobic meltable binder in high-shear mixer.

  Pharmaceutical development and technology 20070101

• [Description of an outbreak of lepidopterism (dermatitis associated with contact with moths) among sailors in Salvador, State of Bahia].

  Revista da Sociedade Brasileira de Medicina Tropical 20070101

• Chlorpheniramine and ephedrine in combination for motion sickness.

  Journal of vestibular research : equilibrium & orientation 20070101

• Use of swirling airflow to enhance coating performance of bottom spray fluid bed coaters.

  International journal of pharmaceutics 20061211

• Impact of CYP2D6*10 on H1-antihistamine-induced hypersomnia.

  European journal of clinical pharmacology 20061201

• Extra- and intracellular formation of reactive oxygen species by human neutrophils in the presence of pheniramine, chlorpheniramine and brompheniramine.

  Neuro endocrinology letters 20061201

• Effects of pyrimethamine-sulphadoxine, chloroquine plus chlorpheniramine, and amodiaquine plus pyrimethamine-sulphadoxine on gametocytes during and after treatment of acute, uncomplicated malaria in children.

  Memorias do Instituto Oswaldo Cruz 20061201

• Major degradation product identified in several pharmaceutical formulations against the common cold.

  Analytical chemistry 20061115

• The fabrication and evaluation of inline coupling of microdialysis with capillary electrophoresis and its application in the determination of blood glucose.

  Electrophoresis 20061101

• Yellow urticaria associated with hepatitis type-C liver cirrhosis.

  The Journal of dermatology 20061101

• Can chlorpheniramine cause serotonin syndrome?

  Singapore medical journal 20061101

• Localized expression of histamine H1 receptors in syncytiotrophoblast cells of human placenta.

  Journal of pharmacological sciences 20061101

• [Anesthesia in a woman with cold urticaria].

  Revista espanola de anestesiologia y reanimacion 20061101

• Drugs acting as plasticizers in polymeric systems: a quantitative treatment.

  Journal of controlled release : official journal of the Controlled Release Society 20061027

• Floating hot-melt extruded tablets for gastroretentive controlled drug release system.

  Journal of controlled release : official journal of the Controlled Release Society 20061010

• Vasomodulation of skeletal muscle BOLD signal.

  Journal of magnetic resonance imaging : JMRI 20061001

• Weight-reducing regimen associated with polymorphic ventricular tachycardia.

  The American journal of emergency medicine 20061001

• The effects of alpha1-acid glycoprotein on the reversal of chloroquine resistance in Plasmodium falciparum.

  Annals of tropical medicine and parasitology 20061001

• Involvement of histamine receptors in the acquisition of inhibitory avoidance in Carassius auratus.

  Progress in neuro-psychopharmacology & biological psychiatry 20060930

• Potentiation of antimalarial drug action by chlorpheniramine against multidrug-resistant Plasmodium falciparum in vitro.

  Parasitology international 20060901

• Are any cold medications safe for a person on high blood pressure medication?

  Mayo Clinic women's healthsource 20060901

• Enantiomeric impurity determination in capillary electrophoresis using a highly-sulfated cyclodextrins-based method.

  Biomedical chromatography : BMC 20060801

• Effectiveness of hyperbaric oxygen therapy in idiopathic sudden hearing loss.

  The Journal of laryngology and otology 20060801

• Allergy medication in Japanese volunteers: treatment effect of single doses on nocturnal sleep architecture and next day residual effects.

  Current medical research and opinion 20060701

• Determination of chlorpheniramine and its binding with human serum albumin by capillary electrophoresis with tris(2,2'-bipyridyl)ruthenium(II) electrochemiluminescence detection.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060701

• The interaction and compatibility between a soft contact lens and an ophthalmic drug.

  Eye & contact lens 20060701

• Nasal congestion model in Brown Norway rats and the effects of some H1-antagonists.

  International immunopharmacology 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Antiradical effects of antihistamines in human blood. Structure-activity relationship.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401

• Properties of sustained release hot-melt extruded tablets containing chitosan and xanthan gum.

  International journal of pharmaceutics 20060309

• Quantitative structure-pharmacokinetic relationships for drug clearance by using statistical learning methods.

  Journal of molecular graphics & modelling 20060301

• Evaluation of sodium alginate as drug release modifier in matrix tablets.

  International journal of pharmaceutics 20060217

• Systematic comparison of different functionality columns for a classical pharmaceutical problem.

  Journal of pharmaceutical and biomedical analysis 20060213

• Analysis of pharmaceutical preparations containing antihistamine drugs by micellar liquid chromatography.

  Journal of pharmaceutical and biomedical analysis 20060213

• Simultaneous determination of active ingredients in an ophthalmic solution by isocratic tandem-mode HPLC connected reverse phase column and strong cation exchange column.

