114798-26-4 | Losartan

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$6.00	$4.00
250mg	98%	in stock	$7.00	$5.00
1g	98%	in stock	$9.00	$6.00
5g	98%	in stock	$11.00	$8.00
10g	98%	in stock	$13.00	$9.00
25g	98%	in stock	$26.00	$18.00
100g	98%	in stock	$77.00	$54.00

Description

• Catalog Number: AA19533
• Chemical Name: Losartan
• CAS Number: 114798-26-4
• Molecular Formula: C22H23ClN6O
• Molecular Weight: 422.9106
• MDL Number: MFCD00865831
• SMILES: CCCCc1nc(c(n1Cc1ccc(cc1)c1ccccc1c1n[nH]nn1)CO)Cl
• NSC Number: 758699

Computed Properties

• Complexity: 520
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 30
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 8
• XLogP3: 4.3

Literature

• Perindopril, fosinopril and losartan inhibited the progression of diethylnitrosamine-induced hepatocellular carcinoma in mice via the inactivation of nuclear transcription factor kappa-B.

  Toxicology letters 20181001

• Angiotensin II facilitates neointimal formation by increasing vascular smooth muscle cell migration: Involvement of APE/Ref-1-mediated overexpression of sphingosine-1-phosphate receptor 1.

  Toxicology and applied pharmacology 20180515

• Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.

  Chemico-biological interactions 20170801

• Mitogen-activated protein kinase p38 target regenerating islet-derived 3γ expression is upregulated in cardiac inflammatory response in the rat heart.

  Physiological reports 20161001

• Investigation into the interaction of losartan with human serum albumin and glycated human serum albumin by spectroscopic and molecular dynamics simulation techniques: A comparison study.

  Chemico-biological interactions 20160925

• [Mechanism of losartan suppressing vascular calcification in rat aortic artery].

  Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20160801

• Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension in NHE3-deficient mice with transgenic rescue of NHE3 in small intestines.

  Physiological reports 20151101

• Perinatally administered losartan augments renal ACE2 expression but not cardiac or renal Mas receptor in spontaneously hypertensive rats.

  Journal of cellular and molecular medicine 20150801

• Identification and Functional Assessment of a New CYP2C9 Allelic Variant CYP2C9*59.

  Drug metabolism and disposition: the biological fate of chemicals 20150801

• Losartan attenuates paraquat-induced pulmonary fibrosis in rats.

  Human & experimental toxicology 20150501

• TSC-22 up-regulates collagen 3a1 gene expression in the rat heart.

  BMC cardiovascular disorders 20150101

• Hypoxia induces dysregulation of local renin-angiotensin system in mouse Lewis lung carcinoma cells.

  Genetics and molecular research : GMR 20141212

• Oral administration of bisphenol A induces high blood pressure through angiotensin II/CaMKII-dependent uncoupling of eNOS.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20141101

• Chronic infusion of enalaprilat into hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension and cardiac hypertrophy by restoring neurotransmitters and cytokines.

  Toxicology and applied pharmacology 20140201

• Involvement of the HIF-1α and Wnt/β-catenin pathways in the protective effects of losartan on fatty liver graft with ischaemia/reperfusion injury.

  Clinical science (London, England : 1979) 20140101

• Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).

  Toxicological sciences : an official journal of the Society of Toxicology 20131201

• A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.

  Toxicological sciences : an official journal of the Society of Toxicology 20131101

• Rational design, efficient syntheses and biological evaluation of N,N'-symmetrically bis-substituted butylimidazole analogs as a new class of potent Angiotensin II receptor blockers.

  European journal of medicinal chemistry 20130401

• Treatment with low-dose atorvastatin, losartan, and their combination increases expression of vasoactive-related genes in rat aortas.

  Journal of cardiovascular pharmacology and therapeutics 20130301

• Epigallocatechin gallate, the major component of polyphenols in green tea, inhibits telomere attrition mediated cardiomyocyte apoptosis in cardiac hypertrophy.

  International journal of cardiology 20130120

• Angiotensin type 1 receptor autoantibody from preeclamptic patients induces human fetoplacental vasoconstriction.

  Journal of cellular physiology 20130101

• Pro-inflammatory role of angiotensin II in mercuric chloride-induced nephropathy in rats.

  Journal of immunotoxicology 20130101

• Recurrent exposure to subclinical lipopolysaccharide increases mortality and induces cardiac fibrosis in mice.

  PloS one 20130101

• Impaired endocytosis in proximal tubule from subchronic exposure to cadmium involves angiotensin II type 1 and cubilin receptors.

  BMC nephrology 20130101

• Transient prehypertensive treatment in spontaneously hypertensive rats: a comparison of losartan and amlodipine regarding long-term blood pressure, cardiac and renal protection.

  International journal of molecular medicine 20121201

• Recent developments in the diagnosis of Marfan syndrome and related disorders.

  The Medical journal of Australia 20121105

• Podocyte detachment and reduced glomerular capillary endothelial fenestration promote kidney disease in type 2 diabetic nephropathy.

  Kidney international 20121101

• Comparison of medium-dose losartan/hydrochlorothiazide and maximal-dose angiotensin II receptor blockers in the treatment of Japanese patients with uncontrolled hypertension: the Kobe-CONNECT Study.

  Hypertension research : official journal of the Japanese Society of Hypertension 20121101

• The vitamin D receptor activator paricalcitol prevents fibrosis and diastolic dysfunction in a murine model of pressure overload.

  The Journal of steroid biochemistry and molecular biology 20121101

• Microtubules and angiotensin II receptors contribute to modulation of repolarization induced by ventricular pacing.

  Heart rhythm 20121101

• Outcome of venom bradykinin potentiating factor on rennin-angiotensin system in irradiated rats.

  International journal of radiation biology 20121101

• TGFβ signaling: its role in fibrosis formation and myopathies.

  Current opinion in rheumatology 20121101

• Acute ethanol intake induces superoxide anion generation and mitogen-activated protein kinase phosphorylation in rat aorta: a role for angiotensin type 1 receptor.

  Toxicology and applied pharmacology 20121101

• eNOS deficiency predisposes podocytes to injury in diabetes.

  Journal of the American Society of Nephrology : JASN 20121101

• On the different roles of AT1 and AT2 receptors in stretch-induced changes of connexin43 expression and localisation.

  Pflugers Archiv : European journal of physiology 20121101

• A multi-center, double-blind, randomized, parallel group study to evaluate the effects of two different doses of losartan on morbidity and mortality in Chinese patients with symptomatic heart failure intolerant of angiotensin converting enzyme inhibitor treatment.

  Chinese medical journal 20121101

• Superoxide anions modulate the effects of angiotensin-(1-7) in the rostral ventrolateral medulla on cardiac sympathetic afferent reflex and sympathetic activity in rats.

  Neuroscience 20121025

• Central angiotensin II-induced Alzheimer-like tau phosphorylation in normal rat brains.

  FEBS letters 20121019

• β-Arrestin-biased AT1R stimulation promotes cell survival during acute cardiac injury.

  American journal of physiology. Heart and circulatory physiology 20121015

• Skimmin, a coumarin, suppresses the streptozotocin-induced diabetic nephropathy in wistar rats.

  European journal of pharmacology 20121005

• Advanced glycation end products (AGE) induce the receptor for AGE in the colonic mucosa of azoxymethane-injected Fischer 344 rats fed with a high-linoleic acid and high-glucose diet.

  Journal of gastroenterology 20121001

• Regression of ECG-LVH is associated with lower risk of new-onset heart failure and mortality in patients with isolated systolic hypertension; The LIFE study.

  American journal of hypertension 20121001

• Angiotensin II increases CTGF expression via MAPKs/TGF-β1/TRAF6 pathway in atrial fibroblasts.

  Experimental cell research 20121001

• Losartan, an angiotensin II type 1 receptor blocker, ameliorates cerebral ischemia-reperfusion injury via PI3K/Akt-mediated eNOS phosphorylation.

  Brain research bulletin 20121001

• AT1 antagonism and renin inhibition in mice: pivotal role of targeting angiotensin II in chronic kidney disease.

  American journal of physiology. Renal physiology 20121001

• Treatment of idiopathic pulmonary fibrosis with losartan: a pilot project.

  Lung 20121001

• Angiotensin II-induced mitochondrial reactive oxygen species and peroxiredoxin-3 expression in cardiac fibroblasts.

  Journal of hypertension 20121001

• Evaluation of water uptake and mechanical properties of blended polymer films for preparing gas-generated multiple-unit floating drug delivery systems.

  Journal of pharmaceutical sciences 20121001

• Regulation of aortic extracellular matrix synthesis via noradrenergic system and angiotensin II in juvenile rats.

  Pharmaceutical biology 20121001

• Dysregulated renin-angiotensin-aldosterone system contributes to pulmonary arterial hypertension.

  American journal of respiratory and critical care medicine 20121001

• Fraction SX of maitake mushroom favorably influences blood glucose levels and blood pressure in streptozotocin-induced diabetic rats.

  Journal of medicinal food 20121001

• Similarities and differences between effects of angiotensin III and angiotensin II on human prostate cancer cell migration and proliferation.

  Peptides 20121001

• Renal protection of losartan 50 mg in normotensive Chinese patients with nondiabetic chronic kidney disease.

  Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20121001

• Antihypertensive effects of olmesartan compared with other angiotensin receptor blockers: a meta-analysis.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20121001

• Angiotensin II promotes iron accumulation and depresses PGI₂ and NO synthesis in endothelial cells: effects of losartan and propranolol analogs.

  Canadian journal of physiology and pharmacology 20121001

• [AII antagonists (candesartan and irbesartan) in the treatment of cardiovascular diseases].

  Vnitrni lekarstvi 20121001

• Apocynum venetum leaf extract, an antihypertensive herb, inhibits rat aortic contraction induced by angiotensin II: a nitric oxide and superoxide connection.

  Journal of ethnopharmacology 20120928

• A primary culture of distal convoluted tubules expressing functional thiazide-sensitive NaCl transport.

  American journal of physiology. Renal physiology 20120915

• Vitamin D receptor activation and downregulation of renin-angiotensin system attenuate morphine-induced T cell apoptosis.

  American journal of physiology. Cell physiology 20120915

• Characterization of the in vivo antiplatelet activity of the antihypertensive agent losartan.

  Journal of cardiovascular pharmacology and therapeutics 20120901

• Cardiovascular actions of angiotensin-(1-12) in the hypothalamic paraventricular nucleus of the rat are mediated via angiotensin II.

  Experimental physiology 20120901

• The effect of losartan and carvedilol on renal haemodynamics and altered metabolism in fructose-fed Sprague-Dawley rats.

  Journal of physiology and biochemistry 20120901

• Combined treatment with a dipeptidyl peptidase-IV inhibitor (sitagliptin) and an angiotensin II type 1 receptor blocker (losartan) promotes islet regeneration via enhanced differentiation of pancreatic progenitor cells.

  Diabetes, obesity & metabolism 20120901

• Characterization of Angiotensin-(1-7) effects on the cardiovascular system in an experimental model of type-1 diabetes.

  Pharmacological research 20120901

• Rosiglitazone inhibits angiotensin II-induced C-reactive protein production in human aortic endothelial cells through regulating AT(1)-ROS-MAPK signal pathway.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120901

• Contrasting hemodynamic mechanisms of losartan- vs. atenolol-based antihypertensive treatment: a LIFE study.

  American journal of hypertension 20120901

• Effects of CYP2C9*1/*3 and *1/*13 on the pharmacokinetics of losartan and its active metabolite E-3174.

  International journal of clinical pharmacology and therapeutics 20120901

• Perinatal nicotine exposure increases vulnerability of hypoxic-ischemic brain injury in neonatal rats: role of angiotensin II receptors.

  Stroke 20120901

• AT1a receptor signaling is required for basal and water deprivation-induced urine concentration in AT1a receptor-deficient mice.

  American journal of physiology. Renal physiology 20120901

• Captopril intake decreases body weight gain via angiotensin-(1-7).

  Peptides 20120901

• Efficacy and effect on plasma B-type natriuretic peptide concentration of losartan-hydrochlorothiazide for hypertension uncontrolled by losartan-based therapy: subanalysis of a Multicentre Prospective Observational Study.

  Arzneimittel-Forschung 20120901

• Angiotensin II type 2 receptor-mediated inhibition of NaCl absorption is blunted in thick ascending limbs from Dahl salt-sensitive rats.

  Hypertension (Dallas, Tex. : 1979) 20120901

• The discovery of new potent non-peptide Angiotensin II AT1 receptor blockers: a concise synthesis, molecular docking studies and biological evaluation of N-substituted 5-butylimidazole derivatives.

  European journal of medicinal chemistry 20120901

• A combination of vitamin C and losartan for cisplatin-induced nephrotoxicity in rats.

  Iranian journal of kidney diseases 20120901

• Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells.

  Regulatory peptides 20120820

• Resveratrol attenuates angiotensin II-induced senescence of vascular smooth muscle cells.

  Regulatory peptides 20120820

• Angiotensin-(3-4) counteracts the Angiotensin II inhibitory action on renal Ca2+-ATPase through a cAMP/PKA pathway.

  Regulatory peptides 20120820

• Salt-induced downregulation of renal aquaporins is prevented by losartan.

  Regulatory peptides 20120820

• HIV-induced kidney cell injury: role of ROS-induced downregulated vitamin D receptor.

  American journal of physiology. Renal physiology 20120815

• Exercise training normalizes enhanced sympathetic activation from the paraventricular nucleus in chronic heart failure: role of angiotensin II.

  American journal of physiology. Regulatory, integrative and comparative physiology 20120815

• IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancy.

  American journal of physiology. Regulatory, integrative and comparative physiology 20120815

• Effect of AT1 receptor blockade on intermittent hypoxia-induced endothelial dysfunction.

  Respiratory physiology & neurobiology 20120815

• Differential effects of late-life initiation of low-dose enalapril and losartan on diastolic function in senescent Fischer 344 x Brown Norway male rats.

  Age (Dordrecht, Netherlands) 20120801

• Cardiac remodeling and function following exercise and angiotensin II receptor antagonism.

  European journal of applied physiology 20120801

• Renin activates PI3K-Akt-eNOS signalling through the angiotensin AT₁ and Mas receptors to modulate central blood pressure control in the nucleus tractus solitarii.

  British journal of pharmacology 20120801

• Modulation of thiopental-induced vascular relaxation and contraction by perivascular adipose tissue and endothelium.

  British journal of anaesthesia 20120801

• Losartan attenuates human monocyte-derived dendritic cell immune maturation via downregulation of lectin-like oxidized low-density lipoprotein receptor-1.

  Journal of cardiovascular pharmacology 20120801

• Aspirin downregulates angiotensin type 1 receptor transcription implications in capillary formation from endothelial cells.

  Journal of cardiovascular pharmacology 20120801

• Impact of serum uric acid on renal function and cardiovascular events in hypertensive patients treated with losartan.

  Hypertension research : official journal of the Japanese Society of Hypertension 20120801

• A novel method for the determination of the site of glucuronidation by ion mobility spectrometry-mass spectrometry.

  Drug metabolism and disposition: the biological fate of chemicals 20120801

• Angiotensin II enhances AT1-Nox1 binding and stimulates arterial smooth muscle cell migration and proliferation through AT1, Nox1, and interleukin-18.

  American journal of physiology. Heart and circulatory physiology 20120801

• Biased agonism of the angiotensin II type 1 receptor.

  Mini reviews in medicinal chemistry 20120801

• Induction of angiotensin-converting enzyme and activation of the renin-angiotensin system contribute to 20-hydroxyeicosatetraenoic acid-mediated endothelial dysfunction.

  Arteriosclerosis, thrombosis, and vascular biology 20120801

• Treatment of diastolic dysfunction in hypertension.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20120801

• Synthesis and biological evaluation of 4'-[(benzimidazole-1-yl)methyl]biphenyl-2-sulfonamide derivatives as dual angiotensin II/endothelin A receptor antagonists.

  Bioorganic & medicinal chemistry 20120801

• Association of pulse pressure with new-onset atrial fibrillation in patients with hypertension and left ventricular hypertrophy: the Losartan Intervention For Endpoint (LIFE) reduction in hypertension study.

  Hypertension (Dallas, Tex. : 1979) 20120801

• Liquid chromatography-mass spectrometric determination of losartan and its active metabolite on dried blood spots.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120801

• Implication of multiple signaling pathways in the regulation of angiotensin II induced enhanced expression of Giα proteins in vascular smooth muscle cells.

  Canadian journal of physiology and pharmacology 20120801

• Role of chymase in diabetic nephropathy.

  Experimental biology and medicine (Maywood, N.J.) 20120801

• Simvastatin and losartan differentially and synergistically inhibit atherosclerosis in apolipoprotein e(-/-) mice.

  Korean circulation journal 20120801

• Losartan vs candesartan for heart failure.

  JAMA 20120725

• A brain leptin-renin angiotensin system interaction in the regulation of sympathetic nerve activity.

  American journal of physiology. Heart and circulatory physiology 20120715

• Design, synthesis and biological activity of 6-substituted carbamoyl benzimidazoles as new nonpeptidic angiotensin II AT₁ receptor antagonists.

  Bioorganic & medicinal chemistry 20120715

• Plasma fibrin clot properties in arterial hypertension and their modification by antihypertensive medication.

  Thrombosis research 20120701

• Losartan prevents the development of the pro-inflammatory monocytes CD14+CD16+ in haemodialysis patients.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120701

• Effects of angiotensin receptor blockers on endothelial nitric oxide release: the role of eNOS variants.

  British journal of clinical pharmacology 20120701

• Search for the molecular basis of ultra-rapid CYP2C9-catalysed metabolism: relationship between SNP IVS8-109A>T and the losartan metabolism phenotype in Swedes.

  European journal of clinical pharmacology 20120701

• Combination therapy with an angiotensin II receptor blocker and an HMG-CoA reductase inhibitor in experimental subtotal nephrectomy.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120701

• Angiotensin III induces c-Jun N-terminal kinase leading to proliferation of rat astrocytes.

  Neurochemical research 20120701

• Impaired sodium excretion and salt-sensitive hypertension in corin-deficient mice.

  Kidney international 20120701

• Angiotensin II type 2 receptor-dependent increase in nitric oxide synthase activity in the endothelium of db/db mice is mediated via a MEK pathway.

  Pharmacological research 20120701

• Angiotensin II type I receptor and miR-155 in endometrial cancers: synergistic antiproliferative effects of anti-miR-155 and losartan on endometrial cancer cells.

  Gynecologic oncology 20120701

• The relationship between lung inflammation and cardiovascular disease.

  American journal of respiratory and critical care medicine 20120701

• The velocity of antihypertensive effect of losartan/hydrochlorothiazide and angiotensin II receptor blocker.

  Journal of hypertension 20120701

• Involvement of enhanced cardiac sympathetic afferent reflex in sympathetic activation in early stage of diabetes.

  Journal of applied physiology (Bethesda, Md. : 1985) 20120701

• Angiotensin AT(1) receptor inhibition-induced apoptosis by RhoA GTPase activation and pERK1/2 signaling pathways in neonatal obstructive nephropathy.

  Histology and histopathology 20120701

• Effect of phosphatidylinositol 3-kinase-γ inhibitor CAY10505 in hypertension, and its associated vascular endothelium dysfunction in rats.

  Canadian journal of physiology and pharmacology 20120701

• Dose-modifying factor for captopril for mitigation of radiation injury to normal lung.

  Journal of radiation research 20120701

• [Inhibitory effect of losartan on prostatic hyperplasia in spontaneous hypertension rats and its pathophysiological mechanism].

  Zhonghua nan ke xue = National journal of andrology 20120701

• Telmisartan inhibits vascular dysfunction and inflammation via activation of peroxisome proliferator-activated receptor-γ in subtotal nephrectomized rat.

  European journal of pharmacology 20120615

• Combination exenatide-sitagliptin therapy used with glipizide in a patient with type 2 diabetes mellitus.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120615

• The Ghent Marfan Trial--a randomized, double-blind placebo controlled trial with losartan in Marfan patients treated with β-blockers.

  International journal of cardiology 20120614

• MMP-2 regulates Erk1/2 phosphorylation and aortic dilatation in Marfan syndrome.

  Circulation research 20120608

• Prevention of type 2 diabetes and its complications in developing countries: a review.

  International journal of behavioral medicine 20120601

• Angiotensin II type 1 (AT-1) receptor inhibition partially prevents the urodynamic and detrusor changes associated with bladder outlet obstruction: a mouse model.

  BJU international 20120601

• Inhibition of the renin-angiotensin system downregulates tissue factor and vascular endothelial growth factor in human breast carcinoma cells.

  Thrombosis research 20120601

• The relationship of electrocardiographic left ventricular hypertrophy to decreased serum potassium.

  Blood pressure 20120601

• Impact of glycaemic control on the effect of direct renin inhibition in the AVOID study.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20120601

• Influence of diabetes on efficacy of aliskiren, losartan or both on left ventricular mass regression.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20120601

• Association of heart failure hospitalizations with combined electrocardiography and echocardiography criteria for left ventricular hypertrophy.

  American journal of hypertension 20120601

• Angiotensin converting enzyme 2 contributes to sex differences in the development of obesity hypertension in C57BL/6 mice.

  Arteriosclerosis, thrombosis, and vascular biology 20120601

• Comparison of the efficacy and safety of fixed-dose amlodipine/losartan and losartan in hypertensive patients inadequately controlled with losartan: a randomized, double-blind, multicenter study.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20120601

• Losartan versus atenolol-based antihypertensive treatment reduces cardiovascular events especially well in elderly patients: the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study.

  Journal of hypertension 20120601

• Temporal alterations in vascular angiotensin receptors and vasomotor responses in offspring of protein-restricted rat dams.

  American journal of obstetrics and gynecology 20120601

• The second sodium pump: from the function to the gene.

  Pflugers Archiv : European journal of physiology 20120601

• Aldosterone does not require angiotensin II to activate NCC through a WNK4-SPAK-dependent pathway.

  Pflugers Archiv : European journal of physiology 20120601

• Oral aripiprazole-induced severe hypoglycemia.

  Therapeutic drug monitoring 20120601

• The role of AT1 receptor-mediated reproductive function in renovascular hypertension in male rats.

  Hormones and behavior 20120601

• Clinical and molecular approaches to individualize antihypertensive drug therapy.

  Annals of medicine 20120601

• Efficacy/safety of olmesartan medoxomil versus losartan potassium in naïve versus previously treated subjects with hypertension.

  Advances in therapy 20120601

• A new transgenic rat model overexpressing the angiotensin II type 2 receptor provides evidence for inhibition of cell proliferation in the outer adrenal cortex.

  American journal of physiology. Endocrinology and metabolism 20120515

• Angiotensin AT1 receptor-associated protein Arap1 in the kidney vasculature is suppressed by angiotensin II.

  American journal of physiology. Renal physiology 20120515

• Des-aspartate-angiotensin I exerts antiviral effects and attenuates ICAM-1 formation in rhinovirus-infected epithelial cells.

  European journal of pharmacology 20120515

• Effects of proangiotensin-12 infused continuously over 14 days in conscious rats.

  European journal of pharmacology 20120515

• Activating autoantibodies to the angiotensin II type I receptor play an important role in mediating hypertension in response to adoptive transfer of CD4+ T lymphocytes from placental ischemic rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20120515

• Role of angiotensin II in the brain inflammatory events during experimental diabetes in rats.

  Brain research 20120509

• Angiotensin II induces protein overexpression of hyperpolarization-activated cyclic nucleotide-gated channels in primary cultured nodose neurons.

  Neuroscience letters 20120502

• Animal models of cardiorenal syndrome: a review.

  Heart failure reviews 20120501

• Myosin binding protein C: implications for signal-transduction.

  Journal of muscle research and cell motility 20120501

• LPS-stimulated cytokine production in type I cells is modulated by the renin-angiotensin system.

  American journal of respiratory cell and molecular biology 20120501

• Pierson syndrome in an adolescent girl with nephrotic range proteinuria but a normal GFR.

  Pediatric nephrology (Berlin, Germany) 20120501

• Comparison of the efficacy and safety of azilsartan with that of candesartan cilexetil in Japanese patients with grade I-II essential hypertension: a randomized, double-blind clinical study.

  Hypertension research : official journal of the Japanese Society of Hypertension 20120501

• AT1 receptor blockade delays postlactational mammary gland involution: a novel role for the renin angiotensin system.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120501

• Early treatment with olmesartan prevents juxtamedullary glomerular podocyte injury and the onset of microalbuminuria in type 2 diabetic rats.

  American journal of hypertension 20120501

• RhoA guanine exchange factor expression profile in arteries: evidence for a Rho kinase-dependent negative feedback in angiotensin II-dependent hypertension.

  American journal of physiology. Cell physiology 20120501

• Angiotensin II type 2 receptor-coupled nitric oxide production modulates free radical availability and voltage-gated Ca2+ currents in NTS neurons.

  American journal of physiology. Regulatory, integrative and comparative physiology 20120501

• Emphysema in an adult with galactosialidosis linked to a defect in primary elastic fiber assembly.

  Molecular genetics and metabolism 20120501

• An initial reduction in serum uric acid during angiotensin receptor blocker treatment is associated with cardiovascular protection: a post-hoc analysis of the RENAAL and IDNT trials.

  Journal of hypertension 20120501

• Angiotensin-(1-7) administration reduces oxidative stress in diabetic bone marrow.

  Endocrinology 20120501

• Peroxisome proliferator-activated receptor-γ activation with angiotensin II type 1 receptor blockade is pivotal for the prevention of blood-brain barrier impairment and cognitive decline in type 2 diabetic mice.

  Hypertension (Dallas, Tex. : 1979) 20120501

• High-sensitivity liquid chromatography-tandem mass spectrometry for the simultaneous determination of five drugs and their cytochrome P450-specific probe metabolites in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120501

• Circadian variations in exsorptive transport: in situ intestinal perfusion data and in vivo relevance.

  Chronobiology international 20120501

• Losartan, a therapeutic candidate in congenital muscular dystrophy: studies in the dy(2J) /dy(2J) mouse.

  Annals of neurology 20120501

• Bioequivalence study of two losartan tablet formulations with special emphasis on cardiac safety.

  International journal of clinical pharmacology and therapeutics 20120501

• Antihypertensive drugs in patients treated with antiretrovirals.

  The Annals of pharmacotherapy 20120501

• [Effects of ligustrazine on the mitochondrial structure and functions in the process myocardial hypertrophy].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20120501

• Efficacy/safety of olmesartan medoxomil versus losartan potassium in patients by stage 1 or 2 hypertension.

  Postgraduate medicine 20120501

• Angiotensin II plays a critical role in alcohol-induced cardiac nitrative damage, cell death, remodeling, and cardiomyopathy in a protein kinase C/nicotinamide adenine dinucleotide phosphate oxidase-dependent manner.

  Journal of the American College of Cardiology 20120417

• Synthesis and biological evaluation of novel potent angiotensin II receptor antagonists with anti-hypertension effect.

  Bioorganic & medicinal chemistry 20120415

• Losartan's affinity to fluid bilayers modulates lipid-cholesterol interactions.

  Physical chemistry chemical physics : PCCP 20120414

• Association of treatment with losartan vs candesartan and mortality among patients with heart failure.

  JAMA 20120411

• Decreased anandamide transporter activity and calcitonin gene-related peptide production in spontaneously hypertensive rats: role of angiotensin II.

  European journal of pharmacology 20120405

• Angiotensin-II induced nitric oxide production during buffalo sperm capacitation and acrosome reaction.

  Research in veterinary science 20120401

• Pharmacokinetics of losartan and its active carboxylic acid metabolite E-3174 in five ethnic populations of China.

  Journal of clinical pharmacy and therapeutics 20120401

• Racial differences in sudden cardiac death among hypertensive patients during antihypertensive therapy: the LIFE study.

  Heart rhythm 20120401

• The protective effect of losartan in the nephropathy of the diabetic rat includes the control of monoamine oxidase type A activity.

  Pharmacological research 20120401

• Antihypertensive effect of a fixed-dose combination of losartan/hydrochlorothiazide in patients with uncontrolled hypertension: a multicenter study.

  Clinical and experimental nephrology 20120401

• Revelation on the potency of α(1) -blockers - parallel blockade of angiotensin II receptor: a new finding.

  Pharmaceutical biology 20120401

• Dual RAS blockade normalizes angiotensin-converting enzyme-2 expression and prevents hypertension and tubular apoptosis in Akita angiotensinogen-transgenic mice.

  American journal of physiology. Renal physiology 20120401

• Exposure of luminal membranes of LLC-PK1 cells to ANG II induces dimerization of AT1/AT2 receptors to activate SERCA and to promote Ca2+ mobilization.

  American journal of physiology. Renal physiology 20120401

• Angiotensin II induces tumor necrosis factor-α expression and release from cultured human podocytes.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120401

• Oral simvastatin reduces the hypertensive response to air-jet stress.

  Clinical and experimental pharmacology & physiology 20120401

• Diabetes and hypertension: is there a common metabolic pathway?

  Current atherosclerosis reports 20120401

• Receptor activator of nuclear factor-κB ligand is a novel inducer of myocardial inflammation.

  Cardiovascular research 20120401

• New losartan-hydrocaffeic acid hybrids as antihypertensive-antioxidant dual drugs: Ester, amide and amine linkers.

  European journal of medicinal chemistry 20120401

• Impact of lower achieved blood pressure on outcomes in hypertensive patients.

  Journal of hypertension 20120401

• Occipital nerve block is effective in craniofacial neuralgias but not in idiopathic persistent facial pain.

  The journal of headache and pain 20120401

• Is losartan the drug for all seasons?

  Current opinion in pharmacology 20120401

• Regulation of muscle microcirculation in health and diabetes.

  Diabetes & metabolism journal 20120401

• Effect of eplerenone, a selective aldosterone blocker, on the development of diabetic nephropathy in type 2 diabetic rats.

  Diabetes & metabolism journal 20120401

• A case of near total aortic replacement in an adolescent with loeys-dietz syndrome.

  Korean circulation journal 20120401

• Effects of weight change on clinical outcomes in overweight and obese patients with acute myocardial infarction who underwent successful percutaneous coronary intervention.

  Chonnam medical journal 20120401

• Analysis of cytotoxicity induced by proinflammatory cytokines in the human alveolar epithelial cell line A549.

  Bioscience trends 20120401

• The effect of leflunomide on cold and vibratory sensation in patients with rheumatoid arthritis.

  Annals of rehabilitation medicine 20120401

• Angiotensin II stimulates epithelial sodium channels in the cortical collecting duct of the rat kidney.

  American journal of physiology. Renal physiology 20120315

• Angiotensin-(1-7)-induced activation of ERK1/2 is cAMP/protein kinase A-dependent in glomerular mesangial cells.

  American journal of physiology. Renal physiology 20120315

• Angiotensin AT1 receptor blockers suppress oxidized low-density lipoprotein-derived formation of foam cells.

  European journal of pharmacology 20120315

• Aspirin suppresses cardiac fibroblast proliferation and collagen formation through downregulation of angiotensin type 1 receptor transcription.

  Toxicology and applied pharmacology 20120315

• A re-appraisal of volume status and renal function impairment in chronic heart failure: combined effects of pre-renal failure and venous congestion on renal function.

  Heart failure reviews 20120301

• New roles for renin and prorenin in heart failure and cardiorenal crosstalk.

  Heart failure reviews 20120301

• Physiological regulation of extracellular matrix collagen and elastin in the arterial wall of rats by noradrenergic tone and angiotensin II.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

• Effect of fixed-dose losartan/hydrochlorothiazide on brain natriuretic peptide in patients with hypertension.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

• Comparative effectiveness of individual angiotensin receptor blockers on risk of mortality in patients with chronic heart failure.

  Pharmacoepidemiology and drug safety 20120301

• Impact of aliskiren treatment on urinary aldosterone levels in patients with type 2 diabetes and nephropathy: an AVOID substudy.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

• Abilities of candesartan and other AT(1) receptor blockers to impair angiotensin II-induced AT(1) receptor activation after wash-out.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

• Elevated N-terminal pro-brain natriuretic peptide levels predict an enhanced anti-hypertensive and anti-proteinuric benefit of dietary sodium restriction and diuretics, but not angiotensin receptor blockade, in proteinuric renal patients.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120301

• (Pro)renin receptor: another member of the system controlled by angiotensin II?

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

• Comparative effects of different modes of renin angiotensin system inhibition on hypercholesterolaemia-induced atherosclerosis.

  British journal of pharmacology 20120301

• Effects of losartan on whole body, skeletal muscle and vascular insulin responses in obesity/insulin resistance without hypertension.

  Diabetes, obesity & metabolism 20120301

• Physiological regulation of MMPs and tPA/PAI in the arterial wall of rats by noradrenergic tone and angiotensin II.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

• Qiliqiangxin inhibits the development of cardiac hypertrophy, remodeling, and dysfunction during 4 weeks of pressure overload in mice.

  Journal of cardiovascular pharmacology 20120301

• Influence of ramiprilat and losartan on ischemia reperfusion injury in rat hearts.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

• Effect of changing heart rate during treatment of hypertension on incidence of heart failure.

  The American journal of cardiology 20120301

• Role of angiotensin and endothelin in testicular ischemia reperfusion injury.

  International journal of urology : official journal of the Japanese Urological Association 20120301

• Enalapril reverses high-fat diet-induced alterations in cytochrome P450-mediated eicosanoid metabolism.

  American journal of physiology. Endocrinology and metabolism 20120301

• Antihypertensive efficacy of the losartan/hydrochlorothiazide combination and its effect on plasma B-type natriuretic peptide in hypertensive patients uncontrolled by angiotensin II type 1 receptor antagonist-based therapy: a multicentre prospective observational study.

  Clinical drug investigation 20120301

• Reno-protective effects of renin-angiotensin system blockade in type 2 diabetic patients: a systematic review and network meta-analysis.

  Diabetologia 20120301

• Binding of losartan to angiotensin AT1 receptors increases dopamine D1 receptor activation.

  Journal of the American Society of Nephrology : JASN 20120301

• Sympathetic signatures of cardiovascular disease: a blueprint for development of targeted sympathetic ablation therapies.

  Hypertension (Dallas, Tex. : 1979) 20120301

• Central angiotensin type 1 receptor blockade decreases cardiac but not renal sympathetic nerve activity in heart failure.

  Hypertension (Dallas, Tex. : 1979) 20120301

• Tannic acid down-regulates the angiotensin type 1 receptor through a MAPK-dependent mechanism.

  Molecular endocrinology (Baltimore, Md.) 20120301

• Automated data extraction--a feasible way to construct patient registers of primary care utilization.

  Upsala journal of medical sciences 20120301

• Have we observed the implications of the acute fall in eGFR during treatment with losartan?

  Kidney international 20120301

• Pre-renal success.

  Kidney international 20120301

• Angiotensin II receptor antagonist reduces subsequent uterine arterial dysfunction in pregnant offspring of protein-restricted rat dams.

  The journal of obstetrics and gynaecology research 20120301

• Efficacy and tolerability of fimasartan, a new angiotensin receptor blocker, compared with losartan (50/100 mg): a 12-week, phase III, multicenter, prospective, randomized, double-blind, parallel-group, dose escalation clinical trial with an optional 12-week extension phase in adult Korean patients with mild-to-moderate hypertension.

  Clinical therapeutics 20120301

• The role of ARBs alone or with HCTZ in the treatment of hypertension and prevention of cardiovascular and renal complications.

  Postgraduate medicine 20120301

• Biological approaches to improve skeletal muscle healing after injury and disease.

  Birth defects research. Part C, Embryo today : reviews 20120301

• Effects of Losartan vs. Enalapril on the Markers of Metabolic Syndrome.

  Oman medical journal 20120301

• Subtle issues in model specification and estimation of marginal structural models.

  Pharmacoepidemiology and drug safety 20120301

• Losartan potassium loaded sustained release matrix tablets: Influence of various hydrophilic and hydrophobic polymers on drug release behaviour.

  Journal of pharmacy & bioallied sciences 20120301

• Angiotensin-converting enzyme-2 overexpression improves left ventricular remodeling and function in a rat model of diabetic cardiomyopathy.

  Journal of the American College of Cardiology 20120221

• Role of angiotensin II-mediated AMPK inactivation on obesity-related salt-sensitive hypertension.

  Biochemical and biophysical research communications 20120217

• Median preoptic nucleus and subfornical organ drive renal sympathetic nerve activity via a glutamatergic mechanism within the paraventricular nucleus.

  American journal of physiology. Regulatory, integrative and comparative physiology 20120215

• Synthesis and antihypertensive activity of pyrimidin-4(3H)-one derivatives as losartan analogue for new angiotensin II receptor type 1 (AT1) antagonists.

  Bioorganic & medicinal chemistry letters 20120215

• Aliskiren combined with losartan in immunoglobulin A nephropathy: an open-labeled pilot study.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120201

• Prenatal complex congenital heart disease with Loeys-Dietz syndrome.

  Cardiology in the young 20120201

• Effect of angiotensin receptor blockade on insulin sensitivity and endothelial function in abdominally obese hypertensive patients with impaired fasting glucose.

  Clinical science (London, England : 1979) 20120201

• Repeated administration of berberine inhibits cytochromes P450 in humans.

  European journal of clinical pharmacology 20120201

• Antihypertensive effects and safety of eprosartan: a meta-analysis of randomized controlled trials.

  European journal of clinical pharmacology 20120201

• Losartan exerts no protective effects against acute pulmonary embolism-induced hemodynamic changes.

  Naunyn-Schmiedeberg's archives of pharmacology 20120201

• Cerebral microvascular inflammation in DOCA salt-induced hypertension: role of angiotensin II and mitochondrial superoxide.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120201

• Angiotensin II induces nephrin dephosphorylation and podocyte injury: role of caveolin-1.

  Cellular signalling 20120201

• Plasma and tissue concentrations of proangiotensin-12 in rats treated with inhibitors of the renin-angiotensin system.

  Hypertension research : official journal of the Japanese Society of Hypertension 20120201

• Losartan inhibits conventional dendritic cell maturation and Th1 and Th17 polarization responses: Νovel mechanisms of preventive effects on lipopolysaccharide-induced acute lung injury.

  International journal of molecular medicine 20120201

• Impact of alcohol habits and smoking on the risk of new-onset atrial fibrillation in hypertensive patients with ECG left ventricular hypertrophy: the LIFE study.

  Blood pressure 20120201

• Modulation of renal superoxide dismutase by telmisartan therapy in C57BL/6-Ins2(Akita) diabetic mice.

  Hypertension research : official journal of the Japanese Society of Hypertension 20120201

• Co-administration of haloperidol and drugs affecting the angiotensin pathway: effect on the extrapyramidal system.

  Toxicology mechanisms and methods 20120201

• Effects of losartan and amlodipine alone or combined with simvastatin in hypertensive patients with nonalcoholic hepatic steatosis.

  European journal of gastroenterology & hepatology 20120201

• Aldosterone-induced brain MAPK signaling and sympathetic excitation are angiotensin II type-1 receptor dependent.

  American journal of physiology. Heart and circulatory physiology 20120201

• Regulation of peroxisome proliferator-activated receptor-γ by angiotensin II via transforming growth factor-β1-activated p38 mitogen-activated protein kinase in aortic smooth muscle cells.

  Arteriosclerosis, thrombosis, and vascular biology 20120201

• Angiotensin type 2 receptor agonist compound 21 reduces vascular injury and myocardial fibrosis in stroke-prone spontaneously hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 20120201

• Mineralocorticoid receptor blocker eplerenone improves endothelial function and inhibits Rho-associated kinase activity in patients with hypertension.

  Clinical pharmacology and therapeutics 20120201

• Evaluation of the dose-response relationship of amlodipine and losartan combination in patients with essential hypertension: an 8-week, randomized, double-blind, factorial, phase II, multicenter study.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20120201

• The therapeutic tradeoff between the adverse impacts of a lower GFR and long-term renal protection.

  Kidney international 20120201

• Telmisartan exerts renoprotective actions via peroxisome proliferator-activated receptor-γ/hepatocyte growth factor pathway independent of angiotensin II type 1 receptor blockade.

  Hypertension (Dallas, Tex. : 1979) 20120201

• Evidence-based hypertension treatment in patients with diabetes.

  Journal of clinical hypertension (Greenwich, Conn.) 20120201

• Assessment of prescribers' knowledge of the cost of medications.

  The Annals of pharmacotherapy 20120201

• Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.

  PLoS genetics 20120201

• The Williams-Beuren Syndrome-a window into genetic variants leading to the development of cardiovascular disease.

  PLoS genetics 20120201

• [Perindopril and losartan attenuate intrahepatic Toll-like receptor 4 protein expression in rats with bile duct ligation-induced hepatic fibrosis].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120201

• Severe neutropenia in a renal transplant patient suggesting an interaction between mycophenolate and fenofibrate.

  Current drug safety 20120201

• miR-29b participates in early aneurysm development in Marfan syndrome.

  Circulation research 20120120

• Prolonged effects of intracerebroventricular angiotensin II on drinking, eating and locomotor behavior in mice.

  Regulatory peptides 20120110

• Angiotensin receptor blockade attenuates cigarette smoke-induced lung injury and rescues lung architecture in mice.

  The Journal of clinical investigation 20120103

• Losartan enhances the success of myoblast transplantation.

  Cell transplantation 20120101

• Angiotensin II mediates urotensin II expression by hypoxia in cultured cardiac fibroblast.

  European journal of clinical investigation 20120101

• Angiotensin II receptor blocker pretreatment of rats undergoing sudden renal ablation.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120101

• Renin is an angiotensin-independent profibrotic mediator: role in pulmonary fibrosis.

  The European respiratory journal 20120101

• Losartan and amlodipine on myocardial structure and function: a prospective, randomized, clinical trial.

  Diabetic medicine : a journal of the British Diabetic Association 20120101

• Losartan modulates muscular capillary density and reverses thiazide diuretic-exacerbated insulin resistance in fructose-fed rats.

  Hypertension research : official journal of the Japanese Society of Hypertension 20120101

• Cardioprotective effects of low-dose combination therapy with a statin and an angiotensin receptor blocker in a rat myocardial infarction model.

  Journal of cardiology 20120101

• Administration of vitamin E and losartan as prophylaxes in cisplatin-induced nephrotoxicity model in rats.

  Journal of nephrology 20120101

• Angiotensin II-dependent persistent podocyte loss from destabilized glomeruli causes progression of end stage kidney disease.

  Kidney international 20120101

• Mast cells are required for the development of renal fibrosis in the rodent unilateral ureteral obstruction model.

  American journal of physiology. Renal physiology 20120101

• Differential changes of aorta and carotid vasodilation in type 2 diabetic GK and OLETF rats: paradoxical roles of hyperglycemia and insulin.

  Experimental diabetes research 20120101

• Anti-hypertensive therapy and insulin sensitivity: regulation through the microcirculation?

  Hypertension research : official journal of the Japanese Society of Hypertension 20120101

• STK39 variation predicts the ambulatory blood pressure response to losartan in hypertensive men.

  Hypertension research : official journal of the Japanese Society of Hypertension 20120101

• Angiotensin II type 1 receptor antagonist attenuates lung fibrosis in hyperoxia-exposed newborn rats.

  The Journal of pharmacology and experimental therapeutics 20120101

• Effects of antihypertensive drugs on specific harmonic indices of the pulse waveform in normotensive Wistar Kyoto rats.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20120101

• Adding thiazide to a renin-angiotensin blocker improves left ventricular relaxation and improves heart failure in patients with hypertension.

  Hypertension research : official journal of the Japanese Society of Hypertension 20120101

• Interstitial fluid flow and cyclic strain differentially regulate cardiac fibroblast activation via AT1R and TGF-β1.

  Experimental cell research 20120101

• Autophagy as a therapeutic target in diabetic nephropathy.

  Experimental diabetes research 20120101

• Differential effects of strict blood pressure lowering by losartan/hydrochlorothiazide combination therapy and high-dose amlodipine monotherapy on microalbuminuria: the ALPHABET study.

  Journal of the American Society of Hypertension : JASH 20120101

• Angiotensin-(1-7)/Mas axis integrity is required for the expression of object recognition memory.

  Neurobiology of learning and memory 20120101

• The pharmacokinetic-pharmacodynamic assessment of the hypotensive effect after coadministration of losartan and hydrochlorothiazide in spontaneously hypertensive rats.

  Drug metabolism and pharmacokinetics 20120101

• Cost-effectiveness analysis of valsartan versus losartan and the effect of switching.

  Journal of medical economics 20120101

• The effect of the thioether-bridged, stabilized Angiotensin-(1-7) analogue cyclic ang-(1-7) on cardiac remodeling and endothelial function in rats with myocardial infarction.

  International journal of hypertension 20120101

• Telmisartan ameliorates lipopolysaccharide-induced innate immune response through peroxisome proliferator-activated receptor-γ activation in human monocytes.

  Journal of hypertension 20120101

• Effect of a reduction in uric acid on renal outcomes during losartan treatment: a post hoc analysis of the reduction of end points in noninsulin-dependent diabetes mellitus with the Angiotensin II Antagonist Losartan Trial.

  Hypertension (Dallas, Tex. : 1979) 20120101

• Renal microvascular injury in chronic aristolochic acid nephropathy and protective effects of Cozaar.

  Renal failure 20120101

• Biosynthetic pathways and the role of the MAS receptor in the effects of Angiotensin-(1-7) in smooth muscles.

  International journal of hypertension 20120101

• A Novel Cellular Model to Study Angiotensin II AT2 Receptor Function in Breast Cancer Cells.

  International journal of peptides 20120101

• Development of a novel 96-microwell assay with high throughput for determination of olmesartan medoxomil in its tablets.

  Chemistry Central journal 20120101

• Losartan inhibits STAT1 activation and protects human glomerular mesangial cells from angiotensin II induced premature senescence.

  Canadian journal of physiology and pharmacology 20120101

• Angiotensin receptor blocker and N-acetyl cysteine for reduction of proteinuria in patients with type 2 diabetes mellitus.

  Iranian journal of kidney diseases 20120101

• Ramipril-based versus diuretic-based antihypertensive primary treatment in patients with pre-diabetes (ADaPT) study.

  Cardiovascular diabetology 20120101

• The effect of combination treatment with aliskiren and blockers of the renin-angiotensin system on hyperkalaemia and acute kidney injury: systematic review and meta-analysis.

  BMJ (Clinical research ed.) 20120101

• Effects of continuous erythropoietin receptor activator in sepsis-induced acute kidney injury and multi-organ dysfunction.

  PloS one 20120101

• Antihypertensive drugs and risk of incident gout among patients with hypertension: population based case-control study.

  BMJ (Clinical research ed.) 20120101

• Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy.

  PLoS pathogens 20120101

• An economic evaluation of antihypertensive therapies based on clinical trials.

  Clinics (Sao Paulo, Brazil) 20120101

• Effect of switching from telmisartan, valsartan, olmesartan, or losartan to candesartan on morning hypertension.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20120101

• TGFβ signaling and cardiovascular diseases.

  International journal of biological sciences 20120101

• Genotype-phenotype analysis of F-helix mutations at the kinase domain of TGFBR2, including a type 2 Marfan syndrome familial study.

  Molecular vision 20120101

• Preventive pharmacotherapy in type 2 diabetes mellitus.

  Indian journal of endocrinology and metabolism 20120101

• The roles of angiotensin II receptors in the portosystemic collaterals of portal hypertensive and cirrhotic rats.

  Journal of vascular research 20120101

• Losartan reduces trinitrobenzene sulphonic acid-induced colorectal fibrosis in rats.

  Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20120101

• Effect of losartan, an angiotensin II type 1 receptor antagonist on cardiac autonomic functions of rats during acute and chronic inhibition of nitric oxide synthesis.

  Physiological research 20120101

• Pre-treatment with curcumin enhances plasma concentrations of losartan and its metabolite EXP3174 in rats.

  Biological & pharmaceutical bulletin 20120101

• Toxicities effects of pharmaceutical, olive mill and textile wastewaters before and after degradation by Pseudomonas putida mt-2.

  Cancer cell international 20120101

• Kidney disease and youth onset type 2 diabetes: considerations for the general practitioner.

  International journal of pediatrics 20120101

• Protective Role of the ACE2/Ang-(1-9) Axis in Cardiovascular Remodeling.

  International journal of hypertension 20120101

• New cardiovascular and pulmonary therapeutic strategies based on the Angiotensin-converting enzyme 2/angiotensin-(1-7)/mas receptor axis.

  International journal of hypertension 20120101

• Proteinuria: an ignored marker of inflammation and cardiovascular disease in chronic hemodialysis.

  International journal of nephrology and renovascular disease 20120101

• Visual loss after spine surgery.

  Indian journal of orthopaedics 20120101

• Extra-renal elimination of uric acid via intestinal efflux transporter BCRP/ABCG2.

  PloS one 20120101

• Losartan slows pancreatic tumor progression and extends survival of SPARC-null mice by abrogating aberrant TGFβ activation.

  PloS one 20120101

• Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease.

  Journal of neuroinflammation 20120101

• Effects of Losartan vs. Enalapril on the Markers of Metabolic Syndrome.

  Oman medical journal 20120101

• Evidence and consequences of the central role of the kidneys in the pathophysiology of sympathetic hyperactivity.

  Frontiers in physiology 20120101

• Physician and patient predictors of evidence-based prescribing in heart failure: a multilevel study.

  PloS one 20120101

• How full is our antihypertensives pipeline?

  Journal of pharmacology & pharmacotherapeutics 20120101

• Secondary metabolites of Cynodon dactylon as an antagonist to angiotensin II type1 receptor: Novel in silico drug targeting approach for diabetic retinopathy.

  Journal of pharmacology & pharmacotherapeutics 20120101

• Coronary artery disease in Africa and the Middle East.

  Therapeutics and clinical risk management 20120101

• Camurati-Engelmann disease--a rare cause of bone pain.

  Connecticut medicine 20120101

• Variability of NT-proBNP and its relationship with inflammatory status in patients with stable essential hypertension: a 2-year follow-up study.

  PloS one 20120101

• Skeletal muscle apoptotic signaling predicts thigh muscle volume and gait speed in community-dwelling older persons: an exploratory study.

  PloS one 20120101

• NT-proBNP, echocardiographic abnormalities and subclinical coronary artery disease in high risk type 2 diabetic patients.

  Cardiovascular diabetology 20120101

• Is there benefit in optimising heart failure treatment in over-80 year-old patients? (HF-80 study): study protocol for a randomized controlled trial.

  Trials 20120101

• Differential pharmacology and benefit/risk of azilsartan compared to other sartans.

  Vascular health and risk management 20120101

• Genomic research to identify novel pathways in the development of abdominal aortic aneurysm.

  Cardiology research and practice 20120101

• Identification of periostin as a critical marker of progression/reversal of hypertensive nephropathy.

  PloS one 20120101

• Therapeutic options for the treatment of hypertension in children and adolescents.

  Clinical medicine insights. Circulatory, respiratory and pulmonary medicine 20120101

• Delayed mTOR inhibition with low dose of everolimus reduces TGFβ expression, attenuates proteinuria and renal damage in the renal mass reduction model.

  PloS one 20120101

• The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure.

  PloS one 20120101

• Atrial Remodeling in Pregnant Hypertensive Women: Comparison between Chronic and Gestational Hypertension.

  The open cardiovascular medicine journal 20120101

• Effect of combination therapy with the angiotensin receptor blocker losartan plus hydrochlorothiazide on brain perfusion in patients with both hypertension and cerebral hemodynamic impairment due to symptomatic chronic major cerebral artery steno-occlusive disease: a SPECT study.

  Cerebrovascular diseases (Basel, Switzerland) 20120101

• Amiloride enhances antigen specific CTL by faciliting HBV DNA vaccine entry into cells.

  PloS one 20120101

• Brain-derived neurotrophic factor ameliorates brain stem cardiovascular dysregulation during experimental temporal lobe status epilepticus.

  PloS one 20120101

• Does a combination pill of antihypertensive drugs improve medication adherence in Japanese? A randomized controlled trial.

  Circulation journal : official journal of the Japanese Circulation Society 20120101

• Smoking and idiopathic pulmonary fibrosis.

  Pulmonary medicine 20120101

• Quantitative modeling of the physiology of ascites in portal hypertension.

  BMC gastroenterology 20120101

• Nebivolol: impact on cardiac and endothelial function and clinical utility.

  Vascular health and risk management 20120101

• [Investigate the effects of compound radix notoginseng on renal interstitial fibrosis and kidney-targeting treatment].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20120101

• New treatment options in the management of hypertension: appraising the potential role of azilsartan medoxomil.

  Integrated blood pressure control 20120101

• The diabetic heart: too sweet for its own good?

  Cardiology research and practice 20120101

• Overexpression of urinary N-domain ACE in chronic kidney dysfunction in Wistar rats.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20120101

• Insulin resistance promotes early atherosclerosis via increased proinflammatory proteins and oxidative stress in fructose-fed ApoE-KO mice.

  Experimental diabetes research 20120101

• Choice of generic antihypertensive drugs for the primary prevention of cardiovascular disease--a cost-effectiveness analysis.

  BMC cardiovascular disorders 20120101

• High plasma uric acid concentration: causes and consequences.

  Diabetology & metabolic syndrome 20120101

• Mineralocorticoid Receptor Blocker Protects against Podocyte-Dependent Glomerulosclerosis.

  Nephron extra 20120101

• Inflammation aggravates disease severity in Marfan syndrome patients.

  PloS one 20120101

• Uremic toxins induce kidney fibrosis by activating intrarenal renin-angiotensin-aldosterone system associated epithelial-to-mesenchymal transition.

  PloS one 20120101

• Increased fibrosis and interstitial fluid pressure in two different types of syngeneic murine carcinoma grown in integrin β3-subunit deficient mice.

  PloS one 20120101

• Comparative effectiveness of antihypertensive medication for primary prevention of cardiovascular disease: systematic review and multiple treatments meta-analysis.

  BMC medicine 20120101

• Effects of combined endothelin A receptor and renin-angiotensin system blockade on the course of end-organ damage in 5/6 nephrectomized Ren-2 hypertensive rats.

  Kidney & blood pressure research 20120101

• The effect of antihypertensive drugs on endothelial function as assessed by flow-mediated vasodilation in hypertensive patients.

  International journal of vascular medicine 20120101

• What is a preferred angiotensin II receptor blocker-based combination therapy for blood pressure control in hypertensive patients with diabetic and non-diabetic renal impairment?

  Cardiovascular diabetology 20120101

• Design and evaluation of patches for transdermal delivery of losartan potassium.

  PDA journal of pharmaceutical science and technology 20120101

• Angiotensinogen gene transcription in pulmonary fibrosis.

  International journal of peptides 20120101

• Influence of Angiotensin II Subtype 2 Receptor (AT(2)R) Antagonist, PD123319, on Cardiovascular Remodelling of Aged Spontaneously Hypertensive Rats during Chronic Angiotensin II Subtype 1 Receptor (AT(1)R) Blockade.

  International journal of hypertension 20120101

• Novel intriguing strategies attenuating to sarcopenia.

  Journal of aging research 20120101

• Glucoregulatory consequences and cardiorespiratory parameters in rats exposed to chronic-intermittent hypoxia: effects of the duration of exposure and losartan.

  Frontiers in neurology 20120101

• Angiotensin converting enzyme 2, Angiotensin-(1-7), and receptor MAS axis in the kidney.

  International journal of hypertension 20120101

• Reactive Oxygen Species Modulation of Na/K-ATPase Regulates Fibrosis and Renal Proximal Tubular Sodium Handling.

  International journal of nephrology 20120101

• Molecular mechanisms of preeclampsia.

  Journal of pregnancy 20120101

• Renin angiotensin system: A novel target for migraine prophylaxis.

  Indian journal of pharmacology 20120101

• Unilateral ureteric obstruction: Role of renin angiotensin system blockade on renal recovery: An experimental study.

  Journal of Indian Association of Pediatric Surgeons 20120101

• Post-weaning protein malnutrition increases blood pressure and induces endothelial dysfunctions in rats.

  PloS one 20120101

• Electrocardiographic left ventricular hypertrophy and outcome in hemodialysis patients.

  PloS one 20120101

• Angiotensin receptor blockers and risk of cancer: cohort study among people receiving antihypertensive drugs in UK General Practice Research Database.

  BMJ (Clinical research ed.) 20120101

• Long-term effects of aliskiren on blood pressure and the renin-angiotensin-aldosterone system in hypertensive hemodialysis patients.

  International journal of nephrology and renovascular disease 20120101

• Emerging drug combinations to optimize renovascular protection and blood pressure goals.

  International journal of nephrology and renovascular disease 20120101

• Effects of restricted fructose access on body weight and blood pressure circadian rhythms.

