114-83-0 | 1-Acetyl-2-phenylhydrazine

Packsize	Purity	Availability	Price	Discounted Price
5g	97%	in stock	$13.00	$9.00
25g	97%	in stock	$34.00	$24.00
100g	97%	in stock	$90.00	$63.00
500g	97%	in stock	$251.00	$176.00

Description

• Catalog Number: AA13123
• Chemical Name: 1-Acetyl-2-phenylhydrazine
• CAS Number: 114-83-0
• Molecular Formula: C8H10N2O
• Molecular Weight: 150.1778
• MDL Number: MFCD00008672
• SMILES: CC(=O)NNc1ccccc1

Computed Properties

• Complexity: 130
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 0.7

Upstream Synthesis Route

Acetic acid, 2-phenylhydrazide, also known as phenylhydrazine acetate, serves a crucial role in chemical synthesis as a versatile building block and reagent. This compound is commonly employed in organic reactions to introduce functional groups or form complexes with various organic molecules. Its reactivity allows for the formation of hydrazones, which are important intermediates in the synthesis of various pharmaceuticals, agrochemicals, and natural products. Additionally, acetic acid, 2-phenylhydrazide is utilized in the preparation of hydrazones for identifying carbonyl compounds and in the development of analytical methods. Its ability to undergo condensation reactions with aldehydes and ketones makes it a valuable tool in the creation of diverse chemical compounds.

Literature

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  International journal of molecular sciences 20120101

• [Studies on influence of Siwu decoction and its composite drugs on chemical-induced blood-deficiency model mice].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110901

• Nutritional support in the treatment of aplastic anemia.

  Nutrition (Burbank, Los Angeles County, Calif.) 20110101

• [Effect and its mechanism of Coptis chinensis on oxidative hemolysis of erythrocytes in mice induced by acetylphenylhydrazine].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901

• High activity antioxidant enzymes protect flying-fox haemoglobin against damage: an evolutionary adaptation for flight?

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20061101

• Flow cytometric analysis of erythropoietic abnormality: changes in the cell maturity index of reticulocytes and retic distribution index are useful as indicators of erythropoietic toxicity in non-clinical studies.

  The Journal of toxicological sciences 20060501

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  Anticancer research 20020101

• Acetylphenylhydrazine induced haemoglobin oxidation in erythrocytes studied by Mössbauer spectroscopy.

  Biochimica et biophysica acta 20011107

• Cisplatin-associated anemia: an erythropoietin deficiency syndrome.

  The Journal of clinical investigation 19950401