  Journal of pharmaceutical and biomedical analysis 20060213

• Simultaneous quantitation of five active principles in a pharmaceutical preparation: development and validation of a near infrared spectroscopic method.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060201

• [Simultaneous determination of ephedrine and chlorpheniramine in human plasma by a highly sensitive liquid chromatography-tandem mass spectrometric method].

  Yao xue xue bao = Acta pharmaceutica Sinica 20060201

• Repeated-dose effects of mequitazine, cetirizine and dexchlorpheniramine on driving and psychomotor performance.

  British journal of clinical pharmacology 20060101

• Chlorpheniramine, selective serotonin-reuptake inhibitors (SSRIs) and over-the-counter (OTC) treatment.

  Medical hypotheses 20060101

• Determination of phenylephrine hydrochloride, chlorpheniramine maleate, and methscopolamine nitrate in tablets or capsules by liquid chromatography with two UV absorbance detectors in series.

  Journal of AOAC International 20060101

• Epinastine hydrochloride antagonism against interleukin-4-mediated T cell cytokine imbalance in vitro.

  International archives of allergy and immunology 20060101

• Biphasic anaphylactic reaction to Ketorolac tromethamine.

  International journal of immunopathology and pharmacology 20060101

• Influence of plasticizer level on the drug release from sustained release film coated and hot-melt extruded dosage forms.

  Pharmaceutical development and technology 20060101

• OTC product: Zicam Cold and Flu Medicated Spoons.

  Journal of the American Pharmacists Association : JAPhA 20060101

• Synergistic action of famotidine and chlorpheniramine on acetic acid-induced chronic gastric ulcer in rats.

  World journal of gastroenterology 20051207

• Study on the enhancement of Ru(bpy)3(2+) electrochemiluminescence by nanogold and its application for pentoxyverine detection.

  Electrophoresis 20051201

• A Cadillac ride to the emergency department.

  Pediatric emergency care 20051201

• Adverse reaction to prophylactic amoxicillin: a case report.

  The European journal of prosthodontics and restorative dentistry 20051201

• Effects of mometasone furoate on a rat allergic rhinitis model.

  European journal of pharmacology 20051107

• The effects of olopatadine hydrochloride on the number of scratching induced by repeated application of oxazolone in mice.

  European journal of pharmacology 20051107

• In vitro evaluation of drug release from self micro-emulsifying drug delivery systems using a biodegradable homolipid from Capra hircus.

  International journal of pharmaceutics 20051104

• Acute urticaria following 'gomutra' (cow's urine) gargles.

  Clinical and experimental dermatology 20051101

• Enhanced antinociception by intracerebroventricularly administered orexin A in histamine H1 or H2 receptor gene knockout mice.

  Pain 20051101

• Maternal drug use, fertility problems, and infant craniostenosis.

  The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 20051101

• Effects of a new isoquinolinone derivative on induction of action potential bursts in central snail neuron.

  Pharmacology 20051001

• Self-management and pregnancy--safe interventions for panic, phobia and other anxiety-disorders might include over-the-counter (OTC) 'SSRI' antihistamines such as diphenhydramine and chlorpheniramine.

  Acta psychiatrica Scandinavica 20051001

• Transport of hydroxyzine and triprolidine across bovine olfactory mucosa: role of passive diffusion in the direct nose-to-brain uptake of small molecules.

  International journal of pharmaceutics 20050930

• Content uniformity and dissolution tests of triplicate mixtures by a double divisor-ratio spectra derivative method.

  Farmaco (Societa chimica italiana : 1989) 20050901

• Acute psychosis with Coricidin cold medicine.

  The Annals of pharmacotherapy 20050901

• Separation and determination of pseudoephedrine, dextromethorphan, diphenhydramine and chlorpheniramine in cold medicines by nonaqueous capillary electrophoresis.

  Journal of pharmaceutical and biomedical analysis 20050901

• Adolescent abuse of dextromethorphan.

  Clinical pediatrics 20050901

• Spontaneous scratching behavior in MRL/lpr mice, a possible model for pruritus in autoimmune diseases, and antipruritic activity of a novel kappa-opioid receptor agonist nalfurafine hydrochloride.

  European journal of pharmacology 20050822

• Apoptosis in rat jejunal mucosa is regulated partly through the central nervous system, which controls feeding behavior.

  Journal of gastroenterology and hepatology 20050801

• Chlorphenamine.

  Nursing times 20050801

• 2-O-(2-hydroxybutyl)-beta-cyclodextrin as a chiral selector for the capillary electrophoretic separation of chiral drugs.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20050801

• Hypersensitivity reactions to oxaliplatin in two asian patients.

  The Annals of pharmacotherapy 20050601

• Coricidin HBP cough and cold addiction.

  Journal of the American Academy of Child and Adolescent Psychiatry 20050601

• Predictors of the failure of treatment with chloroquine plus chlorpheniramine, in children with acute, uncomplicated, Plasmodium falciparum malaria.