  Experimental diabetes research 20120101

• Angiotensin-Converting Enzyme 2 (ACE2) Is a Key Modulator of the Renin Angiotensin System in Health and Disease.

  International journal of peptides 20120101

• Angiotensin II facilitates breast cancer cell migration and metastasis.

  PloS one 20120101

• Connexins and diabetes.

  Cardiology research and practice 20120101

• Renin-Angiotensin system hyperactivation can induce inflammation and retinal neural dysfunction.

  International journal of inflammation 20120101

• Promyelocytic leukemia zinc finger protein activates GATA4 transcription and mediates cardiac hypertrophic signaling from angiotensin II receptor 2.

  PloS one 20120101

• Activation of thiazide-sensitive co-transport by angiotensin II in the cyp1a1-Ren2 hypertensive rat.

  PloS one 20120101

• Cardiovascular magnetic resonance in systemic hypertension.

  Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20120101

• Mechanisms and biomarkers of apoptosis in liver disease and fibrosis.

  International journal of hepatology 20120101

• Simultaneous Analysis of Losartan Potassium, Amlodipine Besylate, and Hydrochlorothiazide in Bulk and in Tablets by High-Performance Thin Layer Chromatography with UV-Absorption Densitometry.

  Journal of analytical methods in chemistry 20120101

• Different stability-indicating chromatographic techniques for the determination of netobimin.

  Journal of analytical methods in chemistry 20120101

• Sensitive spectrophotometric determination of atenolol in pharmaceutical formulations using bromate-bromide mixture as an eco-friendly brominating agent.

  Journal of analytical methods in chemistry 20120101

• Glaucomatous optic nerve head alterations in patients with chronic heart failure.

  Clinical ophthalmology (Auckland, N.Z.) 20120101

• Anxiolytic-like effect of losartan injected into amygdala of the acutely stressed rats.

  Pharmacological reports : PR 20120101

• The prevalence of immunologic injury in renal allograft recipients with de novo proteinuria.

  PloS one 20120101

• Hypertension and type 2 diabetes: a cross-sectional study in Morocco (EPIDIAM Study).

  The Pan African medical journal 20120101

• Angiotensin II induces angiogenic factors production partly via AT1/JAK2/STAT3/SOCS3 signaling pathway in MHCC97H cells.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

• The role of apelin on the alleviative effect of Angiotensin receptor blocker in unilateral ureteral obstruction-induced renal fibrosis.

  Nephron extra 20120101

• Responses to dehydration in the one-humped camel and effects of blocking the renin-angiotensin system.

  PloS one 20120101

• Sympathetic activation and baroreflex function during intradialytic hypertensive episodes.

  PloS one 20120101

• Can losartan and blood pressure control peri arteriovenous fistula creation ameliorate the early associated left ventricular hypertrophic response a randomised placebo controlled trial.

  BMC research notes 20120101

• Telmisartan directly ameliorates the neuronal inflammatory response to IL-1β partly through the JNK/c-Jun and NADPH oxidase pathways.

  Journal of neuroinflammation 20120101

• The involvement of angiotensin type 1 and type 2 receptors in estrogen-induced cell proliferation and vascular endothelial growth factor expression in the rat anterior pituitary.

  TheScientificWorldJournal 20120101

• Urinary markers of glomerular injury in diabetic nephropathy.

  International journal of nephrology 20120101

• Critical evaluation of the efficacy and tolerability of azilsartan.

  Vascular health and risk management 20120101

• Use of carvedilol in hypertension: an update.

  Vascular health and risk management 20120101

• Clinical efficacy and safety of losartan/hydrochlorothiazide combination therapy.

  Internal medicine (Tokyo, Japan) 20120101

• Efficacy and safety of the losartan-hydrochlorothiazide combination tablet in patients with hypertension uncontrolled by angiotensin II receptor antagonist therapy: the Aichi Research on Combination therapy for Hypertension (ARCH) Study.

  Internal medicine (Tokyo, Japan) 20120101

• Antioxidants in kidney diseases: the impact of bardoxolone methyl.

  International journal of nephrology 20120101

• Activation of EGFR/ERBB2 via pathways involving ERK1/2, P38 MAPK, AKT and FOXO enhances recovery of diabetic hearts from ischemia-reperfusion injury.

  PloS one 20120101

• Myocardial contractile dysfunction induced by ovariectomy requires AT1 receptor activation in female rats.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

• Myocardial autophagy after severe burn in rats.

  PloS one 20120101

• The role of angiotensin II receptor 1 (AT1) blockade in cisplatin-induced nephrotoxicity in rats: gender-related differences.

  Renal failure 20120101

• Randomized Polypill crossover trial in people aged 50 and over.

  PloS one 20120101

• Combination of antihypertensive therapy in the elderly, multicenter investigation (CAMUI) trial.

  International heart journal 20120101

• (Pro)renin receptor triggers distinct angiotensin II-independent extracellular matrix remodeling and deterioration of cardiac function.

  PloS one 20120101

• A low-dose atorvastatin and losartan combination directly improves aortic ring relaxation and diminishes ischaemic-reperfusion injury in isolated rat hearts.

  Medical science monitor : international medical journal of experimental and clinical research 20120101

• Effects of combined antihypertensive therapy with losartan/hydrochlorothiazide on uric acid metabolism.

  Internal medicine (Tokyo, Japan) 20120101

• Losartan alleviates renal fibrosis by down-regulating HIF-1α and up-regulating MMP-9/TIMP-1 in rats with 5/6 nephrectomy.

  Renal failure 20120101

• Adding thiazide to a rennin-angiotensin blocker regimen to improve left ventricular relaxation in diabetes and nondiabetes patients with hypertension.

  Drug design, development and therapy 20120101

• Interaction of TNF with angiotensin II contributes to mitochondrial oxidative stress and cardiac damage in rats.

  PloS one 20120101

• Vitamin E, Vitamin C, or Losartan Is Not Nephroprotectant against Cisplatin-Induced Nephrotoxicity in Presence of Estrogen in Ovariectomized Rat Model.

  International journal of nephrology 20120101

• Effect of angiotensin II type 1 receptor blocker on osteoporotic rat femurs.

  Pharmacological reports : PR 20120101

• Losartan-induced coronary artery spasm.

  BMJ case reports 20120101

• [Effectiveness and safety of losartan and its combination with hydrochlorothiazide in patients with hypertension: in result study].

  Kardiologiia 20120101

• Effect of methanolic fraction of Kalanchoe crenata on metabolic parameters in adriamycin-induced renal impairment in rats.

  Indian journal of pharmacology 20120101

• Angiotensin II protects primary rat hepatocytes against bile salt-induced apoptosis.

  PloS one 20120101

• Hypotensive effect of atorvastatin in hypertensive patients: the association among flow-mediated dilation, oxidative stress and endothelial dysfunction.

  Archives of medical science : AMS 20111231

• IMproving the imPlemEntation of cuRrent guidelines for the mAnagement of major coronary hearT disease rIsk factors by multifactorial interVEntion. The IMPERATIVE renal analysis.

  Archives of medical science : AMS 20111231

• Lipids, blood pressure, kidney - what was new in 2011?

  Archives of medical science : AMS 20111231

• Synthesis of angiotensin II receptor blockers by means of a catalytic system for C-H activation.

  The Journal of organic chemistry 20111216

• [Treatment of gout].

  La Revue de medecine interne 20111201

• Chronic angiotensin II infusion modulates angiotensin II type I receptor expression in the subfornical organ and the rostral ventrolateral medulla in hypertensive rats.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20111201

• Change in left ventricular geometry during antihypertensive treatment in children with primary hypertension.

  Pediatric nephrology (Berlin, Germany) 20111201

• Angiotensin II downregulates catalase expression and activity in vascular adventitial fibroblasts through an AT1R/ERK1/2-dependent pathway.

  Molecular and cellular biochemistry 20111201

• Modifying prescribing behaviour of angiotensin receptor blockers by selectively rescinding managerial prior authorization requirements for losartan.

  British journal of clinical pharmacology 20111201

• Telomere length and cardiovascular risk in hypertensive patients with left ventricular hypertrophy: the LIFE study.

  Journal of human hypertension 20111201

• Proinflammatory role of angiotensin II in a rat nephrosis model induced by adriamycin.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20111201

• Intracrine action of angiotensin II in the intact ventricle of the failing heart: angiotensin II changes cardiac excitability from within.

  Molecular and cellular biochemistry 20111201

• Suppression of aldosterone mediates regression of left ventricular hypertrophy in patients with hypertension.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20111201

• Targeting the renin-angiotensin system: potential beneficial effects of the angiotensin II receptor blockers in patients with nonalcoholic steatohepatitis.

  Hepatology (Baltimore, Md.) 20111201

• Liver lipid content is reduced in rat given 7-day administration of angiotensin II.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20111201

• Reduction of circulating superoxide dismutase activity in type 2 diabetic patients with microalbuminuria and its modulation by telmisartan therapy.

  Hypertension research : official journal of the Japanese Society of Hypertension 20111201

• Antihypertensive treatment using an angiotensin receptor blocker and a thiazide diuretic improves patients' quality of life: the Saga Challenge Antihypertensive Study (S-CATS).

  Hypertension research : official journal of the Japanese Society of Hypertension 20111201

• Bitter melon extracts in diabetic and normal rats favorably influence blood glucose and blood pressure regulation.

  Journal of medicinal food 20111201

• A two-stage approach to the treatment of hyperuricemia in gout: the 'dirty dish' hypothesis.

  Arthritis and rheumatism 20111201

• The loss of muscle mass and sarcopenia: non hormonal intervention.

  Experimental gerontology 20111201

• Losartan improves aortic endothelium-dependent relaxation via proline-rich tyrosine kinase 2/Src/Akt pathway in type 2 diabetic Goto-Kakizaki rats.

  American journal of physiology. Heart and circulatory physiology 20111201

• Angiotensin II type 1 receptor, but no type 2 receptor, interferes with the insulin-induced nitric oxide production in HUVECs.

  Atherosclerosis 20111201

• Angiotensin II-NADPH oxidase-derived superoxide mediates diabetes-attenuated cell excitability of aortic baroreceptor neurons.

  American journal of physiology. Cell physiology 20111201

• Prevention and treatment of Schistosoma mansoni-induced liver fibrosis in mice.

  Inflammopharmacology 20111201

• ETA and ETB receptors are expressed in vascular adventitial fibroblasts.

  American journal of physiology. Heart and circulatory physiology 20111201

• Chronic antagonism of the mineralocorticoid receptor ameliorates hypertension and end organ damage in a rodent model of salt-sensitive hypertension.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20111201

• The impact of antiproteinuric therapy on the prothrombotic state in patients with overt proteinuria.

  Journal of thrombosis and haemostasis : JTH 20111201

• Effects of captopril and angiotensin II receptor blockers (AT1, AT2) on myocardial ischemia-reperfusion induced infarct size.

  Cytokine 20111201

• Effects of olmesartan on renal and cardiovascular outcomes in type 2 diabetes with overt nephropathy: a multicentre, randomised, placebo-controlled study.

  Diabetologia 20111201

• Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist.

  The Journal of pathology 20111201

• Pharmacogenomic strain differences in cardiovascular sensitivity to propofol.

  Anesthesiology 20111201

• Renin-angiotensin system inhibitors reduce the progression of mesangioproliferative glomerulonephritis: 10 year follow-up.

  European journal of internal medicine 20111201

• Effects of losartan/hydrochlorothiazide on serum uric acid levels and blood pressure in hypertensive patients.

  Nucleosides, nucleotides & nucleic acids 20111201

• Cordyceps cicadae extracts ameliorate renal malfunction in a remnant kidney model.

  Journal of Zhejiang University. Science. B 20111201

• Comparative efficacy and safety profile of amlodipine 5 mg/losartan 50 mg fixed-dose combination and amlodipine 10 mg monotherapy in hypertensive patients who respond poorly to amlodipine 5 mg monotherapy: an 8-week, multicenter, randomized, double-blind phase III noninferiority study.

  Clinical therapeutics 20111201

• Diffuse large cell lymphoma presenting as a sacral mass and lupus anticoagulant.

  The Yale journal of biology and medicine 20111201

• Medical reversal: why we must raise the bar before adopting new technologies.

  The Yale journal of biology and medicine 20111201

• One size may not fit all: anti-aging therapies and sarcopenia.

  Aging 20111201

• Protective measures against ultrafiltration failure in peritoneal dialysis patients.

  Clinics (Sao Paulo, Brazil) 20111201

• Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

  PLoS computational biology 20111201

• Sign of decreased coronary blood flow from ST depression and PVCs during a left lower lobectomy of the lung in a patient with a left internal mammary arterial bypass graft.

  Korean journal of anesthesiology 20111201

• Very Late Stent Thrombosis due to Neointimal Rupture After Paclitaxel-Eluting Stent Implantation.

  Korean circulation journal 20111201

• NADPH oxidase mediated oxidative stress in hepatic fibrogenesis.

  The Korean journal of hepatology 20111201

• Fluorofenidone suppresses epithelial-mesenchymal transition and the expression of connective tissue growth factor via inhibiting TGF-beta/Smads signaling in human proximal tubular epithelial cells.

  Die Pharmazie 20111201

• Efficacy and safety of early versus late titration of fixed-dose irbesartan/hydrochlorothiazide: ACTUAL study.

  Blood pressure. Supplement 20111201

• Novel pharmacological strategies to prevent aortic complications in Marfan syndrome.

  Journal of geriatric cardiology : JGC 20111201

• Structural characteristics of renal glomerular system in ISIAH rats under conditions of chronic stress and preventive hypotensive drug therapy.

  Bulletin of experimental biology and medicine 20111201

• Natriorexigenic effect of baclofen is reduced by AT₁ receptor blockade in the lateral parabrachial nucleus.

  Brain research bulletin 20111125

• Importance of central AT₁ receptors for sodium intake induced by GABAergic activation of the lateral parabrachial nucleus.

  Neuroscience 20111124

• Increased oxidative stress, the renin-angiotensin system, and sympathetic overactivation induce hypertension in kidney androgen-regulated protein transgenic mice.

  Free radical biology & medicine 20111115

• Losartan abolishes oxidative stress induced by intermittent hypoxia in humans.

  The Journal of physiology 20111115

• Pharmacologic inhibition of the renin-angiotensin system did not attenuate hepatic toxicity induced by carbon tetrachloride in rats.

  Human & experimental toxicology 20111101

• [Fibrillary nonamyloid glomerulonephritis: a rare etiology of nephrotic syndrome].

  Nephrologie & therapeutique 20111101

• Angiotensin II causes endothelial dysfunction via the GRK2/Akt/eNOS pathway in aortas from a murine type 2 diabetic model.

  Pharmacological research 20111101

• High serum potassium levels after using losartan can reflect more severe renal disease.

  Diabetologia 20111101

• Enalapril treatment discloses an early role of angiotensin II in inflammation- and oxidative stress-related muscle damage in dystrophic mdx mice.

  Pharmacological research 20111101

• Transactivation of epidermal growth factor receptor by enhanced levels of endogenous angiotensin II contributes to the overexpression of Giα proteins in vascular smooth muscle cells from SHR.

  Cellular signalling 20111101

• Rosiglitazone versus rosiglitazone and metformin versus rosiglitazone and losartan in the treatment of nonalcoholic steatohepatitis in humans: a 12-month randomized, prospective, open- label trial.

  Hepatology (Baltimore, Md.) 20111101

• Electromechanical effects of the direct renin inhibitor (aliskiren) on the pulmonary vein and atrium.

  Basic research in cardiology 20111101

• Rationale and current perspective for early rhythm control therapy in atrial fibrillation.

  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20111101

• Fetopathy probably associated to self-medication with a blocker of the renin-angiotensin system.

  Archives of gynecology and obstetrics 20111101

• Mechanisms mediating sodium-induced pressor responses in the PVN of Dahl rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20111101

• Effects of telmisartan and losartan on cardiovascular protection in Japanese hypertensive patients.

  Hypertension research : official journal of the Japanese Society of Hypertension 20111101

• Des-aspartate-angiotensin-I and angiotensin IV improve glucose tolerance and insulin signalling in diet-induced hyperglycaemic mice.

  Biochemical pharmacology 20111101

• Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis.

  Kidney international 20111101

• The central mechanism underlying hypertension: a review of the roles of sodium ions, epithelial sodium channels, the renin-angiotensin-aldosterone system, oxidative stress and endogenous digitalis in the brain.

  Hypertension research : official journal of the Japanese Society of Hypertension 20111101

• Brain AT1 receptor activates the sympathetic nervous system through toll-like receptor 4 in mice with heart failure.

  Journal of cardiovascular pharmacology 20111101

• Decreased nNOS in the PVN leads to increased sympathoexcitation in chronic heart failure: role for CAPON and Ang II.

  Cardiovascular research 20111101

• Mechanisms underlying altered extracellular nucleotide-induced contractions in mesenteric arteries from rats in later-stage type 2 diabetes: effect of ANG II type 1 receptor antagonism.

  American journal of physiology. Heart and circulatory physiology 20111101

• In vivo key role of reactive oxygen species and NHE-1 activation in determining excessive cardiac hypertrophy.

  Pflugers Archiv : European journal of physiology 20111101

• Angiotensin II receptors modulate muscle microvascular and metabolic responses to insulin in vivo.

  Diabetes 20111101

• Blood pressure and renal hemodynamic responses to acute angiotensin II infusion are enhanced in a female mouse model of systemic lupus erythematosus.

  American journal of physiology. Regulatory, integrative and comparative physiology 20111101

• Renin-angiotensin and sympathetic nervous system contribution to high blood pressure in Schlager mice.

  Journal of hypertension 20111101

• Therapeutic perspectives in hypertension: novel means for renin-angiotensin-aldosterone system modulation and emerging device-based approaches.

  European heart journal 20111101

• Should combination therapy be the paradigm for future nonalcoholic steatohepatitis clinical trials?

  Hepatology (Baltimore, Md.) 20111101

• Regulation of angiotensin-(1-7) and angiotensin II type 1 receptor by telmisartan and losartan in adriamycin-induced rat heart failure.

  Acta pharmacologica Sinica 20111101

• Blood pressure outcomes in patients receiving angiotensin II receptor blockers in primary care: a comparative effectiveness analysis from electronic medical record data.

  Journal of clinical hypertension (Greenwich, Conn.) 20111101

• Spontaneous remission of post-transplant recurrent focal and segmental glomerulosclerosis.

  Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20111101

• A pilot study on the effect of telmisartan & ramipril on 24 h blood pressure profile & dipping pattern in type 1 diabetes patients with nephropathy.

  The Indian journal of medical research 20111101

• Experimental depression induces renal oxidative stress in rats.

  Physiology & behavior 20111024

• 24-Hour ambulatory blood pressure control with triple-therapy amlodipine, valsartan and hydrochlorothiazide in patients with moderate to severe hypertension.

  Journal of human hypertension 20111001

• Anabolic steroid associated to physical training induces deleterious cardiac effects.

  Medicine and science in sports and exercise 20111001

• Do genetic variants of the Renin-Angiotensin system predict blood pressure response to Renin-Angiotensin system-blocking drugs?: a systematic review of pharmacogenomics in the Renin-Angiotensin system.

  Current hypertension reports 20111001

• Contributions of ACE and mast cell chymase to endogenous angiotensin II generation and leucocyte recruitment in vivo.

  Cardiovascular research 20111001

• Inflammatory cytokines in paraventricular nucleus modulate sympathetic activity and cardiac sympathetic afferent reflex in rats.

  Acta physiologica (Oxford, England) 20111001

• Angiotensin II evokes sensory long-term facilitation of the carotid body via NADPH oxidase.

  Journal of applied physiology (Bethesda, Md. : 1985) 20111001

• Effect of losartan on proteinuria and urinary angiotensinogen excretion in non-diabetic patients with chronic kidney disease.

  Postgraduate medical journal 20111001

• Potential antifibrotic effects of AT1 receptor antagonist, losartan, and/or praziquantel on acute and chronic experimental liver fibrosis induced by Schistosoma mansoni.

  Clinical and experimental pharmacology & physiology 20111001

• The impact of hepatic uptake on the pharmacokinetics of organic anions.

  Drug metabolism and disposition: the biological fate of chemicals 20111001

• Angiotensin III stimulates ERK1/2 mitogen-activated protein kinases and astrocyte growth in cultured rat astrocytes.

  Neuropeptides 20111001

• Acute and chronic angiotensin-(1-7) restores vasodilation and reduces oxidative stress in mesenteric arteries of salt-fed rats.

  American journal of physiology. Heart and circulatory physiology 20111001

• Frequency of CYP2C9 alleles in Koreans and their effects on losartan pharmacokinetics.

  Acta pharmacologica Sinica 20111001

• Management of gout in the older adult.

  The American journal of geriatric pharmacotherapy 20111001

• The effect of amlodipine besylate, losartan potassium, olmesartan medoxomil, and other antihypertensives on central aortic blood pressure and biomarkers of vascular function.

  Therapeutic advances in cardiovascular disease 20111001

• Combination of fluvastatin and losartan relieves atherosclerosis and macrophage infiltration in atherosclerotic plaques in rabbits.

  Acta pharmacologica Sinica 20111001

• Vascular mechanisms involved in angiotensin II-induced venoconstriction in hypertensive rats.

  Peptides 20111001

• ACEI and ARB combination therapy in patients with macroalbuminuric diabetic nephropathy and low socioeconomic level: a double-blind randomized clinical trial.

  Clinical nephrology 20111001

• To study the efficacy of Losartan on urinary uric acid excretion in Thiazide induced hyperuricemic and hypertensive patients.

  Pakistan journal of pharmaceutical sciences 20111001

• Pharmacotherapy review of chronic pediatric hypertension.

  Clinical therapeutics 20111001

• Effects of telmisartan on insulin resistance and visceral fat distribution in Chinese hypertensive patients with obesity.

  Saudi medical journal 20111001

• [Effects of Chinese herbal medicine Yiqi Zengmin formula on expression of glucose transporter 4 in skeletal muscle in type 2 diabetic rats].

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20111001

• Critical evaluation of the optimal medical therapy in the cardiac resynchronization therapy candidates--single centre experience.

  Vnitrni lekarstvi 20111001

• Telmisartan versus valsartan in patients with hypertension: effects on cardiovascular, metabolic, and inflammatory parameters.

  Korean circulation journal 20111001

• Management of diabetic hypertensives.

  Indian journal of endocrinology and metabolism 20111001

• Aliskiren prevents and ameliorates metabolic syndrome in fructose-fed rats.

  Archives of medical science : AMS 20111001

• Irregular electrical activation of intrinsic cardiac adrenergic cells increases catecholamine-synthesizing enzymes.

  Biochemical and biophysical research communications 20110930

• [Young patient with mild hypertension: angiotensin inhibitor or beta blocker?].

  MMW Fortschritte der Medizin 20110922

• Switching control of sympathetic activity from forebrain to hindbrain in chronic dehydration.

  The Journal of physiology 20110915

• Pravastatin reduces Marfan aortic dilation.

  Circulation 20110913

• [Angioedema due to losartan].

  Medicina clinica 20110910

• Role of perivascular adipose tissue-derived methyl palmitate in vascular tone regulation and pathogenesis of hypertension.

  Circulation 20110906

• Drug therapy of heart failure: an immunologic view.

  American journal of therapeutics 20110901

• Changes in metabolic profile and population of skeletal muscle fibers of mice overexpressing calsequestrin: influence of losartan.

  Acta histochemica 20110901

• Losartan potassium/hydrochlorothiazide (Preminent®) and hyponatremia: case series of 40 patients.

  Human & experimental toxicology 20110901

• Effect of hypoxia in mice mesenteric arteries surrounded by adipose tissue.

  Acta physiologica (Oxford, England) 20110901

• Characterization of a stable, hypertensive rat model suitable for the consecutive evaluation of human renin inhibitors.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20110901

• Losartan protects mesenteric arteries from ROS-associated decrease in myogenic constriction following 5/6 nephrectomy.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20110901

• Use of enterally delivered angiotensin II type Ia receptor antagonists to reduce the severity of colitis.

  Digestive diseases and sciences 20110901

• A systematic review and meta-analysis of candesartan and losartan in the management of essential hypertension.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20110901

• Cognitive enhancement following acute losartan in normotensive young adults.

  Psychopharmacology 20110901

• NADPH oxidase-dependent formation of reactive oxygen species contributes to angiotensin II-induced epithelial-mesenchymal transition in rat peritoneal mesothelial cells.

  International journal of molecular medicine 20110901

• Intracellular angiotensin II activates rat myometrium.

  American journal of physiology. Cell physiology 20110901

• Effects of uremic toxins on transport and metabolism of different biopharmaceutics drug disposition classification system xenobiotics.

  Journal of pharmaceutical sciences 20110901

• Both AT₁ and AT₂ receptors mediate proliferation and migration of porcine vascular smooth muscle cells.

  American journal of physiology. Heart and circulatory physiology 20110901

• Effects of losartan, in monotherapy or in association with hydrochlorothiazide, in chronic nephropathy resulting from losartan treatment during lactation.

  American journal of physiology. Renal physiology 20110901

• The clinical value of apex beat and electrocardiography for the detection of left ventricular hypertrophy from the standpoint of the distance factors from the heart to the chest wall: a multislice CT study.

  Hypertension research : official journal of the Japanese Society of Hypertension 20110901

• Phosphoproteomic analysis of AT1 receptor-mediated signaling responses in proximal tubules of angiotensin II-induced hypertensive rats.

  Kidney international 20110901

• Impact of systemically active neurohumoral factors on the erectile response of the rat.

  The journal of sexual medicine 20110901

• 1-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-pyrrolidine-2-carboxamide: investigation of structural variations.

  Archiv der Pharmazie 20110901

• Long-term clinical and economic outcomes associated with angiotensin II receptor blocker use in hypertensive patients.

  Current medical research and opinion 20110901

• Glomerular expression of kidney injury molecule-1 and podocytopenia in diabetic glomerulopathy.

  American journal of nephrology 20110901

• Retrospective analysis of real-world efficacy of angiotensin receptor blockers versus other classes of antihypertensive agents in blood pressure management.

  Clinical therapeutics 20110901

• Compliance, persistence, and switching patterns for ACE inhibitors and ARBs.

  The American journal of managed care 20110901

• Interaction between sympathetic nervous system and renin angiotensin system on MMPs expression in juvenile rat aorta.

  General physiology and biophysics 20110901

• Acromegaly with no pituitary adenoma and no evidence of ectopic source.

  Indian journal of endocrinology and metabolism 20110901

• Subclinical Myocardial Dysfunction in Metabolic Syndrome Patients without Hypertension.

  Journal of cardiovascular ultrasound 20110901

• Hypertensive heart failure associated with middle aortic syndrome reversed dramatically by endovascular management.

  Journal of cardiovascular ultrasound 20110901

• AT1 receptors activation enhances the expression of MMP-2, MMP-13 and VEGF but not MMP-9 in B16F10 melanoma cells.

  Pakistan journal of biological sciences : PJBS 20110901

• Preparation and characterization of pH-independent sustained release tablet containing solid dispersion granules of a poorly water-soluble drug.

  International journal of pharmaceutics 20110830

• Angiotensin II does not directly affect Aβ secretion or β-/γ-secretase activity via activation of angiotensin II type 1 receptor.

  Neuroscience letters 20110815

• Cardiovascular MRI in clinical trials: expanded applications through novel surrogate endpoints.

  Heart (British Cardiac Society) 20110815

• The prognostic value of circulating markers of collagen turnover after acute myocardial infarction.

  International journal of cardiology 20110804

• Diabetes: Lowering serum uric acid levels to prevent kidney failure.

  Nature reviews. Nephrology 20110802

• Protective actions of des-aspartate-angiotensin I in mice model of CEES-induced lung intoxication.

  Journal of applied toxicology : JAT 20110801

• Efficacy and safety of losartan in children with Alport syndrome--results from a subgroup analysis of a prospective, randomized, placebo- or amlodipine-controlled trial.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110801

• Effect of atorvastatin on CYP2C9 metabolic activity as measured by the formation rate of losartan metabolite in hypercholesterolaemic patients.

  Basic & clinical pharmacology & toxicology 20110801

• An acute fall in estimated glomerular filtration rate during treatment with losartan predicts a slower decrease in long-term renal function.

  Kidney international 20110801

• Clinical relevance of liquid chromatography tandem mass spectrometry as an analytical method in microdose clinical studies.

  Pharmaceutical research 20110801

• A case of serious laryngeal edema unpredictably detected during laryngoscopy for orotracheal intubation following induction of anesthesia.

  Journal of anesthesia 20110801

• Effect of diet, enalapril, or losartan in post-diarrheal hemolytic uremic syndrome nephropathy.

  Pediatric nephrology (Berlin, Germany) 20110801

• Fetal uninephrectomy in male sheep alters the systemic and renal responses to angiotensin II infusion and AT1R blockade.

  American journal of physiology. Renal physiology 20110801

• Angiotensin II induces microtubule reorganization mediated by a deacetylase SIRT2 in endothelial cells.

  Hypertension research : official journal of the Japanese Society of Hypertension 20110801

• Angiotensin receptor blockade and risk of cancer in type 2 diabetes mellitus: a nationwide case-control study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110801

• Comparison of angiotensin converting enzyme inhibitors and angiotensin II type 1 receptor blockade for the prevention of premalignant changes in the liver.

  Life sciences 20110801

• Benefits of Renin-Angiotensin blockade on retinopathy in type 1 diabetes vary with glycemic control.

  Diabetes care 20110801

• In-treatment stroke volume predicts cardiovascular risk in hypertension.

  Journal of hypertension 20110801

• Inhibition of soluble epoxide hydrolase improves the impaired pressure-natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ damage in Cyp1a1-Ren-2 transgenic rats.

  Journal of hypertension 20110801

• Acute fall in glomerular filtration rate with renin-angiotensin system inhibition: a biomeasure of therapeutic success?

  Kidney international 20110801

• Comments on systematic review of clinical- and cost-effectiveness of candesartan and losartan in hypertension and heart failure.

  International journal of clinical practice 20110801

• Effects of antiproteinuric intervention on elevated connective tissue growth factor (CTGF/CCN-2) plasma and urine levels in nondiabetic nephropathy.

  Clinical journal of the American Society of Nephrology : CJASN 20110801

• Combination angiotensin-receptor blocker (ARB)/calcium channel blocker with HCTZ vs the maximal recommended dose of an ARB with HCTZ in patients with stage 2 hypertension: the exforge as compared to losartan treatment in stage 2 systolic hypertension (EXALT) study.

  Journal of clinical hypertension (Greenwich, Conn.) 20110801

• Influence of demand-side measures to enhance renin-angiotensin prescribing efficiency in Europe: implications for the future.

  Expert review of pharmacoeconomics & outcomes research 20110801

• Meeting report: American Aging Association 40th Annual Meeting, Raleigh, North Carolina, June 3-6, 2011.

  Rejuvenation research 20110801

• [Effect of losartan on renal expression of monocyte chemoattractant protein-1 and transforming growth factor-β(1) in rats after unilateral ureteral obstruction].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110801

• Rosuvastatin prevents proteinuria and renal inflammation in nitric oxide-deficient rats.

  Clinics (Sao Paulo, Brazil) 20110801

• A case of metastatic renal cell carcinoma to thyroid gland.

  Chonnam medical journal 20110801

• AT₁ receptor blockade in the lateral parabrachial nucleus reduces the effects of muscimol on sodium intake.

  Brain research 20110727

• Hemin decreases cardiac oxidative stress and fibrosis in a rat model of systemic hypertension via PI3K/Akt signalling.

  Cardiovascular research 20110715

• Telmisartan protects against diabetic vascular complications in a mouse model of obesity and type 2 diabetes, partially through peroxisome proliferator activated receptor-γ-dependent activity.

  Biochemical and biophysical research communications 20110708

• Primary stroke prevention and hypertension treatment: which is the first-line strategy?

  Neurology international 20110705

• High level of proteinuria during treatment with renin-angiotensin inhibitors is a strong predictor of renal outcome in nondiabetic kidney disease.

  Journal of clinical pharmacology 20110701

• Preventing the aortic complications of Marfan syndrome: a case-example of translational genomic medicine.

  British journal of clinical pharmacology 20110701

• Angiotensin II increases periostin expression via Ras/p38 MAPK/CREB and ERK1/2/TGF-β1 pathways in cardiac fibroblasts.

  Cardiovascular research 20110701

• Inhibition of NF-κB-induced inflammatory responses by angiotensin II antagonists in aged rat kidney.

  Experimental gerontology 20110701

• Mechanism underlying the efficacy of combination therapy with losartan and hydrochlorothiazide in rats with salt-sensitive hypertension.

  Hypertension research : official journal of the Japanese Society of Hypertension 20110701

• Angiotensin II plays a critical role in diabetic pulmonary fibrosis most likely via activation of NADPH oxidase-mediated nitrosative damage.

  American journal of physiology. Endocrinology and metabolism 20110701

• The role of the renin-angiotensin system in thoracic aortic aneurysms: clinical implications.

  Pharmacology & therapeutics 20110701

• High salt intake abolishes AT(2)-mediated vasodilation of pial arterioles in rats.

  Journal of hypertension 20110701

• Characterization of the genomic structure and function of regions influencing renin and angiogenesis in the SS rat.

  Physiological genomics 20110701

• Altered regulation of the rostral ventrolateral medulla in hypertensive obese Zucker rats.

  American journal of physiology. Heart and circulatory physiology 20110701

• Down-regulation of DDAH2 and eNOS induces endothelial dysfunction in sinoaortic-denervated rats.

  European journal of pharmacology 20110701

• Inhibition of renin-angiotensin system (RAS) reduces ventricular tachycardia risk by altering connexin43.

  Journal of molecular medicine (Berlin, Germany) 20110701

• Behavior of pharmaceuticals in waste water treatment plant in Japan.

  Bulletin of environmental contamination and toxicology 20110701

• Evidence of an intracellular angiotensin-generating system and non-AT1, non-AT2 binding site in a human pancreatic cell line.

  Pancreas 20110701

• Successful treatment of nephrotic syndrome caused by recurrent IgA nephropathy with chronic active antibody-mediated rejection three years after kidney transplantation.

  Clinical transplantation 20110701

• Effect of a reduction in uric acid on renal outcomes during losartan treatment: a post hoc analysis of the reduction of endpoints in non-insulin-dependent diabetes mellitus with the Angiotensin II Antagonist Losartan Trial.

  Hypertension (Dallas, Tex. : 1979) 20110701

• Effects of ticlopidine on pharmacokinetics of losartan and its main metabolite EXP-3174 in rats.

  Acta pharmacologica Sinica 20110701

• Caveolae are essential for angiotensin II type 1 receptor-mediated ANP secretion.

  Peptides 20110701

• Safety and tolerability of the direct renin inhibitor aliskiren in combination with angiotensin receptor blockers and thiazide diuretics: a pooled analysis of clinical experience of 12,942 patients.

  Journal of clinical hypertension (Greenwich, Conn.) 20110701

• Tube feeding and drugs in intensive care unit.

  Anaesthesia and intensive care 20110701

• 2-(4-Methyl-phen-yl)benzonitrile.

  Acta crystallographica. Section E, Structure reports online 20110701

• Irbesartan attenuates ischemic brain damage by inhibition of MCP-1/CCR2 signaling pathway beyond AT₁ receptor blockade.

  Biochemical and biophysical research communications 20110603

• Economic evaluation of irbesartan in combination with hydrochlorothiazide in the treatment of hypertension in Greece.

  The European journal of health economics : HEPAC : health economics in prevention and care 20110601

• Olmesartan/amlodipine vs olmesartan/hydrochlorothiazide in hypertensive patients with metabolic syndrome: the OLAS study.

  Journal of human hypertension 20110601

• Differential effects of enalapril and losartan on body composition and indices of muscle quality in aged male Fischer 344 × Brown Norway rats.

  Age (Dordrecht, Netherlands) 20110601

• Antiarrhythmic effects of losartan and enalapril in canine pulmonary vein sleeve preparations.

  Journal of cardiovascular electrophysiology 20110601

• Combination treatment of angiotensin II type I receptor blocker and new oral iron chelator attenuates progression of nonalcoholic steatohepatitis in rats.

  American journal of physiology. Gastrointestinal and liver physiology 20110601

• Angiotensin-II type 1 receptor and NOX2 mediate TCF/LEF and CREB dependent WISP1 induction and cardiomyocyte hypertrophy.

  Journal of molecular and cellular cardiology 20110601

• Isolation and evaluation of a polysaccharide from Prunus amygdalus as a carrier for transbuccosal delivery of Losartan potassium.

  International journal of biological macromolecules 20110601

• Albuminuria and blood pressure, independent targets for cardioprotective therapy in patients with diabetes and nephropathy: a post hoc analysis of the combined RENAAL and IDNT trials.

  European heart journal 20110601

• Scintigraphic diagnosis of Erdheim-Chester disease.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110601

• Telmisartan exerts antiatherosclerotic effects by activating peroxisome proliferator-activated receptor-γ in macrophages.

  Arteriosclerosis, thrombosis, and vascular biology 20110601

• Combining blockers of the renin-angiotensin system or increasing the dose of an angiotensin II receptor antagonist in proteinuric patients: a randomized triple-crossover study.

  Journal of hypertension 20110601

• Effect of angiotensin II and its receptor antagonists on human corpus cavernous contractility and oxidative stress: modulation of nitric oxide mediated relaxation.

  The Journal of urology 20110601

• [Study of the efficacy and safety of losartan versus atenolol for aortic dilation in patients with Marfan syndrome].

  Revista espanola de cardiologia 20110601

• Autonomic imbalance: prophet of doom or scope for hope?

  Diabetic medicine : a journal of the British Diabetic Association 20110601

• Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus.

  Diabetes care 20110601

• Inhibiting TGF-β activity improves respiratory function in mdx mice.

  The American journal of pathology 20110601

• Managing erectile dysfunction in hypertensive patients.

  Journal of clinical hypertension (Greenwich, Conn.) 20110601

• The effect of an Angiotensin receptor blocker on arterial stiffness in type 2 diabetes mellitus patients with hypertension.

  Diabetes & metabolism journal 20110601

• Epigallocatechin-3-gallate Regulates Inducible Nitric Oxide Synthase Expression in Human Umbilical Vein Endothelial Cells.

  Laboratory animal research 20110601

• A sporadic case of Loeys-Dietz syndrome type I with two novel mutations of the TGFBR2 gene.

  Korean journal of pediatrics 20110601

• Comparative biophysical studies of sartan class drug molecules losartan and candesartan (CV-11974) with membrane bilayers.

  The journal of physical chemistry. B 20110519

• Losartan restores skeletal muscle remodeling and protects against disuse atrophy in sarcopenia.

  Science translational medicine 20110511

• Psoriasis induced by losartan therapy: a case report and review of the literature.

  American journal of therapeutics 20110501

• Mitigating effects of captopril and losartan on lung histopathology in a rat model of fat embolism.

  The Journal of trauma 20110501

• Novel therapeutic approaches for pulmonary fibrosis.

  British journal of pharmacology 20110501

• Tubular markers do not predict the decline in glomerular filtration rate in type 1 diabetic patients with overt nephropathy.

  Kidney international 20110501

• Low transition rate from normo- and low microalbuminuria to proteinuria in Japanese type 2 diabetic individuals: the Japan Diabetes Complications Study (JDCS).

  Diabetologia 20110501

• Efficacy and safety of mizoribine combined with losartan in the treatment of IgA nephropathy: a multicenter, randomized, controlled study.

  The American journal of the medical sciences 20110501

• Aliskiren vs. angiotensin receptor blockers in hypertension: meta-analysis of randomized controlled trials.

  American journal of hypertension 20110501

• Intrarenal transfer of an intracellular fluorescent fusion of angiotensin II selectively in proximal tubules increases blood pressure in rats and mice.

  American journal of physiology. Renal physiology 20110501

• CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay.

  Drug metabolism and disposition: the biological fate of chemicals 20110501

• Molecular mechanisms of angiotensin II stimulation on aquaporin-2 expression and trafficking.

  American journal of physiology. Renal physiology 20110501

• The effect of selective antihypertensive drugs on the vascular remodeling-associated hypertension: insights from a profilin1 transgenic mouse model.

  Journal of cardiovascular pharmacology 20110501

• Effect of angiotensin AT1 receptor blockade on sympathetic responses to handgrip in healthy men.

  American journal of hypertension 20110501

• Use of an adult rat retinal explant model for screening of potential retinal ganglion cell neuroprotective therapies.

  Investigative ophthalmology & visual science 20110501

• Aliskiren in combination with losartan reduces albuminuria independent of baseline blood pressure in patients with type 2 diabetes and nephropathy.

  Clinical journal of the American Society of Nephrology : CJASN 20110501

• Changes in subclinical organ damage vs. in Framingham risk score for assessing cardiovascular risk reduction during continued antihypertensive treatment: a LIFE substudy.

  Journal of hypertension 20110501

• Pharmacokinetic evaluation of losartan.

  Expert opinion on drug metabolism & toxicology 20110501

• Heterogeneity in antihypertensive treatment discontinuation between drugs belonging to the same class.

  Journal of hypertension 20110501

• Gadolinium increases the vascular reactivity of rat aortic rings.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20110501

• Role of angiotensin-1 receptor blockade in cirrhotic liver resection.

  Liver international : official journal of the International Association for the Study of the Liver 20110501

• Highly sensitive imaging of renal microcirculation in vivo using ultrahigh sensitive optical microangiography.

  Biomedical optics express 20110501

• An orally active formulation of angiotensin-(1-7) produces an antithrombotic effect.

  Clinics (Sao Paulo, Brazil) 20110501

• Impact of pulmonary vascular resistances in heart transplantation for congenital heart disease.

  Current cardiology reviews 20110501

• Candesartan vs losartan and mortality in patients with heart failure.

  JAMA 20110420

• Candesartan vs losartan and mortality in patients with heart failure.

  JAMA 20110420

• Medicine. Frightening risk of Marfan syndrome, and potential treatment, elucidated.

  Science (New York, N.Y.) 20110415

• Noncanonical TGFβ signaling contributes to aortic aneurysm progression in Marfan syndrome mice.

  Science (New York, N.Y.) 20110415

• Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism.

  Science (New York, N.Y.) 20110415

• Hydrogen sulfide attenuates cardiac dysfunction in a rat model of heart failure: a mechanism through cardiac mitochondrial protection.

  Bioscience reports 20110401

• Effects of commonly administered agents and genetics on nebivolol pharmacokinetics: drug-drug interaction studies.

  Journal of clinical pharmacology 20110401

• Telmisartan inhibits vasoconstriction via PPARγ-dependent expression and activation of endothelial nitric oxide synthase.

  Cardiovascular research 20110401

• Evaluation of metalloprotease inhibitors on hypertension and diabetic nephropathy.

  American journal of physiology. Renal physiology 20110401

• Serial assessment of the electrocardiographic strain pattern for prediction of new-onset heart failure during antihypertensive treatment: the LIFE study.

  European journal of heart failure 20110401

• Angiotensin-converting enzyme 2 deficiency in whole body or bone marrow-derived cells increases atherosclerosis in low-density lipoprotein receptor-/- mice.

  Arteriosclerosis, thrombosis, and vascular biology 20110401

• Endothelin-converting enzyme/neutral endopeptidase inhibitor SLV338 prevents hypertensive cardiac remodeling in a blood pressure-independent manner.

  Hypertension (Dallas, Tex. : 1979) 20110401

• Salt-induced renal injury in SHRs is mediated by AT1 receptor activation.

  Journal of hypertension 20110401

• Effects of telmisartan, irbesartan, valsartan, candesartan, and losartan on cancers in 15 trials enrolling 138,769 individuals.

  Journal of hypertension 20110401

• Adverse drug reaction profile of nanoparticle versus conventional formulation of paclitaxel: An observational study.

  Indian journal of pharmacology 20110401

• Effects of spironolactone and losartan on diabetic nephropathy in a type 2 diabetic rat model.

  Diabetes & metabolism journal 20110401

• [Effects of heart rate variability and smoothness index on the reversal of hypertensive left ventricular hypertrophy].

  Zhonghua yi xue za zhi 20110329

• Angiotensin receptor blockade improves the net balance of cardiac Ca(2+) handling-related proteins in sympathetic hyperactivity-induced heart failure.

  Life sciences 20110328

• Changes in electrocardiographic left ventricular hypertrophy and risk of major cardiovascular events in isolated systolic hypertension: the LIFE study.

  Journal of human hypertension 20110301

• Medial septal area ANG II receptor subtypes in the regulation of urine and sodium excretion induced by vasopressin.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20110301

• Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110301

• The frequency of factor V Leiden mutation, ACE gene polymorphism, serum ACE activity and response to ACE inhibitor and angiotensin II receptor antagonist drugs in Iranians type II diabetic patients with microalbuminuria.

  Molecular biology reports 20110301

• Endothelium-dependent vasomotor effects of telmisartan in isolated rat femoral arteries.

  Pharmacological research 20110301

• The effect of losartan treatment on the response of diabetic cardiomyocytes to ATP depletion.

  Pharmacological research 20110301

• Angiotensin II induces interleukin-6 synthesis in osteoblasts through ERK1/2 pathway via AT1 receptor.

  Archives of oral biology 20110301

• The effect of losartan and amlodipine on left ventricular diastolic function and atherosclerosis in Japanese patients with mild-to-moderate hypertension (J-ELAN) study.

  Hypertension research : official journal of the Japanese Society of Hypertension 20110301

• Tachycardia of atrial myocytes induces collagen expression in atrial fibroblasts through transforming growth factor β1.

  Cardiovascular research 20110301

• Obesity and gastrointestinal hormones-dual effect of angiotensin II receptor blockade and a partial agonist of PPAR-γ.

  Current vascular pharmacology 20110301

• Are we ready to use aliskiren in children?

  Pediatric nephrology (Berlin, Germany) 20110301

• ANG II type I receptor antagonism improved nitric oxide production and enhanced eNOS and PKB/Akt expression in hearts from a rat model of insulin resistance.

  Molecular and cellular biochemistry 20110301

• Angiotensin II differentially modulates cyclooxygenase-2, microsomal prostaglandin E2 synthase-1 and prostaglandin I2 synthase expression in adventitial fibroblasts exposed to inflammatory stimuli.

  Journal of hypertension 20110301

• Gene expression, function and ischemia tolerance in male and female rat hearts after sub-toxic levels of angiotensin II.

  Cardiovascular toxicology 20110301

• Glucocorticoid-induced fetal programming alters the functional complement of angiotensin receptor subtypes within the kidney.

  Hypertension (Dallas, Tex. : 1979) 20110301

• Sympathetic response to insulin is mediated by melanocortin 3/4 receptors in the hypothalamic paraventricular nucleus.

  Hypertension (Dallas, Tex. : 1979) 20110301

• Angiotensinergic signaling in the brain mediates metabolic effects of deoxycorticosterone (DOCA)-salt in C57 mice.

  Hypertension (Dallas, Tex. : 1979) 20110301

• Impaired interaction between efferent and afferent renal nerve activity in SHR involves increased activation of alpha2-adrenoceptors.

  Hypertension (Dallas, Tex. : 1979) 20110301

• Comparative clinical- and cost-effectiveness of candesartan and losartan in the management of hypertension and heart failure: a systematic review, meta- and cost-utility analysis.

  International journal of clinical practice 20110301

• Easy money? Health cost savings resulting from the switch from a branded drug to a low-cost generic drug in the same class.

  International journal of clinical practice 20110301

• Waste not, want not: free money, moral hazard and value-based prescribing.

  International journal of clinical practice 20110301

• Dietary salt intake and mortality in patients with type 2 diabetes.

  Diabetes care 20110301

• Losartan decreases cardiac muscle fibrosis and improves cardiac function in dystrophin-deficient mdx mice.

  Journal of cardiovascular pharmacology and therapeutics 20110301

• Racial differences in incident heart failure during antihypertensive therapy.

  Circulation. Cardiovascular quality and outcomes 20110301

• Cardiovascular events in subgroups of patients during primary treatment of hypertension with candesartan or losartan.

  Journal of clinical hypertension (Greenwich, Conn.) 20110301

• Prevention of systemic and regional haemodynamic alterations, hypercreatininemia, hyperuremia and hyperphosphatemia by losartan in hypertension with acute renal failure.

  Acta physiologica Hungarica 20110301

• MTHFR C677T polymorphism as a risk factor for vascular calcification in chronic hemodialysis patients.

  Journal of Korean medical science 20110301

• Arterial tortuosity syndrome with multiple intracranial aneurysms: a case report.

  Archives of neurology 20110301

• Heart failure prevention is the best option to stem high costs and disease burden: research for more effective heart failure treatment is needed.

  Circulation. Cardiovascular quality and outcomes 20110301

• Spurious hyperkalaemia: an insight.

  JPMA. The Journal of the Pakistan Medical Association 20110301

• Depressogenic effects of medications: a review.

  Dialogues in clinical neuroscience 20110301

• [Experimental study of (Pro)renin receptor siRNA inhibiting retinal neovascularization].

  [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20110301

• Evaluation of the effects of losartan on a random pattern skin flap model in rats.

  Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES 20110301

• An Insufficient Preoperative Diagnosis of Borrmann Type 4 Gastric Cancer in Spite of EMR.

  Journal of gastric cancer 20110301

• The angiotensin II type 1 receptor antagonist Losartan binds and activates bradykinin B2 receptor signaling.

  Regulatory peptides 20110225

• Angiotensin1-9 antagonises pro-hypertrophic signalling in cardiomyocytes via the angiotensin type 2 receptor.

  The Journal of physiology 20110215

• Supramolecular interactions between losartan and hydroxypropyl-β-CD: ESI mass-spectrometry, NMR techniques, phase solubility, isothermal titration calorimetry and anti-hypertensive studies.

  International journal of pharmaceutics 20110214

• Health-care costs of losartan and candesartan in the primary treatment of hypertension.

  Journal of human hypertension 20110201

• The effects of poststroke captopril and losartan treatment on cerebral blood flow autoregulation in SHRsp with hemorrhagic stroke.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110201

• High glucose upregulates upstream stimulatory factor 2 in human renal proximal tubular cells through angiotensin II-dependent activation of CREB.

  Nephron. Experimental nephrology 20110201

• Angiotensin II diminishes the effect of SGK1 on the WNK4-mediated inhibition of ROMK1 channels.

  Kidney international 20110201

• Rho kinase inhibition protects kidneys from diabetic nephropathy without reducing blood pressure.

  Kidney international 20110201

• FGF-23 as a predictor of renal outcome in diabetic nephropathy.

  Clinical journal of the American Society of Nephrology : CJASN 20110201

• Effect of renal sympathetic nerve on adrenergically and angiotensin II-induced renal vasoconstriction in normal Wistar-Kyoto rats.

  Upsala journal of medical sciences 20110201

• Pressor effect of apelin-13 in the rostral ventrolateral medulla: role of NAD(P)H oxidase-derived superoxide.

  The Journal of pharmacology and experimental therapeutics 20110201

• Role of plasma aldosterone concentration in regression of left-ventricular mass following antihypertensive medication.

  Journal of hypertension 20110201

• Endogenous angiotensin II suppresses stretch-induced ANP secretion via AT1 receptor pathway.

  Peptides 20110201

• Calcium channel blocker and Rho-associated kinase activity in patients with hypertension.

  Journal of hypertension 20110201

• Changes in angiotensin receptors expression play a pivotal role in the renal damage observed in spontaneously hypertensive rats.

  American journal of physiology. Renal physiology 20110201

• Enhanced angiotensin II-mediated central sympathoexcitation in streptozotocin-induced diabetes: role of superoxide anion.

  American journal of physiology. Regulatory, integrative and comparative physiology 20110201

• Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report.

  Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20110201

• Angiotensin AT1 receptors in paraventricular nucleus contribute to sympathetic activation and enhanced cardiac sympathetic afferent reflex in renovascular hypertensive rats.

  Experimental physiology 20110201

• Dietary sodium modulates the interaction between efferent and afferent renal nerve activity by altering activation of α2-adrenoceptors on renal sensory nerves.

  American journal of physiology. Regulatory, integrative and comparative physiology 20110201

• AT1 receptors in the paraventricular nucleus mediate the hyperthermia-induced reflex reduction of renal blood flow in rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20110201

• Additive effect of PPAR-γ agonist and ARB in treatment of experimental IgA nephropathy.

  Pediatric nephrology (Berlin, Germany) 20110201

• Blockade of the renin-angiotensin system ameliorates apelin production in 3T3-L1 adipocytes.

  Cardiovascular drugs and therapy 20110201

• High rate of regression from micro-macroalbuminuria to normoalbuminuria in children and adolescents with type 1 diabetes treated or not with enalapril: the influence of HDL cholesterol.

  Diabetes care 20110201

• Does renin-angiotensin system blockade have a role in preventing diabetic retinopathy? A clinical review.

  International journal of clinical practice 20110201

• Effect of celecoxib on the antihypertensive effect of losartan in a rat model of renovascular hypertension.

  Canadian journal of physiology and pharmacology 20110201

• Clinical trials of antihypertensives: Nature of control and design.

  Indian journal of pharmacology 20110201

• World Kidney Day 2011 - Protect your kidneys, save your heart.

  Archives of medical science : AMS 20110201

• Atrial fibrillation induces myocardial fibrosis through angiotensin II type 1 receptor-specific Arkadia-mediated downregulation of Smad7.

  Circulation research 20110121

• Blockade of 5-HT3 receptors at septal area increase blood pressure in unanaesthetized rats.

  Autonomic neuroscience : basic & clinical 20110120

• Adrenal beta-arrestin 1 inhibition in vivo attenuates post-myocardial infarction progression to heart failure and adverse remodeling via reduction of circulating aldosterone levels.

  Journal of the American College of Cardiology 20110118

• Co-operative effects of angiotensin II and caerulein in NFκB activation in pancreatic acinar cells in vitro.

  Regulatory peptides 20110117

• Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea.

  Brain research 20110112

• Association of candesartan vs losartan with all-cause mortality in patients with heart failure.

  JAMA 20110112

• Gout therapeutics: new drugs for an old disease.

  Lancet (London, England) 20110108

• Medical therapy for advanced pancreatic cancer: work in progress.

  JOP : Journal of the pancreas 20110105

• The Ayurvedic Medicine Salacia oblonga Attenuates Diabetic Renal Fibrosis in Rats: Suppression of Angiotensin II/AT1 Signaling.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Losartan vs. amlodipine treatment in elderly oncologic hypertensive patients: a randomized clinical trial.

  Archives of gerontology and geriatrics 20110101

• Sympathetic neurons express and secrete MMP-2 and MT1-MMP to control nerve sprouting via pro-NGF conversion.

  Cellular and molecular neurobiology 20110101

• Preferential accumulation and export of high molecular weight FGF-2 by rat cardiac non-myocytes.

  Cardiovascular research 20110101

• Naloxone, but not valsartan, preserves responses to hypoglycemia after antecedent hypoglycemia: role of metabolic reprogramming in counterregulatory failure.

  Diabetes 20110101

• Blockade of the Renin-Angiotensin system improves insulin receptor signaling and insulin-stimulated skeletal muscle glucose transport in burn injury.

  Shock (Augusta, Ga.) 20110101

• ACE gene polymorphism and serum ACE activity in Iranians type II diabetic patients with macroalbuminuria.

  Molecular and cellular biochemistry 20110101

• Effects of systemic inhibition of Rho kinase on blood pressure and renal haemodynamics in diabetic rats.

  British journal of pharmacology 20110101

• The acute effect of clamped hyperglycemia on the urinary excretion of inflammatory cytokines/chemokines in uncomplicated type 1 diabetes: a pilot study.

  Diabetes care 20110101

• Increased serum potassium affects renal outcomes: a post hoc analysis of the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial.

  Diabetologia 20110101

• Pravastatin normalises peripheral cardiac sympathetic hyperactivity in the spontaneously hypertensive rat.

  Journal of molecular and cellular cardiology 20110101

• Sirolimus damages podocytes in rats with protein overload nephropathy.

  Journal of nephrology 20110101

• Involvement of the AT1 receptor in the venoconstriction induced by angiotensin II in both the inferior vena cava and femoral vein.

  Peptides 20110101

• Endothelin-1 and angiotensin II modulate rate and contraction amplitude in a subpopulation of mouse embryonic stem cell-derived cardiomyocyte-containing bodies.

  Stem cell research 20110101

• Mechanisms related to NO-induced motility in differentiated rat aortic smooth muscle cells.

  American journal of physiology. Heart and circulatory physiology 20110101

• Angiotensin II induces afterdepolarizations via reactive oxygen species and calmodulin kinase II signaling.

