AA14224
Packsize | Purity | Availability | Price | Discounted Price | Quantity | |
---|---|---|---|---|---|---|
1mg | 98% | in stock | $63.00 | $45.00 | - + | |
10mg | 98% | in stock | $172.00 | $120.00 | - + | |
25mg | 98% | in stock | $275.00 | $192.00 | - + | |
50mg | 98% | in stock | $461.00 | $323.00 | - + | |
100mg | 98% | in stock | $872.00 | $610.00 | - + |
*All products are for research use only and not intended for human or animal use.
*All prices are in USD.
Catalog Number: | AA14224 |
Chemical Name: | 4-Piperidinecarboxamide, 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)- |
CAS Number: | 1143532-39-1 |
Molecular Formula: | C21H25ClN6O2 |
Molecular Weight: | 428.9152 |
MDL Number: | MFCD22628785 |
SMILES: | OCC[C@@H](c1ccc(cc1)Cl)NC(=O)C1(N)CCN(CC1)c1ncnc2c1cc[nH]2 |
Complexity: | 580 |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 1 |
Heavy Atom Count: | 30 |
Hydrogen Bond Acceptor Count: | 6 |
Hydrogen Bond Donor Count: | 4 |
Rotatable Bond Count: | 6 |
XLogP3: | 1.7 |
AZD5363, a potent and selective inhibitor of the PI3K pathway, plays a crucial role in chemical synthesis as a valuable tool for investigating intracellular signaling pathways. Its ability to inhibit AKT kinases, which are integral in mediating cell proliferation and survival, makes it a key component in studying various cellular processes involved in cancer, metabolic disorders, and other diseases. In chemical synthesis, AZD5363 can be utilized to modulate specific signaling pathways to understand their impact on cellular functions and to develop targeted therapies. Its application in research can lead to the discovery of new drug candidates and provide insights into the molecular mechanisms underlying disease pathology.