  Annals of tropical medicine and parasitology 20050601

• Efficacy of a management plan based on severity assessment in longitudinal and case-controlled studies of 747 children with nut allergy: proposal for good practice.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20050601

• Airway closure after antigen challenge in cynomolgus monkeys: effect of the histamine H1 receptor antagonist, chlorpheniramine maleate.

  International archives of allergy and immunology 20050501

• Synthesis and pharmacological investigation of novel 1-substituted-4-phenyl-1,2,4-triazolo[4,3-a]quinazolin-5(4H)-ones as a new class of H1-antihistaminic agents.

  Bioorganic & medicinal chemistry letters 20050401

• New approaches with two cyano columns to the separation of acetaminophen, phenylephrine, chlorpheniramine and related compounds.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050325

• Effect of combined histamine H1 and H3 receptor blockade on cutaneous microvascular permeability elicited by compound 48/80.

  Life sciences 20050304

• Carrier mediated transport of chlorpheniramine and chlorcyclizine across bovine olfactory mucosa: implications on nose-to-brain transport.

  Journal of pharmaceutical sciences 20050301

• Severe anaphylactic reaction after intracameral antibiotic administration during cataract surgery.

  Journal of cataract and refractive surgery 20050301

• The role of histamine in estradiol-induced conditioned consumption reductions.

  Physiology & behavior 20050131

• A role for the central histaminergic system in the leptin-mediated increase in cardiovascular dynamics.

  Brain research bulletin 20050115

• Cutaneous adverse drug reaction to oral chlorphenamine detected with patch testing.

  Contact dermatitis 20050101

• Sorbitan monopalmitate-based proniosomes for transdermal delivery of chlorpheniramine maleate.

  Drug delivery 20050101

• Molecules acting on receptor level at weaning, durably influence liver glucocorticoid receptors.

  Acta physiologica Hungarica 20050101

• An unusual adverse drug reaction?

  Allergologia et immunopathologia 20050101

• Liquid chromatography and chemometric-assisted spectrophotometric methods for the analysis of two multicomponent mixtures containing cough suppressant drugs.

  Journal of AOAC International 20050101

• Simultaneous determination of some active ingredients in cough and cold preparations by gas chromatography, and method validation.

  Journal of AOAC International 20050101

• Derivative ultraviolet spectrophotometric determination of dexchlorpheniramine maleate in tablets in presence of coloring agents.

  Farmaco (Societa chimica italiana : 1989) 20050101

• Simultaneous determination of chlorpheniramine maleate and dexamethasone in a tablet dosage form by liquid chromatography.

  Journal of AOAC International 20050101

• Acute intoxication of lidocaine and chlorpheniramine: report of one case.

  Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi 20050101

• Prescription of codeine in young infants.

  Hong Kong medical journal = Xianggang yi xue za zhi 20041201

• Drug interaction between methamphetamine and antihistamines: behavioral changes and tissue concentrations of methamphetamine in rats.

  European journal of pharmacology 20041128

• Histamine reduces gap junctional communication of human tonsil high endothelial cells in culture.

  Microvascular research 20041101

• Degranulation of uterine mast cell modifies contractility of isolated myometrium from pregnant women.

  American journal of obstetrics and gynecology 20041101

• Addition of ibuprofen to pseudoephedrine and chlorpheniramine in the treatment of seasonal allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20041101

• To evaluate and compare the effects of first generation anti-histamine (chlorpheniramine maleate) and second generation anti-histamine (loratadine) on isolated trachea of rabbit.

  JPMA. The Journal of the Pakistan Medical Association 20041101

• Commentary on: Severe manifestations of coricidin intoxication.

  The American journal of emergency medicine 20041101

• Enantiomeric separation of basic drugs with partially filled serum albumin as chiral selector in capillary electrophoresis.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20041001

• LC/MS for the degradation profiling of cough-cold products under forced conditions.

  Journal of pharmaceutical and biomedical analysis 20040903

• Effects of Chlorpheniramine and L-histidine on vestibular compensation in goldfish, Carassius auratus.

  Neuroscience letters 20040902

• Severe acquired hemophilia with factor VIII inhibition associated with acetaminophen and chlorpheniramine.

  The Annals of pharmacotherapy 20040901

• Analgesic effects of preincisional administration of dextromethorphan and tenoxicam following laparoscopic cholecystectomy.

  Acta anaesthesiologica Scandinavica 20040901

• Hydroxyzine prevents isolation-induced vocalization in guinea pig pups: comparison with chlorpheniramine and immepip.

  Pharmacology, biochemistry, and behavior 20040901

• Risk factors for gametocyte carriage in uncomplicated falciparum malaria in children.

  Parasitology 20040901

• [A clinical trial to evaluate the efficacy and safety of compound pseudoephedrine hydrochloride sustained release capsule in patients with seasonal allergic rhinitis].

