1142090-23-0 | Gsk2256294a

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$179.00	$125.00
2mg	99%	in stock	$289.00	$202.00
5mg	95%	in stock	$378.00	$264.00
10mg	95%	in stock	$600.00	$420.00
50mg	95%	in stock	$1,200.00	$840.00
100mg	95%	in stock	$1,586.00	$1,110.00

Description

• Catalog Number: AE11481
• Chemical Name: Gsk2256294a
• CAS Number: 1142090-23-0
• Molecular Formula: C21H24F3N7O
• Molecular Weight: 447.4568
• MDL Number: MFCD27987923
• SMILES: CNc1nc(N[C@H]2CCC[C@H](C2)C(=O)NCc2ccc(cc2C(F)(F)F)C#N)nc(n1)C

Upstream Synthesis Route

The chemical compound GSK 2256294, also known as EZH2i, is a potent and selective inhibitor of the enzyme Enhancer of Zeste Homolog 2 (EZH2). EZH2 is a histone methyltransferase that plays a crucial role in epigenetic regulation, specifically in the methylation of histone H3 at lysine 27 (H3K27). In chemical synthesis, GSK 2256294 can be utilized as a valuable tool for studying the role of EZH2 in epigenetic regulation and its potential implications in various diseases, particularly cancer. By targeting EZH2, GSK 2256294 can modulate gene expression patterns and contribute to the development of novel therapeutic strategies. Furthermore, GSK 2256294 can be integrated into synthetic pathways to explore the influence of EZH2 inhibition on specific biochemical processes and pathways. Its selective inhibitory properties make it a promising candidate for designing new compounds with enhanced biological activity and therapeutic potential. Overall, GSK 2256294 holds significant promise for advancing our understanding of epigenetic mechanisms and may pave the way for innovative approaches in chemical synthesis and drug discovery.