113118-81-3 | 5-Bromonicotinaldehyde

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$13.00	$9.00
10g	98%	in stock	$26.00	$18.00
25g	98%	in stock	$54.00	$38.00

Description

• Catalog Number: AB45258
• Chemical Name: 5-Bromonicotinaldehyde
• CAS Number: 113118-81-3
• Molecular Formula: C6H4BrNO
• Molecular Weight: 186.0061
• MDL Number: MFCD03265758
• SMILES: Brc1cc(C=O)cnc1

Computed Properties

• Complexity: 107
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 1

Upstream Synthesis Route

5-Bromopyridine-3-Carboxaldehyde, also known as $name$, is a versatile compound widely used in chemical synthesis. Its application extends to various fields due to its unique properties and reactivity.1. Synthesis of Heterocyclic Compounds:
5-Bromopyridine-3-Carboxaldehyde serves as a key building block in the synthesis of various heterocyclic compounds, particularly in the pharmaceutical industry. Its structure provides a platform for the introduction of different functional groups, allowing for the creation of complex molecules with diverse biological activities.2. Cross-Coupling Reactions:
Due to the presence of a bromine atom, 5-Bromopyridine-3-Carboxaldehyde is often used in cross-coupling reactions, such as Suzuki-Miyaura and Negishi couplings. These reactions enable the formation of carbon-carbon bonds, facilitating the creation of new carbon frameworks in organic molecules.3. Transition Metal Catalysis:
The electron-deficient nature of the bromopyridine moiety in 5-Bromopyridine-3-Carboxaldehyde makes it a suitable substrate for transition metal-catalyzed reactions. These reactions play a crucial role in the construction of complex organic molecules with high efficiency and selectivity.4. Ligand Synthesis:
5-Bromopyridine-3-Carboxaldehyde can be utilized in the synthesis of ligands for transition metal complexes. By modifying the aldehyde group or introducing substituents on the pyridine ring, tailored ligands can be developed for specific catalytic applications in both academia and industry.5. Functional Group Transformations:
The aldehyde group in 5-Bromopyridine-3-Carboxaldehyde allows for a variety of functional group transformations, including oxidation, reduction, and derivatization. These transformations enhance the versatility of the compound and enable its utilization in a wide range of synthetic processes.Overall, 5-Bromopyridine-3-Carboxaldehyde plays a crucial role in chemical synthesis, offering chemists a valuable tool for the construction of complex molecules and the development of novel compounds with diverse applications.