1133931-02-8 | 4-Chlorothiophene-2-boronic acid

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$480.00	$336.00
250mg	98%	in stock	$946.00	$662.00
1g	98%	in stock	$2,811.00	$1,968.00

Description

• Catalog Number: AA10678
• Chemical Name: 4-Chlorothiophene-2-boronic acid
• CAS Number: 1133931-02-8
• Molecular Formula: C4H4BClO2S
• Molecular Weight: 162.4024
• MDL Number: MFCD03095139
• SMILES: OB(c1scc(c1)Cl)O

Computed Properties

• Complexity: 103
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1

Upstream Synthesis Route

4-Chlorothiophene-2-boronic acid is a versatile building block in organic synthesis, particularly in the field of pharmaceuticals and agrochemicals. This compound serves as a key intermediate in the production of various organic molecules due to its unique reactivity and functional group compatibility. When utilized in chemical synthesis, 4-Chlorothiophene-2-boronic acid plays a crucial role as a boron-containing coupling partner in Suzuki-Miyaura cross-coupling reactions. This powerful synthetic method enables the efficient formation of carbon-carbon bonds, facilitating the construction of complex molecular structures. By incorporating 4-Chlorothiophene-2-boronic acid into synthetic routes, chemists can access a wide range of substituted thiophenes, which are essential structural motifs in many biologically active compounds. Furthermore, the presence of the chlorine and boronic acid functionalities in this molecule imparts valuable properties and functionalization opportunities for further derivatization, making it a valuable tool in the design and synthesis of novel chemical entities.