  Journal of molecular and cellular cardiology 20110101

• Regulation of posttranscriptional modification as a possible therapeutic approach for retinal neuroprotection.

  Journal of ophthalmology 20110101

• Different actions of losartan and ramipril on adipose tissue activity and vascular remodeling biomarkers in hypertensive patients.

  Hypertension research : official journal of the Japanese Society of Hypertension 20110101

• Comparison of the effects of losartan vs. ramipril on several adipocytokines and vascular remodeling biomarkers.

  Hypertension research : official journal of the Japanese Society of Hypertension 20110101

• Lack of heterologous receptor desensitization induced by angiotensin II type 1 receptor activation in isolated normal rat thoracic aorta.

  Vascular pharmacology 20110101

• Compliance, persistence, healthcare resource use, and treatment costs associated with aliskiren plus ARB versus ACE inhibitor plus ARB combination therapy: in US patients with hypertension.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20110101

• Effects of losartan/hydrochlorothiazide treatment, after change from ARB at usual dosage, on blood pressure and various metabolic parameters including high-molecular weight adiponectin in Japanese male hypertensive subjects.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20110101

• The cardiorenal syndrome: making the connection.

  International journal of nephrology 20110101

• The effect of losartan and carvedilol on vasopressor responses to adrenergic agonists and angiotensin II in the systemic circulation of Sprague Dawley rats.

  Autonomic & autacoid pharmacology 20110101

• Captopril and losartan for mitigation of renal injury caused by single-dose total-body irradiation.

  Radiation research 20110101

• Clinical drugs undergoing polymorphic metabolism by human cytochrome P450 2C9 and the implication in drug development.

  Current medicinal chemistry 20110101

• Extracellular matrix of collagen modulates intracellular calcium handling and electrophysiological characteristics of HL-1 cardiomyocytes with activation of angiotensin II type 1 receptor.

  Journal of cardiac failure 20110101

• Standards of medical care in diabetes--2011.

  Diabetes care 20110101

• Clinical pearls in general internal medicine.

  Mayo Clinic proceedings 20110101

• Diabetes: Treatment with losartan increases risk of adverse renal outcomes.

  Nature reviews. Endocrinology 20110101

• Local bone marrow Renin-Angiotensin system and atherosclerosis.

  Cardiology research and practice 20110101

• Resistant hypertension workup and approach to treatment.

  International journal of hypertension 20110101

• Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin.

  Trials 20110101

• Synergistic effect of combined HMG-CoA reductase inhibitor and angiotensin-II receptor blocker therapy in patients with chronic heart failure: the HF-COSTAR trial.

  Circulation journal : official journal of the Japanese Circulation Society 20110101

• Novel adiponectin-resistin (AR) and insulin resistance (IRAR) indexes are useful integrated diagnostic biomarkers for insulin resistance, type 2 diabetes and metabolic syndrome: a case control study.

  Cardiovascular diabetology 20110101

• Costarring statins with ARBs: going to be a smash hit?

  Circulation journal : official journal of the Japanese Circulation Society 20110101

• Aortocaval fistula in rat: a unique model of volume-overload congestive heart failure and cardiac hypertrophy.

  Journal of biomedicine & biotechnology 20110101

• A randomized, double-blind, forced-titration study to compare olmesartan medoxomil versus losartan potassium in patients with stage 1 and 2 hypertension.

  Postgraduate medicine 20110101

• Central angiotensin II stimulation promotes β amyloid production in Sprague Dawley rats.

  PloS one 20110101

• Anti-inflammatory effects of anti-hypertensive agents: influence on interleukin-1β secretion by peripheral blood polymorphonuclear leukocytes from patients with essential hypertension.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20110101

• Novel therapies for resistant focal segmental glomerulosclerosis (FONT) phase II clinical trial: study design.

  BMC nephrology 20110101

• Effects of fosinopril and losartan on renal Klotho expression and oxidative stress in spontaneously hypertensive rats.

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20110101

• [Effect of AT₁ receptor on changes of tyrosine hydroxylase-immunoreactivity in rostral ventrolateral medulla induced by brain cholinergic stimuli in rats].

  Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110101

• Angiotensin II induces the expression of c-reactive protein via MAPK-dependent signal pathway in U937 macrophages.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101

• High dose astaxanthin lowers blood pressure and increases insulin sensitivity in rats: are these effects interdependent?

  International journal of medical sciences 20110101

• Sympathetic renal innervation and resistant hypertension.

  International journal of hypertension 20110101

• Ask the doctor. I heard about a study that found that ARBs can cause cancer. I am taking one, Cozaar, because of high blood pressure. Should I stop taking it?

  Harvard health letter 20110101

• A comparison between diuretics and angiotensin-receptor blocker agents in patients with stage I hypertension (PREVER-treatment trial): study protocol for a randomized double-blind controlled trial.

  Trials 20110101

• Impairment of the Plasmodium falciparum erythrocytic cycle induced by angiotensin peptides.

  PloS one 20110101

• Low-level lead exposure increases systolic arterial pressure and endothelium-derived vasodilator factors in rat aortas.

  PloS one 20110101

• [Progress of pediatric nephrology].

  Nihon Jinzo Gakkai shi 20110101

• Telmisartan in incipient and overt diabetic renal disease.

  Journal of nephrology 20110101

• Olmesartan, an AT1 antagonist, attenuates oxidative stress, endoplasmic reticulum stress and cardiac inflammatory mediators in rats with heart failure induced by experimental autoimmune myocarditis.

  International journal of biological sciences 20110101

• Use of Angiotensin receptor blockers in cardiovascular protection: current evidence and future directions.

  P & T : a peer-reviewed journal for formulary management 20110101

• Prevalence and distribution of regional scar in dysfunctional myocardial segments in Duchenne muscular dystrophy.

  Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101

• Animal models of cardiovascular diseases.

  Journal of biomedicine & biotechnology 20110101

• Sex differences in drug disposition.

  Journal of biomedicine & biotechnology 20110101

• Renal protection with angiotensin receptor blockers: where do we stand.

  Journal of nephrology 20110101

• Changes in the organization of excitation-contraction coupling structures in failing human heart.

  PloS one 20110101

• Candesartan cilexetil/hydrochlorothiazide combination treatment versus high-dose candesartan cilexetil monotherapy in patients with mild to moderate cardiovascular risk (CHILI Triple T).

  Vascular health and risk management 20110101

• Common secondary causes of resistant hypertension and rational for treatment.

  International journal of hypertension 20110101

• A causative link between periodontal disease and glomerulonephritis: a preliminary study.

  Therapeutics and clinical risk management 20110101

• The Ras antagonist, farnesylthiosalicylic acid (FTS), decreases fibrosis and improves muscle strength in dy/dy mouse model of muscular dystrophy.

  PloS one 20110101

• Role of the kidneys in resistant hypertension.

  International journal of hypertension 20110101

• Pharmaco-economic consequences of losartan therapy in patients undergoing diabetic end stage renal disease in EU and USA.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20110101

• Treatment options for hypertension in high-risk patients.

  Vascular health and risk management 20110101

• Change of telomere length in angiotensin II-induced human glomerular mesangial cell senescence and the protective role of losartan.

  Molecular medicine reports 20110101

• Angiotensin II receptor blocker, losartan, ameliorates gentamicin-induced oxidative stress and nephrotoxicity in rats.

  Pharmacology 20110101

• Differences in abundances of cell-signalling proteins in blood reveal novel biomarkers for early detection of clinical Alzheimer's disease.

  PloS one 20110101

• Inhibition of renin-angiotensin system reverses endothelial dysfunction and oxidative stress in estrogen deficient rats.

  PloS one 20110101

• Olmesartan medoxomil for the treatment of hypertension in children and adolescents.

  Vascular health and risk management 20110101

• Olmesartan/amlodipine: a review of its use in the management of hypertension.

  Vascular health and risk management 20110101

• Screening for left ventricular hypertrophy in patients with type 2 diabetes mellitus in the community.

  Cardiovascular diabetology 20110101

• Tanshinone IIA protects against cardiac hypertrophy via inhibiting calcineurin/NFATc3 pathway.

  International journal of biological sciences 20110101

• Acute lead exposure increases arterial pressure: role of the renin-angiotensin system.

  PloS one 20110101

• [Remarkable results with candesartan].

  Nederlands tijdschrift voor geneeskunde 20110101

• BICEPP: an example-based statistical text mining method for predicting the binary characteristics of drugs.

  BMC bioinformatics 20110101

• [Effect of losartan, lisinopril and their combination on hemodynamics and morphofunctional parameters of the heart in patients with chronic cardiac failure].

  Klinicheskaia meditsina 20110101

• Angiotensin receptor blockers and risk of myocardial infarction: meta-analyses and trial sequential analyses of 147 020 patients from randomised trials.

  BMJ (Clinical research ed.) 20110101

• Time course of collagen peak in bile duct-ligated rats.

  BMC gastroenterology 20110101

• Losartan and pioglitazone ameliorate nephropathy in experimental metabolic syndrome rats.

  Biological & pharmaceutical bulletin 20110101

• The rostral migratory stream plays a key role in intranasal delivery of drugs into the CNS.

  PloS one 20110101

• The prognostic value of non-linear analysis of heart rate variability in patients with congestive heart failure--a pilot study of multiscale entropy.

  PloS one 20110101

• Strain differences and the role of AT(1) receptor expression in anxiety.

  International journal of molecular epidemiology and genetics 20110101

• Nephrotic syndrome and idiopathic membranous nephropathy associated with autosomal-dominant polycystic kidney disease.

  TheScientificWorldJournal 20110101

• Major inducing factors of hypertensive complications and the interventions required to reduce their prevalence: an epidemiological study of hypertension in a rural population in China.

  BMC public health 20110101

• Incidence of atrial fibrillation in patients with either heart failure or acute myocardial infarction and left ventricular dysfunction: a cohort study.

  BMC cardiovascular disorders 20110101

• Clinical utility of valsartan in the treatment of hypertension in children and adolescents.

  Patient preference and adherence 20110101

• [Assessment of the results of 24-hour arterial pressure monitoring in patients with arterial hypertension treated with fixed combinations of co-renitec and gyzaar with and without acupuncture reflexotherapy].

  Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury 20110101

• Phase I Clinical Study of the Dietary Supplement, Agaricus blazei Murill, in Cancer Patients in Remission.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Involvement of profilin-1 in angiotensin II-induced vascular smooth muscle cell proliferation.

  Vascular pharmacology 20110101

• Cardiovascular and Renal Links along the Cardiorenal Continuum.

  International journal of nephrology 20110101

• ARB treatment prevents the decrease in endothelial progenitor cells and the loss of renal microvasculature in remnant kidney.

  American journal of nephrology 20110101

• Rapid simultaneous determination of telmisartan, amlodipine besylate and hydrochlorothiazide in a combined poly pill dosage form by stability-indicating ultra performance liquid chromatography.

  Scientia pharmaceutica 20110101

• Left ventricular geometric patterns and adaptations to hemodynamics are similar in elderly men and women.

  BMC cardiovascular disorders 20110101

• Combination delapril/manidipine as antihypertensive therapy in high-risk patients.

  Clinical drug investigation 20110101

• Quantifying differential gene connectivity between disease states for objective identification of disease-relevant genes.

  BMC systems biology 20110101

• Novel ocular antihypertensive compounds in clinical trials.

  Clinical ophthalmology (Auckland, N.Z.) 20110101

• Prolonged Refractory Hypotension following Combined Amlodipine and Losartan Ingestion Responsive to Metaraminol.

  Case reports in medicine 20110101

• Long-term use of aldosterone-receptor antagonists in uncontrolled hypertension: a retrospective analysis.

  International journal of hypertension 20110101

• Reappraisal of role of angiotensin receptor blockers in cardiovascular protection.

  Vascular health and risk management 20110101

• A current evaluation of the safety of angiotensin receptor blockers and direct renin inhibitors.

  Vascular health and risk management 20110101

• Fosinopril and losartan regulate klotho gene and nicotinamide adenine dinucleotide phosphate oxidase expression in kidneys of spontaneously hypertensive rats.

  Kidney & blood pressure research 20110101

• Vitamin d receptor activators and clinical outcomes in chronic kidney disease.

  International journal of nephrology 20110101

• Switching therapy from variable-dose multiple pill to fixed-dose single-pill combinations of angiotensin II receptor blockers and thiazides for hypertension.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20110101

• Association of angiotensin-converting enzyme gene I/D polymorphism with steroid responsiveness in childhood nephrotic syndrome.

  Indian journal of nephrology 20110101

• Collagenofibrotic glomerulopathy - Case report with review of literature.

  Indian journal of nephrology 20110101

• Hypoxemia in patients with COPD: cause, effects, and disease progression.

  International journal of chronic obstructive pulmonary disease 20110101

• PLCβ1-SHP-2 complex, PLCβ1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling?

  Journal of biomedical science 20110101

• Aliskiren: An orally active renin inhibitor.

  Journal of pharmacy & bioallied sciences 20110101

• Stroke, high blood pressure and the Renin-Angiotensin-aldosterone system - new developments.

  Frontiers in pharmacology 20110101

• Diabetic microvascular complications: possible targets for improved macrovascular outcomes.

  International journal of nephrology and renovascular disease 20110101

• Role of aliskiren in blood pressure control and renoprotection.

  International journal of nephrology and renovascular disease 20110101

• GENT: gene expression database of normal and tumor tissues.

  Cancer informatics 20110101

• Decorin and colchicine as potential treatments for post-haemorrhagic ventricular dilatation in a neonatal rat model.

  Neonatology 20110101

• Choice of angiotensin receptor blocker in moderate hypertension. A UK-based cost-benefit comparison of olmesartan- and candesartan-based regimens.

  Journal of medical economics 20110101

• Effects of HMG-CoA reductase inhibitors on the pharmacokinetics of losartan and its main metabolite EXP-3174 in rats: possible role of CYP3A4 and P-gp inhibition by HMG-CoA reductase inhibitors.

  Pharmacology 20110101

• Cardiovascular risk factor treatment targets and renal complications in high risk vascular patients: a cohort study.

  BMC cardiovascular disorders 20110101

• Chronic losartan administration reduces mortality and preserves cardiac but not skeletal muscle function in dystrophic mice.

  PloS one 20110101

• The ECG vertigo in diabetes and cardiac autonomic neuropathy.

  Experimental diabetes research 20110101

• Metabolic programming during lactation stimulates renal Na+ transport in the adult offspring due to an early impact on local angiotensin II pathways.

  PloS one 20110101

• Hypertension in chronic kidney disease: navigating the evidence.

  International journal of hypertension 20110101

• Cardiac hypertrophy and fibrosis in the metabolic syndrome: a role for aldosterone and the mineralocorticoid receptor.

  International journal of hypertension 20110101

• Oxidative Stress and Vascular Damage in Hypertension: Role of Angiotensin II.

  International journal of hypertension 20110101

• The mechanosensory role of primary cilia in vascular hypertension.

  International journal of vascular medicine 20110101

• Donepezil, anti-Alzheimer's disease drug, prevents cardiac rupture during acute phase of myocardial infarction in mice.

  PloS one 20110101

• Oxidative stress in cardiovascular inflammation: its involvement in autoimmune responses.

  International journal of inflammation 20110101

• Differential Effects in Cardiovascular Markers between High-Dose Angiotensin II Receptor Blocker Monotherapy and Combination Therapy of ARB with Calcium Channel Blocker in Hypertension (DEAR Trial).

  International journal of hypertension 20110101

• Left ventricular hypertrophy: major risk factor in patients with hypertension: update and practical clinical applications.

  International journal of hypertension 20110101

• Vascular pathology in multiple sclerosis: mind boosting or myth busting?

  Experimental & translational stroke medicine 20110101

• Preventive effect of Ibrolipim on suppressing lipid accumulation and increasing lipoprotein lipase in the kidneys of diet-induced diabetic minipigs.

  Lipids in health and disease 20110101

• Diabetic nephropathy - Epidemiology in Asia and the current state of treatment.

  Indian journal of nephrology 20110101

• Late post-transplant erythrocytosis in a hepatitis C-positive allograft recipient on sirolimus.

  Indian journal of nephrology 20110101

• Dyslipidemia induced by drugs used for the prevention and treatment of vascular diseases.

  The open cardiovascular medicine journal 20110101

• Update on the Serum Biomarkers and Genetic Factors Associated with Safety and Efficacy of rt-PA Treatment in Acute Stroke Patients.

  Stroke research and treatment 20110101

• The Relation between Fructose-Induced Metabolic Syndrome and Altered Renal Haemodynamic and Excretory Function in the Rat.

  International journal of nephrology 20110101

• [The role of D2 vitamin metabolite paricalcitol in nephroprotective strategy in chronic disease of the kidneys].

  Terapevticheskii arkhiv 20110101

• Moderate dietary sodium restriction added to angiotensin converting enzyme inhibition compared with dual blockade in lowering proteinuria and blood pressure: randomised controlled trial.

  BMJ (Clinical research ed.) 20110101

• Evaluation of CYP450 inhibitory effects and steady-state pharmacokinetics of genistein in combination with cholecalciferol and citrated zinc bisglycinate in postmenopausal women.

  International journal of women's health 20110101

• The roles of buyang huanwu decoction in anti-inflammation, antioxidation and regulation of lipid metabolism in rats with myocardial ischemia.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Inflammatory regulation of valvular remodeling: the good(?), the bad, and the ugly.

  International journal of inflammation 20110101

• Cardiovascular outcomes with angiotensin II receptor blockers: clinical implications of recent trials.

  Vascular health and risk management 20110101

• Optimal therapeutic strategy for treating patients with hypertension and atherosclerosis: focus on olmesartan medoxomil.

  Vascular health and risk management 20110101

• The effects of chronic losartan pretreatment on restraint stress-induced changes in motor activity, nociception and pentylenetetrazol generalized seizures in rats.

  Folia medica 20110101

• Combination of angiotensin II receptor antagonist with calcium channel blocker or diuretic as antihypertensive therapy for patients with chronic kidney disease.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20110101

• δ-Sarcoglycan-deficient muscular dystrophy: from discovery to therapeutic approaches.

  Skeletal muscle 20110101

• Role of TGF-β signaling in inherited and acquired myopathies.

  Skeletal muscle 20110101

• Aberrant repair and fibrosis development in skeletal muscle.

  Skeletal muscle 20110101

• Caloric intake, dietary lifestyles, macronutrient composition, and alzheimer' disease dementia.

  International journal of Alzheimer's disease 20110101

• Clopidogrel effectively suppresses endothelial microparticle generation induced by indoxyl sulfate via inhibition of the p38 mitogen-activated protein kinase pathway.

  Blood purification 20110101

• Angiotensin II Type 1 Receptors and Systemic Hemodynamic and Renal Responses to Stress and Altered Blood Volume in Conscious Rabbits.

  Frontiers in physiology 20110101

• ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function.

  PloS one 20110101

• Comparative effect of olmesartan and candesartan on lipid metabolism and renal function in patients with hypertension: a retrospective observational study.

  Cardiovascular diabetology 20110101

• Reciprocal roles of angiotensin II and Angiotensin II Receptors Blockade (ARB) in regulating Cbfa1/RANKL via cAMP signaling pathway: possible mechanism for hypertension-related osteoporosis and antagonistic effect of ARB on hypertension-related osteoporosis.

  International journal of molecular sciences 20110101

• Impaired vascular contractility and aortic wall degeneration in fibulin-4 deficient mice: effect of angiotensin II type 1 (AT1) receptor blockade.

  PloS one 20110101

• Urinary angiotensinogen as a biomarker of nephropathy in childhood.

  International journal of nephrology 20110101

• The 'smoker's paradox' in patients with acute coronary syndrome: a systematic review.

  BMC medicine 20110101

• Drug Delivery: Enabling Technology for Drug Discovery and Development. iPRECIO Micro Infusion Pump: Programmable, Refillable, and Implantable.

  Frontiers in pharmacology 20110101

• Where are we heading with noninvasive clinical vascular physiology? Why and how should we assess endothelial function?

  Cardiology research and practice 20110101

• Spectrum of antihypertensive therapy in South Asians at a tertiary care hospital in Pakistan.

  BMC research notes 20110101

• Validated RP-HPLC Method for Simultaneous Quantitation of Losartan Potassium and Metolazone in Bulk Drug and Formulation.

  Scientia pharmaceutica 20110101

• Amoxicillin loaded chitosan-alginate polyelectrolyte complex nanoparticles as mucopenetrating delivery system for h. Pylori.

  Scientia pharmaceutica 20110101

• The relationship of ethnicity to the prevalence and management of hypertension and associated chronic kidney disease.

  BMC nephrology 20110101

• Prevention and intervention studies with telmisartan, ramipril and their combination in different rat stroke models.

  PloS one 20110101

• Rituximab resistant evans syndrome and autoimmunity in Schimke immuno-osseous dysplasia.

  Pediatric rheumatology online journal 20110101

• Thrombotic thrombocytopenic purpura associated with mixed connective tissue disease: a case report.

  Case reports in medicine 20110101

• Vascular inflammation and endothelial dysfunction in experimental hypertension.

  International journal of hypertension 20110101

• Jak2-Independent Activation of Stat3 by Intracellular Angiotensin II in Human Mesangial Cells.

  Journal of signal transduction 20110101

• Simultaneous determination of amlodipine and valsartan.

  Analytical chemistry insights 20110101

• A critical appraisal of the clinical effectiveness of a fixed combination of valsartan, amlodipine, and hydrochlorothiazide in achieving blood pressure goals.

  Integrated blood pressure control 20110101

• Long-term use and tolerability of irbesartan for control of hypertension.

  Integrated blood pressure control 20110101

• Short- and long-term physiologic and pharmacologic control of blood pressure in pediatric patients.

  Integrated blood pressure control 20110101

• Expression and function of osteopontin in vascular adventitial fibroblasts and pathological vascular remodeling.

  PloS one 20110101

• Beneficial effect of switching from a combination of angiotensin II receptor blockers other than losartan and thiazides to a fixed dose of losartan/hydrochlorothiazide on uric acid metabolism in hypertensive patients.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20110101

• Clinical characterization of symptomatic microangiopathic brain lesions.

  Frontiers in neurology 20110101

• Gαq-protein carboxyl terminus imitation polypeptide GCIP-27 attenuates proliferation of vascular smooth muscle cells and vascular remodeling in spontaneously hypertensive rats.

  Biological & pharmaceutical bulletin 20110101

• Oxidative damages in tubular epithelial cells in IgA nephropathy: role of crosstalk between angiotensin II and aldosterone.

  Journal of translational medicine 20110101

• Generation of reactive oxygen species in 1-methyl-4-phenylpyridinium (MPP+) treated dopaminergic neurons occurs as an NADPH oxidase-dependent two-wave cascade.

  Journal of neuroinflammation 20110101

• RhoA distribution in renal caveolar fractions in experimental type 1 diabetes.

  Folia biologica 20110101

• Novel microwell-based spectrophotometric assay for determination of atorvastatin calcium in its pharmaceutical formulations.

  Chemistry Central journal 20110101

• Inhibition of cardiac sympathetic afferent reflex and sympathetic activity by baroreceptor and vagal afferent inputs in chronic heart failure.

  PloS one 20110101

• Functional evaluation of genetic and environmental regulators of p450 mRNA levels.

  PloS one 20110101

• The effect of short-term canola oil ingestion on oxidative stress in the vasculature of stroke-prone spontaneously hypertensive rats.

  Lipids in health and disease 20110101

• Spice up the hypertension diet - curcumin and piperine prevent remodeling of aorta in experimental L-NAME induced hypertension.

  Nutrition & metabolism 20110101

• Eplerenone prevents salt-induced vascular stiffness in Zucker diabetic fatty rats: a preliminary report.

  Cardiovascular diabetology 20110101

• Effects of steroids and angiotensin converting enzyme inhibition on circumferential strain in boys with Duchenne muscular dystrophy: a cross-sectional and longitudinal study utilizing cardiovascular magnetic resonance.

  Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101

• Ranitidine anaphylaxis: A rare occurrence.

  Indian journal of anaesthesia 20110101

• Molecular mechanisms of left ventricular hypertrophy (LVH) in systemic hypertension (SH)-possible therapeutic perspectives.

  Journal of the American Society of Hypertension : JASH 20110101

• Multimodal cardiovascular magnetic resonance quantifies regional variation in vascular structure and function in patients with coronary artery disease: relationships with coronary disease severity.

  Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101

• Inverse agonism and its therapeutic significance.

  Indian journal of pharmacology 20110101

• Night-time exogenous melatonin administration may be a beneficial treatment for sleeping disorders in beta blocker patients.

  Journal of cardiovascular disease research 20110101

• Efficacy of fixed-dose amlodipine and losartan combination compared with amlodipine monotherapy in stage 2 hypertension: a randomized, double blind, multicenter study.

  BMC research notes 20110101

• Comparison of the efficacy and safety of single-pill fixed-dose combinations of losartan/hydrochlorothiazide and valsartan/hydrochlorothiazide in patients with hypertension (SALT-VAT study).

  Internal medicine (Tokyo, Japan) 20110101

• Predicting in vivo anti-hepatofibrotic drug efficacy based on in vitro high-content analysis.

  PloS one 20110101

• Proteomic and transcriptomic analysis of heart failure due to volume overload in a rat aorto-caval fistula model provides support for new potential therapeutic targets - monoamine oxidase A and transglutaminase 2.

  Proteome science 20110101

• Role of blood cell-associated angiotensin II type 1 receptors in the cerebral microvascular response to ischemic stroke during angiotensin-induced hypertension.

  Experimental & translational stroke medicine 20110101

• Vascular involvement in systemic sclerosis (scleroderma).

  Journal of inflammation research 20110101

• Indications for and utilization of angiotensin receptor II blockers in patients at high cardiovascular risk.

  Vascular health and risk management 20110101

• The impact of dose of the angiotensin-receptor blocker valsartan on the post-myocardial infarction ventricular remodeling: study protocol for a randomized controlled trial.

  Trials 20110101

• Angiotensin II type II receptor deficiency accelerates the development of nephropathy in type I diabetes via oxidative stress and ACE2.

  Experimental diabetes research 20110101

• Design, synthesis, and pharmacological evaluation of haloperidol derivatives as novel potent calcium channel blockers with vasodilator activity.

  PloS one 20110101

• Identification and determination of selected angiotensin II receptor antagonist group drugs by HPLC method.

  Acta poloniae pharmaceutica 20110101

• Elevation of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline: a blood pressure-independent beneficial effect of angiotensin I-converting enzyme inhibitors.

  Fibrogenesis & tissue repair 20110101

• Gene-drug interaction in stroke.

  Stroke research and treatment 20110101

• Development of validated stability-indicating chromatographic method for the determination of fexofenadine hydrochloride and its related impurities in pharmaceutical tablets.

  Chemistry Central journal 20110101

• Telmisartan and cardioprotection.

  Vascular health and risk management 20110101

• Azathioprine induced cholestatic hepatitis.

  Indian journal of pharmacology 20110101

• Zofenopril and incidence of cough: a review of published and unpublished data.

  Therapeutics and clinical risk management 20110101

• The NTD Nanoscope: potential applications and implementations.

  BMC bioinformatics 20110101

• Ambulatory blood pressure response to triple therapy with an angiotensin-receptor blocker (ARB), calcium-channel blocker (CCB), and HCTZ versus dual therapy with an ARB and HCTZ.

  Vascular health and risk management 20110101

• [Lozartan potential in hyperuricemia correction].

  Terapevticheskii arkhiv 20110101

• Constructing a semantic predication gold standard from the biomedical literature.

  BMC bioinformatics 20110101

• Roles of TGF-β signals in endothelial-mesenchymal transition during cardiac fibrosis.

  International journal of inflammation 20110101

• Clinical and functional characterization of URAT1 variants.

  PloS one 20110101

• Antihypertensive treatment differentially affects vascular sphingolipid biology in spontaneously hypertensive rats.

  PloS one 20110101

• Cardiovascular agents affect the tone of pulmonary arteries and veins in precision-cut lung slices.

  PloS one 20110101

• Catastrophic complication - Bezold-Jarisch reflex: Case series.

  Indian journal of anaesthesia 20110101

• TRC120038, a Novel Dual AT(1)/ET(A) Receptor Blocker for Control of Hypertension, Diabetic Nephropathy, and Cardiomyopathy in ob-ZSF1 Rats.

  International journal of hypertension 20110101

• Critical review of cancer risk associated with angiotensin receptor blocker therapy.

  Vascular health and risk management 20110101

• Differential clinical profile of candesartan compared to other angiotensin receptor blockers.

  Vascular health and risk management 20110101

• Benefits of once-daily therapies in the treatment of hypertension.

  Vascular health and risk management 20110101

• Integrated control of hypertension by olmesartan medoxomil and hydrochlorothiazide and rationale for combination.

  Integrated blood pressure control 20110101

• Short-Term Calorie Restriction in Early Life Attenuates the Development of Proteinuria but Not Glucose Intolerance in Type 2 Diabetic OLETF Rats.

  ISRN endocrinology 20110101

• Novel Pharmacological Interventions to Maintain Sinus Rhythm after DC Cardioversion.

  ISRN cardiology 20110101

• Aggressive versus Low Dose Inhibition of the Renin-Angiotensin System for the Treatment of Microalbuminuria in Type 2 Diabetic Patients: A Pilot Study.

  ISRN endocrinology 20110101

• Results of a Pilot Randomized Placebo-Controlled Trial in Primary and Secondary Raynaud's Phenomenon with St. John's Wort: Detecting Changes in Angiogenic Cytokines When RP Improves.

  ISRN rheumatology 20110101

• Physical activity in the prevention and treatment of stroke.

  ISRN neurology 20110101

• A Sensitive RP-HPLC Method for Simultaneous Estimation of Diethylcarbamazine and Levocetirizine in Tablet Formulation.

  Indian journal of pharmaceutical sciences 20110101

• Quantitative estimation of urate transport in nephrons in relation to urinary excretion employing benzbromarone-loading urate clearance tests in cases of hyperuricemia.

  Nephron extra 20110101

• Attenuation of Immune-Mediated Renal Injury by Telmisartan, an Angiotensin Receptor Blocker and a Selective PPAR-γ Activator.

  Nephron extra 20110101

• [Current management of gout].

  Acta medica portuguesa 20110101

• The effect of contrast dye injection and balloon inflation on QTC and QTC dispersion in 12 leads surface EKG during PTCA.

  ARYA atherosclerosis 20110101

• Renoprotective effects of combining ACE inhibitors and statins in experimental diabetic rats.

  Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101

• Angiotensin II, a Neuropeptide at the Frontier between Endocrinology and Neuroscience: Is There a Link between the Angiotensin II Type 2 Receptor and Alzheimer's Disease?

  Frontiers in endocrinology 20110101

• A Stability-indicating High Performance Liquid Chromatographic Assay for the Simultaneous Determination of Atenolol and Lercanidipine Hydrochloride in Tablets.

  Indian journal of pharmaceutical sciences 20110101

• [Primary and secondary prevention of ischemic stroke].

  Le Journal medical libanais. The Lebanese medical journal 20110101

• Getting better value from the NHS drug budget.

  BMJ (Clinical research ed.) 20101217

• Differential effects of alendronate and losartan therapy on osteopenia and aortic aneurysm in mice with severe Marfan syndrome.

  Human molecular genetics 20101215

• Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.

  Bioorganic & medicinal chemistry 20101215

• The physicochemical properties, in vitro metabolism and pharmacokinetics of a novel ester prodrug of EXP3174.

  Molecular pharmaceutics 20101206

• Polymorphisms of human cytochrome P450 2C9 and the functional relevance.

  Toxicology 20101205

• Xenon/remifentanil anesthesia protects against adverse effects of losartan on hemodynamic challenges induced by anesthesia and acute blood loss.

  Shock (Augusta, Ga.) 20101201

• The effect of the expression of angiotensin II on extracellular matrix metalloproteinase inducer (EMMPRIN) in macrophages is mediated via the AT1/COX-2/PGE2 pathway.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20101201

• Early molecular imaging of interstitial changes in patients after myocardial infarction: comparison with delayed contrast-enhanced magnetic resonance imaging.

  Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20101201

• Acute hyperglycemia rapidly stimulates VEGF mRNA translation in the kidney. Role of angiotensin type 2 receptor (AT2).

  Cellular signalling 20101201

• Vascular structure and oxidative stress in salt-loaded spontaneously hypertensive rats: effects of losartan and atenolol.

  American journal of hypertension 20101201

• Regression of target organ damage in children and adolescents with primary hypertension.

  Pediatric nephrology (Berlin, Germany) 20101201

• Selectively engaging β-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance.

  The Journal of pharmacology and experimental therapeutics 20101201

• AT₁ receptor and NAD(P)H oxidase mediate angiotensin II-stimulated antioxidant enzymes and mitogen-activated protein kinase activity in the rat hypothalamus.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20101201

• A predictive ligand-based Bayesian model for human drug-induced liver injury.

  Drug metabolism and disposition: the biological fate of chemicals 20101201

• Candesartan attenuates diabetic retinal vascular pathology by restoring glyoxalase-I function.

  Diabetes 20101201

• Impaired relaxation of cerebral arteries in the absence of elevated salt intake in normotensive congenic rats carrying the Dahl salt-sensitive renin gene.

  American journal of physiology. Heart and circulatory physiology 20101201

• Epidermal growth factor receptor transactivation by endogenous vasoactive peptides contributes to hyperproliferation of vascular smooth muscle cells of SHR.

  American journal of physiology. Heart and circulatory physiology 20101201

• Role of the organum vasculosum of the lamina terminalis for the chronic cardiovascular effects produced by endogenous and exogenous ANG II in conscious rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20101201

• Effects of angiotensin III on protein, DNA, and collagen synthesis of neonatal cardiomyocytes and cardiac fibroblasts in vitro.

  Journal of cardiovascular pharmacology and therapeutics 20101201

• Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independent effects?

  Clinical and experimental pharmacology & physiology 20101201

• Targeted disruption of guanylyl cyclase-A/natriuretic peptide receptor-A gene provokes renal fibrosis and remodeling in null mutant mice: role of proinflammatory cytokines.

  Endocrinology 20101201

• Comparison of angiotensin II type 1-receptor blockers to regress pressure overload-induced cardiac hypertrophy in mice.

  Hypertension research : official journal of the Japanese Society of Hypertension 20101201

• Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction.

  Nature genetics 20101201

• Drug-drug interactions that reduce the formation of pharmacologically active metabolites: a poorly understood problem in clinical practice.

  Journal of internal medicine 20101201

• Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement.

  Diabetes care 20101201

• Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement executive summary.

  Diabetes care 20101201

• Resistant hypertension responding to change from furosemide to thiazide: understanding calcium channel blocker-related edema.

  Journal of clinical hypertension (Greenwich, Conn.) 20101201

• Distinct effects of intravascular and extravascular angiotensin II on cerebrovascular circulation of newborn pigs.

  Experimental biology and medicine (Maywood, N.J.) 20101201

• [Pharmacokinetic drug interactions by herbal drugs: Critical evaluation and clinical relevance].

  Wiener medizinische Wochenschrift (1946) 20101201

• Effect of Lacidipine on Blood Pressure and Endothelial Function in Mild-to-Moderate Essential Hypertension Patients With Diabetes in Korea.

  Korean circulation journal 20101201

• Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.

  Healthcare informatics research 20101201

• Left atrial and left atrial appendage systolic function in patients with post-myocardial distal blocks.

  Archives of medical science : AMS 20101201

• Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studies.

  Science translational medicine 20101124

• Nox2 NADPH oxidase promotes pathologic cardiac remodeling associated with Doxorubicin chemotherapy.

  Cancer research 20101115

• Combined effect of polarity and pH on the chromatographic behavior of some angiotensin II receptor antagonists and optimization of their determination in pharmaceutical dosage forms.

  Journal of pharmaceutical and biomedical analysis 20101102

• [Effect of telmisartan on tubulointerstitial injury and expression of PPARγ in rat renal tissue of IgA nephropathy model].

  Zhonghua yi xue za zhi 20101102

• A 52-week prospective, cohort study of the effects of losartan with or without hydrochlorothiazide (HCTZ) in hypertensive patients with metabolic syndrome.

  Journal of human hypertension 20101101

• Telmisartan regresses left ventricular hypertrophy in caveolin-1-deficient mice.

  Laboratory investigation; a journal of technical methods and pathology 20101101

• Angiotensin II inhibits the electrogenic Na+/HCO3- cotransport of cat cardiac myocytes.

  Journal of molecular and cellular cardiology 20101101

• Impact of baseline renal function on the efficacy and safety of aliskiren added to losartan in patients with type 2 diabetes and nephropathy.

  Diabetes care 20101101

• Adenoviral inhibition of AT1a receptors in the paraventricular nucleus inhibits acute increases in mean arterial blood pressure in the rat.

  American journal of physiology. Regulatory, integrative and comparative physiology 20101101

• Obesity-related cardiovascular risk factors after weight loss: a clinical trial comparing gastric bypass surgery and intensive lifestyle intervention.

  European journal of endocrinology 20101101

• The role of blood pressure variability in the development of nephropathy in type 1 diabetes.

  Diabetes care 20101101

• The role of renin-angiotensin agents in altering the natural history of type 2 diabetes mellitus.

  Current cardiology reports 20101101

• Nuclear angiotensin-(1-7) receptor is functionally coupled to the formation of nitric oxide.

  American journal of physiology. Renal physiology 20101101

• Evaluating 24-h antihypertensive efficacy by the smoothness index: a meta-analysis of an ambulatory blood pressure monitoring database.

  Journal of hypertension 20101101

• Different effects of aliskiren and losartan on fibrinolysis and insulin sensitivity in hypertensive patients with metabolic syndrome.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20101101

• Addition of losartan to angiotensin-converting enzyme inhibitors improves insulin resistance in patients with chronic heart failure treated without β-blockers.

  Circulation journal : official journal of the Japanese Circulation Society 20101101

• Impaired flow-induced dilation of coronary arterioles of dogs fed a low-salt diet: roles of ANG II, PKC, and NAD(P)H oxidase.

  American journal of physiology. Heart and circulatory physiology 20101101

• CYP4A2-induced hypertension is 20-hydroxyeicosatetraenoic acid- and angiotensin II-dependent.

  Hypertension (Dallas, Tex. : 1979) 20101101

• Hypothalamic SOCS-3 expression and the effect of intracerebroventricular angiotensin II injection on water intake and renal sodium handling in SHR.

  The journal of physiological sciences : JPS 20101101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Immobilization stress induces endothelial dysfunction by oxidative stress via the activation of the angiotensin II/its type I receptor pathway.

  Atherosclerosis 20101101

• Inhibition of renin-angiotensin system affects prognosis of advanced pancreatic cancer receiving gemcitabine.

  British journal of cancer 20101101

• [Role of angiontensin receptors in remodeling perivascular nerves].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20101101

• Angiotensin-2 receptors (AT1-R and AT2-R), new prognostic factors for renal clear-cell carcinoma?

  British journal of cancer 20101101

• Strategies for initial management of hypertension.

  The Indian journal of medical research 20101101

• Congestive heart failure in Indians: how do we improve diagnosis & management?

  The Indian journal of medical research 20101101

• Diabetes & coronary heart disease: current perspectives.

  The Indian journal of medical research 20101101

• Effect of the AT₁ receptor antagonist losartan on diurnal variation in pain threshold in spontaneously hypertensive rats.

  Methods and findings in experimental and clinical pharmacology 20101101

• [Effect of Qindan Capsule on expression of vascular adventitial collagen I and III in old spontaneous hypertensive rats].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20101101

• Role of differential signaling pathways and oxidative stress in diabetic cardiomyopathy.

  Current cardiology reviews 20101101

• Modulation of Gi Proteins in Hypertension: Role of Angiotensin II and Oxidative Stress.

  Current cardiology reviews 20101101

• Aliskiren: a review of its use as monotherapy and as combination therapy in the management of hypertension.

  Drugs 20101022

• CORD: COmparison of Recommended Doses of ace inhibitors and angiotensin II receptor blockers.

  International journal of cardiology 20101008

• Erythropoietin is reduced by combination of diuretic therapy and RAAS blockade in proteinuric renal patients with preserved renal function.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101001

• Angiotensin II/angiotensin II type I receptor (AT1R) signaling promotes MCF-7 breast cancer cells survival via PI3-kinase/Akt pathway.

  Journal of cellular physiology 20101001

• Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: a randomized, double-blind, placebo-controlled, phase 3 trial.

  Diabetes care 20101001

• Interactions among related genes of renin-angiotensin system associated with type 2 diabetes.

  Diabetes care 20101001

• Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries.

  American journal of physiology. Heart and circulatory physiology 20101001

• Exercise training combined with angiotensin II receptor blockade reduces oxidative stress after myocardial infarction in rats.

  Experimental physiology 20101001

• Persistent antihypertensive effect of aliskiren is accompanied by reduced proteinuria and normalization of glomerular area in Ren-2 transgenic rats.

  American journal of physiology. Renal physiology 20101001

• A small difference in the molecular structure of angiotensin II receptor blockers induces AT₁ receptor-dependent and -independent beneficial effects.

  Hypertension research : official journal of the Japanese Society of Hypertension 20101001

• Blockade of endothelial-mesenchymal transition by a Smad3 inhibitor delays the early development of streptozotocin-induced diabetic nephropathy.

  Diabetes 20101001

• Is the presence of microalbuminuria a relevant marker of kidney disease?

  Current hypertension reports 20101001

• Angiotensin II enhances connecting tubule glomerular feedback.

  Hypertension (Dallas, Tex. : 1979) 20101001

• Moment-to-moment characteristics of the relationship between arterial pressure and renal interstitial hydrostatic pressure.

  Hypertension (Dallas, Tex. : 1979) 20101001

• Antihypertensive and antiarrhythmic properties of a para-hydroxy[bis(ortho-morpholinylmethyl)]phenyl-1,4-DHP compound: comparison with other compounds of the same kind and relationship with logP values.

  European journal of medicinal chemistry 20101001

• Role of the second disulfide bridge (Cys(18)-Cys(274)) in stabilizing the inactive AT₁ receptor.

  Biological chemistry 20101001

• Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.

  The Journal of clinical investigation 20101001

• Prognostic significance of left ventricular diastolic dysfunction in patients with left ventricular hypertrophy and systemic hypertension (the LIFE Study).

  The American journal of cardiology 20101001

• The effect of anti-hypertensive drugs on the obstructive pancreatitis in rats.

  Acta cirurgica brasileira 20101001

• Use of a tunneling technique to achieve a lower defibrillation threshold during implantable cardioverter defibrillator implantation via the right subclavian vein.

  Journal of Korean medical science 20101001

• Increasing the doses of both diuretics and angiotensin receptor blockers is beneficial in subjects with uncontrolled systolic hypertension.

  The Canadian journal of cardiology 20101001

• Losartan Inhibits Vascular Smooth Muscle Cell Proliferation through Activation of AMP-Activated Protein Kinase.

  The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20101001

• Paraganglioma--a case of secondary hypertension.

  Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20101001

• Ninety-seven Years Old Hispanic Male With Mantle Cell Lymphoma.

  Journal of clinical medicine research 20101001

• Angiotensin II type 1 receptor-dependent oxidative stress mediates endothelial dysfunction in type 2 diabetic mice.

  Antioxidants & redox signaling 20100915

• Superoxide scavenging in the rostral ventrolateral medulla blunts the pressor response to peripheral chemoreflex activation.

  Brain research 20100910

• Comparison of the influence of angiotensin-converting enzyme inhibitor lisinopril and angiotensin II receptor antagonist losartan in patients with idiopathic membranous nephropathy and nephrotic syndrome.

  Scandinavian journal of urology and nephrology 20100901

• Mechanisms underlying the losartan treatment-induced improvement in the endothelial dysfunction seen in mesenteric arteries from type 2 diabetic rats.

  Pharmacological research 20100901

• Haemochromatosis genotype and iron overload: association with hypertension and left ventricular hypertrophy.

  Journal of internal medicine 20100901

• Simvastatin reduces pressor response to centrally administered angiotensin II.

  American journal of hypertension 20100901

• Effects of the angiotensin II receptor blocker losartan on the monocyte expression of biglycan in hypertensive patients.

  Clinical and experimental pharmacology & physiology 20100901

• Angiotensin II induces C-reactive protein expression through ERK1/2 and JNK signaling in human aortic endothelial cells.

  Atherosclerosis 20100901

• Interaction between vasopressin and angiotensin II in vivo and in vitro: effect on aquaporins and urine concentration.

  American journal of physiology. Renal physiology 20100901

• Angiotensin AT1 receptor activation mediates high glucose-induced epithelial-mesenchymal transition in renal proximal tubular cells.

  Clinical and experimental pharmacology & physiology 20100901

• All-cause and cardiovascular mortality in relation to changing heart rate during treatment of hypertensive patients with electrocardiographic left ventricular hypertrophy.

  European heart journal 20100901

• An efficient synthesis of a rationally designed 1,5 disubstituted imidazole AT(1) angiotensin II receptor antagonist: reorientation of imidazole pharmacophore groups in losartan reserves high receptor affinity and confirms docking studies.

  Journal of computer-aided molecular design 20100901

• Intermittent hypoxia increases arterial blood pressure in humans through a Renin-Angiotensin system-dependent mechanism.

  Hypertension (Dallas, Tex. : 1979) 20100901

• Clinically significant CYP2C inhibition by noscapine but not by glucosamine.

  Clinical pharmacology and therapeutics 20100901

• Chart review of patients on valsartan-based single-pill combinations vs. ARB-based free combinations for BP goal achievement.

  Current medical research and opinion 20100901

• Postmenopausal hypertension: role of the Renin-Angiotensin system.

  Hypertension (Dallas, Tex. : 1979) 20100901

• Losartan reduces mortality in a genetic model of heart failure.

  Naunyn-Schmiedeberg's archives of pharmacology 20100901

• Effectiveness, safety and cost of drug substitution in hypertension.

  British journal of clinical pharmacology 20100901

• Resveratrol modulates drug- and carcinogen-metabolizing enzymes in a healthy volunteer study.

  Cancer prevention research (Philadelphia, Pa.) 20100901

• Angiotensin receptor type 1 antagonists protect against neuronal injury induced by oxygen-glucose depletion.

  British journal of pharmacology 20100901

• [Regeneration of perivascular nerve and role of angiotensin receptors].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20100901

• TGF-β signaling in aortic aneurysm: another round of controversy.

  Journal of genetics and genomics = Yi chuan xue bao 20100901

• Pharmacokinetics of a losartan potassium released from a transdermal therapeutic system for the treatment of hypertension.

  Die Pharmazie 20100901

• How to avoid discontinuation of antihypertensive treatment: The experience in São Paulo, Brazil.

  Clinics (Sao Paulo, Brazil) 20100901

• Acquired factor VIII deficiency after consuming the dried gallbladder of a cobra, Naja naja.

  The Korean journal of hematology 20100901

• [The normalized smoothness index and parametric population RDH index of losartan in patients with newly diagnosed hypertension and metabolic syndrome].

  Vnitrni lekarstvi 20100901

• [The HEAAL study].

  Giornale italiano di cardiologia (2006) 20100901

• In dystrophic hamsters losartan affects control of ventilation and dopamine D1 receptor density.

  Respiratory physiology & neurobiology 20100831

• Effects of coenzyme Q10 supplementation on activities of selected antioxidative enzymes and lipid peroxidation in hypertensive patients treated with indapamide. A pilot study.

  Archives of medical science : AMS 20100830

• Angiotensin AT1 receptor antagonists enhance the anticonvulsant action of valproate in the mouse model of maximal electroshock.

  European journal of pharmacology 20100825

• Inhibition of the renin-angiotensin system prevents seizures in a rat model of epilepsy.

  Clinical science (London, England : 1979) 20100817

• Characterization of new PPARgamma agonists: benzimidazole derivatives-importance of positions 5 and 6, and computational studies on the binding mode.

  Bioorganic & medicinal chemistry 20100815

• Comparison of the efficacy of candesartan and losartan: a meta-analysis of trials in the treatment of hypertension.

  Journal of human hypertension 20100801

• Central fatigue induced by losartan involves brain serotonin and dopamine content.

  Medicine and science in sports and exercise 20100801

• Effectiveness of combination of losartan potassium and doxycycline versus single-drug treatments in the secondary prevention of thoracic aortic aneurysm in Marfan syndrome.

  The Journal of thoracic and cardiovascular surgery 20100801

• Astroglia are a possible cellular substrate of angiotensin(1-7) effects in the rostral ventrolateral medulla.

  Cardiovascular research 20100801

• Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9.

  European journal of clinical pharmacology 20100801

• Serum uric acid is associated with new-onset diabetes in hypertensive patients with left ventricular hypertrophy: The LIFE Study.

  American journal of hypertension 20100801

• Reduction of fibrosis-related arrhythmias by chronic renin-angiotensin-aldosterone system inhibitors in an aged mouse model.

  American journal of physiology. Heart and circulatory physiology 20100801

• Angiotensin II-induced reduction in body mass is Ang II receptor mediated in association with elevated corticosterone.

  Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20100801

• Angiotensin II induces hyperresponsiveness of bronchial smooth muscle via an activation of p42/44 ERK in rats.

  Pflugers Archiv : European journal of physiology 20100801

• Losartan: the dose does it.

  Expert opinion on pharmacotherapy 20100801

• Low dose of telmisartan prevents ischemic brain damage with peroxisome proliferator-activated receptor-gamma activation in diabetic mice.

  Journal of hypertension 20100801

• Losartan inhibits LPS-induced inflammatory signaling through a PPARgamma-dependent mechanism in human THP-1 macrophages.

  Hypertension research : official journal of the Japanese Society of Hypertension 20100801

• Regulation of the renin expression in the retinal pigment epithelium by systemic stimuli.

  American journal of physiology. Renal physiology 20100801

• The impact of ANG II and IV on INS-1 cells and on blood glucose and plasma insulin.

  Journal of receptor and signal transduction research 20100801

• A low concentration of ouabain (0.18 microg/kg) enhances hypertension in spontaneously hypertensive rats by inhibiting the Na+ pump and activating the renin-angiotensin system.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20100801

• Therapeutic effects of vitamin D analogs on cardiac hypertrophy in spontaneously hypertensive rats.

  The American journal of pathology 20100801

• Comparison of different measures of urinary protein excretion for prediction of renal events.

  Journal of the American Society of Nephrology : JASN 20100801

• Cost-effectiveness of interventions to prevent and control diabetes mellitus: a systematic review.

  Diabetes care 20100801

• Are individuals with diabetes seeing better?: a long-term epidemiological perspective.

  Diabetes 20100801

• Losartan associated anaphylaxis and angioneurotic oedema.

  JPMA. The Journal of the Pakistan Medical Association 20100801

• Losartan attenuates vascular remodeling of the aorta in spontaneously hypertensive rats and the underlying mechanism.

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100801

• Successful Percutaneous Renal Artery Angioplasty and Stenting for Acute Oliguric Renal Failure in a Solitary Functioning Kidney Caused by Takayasu's Arteritis.

  Korean circulation journal 20100801

• [Aortic pulse wave velocity in patients with metabolic syndrome and hypertension treated with sartans].

  Vnitrni lekarstvi 20100801

• Losartan and hypertensive children. Another option for a small number of children.

  Prescrire international 20100801

• [Effect of treatment of non-nephrotic syndrome IgA nephropathy with Shenyanning].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20100801

• [Active pharmacosurveillance of patients affiliated to the Colombian general social security/health system].

  Revista de salud publica (Bogota, Colombia) 20100801

• A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk.

  British journal of cancer 20100727

• Antihypertensive activity of Salvia elegans Vahl. (Lamiaceae): ACE inhibition and angiotensin II antagonism.

  Journal of ethnopharmacology 20100720

• A consistency-adjusted alpha-adaptive strategy for sequential testing.

  Statistics in medicine 20100710

• Inhibition of renin-angiotensin system in experimental acute pancreatitis in rats: a new therapeutic target?

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20100701

• Blocking angiotensin II Type 1 receptor triggers apoptotic cell death in human pancreatic cancer cells.

  Pancreas 20100701

• Losartan improved respiratory function and coenzyme Q content in brain mitochondria of young spontaneously hypertensive rats.

  Cellular and molecular neurobiology 20100701

• Different protective actions of losartan and tempol on the renal inflammatory response to acute sodium overload.

  Journal of cellular physiology 20100701

• The renin-angiotensin system mediates hyperoxia-induced collagen production in human lung fibroblasts.

  Free radical biology & medicine 20100701

• Upregulation of AT1R and iNOS in the rostral ventrolateral medulla (RVLM) is essential for the sympathetic hyperactivity and hypertension in the 2K-1C Wistar rat model.

  American journal of hypertension 20100701

• Aliskiren enhances protective effects of valsartan against type 2 diabetic nephropathy in mice.

  Journal of hypertension 20100701

• Greater regression of electrocardiographic left ventricular hypertrophy during hydrochlorothiazide therapy in hypertensive patients.

  American journal of hypertension 20100701

• In-treatment midwall and endocardial fractional shortening predict cardiovascular outcome in hypertensive patients with preserved baseline systolic ventricular function: the Losartan Intervention For Endpoint reduction study.

  Journal of hypertension 20100701

• Angiotensin II signaling through the AT1a and AT1b receptors does not have a role in the development of cerulein-induced chronic pancreatitis in the mouse.

  American journal of physiology. Gastrointestinal and liver physiology 20100701

• RAAS blockade in combination with diuretic therapy increases urine excretion, which in turn increases drinking and thus reduces erythropoietin and proteinuria.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100701

• Sirolimus and everolimus reduce albumin endocytosis in proximal tubule cells via an angiotensin II-dependent pathway.

  Transplant immunology 20100701

• Soluble uric acid increases intracellular calcium through an angiotensin II-dependent mechanism in immortalized human mesangial cells.

  Experimental biology and medicine (Maywood, N.J.) 20100701

• Is hydrochlorothiazide more effective on LVH in nonresponders to losartan than in those to atenolol?

  American journal of hypertension 20100701

• Marfan syndrome and focal segmental glomerulosclerosis: a novel association.

  Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20100701

• Relationship of left atrial enlargement to persistence or development of ECG left ventricular hypertrophy in hypertensive patients: implications for the development of new atrial fibrillation.

  Journal of hypertension 20100701

• Angiotensin-converting enzyme inhibitors and angioedema.

  Allergy, asthma & immunology research 20100701

• Blood pressure and medication during long-term antihypertensive therapy based on morning home SBP in hypertensive patients: Hypertension Control Based on Home Systolic Pressure (HOSP) substudy.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20100701

• The antioxidant effect of angiotensin II receptor blocker, losartan, in streptozotocin-induced diabetic rats.

  Translational research : the journal of laboratory and clinical medicine 20100701

• Effects of myricetin, an antioxidant, on the pharmacokinetics of losartan and its active metabolite, EXP-3174, in rats: possible role of cytochrome P450 3A4, cytochrome P450 2C9 and P-glycoprotein inhibition by myricetin.

  The Journal of pharmacy and pharmacology 20100701

• Anti-hypertensive drugs have different effects on ventricular hypertrophy regression.

  Clinics (Sao Paulo, Brazil) 20100701

• Effectiveness of barnidipine 10 or 20 mg plus losartan 50-mg combination versus losartan 100-mg monotherapy in patients with essential hypertension not controlled by losartan 50-mg monotherapy: A 12-week, multicenter, randomized, open-label, parallel-group study.

  Clinical therapeutics 20100701

• Pharmacokinetics and bioequivalence evaluation of two losartan potassium 50-mg tablets: A single-dose, randomized-sequence, open-label, two-way crossover study in healthy Chinese male volunteers.

  Clinical therapeutics 20100701

• Fixed-dose telmisartan/hydrochlorothiazide in comparison with losartan/hydrochlorothiazide in decreasing serum hepatocyte growth factor and improving endothelial dysfunction in hypertensive patients.

  International heart journal 20100701

• Generic ARBs are coming.

  Harvard heart letter : from Harvard Medical School 20100701

• Mechanical stress-evoked but angiotensin II-independent activation of angiotensin II type 1 receptor induces cardiac hypertrophy through calcineurin pathway.

  Biochemical and biophysical research communications 20100625

• Mechanical stretch induces nerve sprouting in rat sympathetic neurocytes.

  Autonomic neuroscience : basic & clinical 20100624

• Angiotensin II and the ERK pathway mediate the induction of myocardin by hypoxia in cultured rat neonatal cardiomyocytes.

  Clinical science (London, England : 1979) 20100622

• Management of varices in cirrhosis.

  The New England journal of medicine 20100617

• Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition.

  Bioorganic & medicinal chemistry 20100615

• Hypercholesterolemia modifies angiotensin II desensitisation and cross talk between alpha(1)-adrenoceptor and angiotensin AT(1) receptor in rabbit aorta.

