114676-91-4 | 1-tert-Butyl 2-methyl (2s,4r)-4-{[tert-butyl(dimethyl)silyl]oxy}-1,2-pyrrolidinedicarboxylate

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Description

• Catalog Number: AA19270
• Chemical Name: 1-tert-Butyl 2-methyl (2s,4r)-4-{[tert-butyl(dimethyl)silyl]oxy}-1,2-pyrrolidinedicarboxylate
• CAS Number: 114676-91-4
• Molecular Formula: C17H33NO5Si
• Molecular Weight: 359.5331
• MDL Number: MFCD05662430
• SMILES: COC(=O)[C@@H]1C[C@H](CN1C(=O)OC(C)(C)C)O[Si](C(C)(C)C)(C)C

Computed Properties

• Complexity: 478
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 24
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 7

Upstream Synthesis Route

The 1-(tert-Butyl) 2-methyl (2S,4R)-4-((tert-butyldimethylsilyl)oxy)pyrrolidine-1,2-dicarboxylate is a versatile compound commonly employed in chemical synthesis for the selective protection of the hydroxyl groups in various organic molecules. This compound acts as a robust protecting group, shielding specific functional groups during reactions to prevent undesired side reactions or to enable the manipulation of a molecule's reactivity.In organic synthesis, the 1-(tert-Butyl) 2-methyl (2S,4R)-4-((tert-butyldimethylsilyl)oxy)pyrrolidine-1,2-dicarboxylate can be strategically incorporated into a molecule to protect the hydroxyl groups, which are prone to unwanted reactivity under certain reaction conditions. By introducing this compound as a protecting group, chemists can selectively control the chemical transformation of the target molecule, allowing for precise modifications to be made at other functional groups without affecting the protected hydroxyl moieties.Moreover, the use of this compound in chemical synthesis facilitates the synthesis of complex organic molecules by providing a means to manipulate the reactivity and selectivity of the functional groups present in the starting materials. Through the strategic installation and subsequent removal of the protecting group, chemists can orchestrate intricate synthetic pathways to access structurally diverse and biologically relevant compounds with high precision.Overall, the application of 1-(tert-Butyl) 2-methyl (2S,4R)-4-((tert-butyldimethylsilyl)oxy)pyrrolidine-1,2-dicarboxylate in chemical synthesis offers a powerful tool for synthetic chemists to conduct controlled and efficient organic transformations, ultimately contributing to the development of novel materials, pharmaceuticals, and other valuable compounds.