  Zhonghua er bi yan hou ke za zhi 20040901

• A case of probable codeine poisoning in a young infant after the use of a proprietary cough and cold medicine.

  Hong Kong medical journal = Xianggang yi xue za zhi 20040801

• [Experimental study on the pharmacology of 999 ganmaoling, a compound recipe of Chinese and Western materia medica].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040801

• Evaluation of antipruritic effects of several agents on scratching behavior by NC/Nga mice.

  European journal of pharmacology 20040714

• In vitro and ex vivo permeation studies of chlorpheniramine maleate gels prepared by carbomer derivatives.

  Drug development and industrial pharmacy 20040701

• CE versus HPLC for the dissolution test in a pharmaceutical formulation containing acetaminophen, phenylephrine and chlorpheniramine.

  Journal of pharmaceutical and biomedical analysis 20040629

• Pharmacokinetic interactions between phenylpropanolamine, caffeine and chlorpheniramine in rats.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040601

• Retentivity and enantioselectivity of uniformly sized molecularly imprinted polymers for d-chlorpheniramine and -brompheniramine in hydro-organic mobile phases.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040505

• Chlorpheniramine maleate as an alternative to antiemetic cyclizine.

  Journal of pain and symptom management 20040501

• Simultaneous determination of chlorpheniramine and pseudoephedrine in human plasma by liquid chromatography-tandem mass spectrometry.

  Biomedical chromatography : BMC 20040501

• Influence of histamine and H1-receptor antagonists on ejaculated human spermatozoa: role of intrasperm Ca2+.

  Indian journal of experimental biology 20040501

• Parallel infusion of hydrocortisone with/without chlorpheniramine bolus injection to prevent acute adverse reactions to antivenom for snakebites.

  The Medical journal of Australia 20040419

• [Simultaneous determination of pseudoephedrine and chlorpheniramine in human plasma by HPLC-UV detection method].

  Yao xue xue bao = Acta pharmaceutica Sinica 20040401

• Effect of drug solubility and different excipients on floating behaviour and release from glyceryl monooleate matrices.

  International journal of pharmaceutics 20040319

• Up-regulation of histamine H(1) receptors in an allergic rat nasal mucosa model.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040301

• Increase in the level of histidine decarboxylase mRNA expression in nasal mucosa of rats sensitized by toluene diisocyanate.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040301

• Central nervous system side effects of first- and second-generation antihistamines in school children with perennial allergic rhinitis: a randomized, double-blind, placebo-controlled comparative study.

  Pediatrics 20040201

• A dose-ranging study of the effects of mequitazine on actual driving, memory and psychomotor performance as compared to dexchlorpheniramine, cetirizine and placebo.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040201

• Influences of osmotic agents in diffusion layer on drug release from multilayer coated pellets.

  Drug development and industrial pharmacy 20040201

• Involvement of the brain serotonergic system in the locomotor stimulant effects of chlorpheniramine in Wistar rats: implication of postsynaptic 5-HT1A receptors.

  Behavioural brain research 20040105

• Parallel infusion of hydrocortisone +/- chlorpheniramine bolus injection to prevent acute adverse reactions to antivenom for snakebites.

  The Medical journal of Australia 20040105

• Angioedema of the lips and tongue induced by angiotensin-converting enzyme inhibitor. A report of two cases.

  Primary dental care : journal of the Faculty of General Dental Practitioners (UK) 20040101

• Prolonged impact of five imprinters on the serotonin content of white blood cells and mast cells of weanling rats: outstanding effect of benzpyrene and chlorpheniramine.

  Cell biology international 20040101

• Chlorpheniramine for motion sickness.

  Journal of vestibular research : equilibrium & orientation 20040101

• Allergy to dexchlorpheniramine. Study of a case.

  Allergologia et immunopathologia 20040101

• [Herpes gestationis].

  Acta medica portuguesa 20040101

• Rapid identification and quantification of chlorpheniramine maleate or pheniramine maleate in pharmaceutical preparations by thin-layer chromatography-densitometry.

  Journal of AOAC International 20040101

• Haloperidol and chlorpheniramine interaction in inhibitory avoidance in goldfish.

  Behavioural brain research 20031217

• Increased tissue survival in experimental skin flaps in mast cell-deficient rats.

  Acta physiologica Scandinavica 20031201

• Relaxant effects of different fractions of essential oil from Carum copticum on guinea pig tracheal chains.

  Phytotherapy research : PTR 20031201

• Comparative study of acute effects of single doses of fexofenadine, olopatadine, d-chlorpheniramine and placebo on psychomotor function in healthy volunteers.

  Human psychopharmacology 20031201

• Histamine H3 receptors regulate vascular permeability changes in the skin of mast cell-deficient mice.

  International immunopharmacology 20031101

• Massive tongue swelling following the use of synthetic saliva.