  European journal of pharmacology 20100610

• Transforming growth factor beta1 mediates apoptotic activity of angiotensin II type I receptor blocker on prostate epithelium in vitro.

  The Prostate 20100601

• Combined vitamin D analog and AT1 receptor antagonist synergistically block the development of kidney disease in a model of type 2 diabetes.

  Kidney international 20100601

• Repeated administration of angiotensin II reduces its dipsogenic effect without affecting saline intake.

  Experimental physiology 20100601

• Hypertensive effects of central angiotensin II infusion and restraint stress are reduced with age.

  Journal of hypertension 20100601

• Effect of ACE2 and angiotensin-(1-7) in a mouse model of early chronic kidney disease.

  American journal of physiology. Renal physiology 20100601

• Hypertension study in anaesthetized rabbits: protocol proposal for AT1 antagonists screening.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20100601

• Economic evaluation of four angiotensin II receptor blockers in the treatment of hypertension.

  Current medical research and opinion 20100601

• Vitamin D receptor attenuates renal fibrosis by suppressing the renin-angiotensin system.

  Journal of the American Society of Nephrology : JASN 20100601

• Hotline update of clinical trials and registries presented at the American College of Cardiology Congress 2010: ACCORD, INVEST, NAVIGATOR, RACE II, SORT OUT III, CSP-474, DOSE, ASPIRE and more.

  Clinical research in cardiology : official journal of the German Cardiac Society 20100601

• Upregulation of renal sodium transporters in D5 dopamine receptor-deficient mice.

  Hypertension (Dallas, Tex. : 1979) 20100601

• Lack of regression of left ventricular hypertrophy is associated with higher incidence of revascularization in hypertension: The LIFE Study.

  Blood pressure 20100601

• A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity.

  Pharmacogenetics and genomics 20100601

• In-treatment reduced left atrial diameter during antihypertensive treatment is associated with reduced new-onset atrial fibrillation in hypertensive patients with left ventricular hypertrophy: The LIFE Study.

  Blood pressure 20100601

• Reduction of inducible nitric oxide synthase via angiotensin receptor blocker prevents the oxidative retinal damage in diabetic hypertensive rats.

  Current eye research 20100601

• Are vitamin D receptor agonists like angiotensin-converting enzyme inhibitors without side effects?

  Kidney international 20100601

• Are coronary revascularization and myocardial infarction a homogeneous combined endpoint in hypertension trials? The Losartan Intervention For Endpoint reduction in hypertension study.

  Journal of hypertension 20100601

• Ambulatory monitoring of systolic hypertension in the elderly: Eprosartan/hydrochlorothiazide compared with losartan/hydrochlorothiazide (INSIST trial).

  Advances in therapy 20100601

• Angiotensin-(1-9), the product of angiotensin I conversion in platelets, enhances arterial thrombosis in rats.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100601

• Norepinephrine remains increased in the six-minute walking test after heart transplantation.

  Clinics (Sao Paulo, Brazil) 20100601

• Effects of Huanshuai Recipe Oral Liquid on restructuring glomerular microvasculature and expression of vascular endothelial growth factor in subtotal nephrectomized rats.

  Chinese journal of integrative medicine 20100601

• Comparison of the efficacy and tolerability of telmisartan and enalapril in patients of mild to moderate essential hypertension.

  Indian journal of pharmacology 20100601

• Marfan syndrome: clinical manifestations, pathophysiology and new outlook on drug therapy.

  Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20100601

• Simultaneous spectrophotometric determination of losartan potassium, amlodipine besilate and hydrochlorothiazide in pharmaceuticals by chemometric methods.

  Acta pharmaceutica (Zagreb, Croatia) 20100601

• Ambulatory blood pressure, endothelial perturbation, and microvascular complications in type 2 diabetes.

  Danish medical bulletin 20100601

• Losartan attenuates chronic cigarette smoke exposure-induced pulmonary arterial hypertension in rats: possible involvement of angiotensin-converting enzyme-2.

  Toxicology and applied pharmacology 20100515

• Renin-Angiotensin system blockade for diabetic nephropathy prevention.

  The American journal of cardiology 20100515

• Angiotensin II stimulates thick ascending limb NO production via AT(2) receptors and Akt1-dependent nitric-oxide synthase 3 (NOS3) activation.

  The Journal of biological chemistry 20100514

• Prostaglandin E1 for preventing the progression of diabetic kidney disease.

  The Cochrane database of systematic reviews 20100512

• Inhibition of angiotensin II receptor 1 limits tumor-associated angiogenesis and attenuates growth of murine melanoma.

  Cancer chemotherapy and pharmacology 20100501

• Determination of asperosaponin VI in rat plasma by HPLC-ESI-MS and its application to preliminary pharmacokinetic studies.

  Biomedical chromatography : BMC 20100501

• Angiotensin II up-regulates CX3CR1 expression in THP-1 monocytes: impact on vascular inflammation and atherogenesis.

  Journal of thrombosis and thrombolysis 20100501

• Long-term metabolic effects of different doses of niacin-bound chromium on Sprague-Dawley rats.

  Molecular and cellular biochemistry 20100501

• Tumour necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fn14 during cardiac remodelling in rats.

  Acta physiologica (Oxford, England) 20100501

• Fibronectin synthesis by high glucose level mediated proliferation of mouse embryonic stem cells: Involvement of ANG II and TGF-beta1.

  Journal of cellular physiology 20100501

• Chronic AT1 receptor blockade normalizes NMDA-mediated changes in renal sympathetic nerve activity and NR1 expression within the PVN in rats with heart failure.

  American journal of physiology. Heart and circulatory physiology 20100501

• Is pulse pressure a predictor of new-onset diabetes in high-risk hypertensive patients?: a subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial.

  Diabetes care 20100501

• Involvement of the renin-angiotensin system in the development of vascular damage in a rat model of arthritis: effect of angiotensin receptor blockers.

  Arthritis and rheumatism 20100501

• Losartan increases NO release in afferent arterioles during regression of L-NAME-induced renal damage.

  American journal of physiology. Renal physiology 20100501

• Does enhanced respiratory-sympathetic coupling contribute to peripheral neural mechanisms of angiotensin II-salt hypertension?

  Experimental physiology 20100501

• Ventilator-induced inflammatory response in lipopolysaccharide-exposed rat lung is mediated by angiotensin-converting enzyme.

  The American journal of pathology 20100501

• Marfan syndrome. Part 2: treatment and management of patients.

  Nature reviews. Cardiology 20100501

• Aldose reductase inhibitor ameliorates renal vascular endothelial growth factor expression in streptozotocin-induced diabetic rats.

  Yonsei medical journal 20100501

• Soluble epoxide hydrolase in atherosclerosis.

  Current atherosclerosis reports 20100501

• Is losartan the true panacea for aneurysm disease? PRO.

  Cardiology clinics 20100501

• Is losartan the true panacea for aneurysm disease? CON.

  Cardiology clinics 20100501

• Editorial comment: losartan-based medical therapy for aneurysm disease.

  Cardiology clinics 20100501

• The effects of lumiracoxib 100 mg once daily vs. ibuprofen 600 mg three times daily on the blood pressure profiles of hypertensive osteoarthritis patients taking different classes of antihypertensive agents.

  International journal of clinical practice 20100501

• Comparing angiotensin II receptor blockers on benefits beyond blood pressure.

  Advances in therapy 20100501

• Rationale and design of a randomized clinical trial (Marfan Sartan) of angiotensin II receptor blocker therapy versus placebo in individuals with Marfan syndrome.

  Archives of cardiovascular diseases 20100501

• Diabetic nephropathy and chronic kidney disease at a busy diabetes clinic: a study of outpatient care and suggestions for improved care pathways at a subspecialty specialist diabetic renal clinic.

  The Ulster medical journal 20100501

• The Role of Asymmetric Dimethylarginine (ADMA) in Endothelial Dysfunction and Cardiovascular Disease.

  Current cardiology reviews 20100501

• Chronic intermittent hypoxia augments chemoreflex control of sympathetic activity: role of the angiotensin II type 1 receptor.

  Respiratory physiology & neurobiology 20100415

• Effects of atenolol or losartan on fibrinolysis and von Willebrand factor in hypertensive patients with left ventricular hypertrophy.

  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20100401

• Recoverability of renal function after relief of chronic partial unilateral ureteral obstruction: study of the effect of angiotensin receptor blocker (losartan).

  Urology 20100401

• Losartan prevents portal hypertension-induced, redox-mediated endothelial dysfunction in the mesenteric artery in rats.

  Gastroenterology 20100401

• Effects of losartan vs candesartan in reducing cardiovascular events in the primary treatment of hypertension.

  Journal of human hypertension 20100401

• Sympathoinhibitory effect of statins in chronic heart failure.

  Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20100401

• Short-term angiotensin-1 receptor antagonism in type 2 diabetic Goto-Kakizaki rats normalizes endothelin-1-induced mesenteric artery contraction.

  Peptides 20100401

• One-year effectiveness and safety of open-label losartan/hydrochlorothiazide combination therapy in Japanese patients with hypertension uncontrolled with ARBs or ACE inhibitors.

  Hypertension research : official journal of the Japanese Society of Hypertension 20100401

• Effect of Renin-Angiotensin system blockade on insulin resistance and inflammatory parameters in patients with impaired glucose tolerance.

  Diabetes care 20100401

• Heart failure events with rosiglitazone in type 2 diabetes: data from the RECORD clinical trial.

  European heart journal 20100401

• Antiapoptotic effect of angiotensin-II type-1 receptor blockade in renal tubular cells of hyperoxaluric rats.

  Urological research 20100401

• Angiotensin-(1-7) and angiotension II in the rostral ventrolateral medulla modulate the cardiac sympathetic afferent reflex and sympathetic activity in rats.

  Pflugers Archiv : European journal of physiology 20100401

• Telmisartan prevents weight gain and obesity through activation of peroxisome proliferator-activated receptor-delta-dependent pathways.

  Hypertension (Dallas, Tex. : 1979) 20100401

• Pharmacodynamics of a losartan transdermal system for the treatment of hypertension.

  Drug development and industrial pharmacy 20100401

• AT1 receptor blockade prevents the increase in blood pressure and the augmentation of intrarenal ANG II levels in hypertensive Cyp1a1-Ren2 transgenic rats fed with a high-salt diet.

  The American journal of the medical sciences 20100401

• Serological predictors for the recurrence of atrial fibrillation after electrical cardioversion.

  Korean circulation journal 20100401

• Enhanced effect of losartan and rosuvastatin on neointima hyperplasia.

  Archives of pharmacal research 20100401

• Curcumin reduces angiotensin II-mediated cardiomyocyte growth via LOX-1 inhibition.

  Journal of cardiovascular pharmacology 20100401

• Blockade of calcium channels and AT1 receptor prevents the hypertensive effect of calcilytic NPS 2143 in rats.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100401

• Evidence for the involvement of NADPH oxidase in ischemia/reperfusion-induced gastric damage via angiotensin II.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100401

• Utilization of cardiovascular drugs in Zagreb 2001-2005.

  Acta cardiologica 20100401

• Angiotensin II type 1 receptor gene polymorphism could influence renoprotective response to losartan treatment in type 1 diabetic patients with high urinary albumin excretion rate.

  Vojnosanitetski pregled 20100401

• Effects of mineralocorticoid and angiotensin II receptor blockers on proteinuria and glomerular podocyte protein expression in a model of minimal change nephrotic syndrome.

  Nephrology (Carlton, Vic.) 20100401

• Establishment of an in vivo model facilitates B2 receptor protein maturation and heterodimerization.

  Integrative biology : quantitative biosciences from nano to macro 20100401

• Application of direct renin inhibition to chronic kidney disease.

  Cardiovascular drugs and therapy 20100401

• Comparative study of hydrochlorothiazide and indapamide on the anti-atherogenic potential of losartan in cholesterol fed rat.

  Bangladesh Medical Research Council bulletin 20100401

• Importance of angiotensinergic mechanisms for the pressor response to l-glutamate into the rostral ventrolateral medulla.

  Brain research 20100331

• FURO/CAP: a protocol for sodium intake sensitization.

  Physiology & behavior 20100330

• High-dose versus low-dose losartan in patients with heart failure.

  Lancet (London, England) 20100327

• High-dose versus low-dose losartan in patients with heart failure.

  Lancet (London, England) 20100327

• Telmisartan improves vascular function independently of metabolic and antihypertensive effects in hypertensive subjects with impaired glucose tolerance.

  International journal of cardiology 20100318

• Simultaneous determination of irbesartan and hydrochlorothiazide in human plasma using HPLC coupled with tandem mass spectrometry: Application to bioequivalence studies.

  Journal of pharmaceutical and biomedical analysis 20100311

• Structural basis for platelet antiaggregation by angiotensin II type 1 receptor antagonist losartan (DuP-753) via glycoprotein VI.

  Journal of medicinal chemistry 20100311

• Angiotensin II infusion promotes ascending aortic aneurysms: attenuation by CCR2 deficiency in apoE-/- mice.

  Clinical science (London, England : 1979) 20100309

• Effect of acute stress on sexual behavior in female rats: participation of the central angiotensinergic system.

  Behavioural brain research 20100305

• Angiotensin II inhibits neuronal nitric oxide synthase activation through the ERK1/2-RSK signaling pathway to modulate central control of blood pressure.

  Circulation research 20100305

• Na(+)-ATPase in spontaneous hypertensive rats: possible AT(1) receptor target in the development of hypertension.

  Biochimica et biophysica acta 20100301

• Two flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations.

  The Journal of pharmacology and experimental therapeutics 20100301

• Cardiovascular interactions between losartan and fructose in mice.

  Journal of cardiovascular pharmacology and therapeutics 20100301

• Differences in pharmacology and their translation into differences in clinical efficacy--a comparison of the renin angiotensin blocking agents irbesartan and losartan.

  Expert opinion on pharmacotherapy 20100301

• Angiotensin type 2 receptor actions contribute to angiotensin type 1 receptor blocker effects on kidney fibrosis.

  American journal of physiology. Renal physiology 20100301

• Downregulated Kv4.3 expression in the RVLM as a potential mechanism for sympathoexcitation in rats with chronic heart failure.

  American journal of physiology. Heart and circulatory physiology 20100301

• Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats.

  Hepatology (Baltimore, Md.) 20100301

• Protection of retinal vasculature by losartan against apoptosis and vasculopathy in rats with spontaneous hypertension.

  Journal of hypertension 20100301

• NOX2 is the primary source of angiotensin II-induced superoxide in the macula densa.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100301

• Effects of the AT(1) receptor blocker losartan and the calcium channel blocker benidipine on the accumulation of lipids in the kidney of a rat model of metabolic syndrome.

  Hypertension research : official journal of the Japanese Society of Hypertension 20100301

• Randomized, double-blind, controlled study of losartan in children with proteinuria.

  Clinical journal of the American Society of Nephrology : CJASN 20100301

• Alterations of cardiac ERK1/2 expression and activity due to volume overload were attenuated by the blockade of RAS.

  Journal of cardiovascular pharmacology and therapeutics 20100301

• Receptor activity-modifying protein 1 increases baroreflex sensitivity and attenuates Angiotensin-induced hypertension.

  Hypertension (Dallas, Tex. : 1979) 20100301

• Comparative vascular and renal tubular effects of angiotensin II receptor blockers combined with a thiazide diuretic in humans.

  Journal of hypertension 20100301

• Year in review in Intensive Care Medicine 2009: II. Neurology, cardiovascular, experimental, pharmacology and sedation, communication and teaching.

  Intensive care medicine 20100301

• Diabetes-associated alterations in volatile anesthetic actions on contractile response to norepinephrine in isolated mesenteric resistance arteries.

  Anesthesiology 20100301

• Blood pressure and diabetic nephropathy.

  Diabetes care 20100301

• Review of the AMADEO study: reducing proteinuria in patients with diabetic nephropathy with telmisartan versus losartan. Commentary.

  Postgraduate medicine 20100301

• Where will the next generation of stroke treatments come from?

  PLoS medicine 20100301

• Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters.

  Biopharmaceutics & drug disposition 20100301

• [Effects of Shenqi Jiedu Decoction on expressions of transforming growth factor-beta1, smad2 and smad3 in renal tissues of rats with chronic renal failure induced by adenine].

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20100301

• Role of vasoactive peptides in high glucose-induced increased expression of Gαq/11 proteins and associated signaling in vascular smooth muscle cells.

  Canadian journal of physiology and pharmacology 20100301

• Update on the pharmacological treatment of Alzheimer's disease.

  Current neuropharmacology 20100301

• Recurrent syncope and hypocalcaemic cardiomyopathy as manifestations of Fahr's syndrome.

  Archives of medical science : AMS 20100301

• Hypothyroid dependent myocardial angiotensin receptor trafficking is involved in improved cardiac performance after heat acclimation.

  Life sciences 20100227

• Effects of anti-hypertensive drugs on esophageal body contraction.

  World journal of gastroenterology 20100227

• The effect of Telmisartan on collagen biosynthesis depends on the status of estrogen activation in breast cancer cells.

  European journal of pharmacology 20100225

• Angiotensin II induces a region-specific hyperplasia of the ascending aorta through regulation of inhibitor of differentiation 3.

  Circulation research 20100219

• Angiotensin II type 2 receptor mediated angiotensin II and high glucose induced decrease in renal prorenin/renin receptor expression.

  Molecular and cellular endocrinology 20100205

• Cost-effectiveness of antihypertensive treatment in patients 80 years of age or older in Switzerland: an analysis of the HYVET study from a Swiss perspective.

  Journal of human hypertension 20100201

• Expression and distribution of NADPH oxidase isoforms in human myometrium--role in angiotensin II-induced hypertrophy.

  Biology of reproduction 20100201

• Effect of direct renin inhibition on renal hemodynamic function, arterial stiffness, and endothelial function in humans with uncomplicated type 1 diabetes: a pilot study.

  Diabetes care 20100201

• Angiotensin II exerts glucose-dependent effects on Kv currents in mouse pancreatic beta-cells via angiotensin II type 2 receptors.

  American journal of physiology. Cell physiology 20100201

• Human recombinant ACE2 reduces the progression of diabetic nephropathy.

  Diabetes 20100201

• Curcumin reduces angiotensin II-mediated cardiomyocyte growth via LOX-1 inhibition.

  Journal of cardiovascular pharmacology 20100201

• Angiotensin II type 1 and type 2 receptors regulate basal skeletal muscle microvascular volume and glucose use.

  Hypertension (Dallas, Tex. : 1979) 20100201

• Innovations in aortic disease: the ascending aorta and aortic arch.

  Journal of cardiothoracic and vascular anesthesia 20100201

• Building a tiered approach to in vitro predictive toxicity screening: a focus on assays with in vivo relevance.

  Combinatorial chemistry & high throughput screening 20100201

• Glutamatergic receptor activation in the rostral ventrolateral medulla mediates the sympathoexcitatory response to hyperinsulinemia.

  Hypertension (Dallas, Tex. : 1979) 20100201

• Effect of ACE insertion/deletion and 12 other polymorphisms on clinical outcomes and response to treatment in the LIFE study.

  Pharmacogenetics and genomics 20100201

• HEAAL: the final chapter in the story of angiotensin receptor blockers in heart failure--lessons learnt from a decade of trials.

  European journal of heart failure 20100201

• Clinical trials update from the American Heart Association meeting 2009: HEAAL, FAIR-HF, J-CHF, HeartMate II, PACE and a meta-analysis of dose-ranging studies of beta-blockers in heart failure.

  European journal of heart failure 20100201

• Relationship of blood pressure to retinal vessel diameter in type 1 diabetes mellitus.

  Archives of ophthalmology (Chicago, Ill. : 1960) 20100201

• Comparative effects of losartan and nifedipine therapy on exercise capacity, Doppler echocardiographic parameters and endothelin levels in patients with secondary pulmonary hypertension.

  Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20100201

• Losartan and nifedipine therapy in patients with secondary pulmonary hypertension.

  Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20100201

• Effects of eprosartan on diastolic function and neurohormones in patients with hypertension and diastolic dysfunction.

  Cardiovascular drugs and therapy 20100201

• Dual blockade of the renin-angiotensin-aldosterone system is safe and effective in reducing albuminuria in Asian type 2 diabetic patients with nephropathy.

  Singapore medical journal 20100201

• Angiotensin II receptor blocker add-on therapy for low cardiac output in decompensated heart failure.

  Arquivos brasileiros de cardiologia 20100201

• A case of losartan induced angioedema.

  Indian journal of medical sciences 20100201

• Development of swelling/floating gastroretentive drug delivery system based on a combination of hydroxyethyl cellulose and sodium carboxymethyl cellulose for Losartan and its clinical relevance in healthy volunteers with CYP2C9 polymorphism.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100131

• TRPV1 gene deficiency attenuates miniature EPSC potentiation induced by mannitol and angiotensin II in supraoptic magnocellular neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100120

• Mechanism of VEGF expression by high glucose in proximal tubule epithelial cells.

  Molecular and cellular endocrinology 20100115

• Use of multiattribute utility theory for formulary management in a health system.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100115

• Angiotensin II and CRF receptors in the central nucleus of the amygdala mediate hemodynamic response variability to cocaine in conscious rats.

  Brain research 20100114

• Angiotensin II activates JAK2/STAT3 pathway and induces interleukin-6 production in cultured rat brainstem astrocytes.

  Regulatory peptides 20100108

• Angiotensin II type 1 receptor-mediated upregulation of calcineurin activity underlies impairment of cardioprotective signaling in diabetic hearts.

  Circulation research 20100108

• Are there effects of renin-angiotensin system antagonists beyond blood pressure control?

  The American journal of cardiology 20100104

• Interaction of angiotensin II type 1 receptor blockers with P-gp substrates in Caco-2 cells and hMDR1-expressing membranes.

  Life sciences 20100102

• Modulation of hepatic fibrosis by c-Jun-N-terminal kinase inhibition.

  Gastroenterology 20100101

• Role of the median preoptic nucleus in the chronic hypotensive effect of losartan in sodium-replete normal rats.

  Clinical and experimental pharmacology & physiology 20100101

• Angiotensin II signaling via type 2 receptors in a human model of vascular hyporeactivity: implications for hypertension.

  Journal of hypertension 20100101

• Angiotensin II enhances hyperpolarization-activated currents in rat aortic baroreceptor neurons: involvement of superoxide.

  American journal of physiology. Cell physiology 20100101

• Myoglobin induces vascular cell adhesion molecule-1 expression through c-Src kinase-activator protein-1/nuclear factor-kappaB pathways.

  Nephron. Experimental nephrology 20100101

• Aliskiren monotherapy does not cause paradoxical blood pressure rises: meta-analysis of data from 8 clinical trials.

  Hypertension (Dallas, Tex. : 1979) 20100101

• Effect of cilnidipine vs losartan on cerebral blood flow in hypertensive patients with a history of ischemic stroke: a randomized controlled trial.

  Acta neurologica Scandinavica 20100101

• Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus.

  Hypertension (Dallas, Tex. : 1979) 20100101

• Curcumin attenuates glucose-induced monocyte chemoattractant protein-1 synthesis in aortic endothelial cells by modulating the nuclear factor-kappaB pathway.

  Pharmacology 20100101

• Choosing an angiotensin-receptor blocker: blood pressure lowering, cardiovascular protection or both?

  Future cardiology 20100101

• Medicinal chemistry of drugs used in diabetic cardiomyopathy.

  Current medicinal chemistry 20100101

• Role of caveolin and heat shock protein 70 interaction in the antioxidative effects of an angiotensin II type 1 receptor blocker in spontaneously hypertensive rats proximal tubules.

  Journal of hypertension 20100101

• Caveolin-1 and Hsp70 interaction in microdissected proximal tubules from spontaneously hypertensive rats as an effect of Losartan.

  Journal of hypertension 20100101

• Standards of medical care in diabetes--2010.

  Diabetes care 20100101

• Efficacy and tolerability of a fixed-dose combination of metoprolol extended release/amlodipine in patients with mild-to-moderate hypertension: a randomized, parallel-group, multicentre comparison with losartan plus amlodipine.

  Clinical drug investigation 20100101

• Losartan therapy in adults with Marfan syndrome: study protocol of the multi-center randomized controlled COMPARE trial.

  Trials 20100101

• Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: prospective cohort analysis.

  BMJ (Clinical research ed.) 20100101

• A novel method to adjust efficacy estimates for uptake of other active treatments in long-term clinical trials.

  PloS one 20100101

• Brain natriuretic peptide is related to diastolic dysfunction whereas urinary albumin excretion rate is related to left ventricular mass in asymptomatic type 2 diabetes patients.

  Cardiovascular diabetology 20100101

• Myocardial infarction and stroke associated with diuretic based two drug antihypertensive regimens: population based case-control study.

  BMJ (Clinical research ed.) 20100101

• Cost effectiveness of angiotensin receptor blocker monotherapy in patients with hypertension in the Netherlands: a comparative analysis using clinical trial and drug utilization data.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20100101

• [Protective effect of losartan on insulin secretion function of RIN-m cells against angiotensin II-induced injury and the mechanism].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100101

• Ramipril mitigates radiation-induced impairment of neurogenesis in the rat dentate gyrus.

  Radiation oncology (London, England) 20100101

• [Effect of different doses of losartan on cirrhotic portal hypertensive colopathy in rats].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20100101

• Losartan normalizes endothelium-derived hyperpolarizing factor-mediated relaxation by activating Ca2+-activated K+ channels in mesenteric artery from type 2 diabetic GK rat.

  Journal of pharmacological sciences 20100101

• Management of hyperuricemia in gout: focus on febuxostat.

  Clinical interventions in aging 20100101

• Rationale and design of the ADDITION-Leicester study, a systematic screening programme and randomised controlled trial of multi-factorial cardiovascular risk intervention in people with type 2 diabetes mellitus detected by screening.

  Trials 20100101

• Allergic reaction related to ramipril use: a case report.

  Diabetology & metabolic syndrome 20100101

• Anti-hyperglycemic and anti-hyperlipidemic effects of guava leaf extract.

  Nutrition & metabolism 20100101

• Angiotensin II type 2 receptor signaling significantly attenuates growth of murine pancreatic carcinoma grafts in syngeneic mice.

  BMC cancer 20100101

• Cyclic stretch enhances the expression of toll-like receptor 4 gene in cultured cardiomyocytes via p38 MAP kinase and NF-kappaB pathway.

  Journal of biomedical science 20100101

• Valsartan addition to amlodipine is more effective than losartan addition in hypertensive patients inadequately controlled by amlodipine.

  Vascular health and risk management 20100101

• Inflammatory mediators of hepatic steatosis.

  Mediators of inflammation 20100101

• Internalization of constitutively active N111G MUTANT of AT1 receptor induced by angiotensin II-receptor antagonists candesartan, losartan, and telmisartan: comparison with valsartan.

  Journal of pharmacological sciences 20100101

• Effects of a low-dose antihypertensive diuretic in combination with losartan, telmisartan, or candesartan on serum urate levels in hypertensive patients.

  Arzneimittel-Forschung 20100101

• Controlling hypertension immediately post stroke: a cost utility analysis of a pilot randomised controlled trial.

  Cost effectiveness and resource allocation : C/E 20100101

• Statins, antihypertensive treatment, and blood pressure control in clinic and over 24 hours: evidence from PHYLLIS randomised double blind trial.

  BMJ (Clinical research ed.) 20100101

• [Effect of iron overload on experimental immunological liver injury in rats and the role of angiotensin].

  Wei sheng yan jiu = Journal of hygiene research 20100101

• Protective effects of intranasal losartan in the APP/PS1 transgenic mouse model of Alzheimer disease.

  Rejuvenation research 20100101

• Effect of losartan on vascular function in fructose-fed rats: the role of perivascular adipose tissue.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20100101

• Angiotensin II inhibits insulin-stimulated GLUT4 translocation and Akt activation through tyrosine nitration-dependent mechanisms.

  PloS one 20100101

• Recent achievements in the management of Raynaud's phenomenon.

  Vascular health and risk management 20100101

• Role of valsartan, amlodipine and hydrochlorothiazide fixed combination in blood pressure control: an update.

  Vascular health and risk management 20100101

• Role of inflammation in túbulo-interstitial damage associated to obstructive nephropathy.

  Journal of inflammation (London, England) 20100101

• [Recent clinical evidences of RAS inhibitors on chronic kidney diseases].

  Nihon Jinzo Gakkai shi 20100101

• Autosomal dominant polycystic kidney disease with diffuse proliferative glomerulonephritis - an unusual association: a case report and review of the literature.

  Journal of medical case reports 20100101

• Localization of angiotensin converting enzyme in rabbit cornea and its role in controlling corneal angiogenesis in vivo.

  Molecular vision 20100101

• Pharmacological evaluation of 'Glyoherb': A polyherbal formulation on streptozotocin-induced diabetic rats.

  International journal of diabetes in developing countries 20100101

• The role of renin angiotensin system inhibition in kidney repair.

  Fibrogenesis & tissue repair 20100101

• New standards in hypertension and cardiovascular risk management: focus on telmisartan.

  Vascular health and risk management 20100101

• Advances in the treatment of Raynaud's phenomenon.

  Vascular health and risk management 20100101

• Captopril reduces cardiac inflammatory markers in spontaneously hypertensive rats by inactivation of NF-kB.

  Journal of inflammation (London, England) 20100101

• Association of circulating angiotensin converting enzyme activity with respiratory muscle function in infants.

  Respiratory research 20100101

• From design to implementation--the Joint Asia Diabetes Evaluation (JADE) program: a descriptive report of an electronic web-based diabetes management program.

  BMC medical informatics and decision making 20100101

• On call. I've read your comprehensive discussion of erectile dysfunction, but one aspect is not mentioned: at age 74 (with a new wife, age 70), I can have erections, both with and without Levitra, but I have increasing difficulty achieving difficulty achieving ejaculation. I assume this is related to ED and age, but wonder whether there is a solution. I don't drink or have diabetes. I do have high blood pressure, but it's controlled with Hyzaar and Plendil.

  Harvard men's health watch 20100101

• The estimated GFR, but not the stage of diabetic nephropathy graded by the urinary albumin excretion, is associated with the carotid intima-media thickness in patients with type 2 diabetes mellitus: a cross-sectional study.

  Cardiovascular diabetology 20100101

• Forecasting drug utilization and expenditure in a metropolitan health region.

  BMC health services research 20100101

• Effects of Losartan on expression of connexins at the early stage of atherosclerosis in rabbits.

  International journal of medical sciences 20100101

• Severe hepatic encephalopathy in a patient with liver cirrhosis after administration of angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker combination therapy: a case report.

  Journal of medical case reports 20100101

• Effect of losartan and benzbromarone on the level of human urate transporter 1 mRNA.

  Arzneimittel-Forschung 20100101

• The effect of chronic candesartan therapy on the metabolic profile and renal tissue cytokine levels in the obese Zucker rat.

  Mediators of inflammation 20100101

• Angiotensin II upregulates the expression of placental growth factor in human vascular endothelial cells and smooth muscle cells.

  BMC cell biology 20100101

• Skeletal dysplasias associated with mild myopathy-a clinical and molecular review.

  Journal of biomedicine & biotechnology 20100101

• Rapid cell culture and pre-clinical screening of a transforming growth factor-beta (TGF-beta) inhibitor for orthopaedics.

  BMC musculoskeletal disorders 20100101

• Current cardiac imaging techniques for detection of left ventricular mass.

  Cardiovascular ultrasound 20100101

• Availability, price and affordability of cardiovascular medicines: a comparison across 36 countries using WHO/HAI data.

  BMC cardiovascular disorders 20100101

• Mycophenolic acid area under the curve recovery time following rifampicin withdrawal.

  Indian journal of nephrology 20100101

• Ichthyotic-appearing skin changes associated with childhood morphea, systemic sclerosis, and systemic lupus erythematosus/scleroderma overlap.

  Pediatric dermatology 20100101

• Optimal use of beta-blockers in high-risk hypertension: a guide to dosing equivalence.

  Vascular health and risk management 20100101

• Heart rate control with adrenergic blockade: clinical outcomes in cardiovascular medicine.

  Vascular health and risk management 20100101

• Early brief treatment with losartan plus mycophenolate mofetil provides lasting renoprotection in a renal ablation model.

  American journal of nephrology 20100101

• Accuracy of advanced versus strictly conventional 12-lead ECG for detection and screening of coronary artery disease, left ventricular hypertrophy and left ventricular systolic dysfunction.

  BMC cardiovascular disorders 20100101

• Calcium-sensing receptors regulate cardiomyocyte Ca2+ signaling via the sarcoplasmic reticulum-mitochondrion interface during hypoxia/reoxygenation.

  Journal of biomedical science 20100101

• Maitake mushroom extracts ameliorate progressive hypertension and other chronic metabolic perturbations in aging female rats.

  International journal of medical sciences 20100101

• Use of evidence-based pharmacotherapy after myocardial infarction in Estonia.

  BMC public health 20100101

• Combination therapy in hypertension: An update.

  Diabetology & metabolic syndrome 20100101

• RP-HPLC Method for the Determination of Losartan Potassium and Ramipril in Combined Dosage Form.

  Indian journal of pharmaceutical sciences 20100101

• Spectrophotometric and HPLC methods for simultaneous estimation of amlodipine besilate, losartan potassium and hydrochlorothiazide in tablets.

  Indian journal of pharmaceutical sciences 20100101

• Gene activation regresses atherosclerosis, promotes health, and enhances longevity.

  Lipids in health and disease 20100101

• Thyroid Hormone Increases TGF-beta1 in Cardiomyocytes Cultures Independently of Angiotensin II Type 1 and Type 2 Receptors.

  International journal of endocrinology 20100101

• Synthesis and Supramolecular Structure of a (5-(3-(1H-tetrazol-5-yl)phenyl)-1H-tetrazole) Cobalt Complex.

  Bioinorganic chemistry and applications 20100101

• Despite similar reduction of blood pressure and renal ANG II and ET-1 levels aliskiren but not losartan normalizes albuminuria in hypertensive Ren-2 rats.

  Physiological research 20100101

• Factor XII mutations, estrogen-dependent inherited angioedema, and related conditions.

  Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20100101

• Drug-based therapies for vascular disease in Marfan syndrome: from mouse models to human patients.

  The Mount Sinai journal of medicine, New York 20100101

• Hemi-central retinal artery occlusion in young adults.

  Indian journal of ophthalmology 20100101

• Differences in efficacy and safety of pharmaceutical treatments between men and women: an umbrella review.

  PloS one 20100101

• Comparison of laser Doppler imaging, fingertip lacticemy test, and nailfold capillaroscopy for assessment of digital microcirculation in systemic sclerosis.

  Arthritis research & therapy 20100101

• A hepatitis C-positive patient with new onset of nephrotic syndrome and systemic amyloidosis secondary to common variable immunodeficiency.

  Annals of Saudi medicine 20100101

• Treatment of specific macrovascular beds in patients with diabetes mellitus.

  Osteopathic medicine and primary care 20100101

• Nocturnal blood pressure fall as predictor of diabetic nephropathy in hypertensive patients with type 2 diabetes.

  Cardiovascular diabetology 20100101

• Advanced glycation end products, oxidative stress and diabetic nephropathy.

  Oxidative medicine and cellular longevity 20100101

• Metabolic syndrome, dyslipidemia, hypertension and type 2 diabetes in youth: from diagnosis to treatment.

  Diabetology & metabolic syndrome 20100101

• A comparison of the effects of ramipril and losartan on blood pressure control and left ventricle hypertrophy in patients with autosomal dominant polycystic kidney disease.

  Renal failure 20100101

• Ang II enhances tubular cell Ets-1 expression and associated down stream signaling is mediated through AT1 receptors.

  Renal failure 20100101

• Inhibitory effects of uraemic toxins 3-indoxyl sulfate and p-cresol on losartan metabolism in vitro.

  The Journal of pharmacy and pharmacology 20100101

• Do we need more than just powerful blood pressure reductions? New paradigms in end-organ protection.

  Vascular health and risk management 20100101

• Blocking the RAAS at different levels: an update on the use of the direct renin inhibitors alone and in combination.

  Vascular health and risk management 20100101

• Blood pressure-independent effect of candesartan on cardio-ankle vascular index in hypertensive patients with metabolic syndrome.

  Vascular health and risk management 20100101

• Concentration-dependent inhibitory effect of irbesartan on renal uric acid transporters.

  Journal of pharmacological sciences 20100101

• Preventive effect of taurine on experimental type II diabetic nephropathy.

  Journal of biomedical science 20100101

• Different effects of angiotensin II and angiotensin-(1-7) on vascular smooth muscle cell proliferation and migration.

  PloS one 20100101

• Pleural effusions in children undergoing cardiac surgery.

  Annals of pediatric cardiology 20100101

• Palmaria palmata (Dulse) as an unusual maritime aetiology of hyperkalemia in a patient with chronic renal failure: a case report.

  Journal of medical case reports 20100101

• AT1 receptor induced alterations in histone H2A reveal novel insights into GPCR control of chromatin remodeling.

  PloS one 20100101

• Optimal management of sarcopenia.

  Clinical interventions in aging 20100101

• Role of olmesartan in combination therapy in blood pressure control and vascular function.

  Vascular health and risk management 20100101

• Aliskiren and valsartan combination therapy for the management of hypertension.

  Vascular health and risk management 20100101

• Recent advances in the management of chronic stable angina II. Anti-ischemic therapy, options for refractory angina, risk factor reduction, and revascularization.

  Vascular health and risk management 20100101

• Triple combination therapy with amlodipine, valsartan, and hydrochlorothiazide vs dual combination therapy with amlodipine and hydrochlorothiazide for stage 2 hypertensive patients.

  Vascular health and risk management 20100101

• Electrocardiographic changes with the onset of diabetes and the impact of aerobic exercise training in the Zucker Diabetic Fatty (ZDF) rat.

  Cardiovascular diabetology 20100101

• Digital ischemia in scleroderma spectrum of diseases.

  International journal of rheumatology 20100101

• Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathy.

  Journal of translational medicine 20100101

• Renal protection in diabetes: lessons from ONTARGET.

  Cardiovascular diabetology 20100101

• Inflammation and adipose tissue: effects of progressive load training in rats.

  Lipids in health and disease 20100101

• Ventricular septal defect in a child with Alport syndrome: a case report.

  BMC cardiovascular disorders 20100101

• Methods for imaging Renin-synthesizing, -storing, and -secreting cells.

  International journal of hypertension 20100101

• Cardiovascular Disease, Single Nucleotide Polymorphisms; and the Renin Angiotensin System: Is There a MicroRNA Connection?

  International journal of hypertension 20100101

• PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice.

  Cardiovascular diabetology 20100101

• New class of agents for treatment of hypertension: focus on direct renin inhibition.

  Vascular health and risk management 20100101

• Urinary proteome analysis enables assessment of renoprotective treatment in type 2 diabetic patients with microalbuminuria.

  BMC nephrology 20100101

• Outcome selection and role of patient reported outcomes in contemporary cardiovascular trials: systematic review.

  BMJ (Clinical research ed.) 20100101

• Association between different measurements of blood pressure variability by ABP monitoring and ankle-brachial index.

  BMC cardiovascular disorders 20100101

• Diabetic cardiomyopathy: from the pathophysiology of the cardiac myocytes to current diagnosis and management strategies.

  Vascular health and risk management 20100101

• Population based screening for chronic kidney disease: cost effectiveness study.

  BMJ (Clinical research ed.) 20100101

• SNP-SNP interactions dominate the genetic architecture of candidate genes associated with left ventricular mass in African-Americans of the GENOA study.

  BMC medical genetics 20100101

• Reference left atrial dimensions and volumes by steady state free precession cardiovascular magnetic resonance.

  Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20100101

• Methylglyoxal augments angiotensin II-induced contraction in rat isolated carotid artery.

  Journal of pharmacological sciences 20100101

• [Effects of combination therapy with losartan/hydrochlorothiazide on the relationships between base blood pressure, autonomic function, and health-related QOL].

  Nihon Jinzo Gakkai shi 20100101

• Angiotensin-converting enzyme inhibitors will help in improving stroke outcome if given immediately after stroke.

  Annals of Indian Academy of Neurology 20100101

• Effects of atorvastatin and losartan on monocrotaline-induced pulmonary artery remodeling in rats.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20100101

• [An experience of the use of angiotensin II receptor blocker losartan in patients with metabolic syndrome and chronic kidney disease].

  Kardiologiia 20100101

• Effects of aliskiren on stroke in rats expressing human renin and angiotensinogen genes.

  PloS one 20100101

• Fibrillin assemblies: extracellular determinants of tissue formation and fibrosis.

  Fibrogenesis & tissue repair 20100101

• Single-dose effects of isosorbide mononitrate alone or in combination with losartan on central blood pressure.

  Journal of the American Society of Hypertension : JASH 20100101

• Efficacy of combination therapy with telmisartan plus amlodipine in patients with poorly controlled hypertension.

  Oxidative medicine and cellular longevity 20100101

• Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1.

  PloS one 20100101

• Clinical effectiveness of telmisartan alone or in combination therapy for controlling blood pressure and vascular risk in the elderly.

  Clinical interventions in aging 20100101

• Plasmapheresis-induced clinical improvement in a patient with steroid-resistant nephrotic syndrome due to podocin (NPHS2) gene mutation.

  Acta medica (Hradec Kralove) 20100101

• Prevention of sodium valproate-induced hepatotoxicity by curcumin, rosiglitazone and N-acetylcysteine in rats.

  Arzneimittel-Forschung 20100101

• Food and drug administration's critical path initiative and innovations in drug development paradigm: Challenges, progress, and controversies.

  Journal of pharmacy & bioallied sciences 20100101

• Spectrophotometric method for simultaneous estimation of atenolol in combination with losartan potassium and hydrochlorothiazide in bulk and tablet formulation.

  Journal of pharmacy & bioallied sciences 20100101

• Cardio classics revisited--focus on the role of candesartan.

  Vascular health and risk management 20100101

• Epidemiology of gout.

  Arthritis research & therapy 20100101

• Organic nitrates and nitrate resistance in diabetes: the role of vascular dysfunction and oxidative stress with emphasis on antioxidant properties of pentaerithrityl tetranitrate.

  Experimental diabetes research 20100101

• Predictors of uncontrolled hypertension and antihypertensive medication nonadherence.

  Journal of cardiovascular disease research 20100101

• Dexamethasone pulse therapy in patients of systemic sclerosis: is it a viable proposition? A study from kashmir.

  Indian journal of dermatology 20100101

• Achievement of cardiovascular risk factor targets in young adults with diabetes mellitus.

  Diabetes, metabolic syndrome and obesity : targets and therapy 20100101

• [Individual renal hemodynamic response to chronic angiotensin II receptor blockade and the influence on the renin-angiotensin system gene polymorphisms].

  Medicinski pregled 20100101

• Role of the JAK2/STAT pathway and losartan in human glomerular mesangial cell senescence.

  Molecular medicine reports 20100101

• Renovascular and renoprotective properties of telmisartan: clinical utility.

  International journal of nephrology and renovascular disease 20100101

• Uncontrolled hypertension secondary to leukemic cell infiltration of kidneys in a hemodialysis patient.

  International journal of nephrology and renovascular disease 20100101

• Fifteen years of losartan: what have we learned about losartan that can benefit chronic kidney disease patients?

  International journal of nephrology and renovascular disease 20100101

• New and improved strategies for the treatment of gout.

  International journal of nephrology and renovascular disease 20100101

• Antihypertensive drugs and erectile dysfunction as seen in spontaneous reports, with focus on angiotensin II type 1 receptor blockers.

  Drug, healthcare and patient safety 20100101

• Management of amlodipine-induced gingival enlargement: Series of three cases.

  Journal of Indian Society of Periodontology 20100101

• Policies to enhance prescribing efficiency in europe: findings and future implications.

  Frontiers in pharmacology 20100101

• Complementary mechanisms of action and rationale for the fixed combination of perindopril and indapamide in treating hypertension - update on clinical utility.

  Integrated blood pressure control 20100101

• Endothelial function, blood pressure control, and risk modification: impact of irbesartan alone or in combination.

  Integrated blood pressure control 20100101

• Evidence-based approach for managing hypertension in type 2 diabetes.

  Integrated blood pressure control 20100101

• Update on the role of candesartan in the optimal management of hypertension and cardiovascular risk reduction.

  Integrated blood pressure control 20100101

• Critical appraisal and pooled analysis of telmisartan alone or in combination with hydrochlorothiazide for achieving blood pressure goals.

  Integrated blood pressure control 20100101

• Impact of telmisartan in modifying vascular risk.

  Integrated blood pressure control 20100101

• Critical appraisal of amlodipine and olmesartan medoxomil fixed-dose combination in achieving blood pressure goals.

  Integrated blood pressure control 20100101

• Impact of olmesartan on blood pressure, endothelial function, and cardiovascular outcomes.

  Integrated blood pressure control 20100101

• Renoprotection, renin inhibition, and blood pressure control: the impact of aliskiren on integrated blood pressure control.

  Integrated blood pressure control 20100101

• Safety and tolerability of fixed antihypertensive combinations in blood pressure control: focus on olmesartan medoxomil and amlodipine combination.

  Integrated blood pressure control 20100101

• First-line treatment of hypertension: critical appraisal of potential role of aliskiren and hydrochlorothiazide in a fixed combination.

  Integrated blood pressure control 20100101

• A method for content uniformity determination of atenolol and losartan potassium in combined tablet dosage form.

  Indian journal of pharmaceutical sciences 20100101

• Wenckebach Block due to Hyperkalemia: A Case Report.

  Emergency medicine international 20100101

• Alzheimer's and seizures: interleukin-18, indoleamine 2,3-dioxygenase and quinolinic Acid.

  International journal of tryptophan research : IJTR 20100101

• Inflammatory cytokines and atrial fibrillation: current and prospective views.

  Journal of inflammation research 20100101

• Trouble shooting during bioanalytical estimation of drug and metabolites using lc-ms/ms: a review.

  Journal of advanced pharmaceutical technology & research 20100101

• A novel method for quantitative determination of aceclofenac in bulk drug and tablets using sodium salicylate as a hydrotropic solubilizing agent.

  Journal of advanced pharmaceutical technology & research 20100101

• Development of matrix type transdermal patches of lercanidipine hydrochloride: physicochemical and in-vitro characterization.

  Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101

• Angiotensin III modulates the nociceptive control mediated by the periaqueductal gray matter.

  Neuroscience 20091215

• The cardiovascular response of normal rats to dual lesion of the subfornical organ and area postrema at rest and to chronic losartan.

  Brain research 20091211

• Endothelial function impairment in chronic venous insufficiency: effect of some cardiovascular protectant agents.

  Angiology 20091201

• Effects of apocynin and losartan treatment on renal oxidative stress in a rat model of calcium oxalate nephrolithiasis.

  International urology and nephrology 20091201

• Prenatal blockade of Ang II receptors affects neonatal rat hindbrain structure and receptor localization.

  Experimental neurology 20091201

• QRS duration predicts sudden cardiac death in hypertensive patients undergoing intensive medical therapy: the LIFE study.

  European heart journal 20091201

• Evaluation of the potential for drug-induced liver injury based on in vitro covalent binding to human liver proteins.

  Drug metabolism and disposition: the biological fate of chemicals 20091201

• Impact of the PPAR-gamma2 Pro12Ala polymorphism and ACE inhibitor therapy on new-onset microalbuminuria in type 2 diabetes: evidence from BENEDICT.

  Diabetes 20091201

• Rosuvastatin attenuates Ang II--mediated cardiomyocyte hypertrophy via inhibition of LOX-1.

  Journal of cardiovascular pharmacology and therapeutics 20091201

• Safety and benefits of a tablet combining losartan and hydrochlorothiazide in Japanese diabetic patients with hypertension.

  Hypertension research : official journal of the Japanese Society of Hypertension 20091201

• Angiotensin II and hypertonicity modulate proximal tubular aquaporin 1 expression.

  American journal of physiology. Renal physiology 20091201

• Effect of treatment with losartan on salt sensitivity and SGLT2 expression in hypertensive diabetic rats.

  Diabetes research and clinical practice 20091201

• Effects of losartan, HO-1 inducers or HO-1 inhibitors on erectile signaling in diabetic rats.

  The journal of sexual medicine 20091201

• Angiotensin II regulates the expression of monocyte chemoattractant protein-1 in pancreatic cancer cells.

  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20091201

• Direct renin inhibition: an update.

  Current hypertension reports 20091201

• Permeation of losartan across human respiratory epithelium: an in vitro study with Calu-3 cells.

  Acta pharmaceutica (Zagreb, Croatia) 20091201

• Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy.

  Journal of the American Society of Nephrology : JASN 20091201

• Renin-Angiotensin system suppression mitigates experimental radiation pneumonitis.

  International journal of radiation oncology, biology, physics 20091201

• AGTR1 as a therapeutic target in ER-positive and ERBB2-negative breast cancer cases.

  Cell cycle (Georgetown, Tex.) 20091201

• Hemodynamic alterations in the coronary circulation of cardiomyopathic hamsters: age and Ang II-dependent mechanisms.

  Journal of cardiac failure 20091201

• Symptomatic hypocalcemia in primary hyperaldosteronism: a case report.

  Journal of Korean medical science 20091201

• Early administration of enalapril and losartan to patients with type 1 diabetes.

  Current diabetes reports 20091201

• Contribution of epidermal growth factor receptor transactivation in angiotensin II-induced enhanced expression of Gi protein and proliferation in A10 vascular smooth muscle cells.

  Canadian journal of physiology and pharmacology 20091201

• Biochemical effects of irbesartan in experimental diabetic nephropathy.

  Indian journal of pharmacology 20091201

• Divergent effects of losartan and metoprolol on cardiac remodeling, c-kit+ cells, proliferation and apoptosis in the left ventricle after myocardial infarction.

  Clinical and translational science 20091201

• Experimental therapies in hypertrophic cardiomyopathy.

  Journal of cardiovascular translational research 20091201

• Water and sodium regulation in heart failure.

  Electrolyte & blood pressure : E & BP 20091201

• Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (HEAAL study): a randomised, double-blind trial.

  Lancet (London, England) 20091128

• Optimising management of chronic heart failure.

  Lancet (London, England) 20091128

• Losartan-antioxidant hybrids: novel molecules for the prevention of hypertension-induced cardiovascular damage.

  Journal of medicinal chemistry 20091126

• Multivariate optimization and validation of an analytical methodology by RP-HPLC for the determination of losartan potassium in capsules.

  Talanta 20091115

• Influence of endogenous angiotensin II on control of sympathetic nerve activity in human dehydration.

  The Journal of physiology 20091115

• Urinary TGF-beta1 as an indicator of antiproteinuric response to angiotensin II receptor blocker in proteinuric renal diseases.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20091101

• Clustered metabolic abnormalities blunt regression of hypertensive left ventricular hypertrophy: the LIFE study.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20091101

• Angiotensin II activates connective tissue growth factor and induces extracellular matrix changes involving Smad/activation and p38 mitogen-activated protein kinase signalling pathways in human dermal fibroblasts.

  Experimental dermatology 20091101

• Effect of losartan on ambulatory short-term blood pressure variability and cardiovascular remodeling in hypertensive patients on hemodialysis.

  Atherosclerosis 20091101

• Angiotensin type 1 receptor mediates thyroid hormone-induced cardiomyocyte hypertrophy through the Akt/GSK-3beta/mTOR signaling pathway.

  Basic research in cardiology 20091101

• V1/V2 Vasopressin receptor antagonism potentiates the renoprotection of renin-angiotensin system inhibition in rats with renal mass reduction.

  Kidney international 20091101

• Enhanced angiotensin-mediated excitation of renal sympathetic nerve activity within the paraventricular nucleus of anesthetized rats with heart failure.

  American journal of physiology. Regulatory, integrative and comparative physiology 20091101

• Effects of angiotensin II type 1 receptor blocker on ambulatory blood pressure variability in hypertensive patients with overt diabetic nephropathy.

  Hypertension research : official journal of the Japanese Society of Hypertension 20091101

• Regulation of central angiotensin type 1 receptors and sympathetic outflow in heart failure.

  American journal of physiology. Heart and circulatory physiology 20091101

• AT1 receptor-mediated uptake of angiotensin II and NHE-3 expression in proximal tubule cells through a microtubule-dependent endocytic pathway.

  American journal of physiology. Renal physiology 20091101

• Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism.

  American journal of physiology. Heart and circulatory physiology 20091101

• Vasopressin is a major vasoconstrictor involved in hindlimb vascular responses to stimulation of adenosine A(1) receptors in the nucleus of the solitary tract.

  American journal of physiology. Heart and circulatory physiology 20091101

• Ischemia-induced brain damage is enhanced in human renin and angiotensinogen double-transgenic mice.

  American journal of physiology. Regulatory, integrative and comparative physiology 20091101

• Angiotensin II receptors are expressed and functional in human esophageal mucosa.

  American journal of physiology. Gastrointestinal and liver physiology 20091101

• Angiotensin II effects on ischemic focal ventricular tachycardia are predominantly mediated through myocardial AT(2) receptor.

  American journal of physiology. Heart and circulatory physiology 20091101

• Long-term effects of losartan on structure and function of the thoracic aorta in a mouse model of Marfan syndrome.

  British journal of pharmacology 20091101

• Incidence of heart failure in relation to QRS duration during antihypertensive therapy: the LIFE study.

  Journal of hypertension 20091101

• Treatment of prehypertension in diabetes and metabolic syndrome: what are the pros?

  Diabetes care 20091101

• Hypertension and diabetes: should we treat early surrogates? What are the cons?

  Diabetes care 20091101

• Hypertension and Diabetes: what are the pros to treating early surrogates?

  Diabetes care 20091101

• Dual blockade of the renin-angiotensin system in diabetic nephropathy.

  Diabetes care 20091101

• Constitutively active mutant N111G of angiotensin II type 1 (AT(1)) receptor induces homologous internalization through mediation of AT(1)-receptor antagonist.

  Journal of pharmacological sciences 20091101

• Efficacy and safety of losartan in treatment of hyperuricemia and posttransplantation erythrocytosis: results of a prospective, open, randomized, case-control study.

  Transplantation proceedings 20091101

• Effects of angiotensin II receptor blockers on the relationships between ambulatory blood pressure and anti-hypertensive effects, autonomic function, and health-related quality of life.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20091101

• Outcome of heart failure with preserved ejection fraction: a multicentre spanish registry.

  Current cardiology reviews 20091101

• Hypertrophic response to angiotensin II is mediated by protein kinase D-extracellular signal-regulated kinase 5 pathway in human aortic smooth muscle cells.

  Biochemical and biophysical research communications 20091023

• Mitral E wave deceleration time to peak E velocity ratio and cardiovascular outcome in hypertensive patients during antihypertensive treatment (from the LIFE echo-substudy).

  The American journal of cardiology 20091015

• Treatment of hypertension in children and adolescents.

  Pediatric nephrology (Berlin, Germany) 20091001

• Effects of Angelicae tenuissima radix, Angelicae dahuricae radix and Scutellariae radix extracts on cytochrome P450 activities in healthy volunteers.

  Basic & clinical pharmacology & toxicology 20091001

• Changes seen in the aging kidney and the effect of blocking the renin-angiotensin system.

  Therapeutic advances in cardiovascular disease 20091001

• Angiotensin-(1-7) antagonist, A-779, microinjection into the caudal ventrolateral medulla of renovascular hypertensive rats restores baroreflex bradycardia.

  Peptides 20091001

• Brain AT1 angiotensin receptor subtype binding: importance of peptidase inhibition for identification of angiotensin II as its endogenous ligand.

  The Journal of pharmacology and experimental therapeutics 20091001

• Renal effects of aliskiren compared with and in combination with irbesartan in patients with type 2 diabetes, hypertension, and albuminuria.

  Diabetes care 20091001

• CYP2C9 genotype modifies activity of the renin-angiotensin-aldosterone system in hypertensive men.

  Journal of hypertension 20091001

• Effects of the CYP2C9*13 allele on the pharmacokinetics of losartan in healthy male subjects.

  Xenobiotica; the fate of foreign compounds in biological systems 20091001

• Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis C.

  American journal of physiology. Gastrointestinal and liver physiology 20091001

• Central angiotensin AT1 receptors are involved in metabolic adjustments in response to graded exercise in rats.

  Peptides 20091001

• Long-term effect of modification of dietary protein intake on the progression of diabetic nephropathy: a randomised controlled trial.

  Diabetologia 20091001

• Multivalent ligand-receptor interactions elicit inverse agonist activity of AT(1) receptor blockers against stretch-induced AT(1) receptor activation.

