1130067-34-3 | CAY10594

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$65.00	$45.00
5mg	98%	in stock	$283.00	$198.00
10mg	98%	in stock	$501.00	$351.00
25mg	98%	in stock	$1,092.00	$765.00

Description

• Catalog Number: AD37335
• Chemical Name: CAY10594
• CAS Number: 1130067-34-3
• Molecular Formula: C26H28N4O2
• Molecular Weight: 428.5261
• MDL Number: MFCD18382100
• SMILES: O=C(c1ccc2c(c1)cccc2)NCCN1CCC2(CC1)C(=O)NCN2c1ccccc1

Computed Properties

• Complexity: 669
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 32
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 5
• XLogP3: 3.9

Literature

• Design, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor.

  Journal of medicinal chemistry 20100923

• Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part II. Identification of the 1,3,8-triazaspiro[4,5]decan-4-one privileged structure that engenders PLD2 selectivity.

  Bioorganic & medicinal chemistry letters 20090415

• Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness.

  Nature chemical biology 20090201