  Paediatric anaesthesia 20031101

• Simultaneous determination of paracetamol and chlorpheniramine maleate by micellar electrokinetic chromatography.

  Journal of pharmaceutical and biomedical analysis 20031015

• Neurochemical analysis of brain monoamines after L-histidine and chlorpheniramine administration in goldfish.

  Neuroscience letters 20031009

• Severe manifestations of coricidin intoxication.

  The American journal of emergency medicine 20031001

• HPLC determination of aminophylline, methoxyphenamine hydrochloride, noscapine and chlorphenamine maleate in compound dosage forms with an aqueous-organic mobile phase.

  Journal of pharmaceutical and biomedical analysis 20030915

• A randomized, placebo-controlled trial of the effect of antihistamine or corticosteroid treatment in acute otitis media.

  The Journal of pediatrics 20030901

• The influence of polymeric subcoats and pellet formulation on the release of chlorpheniramine maleate from enteric coated pellets.

  Drug development and industrial pharmacy 20030901

• In vitro release studies of chlorpheniramine maleate from gels prepared by different cellulose derivatives.

  Farmaco (Societa chimica italiana : 1989) 20030801

• Identification of a dual histamine H1/H3 receptor ligand based on the H1 antagonist chlorpheniramine.

  Bioorganic & medicinal chemistry letters 20030616

• Proteinase-activated receptor-2 activation induces uterine contractility in term pregnant rats that is not dependent on mast cell activation and cyclo-oxygenase products.

  American journal of obstetrics and gynecology 20030601

• Antihistamines and potentiation of opioid induced sedation and respiratory depression.

  Anaesthesia 20030501

• Aseptic meningitis associated with intravenous administration of dexchlorpheniramine.

  Annales de medecine interne 20030501

• A new isoquinolinone derivative with noble vasorelaxation activity.

  Pharmacology 20030401

• Poly(ethyleneglycol) column for the determination of acetaminophen, phenylephrine and chlorpheniramine in pharmaceutical formulations.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030305

• Middle ear fluid histamine and leukotriene B4 in acute otitis media: effect of antihistamine or corticosteroid treatment.

  International journal of pediatric otorhinolaryngology 20030301

• Effect of histamine on phasic and tonic contractions of isolated uterine tissue from pregnant women.

  American journal of obstetrics and gynecology 20030301

• Polydrug fatality involving metaxalone.

  Journal of forensic sciences 20030301

• Evaluation of the efficacy of a combined formulation (Grippostad-C) in the therapy of symptoms of common cold: a randomized, double-blind, multicenter trial.

  International journal of clinical pharmacology and therapeutics 20030301

• Panic disorder treated with the antihistamine chlorpheniramine.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030301

• Dual ambroxal and chlorpheniramine resinate as an alternative carrier in concurrent resinate administration.

  Die Pharmazie 20030301

• The anti-allergic effects of a cromolyn sodium-chlorpheniramine combination compared to ketotifen in the conjunctival allergen challenge model.

  European journal of ophthalmology 20030301

• [Effects of central histaminergic receptor activation on carotid sinus baroreceptor reflex resetting in stressed rats].

  Sheng li xue bao : [Acta physiologica Sinica] 20030225

• A chromatographic method for rapid and simultaneous analysis of codeine phosphate, ephedrine HCl and chlorpheniramine maleate in cough-cold syrup formulation.

  Journal of pharmaceutical and biomedical analysis 20030101

• Self-assembly of drug-polymer complexes: a spontaneous nanoencapsulation process monitored by atomic force microscopy.

  Journal of pharmaceutical sciences 20030101

• Histamine H1 receptors in the ventromedial hypothalamus mediate the anorectic action of the pancreatic hormone amylin.

  Peptides 20030101

• Investigation of EDTA anticoagulant in plasma to improve the throughput of liquid chromatography/tandem mass spectrometric assays.

  Rapid communications in mass spectrometry : RCM 20030101

• Two cases of cross-sensitivity in subjects allergic to paraphenylenediamine following ingestion of Polaronil.

  Dermatology (Basel, Switzerland) 20030101

• A model of allergic nasal congestion in dogs sensitized to ragweed.

  American journal of rhinology 20030101

• Determination of chlorpheniramine maleate and tincture ipecac in dosage form by liquid chromatography with ultraviolet detection.

  Journal of AOAC International 20030101

• Anaphylactoid reaction to carboplatin: successful 'desensitization'.

  Allergologia et immunopathologia 20030101

• The effects of a sedative antihistamine, d-chlorpheniramine, on visuomotor spatial discrimination and regional brain activity as measured by positron emission tomography (PET).

  Human psychopharmacology 20021201

• In vivo evidence for a lack of central effect of ebastine, an antihistaminic agent, in rats: a microdialysis study.

  Japanese journal of pharmacology 20021201

• [Herbal medicines and severe adverse effects: uvular angioedema caused by Echballium elaterium].