  Hypertension research : official journal of the Japanese Society of Hypertension 20091001

• Phosphate-activated glutaminase-containing neurons in the rat paraventricular nucleus express angiotensin type 1 receptors.

  Hypertension (Dallas, Tex. : 1979) 20091001

• Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3.

  Hypertension (Dallas, Tex. : 1979) 20091001

• Losartan metabolite EXP3179: an AT1-receptor-independent treatment strategy for patients with the metabolic syndrome?

  Hypertension (Dallas, Tex. : 1979) 20091001

• Protein kinase C-inhibiting properties of the losartan metabolite EXP3179 make the difference.

  Hypertension (Dallas, Tex. : 1979) 20091001

• Chronic treatment with losartan results in sufficient serum levels of the metabolite EXP3179 for PPARgamma activation.

  Hypertension (Dallas, Tex. : 1979) 20091001

• Losartan metabolite EXP3179 blocks NADPH oxidase-mediated superoxide production by inhibiting protein kinase C: potential clinical implications in hypertension.

  Hypertension (Dallas, Tex. : 1979) 20091001

• Lowering arterial pressure delays the oxidative stress generation in a renal experimental model of hypertension.

  Journal of cardiovascular pharmacology 20091001

• Production and secretion of adiponectin from 3T3-L1 adipocytes: comparison of antihypertensive drugs.

  American journal of hypertension 20091001

• Interaction between renin-angiotensin and sympathetic nervous systems in a rat model of pressure overload cardiac hypertrophy.

  Autonomic & autacoid pharmacology 20091001

• Rapid determination of losartan and losartan acid in human plasma by multiplexed LC-MS/MS.

  Journal of separation science 20091001

• Clinical experience in treating hypertension with fixed-dose combination therapy: angiotensin II receptor blocker losartan plus hydrochlorothiazide.

  Expert opinion on drug metabolism & toxicology 20091001

• Cost-effectiveness of aliskiren in type 2 diabetes, hypertension, and albuminuria.

  Journal of the American Society of Nephrology : JASN 20091001

• A randomized, double-blind, placebo-controlled study to determine the effects of valsartan on exercise time in patients with symptomatic heart failure with preserved ejection fraction.

  European journal of heart failure 20091001

• Renal and retinal effects of enalapril and losartan in type 1 diabetes.

  The New England journal of medicine 20091001

• Renal and retinal effects of enalapril and losartan in type 1 diabetes.

  The New England journal of medicine 20091001

• Safety and feasibility of achieving lower systolic blood pressure goals in persons with type 2 diabetes: the SANDS trial.

  Journal of clinical hypertension (Greenwich, Conn.) 20091001

• Chronic treatment with losartan (angiotensin II type 1 receptor antagonist) normalizes enhanced acetylcholine-induced coronary vasoconstriction in isolated perfused hearts of type 2 diabetic OLETF rats.

  Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20091001

• Loeys-Dietz syndrome: a Marfan-like syndrome associated with aggressive vasculopathy.

  Singapore medical journal 20091001

• [Effects of losartan and simvastatin on collagen content, myocardial expression of MMP-2 mRNA, MMP-9 mRNA and TIMP-1 mRNA, TIMP-2 mRNA in pressure overload rat hearts].

  Zhonghua xin xue guan bing za zhi 20091001

• Angiotensin converting enzyme gene polymorphism in type II diabetics with nephropathy.

  Indian journal of nephrology 20091001

• Neointimal-specific induction of apoptosis by losartan results in regression of vascular lesion in rat aorta.

  European journal of pharmacology 20090915

• High ambient glucose induces angiotensin-independent AT-1 receptor activation, leading to increases in proliferation and extracellular matrix accumulation in MES-13 mesangial cells.

  The Biochemical journal 20090914

• Determination of losartan, telmisartan, and valsartan by direct injection of human urine into a column-switching liquid chromatographic system with fluorescence detection.

  Journal of pharmaceutical and biomedical analysis 20090908

• Losartan reduces liver expression of plasminogen activator inhibitor-1 (PAI-1) in a high fat-induced rat nonalcoholic fatty liver disease model.

  Atherosclerosis 20090901

• Prevention of aortic elastic lamina defects by losartan in apolipoprotein(E)-deficient mouse.

  Clinical and experimental pharmacology & physiology 20090901

• Long-term regulation of vacuolar H(+)-ATPase by angiotensin II in proximal tubule cells.

  Pflugers Archiv : European journal of physiology 20090901

• Losartan and tempol treatments normalize the increased response to hydrogen peroxide in resistance arteries from hypertensive rats.

  Journal of hypertension 20090901

• In vitro and in vivo studies on chitosan beads of losartan Duolite AP143 complex, optimized by using statistical experimental design.

  AAPS PharmSciTech 20090901

• Angiotensin II up-regulates PAX2 oncogene expression and activity in prostate cancer via the angiotensin II type I receptor.

  The Prostate 20090901

• The uterine placental bed Renin-Angiotensin system in normal and preeclamptic pregnancy.

  Endocrinology 20090901

• Diabetes mellitus and expression of the enterocyte renin-angiotensin system: implications for control of glucose transport across the brush border membrane.

  American journal of physiology. Cell physiology 20090901

• Long-term therapeutic effect of vitamin D analog doxercalciferol on diabetic nephropathy: strong synergism with AT1 receptor antagonist.

  American journal of physiology. Renal physiology 20090901

• Immunosuppressive effect of angiotensin receptor blocker on stimulation of mice CTLs by angiotensin II.

  International immunopharmacology 20090901

• Substrate-dependent functional alterations of seven CYP2C9 variants found in Japanese subjects.

  Drug metabolism and disposition: the biological fate of chemicals 20090901

• Regulation of glucose uptake in mesangial cells stimulated by high glucose: role of angiotensin II and insulin.

  Experimental biology and medicine (Maywood, N.J.) 20090901

• Sympathetic-mediated hypertension of awake juvenile rats submitted to chronic intermittent hypoxia is not linked to baroreflex dysfunction.

  Experimental physiology 20090901

• Is there a role for direct renin inhibitors in chronic kidney disease?

  Current opinion in nephrology and hypertension 20090901

• Endogenous angiotensin II facilitates GABAergic neurotransmission afferent to the Na+-responsive neurons of the rat median preoptic nucleus.

  American journal of physiology. Regulatory, integrative and comparative physiology 20090901

• Mouse GLUT9: evidences for a urate uniporter.

  American journal of physiology. Renal physiology 20090901

• Chronic central versus systemic blockade of AT(1) receptors and cardiac dysfunction in rats post-myocardial infarction.

  American journal of physiology. Heart and circulatory physiology 20090901

• Losartan reduces the onset of type 2 diabetes in hypertensive Japanese patients with chronic hepatitis C.

  Journal of medical virology 20090901

• Chlorthalidone - a renaissance in use?

  Expert opinion on pharmacotherapy 20090901

• AT(1) receptor blockers increase insulin-like growth factor-I production by stimulating sensory neurons in spontaneously hypertensive rats.

  Translational research : the journal of laboratory and clinical medicine 20090901

• Renal dysfunction potentiates foam cell formation by repressing ABCA1.

  Arteriosclerosis, thrombosis, and vascular biology 20090901

• CYP2C9 genotype and pharmacodynamic responses to losartan in patients with primary and secondary kidney diseases.

  European journal of clinical pharmacology 20090901

• Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster.

  The Journal of clinical investigation 20090901

• Antiproteinuric and blood pressure-lowering effects of a fixed-dose combination of losartan and hydrochlorothiazide in hypertensive patients with stage 3 chronic kidney disease.

  Pharmacotherapy 20090901

• Fluorofenidone attenuates collagen I and transforming growth factor-beta1 expression through a nicotinamide adenine dinucleotide phosphate oxidase-dependent way in NRK-52E cells.

  Nephrology (Carlton, Vic.) 20090901

• Long-term effects of rosiglitazone on the progressive decline in renal function in patients with type 2 diabetes.

  The Korean journal of internal medicine 20090901

• Effect of angiotensin II type-1 receptor blockers on stable allograft kidneys: prospective randomized study.

  Transplantation proceedings 20090901

• Additive antihypertensive and antihypertrophic effects of long-acting Ca blockers in uncontrolled hypertensive patients with angiotensin-receptor blocker based treatment.

  International heart journal 20090901

• Genetic polymorphism of the human cytochrome P450 2C9 gene and its clinical significance.

  Current drug metabolism 20090901

• Clinical trials of the past decade in the management of chronic kidney disease.

  Reviews on recent clinical trials 20090901

• Correction of endothelial dysfunction with impaza preparation in complex with enalapril and losartan during modeling of NO deficiency.

  Bulletin of experimental biology and medicine 20090901

• Effect of impaza on cardiovascular system.

  Bulletin of experimental biology and medicine 20090901

• Experimental study of hypotensive effect of kardos in rats with inherited hypertension.

  Bulletin of experimental biology and medicine 20090901

• Circulating transforming growth factor-beta in Marfan syndrome.

  Circulation 20090811

• Losartan exerts renoprotection through NAD(P)H oxidase downregulation in a renovascular model of hypertension.

  Regulatory peptides 20090807

• Effects of high sodium intake and diuretics on the circadian rhythm of blood pressure in type 2 diabetic patients treated with an angiotensin II receptor blocker.

  Clinical and experimental nephrology 20090801

• Crosstalk between peroxisome proliferator-activated receptor-gamma and angiotensin II in renal tubular epithelial cells in IgA nephropathy.

  Clinical immunology (Orlando, Fla.) 20090801

• Primary aldosteronism: diagnostic accuracy of the losartan and captopril tests.

  American journal of hypertension 20090801

• PPARgamma agonist, rosiglitazone, regulates angiotensin II-induced vascular inflammation through the TLR4-dependent signaling pathway.

  Laboratory investigation; a journal of technical methods and pathology 20090801

• Catheter ablation vs. amiodarone plus losartan for prevention of atrial fibrillation recurrence in patients with paroxysmal atrial fibrillation.

  European journal of clinical investigation 20090801

• Genetic variant of the Renin-Angiotensin system and diabetes influences blood pressure response to Angiotensin receptor blockers.

  Diabetes care 20090801

• Antagonist of the type-1 ANG II receptor prevents against LPS-induced septic shock in rats.

  Intensive care medicine 20090801

• Dual ACE-inhibition and AT1 receptor antagonism improves ventricular lusitropy without affecting cardiac fibrosis in the congenic mRen2.Lewis rat.

  Therapeutic advances in cardiovascular disease 20090801

• Effects of salt supplementation on the albuminuric response to telmisartan with or without hydrochlorothiazide therapy in hypertensive patients with type 2 diabetes are modulated by habitual dietary salt intake.

  Diabetes care 20090801

• Synergistic inhibitory effect of gemcitabine and angiotensin type-1 receptor blocker, losartan, on murine pancreatic tumor growth via anti-angiogenic activities.

  Oncology reports 20090801

• Effect of adrenotensin on cell proliferation is mediated by angiotensin II in cultured rat mesangial cells.

  Acta pharmacologica Sinica 20090801

• The value of irbesartan in the management of hypertension.

  Expert opinion on pharmacotherapy 20090801

• Renoprotect and blood pressure lowering effect of low-dose hydrochlorothiazide added to intensive renin-angiotensin inhibition in hypertensive patients with chronic kidney disease.

  International journal of clinical pharmacology and therapeutics 20090801

• Effects of angiotensin receptor blocker on oxidative stress and cardio-renal function in streptozotocin-induced diabetic rats.

  Biological & pharmaceutical bulletin 20090801

• Left ventricular hypertrophy may be transient in the emergency department.

  The western journal of emergency medicine 20090801

• Effects of losartan on catecholamine release in the isolated rat adrenal gland.

  The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20090801

• Effect of enalapril and losartan on proteinuria in type 2 diabetic nephropathy patients.

  Bangladesh Medical Research Council bulletin 20090801

• Diminished renal function and the incidence of heart failure.

  Current cardiology reviews 20090801

• Binding sites of valsartan, candesartan and losartan with angiotensin II receptor 1 subtype by molecular modeling.

  Life sciences 20090717

• Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan.

  Journal of immunology (Baltimore, Md. : 1950) 20090715

• Renal and retinal effects of enalapril and losartan in type 1 diabetes.

  The New England journal of medicine 20090702

• The angiotensin-calcineurin-NFAT pathway mediates stretch-induced up-regulation of matrix metalloproteinases-2/-9 in atrial myocytes.

  Basic research in cardiology 20090701

• Consequences of perinatal treatment with L-arginine and antioxidants for the renal transcriptome in spontaneously hypertensive rats.

  Pflugers Archiv : European journal of physiology 20090701

• Effects of combination therapy with perindopril and losartan on left ventricular remodelling in patients with myocardial infarction.

  Clinical and experimental pharmacology & physiology 20090701

• Fabry disease: progression of nephropathy, and prevalence of cardiac and cerebrovascular events before enzyme replacement therapy.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090701

• The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice.

  Journal of lipid research 20090701

• Prevalence of microalbuminuria and associated electrocardiographic abnormalities in an Indo-Asian population.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090701

• Endogenous angiotensin II has fewer effects but neuronal nitric oxide synthase has excitatory effects on renal sympathetic nerve activity in salt-sensitive hypertension-induced heart failure.

  The journal of physiological sciences : JPS 20090701

• Enhanced cardiac sympathetic afferent reflex involved in sympathetic overactivity in renovascular hypertensive rats.

  Experimental physiology 20090701

• AT(1) receptor activation regulates the mRNA expression of CAT1, CAT2, arginase-1, and DDAH2 in preglomerular vessels from angiotensin II hypertensive rats.

  American journal of physiology. Renal physiology 20090701

• (Pro)renin receptor-mediated signal transduction and tissue renin-angiotensin system contribute to diabetes-induced retinal inflammation.

  Diabetes 20090701

• Effect of early versus late AT(1) receptor blockade with losartan on postmyocardial infarction ventricular remodeling in rabbits.

  American journal of physiology. Heart and circulatory physiology 20090701

• Angiotensin II receptor blockers in pregnancy: a report of five cases.

  Reproductive toxicology (Elmsford, N.Y.) 20090701

• A randomized, comparative study evaluating the efficacy and tolerability of losartan-low dose chlorthalidone (6.25 mg) combination with losartan-hydrochlorothiazide (12.5 mg) combination in Indian patients with mild-to-moderate essential hypertension.

  Expert opinion on pharmacotherapy 20090701

• Proniosomal transdermal therapeutic system of losartan potassium: development and pharmacokinetic evaluation.

  Journal of drug targeting 20090701

• Hydrophilic interaction chromatography-tandem mass spectrometric analysis of irbesartan in human plasma: application to pharmacokinetic study of irbesartan.

  Journal of separation science 20090701

• (Pro)renin receptor: a treatment target for diabetic retinopathy?

  Diabetes 20090701

• Anemia, diabetes, and chronic kidney disease.

  Diabetes care 20090701

• Endogenous angiotensin II modulates nNOS expression in renovascular hypertension.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20090701

• [Combination therapy of ARB with diuretics in Japanese hypertensive patients].

  Nihon rinsho. Japanese journal of clinical medicine 20090701

• Health-related quality of life and blood pressure control in hypertensive patients with and without complications.

  Clinics (Sao Paulo, Brazil) 20090701

• Comparative evaluation of the antihypertensive activities of losartan and HM70186 during liver dysfunction.

  Archives of pharmacal research 20090701

• Comparative antihypertensive activities of losartan and HM70186 in rats with hepatic dysfunction.

  Archives of pharmacal research 20090701

• [NADPH oxidase-derived reactive oxygen species involved in angiotensin II-induced monocyte chemoattractant protein-1 expression in mesangial cells].

  Zhonghua bing li xue za zhi = Chinese journal of pathology 20090701

• Simultaneous determination of losartan and hydrochlorothiazide in human plasma by LC/MS/MS with electrospray ionization and its application to pharmacokinetics.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20090701

• Coronary artery disease, left ventricular hypertrophy and diastolic dysfunction are associated with stroke in patients affected by persistent non-valvular atrial fibrillation: a case-control study.

  Heart international 20090630

• The angiotensin II-AT1 receptor stimulates reactive oxygen species within the cell nucleus.

  Biochemical and biophysical research communications 20090626

• Losartan/Hydrochlorothiazide: a review of its use in the treatment of hypertension and for stroke risk reduction in patients with hypertension and left ventricular hypertrophy.

  Drugs 20090618

• [Hypertension and the heart].

  Ugeskrift for laeger 20090615

• Chronic treatment with losartan and carvedilol differentially modulates renal vascular responses to sympathomimetics compared to treatment with individual agents in normal Wistar Kyoto and spontaneously hypertensive rats.

  European journal of pharmacology 20090610

• Prolonged exposure of cardiac cells to renin plus angiotensinogen reduces intracellular renin in the failing heart. On the role of angiotensin II-AT1 complex internalization.

  Regulatory peptides 20090605

• Renal medullary effects of transient prehypertensive treatment in young spontaneously hypertensive rats.

  Acta physiologica (Oxford, England) 20090601

• Induction of apoptosis in leukemic cell lines treated with captopril, trandolapril and losartan: a new role in the treatment of leukaemia for these agents.

  Leukemia research 20090601

• Angiotensin-(1-7) activates a tyrosine phosphatase and inhibits glucose-induced signalling in proximal tubular cells.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090601

• Adiponectin is positively associated with insulin resistance in subjects with type 2 diabetic nephropathy and effects of angiotensin II type 1 receptor blocker losartan.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090601

• Cardiovascular and autonomic phenotype of db/db diabetic mice.

  Experimental physiology 20090601

• Effect of silymarin on the pharmacokinetics of losartan and its active metabolite E-3174 in healthy Chinese volunteers.

  European journal of clinical pharmacology 20090601

• Beneficial effect of triple treatment plus immunoglobulin in experimental nephrotic syndrome.

  Pediatric nephrology (Berlin, Germany) 20090601

• Nuclear angiotensin II type 2 (AT2) receptors are functionally linked to nitric oxide production.

  American journal of physiology. Renal physiology 20090601

• Brain nuclear factor-kappa B activation contributes to neurohumoral excitation in angiotensin II-induced hypertension.

  Cardiovascular research 20090601

• HPLC determination of irbesartan in human plasma: its application to pharmacokinetic studies.

  Biomedical chromatography : BMC 20090601

• Diabetic retinal neurodegeneration is associated with mitochondrial oxidative stress and is improved by an angiotensin receptor blocker in a model combining hypertension and diabetes.

  Diabetes 20090601

• Impact of diabetes on treatment-induced changes in left ventricular structure and function in hypertensive patients with left ventricular hypertrophy. The LIFE study.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20090601

• Time courses of subcellular signal transduction and cellular apoptosis in remote viable myocardium of rat left ventricles following acute myocardial infarction: role of pharmacomodulation.

  Journal of cardiovascular pharmacology and therapeutics 20090601

• Antihypertensive effects of central ablations in spontaneously hypertensive rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20090601

• Involvement of central angiotensin II type 1 receptors in LPS-induced systemic vasopressin release and blood pressure regulation in rats.

  Journal of applied physiology (Bethesda, Md. : 1985) 20090601

• Losartan preserves erectile function after bilateral cavernous nerve injury via antifibrotic mechanisms in male rats.

  The Journal of urology 20090601

• Effectiveness of open-label losartan/hydrochlorothiazide combination therapy in Asian patients with hypertension not controlled with ACE inhibitor or ARB monotherapy.

  Hypertension research : official journal of the Japanese Society of Hypertension 20090601

• Effect of soy extract administration on losartan pharmacokinetics in healthy female volunteers.

  The Annals of pharmacotherapy 20090601

• Effects of structured versus usual care on renal endpoint in type 2 diabetes: the SURE study: a randomized multicenter translational study.

  Diabetes care 20090601

• Intensive diabetes management for high-risk patients: how best to deliver?

  Diabetes care 20090601

• The effect of enalapril on skin flap viability is independent of angiotensin II AT1 receptors.

  Annals of plastic surgery 20090601

• Gout--what are the treatment options?

  Expert opinion on pharmacotherapy 20090601

• Late renal medullary effects of transient angiotensin II receptor blockade in immature spontaneously hypertensive rats.

  Acta physiologica (Oxford, England) 20090601

• Beneficial effects of high-dose losartan in IgA nephritis.

  Clinical nephrology 20090601

• [Losartan inhibits high glucose-induced CTGF expression via ERK1/2 MAPK pathways in mouse mesangial cells].

  Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20090601

• Established and newly proposed mechanisms of chronic cyclosporine nephropathy.

  The Korean journal of internal medicine 20090601

• Synergistic decrease in blood pressure by captopril combined with losartan in spontaneous hypertensive rats.

  Archives of pharmacal research 20090601

• Postural changes in blood pressure associated with interactions between candidate genes for chronic respiratory diseases and exposure to particulate matter.

  Environmental health perspectives 20090601

• IL-8/CXCL8 Upregulates 12-Lipoxygenase Expression in Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats.

  Immune network 20090601

• Mechanisms of potentiation of Angiotensin II-induced contractile response of isolated rat aorta by hydrogen peroxide and tert-butyryl hydroperoxide.

  Indian journal of pharmacology 20090601

• Rapid Hemodynamic Deterioration and Death due to Acute Severe Refractory Septic Shock.

  Journal of clinical medicine research 20090601

• Cuff-induced vascular intima thickening is influenced by titration of the Ace gene in mice.

  Physiological genomics 20090513

• Angiotensin II inhibits GABAergic synaptic transmission in dorsolateral periaqueductal gray neurons.

  Neuroscience letters 20090508

• Dihydrotestosterone stimulates aldosterone secretion by H295R human adrenocortical cells.

  Molecular and cellular endocrinology 20090506

• Losartan prevents sepsis-induced acute lung injury and decreases activation of nuclear factor kappaB and mitogen-activated protein kinases.

  Shock (Augusta, Ga.) 20090501

• Angiotensin II receptor 1 involved in the central pressor response induced by interleukin-1 beta in the paraventricular nucleus.

  Neurological research 20090501

• Extracellular matrix metalloproteinase inducer (EMMPRIN) is present in smooth muscle cells of human aneurysmal aorta and is induced by angiotensin II in vitro.

  Clinical science (London, England : 1979) 20090501

• Losartan inhibits monocytic adhesion induced by ADMA via downregulation of chemokine receptors in monocytes.

  European journal of clinical pharmacology 20090501

• Inhibition of angiotensin type 1 receptor impairs renal ability of K conservation in response to K restriction.

  American journal of physiology. Renal physiology 20090501

• Unexpected effect of angiotensin AT1 receptor blockade on tubuloglomerular feedback in early subtotal nephrectomy.

  American journal of physiology. Renal physiology 20090501

• Involvement of redox-sensitive extracellular-regulated kinases in angiotensin II-induced interleukin-6 expression in pancreatic acinar cells.

  The Journal of pharmacology and experimental therapeutics 20090501

• Angiotensin II upregulates hypothalamic AT1 receptor expression in rats via the mitogen-activated protein kinase pathway.

  American journal of physiology. Heart and circulatory physiology 20090501

• Defects in cutaneous angiotensin-converting enzyme 2 and angiotensin-(1-7) production in postural tachycardia syndrome.

  Hypertension (Dallas, Tex. : 1979) 20090501

• Transcriptome of hypertension-induced left ventricular hypertrophy and its regression by antihypertensive therapies.

  Hypertension research : official journal of the Japanese Society of Hypertension 20090501

• Diabetic cardiomyopathy.

  Clinical science (London, England : 1979) 20090501

• Erectile dysfunction and heart failure: the role of phosphodiesterase type 5 inhibitors.

  International journal of impotence research 20090501

• Effects of angiotensin II receptor blockers on relationships between 24-hour blood pressure, autonomic function, and health-related QOL.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20090501

• Valsartan vs. other angiotensin II receptor blockers in the treatment of hypertension: a meta-analytical approach.

  International journal of clinical practice 20090501

• Antiproteinuric therapy decreases LDL-cholesterol as well as HDL-cholesterol in non-diabetic proteinuric patients: relationships with cholesteryl ester transfer protein mass and adiponectin.

  Expert opinion on therapeutic targets 20090501

• Reduction of microalbuminuria by using losartan in normotensive patients with type 2 diabetes mellitus: A randomized controlled trial.

  Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20090501

• Astragalus mongholicus ameliorates renal fibrosis by modulating HGF and TGF-beta in rats with unilateral ureteral obstruction.

  Journal of Zhejiang University. Science. B 20090501

• Managing toxicities and optimal dosing of targeted drugs in advanced kidney cancer.

  Current oncology (Toronto, Ont.) 20090501

• CORD: COmparsion of Recommended Doses of ACE inhibitors and angiotensin II receptor blockers.

  Vnitrni lekarstvi 20090501

• Changes in the composition of the thoracic aortic wall in spontaneously hypertensive rats treated with losartan or spironolactone.

  Clinical and experimental pharmacology & physiology 20090501

• [Economic impact of Losartan use in type 2 diabetic patients with nephropathy].

  Revista medica de Chile 20090501

• The effect of telmisartan on endothelial function and arterial stiffness in patients with essential hypertension.

  Korean circulation journal 20090501

• Prognostic value of changes in the electrocardiographic strain pattern during antihypertensive treatment: the Losartan Intervention for End-Point Reduction in Hypertension Study (LIFE).

  Circulation 20090414

• Simultaneous quantification of losartan and active metabolite in human plasma by liquid chromatography-tandem mass spectrometry using irbesartan as internal standard.

  Journal of pharmaceutical and biomedical analysis 20090405

• Losartan decreased premature ventricular contractions in patients with hypertension.

  Journal of human hypertension 20090401

• Efficacy of exercise, losartan, enalapril, atenolol and rilmenidine in subjects with blood pressure hyperreactivity at treadmill stress test and left ventricular hypertrophy.

  Journal of human hypertension 20090401

• Reduced progression of adriamycin nephropathy in spontaneously hypertensive rats treated by losartan.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090401

• Prediction of the effects of genetic polymorphism on the pharmacokinetics of CYP2C9 substrates from in vitro data.

  Pharmaceutical research 20090401

• Nail-patella syndrome, infantile nephrotic syndrome: complete remission with antiproteinuric treatment.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090401

• Regulation of nerve growth factor in the heart: the role of the calcineurin-NFAT pathway.

  Journal of molecular and cellular cardiology 20090401

• Battle against the renin-angiotensin system: help from an unexpected party.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090401

• Chronic NHE-1 blockade induces an antiapoptotic effect in the hypertrophied heart.

  Journal of applied physiology (Bethesda, Md. : 1985) 20090401

• Antihypertensive therapy, new-onset diabetes, and cardiovascular disease.

  International journal of clinical practice 20090401

• Cerebral vasomotor reactivity before and after blood pressure reduction in hypertensive patients.

  American journal of hypertension 20090401

• Type-1 angiotensin receptors are expressed and transported in motor and sensory axons of rat sciatic nerves.

  Neuropeptides 20090401

• Short-term oral treatment with the angiotensin II receptor antagonist losartan does not improve coronary vasomotor function in asymptomatic type 2 diabetes patients.

  Diabetes research and clinical practice 20090401

• Efficacy and safety of losartan 100 mg or losartan 100 mg plus hydrochlorothiazide 25 mg in the treatment of patients with essential arterial hypertension and CV risk factors: observational, prospective study in primary care.

  Current medical research and opinion 20090401

• Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis.

  The Journal of clinical investigation 20090401

• Synergism of simvastatin with losartan prevents angiotensin II-induced cardiomyocyte apoptosis in vitro.

  The Journal of pharmacy and pharmacology 20090401

• A high-throughput assay using liquid chromatography-tandem mass spectrometry for simultaneous in vivo phenotyping of 5 major cytochrome p450 enzymes in patients.

  Therapeutic drug monitoring 20090401

• Protective effects of angiotensin AT1 receptor blockade in malignant hypertension in the rat.

  European journal of pharmacology 20090401

• [The contribution of ARB to medical treatment].

  Nihon rinsho. Japanese journal of clinical medicine 20090401

• [Pharmacological characteristics of ARB and potential strategy to develop novel ARB].

  Nihon rinsho. Japanese journal of clinical medicine 20090401

• Irbesartan and hydrochlorothiazide association in the treatment of hypertension.

  Current vascular pharmacology 20090401

• Exercise and cardiovascular outcomes in hypertensive patients in relation to structure and function of left ventricular hypertrophy: the LIFE study.

  European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20090401

• Ginsenoside Rb1, a panoxadiol saponin against oxidative damage and renal interstitial fibrosis in rats with unilateral ureteral obstruction.

  Chinese journal of integrative medicine 20090401

• [Effect of cordyceps sinensis extract on Klotho expression and apoptosis in renal tubular epithelial cells induced by angiotensin II].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20090401

• Rationale and design of a trial evaluating the effects of losartan vs. nebivolol vs. the association of both on the progression of aortic root dilation in Marfan syndrome with FBN1 gene mutations.

  Journal of cardiovascular medicine (Hagerstown, Md.) 20090401

• Endothelial and non-endothelial coronary blood flow reserve and left ventricular dysfunction in systemic hypertension.

  Clinics (Sao Paulo, Brazil) 20090401

• Association between inappropriateness of left ventricular mass and left ventricular diastolic dysfunction: a study using the tissue Doppler parameter, e/e'.

  Korean circulation journal 20090401

• Losartan/Hydrochlorothiazide fixed combination versus amlodipine monotherapy in korean patients with mild to moderate hypertension.

  Korean circulation journal 20090401

• Effect of lowering blood pressure on cardiovascular events and mortality in patients on dialysis: a systematic review and meta-analysis of randomised controlled trials.

  Lancet (London, England) 20090321

• Development of a CP 31P NMR broadline simulation methodology for studying the interactions of antihypertensive AT1 antagonist losartan with phospholipid bilayers.

  Biophysical journal 20090318

• Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway.

  Proceedings of the National Academy of Sciences of the United States of America 20090317

• Angiotensin II increases collagen I expression via transforming growth factor-beta1 and extracellular signal-regulated kinase in cardiac fibroblasts.

  European journal of pharmacology 20090315

• [Aliskiren combined with losartan in type 2-diabetes and nephropathy - secondary publication].

  Ugeskrift for laeger 20090309

• Effects of bradykinin on venous capacitance in health and treated chronic heart failure.

  Clinical science (London, England : 1979) 20090301

• Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats.

  Clinical and experimental pharmacology & physiology 20090301

• Angiotensin II reduces mitochondrial content in skeletal muscle and affects glycemic control.

  Diabetes 20090301

• Mechanisms in the PVN mediating local and central sodium-induced hypertension in Wistar rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20090301

• Increased vascular angiotensin type 2 receptor expression and NOS-mediated mechanisms of vascular relaxation in pregnant rats.

  American journal of physiology. Heart and circulatory physiology 20090301

• Losartan, an Angiotensin type I receptor, restores erectile function by downregulation of cavernous renin-angiotensin system in streptozocin-induced diabetic rats.

  The journal of sexual medicine 20090301

• Influence of sympathetic and AT-receptor blockade on angiotensin II and adrenergic agonist-induced renal vasoconstrictions in spontaneously hypertensive rats.

  Acta physiologica (Oxford, England) 20090301

• Effects of losartan compared with atenolol on lipids in patients with hypertension and left ventricular hypertrophy: the Losartan Intervention For Endpoint reduction in hypertension study.

  Journal of hypertension 20090301

• Effects of allisartan, a new AT(1) receptor blocker, on blood pressure and end-organ damage in hypertensive animals.

  Acta pharmacologica Sinica 20090301

• Relationship between left atrial size and stroke in patients with sinus rhythm and preserved systolic function.

  The Korean journal of internal medicine 20090301

• Review: renal protection by inhibition of the renin-angiotensin-aldosterone system.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20090301

• Local renin-angiotensin system regulates left ventricular hypertrophy induced by swimming training independent of circulating renin: a pharmacological study.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20090301

• [Effects of losartan on left ventricular hypertrophy and plasma transforming growth factor-beta1 in elderly patients with hypertension].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090301

• Fixed-dose manidipine/delapril versus losartan/hydrochlorothiazide in hypertensive patients with type 2 diabetes and microalbuminuria.

  Advances in therapy 20090301

• Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats.

  Journal of hypertension 20090301

• Beneficial effects of the combination of amlodipine and losartan for lowering blood pressure in spontaneously hypertensive rats.

  Archives of pharmacal research 20090301

• [Changes of MMP-2,9 and TIMP-1 expressions in rats with pulmonary arterial hypertension after captopril and losartan interventions].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090301

• Models of cardiovascular disease: measurement of antihypertensive activity in the conscious rat (SHR, DOCA-salt, and Goldblatt hypertension models).

  Current protocols in pharmacology 20090301

• Microinjection of angiotensin II in the caudal ventrolateral medulla induces hyperalgesia.

  Neuroscience 20090218

• Administration of angiotensin II, but not catecholamines, induces accumulation of lipids in the rat heart.

  European journal of pharmacology 20090214

• Effect of the direct Renin inhibitor aliskiren, the Angiotensin receptor blocker losartan, or both on left ventricular mass in patients with hypertension and left ventricular hypertrophy.

  Circulation 20090203

• Hyperbaric oxygen treatment improves GFR in rats with ischaemia/reperfusion renal injury: a possible role for the antioxidant/oxidant balance in the ischaemic kidney.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090201

• Activation of renin-angiotensin system induces osteoporosis independently of hypertension.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20090201

• Effects of high-dose simvastatin therapy on glucose metabolism and ectopic lipid deposition in nonobese type 2 diabetic patients.

  Diabetes care 20090201

• Activation of renal renin-angiotensin system in upstream stimulatory factor 2 transgenic mice.

  American journal of physiology. Renal physiology 20090201

• Renin dynamics in adipose tissue: adipose tissue control of local renin concentrations.

  American journal of physiology. Endocrinology and metabolism 20090201

• Angiotensin-(1-7) activates growth-stimulatory pathways in human mesangial cells.

  American journal of physiology. Renal physiology 20090201

• Renin-angiotensin system and alpha-adducin gene polymorphisms and their relation to responses to antihypertensive drugs: results from the GENRES study.

  American journal of hypertension 20090201

• Regulation of T-cell function by endogenously produced angiotensin II.

  American journal of physiology. Regulatory, integrative and comparative physiology 20090201

• Design of combination angiotensin receptor blocker and angiotensin-converting enzyme inhibitor for treatment of diabetic nephropathy (VA NEPHRON-D).

  Clinical journal of the American Society of Nephrology : CJASN 20090201

• Angiotensin II type 1 receptor-mediated reduction of angiotensin-converting enzyme 2 activity in the brain impairs baroreflex function in hypertensive mice.

  Hypertension (Dallas, Tex. : 1979) 20090201

• [Multi-national clinical trial in circulatory disorders].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090201

• Vascular and metabolic effects of angiotensin II receptor blockers.

  Expert opinion on pharmacotherapy 20090201

• Effects of carvedilol, losartan and trimetazidin on functional parameters of isolated heart of rats at oxidative stress.

  Georgian medical news 20090201

• Molecular imaging for efficacy of pharmacologic intervention in myocardial remodeling.

  JACC. Cardiovascular imaging 20090201

• Anaesthetic Management for Cataract Surgery in VACTERL Syndrome Case Report.

  Indian journal of anaesthesia 20090201

• TRPCs, GPCRs and the Bayliss effect.

  The EMBO journal 20090107

• Short-term electrophysiological effects of losartan, bisoprolol, amlodipine, and hydrochlorothiazide in hypertensive men.

  Annals of medicine 20090101

• Long-term effect of losartan administration on blood pressure, heart and structure of coronary artery of young spontaneously hypertensive rats.

  Physiological research 20090101

• Determination of caveolin-1 in renal caveolar and non-caveolar fractions in experimental type 1 diabetes.

  Physiological research 20090101

• Regulation of oxygen utilization by angiotensin II in chronic kidney disease.

  Kidney international 20090101

• Effect of renin-angiotensin-aldosterone system inhibition, dietary sodium restriction, and/or diuretics on urinary kidney injury molecule 1 excretion in nondiabetic proteinuric kidney disease: a post hoc analysis of a randomized controlled trial.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20090101

• High-affinity interaction of sartans with H+/peptide transporters.

  Drug metabolism and disposition: the biological fate of chemicals 20090101

• A novel type of implantable and programmable infusion pump for small laboratory animals.

  Journal of pharmacological and toxicological methods 20090101

• Liver is the site of splanchnic cortisol production in obese nondiabetic humans.

  Diabetes 20090101

• Losartan, an antagonist of AT1 receptor for angiotensin II, attenuates lipopolysaccharide-induced acute lung injury in rat.

  Archives of biochemistry and biophysics 20090101

• Regression of glomerular injury by losartan in experimental diabetic nephropathy.

  Kidney international 20090101

• Angiotensin II induces vascular endothelial growth factor synthesis in mesenchymal stem cells.

  Experimental cell research 20090101

• Angiotensin II-mediated vasodilation is reduced in adult spontaneously hypertensive rats despite enhanced expression of AT2 receptors.

  Clinical and experimental pharmacology & physiology 20090101

• Blockade of AT1 receptor partially restores vasoreactivity, NOS expression, and superoxide levels in cerebral and carotid arteries of hindlimb unweighting rats.

  Journal of applied physiology (Bethesda, Md. : 1985) 20090101

• Olmesartan reduced microalbuminuria in Japanese subjects with type 2 diabetes.

  Diabetes research and clinical practice 20090101

• Comparison of effects of amlodipine and angiotensin receptor blockers on the intima-media thickness of carotid arterial wall (AAA study: amlodipine vs. ARB in atherosclerosis study).

  Diabetes research and clinical practice 20090101

• Erythropoietin levels in heart failure after an acute myocardial infarction: determinants, prognostic value, and the effects of captopril versus losartan.

  American heart journal 20090101

• Prognostic importance of hemoglobin in hypertensive patients with electrocardiographic left ventricular hypertrophy: the Losartan Intervention For End point reduction in hypertension (LIFE) study.

  American heart journal 20090101

• Inhibition of the renin-angiotensin system: is more better?

  Kidney international 20090101

• Telmisartan is more effective than losartan in reducing proteinuria.

  Kidney international 20090101

• Urotensin II-induced increase in myocardial distensibility is modulated by angiotensin II and endothelin-1.

  Physiological research 20090101

• Kidney injury molecule 1: in search of biomarkers of chronic tubulointerstitial damage and disease progression.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20090101

• Standards of medical care in diabetes--2009.

  Diabetes care 20090101

• Eplerenone decreases inflammatory foci in spontaneously hypertensive rat hearts with minimal effects on blood pressure.

  Journal of cardiovascular pharmacology 20090101

• Role of angiotensin II in the response to endothelin-1 of goat cerebral arteries after ischemia-reperfusion.

  Vascular pharmacology 20090101

• Angiotensin blockade prevents salt-induced injury of the renal circulation in spontaneously hypertensive rats.

  American journal of nephrology 20090101

• Altered expression of Na+ transporters at the mRNA level in rat normal and hypertrophic myocardium.

  Heart and vessels 20090101

• Cardiovascular outcomes in high-risk patients without heart failure treated with ARBs: a systematic review and meta-analysis.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20090101

• Metabolic consequences and vulnerability to diet-induced obesity in male mice under chronic social stress.

  PloS one 20090101

• Cardiac autonomic neuropathy as a predictor of deterioration of the renal function in normoalbuminuric, normotensive patients with type 2 diabetes mellitus.

  Journal of Korean medical science 20090101

• Roles of mitogen-activated protein kinases and angiotensin II in renal development.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20090101

• Myeloid-related protein 8/14 complex describes microcirculatory alterations in patients with type 2 diabetes and nephropathy.

  Cardiovascular diabetology 20090101

• Comparison of therapies between fixed-dose telmisartan/hydrochlorothiazide and losartan/hydrochlorothiazide in patients with mild to moderate hypertension.

  International heart journal 20090101

• Genetic polymorphisms and the risk of accelerated renal function decline in women.

  PloS one 20090101

• Genetic polymorphisms of angiotensin-2 type 1 receptor and angiotensinogen and risk of renal dysfunction and coronary heart disease in type 2 diabetes mellitus.

  BMC nephrology 20090101

• Blood pressure reduction, persistence and costs in the evaluation of antihypertensive drug treatment--a review.

  Cardiovascular diabetology 20090101

• Analysis of published economic evaluations of angiotensin receptor blockers.

  Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20090101

• Angiotensin II directly regulates intestinal epithelial NHE3 in Caco2BBE cells.

  BMC physiology 20090101

• Effects of losartan pretreatment in an experimental model of ischemic acute kidney injury.

  Nephron. Experimental nephrology 20090101

• Losartan decreases p42/44 MAPK signaling and preserves LZ+ MYPT1 expression.

  PloS one 20090101

• Estimating the probability of stroke in Korean hypertensive patients visiting tertiary hospitals using a risk profile from the Framingham study.

  BMC neurology 20090101

• The renin-angiotensin system modulates inflammatory processes in atherosclerosis: evidence from basic research and clinical studies.

  Mediators of inflammation 20090101

• Losartan, an angiotensin-II type 1 receptor blocker, attenuates the liver fibrosis development of non-alcoholic steatohepatitis in the rat.

  BMC research notes 20090101

• Candesartan cilexetil in the treatment of chronic heart failure.

  Vascular health and risk management 20090101

• Arterial stiffness in insulin resistance: the role of nitric oxide and angiotensin II receptors.

  Vascular health and risk management 20090101

• Results of the ONTARGET and TRANSCEND studies: an update and discussion.

  Vascular health and risk management 20090101

• The effect of angiotensin receptor blockers on C-reactive protein and other circulating inflammatory indices in man.

  Vascular health and risk management 20090101

• Effects of candesartan cilexetil on carotid remodeling in hypertensive diabetic patients: the MITEC study.

  Vascular health and risk management 20090101

• Angiotensin receptor blockers for the reduction of proteinuria in diabetic patients with overt nephropathy: results from the AMADEO study.

  Vascular health and risk management 20090101

• Effect of losartan on Doppler sonography indices in kidney transplant patients: a randomized clinical trial.

  Vascular health and risk management 20090101

• [Immunomodulating, metabolic and cardioprotective effects of AT1-angiotensin receptors blocker losartan in patients with coronary heart disease and type 2 diabetes mellitus].

  Terapevticheskii arkhiv 20090101

• Angiotensin II induces inflammatory response partly via toll-like receptor 4-dependent signaling pathway in vascular smooth muscle cells.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101

• Choice of ACE inhibitor combinations in hypertensive patients with type 2 diabetes: update after recent clinical trials.

  Vascular health and risk management 20090101

• Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors.

  Vascular health and risk management 20090101

• Effects of enalapril and losartan in left ventricular remodeling after acute myocardial infarction: a possible mechanism of prevention of cardiac events by angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in high-risk myocardial infarction.

  Internal medicine (Tokyo, Japan) 20090101

• Impact of statins and ACE inhibitors on mortality after COPD exacerbations.

  Respiratory research 20090101

• ACE (I/D) polymorphism and response to treatment in coronary artery disease: a comprehensive database and meta-analysis involving study quality evaluation.

  BMC medical genetics 20090101

• Renin-angiotensin-aldosterone system in the elderly: rational use of aliskiren in managing hypertension.

  Clinical interventions in aging 20090101

• [Involvement of angiotensin on adenosine-induced bronchial hyperreactivity].

  Pneumologia (Bucharest, Romania) 20090101

• Radioligand binding assays: application of [(125)I]angiotensin II receptor binding.

  Methods in molecular biology (Clifton, N.J.) 20090101

• Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats.

  Cardiovascular diabetology 20090101

• Influence of dual blockade of the renin-angiotensin system on thirst in hemodialysis patients.

  Nephron. Clinical practice 20090101

• Pulse pressure, left ventricular function and cardiovascular events during antihypertensive treatment (the LIFE study).

  Blood pressure 20090101

• Reversal of liver fibrosis.

  Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20090101

• Effects of losartan on fibrinolytic parameters and von Willebrand factor in Chinese subjects with hypertension: a comparative study versus atenolol.

  The Journal of international medical research 20090101

• Antiproteinuric effect of angiotensin-converting enzyme inhibitors and an angiotensin II receptor blocker in patients with lupus nephritis.

  The Journal of international medical research 20090101

• Excess of glucocorticoid induces cardiac dysfunction via activating angiotensin II pathway.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101

• Heme oxygenase-1 inducer hemin attenuates the progression of remnant kidney model.

  Nephron. Experimental nephrology 20090101

• Pleiotropic effects of statins in atrial fibrillation patients: the evidence.

  Vascular health and risk management 20090101

• Effect of centrally administered losartan on gastric and duodenal ulcers in rats.

  Pharmacology 20090101

• Valsartan improves endothelial dysfunction in hypertension: a randomized, double-blind study.

  Cardiovascular therapeutics 20090101

• Combination effects of enalapril and losartan on lipid peroxidation in the kidneys of KK-Ay/Ta mice.

  Nephron. Experimental nephrology 20090101

• Biliary pancreatic diversion and laparoscopic adjustable gastric banding in morbid obesity: their long-term effects on metabolic syndrome and on cardiovascular parameters.

  Cardiovascular diabetology 20090101

• High prevalence of undiagnosed chronic kidney disease among at-risk population in Kinshasa, the Democratic Republic of Congo.

  BMC nephrology 20090101

• Serial evaluation of electrocardiographic left ventricular hypertrophy for prediction of risk in hypertensive patients.

  Journal of electrocardiology 20090101

• Two dissimilar AT(1) agonists distinctively activate AT(1) receptors located on the luminal membrane of coronary endothelium.

  Vascular pharmacology 20090101

• Irbesartan improves arterial compliance more than lisinopril.

  Vascular health and risk management 20090101

• One-year renal and cardiac effects of bisoprolol versus losartan in recently diagnosed hypertensive patients: a randomized, double-blind study.

  Clinical drug investigation 20090101

• Gout. Novel therapies for treatment of gout and hyperuricemia.

  Arthritis research & therapy 20090101

• Angiotensins and Alzheimer's disease: a bench to bedside overview.

  Alzheimer's research & therapy 20090101

• Ability to generate patient registries among practices with and without electronic health records.

  Journal of medical Internet research 20090101

• A combined role of calcium channel blockers and angiotensin receptor blockers in stroke prevention.

  Vascular health and risk management 20090101

• Restoration of podocyte structure and improvement of chronic renal disease in transgenic mice overexpressing renin.

  PloS one 20090101

• Hypertensive target organ damage in Ghanaian civil servants with hypertension.

  PloS one 20090101

• Primary prevention using losartan in type 1 diabetic patients significantly reduces retinopathy.

  Cardiovascular journal of Africa 20090101

• Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors.

  Therapeutics and clinical risk management 20090101

• A comparative study of the prevalence of hyperkalemia with the use of angiotensin-converting enzyme inhibitors versus angiotensin receptor blockers.

  Therapeutics and clinical risk management 20090101

• Managing pediatric hepatitis C: current and emerging treatment options.

  Therapeutics and clinical risk management 20090101

• Syncope caused by iatrogenic hyperkalemia.

  Journal of cardiovascular medicine (Hagerstown, Md.) 20090101

• Gout. Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link?

  Arthritis research & therapy 20090101

• [Inhibition of the renin angiotensin system in pregnancy and risk of fetal malformations].

  La Pediatria medica e chirurgica : Medical and surgical pediatrics 20090101

• Cardiac sarcoidosis culminating in severe biventricular failure.

  Case reports in medicine 20090101

• Cardiovascular effects of losartan and its relevant clinical application.

  Current medicinal chemistry 20090101

• Losartan chemistry and its effects via AT1 mechanisms in the kidney.

  Current medicinal chemistry 20090101

• Cardiovascular disease in patients with chronic kidney disease.

  Vascular health and risk management 20090101

• Blood pressure goal achievement with olmesartan medoxomil-based treatment: additional analysis of the OLMEBEST study.

  Vascular health and risk management 20090101

• Angiotensin II receptor blockers in the prevention of complications from atrial fibrillation.

  Vascular health and risk management 20090101

• Drugs associated with more suicidal ideations are also associated with more suicide attempts.

  PloS one 20090101

• Comparative study of vasodilators in an animal model of chronic volume overload caused by severe aortic regurgitation.

  Circulation. Heart failure 20090101

• Diabetic nephropathy.

  Diabetology & metabolic syndrome 20090101

• Kidney transplant in diabetic patients: modalities, indications and results.

  Diabetology & metabolic syndrome 20090101

• [Treatment of patients with arterial hypertension and other stroke risk factors in clinical practice. The PROGNOS program].

  Terapevticheskii arkhiv 20090101

• Animal models for clinical and gestational diabetes: maternal and fetal outcomes.

  Diabetology & metabolic syndrome 20090101

• Management of hypertension in the elderly patient.

  Clinical interventions in aging 20090101

• The role of urate and xanthine oxidase in vascular oxidative stress: future directions.

  Therapeutics and clinical risk management 20090101

• Plasmodium vivax malaria: an unusual presentation.

  Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine 20090101

• The influence of peptides from the angiotensin family on tyrosine kinase activity and cell viability in a human hormone-dependent prostate cancer line.

  Endokrynologia Polska 20090101

• Effects of angiotensin II type-1 receptor blocker losartan on age-related cardiovascular risk in spontaneously hypertensive rats.

  General physiology and biophysics 20090101

• Are angiotensin-converting enzyme inhibitors and angiotensin receptor blockers especially useful for cardiovascular protection?

  Journal of the American Board of Family Medicine : JABFM 20090101

• Resting sinus heart rate and first degree av block: modifiable risk predictors or epiphenomena?

  Indian pacing and electrophysiology journal 20090101

• [Effect of renin-angiotensin system inhibitors on the density of myocardial, pericardial and pulmonary rat mast cells under experimental heart failure].

  Tsitologiia 20090101

• Insights in to the pathogenesis of axial spondyloarthropathy based on gene expression profiles.

  Arthritis research & therapy 20090101

• The use of pre-operative imaging and intraoperative parathyroid hormone level to guide surgical management of tertiary hyperparathyroidism from X-linked hypophosphatemic rickets: a case report.

  Cases journal 20090101

• The rationale and design of the antihypertensives and vascular, endothelial, and cognitive function (AVEC) trial in elderly hypertensives with early cognitive impairment: role of the renin angiotensin system inhibition.

  BMC geriatrics 20090101

• A randomized trial comparing the effect of ramipril and losartan in survivors of ST-elevation myocardial infarction.

  The Journal of international medical research 20090101

• Characterisation of CYP2C8, CYP2C9 and CYP2C19 polymorphisms in a Ghanaian population.

  BMC medical genetics 20090101

• Protective effects of the angiotensin II receptor blocker losartan on cisplatin-induced kidney injury.

  Chemotherapy 20090101

• Review of the treatment of acute coronary syndrome in elderly patients.

  Clinical interventions in aging 20090101

• Mitigating micro-and macro-vascular complications of diabetes beginning in adolescence.

  Vascular health and risk management 20090101

• Comparative assessment of angiotensin receptor blockers in different clinical settings.

  Vascular health and risk management 20090101

• Significance of initial blood pressure and comorbidity for the efficacy of a fixed combination of an angiotensin receptor blocker and hydrochlorothiazide in clinical practice.

  Vascular health and risk management 20090101

• Predictors of cardiovascular events in patients with hypertension and left ventricular hypertrophy: the Losartan Intervention for Endpoint reduction in hypertension study.

  Blood pressure 20090101

• Angiotensin receptor blocker reduces proteinuria independently of blood pressure in children already treated with Angiotensin-converting enzyme inhibitors.

  Kidney & blood pressure research 20090101

• Adolescent type 1 Diabetes Cardio-renal Intervention Trial (AdDIT).

  BMC pediatrics 20090101

• The potential for xanthine oxidase inhibition in the prevention and treatment of cardiovascular and cerebrovascular disease.

  Cardiovascular psychiatry and neurology 20090101

• Management of hypertension with fixed dose combinations of candesartan cilexetil and hydrochlorothiazide: patient perspectives and clinical utility.

  Vascular health and risk management 20090101

• The right ventricle: biologic insights and response to disease.

  Current cardiology reviews 20090101

• Effect of peptide and nonpeptide antagonists of angiotensin II receptors on noradrenaline release in hypothalamus of rats with angiotensin II-induced increase of water intake.

  Pharmacological reports : PR 20090101

• What lies behind serum urate concentration? Insights from genetic and genomic studies.

  Genome medicine 20090101

• Angioedema beyond histamine: an educational case series.

  Acta clinica Belgica 20090101

• New spectrophotometric and fluorimetric methods for determination of fluoxetine in pharmaceutical formulations.

  International journal of analytical chemistry 20090101

• New sensitive kinetic spectrophotometric methods for determination of omeprazole in dosage forms.

  International journal of analytical chemistry 20090101

• Telmisartan: a different angiotensin II receptor blocker protecting a different population?

  The Journal of international medical research 20090101

• Treatment of diabetic vasculopathy with rosiglitazone and ramipril: Hype or hope?

  International journal of diabetes in developing countries 20090101

• PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease.

  PPAR research 20090101

• RP-HPLC Estimation of Ramipril and Telmisartan in Tablets.

  Indian journal of pharmaceutical sciences 20090101

• An evaluation of the efficacy of olmesartan medoxomil in Black patients with hypertension.

  Journal of the American Society of Hypertension : JASH 20090101

• A pharmacovigilance study of antihypertensive medicines at a South delhi hospital.

  Indian journal of pharmaceutical sciences 20090101

• Derivative and Q-analysis Spectrophotometric Methods for Estimation of Hydrochlorothiazide and Olmesartan Medoxomil in Tablets.

  Indian journal of pharmaceutical sciences 20090101

• Simultaneous estimation of amlodipine besilate and olmesartan medoxomil in pharmaceutical dosage form.

  Indian journal of pharmaceutical sciences 20090101

• Exforge (amlodipine/valsartan combination) in hypertension: the evidence of its therapeutic impact.

  Core evidence 20090101

• Febuxostat: the evidence for its use in the treatment of hyperuricemia and gout.

  Core evidence 20090101

• Is there an effective therapy available for non-alcoholic fatty liver disease?

  F1000 medicine reports 20090101

• Combination therapy of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in chronic kidney disease.

  F1000 medicine reports 20090101

• Simultaneous spectrophotometric estimation of Hydrochlorothiazide, Atenolol and Losartan potassium in tablet dosage form.

  Hindustan antibiotics bulletin 20090101

• Telmisartan as a peroxisome proliferator-activated receptor-γ ligand is a new target in the treatment of human renal cell carcinoma.

  Molecular medicine reports 20090101

• Effects of antihypertensive drugs on carotid intima-media thickness: Focus on angiotensin II receptor blockers. A review of randomized, controlled trials.

  Integrated blood pressure control 20090101

• Current concepts in combination therapy for the treatment of hypertension: combined calcium channel blockers and RAAS inhibitors.

  Integrated blood pressure control 20090101

• Angiotensin II augments renal vasoconstriction via AT1 receptors in L-NAME-induced hypertensive rats.

  Proceedings of the Western Pharmacology Society 20090101

• Angiotensin II pressor response in the L-NAME-induced hypertensive pithed rat: role of the AT1 receptor.

  Proceedings of the Western Pharmacology Society 20090101

• Analysis of nine drugs and their cytochrome P450-specific probe metabolites from urine by liquid chromatography-tandem mass spectrometry utilizing sub 2 microm particle size column.

  Journal of chromatography. A 20081226

• Apoptosis-dependent acute pulmonary injury after intratracheal instillation of angiotensin II.

  Sheng li xue bao : [Acta physiologica Sinica] 20081225

• Synthesis and biological activities of novel nonpeptide angiotensin II receptor antagonists based on benzimidazole derivatives bearing a heterocyclic ring.

  Bioorganic & medicinal chemistry 20081215

• Design, synthesis, and evaluation of 5-sulfamoyl benzimidazole derivatives as novel angiotensin II receptor antagonists.

  Bioorganic & medicinal chemistry 20081215

• Molecular imaging of interstitial alterations in remodeling myocardium after myocardial infarction.

  Journal of the American College of Cardiology 20081209

• Gq-coupled receptors as mechanosensors mediating myogenic vasoconstriction.

  The EMBO journal 20081203

• Opposed effects of prostaglandin E2 on perfusion of rat renal cortex and medulla: interactions with the renin-angiotensin system.

  Experimental physiology 20081201

• Angiotensin II type 1 receptor blocker ameliorates uncoupled endothelial nitric oxide synthase in rats with experimental diabetic nephropathy.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081201

• Cost-effectiveness of irbesartan/hydrochlorothiazide in patients with hypertension: an economic evaluation for Sweden.

  Journal of human hypertension 20081201

• N-acetylcysteine abolishes the protective effect of losartan against left ventricular remodeling in cardiomyopathy hamster.

  Antioxidants & redox signaling 20081201

• The effect of different treatment strategies on left atrial size in patients with lone paroxysmal atrial fibrillation-a prospective cohort study.

  Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20081201

• Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis.

  Diabetes 20081201

• Loss of vitamin D receptor produces polyuria by increasing thirst.

  Journal of the American Society of Nephrology : JASN 20081201

• Proteinuria lowering needs a multifactorial and individualized approach to halt progression of renal disease.

  Nature clinical practice. Nephrology 20081201

• Dual inhibition with losartan and aliskiren: a promising therapeutic option for type 2 diabetic nephropathy?

  Nature clinical practice. Nephrology 20081201

• Regulation of ACE2 in cardiac myocytes and fibroblasts.

  American journal of physiology. Heart and circulatory physiology 20081201

• Autoantibodies to the angiotensin type I receptor in response to placental ischemia and tumor necrosis factor alpha in pregnant rats.

  Hypertension (Dallas, Tex. : 1979) 20081201

• Aliskiren combined with losartan: Thor's hammer or Sigurd's sword?

  Current hypertension reports 20081201

• (Pro)renin receptor promotes choroidal neovascularization by activating its signal transduction and tissue renin-angiotensin system.

  The American journal of pathology 20081201

• The role of angiotensin II type 1a receptor on intestinal epithelial cells following small bowel resection in a mouse model.

  Pediatric surgery international 20081201

• Treatment for genetic diseases.

  Current opinion in pediatrics 20081201

• Diabetic state, high plasma insulin and angiotensin II combine to augment endothelin-1-induced vasoconstriction via ETA receptors and ERK.

  British journal of pharmacology 20081201

• The relationship between heart rate reserve and oxygen uptake reserve in heart failure patients on optimized and non-optimized beta-blocker therapy.

  Clinics (Sao Paulo, Brazil) 20081201

• [A case of giant cell microscopic colitis?].

  Annales de pathologie 20081201

• [Mechanisms of losartan for inhibition of myocardial fibrosis following myocardial infarction in rats].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20081201

• Expression of NAD(P)H oxidase subunits and their contribution to cardiovascular damage in aldosterone/salt-induced hypertensive rat.

  Journal of Korean medical science 20081201

• The left atrium, atrial fibrillation, and the risk of stroke in hypertensive patients with left ventricular hypertrophy.

  Therapeutic advances in cardiovascular disease 20081201

• Telmisartan and carotid intima-media thickness regression: a class effect of angiotensin-receptor blockers?

  Hypertension research : official journal of the Japanese Society of Hypertension 20081201

• High dose Losartan and ACE gene polymorphism in IgA nephritis.

  Genomic medicine 20081201

• Renin inhibition with aliskiren in hypertension: focus on aliskiren/hydrochlorothiazide combination therapy.

  Vascular health and risk management 20081201

• Clinical efficacy and safety of olmesartan/hydrochlorothiazide combination therapy in patients with essential hypertension.

  Vascular health and risk management 20081201

• Long-acting nifedipine in the management of the hypertensive patient.

  Vascular health and risk management 20081201

• Pathophysiology of placentation abnormalities in pregnancy-induced hypertension.

  Vascular health and risk management 20081201

• The evolution of systolic blood pressure as a strong predictor of cardiovascular risk and the effectiveness of fixed-dose ARB/CCB combinations in lowering levels of this preferential target.

  Vascular health and risk management 20081201

• Targeting liver myofibroblasts: a novel approach in anti-fibrogenic therapy.

  Hepatology international 20081201

• Safety and efficacy of enzyme replacement therapy in the nephropathy of Fabry disease.

  Biologics : targets & therapy 20081201

• Slower heart rates for healthy hearts: time to redefine tachycardia?

  Circulation. Arrhythmia and electrophysiology 20081201

• Incidence of atrial fibrillation in relation to changing heart rate over time in hypertensive patients: the LIFE study.

  Circulation. Arrhythmia and electrophysiology 20081201

• [Hypertension, hypertensive heart disease and heart failure. Role of loop diuretics].

  Medicina clinica 20081115

• Effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor blockers on lymphangiogenesis of gastric cancer in a nude mouse model.

  Chinese medical journal 20081105

• Impact of left ventricular geometry on prognosis in hypertensive patients with left ventricular hypertrophy (the LIFE study).

  European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology 20081101

• Cytochrome P450 induction by rifampicin in healthy subjects: determination using the Karolinska cocktail and the endogenous CYP3A4 marker 4beta-hydroxycholesterol.

  Clinical pharmacology and therapeutics 20081101

• Aldose reductase genotypes and cardiorenal complications: an 8-year prospective analysis of 1,074 type 2 diabetic patients.

  Diabetes care 20081101

• Excess dietary salt alters angiotensinergic regulation of neurons in the rostral ventrolateral medulla.

  Hypertension (Dallas, Tex. : 1979) 20081101

• Blood pressure control with amlodipine add-on therapy in patients with hypertension and diabetes: results of the Amlodipine Diabetic Hypertension Efficacy Response Evaluation Trial.

  The Annals of pharmacotherapy 20081101

• Estrogen prevents intestinal inflammation after trauma-hemorrhage via downregulation of angiotensin II and angiotensin II subtype I receptor.

  American journal of physiology. Gastrointestinal and liver physiology 20081101

• ADMA impairs nitric oxide-mediated arteriolar function due to increased superoxide production by angiotensin II-NAD(P)H oxidase pathway.

  Hypertension (Dallas, Tex. : 1979) 20081101

• Angiotensin receptor blockers in the treatment of NASH/NAFLD: could they be a first-class option?

  Advances in therapy 20081101

• Nocturia in elderly people with hypertension--no influence of low-dose thiazide added to losartan.

  Journal of the American Geriatrics Society 20081101

• Electrophysiological effects of short-term antihypertensive therapy.

  Expert review of cardiovascular therapy 20081101

• [Effects of angiotensin converting enzyme inhibitors and angiotensin II receptor blockers on angiogenesis of gastric cancer in a nude mouse model].

  Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20081101

• [Angiotensin II type 2 receptors participate in the regulation of inflammatory cytokine secretion in adult rat hypertrophied cardiomyocytes].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20081101

• The distal aorta in the Marfan syndrome.

  Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20081101

• [The safety of long-term administration of losartan in current clinical practice: a non-intervention NCT-CZ 14/04/LOZ study].

  Vnitrni lekarstvi 20081101

• A randomised, controlled, double-blind, cross-over pilot study assessing the effects of spironolactone, losartan and their combination on heart rate variability and QT dispersion in patients with chronic heart failure.

  Cardiovascular journal of Africa 20081101

• Endothelial progenitor cells dysfunction and senescence: contribution to oxidative stress.

  Current cardiology reviews 20081101

• The role of novel biomarkers of cardiovascular disease in chronic kidney disease: focus on adiponectin and leptin.

  Current cardiology reviews 20081101

• [Losartan's effects on the protein expression of the kidney of spontaneous hypertension rat].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20081101

• Telmisartan prevented cognitive decline partly due to PPAR-gamma activation.

  Biochemical and biophysical research communications 20081024

• Angiotensin II blockade in Marfan's syndrome.

  The New England journal of medicine 20081016

• Angiotensin II blockade in Marfan's syndrome.

  The New England journal of medicine 20081016

• Inhibition of left ventricular remodelling in spontaneously hypertensive rats by G alpha q-protein carboxyl terminus imitation polypeptide GCIP-27 is not entirely dependent on blood pressure.

  Clinical and experimental pharmacology & physiology 20081001

• Involvement of AT(1) angiotensin receptors in the vasomodulatory effect of des-aspartate-angiotensin I in the rat renal vasculature.

  Peptides 20081001

• Uricosuric action of losartan via the inhibition of urate transporter 1 (URAT 1) in hypertensive patients.

  American journal of hypertension 20081001

• The molecular and functional phenotype of glomerular podocytes reveals key features of contractile smooth muscle cells.

  American journal of physiology. Renal physiology 20081001

• Sex differences in angiotensin signaling in bulbospinal neurons in the rat rostral ventrolateral medulla.

  American journal of physiology. Regulatory, integrative and comparative physiology 20081001

• Renin-angiotensin system inhibitors protect against age-related changes in rat liver mitochondrial DNA content and gene expression.

  Experimental gerontology 20081001

• Mitogen-activated protein kinases mediate upregulation of hypothalamic angiotensin II type 1 receptors in heart failure rats.

  Hypertension (Dallas, Tex. : 1979) 20081001

• Inhibition of Ang II and renal sympathetic nerve influence dopamine-and isoprenaline-induced renal haemodynamic changes in normal Wistar-Kyoto and spontaneously hypertensive rats.

  Autonomic & autacoid pharmacology 20081001

• American College Of Endocrinology Pre-Diabetes Consensus Conference: part one.

  Diabetes care 20081001

• Pulsatile stretch induces release of angiotensin II and oxidative stress in human endothelial cells: effects of ACE inhibition and AT1 receptor antagonism.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20081001

• Clinical profile of eprosartan: a different angiotensin II receptor blocker.

  Cardiovascular & hematological agents in medicinal chemistry 20081001

• Effect of unilateral ureteral obstruction and anti-angiotensin II treatment on renal tubule and interstitial cell apoptosis in rats.

  Croatian medical journal 20081001

• [Angiotensin II type 2 receptor expression and its modulation in angiotensin II induced acute lung injury in rat].

  Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20081001

• The relationship between proteinuria and coronary risk: a systematic review and meta-analysis.

  PLoS medicine 20081001

• Effects of early losartan therapy on ventricular late potentials in acute myocardial infarction.

  Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20081001

• [Effects of fosinopril and losartan on the expression of Toll- like receptor 4 in renal tubular epithelia cells].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20081001

• The importance of home blood pressure measurement for preventing stroke and cardiovascular disease in hypertensive patients: a sub-analysis of the Japan Hypertension Evaluation with Angiotensin II Antagonist Losartan Therapy (J-HEALTH) study, a prospective nationwide observational study.

  Hypertension research : official journal of the Japanese Society of Hypertension 20081001

• The renin angiotensin system in the development of cardiovascular disease: role of aliskiren in risk reduction.

  Vascular health and risk management 20081001

• [C1q nephropathy. Report of one case].

  Revista medica de Chile 20081001

• [The pleiotropic effects of losartan--the importance of decreasing uric acid level].

  Lege artis medicinae : uj magyar orvosi hirmondo 20081001

• Nephrotic range proteinuria in c-ANCA-positive crescentic glomerulonephritis with linear immune deposits.

  Indian journal of nephrology 20081001

• Neuropharmacology.

  Indian journal of pharmacology 20081001

• Clinical pharmacology.

  Indian journal of pharmacology 20081001

• The human UDP-glucuronosyltransferase UGT1A3 is highly selective towards N2 in the tetrazole ring of losartan, candesartan, and zolarsartan.

  Biochemical pharmacology 20080915

• Human brain contains a novel non-AT1, non-AT2 binding site for active angiotensin peptides.

  Life sciences 20080912

• Multi-syringe chromatography (MSC) system for the on-line solid-phase extraction and determination of hydrochlorothiazide and losartan potassium in superficial water, groundwater and wastewater outlet samples.

  Journal of pharmaceutical and biomedical analysis 20080910

• Aliskiren combined with losartan in diabetes and nephropathy.

  The New England journal of medicine 20080904

• Aliskiren combined with losartan in diabetes and nephropathy.

  The New England journal of medicine 20080904

• Aliskiren combined with losartan in diabetes and nephropathy.

  The New England journal of medicine 20080904

• Aliskiren combined with losartan in diabetes and nephropathy.

  The New England journal of medicine 20080904

• Angiotensin II--AT1 receptor antagonists: design, synthesis and evaluation of substituted carboxamido benzimidazole derivatives.

  European journal of medicinal chemistry 20080901

• Cross-talk between cytokines and renin-angiotensin in hypothalamic paraventricular nucleus in heart failure: role of nuclear factor-kappaB.

  Cardiovascular research 20080901

• MAPK and angiotensin II receptor in kidney of newborn rats from losartan-treated dams.

  Pediatric nephrology (Berlin, Germany) 20080901

• Enalapril and losartan are more effective than carvedilol in preventing dilated cardiomyopathy in the Syrian cardiomyopathic hamster.

  Journal of cardiovascular pharmacology and therapeutics 20080901

• Effect of pentoxifylline in addition to losartan on proteinuria and GFR in CKD: a 12-month randomized trial.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20080901

• Do drugs that block transforming growth factor beta reduce posthaemorrhagic ventricular dilatation in a neonatal rat model?

  Acta paediatrica (Oslo, Norway : 1992) 20080901

• Identifying patterns of adverse event reporting for four members of the angiotensin II receptor blockers class of drugs: revisiting the Weber effect.

  Pharmacoepidemiology and drug safety 20080901

• ACE gene polymorphism and the prognosis and treatment of overt diabetic nephropathy.

  Nature clinical practice. Nephrology 20080901

• Effect of angiotensin receptor blockers on cardiovascular events in patients undergoing hemodialysis: an open-label randomized controlled trial.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20080901

• Interaction between cardiac sympathetic afferent reflex and chemoreflex is mediated by the NTS AT1 receptors in heart failure.

  American journal of physiology. Heart and circulatory physiology 20080901

• Effects of losartan on serum total and high-molecular weight adiponectin concentrations in hypertensive patients with metabolic syndrome.

  Metabolism: clinical and experimental 20080901

• Design of the heart failure endpoint evaluation of AII-antagonist losartan (HEAAL) study in patients intolerant to ACE-inhibitor.

  European journal of heart failure 20080901

• All clinical trials are not created equal: The dilemma of HEAAL.

  European journal of heart failure 20080901

• Effect of losartan on cyclooxygenase-2 expression in normal human mesangial cells and kidneys of rats with diabetic nephropathy.

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20080901

• [The effect of losartan on glomerular sclerosis in rats with diabetic nephropathy].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20080901

• Low-dose losartan therapy reduces proteinuria in normotensive patients with immunoglobulin A nephropathy.

  Hypertension research : official journal of the Japanese Society of Hypertension 20080901

• Comparison of losartan and carvedilol on attenuating inflammatory and oxidative response and preserving energy transcription factors and left ventricular function in dilated cardiomyopathy rats.

  International heart journal 20080901

• Inhibitory effects of benzyl benzoate and its derivatives on angiotensin II-induced hypertension.

  Bioorganic & medicinal chemistry 20080815

• [A 60-year-old man with heart failure, dry cough and elevated INR values].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20080814

• Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy.

  Pediatric nephrology (Berlin, Germany) 20080801

• Using nurses and office staff to report prescribing errors in primary care.

  International journal for quality in health care : journal of the International Society for Quality in Health Care 20080801

• Oestrogenic influence on brain AT1 receptor signalling on the thirst and sodium appetite in osmotically stimulated and sodium-depleted female rats.

  Experimental physiology 20080801

• Preventing left ventricular hypertrophy by ACE inhibition in hypertensive patients with type 2 diabetes: a prespecified analysis of the Bergamo Nephrologic Diabetes Complications Trial (BENEDICT).

  Diabetes care 20080801

• ACE-dependent and chymase-dependent angiotensin II generation in normal and glucose-stimulated human mesangial cells.

  Experimental biology and medicine (Maywood, N.J.) 20080801

• AT1 receptor participates in the cardiac hypertrophy induced by resistance training in rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080801

• Telmisartan is more effective than losartan in reducing proteinuria in patients with diabetic nephropathy.

  Kidney international 20080801

• Renin-angiotensin system blockade is effective in reducing proteinuria of patients with progressive nephropathy caused by MYH9 mutations (Fechtner-Epstein syndrome).

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080801

• Regulation of myosin light chain kinase expression by angiotensin II in hypertension.

  American journal of hypertension 20080801

• A multivariate approach for the simultaneous determination of losartan potassium and hydrochlorothiazide in a combined pharmaceutical tablet formulation.

  Analytical and bioanalytical chemistry 20080801

• Increased colonic sodium absorption in rats with chronic renal failure is partially mediated by AT1 receptor agonism.

  American journal of physiology. Gastrointestinal and liver physiology 20080801

• Hypercholesterolaemia exacerbates ventricular remodelling after myocardial infarction in the rat: role of angiotensin II type 1 receptors.

  British journal of pharmacology 20080801

• Angiotensin II receptor blockade administered after injury improves muscle regeneration and decreases fibrosis in normal skeletal muscle.

  The American journal of sports medicine 20080801

• Differential mechanisms of angiotensin II and PDGF-BB on migration and proliferation of coronary artery smooth muscle cells.

  Journal of molecular and cellular cardiology 20080801

• Angiotensin II-triggered p44/42 mitogen-activated protein kinase mediates sympathetic excitation in heart failure rats.

  Hypertension (Dallas, Tex. : 1979) 20080801

• Area-specific differences in transmitter release in central catecholaminergic neurons of spontaneously hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 20080801

• Marked regional left ventricular heterogeneity in hypertensive left ventricular hypertrophy patients: a losartan intervention for endpoint reduction in hypertension (LIFE) cardiovascular magnetic resonance and echocardiographic substudy.

  Hypertension (Dallas, Tex. : 1979) 20080801

• Prescribing patterns in hypertension: the emerging role of fixed-dose combinations for attaining BP goals in hypertensive patients.

  Current medical research and opinion 20080801

• ADMA induces monocyte adhesion via activation of chemokine receptors in cultured THP-1 cells.

  Cytokine 20080801

• Autoantibody against AT1 receptor from preeclamptic patients induces vasoconstriction through angiotensin receptor activation.

  Journal of hypertension 20080801

• Telmisartan is a potent target for prevention and treatment in human prostate cancer.

  Oncology reports 20080801

• Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice.

  Nature medicine 20080801

• Phospholipase C/protein kinase C pathway mediates angiotensin II-dependent apoptosis in neonatal rat cardiac fibroblasts expressing AT1 receptor.

  Journal of cardiovascular pharmacology 20080801

• Angiotensin II type 2 receptor-mediated inhibition of norepinephrine release in isolated rat hearts.

  Journal of cardiovascular pharmacology 20080801

• Heart rate dynamics during a treadmill cardiopulmonary exercise test in optimized beta-blocked heart failure patients.

  Clinics (Sao Paulo, Brazil) 20080801

• RAS inhibitors decrease apoptosis of acinar cells and increase elimination of pancreatic stellate cells after in the course of experimental chronic pancreatitis induced by dibutyltin dichloride.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080801

• Disposition of a CYP2C9 phenotyping agent, losartan, is not influenced by the common 3435C > T variation of the drug transporter gene ABCB1 (MDR1).

  Basic & clinical pharmacology & toxicology 20080801

• Genetic variations of CYP2C9 in 724 Japanese individuals and their impact on the antihypertensive effects of losartan.

  Hypertension research : official journal of the Japanese Society of Hypertension 20080801

• Losartan elevates the serum high-molecular weight-adiponectin isoform and concurrently improves insulin sensitivity in patients with impaired glucose metabolism.

  Hypertension research : official journal of the Japanese Society of Hypertension 20080801

• The renin-angiotensin system and diabetes: an update.

  Vascular health and risk management 20080801

• Fixed combinations in the management of hypertension: perspectives on lercanidipine-enalapril.

  Vascular health and risk management 20080801

• Silent myocardial infarction in women with type II diabetes mellitus and microalbuminuria.

  Therapeutics and clinical risk management 20080801

• Characterization of angiotensin II antagonism displayed by Ib, a novel nonpeptide angiotensin AT(1) receptor antagonist.

  European journal of pharmacology 20080728

• [Effects of long-term antihypertensive therapy with losartan on blood pressure and cognitive function in patients with essential hypertension and other cerebrovascular risk factors (AWARE observational study)].

  Medizinische Klinik (Munich, Germany : 1983) 20080715

• Blood pressure lowering effects of niacin-bound chromium(III) (NBC) in sucrose-fed rats: renin-angiotensin system.

  Journal of inorganic biochemistry 20080701

• Calcium-independent and 1,25(OH)2D3-dependent regulation of the renin-angiotensin system in 1alpha-hydroxylase knockout mice.

  Kidney international 20080701

• The prognostic value of the ECG in hypertension: where are we now?

  Journal of human hypertension 20080701

• Regression of glomerulosclerosis in subtotally nephrectomized rats: effects of monotherapy with losartan, spironolactone, and their combination.

  American journal of physiology. Renal physiology 20080701

• Angiotensin and NMDA receptors in the median preoptic nucleus mediate hemodynamic response patterns to stress.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080701

• The effect of angiotensin II on intracellular pH is mediated by AT(1) receptor translocation.

  American journal of physiology. Cell physiology 20080701

• Stepwise screening for diabetes identifies people with high but modifiable coronary heart disease risk. The ADDITION study.

  Diabetologia 20080701

• Upregulation of AT2 receptor and iNOS impairs angiotensin II-induced contraction without endothelium influence in young normotensive diabetic rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080701

• Intradermal angiotensin II administration attenuates the local cutaneous vasodilator heating response.

  American journal of physiology. Heart and circulatory physiology 20080701

• Modulating an oxidative-inflammatory cascade: potential new treatment strategy for improving glucose metabolism, insulin resistance, and vascular function.

  International journal of clinical practice 20080701

• Angiotensin II relaxations of bovine adrenal cortical arteries: role of angiotensin II metabolites and endothelial nitric oxide.

  Hypertension (Dallas, Tex. : 1979) 20080701

• Simultaneous determination of hydrochlorothiazide and losartan potassium in tablets by high-performance low-pressure chromatography using a multi-syringe burette coupled to a monolithic column.

  Analytical and bioanalytical chemistry 20080701

• Gender differences in regression of electrocardiographic left ventricular hypertrophy during antihypertensive therapy.

  Hypertension (Dallas, Tex. : 1979) 20080701

• Hypertension induces somatic cellular senescence in rats and humans by induction of cell cycle inhibitor p16INK4a.

  Hypertension (Dallas, Tex. : 1979) 20080701

• Left atrial systolic force in hypertensive patients with left ventricular hypertrophy: the LIFE study.

  Journal of hypertension 20080701

• Losartan and ozagrel reverse retinal arteriolar constriction in non-obese diabetic mice.

  Microcirculation (New York, N.Y. : 1994) 20080701

• Reduction of proteinuria with angiotensin receptor blockers.

  Nature clinical practice. Cardiovascular medicine 20080701

• Angiotensin II regulates liver regeneration via type 1 receptor following partial hepatectomy in mice.

  Biological & pharmaceutical bulletin 20080701

• Targeting TGF-beta and the extracellular matrix in Marfan's syndrome.

  Developmental cell 20080701

• Comparative analysis of renal protein expression in spontaneously hypertensive rat.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20080701

• Angiotensin II blockade and aortic-root dilation in Marfan's syndrome.

  The New England journal of medicine 20080626

• A small molecule for a large disease.

  The New England journal of medicine 20080626

• Inhibition of Angiotensin II receptors during pregnancy induces malformations in developing rat kidney.

  European journal of pharmacology 20080624

• The trafficking protein GABARAP binds to and enhances plasma membrane expression and function of the angiotensin II type 1 receptor.

  Circulation research 20080620

• Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome.

  European journal of pharmacology 20080610

• Aliskiren combined with losartan in type 2 diabetes and nephropathy.

  The New England journal of medicine 20080605

• Aliskiren and dual therapy in type 2 diabetes mellitus.

  The New England journal of medicine 20080605

• Angiotensin II-induced contractions in human jejunal wall musculature in vitro.

  Acta physiologica (Oxford, England) 20080601

• Exercise training combined with angiotensin II receptor blockade limits post-infarct ventricular remodelling in rats.

  Cardiovascular research 20080601

• COX-2 expression stimulated by Angiotensin II depends upon AT1 receptor internalization in vascular smooth muscle cells.

  Biochimica et biophysica acta 20080601

• Angiotensin II upregulates LDL receptor-related protein (LRP1) expression in the vascular wall: a new pro-atherogenic mechanism of hypertension.

  Cardiovascular research 20080601

• Urinary kallikrein excretion is related to renal function change and inflammatory status in chronic kidney disease patients receiving angiotensin II receptor blocker treatment.

  Nephrology (Carlton, Vic.) 20080601

• Renin-angiotensin system blockade is renoprotective in immune complex-mediated glomerulonephritis.

  Journal of the American Society of Nephrology : JASN 20080601

• Direct renin inhibition: clinical pharmacology.

  Journal of molecular medicine (Berlin, Germany) 20080601

• Enzyme-assisted synthesis and structure characterization of glucuronic acid conjugates of losartan, candesartan, and zolarsartan.

  Bioorganic chemistry 20080601

• Angiotensin II type 1 receptor blocker preserves tolerance to ischemia-reperfusion injury in Dahl salt-sensitive rat heart.

  American journal of physiology. Heart and circulatory physiology 20080601

• AT1 blockade during lactation as a model of chronic nephropathy: mechanisms of renal injury.

  American journal of physiology. Renal physiology 20080601

• Contractility of placental vascular smooth muscle cells in response to stimuli produced by the placenta: roles of ACE vs. non-ACE and AT1 vs. AT2 in placental vessel cells.

  Placenta 20080601

• Hypertension impairs postnatal vasculogenesis: role of antihypertensive agents.

  Hypertension (Dallas, Tex. : 1979) 20080601

• Change in pulse pressure/stroke index in response to sustained blood pressure reduction and its impact on left ventricular mass and geometry changes: the life study.

  American journal of hypertension 20080601

• Effect of ANG II on endothelial cell apoptosis and survival and its impact on skeletal muscle angiogenesis after electrical stimulation.

  American journal of physiology. Heart and circulatory physiology 20080601

• Telmisartan increases fatty acid oxidation in skeletal muscle through a peroxisome proliferator-activated receptor-gamma dependent pathway.

  Journal of hypertension 20080601

• Left bundle branch block and cardiovascular morbidity and mortality in hypertensive patients with left ventricular hypertrophy: the Losartan Intervention For Endpoint Reduction in Hypertension study.

  Journal of hypertension 20080601

• Laboratory tests as predictors of the antihypertensive effects of amlodipine, bisoprolol, hydrochlorothiazide and losartan in men: results from the randomized, double-blind, crossover GENRES Study.

  Journal of hypertension 20080601

• ETA-receptor blockade impairs vasoconstriction after hemorrhage in xenon-anesthetized dogs treated with an AT1-receptor antagonist.

  Canadian journal of physiology and pharmacology 20080601

• [The effect of losartan on the intima-media thickness of carotid artery].

  Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20080601

• Losartan reduced connexin43 expression in left ventricular myocardium of spontaneously hypertensive rats.

  Journal of Zhejiang University. Science. B 20080601

• Agonistic AT(1) receptor autoantibody increases in serum of patients with refractory hypertension and improves Ca(2+) mobilization in cultured rat vascular smooth muscle cells.

  Cellular & molecular immunology 20080601

• [Perindopril and losartan attenuate bleomycin A5-induced pulmonary fibrosis in rats].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080601

• Effect of losartan on exercise tolerance and echocardiographic parameters in patients with mitral regurgitation.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20080601

• Intracellular and extracellular renin have opposite effects on the regulation of heart cell volume. Implications for myocardial ischaemia.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20080601

• Angiotensin II-stimulated collagen synthesis in aortic adventitial fibroblasts is mediated by connective tissue growth factor.

  Hypertension research : official journal of the Japanese Society of Hypertension 20080601

• [Prevention of left ventricular remodeling after myocardial infarction: efficacy of physical training].

  Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20080601

• Fibrosis in diabetes complications: pathogenic mechanisms and circulating and urinary markers.

  Vascular health and risk management 20080601

• The secretory phospholipase A2 group IIA: a missing link between inflammation, activated renin-angiotensin system, and atherogenesis?

  Vascular health and risk management 20080601

• Fixed combinations in the management of hypertension: patient perspectives and rationale for development and utility of the olmesartan-amlodipine combination.

  Vascular health and risk management 20080601

• [Serum uric acid prevalence and changes post various antihypertensive agents in patients with essential hypertension].

  Zhonghua xin xue guan bing za zhi 20080601

• Administration of angiotensin II in the paraventricular nucleus protects gastric mucosa from ischemia-reperfusion injury.

  Brain research 20080530

• A case of parkinsonism worsened by losartan: a probable new adverse effect.

  Movement disorders : official journal of the Movement Disorder Society 20080515

• Losartan improves impaired nitric oxide synthase-dependent dilatation of cerebral arterioles in type 1 diabetic rats.

  Brain research 20080513

• The effects of losartan on signal-averaged P wave in patients with atrial fibrillation.

  International journal of cardiology 20080507

• Anti-inflammatory and anti-oxidant properties of telmisartan in cultured human umbilical vein endothelial cells.

  Atherosclerosis 20080501

• Combination of phenotype assessments and CYP2C9-VKORC1 polymorphisms in the determination of warfarin dose requirements in heavily medicated patients.

  Clinical pharmacology and therapeutics 20080501

• Anti-inflammatory effect of angiotensin type 1 receptor antagonist on endotoxin-induced uveitis in rats.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20080501

• A novel adipokine CTRP1 stimulates aldosterone production.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080501

• Effects of dietary sodium and hydrochlorothiazide on the antiproteinuric efficacy of losartan.

  Journal of the American Society of Nephrology : JASN 20080501

• Characterization of a functional (pro)renin receptor in rat brain neurons.

  Experimental physiology 20080501

• Therapeutic strategies to slow chronic kidney disease progression.

  Pediatric nephrology (Berlin, Germany) 20080501

• L-arginine-induced glomerular hyperfiltration response: the roles of insulin and ANG II.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080501

• High doses of lercanidipine are better tolerated than other dihydropyridines in hypertensive patients with metabolic syndrome: results from the TOLERANCE study.

  International journal of clinical practice 20080501

• Effective management of hypertension with dihydropyridine calcium channel blocker-based combination therapy in patients at high cardiovascular risk.

  International journal of clinical practice 20080501

• Angiotensin II up-regulates angiotensin I-converting enzyme (ACE), but down-regulates ACE2 via the AT1-ERK/p38 MAP kinase pathway.

  The American journal of pathology 20080501

• Inhibition of the rapid component of the delayed rectifier potassium current in ventricular myocytes by angiotensin II via the AT1 receptor.

  British journal of pharmacology 20080501

• Prevention of salt-induced hypertension and fibrosis by AT1-receptor blockers in Dahl S rats.

  Journal of cardiovascular pharmacology 20080501

• Meta-analysis of randomized controlled trials comparing telmisartan with losartan in the treatment of patients with hypertension.

  American journal of hypertension 20080501

• [Primary and secondary Raynaud's phenomenon].

  Zeitschrift fur Rheumatologie 20080501

• Comparison of rate and rhythm control in hypertension patients with atrial fibrillation.

  Circulation journal : official journal of the Japanese Circulation Society 20080501

• Angiotensin-(1-7) has a dual role on growth-promoting signalling pathways in rat heart in vivo by stimulating STAT3 and STAT5a/b phosphorylation and inhibiting angiotensin II-stimulated ERK1/2 and Rho kinase activity.

  Experimental physiology 20080501

• [Systemic sclerosis].

  Medizinische Monatsschrift fur Pharmazeuten 20080501

• [Experimental study on losartan decreasing denervated skeletal muscle atrophy through reducing cell apoptosis].

  Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20080501

• [Transient renal failure in a newborn due angiotensin receptor II antagonist use during pregnancy: report of a case].

  Revista medica de Chile 20080501

• Noninvasive imaging of angiotensin receptors after myocardial infarction.

  JACC. Cardiovascular imaging 20080501

• [Effect of micro-injection angiotensin II into subfornical organ in rats on Na+, K(+)-ATPase activity in proximal tubules].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20080501

• Inhibition of renin angiotensin system decreases renal protein oxidative damage in diabetic rats.

  Biochemical and biophysical research communications 20080411

• Angiotensin II induces matrix metalloproteinase-9 expression via a nuclear factor-kappaB-dependent pathway in vascular smooth muscle cells.

  Regulatory peptides 20080410

• Design, synthesis, and biological evaluation of AT1 angiotensin II receptor antagonists based on the pyrazolo[3,4-b]pyridine and related heteroaromatic bicyclic systems.

  Journal of medicinal chemistry 20080410

• Medical management of small abdominal aortic aneurysms.

  Circulation 20080408

• Parathyroid hormone-related protein promotes inflammation in the kidney with an obstructed ureter.

  Kidney international 20080401

• ACE gene polymorphism and losartan treatment in type 2 diabetic patients with nephropathy.

  Journal of the American Society of Nephrology : JASN 20080401

• Hyperinsulinemic rats are normotensive but sensitized to angiotensin II.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080401

• Intracellular ANG II directly induces in vitro transcription of TGF-beta1, MCP-1, and NHE-3 mRNAs in isolated rat renal cortical nuclei via activation of nuclear AT1a receptors.

  American journal of physiology. Cell physiology 20080401

• Gender differences in left ventricular structure and function during antihypertensive treatment: the Losartan Intervention for Endpoint Reduction in Hypertension Study.

  Hypertension (Dallas, Tex. : 1979) 20080401

• Prenatal gender-related nicotine exposure increases blood pressure response to angiotensin II in adult offspring.

  Hypertension (Dallas, Tex. : 1979) 20080401

• Effects of losartan in women with hypertension and left ventricular hypertrophy: results from the Losartan Intervention for Endpoint Reduction in Hypertension Study.

  Hypertension (Dallas, Tex. : 1979) 20080401

• Role of angiotensin II in the enhancement of ammonia production and secretion by the proximal tubule in metabolic acidosis.

  American journal of physiology. Renal physiology 20080401

• Time-course reduction of renal function in rats on high sodium intake: acute reversal by potassium canrenoate.

  Clinical and experimental pharmacology & physiology 20080401

• Renin inhibition with aliskiren.

  Clinical and experimental pharmacology & physiology 20080401

• Cardioprotection and kallikrein-kinin system in acute myocardial ischaemia in mice.

  Clinical and experimental pharmacology & physiology 20080401

• Current concepts: renin inhibition in the treatment of hypertension.

  Current opinion in pharmacology 20080401

• Clinical impact of 'in-treatment' wall motion abnormalities in hypertensive patients with left ventricular hypertrophy: the LIFE study.

  Journal of hypertension 20080401

• Efficacy of manidipine/delapril versus losartan/hydrochlorothiazide fixed combinations in patients with hypertension and diabetes.

  Journal of hypertension 20080401

• A double-blind, randomized study evaluating losartan potassium monotherapy or in combination with hydrochlorothiazide versus placebo in obese patients with hypertension.

  Current medical research and opinion 20080401

• Medical treatment of Marfan syndrome: a time for change.

  Heart (British Cardiac Society) 20080401

• Coronary constriction to angiotensin II is enhanced by endothelial superoxide production in sheep programmed by dexamethasone.

  Pediatric research 20080401

• Rationale and design of a study to examine lower targets for low-density lipoprotein-cholesterol and blood pressure in coronary artery disease patients.

  Circulation journal : official journal of the Japanese Circulation Society 20080401

• Angiotensin II activates myostatin expression in cultured rat neonatal cardiomyocytes via p38 MAP kinase and myocyte enhance factor 2 pathway.

  The Journal of endocrinology 20080401

• [Other antihyperuricemic agents].

  Nihon rinsho. Japanese journal of clinical medicine 20080401

• Both enalapril and losartan attenuate sarcolemmal Na+-K+-ATPase remodeling in failing rat heart due to myocardial infarction.

  Canadian journal of physiology and pharmacology 20080401

• Reduced levels of cyclic AMP contribute to the enhanced oxidative stress in vascular smooth muscle cells from spontaneously hypertensive rats.

  Canadian journal of physiology and pharmacology 20080401

• Effects of long-term losartan and L-arginine treatment on haemodynamics, glomerular filtration, and SOD activity in spontaneously hypertensive rats.

  Canadian journal of physiology and pharmacology 20080401

• Effects of antihypertensive drugs on capillary rarefaction in spontaneously hypertensive rats: intravital microscopy and histologic analysis.

  Journal of cardiovascular pharmacology 20080401

• Aliskiren: new drug. Arterial hypertension: no evidence of clinical efficacy.

  Prescrire international 20080401

• Low dose of losartan decreased urinary excretions of IgG, transferrin, and ceruloplasmin without reducing albuminuria in normoalbuminuric type 2 diabetic patients.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20080401

• Early detection and management of the high-risk patient with elevated blood pressure.

  Vascular health and risk management 20080401

• Orlistat in the prevention of diabetes in the obese patient.

  Vascular health and risk management 20080401

• Comparison of angiotensin converting enzyme inhibition and angiotensin II receptor blockade for the prevention of experimental autoimmune myocarditis.

  International journal of cardiology 20080328

• Synthesis and antihypertensive effects of new methylthiomorpholinphenol derivatives.

  European journal of medicinal chemistry 20080301

• Involvement of uric acid transporters in alteration of serum uric acid level by angiotensin II receptor blockers.

  Pharmaceutical research 20080301

• Losartan attenuates ventilator-induced lung injury.

  The Journal of surgical research 20080301

• Low NaCl intake elevates renal medullary endothelin-1 and endothelin A (ETA) receptor mRNA but not the sensitivity of renal Na+ excretion to ETA receptor blockade in rats.

  Acta physiologica (Oxford, England) 20080301

• Hypertension in children with chronic kidney disease: pathophysiology and management.

  Pediatric nephrology (Berlin, Germany) 20080301

• A biological approach in a patient with psoriasis and bullous pemphigoid associated with losartan therapy.

  Clinical and experimental dermatology 20080301

• Effect of LDL cholesterol and treatment with losartan on end-stage renal disease in the RENAAL study.

  Diabetes care 20080301

• The effect of losartan on hemoglobin concentration and renal outcome in diabetic nephropathy of type 2 diabetes.

  Kidney international 20080301

• Cardiovascular reactivity after blockade of angiotensin AT1 receptors in the experimental model of tilting test in conscious rats.

  British journal of pharmacology 20080301

• Impaired responsiveness of renal sensory nerves in streptozotocin-treated rats and obese Zucker diabetic fatty rats: role of angiotensin.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080301

• Evaluation of the clinical outcomes of switching patients from atorvastatin to simvastatin and losartan to candesartan in a primary care setting: 2 years on.

  International journal of clinical practice 20080301

• Combination of the electrocardiographic strain pattern and albuminuria for the prediction of new-onset heart failure in hypertensive patients: the LIFE study.

  American journal of hypertension 20080301

• Meconium increases type 1 angiotensin II receptor expression and alveolar cell death.

  Pediatric research 20080301

• Peroxisome proliferator-activated receptor alpha activation attenuated angiotensin type 1-mediated but enhanced angiotensin type 2-mediated hemodynamic effects to angiotensin II in the rat.

  Journal of hypertension 20080301

• Renin-angiotensin system component expression in the HL-1 atrial cell line and in a pig model of atrial fibrillation.

  Journal of hypertension 20080301

• Anti-cancer actions of a recombinant antibody (R6313/G2) against the angiotensin II AT1 receptor.

  Endocrine-related cancer 20080301

• Analysis of the vasorelaxant action of angiotensin II in the isolated rat renal artery.

  Journal of pharmacological sciences 20080301

• Changing dietary sodium alters the chronic cardiovascular effects of losartan in rats.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20080301

• Cough induced by losartan with resolution after substitution with enalapril.

  Clinical therapeutics 20080301

• [Clinical trials of ACE inhibitors and ARB for treatment of patients with hypertension, heart failure, and diabetic nephropathy in Japan--special reference to the dosage schedule and adverse effects].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20080301

• Antidepressant activity of fosinopril, ramipril and losartan, but not of lisinopril in depressive paradigms of albino rats and mice.

  Indian journal of experimental biology 20080301

• Pulmonary hypertension associated with COPD.

  International journal of chronic obstructive pulmonary disease 20080301

• Pathological regression by angiotensin II type 1 receptor blockade in patients with mesangial proliferative glomerulonephritis.

  Hypertension research : official journal of the Japanese Society of Hypertension 20080301

• Impact of blood pressure control on cardiovascular events in 26,512 Japanese hypertensive patients: the Japan Hypertension Evaluation with Angiotensin II Antagonist Losartan Therapy (J-HEALTH) study, a prospective nationwide observational study.

  Hypertension research : official journal of the Japanese Society of Hypertension 20080301

• Upregulation of interleukin-8/CXCL8 in vascular smooth muscle cells from spontaneously hypertensive rats.

  Hypertension research : official journal of the Japanese Society of Hypertension 20080301

• Effects of angiotensin converting enzyme inhibitor and angiotensin II receptor antagonist combination on nitric oxide bioavailability and atherosclerotic change in Watanabe heritable hyperlipidemic rabbits.

  Hypertension research : official journal of the Japanese Society of Hypertension 20080301

• [The effect of ginsenoside Rg1 on the renal interstitial fibrosis of UUO rat].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20080301

• Patterns of left ventricular hypertrophy in essential hypertension: should echocardiography guide the pharmacological treatment?

  International journal of cardiology 20080227

• Brazilein-induced contraction of rat arterial smooth muscle involves activation of Ca2+ entry and ROK, ERK pathways.

  European journal of pharmacology 20080212

• Cardiovascular expression of inflammatory signaling molecules, the kinin B1 receptor and COX2, in the rabbit: effects of LPS, anti-inflammatory and anti-hypertensive drugs.

  Regulatory peptides 20080207

• Letter regarding article by Hood et al, 'The Spironolactone, Amiloride, Losartan, and Thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio'.

  Circulation 20080205

• Crosstalk between angiotensin II and platelet derived growth factor-BB mediated signal pathways in cardiomyocytes.

  Chinese medical journal 20080205

• Matrix metalloproteinase gene delivery for liver fibrosis.

  Pharmaceutical research 20080201

• Angiotensin II AT1 receptor blockade normalizes CD11b+ monocyte production in bone marrow of hypercholesterolemic monkeys.

  Atherosclerosis 20080201

• Inhibition of the renin-angiotensin system attenuates the development of liver fibrosis and oxidative stress in rats.

  Clinical and experimental pharmacology & physiology 20080201

• ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin.

  The European respiratory journal 20080201

• Angiotensin II-mediated oxidative DNA damage accelerates cellular senescence in cultured human vascular smooth muscle cells via telomere-dependent and independent pathways.

  Circulation research 20080201

• Angiotensin converting enzyme inhibitor but not angiotensin receptor blockade or statin ameliorates murine adriamycin nephropathy.

  Kidney international 20080201

• In vivo regulation of AT1a receptor-mediated intracellular uptake of [125I]Val5-ANG II in the kidneys and adrenals of AT1a receptor-deficient mice.

  American journal of physiology. Renal physiology 20080201

• Overexpression of angiotensinogen increases tubular apoptosis in diabetes.

  Journal of the American Society of Nephrology : JASN 20080201

• Role of the renin angiotensin system in TNF-alpha and Shiga-toxin-induced tissue factor expression.

  Pediatric nephrology (Berlin, Germany) 20080201

• Use of recommended medications after myocardial infarction in Austria.

  European journal of epidemiology 20080201

• Aldosterone acts centrally to increase brain renin-angiotensin system activity and oxidative stress in normal rats.

  American journal of physiology. Heart and circulatory physiology 20080201

• Prevention of DNA damage in renal transplantation by losartan and enalapril: the role of renin-angiotensin system polymorphisms.

  Clinical and experimental nephrology 20080201

• Sustained tubulo-interstitial protection in SHRs by transient losartan treatment: an effect of decelerated aging?

  American journal of hypertension 20080201

• Uric acid stimulates vascular smooth muscle cell proliferation and oxidative stress via the vascular renin-angiotensin system.

  Journal of hypertension 20080201

• Combination of exercise and losartan enhances renoprotective and peripheral effects in spontaneously type 2 diabetes mellitus rats with nephropathy.

  Journal of hypertension 20080201

• Switch strategies in the management of hypertension: a cost minimisation analysis of angiotensin receptor blocker based regimen.

  Current medical research and opinion 20080201

• Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment.

  European journal of clinical pharmacology 20080201

• Albuminuria: a great risk marker, but an underestimated target in diabetes.

  Diabetes care 20080201

• Recent advances in understanding Marfan syndrome: should we now treat surgical patients with losartan?

  The Journal of thoracic and cardiovascular surgery 20080201

• Pioglitazone and losartan modify hemodynamic and metabolic parameters and vascular prostanoids in fructose-overloaded rats.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20080201

• Efficacy and safety of long-term losartan therapy demonstrated by a prospective observational study in Japanese patients with hypertension: The Japan Hypertension Evaluation with Angiotensin II Antagonist Losartan Therapy (J-HEALTH) study.

  Hypertension research : official journal of the Japanese Society of Hypertension 20080201

• Angiotensin II regulates cardiac hypertrophy via oxidative stress but not antioxidant enzyme activities in experimental renovascular hypertension.

  Hypertension research : official journal of the Japanese Society of Hypertension 20080201

• Angiotensin II- and glucose-stimulated extracellular matrix production: mediation by the insulin-like growth factor (IGF) axis in a murine mesangial cell line.

  Endocrine 20080201

• Endothelial effects of antihypertensive treatment: focus on irbesartan.

  Vascular health and risk management 20080201

• Angiotensin II receptor blockers and cardiovascular protection: focus on left ventricular hypertrophy regression and atrial fibrillation prevention.

  Vascular health and risk management 20080201

• Application in the STRATHE trial of a score system to compare the efficacy and the tolerability of different therapeutic strategies in the management of hypertension.

  Vascular health and risk management 20080201

• Carvedilol in hypertension treatment.

  Vascular health and risk management 20080201

• Is Peri-Operative Isolated Systolic Hypertension (ISH) a Cardiac Risk Factor?

  Current cardiology reviews 20080201

• Angiotensin II induces proliferation of cultured rat astrocytes through c-Jun N-terminal kinase.

  Brain research bulletin 20080131

• Angiotensin II activates signal transducer and activators of transcription 3 via Rac1 in atrial myocytes and fibroblasts: implication for the therapeutic effect of statin in atrial structural remodeling.

  Circulation 20080122

• [Fewer cases of stroke, atrial fibrillation, diabetes and renal insufficiency. Good treatment of hypertension is more than lowering of blood pressure].

  MMW Fortschritte der Medizin 20080117

• The mechanism of signal transduction during vascular smooth muscle cell proliferation induced by autoantibodies against angiotensin AT1 receptor from hypertension.

  Chinese medical journal 20080105

• Renal effects of urodilatin in healthy subjects are independent of blockade of the cyclooxygenase and angiotensin II receptor.

  Scandinavian journal of clinical and laboratory investigation 20080101

• A renoprotective effect of low dose losartan in patients with type 2 diabetes.

  Diabetes research and clinical practice 20080101

• Differential bonding interactions of inverse agonists of angiotensin II type 1 receptor in stabilizing the inactive state.

  Molecular endocrinology (Baltimore, Md.) 20080101

• Effects of angiotensin II blockade on the development of autoimmune thyroiditis in nonobese diabetic mice.

  Clinical immunology (Orlando, Fla.) 20080101

• The role of local and systemic renin angiotensin system activation in a genetic model of sympathetic hyperactivity-induced heart failure in mice.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080101

• The significance of compliance and persistence in the treatment of diabetes, hypertension and dyslipidaemia: a review.

  International journal of clinical practice 20080101

• Angiotensin II type 1 receptor blockade corrects cutaneous nitric oxide deficit in postural tachycardia syndrome.

  American journal of physiology. Heart and circulatory physiology 20080101

• Regulation of swelling-activated Cl(-) current by angiotensin II signalling and NADPH oxidase in rabbit ventricle.

  Cardiovascular research 20080101

• Renal mitochondrial impairment is attenuated by AT1 blockade in experimental Type I diabetes.

  American journal of physiology. Heart and circulatory physiology 20080101

• Angiotensin II induces vascular endothelial growth factor in pancreatic cancer cells through an angiotensin II type 1 receptor and ERK1/2 signaling.

  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20080101

• The role of angiotensin II receptor-1 blockade in the hypoxic pulmonary vasoconstriction response in newborn piglets.

  Neonatology 20080101

• Angiotensin type 1 receptor antagonist inhibits lipopolysaccharide-induced stimulation of rat microglial cells by suppressing nuclear factor kappaB and activator protein-1 activation.

  The European journal of neuroscience 20080101

• Effects of losartan and enalapril on high-sensitivity C-reactive protein and total antioxidant in renal transplant recipients with Renin-Angiotensin system polymorphisms.

  Transplantation proceedings 20080101

• Accuracy of electrocardiographic criteria for atrial enlargement: validation with cardiovascular magnetic resonance.

  Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20080101

• Rosiglitazone but not losartan prevents Nrf-2 dependent CD36 gene expression up-regulation in an in vivo atherosclerosis model.

  Cardiovascular diabetology 20080101

• Efficacy and tolerability of nebivolol compared with other antihypertensive drugs: a meta-analysis.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20080101

• Effect of angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade on apoptotic changes in contralateral testis following unilateral testicular torsion.

  International urology and nephrology 20080101

• [Losartan for the correction of thrombocyte activity in patients suffering from arterial hypertension with metabolic syndrome].

  Klinicheskaia meditsina 20080101

• Reversal of diuretic-associated impaired glucose tolerance and new-onset diabetes: results of the STAR-LET study.

  Journal of the cardiometabolic syndrome 20080101

• Aliskiren: renin inhibitor for hypertension management.

  Clinical therapeutics 20080101

• Beta-blockers in the treatment of hypertension: latest data and opinions.

  Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20080101

• The MUSCAT study: a Multicenter PROBE Study Comparing the Effects of Angiotensin II Type-1 Receptor Blockers on Self-Monitored Home Blood Pressure in Patients with Morning Hypertension: study design and background characteristics.

  Hypertension research : official journal of the Japanese Society of Hypertension 20080101

• Effect of renin-angiotensin-aldosterone system triple blockade on non-diabetic renal disease: addition of an aldosterone blocker, spironolactone, to combination treatment with an angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker.

  Hypertension research : official journal of the Japanese Society of Hypertension 20080101

• A one-year study of the antiatherosclerotic effect of the angiotensin-II receptor blocker losartan in hypertensive patients. A comparison with angiotension-converting enzyme inhibitors.

  International heart journal 20080101

• Androgens stimulate proximal tubule transport.

  Gender medicine 20080101

• Determinants of steady-state torasemide pharmacokinetics: impact of pharmacogenetic factors, gender and angiotensin II receptor blockers.

  Clinical pharmacokinetics 20080101

• Diabetic retinopathy: an update.

  Indian journal of ophthalmology 20080101

• Development and validation of a risk score for hospitalization for heart failure in patients with Type 2 diabetes mellitus.

  Cardiovascular diabetology 20080101

• Effect of the addition of rosiglitazone to metformin or sulfonylureas versus metformin/sulfonylurea combination therapy on ambulatory blood pressure in people with type 2 diabetes: a randomized controlled trial (the RECORD study).

  Cardiovascular diabetology 20080101

• The effect of bucolome, a CYP2C9 inhibitor, on the pharmacokinetics of losartan.

  Drug metabolism and pharmacokinetics 20080101

• [Are optimal doses of benazepril and losartan to reduce proteinuria more nephroprotective than conventional doses in non-diabetic proteinuric nephropathies?].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20080101

• [spACE, the last frontier? Renin inhibition in hypertension].

  Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20080101

• The effect of voluntary fasting and dehydration on flicker-induced retinal vascular dilation in a healthy individual: a case report.

  Journal of medical case reports 20080101

• [Endothelioprotective properties of L-arginine in a nitric oxide deficiency model].

  Eksperimental'naia i klinicheskaia farmakologiia 20080101

• Prognostic implications of negative dobutamine stress echocardiography in African Americans compared to Caucasians.

  Cardiovascular ultrasound 20080101

• Comprehensive analysis of the mouse renal cortex using two-dimensional HPLC - tandem mass spectrometry.

  Proteome science 20080101

• PPARgamma Agonists: Potential as Therapeutics for Neovascular Retinopathies.

  PPAR research 20080101

• Comparison of angiotensin II type 1 receptor antagonists in the treatment of essential hypertension.

  Drugs 20080101

• Olmesartan medoxomil: a review of its use in the management of hypertension.

  Drugs 20080101

• Distribution of the non-AT1, non-AT2 angiotensin-binding site in the rat brain: preliminary characterization.

  Neuroendocrinology 20080101

• Diabetes mellitus downregulates expression of connexin43 in rat aortic medial smooth muscle cells and can be reversed by simvastatin and losartan therapy.

  Chang Gung medical journal 20080101

• Angiotensin blockade and matrix synthesis by glomerular epithelial cells in high glucose: a further experimental insight into the pathophysiology of diabetic nephropathy.

  La Clinica terapeutica 20080101

• Effect of acute unilateral renal denervation on renal hemodynamics in spontaneously hypertensive rats.

  Autonomic & autacoid pharmacology 20080101

• Effects on plasma noradrenaline may explain some of the improved insulin sensitivity seen by AT-1 receptor blockade.

  Blood pressure 20080101

• New insights in the pathogenesis of aortic aneurysms.

  Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie 20080101

• Reduction in albuminuria translates to reduction in cardiovascular events in hypertensive patients with left ventricular hypertrophy and diabetes.

  Journal of nephrology 20080101

• Reproducibility of 3-dimensional ultrasound readings of volume of carotid atherosclerotic plaque.

  Cardiovascular ultrasound 20080101

• Antihypertensive drug class and impaired fasting glucose: a risk association study among Chinese patients with uncomplicated hypertension.

  BMC clinical pharmacology 20080101

• [Reversible dysgeusia attributed to losartan].

  Medicina 20080101

• The role of nuclear factor-kappaB in the effect of angiotensin II in the paraventricular nucleus in protecting the gastric mucosa from ischemia-reperfusion injury in rats.

  Journal of gastroenterology 20080101

• Bioequivalence study of two different film-coated tablet formulations of losartan-hydrochlorothiazide in healthy volunteers.

  Arzneimittel-Forschung 20080101

• Effort angina in a patient with advanced coronary artery disease. Role played by coronary angiography, Ivus and cardiac CT: case report.

  Cardiovascular ultrasound 20080101

• Central cholinergic signal-mediated neuroendocrine regulation of vasopressin and oxytocin in ovine fetuses.

  BMC developmental biology 20080101

• Modulation of pain perception by ramipril and losartan in human volunteers.

  Indian journal of physiology and pharmacology 20080101

• Relative effects of telmisartan, candesartan and losartan on alleviating arterial stiffness in patients with hypertension complicated by diabetes mellitus: an evaluation using the cardio-ankle vascular index (CAVI).

  The Journal of international medical research 20080101

• Pilot study of an interactive voice response system to improve medication refill compliance.

  BMC medical informatics and decision making 20080101

• Membranous nephropathy in a patient with hereditary angioedema: a case report.

  Journal of medical case reports 20080101

• [Clinical state of a patient with nephrotic proteinuria successfully treated with combined therapy with angiotensin II receptor antagonists and angiotensin II converting enzyme inhibitors and pentoxifylline].

  Przeglad lekarski 20080101

• The prince and the pauper. A tale of anticancer targeted agents.

  Molecular cancer 20080101

• Delay of renal progression in methylmalonic acidemia using angiotensin II inhibition: a case report.

  Journal of nephrology 20080101

• Improved persistence and adherence to diuretic fixed-dose combination therapy compared to diuretic monotherapy.

  BMC family practice 20080101

• Determination of losartan and triamterene in pharmaceutical compounds and urine using cathodic adsorptive stripping voltammetry.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20080101

• Angiotensin receptor blockers are superior to angiotensin-converting enzyme inhibitors in the suppression of hepatic fibrosis in a bile duct-ligated rat model.

  Journal of gastroenterology 20080101

• Left atrioventricular remodeling in the assessment of the left ventricle diastolic function in patients with heart failure: a review of the currently studied echocardiographic variables.

  Cardiovascular ultrasound 20080101

• Redox mechanisms in hepatic chronic wound healing and fibrogenesis.

  Fibrogenesis & tissue repair 20080101

• Clinical review: Drug metabolism and nonrenal clearance in acute kidney injury.

  Critical care (London, England) 20080101

• Cognitive-enhancing effects of angiotensin IV.

  BMC neuroscience 20080101

• Intracardiac thrombus--a rare complication of the steroid resistant nephrotic syndrome.

  Bratislavske lekarske listy 20080101

• Loss of digits after trauma in a patient with systemic lupus erythematosus.

  The western journal of emergency medicine 20080101

• Optimized and validated spectrophotometric methods for the determination of enalapril maleate in commercial dosage forms.

  Analytical chemistry insights 20080101

• Perforating lichenoid reaction to amlodipine.

  Indian journal of dermatology 20080101

• Erythropoietin stimulating agents in the management of anemia of chronic kidney disease.