  Revista medica de Chile 20021201

• Stability of polyethylene oxide in matrix tablets prepared by hot-melt extrusion.

  Biomaterials 20021101

• Clinical pharmacology of H1-antihistamines in the skin.

  The Journal of allergy and clinical immunology 20021101

• Single-dose oral tolerance test with alternative compounds for the management of adverse reactions to drugs.

  International archives of allergy and immunology 20021101

• Influence of thermal processing on the properties of chlorpheniramine maleate tablets containing an acrylic polymer.

  Pharmaceutical development and technology 20021101

• Complementary use of partial least-squares and artificial neural networks for the non-linear spectrophotometric analysis of pharmaceutical samples.

  Analytical and bioanalytical chemistry 20021001

• Simple and sensitive method for the determination of chlorpheniramine maleate in human plasma using liquid chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020905

• Single-patient drug trial methodology for allergic rhinitis.

  The Annals of pharmacotherapy 20020901

• The effects of chloroquine, amodiaquine and chloroquine plus chlorpheniramine on the disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children.

  Annals of tropical medicine and parasitology 20020901

• The involvement of nervous and some inflammatory response mechanisms in the acute snuff-induced gingival hyperaemia in humans.

  Journal of clinical periodontology 20020901

• Histaminergic modulation of stress-induced analgesia and cognitive dysfunction.

  Methods and findings in experimental and clinical pharmacology 20020901

• Sequential atomic force microscopy imaging of a spontaneous nanoencapsulation process.

  International journal of pharmaceutics 20020821

• Transport mechanisms of nicotine across the human intestinal epithelial cell line Caco-2.

  The Journal of pharmacology and experimental therapeutics 20020801

• [The potential P300 in the evaluation of the side effects of dexchlorpheniramine].

  Revista de neurologia 20020801

• Solid-state plasticization of an acrylic polymer with chlorpheniramine maleate and triethyl citrate.

  International journal of pharmaceutics 20020725

• Validation of a HPLC quantification of acetaminophen, phenylephrine and chlorpheniramine in pharmaceutical formulations: capsules and sachets.

  Journal of pharmaceutical and biomedical analysis 20020720

• Combined antiviral-antimediator treatment for the common cold.

  The Journal of infectious diseases 20020715

• [Sudden death attributed to ventricular arrhytmia induced by an over-the-counter drug for influenza].

  Medicina clinica 20020608

• Development of a validated capillary electrophoresis method for enantiomeric purity testing of dexchlorpheniramine maleate.

  Journal of chromatography. A 20020607

• A possible trend suggesting increased abuse from Coricidin exposures reported to the Texas Poison Network: comparing 1998 to 1999.

  Veterinary and human toxicology 20020601

• Enhanced antinociception by intrathecally-administered morphine in histamine H1 receptor gene knockout mice.

  Neuropharmacology 20020601

• [The secondary effects of the antihistamine chlorpheniramine on the central nervous system].

  Revista de neurologia 20020601

• [Research into simultaneous spectrophotometric determination of components in cough syrup by principal component regression method].

  Guang pu xue yu guang pu fen xi = Guang pu 20020601

• The roles of CYP2D6 and stereoselectivity in the clinical pharmacokinetics of chlorpheniramine.

  British journal of clinical pharmacology 20020501

• Hypersensitivity reactions to carboplatin in children.

  Journal of neuro-oncology 20020501

• A protein-encapsulation technique by the sol-gel method for the preparation of monolithic columns for capillary electrochromatography.

  Analytical chemistry 20020415

• Differential cognitive effects of ebastine and (+)-chlorpheniramine in healthy subjects: correlation between cognitive impairment and plasma drug concentration.

  British journal of clinical pharmacology 20020301

• Endogenous mast cell degranulation modulates cervical contractility in the guinea pig.

  American journal of obstetrics and gynecology 20020301

• Uniformly sized molecularly imprinted polymer for d-chlorpheniramine. Evaluation of retention and molecular recognition properties in an aqueous mobile phase.

  Journal of chromatography. A 20020301

• Simultaneous high-performance liquid chromatographic determination of paracetamol, phenylephrine HCl, and chlorpheniramine maleate in pharmaceutical dosage forms.

  Journal of chromatographic science 20020201

• [Clinical study of BRON-L syrup (cough suppressant) abuse].

  Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence 20020201

• Inhibitory effects of H1-antihistamines on CYP2D6- and CYP2C9-mediated drug metabolic reactions in human liver microsomes.

  European journal of clinical pharmacology 20020201

• Antipruritic activity of the kappa-opioid receptor agonist, TRK-820.

  European journal of pharmacology 20020125

• The enantioselective determination of chlorpheniramine and its major metabolites in human plasma using chiral chromatography on a beta-cyclodextrin chiral stationary phase and mass spectrometric detection.

  Journal of pharmaceutical and biomedical analysis 20020115

• Acoustic rhinometry in the dog: a novel large animal model for studies of nasal congestion.

  American journal of rhinology 20020101

• Antihistamines in the management of canine atopic dermatitis: a retrospective study of 171 dogs (1992-1998).

  Veterinary therapeutics : research in applied veterinary medicine 20020101

• Chlorpheniramine is no more effective than placebo in relieving the symptoms of childhood atopic dermatitis with a nocturnal itching and scratching component.

  Dermatology (Basel, Switzerland) 20020101

• Pharmacological characterization of a noninvasive, chronic, experimental dog model of nasal congestion.

  Journal of pharmacological and toxicological methods 20020101

• The diagnosis of lichen-planus-like contact dermatitis to chlorpheniramine maleate.

  Dermatology (Basel, Switzerland) 20020101

• Characterization of nasal obstruction in the allergic guinea pig using the forced oscillation method.

  Journal of pharmacological and toxicological methods 20020101

• Determination of optical purity by nonenantioselective LC using CD detection.

  Journal of pharmaceutical and biomedical analysis 20011201

• Postmortem diffusion of drugs from the bladder into femoral venous blood.

  Forensic science international 20011201

• The H1-receptor antagonist dextro-chlorpheniramine impairs selective auditory attention in the absence of subjective awareness of this impairment.

  Journal of clinical psychopharmacology 20011201

• Absence of mast cell involvement in active systemic anaphylaxis in rats.

  European journal of pharmacology 20011102

• Neuroimaging of histamine H1-receptor occupancy in human brain by positron emission tomography (PET): a comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine.

  British journal of clinical pharmacology 20011101

• Analysis of the effects of CPA and L-histidine on goldfish tested on a conditioned place preference model.

  Behavioural brain research 20011015

• Comparison of intra-accumbens injection of histamine with histamine H1-receptor antagonist chlorpheniramine in effects on reinforcement and memory parameters.

  Behavioural brain research 20011015

• Histaminergic control of oxytocin release in the paraventricular nucleus during lactation in rats.

  Experimental neurology 20011001

• Abuse of Coricidin HBP cough & cold tablets: episodes recorded by a poison center.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20011001

• Rapid and simple determination of histamine-N-methyl transferase activity by high-performance liquid chromatography with UV detection.

  Mediators of inflammation 20011001

• Separation of basic drug enantiomers by capillary electrophoresis using ovoglycoprotein as a chiral selector: comparison of chiral resolution ability of ovoglycoprotein and completely deglycosylated ovoglycoprotein.

  Electrophoresis 20010901

• Randomized comparison of chloroquine and amodiaquine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.

  Annals of tropical medicine and parasitology 20010901

• Controlled clinical study of the efficacy of loratadine in Nigerian patients with allergic rhinitis.

  The Nigerian postgraduate medical journal 20010901

• Roles of mast cells and sensory nerves in cutaneous vascular hyperpermeability and scratching behavior induced by poly-L-arginine in rats.

  European journal of pharmacology 20010817

• Influence of chlorpheniramine maleate on topical hydroxypropylcellulose films produced by hot-melt extrusion.

  Pharmaceutical development and technology 20010801

• Influence of plasticization time, curing conditions, storage time, and core properties on the drug release from Aquacoat-coated pellets.

  Pharmaceutical development and technology 20010801

• Painless thyroiditis induced by the cessation of betamethasone.

  Internal medicine (Tokyo, Japan) 20010801

• Prophylaxis of vasovagal reaction with Atrohist Plus.

  Archives of ophthalmology (Chicago, Ill. : 1960) 20010701

• Neuronal histamine release elicited by hyperthermia mediates tracheal dilation and pressor response.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010601

• Intestinal absorption and metabolism of chlorpheniramine enantiomers in rat.

  Chirality 20010505

• Histamine H3 receptor-mediated inhibition of sympathetically evoked mydriasis in rats.

  European journal of pharmacology 20010504

• Synthesis of iron-crosslinked chitosan succinate and iron-crosslinked hydroxamated chitosan succinate and their in vitro evaluation as potential matrix materials for oral theophylline sustained-release beads.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010501

• [Simultaneous determination of chlorpheniramine, paracetamol and pseudo-ephedrine hydrochloride in composite tablets by high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20010501

• Newer antihistamines.

  The Medical letter on drugs and therapeutics 20010430

• Norbinaltorphimine, a selective kappa-opioid receptor antagonist, induces an itch-associated response in mice.

  European journal of pharmacology 20010420

• Systemic bioavailability of nasally applied chlorphenamine maleate (0.4% nasal spray) relative to tablets administered perorally.

  International journal of clinical pharmacology and therapeutics 20010401

• [Determination of three components in compound chlorophenamine tablet by iterative target transformation factor analysis].