  Patient preference and adherence 20080101

• Simultaneous Determination of Valsartan and Hydrochlorothiazide in Tablets by RP-HPLC.

  Indian journal of pharmaceutical sciences 20080101

• Validated HPTLC Method for Simultaneous Determination of Quinapril Hydrochloride and Hydrochlorothiazide in a Tablet Dosage Form.

  Indian journal of pharmaceutical sciences 20080101

• Pseudo 'insulin allergy'.

  International journal of diabetes in developing countries 20080101

• Role of beta-blockers in Marfan's syndrome and bicuspid aortic valve: A time for re-appraisal.

  Annals of pediatric cardiology 20080101

• Severe rhabdomyolysis and acute renal failure secondary to the use of simvastatin in undiagnosed hypothyroidism.

  Indian journal of nephrology 20080101

• Subfornical organ mediates pressor effect of angiotensin: Influence of nitric oxide synthase inhibitors, AT(1) and AT(2) angiotensin antagonist's receptors.

  Journal of the American Society of Hypertension : JASH 20080101

• 24-hour powerful blood pressure-lowering: is there a clinical need?

  Journal of the American Society of Hypertension : JASH 20080101

• Slowing the progression of kidney disease in patients with diabetes.

  Journal of the American Society of Hypertension : JASH 20080101

• Is the combination of enalapril and losartan irrational?

  Indian journal of pharmacology 20080101

• A Validated RP-HPLC Method for Simultaneous Estimation of Nebivolol and Hydrochlorothiazide in Tablets.

  Indian journal of pharmaceutical sciences 20080101

• Angiotensin receptor blockers and microalbuminuria in hypertensive patients with early (microalbuminuric) stage diabetic nephropathy.

  Molecular medicine reports 20080101

• Differential response of vascular hepatocyte growth factor concentration and lipid accumulation between telmisartan and losartan in ApoE-deficient mice.

  Molecular medicine reports 20080101

• [Chronic blockade of angiotensin II type 1 receptor cannot completely prevent structural adaptation in vessels of simulated weightless rats].

  Sheng li xue bao : [Acta physiologica Sinica] 20071225

• Angiotensin II type 2 receptors facilitate reinnervation of phenol-lesioned vascular calcitonin gene-related peptide-containing nerves in rat mesenteric arteries.

  Neuroscience 20071212

• [Ca2+]i and PKC-alpha are involved in the inhibitory effects of Ib, a novel nonpeptide AngiotensinII subtype AT1 receptor antagonist, on AngiotensinII-induced vascular contraction in vitro.

  Biochemical and biophysical research communications 20071207

• Chronic kidney disease in children: the global perspective.

  Pediatric nephrology (Berlin, Germany) 20071201

• The angiotensin II receptor 2 is expressed and mediates angiotensin II signaling in lung fibrosis.

  American journal of respiratory cell and molecular biology 20071201

• Mechanisms of progression of chronic kidney disease.

  Pediatric nephrology (Berlin, Germany) 20071201

• ANG II induces c-Jun NH2-terminal kinase activation and proliferation of human mesangial cells via redox-sensitive transactivation of the EGFR.

  American journal of physiology. Renal physiology 20071201

• Maximising antihypertensive effects of angiotensin II receptor blockers with thiazide diuretic combination therapy: focus on irbesartan/hydrochlorothiazide.

  International journal of clinical practice 20071201

• Anabolic steroids induce cardiac renin-angiotensin system and impair the beneficial effects of aerobic training in rats.

  American journal of physiology. Heart and circulatory physiology 20071201

• Angiotensin AT1 receptor antagonists exert anti-inflammatory effects in spontaneously hypertensive rats.

  British journal of pharmacology 20071201

• Microvascular transport model predicts oxygenation changes in the infarcted heart after treatment.

  American journal of physiology. Heart and circulatory physiology 20071201

• Endogenous brain Na pumps, brain ouabain-like substance and the alpha2 isoform in salt-dependent hypertension.

  Pathophysiology : the official journal of the International Society for Pathophysiology 20071201

• Transient prehypertensive treatment in spontaneously hypertensive rats: a comparison of spironolactone and losartan regarding long-term blood pressure and target organ damage.

  Journal of hypertension 20071201

• Validated quantitation of angiotensin II receptor antagonists (ARA-II) in human plasma by liquid-chromatography-tandem mass spectrometry using minimum sample clean-up and investigation of ion suppression.

  Therapeutic drug monitoring 20071201

• Losartan improves heart rate variability and heart rate turbulence in heart failure due to ischemic cardiomyopathy.

  Journal of cardiac failure 20071201

• Plasma MMP-2, MMP-9 and N-BNP in long-term survivors following complicated myocardial infarction: relation to cardiac magnetic resonance imaging measures of left ventricular structure and function.

  Journal of cardiac failure 20071201

• [Effect of losartan on lung fibrosis in neonatal rats with hyperoxia-induced chronic lung disease].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20071201

• Calcitonin gene-related Peptide-mediated depressor effect and inhibiting vascular hypertrophy of rutaecarpine in renovascular hypertensive rats.

  Journal of cardiovascular pharmacology 20071201

• [Effect of losartan on the expressions of TGF-beta1, p-Smad2/3, and Smad7 in the remnant renal tissues of 5/6 nephrectomized rats].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20071201

• Summary of the 2007 European Society of Hypertension (ESH) and European Society of Cardiology (ESC) guidelines for the management of arterial hypertension.

  Vascular health and risk management 20071201

• A review of nateglinide in the management of patients with type 2 diabetes.

  Vascular health and risk management 20071201

• Aliskiren--an orally active renin inhibitor. Review of pharmacology, pharmacodynamics, kinetics, and clinical potential in the treatment of hypertension.

  Vascular health and risk management 20071201

• Endothelial dysfunction in diabetes mellitus.

  Vascular health and risk management 20071201

• Clinical trial update: focus on the ONTARGET study.

  Vascular health and risk management 20071201

• A review of the safety and efficacy of nebivolol in the mildly hypertensive patient.

  Vascular health and risk management 20071201

• Regulation of the renin-angiotensin system in coronary atherosclerosis: a review of the literature.

  Vascular health and risk management 20071201

• The applicability of home blood pressure measurement in clinical practice: a review of literature.

  Vascular health and risk management 20071201

• Reduction of C-reactive protein and the use of anti-hypertensives.

  Vascular health and risk management 20071201

• Rationale for multiple risk intervention: the need to move from theory to practice.

  Vascular health and risk management 20071201

• Assessment of brain AT1-receptor on the nocturnal basal and angiotensin-induced thirst and sodium appetite in ovariectomised rats.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20071201

• Persistent hypertension and progressive renal injury induced by salt overload after short term nitric oxide inhibition.

  Clinics (Sao Paulo, Brazil) 20071201

• Decreased infiltration of macrophages and inhibited activation of nuclear factor-kappa B in blood vessels: a possible mechanism for the anti-atherogenic effects of losartan.

  Acta cardiologica 20071201

• Treatment of non-alcoholic fatty liver disease.

  Therapeutics and clinical risk management 20071201

• [Assessment of therapeutic effect of losartan on diabetes mellitus with gas chromatography-based metabonomics].

  Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20071201

• Effects of acute stress on the day of proestrus on sexual behavior and ovulation in female rats: participation of the angiotensinergic system.

  Physiology & behavior 20071123

• Angiotensin II protects against alpha-synuclein toxicity and reduces protein aggregation in vitro.

  Biochemical and biophysical research communications 20071123

• Selective angiotensin II AT(2) receptor agonists devoid of the imidazole ring system.

  Bioorganic & medicinal chemistry 20071115

• Effect of losartan in treatment of exercise-induced myocardial ischemia.

  The American journal of cardiology 20071115

• Development of the 'Inje cocktail' for high-throughput evaluation of five human cytochrome P450 isoforms in vivo.

  Clinical pharmacology and therapeutics 20071101

• Angiotensin II-induced mitogen-activated protein kinase phosphatase-1 expression in bovine adrenal glomerulosa cells: implications in mineralocorticoid biosynthesis.

  Endocrinology 20071101

• CXCR2 blockade impairs angiotensin II-induced CC chemokine synthesis and mononuclear leukocyte infiltration.

  Arteriosclerosis, thrombosis, and vascular biology 20071101

• Roles of vasoconstrictor prostaglandins, COX-1 and -2, and AT1, AT2, and TP receptors in a rat model of early 2K,1C hypertension.

  American journal of physiology. Heart and circulatory physiology 20071101

• Angiotension II receptor 1 blocker modifies the expression of apoptosis-related proteins and transforming growth factor-beta1 in prostate tissue of spontaneously hypertensive rats.

  BJU international 20071101

• Mitochondrial reactive oxygen species activate the slow force response to stretch in feline myocardium.

  The Journal of physiology 20071101

• Failure of antioxidants to protect against angiotensin II-induced aortic rupture in aged apolipoprotein(E)-deficient mice.

  British journal of pharmacology 20071101

• Association of increased plasma cardiotrophin-1 with inappropriate left ventricular mass in essential hypertension.

  Hypertension (Dallas, Tex. : 1979) 20071101

• Vascular smooth muscle G(q) signaling is involved in high blood pressure in both induced renal and genetic vascular smooth muscle-derived models of hypertension.

  American journal of physiology. Heart and circulatory physiology 20071101

• Angiotensin II receptors subtypes mediate diverse gene expression profile in adult hypertrophic cardiomyocytes.

  Clinical and experimental pharmacology & physiology 20071101

• Left ventricular hypertrophy reversal and prevention of diabetes: two birds with one stone?

  Hypertension (Dallas, Tex. : 1979) 20071101

• Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway.

  Hypertension (Dallas, Tex. : 1979) 20071101

• In-treatment resolution or absence of electrocardiographic left ventricular hypertrophy is associated with decreased incidence of new-onset diabetes mellitus in hypertensive patients: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) Study.

  Hypertension (Dallas, Tex. : 1979) 20071101

• Improved insulin sensitivity by the angiotensin II-receptor blocker losartan is not explained by adipokines, inflammatory markers, or whole blood viscosity.

  Metabolism: clinical and experimental 20071101

• The effect of angiotensin II and IV on ERK1/2 and CREB signalling in cultured rat astroglial cells.

  Naunyn-Schmiedeberg's archives of pharmacology 20071101

• Nitric oxide and angiotensin II receptors mediate the pressor effect of angiotensin II: a study in conscious and zoletil-anesthetized rats.

  Anesthesia and analgesia 20071101

• The role of angiotensin II in the early stages of bovine ovulation.

  Reproduction (Cambridge, England) 20071101

• Sarcoidosis affecting the periodontium: a long-term follow-up case.

  Journal of periodontology 20071101

• Pathophysiology of target-organ disease: does angiotensin II remain the key?

  Journal of clinical hypertension (Greenwich, Conn.) 20071101

• Conceptual basis and methodology of the SOPHIA study.

  Pharmacogenomics 20071101

• A combination of a PPAR-gamma agonist and an angiotensin II receptor blocker attenuates proinflammatory signaling and stimulates expression of Smad7 in human peritoneal mesothelial cells.

  Clinical nephrology 20071101

• Anti-angiotensin therapy: new perspectives.

  Cardiology clinics 20071101

• [The influence of angiotensin II receptor blockade on the expressions of Col I and TIMP-1 mRNA in cardiac fibroblast of adult rat].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20071101

• A new therapeutic strategy for hypertrophic nonobstructive cardiomyopathy in humans. A randomized and prospective study with an Angiotensin II receptor blocker.

  International heart journal 20071101

• The renin-Angiotensin system: a potential modulator of endothelial progenitor cells.

  Hypertension research : official journal of the Japanese Society of Hypertension 20071101

• Losartan improves the impaired function of endothelial progenitor cells in hypertension via an antioxidant effect.

  Hypertension research : official journal of the Japanese Society of Hypertension 20071101

• Effect of L-5-Hydroxytryptophan on drinking behavior in Coturnix japonica (Temminck and Schlegel, 1849) (Galliformes: Aves): involvement of renin-angiotensin system.

  Brazilian journal of biology = Revista brasleira de biologia 20071101

• Interaction of signal transduction between angiotensin AT1 and AT2 receptor subtypes in rat senescent heart.

  Chinese medical journal 20071020

• Angiotensin II increases evoked release at the frog neuromuscular junction through a receptor sensitive to A779.

  Brain research 20071017

• Involvement of an enterocyte renin-angiotensin system in the local control of SGLT1-dependent glucose uptake across the rat small intestinal brush border membrane.

  The Journal of physiology 20071015

• Beneficial effects of losartan on vascular injury induced by advanced glycosylation end products and their receptors in spontaneous hypertension rats.

  Molecular and cellular biochemistry 20071001

• Vasopressin and angiotensin receptors of the medial septal area of the brain in the control of thirst and salt appetite induced by vasopressin in water-deprived and sodium-depleted rats.

  Pharmacology, biochemistry, and behavior 20071001

• Angiotensin II type 1 receptor-dependent nuclear factor-kappaB activation-mediated proinflammatory actions in a rat model of obstructive acute pancreatitis.

  The Journal of pharmacology and experimental therapeutics 20071001

• Exercise training restores aerobic capacity and energy transfer systems in heart failure treated with losartan.

  Cardiovascular research 20071001

• Tissue kallikrein is involved in the cardioprotective effect of AT1-receptor blockade in acute myocardial ischemia.

  The Journal of pharmacology and experimental therapeutics 20071001

• Intra-renal angiotensin II/AT1 receptor, oxidative stress, inflammation, and progressive injury in renal mass reduction.

  The Journal of pharmacology and experimental therapeutics 20071001

• Angiotensin II attenuates myocardial interstitial acetylcholine release in response to vagal stimulation.

  American journal of physiology. Heart and circulatory physiology 20071001

• Losartan and its interaction with copper(II): biological effects.

  Bioorganic & medicinal chemistry 20071001

• Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis.

  American journal of physiology. Regulatory, integrative and comparative physiology 20071001

• Effect of angiotensin AT1 receptor antagonist on D-galactosamine-induced acute liver injury.

  Clinical and experimental pharmacology & physiology 20071001

• Sympathetic hyperactivity and cardiac dysfunction post-MI: different impact of specific CNS versus general AT1 receptor blockade.

  Journal of molecular and cellular cardiology 20071001

• Reactive oxygen species in the paraventricular nucleus mediate the cardiac sympathetic afferent reflex in chronic heart failure rats.

  European journal of heart failure 20071001

• The renin-angiotensin and 'drinking' behavior.

  Journal of molecular medicine (Berlin, Germany) 20071001

• The effect of baseline physical activity on cardiovascular outcomes and new-onset diabetes in patients treated for hypertension and left ventricular hypertrophy: the LIFE study.

  Journal of internal medicine 20071001

• Rationale and design of a randomized clinical trial of beta-blocker therapy (atenolol) versus angiotensin II receptor blocker therapy (losartan) in individuals with Marfan syndrome.

  American heart journal 20071001

• Effect of acute hyperinsulinaemia with and without angiotensin II type 1 receptor blockade on resistin and adiponectin concentrations and expressions in healthy subjects.

  European journal of endocrinology 20071001

• Captopril inhibits capillary degeneration in the early stages of diabetic retinopathy.

  Current eye research 20071001

• The signalling of AT2 and the influence on the collagen metabolism of AT2 receptor in adult rat cardiac fibroblasts.

  Acta cardiologica 20071001

• Transient left ventricular dysfunction due to stress-induced cardiomyopathy.

  Arquivos brasileiros de cardiologia 20071001

• Angiotensin-(1-7) inhibits in vitro endothelial cell tube formation in human umbilical vein endothelial cells through the AT(1-7) receptor.

  Endocrine 20071001

• Comparison of home and office blood pressure in hypertensive patients treated with zofenopril or losartan.

  Blood pressure. Supplement 20071001

• Renoprotective effect of the addition of losartan to ongoing treatment with an angiotensin converting enzyme inhibitor in type-2 diabetic patients with nephropathy.

  Hypertension research : official journal of the Japanese Society of Hypertension 20071001

• Dilation of renal artery stenosis after administration of losartan.

  Hypertension research : official journal of the Japanese Society of Hypertension 20071001

• Calcium channel blockers, angiotensin receptor blockers, and angiotensin-converting enzyme inhibitors: effectiveness in combination with diuretics or beta-blockers for treating hypertension.

  Vascular health and risk management 20071001

• Nebivolol in the treatment of chronic heart failure.

  Vascular health and risk management 20071001

• Macro- and micronutrients in patients with congestive heart failure, particularly African-Americans.

  Vascular health and risk management 20071001

• [Association between murine double minute 2 expression and AngII and ceramide induced endothelial cells apoptosis].

  Zhonghua xin xue guan bing za zhi 20071001

• Studies point way to new therapeutic prospects for muscular dystrophy.

  JAMA 20070926

• Intravenous hypertonic NaCl acts via cerebral sodium-sensitive and angiotensinergic mechanisms to improve cardiac function in haemorrhaged conscious sheep.

  The Journal of physiology 20070915

• [Fixed-combination of losartan/hydrochlorothiazide 100 mg/25 mg. Tolerability and efficacy on blood pressure measured in the practice and for 24 hours].

  MMW Fortschritte der Medizin 20070913

• [Fixed-combination of losartan/hydrochlorothiazide 100 mg/25 mg. Tolerability and efficacy on blood pressure measured in the practice and for 24 hours].

  MMW Fortschritte der Medizin 20070906

• Regression of electrocardiographic left ventricular hypertrophy is associated with less hospitalization for heart failure in hypertensive patients.

  Annals of internal medicine 20070904

• Angiotensin II type 1-receptor antagonism prevents type IIA secretory phospholipase A2-dependent lipid peroxidation.

  Atherosclerosis 20070901

• Angiotensin receptor type 1 blockade in astroglia decreases hypoxia-induced cell damage and TNF alpha release.

  Neurochemical research 20070901

• Bosentan and losartan ameliorate acute renal failure associated with mild but not strong NO blockade.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070901

• Protective effect of long-term angiotensin II inhibition.

  American journal of physiology. Heart and circulatory physiology 20070901

• Increased epithelial cell proliferation in the ileal pouch mucosa of patients with familial adenomatous polyposis.

  Virchows Archiv : an international journal of pathology 20070901

• AT1 receptor ligands: virtual-screening-based design with TOPP descriptors, synthesis, and biological evaluation of pyrrolidine derivatives.

  ChemMedChem 20070901

• The effects of simultaneous administration of dietary conjugated linoleic acid and telmisartan on cardiovascular risks in rats.

  Lipids 20070901

• Hepatic conversion of angiotensin I and the portal hypertensive response to angiotensin II in normal and regenerating liver.

  Journal of gastroenterology and hepatology 20070901

• Unrecognized glycometabolic disturbance as measured by hemoglobin A1c is associated with a poor outcome after acute myocardial infarction.

  American heart journal 20070901

• Effect of hemoglobin levels on cardiovascular outcomes in patients with isolated systolic hypertension and left ventricular hypertrophy (from the LIFE study).

  The American journal of cardiology 20070901

• Functional and morphological improvement in erectile tissue of hypertensive rats by long-term combined therapy with phosphodiesterase type 5 inhibitor and losartan.

  The journal of sexual medicine 20070901

• Intrahippocampal microinjection of an exquisitely low dose of ouabain mimics NaCl loading and stimulates a bufadienolide Na/K-ATPase inhibitor.

  Journal of hypertension 20070901

• [Role of AT2 receptors on angiotensin II-induced tumor necrosis factor alpha and interleukin 1 beta secretion in adult rat cardiac fibroblasts].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070901

• Angiotensin II receptor blockade blocker pre-treatment largely prevents injury from gradual renal ablation in rats.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20070901

• [Effects of losartan on expressions of plasminogen activator and plasminogen activator inhibitor-1 of rat proximal tubular epithelial cells cultured with high glucose].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070901

• [Comparative characteristic of angiotensin-converting enzyme inhibitor--captopril and the angiotensin II receptor blokers--losartan action on the oxidative metabolism in experimental hyperlipidemia in rabbits].

  Georgian medical news 20070901

• Design and baseline characteristics of an observational study in Japanese patients with hypertension: Japan Hypertension Evaluation with Angiotensin II Antagonist Losartan Therapy (J-HEALTH).

  Hypertension research : official journal of the Japanese Society of Hypertension 20070901

• Effectiveness of add-on low-dose diuretics in combination therapy for hypertension: losartan/hydrochlorothiazide vs. candesartan/amlodipine.

  Hypertension research : official journal of the Japanese Society of Hypertension 20070901

• Prehypertensive renin-angiotensin-aldosterone system blockade in spontaneously hypertensive rats ameliorates the loss of long-term vascular function.

  Hypertension research : official journal of the Japanese Society of Hypertension 20070901

• [Chronic effects on the prevention of atrial fibrillation recurrence in patients with lone paroxysmal atrial fibrillation treated with amiodarone, segmental pulmonary vein ablation, or amiodarone plus losartan: a prospective cohort study].

  Zhonghua xin xue guan bing za zhi 20070901

• [Effects of adrenomedullin on angiotensin II-induced collagen synthesis in vascular adventitial fibroblasts].

  Zhonghua xin xue guan bing za zhi 20070901

• Pulmonary hypertension and chronic cor pulmonale in COPD.

  International journal of chronic obstructive pulmonary disease 20070901

• [Involvement of the foot in metabolic diseases].

  Praxis 20070822

• Interaction of AT1 receptors and V1a receptors-mediated effects in the central cardiovascular control during the post-infarct state.

  Regulatory peptides 20070816

• Regression of electrocardiographic left ventricular hypertrophy during antihypertensive therapy and reduction in sudden cardiac death: the LIFE Study.

  Circulation 20070814

• An update on non-peptide angiotensin receptor antagonists and related RAAS modulators.

  Life sciences 20070802

• Angiotensin II-induced C-reactive protein generation: inflammatory role of vascular smooth muscle cells in atherosclerosis.

  Atherosclerosis 20070801

• The up-regulation of angiotensin II receptor type 1 and connective tissue growth factor are involved in high-glucose-induced fibronectin production by cultured human dermal fibroblasts.

  Journal of dermatological science 20070801

• Angiotensin II-induced sudden arrhythmic death and electrical remodeling.

  American journal of physiology. Heart and circulatory physiology 20070801

• Enhanced activity of ventricular Na+-HCO3- cotransport in pressure overload hypertrophy.

  American journal of physiology. Heart and circulatory physiology 20070801

• Clusters of metabolic risk factors predict cardiovascular events in hypertension with target-organ damage: the LIFE study.

  Journal of human hypertension 20070801

• Angiotensin-(1 7) stimulates the phosphorylation of JAK2, IRS-1 and Akt in rat heart in vivo: role of the AT1 and Mas receptors.

  American journal of physiology. Heart and circulatory physiology 20070801

• Angiotensin II protects fibroblast-like synoviocytes from apoptosis via the AT1-NF-kappaB pathway.

  Rheumatology (Oxford, England) 20070801

• Genetic deletion of AT1a receptors attenuates intracellular accumulation of ANG II in the kidney of AT1a receptor-deficient mice.

  American journal of physiology. Renal physiology 20070801

• Renin gene polymorphisms and haplotypes, blood pressure, and responses to renin-angiotensin system inhibition.

  Hypertension (Dallas, Tex. : 1979) 20070801

• Angiotensin inhibition decreases progression of advanced atherosclerosis and stabilizes established atherosclerotic plaques.

  Journal of the American Society of Nephrology : JASN 20070801

• Losartan decreases vasopressin-mediated cAMP accumulation in the thick ascending limb of the loop of Henle in rats with congestive heart failure.

  Acta physiologica (Oxford, England) 20070801

• ACE inhibition and endothelial function: main findings of PERFECT, a sub-study of the EUROPA trial.

  Cardiovascular drugs and therapy 20070801

• How evidence-based are the recommendations in evidence-based guidelines?

  PLoS medicine 20070801

• Angiotensin AT1 receptor blockers suppress ischemia/reperfusion-induced gastric injury in rats.

  Inflammopharmacology 20070801

• Impairment of endothelium-dependent relaxation of rat aortas by homocysteine thiolactone and attenuation by captopril.

  Journal of cardiovascular pharmacology 20070801

• Angiotensin II is a critical mediator of prazosin-induced angiogenesis in skeletal muscle.

  Microcirculation (New York, N.Y. : 1994) 20070801

• Inhibitory effects of angiotensin receptor blockers on CYP2C9 activity in human liver microsomes.

  Drug metabolism and pharmacokinetics 20070801

• Reduction of asymmetric dimethylarginine involved in the cardioprotective effect of losartan in spontaneously hypertensive rats.

  Canadian journal of physiology and pharmacology 20070801

• Antihypertensive efficacy and safety of fixed-dose combination therapy with losartan plus hydrochlorothiazide in Japanese patients with essential hypertension.

  Hypertension research : official journal of the Japanese Society of Hypertension 20070801

• Effect of compound EXP-2528 on angiotensin II-induced E-selectin and VCAM-1 expression in rat brain microvascular endothelial cells in vitro.

  Yao xue xue bao = Acta pharmaceutica Sinica 20070801

• Ambulatory blood pressure in hypertensive patients with left ventricular hypertrophy: efficacy of first-line combination perindopril/indapamide therapy.

  Vascular health and risk management 20070801

• Arterial stiffness and pharmacological interventions--the TRanscend arterial stiffNess Substudy (TRANS study).

  Vascular health and risk management 20070801

• Valsartan in the treatment of heart failure or left ventricular dysfunction after myocardial infarction.

  Vascular health and risk management 20070801

• Managing hypertension in diabetic patients--focus on trandolapril/verapamil combination.

  Vascular health and risk management 20070801

• The burden of type 2 diabetes: strategies to prevent or delay onset.

  Vascular health and risk management 20070801

• Common pathways of hypercholesterolemia and hypertension leading to atherothrombosis: the need for a global approach in the management of cardiovascular risk factors.

  Vascular health and risk management 20070801

• 17beta-estradiol inhibits angiotensin II-induced collagen synthesis of cultured rat cardiac fibroblasts via modulating angiotensin II receptors.

  European journal of pharmacology 20070719

• The spironolactone, amiloride, losartan, and thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio.

  Circulation 20070717

• Angiotensin type-1 receptor blockade with losartan increases insulin sensitivity and improves glucose homeostasis in subjects with type 2 diabetes and nephropathy.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070701

• Selective knockdown of AT1 receptors by RNA interference inhibits Val5-ANG II endocytosis and NHE-3 expression in immortalized rabbit proximal tubule cells.

  American journal of physiology. Cell physiology 20070701

• Modulation of angiotensin II and norepinephrine-induced plasminogen activator inhibitor-1 expression by AT1a receptor deficiency.

  Kidney international 20070701

• Hepatic morphological alterations, glycogen content and cytochrome P450 activities in rats treated chronically with N(omega)-nitro-L-arginine methyl ester (L-NAME).

  Cell and tissue research 20070701

• Angiotensin AT1-receptor inhibition exacerbates renal injury resulting from partial unilateral ureteral obstruction in the neonatal rat.

  American journal of physiology. Renal physiology 20070701

• 17beta-estradiol deficiency reduces potassium excretion in an angiotensin type 1 receptor-dependent manner.

  American journal of physiology. Heart and circulatory physiology 20070701

• Prevention of hypertension abrogates early inflammatory events in the retina of diabetic hypertensive rats.

  Experimental eye research 20070701

• Modulation of a delayed-rectifier K+ current by angiotensin II in rat sympathetic neurons.

  Journal of neurophysiology 20070701

• Angiotensin II Type 1 receptor antagonism mediates uncoupling protein 2-driven oxidative stress and ameliorates pancreatic islet beta-cell function in young Type 2 diabetic mice.

  Antioxidants & redox signaling 20070701

• Angiotensin-(1-7) blocks the angiotensin II-stimulated superoxide production.

  Pharmacological research 20070701

• Dose and time-dependent apoptotic effects by angiotensin II infusion on left ventricular cardiomyocytes.

  Journal of hypertension 20070701

• Chronic salt loading and cardiovascular-associated changes in experimental diabetes in rats.

  Clinical and experimental pharmacology & physiology 20070701

• Electrocardiographic and echocardiographic detection of myocardial infarction in patients with left-ventricular hypertrophy. The LIFE Study.

  American journal of hypertension 20070701

• Angiotensin receptor antagonist vs. angiotensin-converting enzyme inhibitor in Asian subjects with type 2 diabetes and albuminuria - a randomized crossover study.

  Diabetes, obesity & metabolism 20070701

• Sudden cardiac standstill during skin flap elevation in a patient undergoing craniotomy.

  Journal of neurosurgical anesthesiology 20070701

• New treatments for gout.

  Joint, bone, spine : revue du rhumatisme 20070701

• Chimney stove intervention to reduce long-term wood smoke exposure lowers blood pressure among Guatemalan women.

  Environmental health perspectives 20070701

• The effect of diet on simvastatin and losartan enhancement of endothelial function.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20070701

• [Peroxisome proliferator-activated receptor activator troglitazone inhibits angiotensin II-stimulated secretion of vasoactive factors by endothelial cells].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070701

• Beneficial effects of the combination of nifedipine and losartan in hypertensive Dahl salt-sensitive rats.

  Journal of cardiovascular pharmacology 20070701

• Comparative interaction of few antihypertensive drugs with cyclosporine-A in rats.

  Indian journal of experimental biology 20070701

• Losartan preserves integrity of cardiac gap junctions and PGC-1 alpha gene expression and prevents cellular apoptosis in remote area of left ventricular myocardium following acute myocardial infarction.

  International heart journal 20070701

• A novel phosphoinositide 3-kinase-dependent pathway for angiotensin II/AT-1 receptor-mediated induction of collagen synthesis in MES-13 mesangial cells.

  The Journal of biological chemistry 20070629

• Angiotensin-(3-7) pressor effect at the rostral ventrolateral medulla.

  Regulatory peptides 20070607

• Angiotensin II increases expression and secretion of cathepsin F in cultured human monocyte-derived macrophages: an angiotensin II type 2 receptor-mediated effect.

  Atherosclerosis 20070601

• Role of the renin-angiotensin system in ventilator-induced lung injury: an in vivo study in a rat model.

  Thorax 20070601

• Losartan prevents stretch-induced electrical remodeling in cultured atrial neonatal myocytes.

  American journal of physiology. Heart and circulatory physiology 20070601

• Angiotensin II type 1 and bradykinin B2 receptors expressed in early stage epithelial cells derived from human embryonic stem cells.

  Journal of cellular physiology 20070601

• Losartan-hydrochlorothiazide association promotes lasting blood pressure normalization and completely arrests long-term renal injury in the 5/6 ablation model.

  American journal of physiology. Renal physiology 20070601

• Central AT(1) receptor blockade increases metabolic cost during exercise reducing mechanical efficiency and running performance in rats.

  Neuropeptides 20070601

• An angiotensin II receptor antagonist suppresses running-enhanced hippocampal neurogenesis in rat.

  Neuroscience research 20070601

• Pulsology reloaded: commentary on similar effects of treatment on central and brachial blood pressure in older hypertensive subjects.

  Hypertension (Dallas, Tex. : 1979) 20070601

• Renoprotection of Optimal Antiproteinuric Doses (ROAD) Study: a randomized controlled study of benazepril and losartan in chronic renal insufficiency.

  Journal of the American Society of Nephrology : JASN 20070601

• Inhibitory effect of valproic acid on cytochrome P450 2C9 activity in epilepsy patients.

  Basic & clinical pharmacology & toxicology 20070601

• Epigallocatechin-3 gallate prevents cardiac hypertrophy induced by pressure overload in rats.

  Journal of veterinary science 20070601

• Effect of losartan on early liver fibrosis development in a rat model of nonalcoholic steatohepatitis.

  Journal of gastroenterology and hepatology 20070601

• Mesangial proliferative glomerulonephritis with aldosterone-producing adenoma.

  Clinical and experimental nephrology 20070601

• [Role of the renin-angiotensin system on the sympathetic response induced by the cold pressor test in humans].

  Investigacion clinica 20070601

• [Effect of losartan on portal hypertensive gastropathy in rats].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20070601

• Cross-talk related to insulin and angiotensin II binding on myocardial remodelling in diabetic rat hearts.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20070601

• Beneficial versus harmful effects of Angiotensin (1-7) on impulse propagation and cardiac arrhythmias in the failing heart.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20070601

• Low-dose renin inhibitor and low-dose AT(1)-receptor blocker therapy ameliorate target-organ damage in rats harbouring human renin and angiotensinogen genes.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20070601

• Is the fixed-dose combination of telmisartan and hydrochlorothiazide a good approach to treat hypertension?

  Vascular health and risk management 20070601

• Fixed combination of losartan and hydrochlorothiazide and reduction of risk of stroke.

  Vascular health and risk management 20070601

• Multivariate risk assessment and risk score cards in hypertension.

  Vascular health and risk management 20070601

• Use of losartan in reducing microalbuminuria in normotensive patients with type-2 diabetes mellitus.

  Nepal Medical College journal : NMCJ 20070601

• Delayed effects of hypotensive drugs on structural characteristics of the renal glomerular system in hypertensive NISAG rats.

  Bulletin of experimental biology and medicine 20070601

• [ARB: characteristics, mechanisms of action, pharmacokinetics, indication, contraindication, clinical data, and side effects].

  Nihon rinsho. Japanese journal of clinical medicine 20070528

• [Pharmocological therapeutics for chronic heart failure--how to use ARB (angiotensin receptor blocker].

  Nihon rinsho. Japanese journal of clinical medicine 20070528

• Angiotensin II increases expression of alpha1C subunit of L-type calcium channel through a reactive oxygen species and cAMP response element-binding protein-dependent pathway in HL-1 myocytes.

  Circulation research 20070525

• Synthesis and biological activity of 2-alkylbenzimidazoles bearing a N-phenylpyrrole moiety as novel angiotensin II AT1 receptor antagonists.

  Bioorganic & medicinal chemistry letters 20070515

• Cardiovascular response to renin substrate microinjection into the central nucleus of the amygdala of rats.

  Neuroreport 20070507

• Phosphoinositide hydrolysis increase by angiotensin-(1--7) in neonatal rat brain.

  Regulatory peptides 20070503

• Simultaneous determination of 6 beta-blockers, 3 calcium-channel antagonists, 4 angiotensin-II antagonists and 1 antiarrhythmic drug in post-mortem whole blood by automated solid phase extraction and liquid chromatography mass spectrometry. Method development and robustness testing by experimental design.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501

• Angiotensin II increases adipose angiotensinogen expression.

  American journal of physiology. Endocrinology and metabolism 20070501

• Angiotensin II type 1 receptor signaling contributes to platelet-leukocyte-endothelial cell interactions in the cerebral microvasculature.

  American journal of physiology. Heart and circulatory physiology 20070501

• Investigation of the mechanisms by which chronic infusion of an acutely subpressor dose of angiotensin II induces hypertension.

  American journal of physiology. Regulatory, integrative and comparative physiology 20070501

• The role of the renin-angiotensin system and oxidative stress in spontaneously hypertensive rat mesenteric collateral growth impairment.

  American journal of physiology. Heart and circulatory physiology 20070501

• Angiotensin blockade as sole treatment for proteinuric kidney disease in children.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501

• Palatability of angiotensin II antagonists among nephropathic children.

  British journal of clinical pharmacology 20070501

• Induction of monocyte chemoattractant protein-1 expression by angiotensin II in the pancreatic islets and beta-cells.

  Endocrinology 20070501

• Angiotensin II induces angiogenesis in the hypoxic adult mouse heart in vitro through an AT2-B2 receptor pathway.

  Hypertension (Dallas, Tex. : 1979) 20070501

• Inhibition of the renin-angiotensin system abolishes the proatherogenic effect of uremia in apolipoprotein E-deficient mice.

  Arteriosclerosis, thrombosis, and vascular biology 20070501

• EXP3179 inhibits collagen-dependent platelet activation via glycoprotein receptor-VI independent of AT1-receptor antagonism: potential impact on atherothrombosis.

  Arteriosclerosis, thrombosis, and vascular biology 20070501

• Cerebral hemodynamics after short- and long-term reduction in blood pressure in mild and moderate hypertension.

  Hypertension (Dallas, Tex. : 1979) 20070501

• Effects of poststroke losartan versus captopril treatment on myogenic and endothelial function in the cerebrovasculature of SHRsp.

  Stroke 20070501

• Urinary angiotensinogen as a marker of intrarenal angiotensin II activity associated with deterioration of renal function in patients with chronic kidney disease.

  Journal of the American Society of Nephrology : JASN 20070501

• Albuminuria is a target for renoprotective therapy independent from blood pressure in patients with type 2 diabetic nephropathy: post hoc analysis from the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial.

  Journal of the American Society of Nephrology : JASN 20070501

• Enhanced angiotensin II production by renal mesangium is responsible for apoptosis/proliferation of endothelial and epithelial cells in a model of malignant hypertension.

  Journal of hypertension 20070501

• Electrocardiographic characteristics and metabolic risk factors associated with inappropriately high left ventricular mass in patients with electrocardiographic left ventricular hypertrophy: the LIFE Study.

  Journal of hypertension 20070501

• Mineralocorticoid modulation of central angiotensin-induced neuronal activity, water intake and sodium appetite.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20070501

• Antihypertensives as novel antineoplastics: angiotensin-I-converting enzyme inhibitors and angiotensin II type 1 receptor blockers in pancreatic ductal adenocarcinoma.

  Journal of the American College of Surgeons 20070501

• Prednisolone co-administered with losartan confers renoprotection in patients with IgA nephropathy.

  Renal failure 20070501

• Renin-angiotensin system polymorphisms and hemoglobin level in renal allografts: a comparative study between losartan and enalapril.

  Transplantation proceedings 20070501

• An economic assessment of losartan-based versus atenolol-based therapy in patients with hypertension and left-ventricular hypertrophy: results from the Losartan Intervention For Endpoint reduction (LIFE) study adapted to The Netherlands.

  Clinical therapeutics 20070501

• Induction of PPAR gamma mRNA and protein expression by rosiglitazone in chronic cyclosporine nephropathy in the rat.

  Yonsei medical journal 20070430

• [J-ELAN study (effect of losartan and amlodipine on left ventricular diastolic function in patients with mild-to-moderate hypertension)].

  Nihon rinsho. Japanese journal of clinical medicine 20070428

• [Relation between changes in retinal microcirculation and other organ damage in hypertension and regression with antihypertensive treatment].

  Medicina clinica 20070428

• Identification of a novel non-AT1, non-AT2 angiotensin binding site in the rat brain.

  Brain research 20070427

• Influence of angiotensin II on expression of toll-like receptor 2 and maturation of dendritic cells in chronic cyclosporine nephropathy.

  Transplantation 20070415

• Intracerebroventricular injection of losartan inhibits angiotensin II-sensitive neurons via GABA inputs in the anterior hypothalamic area of rats.

  Neuroscience letters 20070412

• Local production of angiotensin II in the subfornical organ causes elevated drinking.

  The Journal of clinical investigation 20070402

• Mitigation of radiation-induced optic neuropathy in rats by ACE inhibitor ramipril: importance of ramipril dose and treatment time.

  Journal of neuro-oncology 20070401

• Release modulating hydrophilic matrix systems of losartan potassium: optimization of formulation using statistical experimental design.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070401

• Liquid chromatographic determination of irbesartan in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070401

• Enhanced AT1 receptor-mediated vasocontractile response to ANG II in endothelium-denuded aorta of obese Zucker rats.

  American journal of physiology. Heart and circulatory physiology 20070401

• Angiotensin type 1 (AT1) and type 2 (AT2) receptors mediate the increase in TGF-beta1 in thyroid hormone-induced cardiac hypertrophy.

  Pflugers Archiv : European journal of physiology 20070401

• Angiotensin II induces endothelial xanthine oxidase activation: role for endothelial dysfunction in patients with coronary disease.

  Arteriosclerosis, thrombosis, and vascular biology 20070401

• Losartan reduces the increased participation of cyclooxygenase-2-derived products in vascular responses of hypertensive rats.

  The Journal of pharmacology and experimental therapeutics 20070401

• Effect of dual blockade of renin-angiotensin system on TGFbeta1 and left ventricular structure and function in hypertensive patients.

  Journal of human hypertension 20070401

• Effect of losartan, compared with atenolol, on endothelial function and oxidative stress in patients with type 2 diabetes and hypertension.

  Journal of hypertension 20070401

• Angiotensin II receptor blockers for the treatment of heart failure: a class effect?

  Pharmacotherapy 20070401

• Blood pressure-lowering efficacy of olmesartan relative to other angiotensin II receptor antagonists: an overview of randomized controlled studies.

  Fundamental & clinical pharmacology 20070401

• Expedited blood pressure control with initial angiotensin II antagonist/diuretic therapy compared with stepped-care therapy in patients with ambulatory systolic hypertension.

  The Canadian journal of cardiology 20070401

• [Blood pressure reduction with additional benefits].

  Medizinische Monatsschrift fur Pharmazeuten 20070401

• The effects of captopril and losartan on erythrocyte membrane Na+/K(+)-ATPase activity in experimental diabetes mellitus.

  Journal of enzyme inhibition and medicinal chemistry 20070401

• Heart failure treatment profile at the beta blockers era.

  Arquivos brasileiros de cardiologia 20070401

• The availability and affordability of selected essential medicines for chronic diseases in six low- and middle-income countries.

  Bulletin of the World Health Organization 20070401

• [Losartan inhibited angiotensin induced human lung fibroblast transformation and collagen synthesis].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20070401

• [New therapeutic targets for ACE inhibitors and angiotensin receptor blockers].

  Polskie Archiwum Medycyny Wewnetrznej 20070401

• Comparison of the cardioprotective effects of cardos and losartan in rats with experimental chronic cardiac insufficiency.

  Bulletin of experimental biology and medicine 20070401

• [Losartan-induced Stevens-Johnson syndrome in a geriatric patient].

  Ugeskrift for laeger 20070326

• Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channels.

  Neuroscience letters 20070319

• [Therapeutic management of acral manifestations of systemic sclerosis].

  Medizinische Klinik (Munich, Germany : 1983) 20070315

• Angiotensin II inhibits the ROMK-like small conductance K channel in renal cortical collecting duct during dietary potassium restriction.

  The Journal of biological chemistry 20070302

• Alloxan-induced diabetes reduces sarcolemmal Na+-K+ pump function in rabbit ventricular myocytes.

  American journal of physiology. Cell physiology 20070301

• AT1 receptors in the nucleus tractus solitarii mediate the interaction between the baroreflex and the cardiac sympathetic afferent reflex in anesthetized rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20070301

• Agonistic angiotensin II type 1 receptor autoantibodies in postpartum women with a history of preeclampsia.

  Hypertension (Dallas, Tex. : 1979) 20070301

• Exercise training prevents arterial baroreflex dysfunction in rats treated with central angiotensin II.

  Hypertension (Dallas, Tex. : 1979) 20070301

• Sympathetic hyperactivity in hypertensive chronic kidney disease patients is reduced during standard treatment.

  Hypertension (Dallas, Tex. : 1979) 20070301

• Angiotensin II increases tissue-specific inhibitor of metalloproteinase-2 expression in rat aortic smooth muscle cells in vivo: evidence of a pressure-independent effect.

  Clinical and experimental pharmacology & physiology 20070301

• Effector peptides of the renin-angiotensin system in the central mechanisms of acquired and innate behavior in thirst in rats.

  Neuroscience and behavioral physiology 20070301

• CYP2C9 variant modifies blood pressure-lowering response to losartan in Type 1 diabetic patients with nephropathy.

  Diabetic medicine : a journal of the British Diabetic Association 20070301

• Usefulness of either or both left and right bundle branch block at baseline or during follow-up for predicting death in patients following acute myocardial infarction.

  The American journal of cardiology 20070301

• Predictors of antihypertensive drug responses: initial data from a placebo-controlled, randomized, cross-over study with four antihypertensive drugs (The GENRES Study).

  American journal of hypertension 20070301

• Angiotensin-converting enzyme inhibitor enhances liver regeneration following partial hepatectomy: involvement of bradykinin B2 and angiotensin AT1 receptors.

  Biological & pharmaceutical bulletin 20070301

• Comparison of increasing doses of olmesartan medoxomil, losartan potassium, and valsartan in patients with essential hypertension.

  Journal of clinical hypertension (Greenwich, Conn.) 20070301

• [Inhibitory effect of angiotensin blockade on hepatic fibrosis in common bile duct-ligated rats].

  The Korean journal of hepatology 20070301

• Evaluating drug prices, availability, affordability, and price components: implications for access to drugs in Malaysia.

  PLoS medicine 20070301

• Long-term efficacy of combination therapy with losartan and low-dose hydrochlorothiazide in patients with uncontrolled hypertension.

  International heart journal 20070301

• Impact of diabetes on cardiomyocyte apoptosis and connexin43 gap junction integrity: role of pharmacological modulation.

  International heart journal 20070301

• Therapeutic options in non-alcoholic steatohepatitis (NASH). Are all agents alike? Results of a preliminary study.

  Journal of gastrointestinal and liver diseases : JGLD 20070301

• Neuropsychiatric consequences of cardiovascular medications.

  Dialogues in clinical neuroscience 20070301

• [Medication of the month. Olmesartan medoxomil hydroclorothiazide (Olmetec Plus or Belsar Plus].

  Revue medicale de Liege 20070301

• Relation between serum uric acid and carotid intima-media thickness in healthy postmenopausal women.

  Internal and emergency medicine 20070301

• Antihypertensive and antioxidant action of amlodipine and vitamin C in patients of essential hypertension.

  Journal of clinical biochemistry and nutrition 20070301

• Variation in ACE activity affects myogenic differentiation in C2C12 cells.

  Biochemical and biophysical research communications 20070209

• Treatments with losartan or enalapril are equally sensitive to deterioration in renal function from cyclooxygenase inhibition.

  European journal of heart failure 20070201

• Renal injury in streptozotocin-diabetic Ren2-transgenic rats is mainly dependent on hypertension, not on diabetes.

  American journal of physiology. Renal physiology 20070201

• BOLD-MRI assessment of intrarenal oxygenation and oxidative stress in patients with chronic kidney allograft dysfunction.

  American journal of physiology. Renal physiology 20070201

• Potentiation of the antihypertensive action of losartan by peripheral overexpression of the ANG II type 2 receptor.

  American journal of physiology. Heart and circulatory physiology 20070201

• The role of angiotensin receptor-1 blockade on electromechanical changes induced by left ventricular hypertrophy and its regression.

  Cardiovascular research 20070201

• Left atrial size and risk of major cardiovascular events during antihypertensive treatment: losartan intervention for endpoint reduction in hypertension trial.

  Hypertension (Dallas, Tex. : 1979) 20070201

• Mineralocorticoid pretreatment enhances angiotensin II-induced neuronal excitation but not salt drinking in male Fischer rats.

  Journal of neuroendocrinology 20070201

• Enalapril and losartan affect lipid peroxidation in renal transplant recipients with renin-angiotensin system polymorphisms.

  Clinical biochemistry 20070201

• The role of renin-angiotensin system inhibition in the treatment of hypertension in metabolic syndrome: are all the angiotensin receptor blockers equal?

  Expert opinion on therapeutic targets 20070201

• Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states.

  Nature medicine 20070201

• Prospective randomized study comparing amiodarone vs. amiodarone plus losartan vs. amiodarone plus perindopril for the prevention of atrial fibrillation recurrence in patients with lone paroxysmal atrial fibrillation.

  European heart journal 20070201

• Reduction in arterial stiffness with angiotensin II antagonism and converting enzyme inhibition. A comparative study among malay hypertensive subjects with a known genetic profile.

  American journal of hypertension 20070201

• Angiotensin II type 1 receptor as a novel therapeutic target in rheumatoid arthritis: in vivo analyses in rodent models of arthritis and ex vivo analyses in human inflammatory synovitis.

  Arthritis and rheumatism 20070201

• Blood pressure reduction and antihypertensive medication use in the losartan intervention for endpoint reduction in hypertension (LIFE) study in patients with hypertension and left ventricular hypertrophy.

  Current medical research and opinion 20070201

• Potential mechanisms of stroke benefit favoring losartan in the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study.

  Current medical research and opinion 20070201

• ACE inhibitor bulks up muscle.

  Nature medicine 20070201

• Platelet aggregability in patients with hypertension treated with angiotensin II type 1 receptor blockers.

  Journal of atherosclerosis and thrombosis 20070201

• [Effect of integrin-linked kinase on renal tubular epithelial cell transdifferentiation in diabetic rats].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20070201

• Angiotensin II promotes the inflammatory response to CD40 ligation via TRAF-2.

  Vascular medicine (London, England) 20070201

• Angiotensin II-induced regulation of the expression and localization of iron metabolism-related genes in the rat kidney.

  Hypertension research : official journal of the Japanese Society of Hypertension 20070201

• [Cardiovascular peculiarities in hypertensive rats (Hsiah strain) after antihypertensive drug intervention during juvenile period of life].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20070201

• Effect of type-1 diabetes mellitus on the regulation of insulin and endothelin-1 receptors in rat hearts.

  Canadian journal of physiology and pharmacology 20070201

• Cardiovascular risk reduction by reversing endothelial dysfunction: ARBs, ACE inhibitors, or both? Expectations from the ONTARGET Trial Programme.

  Vascular health and risk management 20070201

• Moexipril and left ventricular hypertrophy.

  Vascular health and risk management 20070201

• Carvedilol in the treatment of chronic heart failure: lessons from the Carvedilol Or Metoprolol European Trial.

  Vascular health and risk management 20070201

• Trandolapril/verapamil combination in hypertensive diabetic patients.

  Vascular health and risk management 20070201

• Role of the vasodilator peptide angiotensin-(1-7) in cardiovascular drug therapy.

  Vascular health and risk management 20070201

• Effect of candesartan cilexetil on diabetic and non-diabetic hypertensive patients: meta-analysis of five randomized double-blind clinical trials.

  Vascular health and risk management 20070201

• Enalapril and losartan restored blood pressure and vascular reactivity in intrauterine undernourished rats.

  Life sciences 20070130

• Lipopolysaccharide activates calcineurin in ventricular myocytes.

  Journal of the American College of Cardiology 20070130

• Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy.

  Circulation research 20070105

• The effects of simvastatin, losartan, and combined therapy on soluble CD40 ligand in hypercholesterolemic, hypertensive patients.

  Atherosclerosis 20070101

• Cardiac sympathetic afferent stimulation augments the arterial chemoreceptor reflex in anesthetized rats.

  Journal of applied physiology (Bethesda, Md. : 1985) 20070101

• Role of brain angiotensin AT1 receptor in the carbachol-induced natriuresis and expression of nNOS in the locus coeruleus and proximal convoluted tubule.

  Physiological research 20070101

• Role of PKC in the novel synergistic action of urotensin II and angiotensin II and in urotensin II-induced vasoconstriction.

  American journal of physiology. Heart and circulatory physiology 20070101

• The role of angiotensin II in stress urinary incontinence: A rat model.

  Neurourology and urodynamics 20070101

• Concentration-dependent mode of interaction of angiotensin II receptor blockers with uric acid transporter.

  The Journal of pharmacology and experimental therapeutics 20070101

• Endothelium-derived steroidogenic factor enhances angiotensin II-stimulated aldosterone release by bovine zona glomerulosa cells.

  Endocrinology 20070101

• Activation of endothelin-a receptors contributes to angiotensin-induced suppression of renal sensory nerve activation.

  Hypertension (Dallas, Tex. : 1979) 20070101

• Increased sympathetic activity in rats submitted to chronic intermittent hypoxia.

  Experimental physiology 20070101

• Simultaneous determination of losartan, EXP-3174 and hydrochlorothiazide in plasma via fully automated 96-well-format-based solid-phase extraction and liquid chromatography-negative electrospray tandem mass spectrometry.

  Analytical and bioanalytical chemistry 20070101

• Angiotensin II-induced MAPK phosphorylation mediated by Ras and/or phospholipase C-dependent phosphorylations but not by protein kinase C phosphorylation in cultured rat vascular smooth muscle cells.

  Pharmacology 20070101

• Amelioration of established diabetic nephropathy by combined treatment with SMP-534 (antifibrotic agent) and losartan in db/db mice.

  Nephron. Experimental nephrology 20070101

• Simply removing pressure doesn't work, but youthful drug-taking prevents hereditary mid-life failure.

  Journal of hypertension 20070101

• Transient AT1 receptor-inhibition in prehypertensive spontaneously hypertensive rats results in maintained cardiac protection until advanced age.

  Journal of hypertension 20070101

• Analysis of antihypertensive drugs in the heart of animal models: a proteomic approach.

  Methods in molecular biology (Clifton, N.J.) 20070101

• Apoptosis and proliferation of mesangial cells isolated from kidneys undergoing compensatory growth following contralateral nephrectomy: role of the renin-angiotensin system.

  Medical science monitor : international medical journal of experimental and clinical research 20070101

• Selective AT1 receptor antagonism enhances sympathetically mediated vasoconstriction in man.

  Clinical pharmacology and therapeutics 20070101

• Do valsartan and losartan have the same effects in the treatment of coronary artery disease?

  Circulation journal : official journal of the Japanese Circulation Society 20070101

• Proteomic identification of 14-3-3zeta as an adapter for IGF-1 and Akt/GSK-3beta signaling and survival of renal mesangial cells.

  International journal of biological sciences 20070101

• Intrarenal oxidative stress and augmented angiotensinogen are precedent to renal injury in Zucker diabetic fatty rats.

  International journal of biological sciences 20070101

• Angiotensin type 1 receptor antagonist losartan, reduces MPTP-induced degeneration of dopaminergic neurons in substantia nigra.

  Molecular neurodegeneration 20070101

• Renal allograft protection with angiotensin II type 1 receptor antagonists.

  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070101

• Evaluation of the cost savings and clinical outcomes of switching patients from atorvastatin to simvastatin and losartan to candesartan in a Primary Care setting.

  International journal of clinical practice 20070101

• Actions by angiotensin II on esophageal contractility in humans.

  Gastroenterology 20070101

• Impact of simvastatin and losartan on antiinflammatory effect: in vitro study.

  Journal of cardiovascular pharmacology 20070101

• ACE inhibitor and AT1-receptor blocker attenuate the production of VEGF in mesothelial cells.

  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20070101

• The effects of angiotensin II and genetic hypertension upon extracellular nucleotide hydrolysis by rat platelet ectoenzymes.

  Thrombosis research 20070101

• Differential alteration of drug-metabolizing enzyme activities after cyclophosphamide/adriamycin administration in breast cancer patients.

  Methods and findings in experimental and clinical pharmacology 20070101

• AT1 receptors and the actin cytoskeleton during angiotensin II treatment.

  Journal of nephrology 20070101

• Inhibition of the renin-angiotensin system and the prevention of stroke.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101

• Comparison of higher dose of losartan treatment with losartan plus carvedilol and losartan plus ramipril in patients with glomerulonephritis and proteinuria.

  Renal failure 20070101

• Selective Modulators of PPAR-gamma Activity: Molecular Aspects Related to Obesity and Side-Effects.

  PPAR research 20070101

• Irbesartan for the treatment of hypertension in patients with the metabolic syndrome: a sub analysis of the Treat to Target post authorization survey. Prospective observational, two armed study in 14,200 patients.

  Cardiovascular diabetology 20070101

• Effect of losartan plus hydrochlorothiazide on nitric oxide status in 'nondipper' hypertensive patients.

  American journal of therapeutics 20070101

• Effect of losartan therapy on endothelial function in hypertensive patients.

  American journal of therapeutics 20070101

• Effect of AT(1) angiotensin II receptor antagonists on the sympathetic response to a cold pressor test in healthy volunteers.

  American journal of therapeutics 20070101

• Impact of losartan on stroke risk in hypertensive patients in primary care.

  Clinical drug investigation 20070101

• Atenolol as a comparator in outcome trials in hypertension: a correct choice in the past, but not for the future?

  Blood pressure 20070101

• Effects of telmisartan and losartan on insulin resistance in hypertensive patients with metabolic syndrome.

  Hypertension research : official journal of the Japanese Society of Hypertension 20070101

• LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome.

  PloS one 20070101

• CX3CR1 receptor is up-regulated in monocytes of coronary artery diseased patients: impact of pre-inflammatory stimuli and renin-angiotensin system modulators.

  Thrombosis research 20070101

• [Effect of losartan on the state of kidney function in rats with experimental hyperthyroidism].

  Eksperimental'naia i klinicheskaia farmakologiia 20070101

• A convenient catalyst system for microwave accelerated cross-coupling of a range of aryl boronic acids with aryl chlorides.

  Beilstein journal of organic chemistry 20070101

• Role of asymmetric dimethylarginine in inflammatory reactions by angiotensin II.