  Guang pu xue yu guang pu fen xi = Guang pu 20010401

• Allergic contact dermatitis due to both chlorpheniramine maleate and dibucaine hydrochloride in an over-the-counter medicament.

  Contact dermatitis 20010101

• Separation of cold medicine ingredients by capillary electrophoresis.

  Electrophoresis 20010101

• pH-independent large-volume sample stacking of positive or negative analytes in capillary electrophoresis.

  Electrophoresis 20010101

• Spectrophotometric and some thermodynamic parameters of the charge transfer complexation between chloranilic acid and chlorpheniramine.

  Bollettino chimico farmaceutico 20010101

• Stereospecific versus nonstereospecific assessments for the bioequivalence of two formulations of racemic chlorpheniramine.

  Chirality 20000801

• A new model of allergic rhinitis in rats by topical sensitization and evaluation of H(1)-receptor antagonists.

  Immunopharmacology 20000601

• Central nervous system effects of H1-receptor antagonists in the elderly.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 19990201

• Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C9*3 allele.

  Pharmacogenetics 19990201

• Binding of chlorpheniramine enantiomers to human plasma proteins.

  Chirality 19990101

• [Dexchlorpheniramine-induced acute hepatitis: a case with positive rechallenge].

  Gastroenterologie clinique et biologique 19981001

• Stereoselective N-demethylation of chlorpheniramine by rat-liver microsomes and the involvement of cytochrome P450 isozymes.

  The Journal of pharmacy and pharmacology 19970301

• The role of histaminergic-noradrenergic axis in naloxone-induced withdrawal symptoms in mice.

  Pharmacology, biochemistry, and behavior 19960901

• Benefit/risk ratio of the antihistamines (H1-receptor antagonists) terfenadine and chlorpheniramine in children.

  The Journal of pediatrics 19940601

• Role of cysteinyl-leukotrienes and histamine in mediating intrinsic tone in isolated human bronchi.

  American journal of respiratory and critical care medicine 19940101

• Proconvulsant effect of ketotifen, a histamine H1 antagonist, confirmed by the use of d-chlorpheniramine with monitoring electroencephalography.

  Methods and findings in experimental and clinical pharmacology 19930401

• Drug-induced acute pulmonary edema--sequential changes in CT images.

  Radiation medicine 19910101

• A comparison of acrivastine versus chlorpheniramine in the treatment of chronic idiopathic urticaria.

  The Journal of international medical research 19890101

• Multicenter, double-blind, multiple-dose, parallel-groups efficacy and safety trial of azelastine, chlorpheniramine, and placebo in the treatment of spring allergic rhinitis.

  The Journal of allergy and clinical immunology 19881101

• Antihistaminic-opioid combination: effect on locomotor activity in mice.

  Polish journal of pharmacology and pharmacy 19880101

• Pharmacologic analysis of LY188695 (KB-2413), 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)-benzimidazole difumarate, a potent histamine1 receptor antagonist.

  Agents and actions 19870201

• Antihistaminics enhance morphine-, but not amphetamine- and scopolamine-induced hyperactivity in mice.

  Psychopharmacology 19870101

• Enhancement of morphine-induced hyperactivity by antihistaminic drugs in mice.

  Archives internationales de pharmacodynamie et de therapie 19861201

• Histamine antagonists and d-tubocurarine-induced hypotension in cardiac surgical patients.

  Clinical pharmacology and therapeutics 19861101

• Atrioventricular conduction block caused by phenylpropanolamine.

  JAMA 19850510

• Visual hallucinations induced by a sympathomimetic drug.

  Canadian Medical Association journal 19841115

• Reaction to phenylpropalamine/chlorpheniramine/belladonna compound in a women with unrecognised autonomic dysfunction.

  Lancet (London, England) 19820731

• Pharmacokinetics of chlorpheniramine after intravenous and oral administration in normal adults.

  European journal of clinical pharmacology 19820101

• The I antigen as an immune complex receptor in a case of haemolytic anaemia induced by an antihistaminic agent.

  British journal of haematology 19810901

• Death attributed to ventricular arrhythmia induced by thioridazine in combination with a single Contac C capsule.

  Canadian Medical Association journal 19781007

• Aplastic anaemia after prolonged treatment with chlorpheniramine.

  Lancet (London, England) 19770305

• Oral facial dyskinesia accociated with prolonged use of antihistaminic decongestants.

  The New England journal of medicine 19750904

• Involuntary movements caused by phenytoin intoxication in epileptic patients.

  Journal of neurology, neurosurgery, and psychiatry 19750301

• Adverse general reactions to high doses of methylglucamine-based contrast media.

  The British journal of radiology 19740901

• Toxic epidermal necrolysis associated with pentazocine therapy and severe reversible renal failure.

  The British journal of dermatology 19730301

• Psychotic episodes associated with the use of common proprietary decongestants.

  The American journal of psychiatry 19661001