  Journal of vascular research 20070101

• Macrophage infiltration and cellular proliferation in the non-ischemic kidney and heart following prolonged unilateral renal ischemia.

  Nephron. Physiology 20070101

• Renoprotection provided by losartan in combination with pioglitazone is superior to renoprotection provided by losartan alone in patients with type 2 diabetic nephropathy.

  Kidney & blood pressure research 20070101

• Differential effects of losartan and candesartan on vasoconstrictor responses in the rat.

  Canadian journal of physiology and pharmacology 20070101

• Uric acid reduction: a new paradigm in the management of cardiovascular risk?

  Current medicinal chemistry 20070101

• Effect of angiotensin II on primary cardiac fibroblast matrix metalloproteinase activities.

  Perfusion 20070101

• Evaluation of the prevalence and economic burden of adverse drug reactions presenting to the medical emergency department of a tertiary referral centre: a prospective study.

  BMC clinical pharmacology 20070101

• Functional overload attenuates plantaris atrophy in tumor-bearing rats.

  BMC cancer 20070101

• Aliskiren: a review of its use in the management of hypertension.

  Drugs 20070101

• Direct inhibition of renin as a cardiovascular pharmacotherapy: focus on aliskiren.

  Cardiology in review 20070101

• Baseline glucose and left ventricular remodeling after acute myocardial infarction.

  Journal of diabetes and its complications 20070101

• Antiplatelet effect of losartan and telmisartan in patients with ischemic stroke.

  Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20070101

• A Marfan syndrome gene expression phenotype in cultured skin fibroblasts.

  BMC genomics 20070101

• Prevention of hypertension with or without renin-angiotensin system inhibition precludes nephrin loss in the early stage of experimental diabetes mellitus.

  Nephron. Physiology 20070101

• Influence of enalapril, quinapril and losartan on lipopolysaccharide (LPS)-induced serum concentrations of TNF-alpha, IL-1 beta, IL-6 in spontaneously hypertensive rats (SHR).

  Pharmacological reports : PR 20070101

• Angiotensin II receptor blockers decreased blood glucose levels: a longitudinal survey using data from electronic medical records.

  Cardiovascular diabetology 20070101

• Telmisartan/hydrochlorothiazide versus valsartan/hydrochlorothiazide in obese hypertensive patients with type 2 diabetes: the SMOOTH study.

  Cardiovascular diabetology 20070101

• Treating anemia of chronic kidney disease in the primary care setting: cardiovascular outcomes and management recommendations.

  Osteopathic medicine and primary care 20070101

• Updated meta-analytical approach to the efficacy of antihypertensive drugs in reducing blood pressure.

  Clinical drug investigation 20070101

• Medicinal importance of grapefruit juice and its interaction with various drugs.

  Nutrition journal 20070101

• Mesangiolytic glomerulopathy after radiotherapy and chemotherapy of gastric lymphoma.

  Internal medicine (Tokyo, Japan) 20070101

• Antihypertensive efficacy of amlodipine and losartan after two 'missed' doses in patients with mild to moderate essential hypertension.

  The Journal of international medical research 20070101

• Effect of the angiotensin receptor blocker irbesartan on metabolic parameters in clinical practice: the DO-IT prospective observational study.

  Cardiovascular diabetology 20070101

• Cost-effectiveness of losartan in diabetic nephropathy: a Greek perspective.

  Journal of nephrology 20070101

• Ambulatory blood pressure adds to explaining benefits of AT-1 receptor blockade in the treatment of left ventricular hypertrophy.

  Blood pressure 20070101

• Losartan versus atenolol on 24-hour ambulatory blood pressure. A LIFE substudy.

  Blood pressure 20070101

• Aliskiren: an oral renin inhibitor for the treatment of hypertension.

  Cardiology in review 20070101

• Angiotensin peptides regulate angiogenic activity in rat anterior pituitary tumour cell cultures.

  Endokrynologia Polska 20070101

• Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy.

  Experimental diabetes research 20070101

• Contractile effects of angiotensinogen and its multiple metabolization pathways on vessel walls.

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20070101

• [State of vasoregulative function of vascular endothelium and cardiohemodynamics in patients with chronic obstructive diseases of the lung (CODL) treated with losartan].

  Likars'ka sprava 20070101

• Carotid Body AT(4) Receptor Expression and its Upregulation in Chronic Hypoxia.

  The open cardiovascular medicine journal 20070101

• Effects of eprosartan on serum metabolic parameters in patients with essential hypertension.

  The open cardiovascular medicine journal 20070101

• Perindopril: the evidence of its therapeutic impact in hypertension.

  Core evidence 20070101

• A review of the renal system and diurnal variations of renal activity in livestock.

  Irish veterinary journal 20070101

• Anemia and heart failure: a cause of progression or only a consequence?

  Heart international 20070101

• [Alteration of signal transduction-associated gene expression in rat cardiac fibroblasts induced by blocking angiotensin II receptors].

  Sheng li xue bao : [Acta physiologica Sinica] 20061225

• Effects of losartan on angiotensin receptors in the hypertrophic rat heart.

  Regulatory peptides 20061210

• Relationship between insulin resistance and inflammatory markers and anti-inflammatory effect of losartan in patients with type 2 diabetes and hypertension.

  Clinica chimica acta; international journal of clinical chemistry 20061201

• Angiotensin II activates intermediate-conductance Ca2+ -activated K+ channels in arterial smooth muscle cells.

  Journal of molecular and cellular cardiology 20061201

• Involvement of G-protein βγ subunits on the influence of inhibitory α2-autoreceptors on the angiotensin AT1-receptor modulation of noradrenaline release in the rat vas deferens.

  Neurochemistry international 20061201

• Angiotensin II activates two cation conductances with distinct TRPC1 and TRPC6 channel properties in rabbit mesenteric artery myocytes.

  The Journal of physiology 20061201

• Translocation of AT1- and AT2-receptors by higher concentrations of angiotensin II in the smooth muscle cells of rat internal anal sphincter.

  The Journal of pharmacology and experimental therapeutics 20061201

• The relation of ambulatory blood pressure and pulse rate to retinopathy in type 1 diabetes mellitus: the renin-angiotensin system study.

  Ophthalmology 20061201

• Ligand-supported homology modeling of the human angiotensin II type 1 (AT(1)) receptor: insights into the molecular determinants of telmisartan binding.

  Proteins 20061201

• Expression and localization of PDGF-B, PDGF-D, and PDGF receptor in the kidney of angiotensin II-infused rat.

  Laboratory investigation; a journal of technical methods and pathology 20061201

• Centrally injected angiotensin II trans-synaptically activates angiotensin II-sensitive neurons in the anterior hypothalamic area of rats.

  Neuroscience letters 20061201

• Antihypertensive and renal protective effects of renin-angiotensin system blockade in uremic rats treated with erythropoietin.

  American journal of hypertension 20061201

• Effects of repeated green tea catechin administration on human cytochrome P450 activity.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20061201

• Prevention of interstitial fibrosis of renal allograft by angiotensin II blockade.

  Transplantation proceedings 20061201

• Treating hypertension in older people: Practical implications of achieving targets.

  Journal of the American Geriatrics Society 20061201

• [Effects of losartan on the levels of angiotensin II and its type-1 receptor in diabetic rat kidney].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20061201

• Heat shock protein 70 expression is associated with inhibition of renal tubule epithelial cell apoptosis during recovery from low-protein feeding.

  Cell stress & chaperones 20061201

• Chronic blockade of angiotensin II AT1-receptors increased cell-to-cell communication, reduced fibrosis and improved impulse propagation in the failing heart.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20061201

• Olmesartan medoxomil: current status of its use in monotherapy.

  Vascular health and risk management 20061201

• Olmesartan medoxomil combined with hydrochlorothiazide for the treatment of hypertension.

  Vascular health and risk management 20061201

• Sexual function in hypertensive patients receiving treatment.

  Vascular health and risk management 20061201

• Insulin resistance and plasma triglyceride level are differently related to cardiac hypertrophy and arterial stiffening in hypertensive subjects.

  Vascular health and risk management 20061201

• Assessment of cognitive function in patients with essential hypertension treated with lercanidipine.

  Vascular health and risk management 20061201

• Effects of losartan on urinary secretion of extracellular matrix and their modulators in type 2 diabetes mellitus patients with microalbuminuria.

  Clinical and investigative medicine. Medecine clinique et experimentale 20061201

• Effects of AT1 receptor-mediated endocytosis of extracellular Ang II on activation of nuclear factor-kappa B in proximal tubule cells.

  Annals of the New York Academy of Sciences 20061201

• Candesartan in heart failure.

  Clinical interventions in aging 20061201

• Uric acid and xanthine oxidase: future therapeutic targets in the prevention of cardiovascular disease?

  British journal of clinical pharmacology 20061201

• Response surface methodology for optimization of losartan potassium controlled release tablets.

  Journal of controlled release : official journal of the Controlled Release Society 20061128

• Angiotensin II-induced NADPH oxidase activation impairs insulin signaling in skeletal muscle cells.

  The Journal of biological chemistry 20061117

• Systemic inhibition of the angiotensin-converting enzyme limits lipopolysaccharide-induced lung neutrophil recruitment through both bradykinin and angiotensin II-regulated pathways.

  Journal of immunology (Baltimore, Md. : 1950) 20061115

• ACE inhibitors and aortic rupture.

  Lancet (London, England) 20061104

• Further studies on imidazo[4,5-b]pyridine AT1 angiotensin II receptor antagonists. Effects of the transformation of the 4-phenylquinoline backbone into 4-phenylisoquinolinone or 1-phenylindene scaffolds.

  Journal of medicinal chemistry 20061102

• Left ventricular assist device and drug therapy for the reversal of heart failure.

  The New England journal of medicine 20061102

• Effect of angiotensin II blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats.

  American journal of physiology. Heart and circulatory physiology 20061101

• Intracellular angiotensin II induces cell proliferation independent of AT1 receptor.

  American journal of physiology. Cell physiology 20061101

• Angiotensin II decreases system A amino acid transporter activity in human placental villous fragments through AT1 receptor activation.

  American journal of physiology. Endocrinology and metabolism 20061101

• Role of angiotensin II in retinal leukostasis in the diabetic rat.

  Experimental eye research 20061101

• Improved insulin sensitivity with the angiotensin II-receptor blocker losartan in patients with hypertension and other cardiovascular risk factors.

  Journal of human hypertension 20061101

• Renin-angiotensin system mediators and Raynaud's phenomenon.

  The Annals of pharmacotherapy 20061101

• Blockade of the renin-angiotensin system improves insulin sensitivity in thermal injury.

  Shock (Augusta, Ga.) 20061101

• Drug-disease interactions: losartan effect is not downregulated by rheumatoid arthritis.

  Journal of clinical pharmacology 20061101

• Lercanidipine is an effective and well tolerated antihypertensive drug regardless the cardiovascular risk profile: The LAURA study.

  International journal of clinical practice 20061101

• Inhibitory effects of angiotensin II receptor antagonists and leukotriene receptor antagonists on the transport of human organic anion transporter 4.

  The Journal of pharmacy and pharmacology 20061101

• Blockade of the renin-angiotensin system attenuates sarcolemma and sarcoplasmic reticulum remodeling in chronic diabetes.

  Annals of the New York Academy of Sciences 20061101

• European Academy of Paediatrics, Barcelona, Spain, October 7-10, 2006. Abstracts.

  European journal of pediatrics 20061101

• Downregulation of peroxisme proliferator activated receptor gamma co-activator 1alpha in diabetic rats.

  International heart journal 20061101

• Neuronal angiotensin II type 1 receptor upregulation in heart failure: activation of activator protein 1 and Jun N-terminal kinase.

  Circulation research 20061027

• Effects of tight blood pressure control on glomerular hypertrophy in a model of genetic hypertension and experimental diabetes mellitus.

  Life sciences 20061026

• [Cost-effectiveness of treatment of high blood pressure with losartan in Denmark].

  Ugeskrift for laeger 20061016

• Photosensitized degradation of losartan potassium in an extemporaneous suspension formulation.

  Journal of pharmaceutical and biomedical analysis 20061011

• Lipid peroxidation is not increased in heart failure patients on modern pharmacological therapy.

  International journal of cardiology 20061010

• Increased renal vascular reactivity to ANG II after unilateral nephrectomy in the rat involves 20-HETE.

  American journal of physiology. Regulatory, integrative and comparative physiology 20061001

• Candesartan cilexetil in children with hypertension or proteinuria: preliminary data.

  Pediatric nephrology (Berlin, Germany) 20061001

• Regional hemodynamic effects of neutral endopeptidase inhibition and angiotensin (AT(1)) receptor antagonism alone or in combination in conscious spontaneously hypertensive rats.

  The Journal of pharmacology and experimental therapeutics 20061001

• Internal mammary artery smooth muscle cells resist migration and possess high antioxidant capacity.

  Cardiovascular research 20061001

• Time to abandon microalbuminuria?

  Kidney international 20061001

• AT1 antagonist modulates activin-like kinase 5 and TGF-beta receptor II in the developing kidney.

  Pediatric nephrology (Berlin, Germany) 20061001

• Blood pressure is the major driving force for plaque formation in aortic-constricted ApoE-/- mice.

  Journal of hypertension 20061001

• Electrocardiographic strain pattern and left ventricular diastolic function in hypertensive patients with left ventricular hypertrophy: the LIFE study.

  Journal of hypertension 20061001

• Anti-inflammatory effects of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: Potential benefits for the prevention of atrial fibrillation.

  European heart journal 20061001

• Efficacy and safety of angiotensin II receptor blockade in elderly patients with diabetes.

  Diabetes care 20061001

• Aldosterone breakthrough during therapy with angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in proteinuric patients with immunoglobulin A nephropathy.

  Nephrology (Carlton, Vic.) 20061001

• Regulation of angiotensin II-Induced Krüppel-like factor 5 expression in vascular smooth muscle cells.

  Biological & pharmaceutical bulletin 20061001

• Effect on blood pressure control of switching from valsartan monotherapy to losartan/hydrochlorothiazide in Asian patients with hypertension: results of a multicentre open-label trial.

  Current medical research and opinion 20061001

• Antihypertensive agents have different ability to modulate arterial pressure and heart rate variability in 2K1C rats.

  American journal of hypertension 20061001

• Hypertension, diuretics, and uric acid.

  American journal of hypertension 20061001

• Ang II and Ang III modulate PTZ seizure threshold in non-stressed and stressed mice: possible involvement of noradrenergic mechanism.

  Neuropeptides 20061001

• [Effect of asymmetric dimethylarginine on platelet-aggregation and losartan intervention in spontaneous hypertensive rat models].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20061001

• Lipid peroxidation and renal injury in renal ischemic reperfusion: effect ofangiotensin inhibition.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20061001

• AT1 receptor blockade prevents microvascular dysfunction induced by ischemia/reperfusion injury.

  Journal of atherosclerosis and thrombosis 20061001

• A multicenter, randomized, double-blind, parallel-group trial of the antihypertensive efficacy and tolerability of a combination of once-daily losartan 100 mg/hydrochlorothiazide 12.5 mg compared with losartan 100-mg monotherapy in the treatment of mild to severe essential hypertension.

  Clinical therapeutics 20061001

• The effect of losartan and amlodipine on serum adiponectin in Japanese adults with essential hypertension.

  Clinical therapeutics 20061001

• [Efficacy and safety of olmesartan medoxomil versus losartan potassium in Chinese patients with mild to moderate essential hypertension].

  Zhonghua xin xue guan bing za zhi 20061001

• [The effects of angiotensin II receptor blockers in hypertensive patients complicating hyperuricaemia].

  Zhonghua xin xue guan bing za zhi 20061001

• Strategies for primary and secondary stroke prevention.

  Clinical cardiology 20061001

• Statin use and survival in patients with chronic heart failure--results from two observational studies with 5200 patients.

  International journal of cardiology 20060920

• Regression of electrocardiographic left ventricular hypertrophy and decreased incidence of new-onset atrial fibrillation in patients with hypertension.

  JAMA 20060913

• Biphasic actions of angiotensin IV on renal blood flow in the rat.

  Regulatory peptides 20060911

• Modulation of kinin B1 receptor expression by endogenous angiotensin II in hypertensive rats.

  Regulatory peptides 20060911

• Angiotensin-II is a putative neurotransmitter in lactate-induced panic-like responses in rats with disruption of GABAergic inhibition in the dorsomedial hypothalamus.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060906

• Central angiotensin II receptors mediate hemodynamic response variability to stressors.

  American journal of physiology. Regulatory, integrative and comparative physiology 20060901

• Central angiotensin AT1-receptor blockade affects thermoregulation and running performance in rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20060901

• Effects of i.c.v. losartan on the angiotensin II-mediated vasopressin release and hypothalamic fos expression in near-term ovine fetuses.

  Peptides 20060901

• Signaling pathways involved with the stimulatory effect of angiotensin II on vacuolar H+-ATPase in proximal tubule cells.

  Pflugers Archiv : European journal of physiology 20060901

• Abnormal renovascular parathyroid hormone-1 receptor in hypertension: Primary defect or secondary to angiotensin ii type 1 receptor activation?

  Endocrinology 20060901

• Molecular activation of PPARgamma by angiotensin II type 1-receptor antagonists.

  Vascular pharmacology 20060901

• The effect of angiotensin 1-7 on tyrosine kinases activity in rat anterior pituitary.

  Biochemical and biophysical research communications 20060901

• Nox2, Ca2+, and protein kinase C play a role in angiotensin II-induced free radical production in nucleus tractus solitarius.

  Hypertension (Dallas, Tex. : 1979) 20060901

• Angiotensin II induced contraction of rat and human small intestinal wall musculature in vitro.

  Acta physiologica (Oxford, England) 20060901

• Angiotensin type 1 receptor antagonists induce human in-vitro adipogenesis through peroxisome proliferator-activated receptor-gamma activation.

  Journal of hypertension 20060901

• Proposed new score to rate the strength of evidence and its application to large-scale clinical trials of angiotensin-receptor blockers.

  Circulation journal : official journal of the Japanese Circulation Society 20060901

• The effect of single oral low-dose losartan on posture-related sodium handling in post-TIPS ascites-free cirrhosis.

  Hepatology (Baltimore, Md.) 20060901

• Reduction of salt sensitivity in stroke-prone spontaneously hypertensive rats administered an AT1 receptor antagonist during suckling.

  American journal of hypertension 20060901

• Acute renal failure during lisinopril and losartan therapy for proteinuria.

  Pharmacotherapy 20060901

• The role of angiotensin II in the regulation of breast cancer cell adhesion and invasion.

  Endocrine-related cancer 20060901

• Effects of monotherapy and combination therapy on blood pressure control and target organ damage: a randomized prospective intervention study in a large population of hypertensive patients.

  Journal of clinical hypertension (Greenwich, Conn.) 20060901

• [Intracellular signal transduction of vascular injury in insulin resistance].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20060901

• [Palmoplantar hyperkeratosis associated with losartan].

  Actas dermo-sifiliograficas 20060901

• Renin angiotensin aldosterone system blockade and renal disease in patients with type 2 diabetes: a subanalysis of Japanese patients from the RENAAL study.

  Clinical and experimental nephrology 20060901

• Japanese subpopulation analysis of the RENAAL, the landmark trial, is welcomed by our society.

  Clinical and experimental nephrology 20060901

• In utero losartan withdrawal and subsequent development of fetal inferior vena cava thrombosis.

  Obstetrics and gynecology 20060901

• Angiotensins II and IV modulate adrenocortical cell proliferation in ovariectomized rats.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20060901

• [Effect of losartan on sarcoplasmic reticulum Ca2+ handing proteins in heart failure rabbit].

  Zhonghua xin xue guan bing za zhi 20060901

• A review of telmisartan in the treatment of hypertension: blood pressure control in the early morning hours.

  Vascular health and risk management 20060901

• Nebivolol: a novel beta-blocker with nitric oxide-induced vasodilatation.

  Vascular health and risk management 20060901

• A large scale study of angiotensin II inhibition therapy in an elderly population: the CHANCE study.

  Vascular health and risk management 20060901

• Endothelin ETA receptors and endothelium partially mediate the positive inotropic and lusitropic effects of angiotensin II.

  European journal of pharmacology 20060821

• [Plus point -- risk reduction].

  MMW Fortschritte der Medizin 20060817

• [Kidney protection leads to heart protection, too].

  MMW Fortschritte der Medizin 20060817

• Localized accumulation of angiotensin II and production of angiotensin-(1-7) in rat luteal cells and effects on steroidogenesis.

  American journal of physiology. Endocrinology and metabolism 20060801

• AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases.

  American journal of physiology. Renal physiology 20060801

• Role of bradykinin B1 and B2 receptors in normal blood pressure regulation.

  American journal of physiology. Endocrinology and metabolism 20060801

• ANG II enhances contractile responses via PI3-kinase p110 delta pathway in aortas from diabetic rats with systemic hyperinsulinemia.

  American journal of physiology. Heart and circulatory physiology 20060801

• Angiotensin-converting enzyme and angiotensin II receptor subtype 1 inhibitors restitute hypertensive internal anal sphincter in the spontaneously hypertensive rats.

  The Journal of pharmacology and experimental therapeutics 20060801

• Angiotensin II disrupts inhibitory avoidance memory retrieval.

  Hormones and behavior 20060801

• Macrophage migration inhibitory factor in the PVN attenuates the central pressor and dipsogenic actions of angiotensin II.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060801

• Angiotensin receptor blockade decreases fibrosis and fibroblast expression in a rat model of unilateral ureteral obstruction.

  The Journal of urology 20060801

• Prospective randomized study comparing amiodarone vs. amiodarone plus losartan vs. amiodarone plus perindopril for the prevention of atrial fibrillation recurrence in patients with lone paroxysmal atrial fibrillation.

  European heart journal 20060801

• Dual blockade of angiotensin II with enalapril and losartan reduces proteinuria in hypertensive patients with type 2 diabetes.

  Endocrine journal 20060801

• Effects of angiotensin II on connexin 43 of VSMCs in arteriosclerosis.

  Journal of Zhejiang University. Science. B 20060801

• Effect of losartan and hydrochlorothiazide on exercise tolerance in exertional hypertension and left ventricular diastolic dysfunction.

  The American journal of cardiology 20060801

• Short-term administration of an angiotensin-receptor antagonist in patients with impaired fasting glucose improves insulin sensitivity and increases free IGF-I.

  European journal of endocrinology 20060801

• N-terminal brain natriuretic peptide predicted cardiovascular events stronger than high-sensitivity C-reactive protein in hypertension: a LIFE substudy.

  Journal of hypertension 20060801

• [Effect of angiotensin II and its receptor antagonist on electrophysiology and L-type calcium current in guinea cardiac myocytes].

  Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20060801

• Regression of alterations in retinal microcirculation following treatment for arterial hypertension.

  Journal of clinical hypertension (Greenwich, Conn.) 20060801

• Sexual dimorphism in the renin-angiotensin system in aging spontaneously hypertensive rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20060801

• Sanguinarine downregulates AT1a gene expression in a hypertensive rat model.

  Journal of cardiovascular pharmacology 20060801

• [Electrocardiographic findings].

  Nihon rinsho. Japanese journal of clinical medicine 20060801

• [LIFE].

  Nihon rinsho. Japanese journal of clinical medicine 20060801

• [HOSP study].

  Nihon rinsho. Japanese journal of clinical medicine 20060801

• Tamoxifen inhibits cytochrome P450 2C9 activity in breast cancer patients.

  Journal of chemotherapy (Florence, Italy) 20060801

• Mice deficient in telomerase activity develop hypertension because of an excess of endothelin production.

  Circulation 20060725

• Centrally administered interleukin-1 beta sensitizes to the central pressor action of angiotensin II.

  Brain research 20060719

• The contribution of brain angiotensin II to the baroreflex regulation of renal sympathetic nerve activity in conscious normotensive and hypertensive rats.

  The Journal of physiology 20060715

• Effects of losartan + L-arginine on nitric oxide production, endothelial cell function, and hemodynamic variables in patients with heart failure secondary to coronary heart disease.

  The American journal of cardiology 20060715

• Proposal of a new binding orientation for non-peptide AT1 antagonists: homology modeling, docking and three-dimensional quantitative structure-activity relationship analysis.

  Journal of medicinal chemistry 20060713

• Direct positive chronotropic action by angiotensin II in the isolated mouse atrium.

  Life sciences 20060710

• Chronic blockade of the angiotensin II receptor has a differential effect on adipose and vascular PAI-1 in OLETF rats.

  Diabetes research and clinical practice 20060701

• Significance of changes in TNF-alpha and IL-10 levels in the progression of heart failure subsequent to myocardial infarction.

  American journal of physiology. Heart and circulatory physiology 20060701

• Cardiac fibrogenesis in magnesium deficiency: a role for circulating angiotensin II and aldosterone.

  American journal of physiology. Heart and circulatory physiology 20060701

• ANG II-induced cardiac molecular and cellular events: role of aldosterone.

  American journal of physiology. Heart and circulatory physiology 20060701

• Angiotensin II formation in the kidney and nephrosclerosis in Ren-2 hypertensive rats.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701

• Synthesis, binding studies and in vivo biological evaluation of novel non-peptide antihypertensive analogues.

  Bioorganic & medicinal chemistry 20060701

• Losartan attenuates bleomycin induced lung fibrosis by increasing prostaglandin E2 synthesis.

  Thorax 20060701

• Changes in vascular reactivity following administration of isoproterenol for 1 week: a role for endothelial modulation.

  British journal of pharmacology 20060701

• Cyclosporin A stimulates apical Na+/H+ exchange in LLC-PK1/PKE20 proximal tubular cells.

  Pediatric nephrology (Berlin, Germany) 20060701

• Employer-paid nonmedical costs for patients with diabetes and end-stage renal disease.

  Preventing chronic disease 20060701

• Amodiaquine, its desethylated metabolite, or both, inhibit the metabolism of debrisoquine (CYP2D6) and losartan (CYP2C9) in vivo.

  European journal of clinical pharmacology 20060701

• The assessment of left ventricular hypertrophy in hypertension.

  Journal of hypertension 20060701

• Gestational therapy with an angiotensin II receptor antagonist and transient renal failure in a premature infant.

  American journal of perinatology 20060701

• [Evidence-based therapy of Raynaud's syndrome].

  Zeitschrift fur Rheumatologie 20060701

• Regulation of angiogenic factors in angiotensin II infusion model in association with tubulointerstitial injuries.

  American journal of hypertension 20060701

• [Treatment of chronic renal insufficiency with losartan and traditional Chinese drug for invigorating spleen and kidney].

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20060701

• Role of anemia in progression of chronic kidney disease.

  Seminars in nephrology 20060701

• Risk scores for predicting outcomes in patients with type 2 diabetes and nephropathy: the RENAAL study.

  Clinical journal of the American Society of Nephrology : CJASN 20060701

• Effect of eprosartan on the sympathetic response to cold pressor test in healthy volunteers.

  Autonomic neuroscience : basic & clinical 20060630

• Cross-talk between angiotensin II and glucagon receptor signaling mediates phosphorylation of mitogen-activated protein kinases ERK 1/2 in rat glomerular mesangial cells.

  Biochemical pharmacology 20060614

• Losartan reduces monocyte chemoattractant protein-1 expression in aortic tissues of 2K1C hypertensive rats.

  International journal of cardiology 20060607

• Effects of central injection of angiotensin-converting-enzyme inhibitor and angiotensin type 1 receptor antagonist on the brain NF-kappaB and AP-1 activities of rats given LPS.

  Peptides 20060601

• Intracellular ANG II induces cytosolic Ca2+ mobilization by stimulating intracellular AT1 receptors in proximal tubule cells.

  American journal of physiology. Renal physiology 20060601

• Angiotensin II AT2 receptors inhibit proximal tubular Na+-K+-ATPase activity via a NO/cGMP-dependent pathway.

  American journal of physiology. Renal physiology 20060601

• Renal mitochondrial dysfunction in spontaneously hypertensive rats is attenuated by losartan but not by amlodipine.

  American journal of physiology. Regulatory, integrative and comparative physiology 20060601

• Pressor responses to alligator Angiotensin I and some analogs in the spectacled caiman (Caiman crocodilus).

  General and comparative endocrinology 20060601

• The effect of losartan compared with atenolol on the incidence of revascularization in patients with hypertension and electrocardiographic left ventricular hypertrophy. The LIFE study.

  Journal of human hypertension 20060601

• Angiotensin II type 2 receptor agonist directly inhibits proximal tubule sodium pump activity in obese but not in lean Zucker rats.

  Hypertension (Dallas, Tex. : 1979) 20060601

• Role of EGF receptor activation in angiotensin II-induced renal epithelial cell hypertrophy.

  Journal of the American Society of Nephrology : JASN 20060601

• Oxidative stress during peritoneal dialysis: implications in functional and structural changes in the membrane.

  Kidney international 20060601

• Renin increments the inward calcium current in the failing heart.

  Journal of hypertension 20060601

• Therapeutic potential of angiotensin receptor blockers in hypertension.

  Expert opinion on investigational drugs 20060601

• Losartan appears cost-effective for reducing stroke in people with hypertension and left ventricular hypertrophy.

  Evidence-based cardiovascular medicine 20060601

• The lipopolysaccharide-induced up-regulation of bradykinin B2-receptor in the mouse heart is mediated by tumor necrosis factor-alpha and angiotensin II.

  Biological & pharmaceutical bulletin 20060601

• [Clinical utility of angiotensin II receptor antagonist].

  Nihon rinsho. Japanese journal of clinical medicine 20060601

• Design and rationale of the Clinical Outcomes Utilizing Revascularization and Aggressive DruG Evaluation (COURAGE) trial Veterans Affairs Cooperative Studies Program no. 424.

  American heart journal 20060601

• The parathyroid hormone-related protein system and diabetic nephropathy outcome in streptozotocin-induced diabetes.

  Kidney international 20060601

• Nephrotic syndrome and IgA nephropathy in polycystic kidney disease.

  Clinical and experimental nephrology 20060601

• Ventricular hypertrophy and hypertension: prognostic elements and implications for management.

  Herz 20060601

• [Angiotensin II AT1 receptor antagonists as antiinflammatory and gastric protection drugs].

  Acta gastroenterologica Latinoamericana 20060601

• Review of the molecular pharmacology of Losartan and its possible relevance to stroke prevention in patients with hypertension.

  Clinical therapeutics 20060601

• New developments in clinically relevant mechanisms and treatment of hyperuricemia.

  Current rheumatology reports 20060601

• Effects of ACE inhibition and angiotensin II receptor blockade on glomerular basement membrane protein excretion and charge selectivity in type 2 diabetic patients.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20060601

• A review of Perindopril in the reduction of cardiovascular events.

  Vascular health and risk management 20060601

• Valsartan in the treatment of heart attack survivors.

  Vascular health and risk management 20060601

• Leptin and hypertension in obesity.

  Vascular health and risk management 20060601

• Fenofibrate: a novel formulation (Triglide) in the treatment of lipid disorders: a review.

  International journal of nanomedicine 20060601

• Evidence suggesting that angiotensins released not via synaptic inputs are involved in the basal activity of anterior hypothalamic neurons in rats.

  Neuroscience letters 20060529

• [Hypertensive patient with enlarged heart. Caution, risk of atrial fibrillation!].

  MMW Fortschritte der Medizin 20060525

• Dual mechanisms of angiotensin-induced activation of mouse sympathetic neurones.

  The Journal of physiology 20060515

• Drug shows promise for marfan syndrome.

  JAMA 20060503

• AT1 receptor-activated signaling mediates angiotensin IV-induced renal cortical vasoconstriction in rats.

  American journal of physiology. Renal physiology 20060501

• Analysis of the mechanisms underlying the vasorelaxant action of angiotensin II in the isolated rat carotid.

  Life sciences 20060501

• A randomized trial comparing losartan with amlodipine as initial therapy for hypertension in the early post-transplant period.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060501

• A comparison study of cerebral protection using Ginkgo biloba extract and Losartan on stroked rats.

  Neuroscience letters 20060501

• Foetal kidney maldevelopment in maternal use of angiotensin II type I receptor antagonists.

  Pediatric nephrology (Berlin, Germany) 20060501

• Association of hemoglobin delivery with left ventricular structure and function in hypertensive patients: Losartan Intervention for End Point Reduction in Hypertension Study.

  Hypertension (Dallas, Tex. : 1979) 20060501

• Renal risk and renoprotection among ethnic groups with type 2 diabetic nephropathy: a post hoc analysis of RENAAL.

  Kidney international 20060501

• Losartan, an angiotensin-II receptor antagonist, retards the progression of advanced renal insufficiency.

  The Tohoku journal of experimental medicine 20060501

• Angiotensin receptor blockers: new considerations in their mechanism of action.

  Journal of clinical hypertension (Greenwich, Conn.) 20060501

• Perindopril/indapamide combination in the first-line treatment of hypertension and end-organ protection.

  Expert review of cardiovascular therapy 20060501

• Managing hypertension in high-risk patients: lessons and promises from the STRATHE and ADVANCE trials.

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20060501

• [Experimental study of the therapeutic effect and mechanism of 'Shenxian Fuyuan capsule' on chronic renal failure in rats].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060501

• [Protective effect of losartan on endothelial cells exposed to high glucose levels in vitro].

  Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20060501

• [Grouping-related bias of effects of the same anti-hypertensive drugs in non-doubleblind randomized trials: a meta-analysis in Chinese hypertension clinical literature].

  Zhonghua xin xue guan bing za zhi 20060501

• Confidence intervals for an exposure adjusted incidence rate difference with applications to clinical trials.

  Statistics in medicine 20060430

• New NO-releasing pharmacodynamic hybrids of losartan and its active metabolite: design, synthesis, and biopharmacological properties.

  Journal of medicinal chemistry 20060420

• NAD(P)H oxidase in paraventricular nucleus contributes to the effect of angiotensin II on cardiac sympathetic afferent reflex.

  Brain research 20060412

• Medicine. Old drug, new hope for Marfan syndrome.

  Science (New York, N.Y.) 20060407

• Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome.

  Science (New York, N.Y.) 20060407

• Effects of high sodium intake diet on the vascular reactivity to phenylephrine on rat isolated caudal and renal vascular beds: Endothelial modulation.

  Life sciences 20060404

• Differential effect of losartan in female and male spontaneously hypertensive rats.

  Life sciences 20060404

• Glycogen synthase kinase 3beta together with 14-3-3 protein regulates diabetic cardiomyopathy: effect of losartan and tempol.

  FEBS letters 20060403

• An unexpected role for angiotensin II in the link between dietary salt and proximal reabsorption.

  The Journal of clinical investigation 20060403

• Increased natriuretic peptide receptor A and C gene expression in rats with pressure-overload cardiac hypertrophy.

  American journal of physiology. Heart and circulatory physiology 20060401

• Effect of angiotensin II receptor blockade on autonomic nervous system function in patients with essential hypertension.

  American journal of physiology. Heart and circulatory physiology 20060401

• Angiotensin-mediated increase in renal sympathetic nerve discharge within the PVN: role of nitric oxide.

  American journal of physiology. Regulatory, integrative and comparative physiology 20060401

• Angiotensin II attenuates endothelium-dependent responses in the cerebral microcirculation through nox-2-derived radicals.

  Arteriosclerosis, thrombosis, and vascular biology 20060401

• Losartan improves resistance artery lesions and prevents CTGF and TGF-beta production in mild hypertensive patients.

  Kidney international 20060401

• Tetrazole compounds: the effect of structure and pH on Caco-2 cell permeability.

  Journal of pharmaceutical sciences 20060401

• Increased vascular angiotensin II binding capacity and ET-1 release in young cardiomyopathic hamsters.

  Vascular pharmacology 20060401

• The positive inotropic effect of angiotensin II: role of endothelin-1 and reactive oxygen species.

  Hypertension (Dallas, Tex. : 1979) 20060401

• Analysis of screening and confirmatory tests in the diagnosis of primary aldosteronism: need for a standardized protocol.

  Journal of hypertension 20060401

• Reductions in albuminuria and in electrocardiographic left ventricular hypertrophy independently improve prognosis in hypertension: the LIFE study.

  Journal of hypertension 20060401

• Acute renal failure induced by an angiotensin II receptor antagonist in a 14-year-old boy with reflux nephropathy.

  Pediatric nephrology (Berlin, Germany) 20060401

• All-trans retinoic acid inhibited angiotensin II-induced increase in cell growth and collagen secretion of neonatal cardiac fibroblasts.

  Acta pharmacologica Sinica 20060401

• Losartan: lessons learned from the RENAAL study.

  Expert opinion on pharmacotherapy 20060401

• Economic evaluation of angiotensin receptor blockers in type 2 diabetes, hypertension, and nephropathy.

  Journal of the American Society of Nephrology : JASN 20060401

• Angiotensin II stimulates the synthesis of vascular endothelial growth factor through the p38 mitogen activated protein kinase pathway in cultured mouse podocytes.

  Journal of molecular endocrinology 20060401

• Chemometric determination of naproxen sodium and pseudoephedrine hydrochloride in tablets by HPLC.

  Chemical & pharmaceutical bulletin 20060401

• The pleiotropic effects of angiotensin receptor blockers.

  Journal of clinical hypertension (Greenwich, Conn.) 20060401

• Prospects for the prevention of stroke.

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20060401

• Arteriolar remodeling in essential hypertension: are connective tissue growth factor and transforming growth factor involved?

  Kidney international 20060401

• A placebo-controlled comparison of the efficacy and tolerability of candesartan cilexetil, 8 mg, and losartan, 50 mg, as monotherapy in patients with essential hypertension, using 36-h ambulatory blood pressure monitoring.

  International journal of clinical practice 20060401

• Malaysian Indians are genetically similar to Caucasians: CYP2C9 polymorphism.

  Journal of clinical pharmacy and therapeutics 20060401

• Lercanidipine and losartan effects on blood pressure and fibrinolytic parameters.

  The Kaohsiung journal of medical sciences 20060401

• [Effect of probucol and losartan on growth factors after balloon angioplasty in rabbits].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20060401

• In vitro availability of atorvastatin in presence of losartan.

  Pakistan journal of pharmaceutical sciences 20060401

• Angiotensin II antagonists: clinical experience in the treatment of hypertension, prevention of cardiovascular outcomes and renal protection in diabetic nephropathy and proteinuria.

  Arquivos brasileiros de endocrinologia e metabologia 20060401

• [Long-term clinical efficacy of losartan or perindopril combination therapy with low-dose amiodarone in patients with paroxysmal atrial fibrillation].

  Zhonghua xin xue guan bing za zhi 20060401

• Losartan attenuates phospholipase C isozyme gene expression in hypertrophied hearts due to volume overload.

  Journal of cellular and molecular medicine 20060401

• Does losartan alter urinary levels of connective tissue growth factor in patients with diabetic nephropathy?

  Nature clinical practice. Nephrology 20060401

• [AT1 receptor antagonist lorsartan and organ protection. Managing hypertension a different way].

  MMW Fortschritte der Medizin 20060330

• Impact of diabetes mellitus on regression of electrocardiographic left ventricular hypertrophy and the prediction of outcome during antihypertensive therapy: the Losartan Intervention For Endpoint (LIFE) Reduction in Hypertension Study.

  Circulation 20060328

• Structure elucidation and conformational study of V8: a novel synthetic non peptide AT(1) antagonist.

  Journal of pharmaceutical and biomedical analysis 20060318

• [Antihypertensive therapy: risk stratification in diabetes and cardiac diseases].

  MMW Fortschritte der Medizin 20060316

• Differential effects of prenatal exposure to dexamethasone or cortisol on circulatory control mechanisms mediated by angiotensin II in the central nervous system of adult sheep.

  The Journal of physiology 20060315

• AT1 receptor antagonism ameliorates acute pancreatitis-associated pulmonary injury.

  Regulatory peptides 20060315

• Design and synthesis of new tetrazolyl- and carboxy-biphenylylmethyl-quinazolin-4-one derivatives as angiotensin II AT1 receptor antagonists.

  Journal of medicinal chemistry 20060309

• Short-term nitric oxide inhibition induces progressive nephropathy after regression of initial renal injury.

  American journal of physiology. Renal physiology 20060301

• Interaction between AT1 and AT2 receptors during postinfarction left ventricular remodeling.

  American journal of physiology. Heart and circulatory physiology 20060301

• AT1 receptors are necessary for eccentric training-induced hypertrophy and strength gains in rat skeletal muscle.

  Experimental physiology 20060301

• Regulation of peroxisome proliferator-activated receptor gamma activity by losartan metabolites.

  Hypertension (Dallas, Tex. : 1979) 20060301

• Enhanced endothelin synthesis by endothelial cells exposed to sera from pregnant rats with decreased uterine perfusion.

  Hypertension (Dallas, Tex. : 1979) 20060301

• The importance of early antihypertensive efficacy: the role of angiotensin II receptor blocker therapy.

  Journal of human hypertension 20060301

• Angiotensin II acutely decreases myocardial stiffness: a novel AT1, PKC and Na+/H+ exchanger-mediated effect.

  British journal of pharmacology 20060301

• Evidence supporting a functional role for intracellular renin in the brain.

  Hypertension (Dallas, Tex. : 1979) 20060301

• Differential protein expression in hypertrophic heart with and without hypertension in spontaneously hypertensive rats.

  Proteomics 20060301

• The effect of AST-120 on the single-dose pharmacokinetics of losartan and losartan acid (E-3174) in healthy subjects.

  Journal of clinical pharmacology 20060301

• Targeting effective blood pressure control with angiotensin receptor blockers.

  International journal of clinical practice 20060301

• Does albuminuria predict cardiovascular outcomes on treatment with losartan versus atenolol in patients with diabetes, hypertension, and left ventricular hypertrophy? The LIFE study.

  Diabetes care 20060301

• Long-term effects of a losartan- compared with an atenolol-based treatment regimen on carotid artery plaque development in hypertensive patients with left ventricular hypertrophy: ICARUS, a LIFE substudy.

  Journal of clinical hypertension (Greenwich, Conn.) 20060301

• Upregulation of osteopontin gene expression in diabetic rat proximal tubular cells revealed by microarray profiling.

  Kidney international 20060301

• RAS blockade decreases blood pressure and proteinuria in transgenic mice overexpressing rat angiotensinogen gene in the kidney.

  Kidney international 20060301

• Enalapril suppresses ventricular remodeling after acute myocardial infarction more effectively than losartan.

  Evidence-based cardiovascular medicine 20060301

• Comparative bioavailability of two losartan formulations in healthy human volunteers after a single dose administration.

  International journal of clinical pharmacology and therapeutics 20060301

• Predictors of self-reported noncompliance with antihypertensive drug treatment: a prospective cohort study.

  The Canadian journal of cardiology 20060301

• Effects of angiotensin-converting enzyme inhibitors or an angiotensin receptor blocker in combination with aspirin and cilostazol on in-stent restenosis.

  International heart journal 20060301

• [Effect of captopril on pulmonary vascular remodeling induced by left-to-right shunt in rats].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060301

• Blockade of AT1 receptors by losartan did not affect renin gene expression in kidney medulla.

  General physiology and biophysics 20060301

• Effects of eprosartan on target organ protection.

  Vascular health and risk management 20060301

• Angiotensin II stimulates intercellular adhesion molecule-1 via an AT1 receptor/nuclear factor-kappaB pathway in brain microvascular endothelial cells.

  Life sciences 20060216

• Watchdog rules that Merck violated the UK industry code of practice.

  BMJ (Clinical research ed.) 20060211

• Endothelin-1 expression in vascular adventitial fibroblasts.

  American journal of physiology. Heart and circulatory physiology 20060201

• Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes.

  American journal of physiology. Cell physiology 20060201

• High glucose and angiotensin II increase beta1 integrin and integrin-linked kinase synthesis in cultured mouse podocytes.

  Cell and tissue research 20060201

• Chronic angiotensin II AT1 receptor blockade increases cerebral cortical microvessel density.

  American journal of physiology. Heart and circulatory physiology 20060201

• Influence of commonly used drugs on the accuracy of cystatin C-derived glomerular filtration rate.

  Pediatric nephrology (Berlin, Germany) 20060201

• Role of blood cell-associated AT1 receptors in the microvascular responses to hypercholesterolemia.

  Arteriosclerosis, thrombosis, and vascular biology 20060201

• Coronary artery superoxide production and nox isoform expression in human coronary artery disease.

  Arteriosclerosis, thrombosis, and vascular biology 20060201

• Antiatherogenic effects of angiotensin receptor antagonism in mild renal dysfunction.

  Journal of the American Society of Nephrology : JASN 20060201

• Angiotensin-II type 1 receptor-mediated hypertension in D4 dopamine receptor-deficient mice.

  Hypertension (Dallas, Tex. : 1979) 20060201

• Model of the whole rat AT1 receptor and the ligand-binding site.

  Journal of molecular modeling 20060201

• Variation in the lipoprotein lipase gene influences exercise-induced left ventricular growth.

  Journal of molecular medicine (Berlin, Germany) 20060201

• The IGF-I system and the renal and haemodynamic effects of losartan in normotensive patients with type 2 diabetes mellitus: a randomized clinical trial.

  Clinical endocrinology 20060201

• Angiotensin II type 1 receptor blockade improves beta-cell function and glucose tolerance in a mouse model of type 2 diabetes.

  Diabetes 20060201

• Inhibitory effect of 5-fluorouracil on cytochrome P450 2C9 activity in cancer patients.

  Basic & clinical pharmacology & toxicology 20060201

• Effect of losartan versus candesartan on uric acid, renal function, and fibrinogen in patients with hypertension and hyperuricemia associated with diuretics.

  American journal of hypertension 20060201

• Remodeling and angiotensin II responses of the uterine arcuate arteries of pregnant rats are altered by low- and high-sodium intake.

  Reproduction (Cambridge, England) 20060201

• Comparison of the protein profile of established and regressed hypertension-induced left ventricular hypertrophy.

  Journal of proteome research 20060201

• Effects of atenolol and losartan on baroreflex sensitivity and heart rate variability in uncomplicated essential hypertension.

  Journal of cardiovascular pharmacology 20060201

• [Protective effect of losartan on injury induced by ox-LDL in endothelial cells and the relationship with asymmetric dimethylarginine].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20060201

• Increased migration of vascular adventitial fibroblasts from spontaneously hypertensive rats.

  Hypertension research : official journal of the Japanese Society of Hypertension 20060201

• [The role of AT1 receptor in the changes in TH immunoreactivity of LC induced by brain cholinergic stimulation].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20060201

• Role of angiotensin II receptor subtypes in porcine basilar artery: functional, radioligand binding, and cell culture studies.

  Life sciences 20060125

• Randomized placebo-controlled study on the effects of losartan and carvedilol on albuminuria in renal transplant recipients.

  Transplantation 20060115

• Inhibitory effect of angiotensin II receptor antagonist on hepatic stellate cell activation in non-alcoholic steatohepatitis.

  World journal of gastroenterology 20060114

• Novel polymer monolith microextraction using a poly(methacrylic acid-ethylene glycol dimethacrylate) monolith and its application to simultaneous analysis of several angiotensin II receptor antagonists in human urine by capillary zone electrophoresis.

  Journal of chromatography. A 20060113

• Thrombospondin 1 mediates angiotensin II induction of TGF-beta activation by cardiac and renal cells under both high and low glucose conditions.

  Biochemical and biophysical research communications 20060113

• NAD(P)H oxidase-derived reactive oxygen species regulate angiotensin-II induced adventitial fibroblast phenotypic differentiation.

  Biochemical and biophysical research communications 20060106

• Electrocardiographic strain pattern and prediction of new-onset congestive heart failure in hypertensive patients: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) study.

  Circulation 20060103

• Angiotensin II induces the expression of tissue factor and its mechanism in human monocytes.

  Thrombosis research 20060101

• Role of myofibrillogenesis regulator-1 in myocardial hypertrophy.

  American journal of physiology. Heart and circulatory physiology 20060101

• Meta-analysis of large outcome trials of angiotensin receptor blockers in hypertension.

  Journal of human hypertension 20060101

• Cellular cholesterol efflux to plasma from proteinuric patients is elevated and remains unaffected by antiproteinuric treatment.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060101

• Adrenergic origin of very low-frequency blood pressure oscillations in the unanesthetized rat.

  American journal of physiology. Heart and circulatory physiology 20060101

• Role of insulin-sensitizing property of telmisartan, a commercially available angiotensin II type 1 receptor blocker in preventing the development of atrial fibrillation.

  Medical hypotheses 20060101

• A non-radioactive method for angiotensin II receptor binding studies using the rat liver.

  Journal of pharmacological and toxicological methods 20060101

• Angiotensin II and angiotensin II receptor blocker modulate the arrhythmogenic activity of pulmonary veins.

  British journal of pharmacology 20060101

• Effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricaemia in Chinese population.

  Journal of human hypertension 20060101

• Treating the metabolic syndrome using angiotensin receptor antagonists that selectively modulate peroxisome proliferator-activated receptor-gamma.

  The international journal of biochemistry & cell biology 20060101

• Angiotensin II-dependent vascular alterations in young cardiomyopathic hamsters: role for oxidative stress.

  Vascular pharmacology 20060101

• Role of angiotensin type-1 and angiotensin type-2 receptors in the expression of vascular integrins in angiotensin II-infused rats.

  Hypertension (Dallas, Tex. : 1979) 20060101

• Losartan attenuates bleomycin-induced pulmonary fibrosis in rats.

  Respiration; international review of thoracic diseases 20060101

• Blockade of the renin-angiotensin-aldosterone system: a key therapeutic strategy to reduce renal and cardiovascular events in patients with diabetes.

  Journal of hypertension 20060101

• Blockade of angiotensin II and aging: is the spontaneously hypertensive rat a suitable model?

  Journal of hypertension 20060101

• Angiotensin II type 1 receptor antagonism improves endothelial vasodilator function in L-NAME-induced hypertensive rats by a kinin-dependent mechanism.

  Journal of hypertension 20060101

• Impact of antihypertensive treatments on erectile responses in aging spontaneously hypertensive rats.

  Journal of hypertension 20060101

• Cost-effectiveness of losartan-based therapy in patients with hypertension and left ventricular hypertrophy: a UK-based economic evaluation of the Losartan Intervention for Endpoint reduction in hypertension (LIFE) study.

  Journal of human hypertension 20060101

• Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms.

  Kidney international 20060101

• Effect of losartan and amlodipine on left ventricular diastolic function in patients with mild-to-moderate hypertension (J-ELAN): rationale and design.

  Circulation journal : official journal of the Japanese Circulation Society 20060101

• Effect of quinapril or losartan alone and in combination on left ventricular systolic and diastolic functions in asymptomatic patients with diabetic autonomic neuropathy.

  Journal of diabetes and its complications 20060101

• Angiotensin II antagonists--therapeutic benefits spanning the cardiovascular disease continuum from hypertension to heart failure and diabetic nephropathy.

  Current medical research and opinion 20060101

• The impact of suppressing the renin-angiotensin system on atrial fibrillation.

  Journal of clinical pharmacology 20060101

• Common angiotensin receptor blockers may directly modulate the immune system via VDR, PPAR and CCR2b.

  Theoretical biology & medical modelling 20060101

• Losartan and prevention of atrial fibrillation recurrence in hypertensive patients.

  Journal of cardiovascular pharmacology 20060101

• Effects of a fenofibrate/losartan combination on the plasma concentration and urinary excretion of purine bases.

  International journal of clinical pharmacology and therapeutics 20060101

• [The 'LOTHAR' study: evaluation of efficacy and tolerability of the fixed combination of amlodipine and losartan in the treatment of essential hypertension].

  Arquivos brasileiros de cardiologia 20060101

• Enhanced effect of combined treatment with SMP-534 (antifibrotic agent) and losartan in diabetic nephropathy.

  American journal of nephrology 20060101

• Evaluation of enalapril+losartan treatment with cardiopulmonary exercise test in patients with left ventricular dysfunction.

  Angiology 20060101

• Effects of antihypertensive treatment with angiotensin II receptor blockers on lipid profile: an open multi-drug comparison trial.

  Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20060101

• A five-year comparison of the renal protective effects of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in patients with non-diabetic nephropathy.

  Internal medicine (Tokyo, Japan) 20060101

• Transactivation of the epidermal growth factor receptor by angiotensin II in glomerular podocytes.

  Nephron. Experimental nephrology 20060101

• [Effector peptides of the brain renin-angiotensin system in central mechanisms of learned and natural forms of drinking behavior in rats].

  Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20060101

• Methods underpinning national clinical guidelines for hypertension: describing the evidence shortfall.

  BMC health services research 20060101

• A cost-utility analysis of losartan versus atenolol in the treatment of hypertension with left ventricular hypertrophy.

  PharmacoEconomics 20060101

• Clinical usefulness of the angiotensin II receptor antagonist losartan in patients with portal hypertensive gastropathy.

  Hepato-gastroenterology 20060101

• Initial experience with bosentan therapy in patients considered ineligible for heart transplantation because of severe pulmonary hypertension.

  Clinical transplantation 20060101

• Impact of therapy initiation with amlodipine or losartan on hemodynamic endpoints and JNC-VI blood pressure stage.

  American journal of therapeutics 20060101

• Relevance of the stroma and epithelial-mesenchymal transition (EMT) for the rheumatic diseases.

  Arthritis research & therapy 20060101

• Hyperbaric oxygen treatment augments the efficacy of a losartan regime in an experimental nephrotic syndrome model.

  Nephron. Experimental nephrology 20060101

• [Current views about the role of purin metabolism disorders in patients with arterial hypertension and losartan potentialities].

  Kardiologiia 20060101

• [Resistant hypertension and paradox effect in patient with hemodialysis treatment].

  Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20060101

• Aldosterone synthase (CYP11B2)-344T/C polymorphism and renoprotective response to losartan treatment in diabetic nephropathy.

  Scandinavian journal of clinical and laboratory investigation 20060101

• Thyrotropin-releasing hormone in rat heart: effect of swelling, angiotensin II and renin gene.

  Acta physiologica (Oxford, England) 20060101

• Influence of arterial hypertension treated with losartan on skin healing in rats.

  Acta cirurgica brasileira 20060101

• Effects of angiotensin II receptor blockade-based therapy with losartan on left ventricular hypertrophy and geometry in previously treated hypertensive patients.

  Blood pressure 20060101

• Pharmacoeconomics of angiotensin II antagonists in type 2 diabetic patients with nephropathy: implications for decision making.

  PharmacoEconomics 20060101

• The impact of losartan on the lifetime incidence of end-stage renal disease and costs in patients with type 2 diabetes and nephropathy.

  PharmacoEconomics 20060101

• Different effects of simvastatin and losartan on cytokine levels in coronary artery disease.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101

• Epidemiology and cardiovascular risk factors of aortic stenosis.

  Cardiovascular ultrasound 20060101

• A concise history of gout and hyperuricemia and their treatment.

  Arthritis research & therapy 20060101

• Epidemiology, risk factors, and lifestyle modifications for gout.

  Arthritis research & therapy 20060101

• Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics.

  Arthritis research & therapy 20060101

• Treatment of heart failure in Dutch general practice.

  BMC family practice 20060101

• [Isolation and purification of the process impurity in losartan by reversed-phase column chromatography].

  Se pu = Chinese journal of chromatography 20060101

• Arterial hypertension and stroke prevention: an update.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20060101

• Cardiomyopathy, familial dilated.

  Orphanet journal of rare diseases 20060101

• C-reactive protein (CRP)-lowering agents.

  Cardiovascular drug reviews 20060101

• Peripheral arteriopathy of the lower limbs in a patient with severe congenital thrombocytopenia.

  Internal and emergency medicine 20060101

• Management of patients with uncontrolled arterial hypertension--the role of electronic compliance monitoring, 24-h ambulatory blood pressure monitoring and Candesartan/HCTZ.

  BMC cardiovascular disorders 20060101

• A randomized, double blind, cross-over, placebo-controlled clinical trial to assess the effects of Candesartan on the insulin sensitivity on non diabetic, non hypertense subjects with dysglyce mia and abdominal obesity. 'ARAMIA'.

  Trials 20060101

• Antiproteinuric effect of losartan in non-diabetic renal disease is not dependent on ACE insertion/deletion polymorphism.

  Kidney & blood pressure research 20060101

• Angiotensin II regulates extraneuronal dopamine uptake in the kidney.

  Nephron. Physiology 20060101

• Amlodipine versus angiotensin II receptor blocker; control of blood pressure evaluation trial in diabetics (ADVANCED-J).

  BMC cardiovascular disorders 20060101

• The effect of different antihypertensive drugs on cavernous tissue in experimental chronic renal insufficiency.

  Journal of nephrology 20060101

• Effects of angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, and their combination on microalbuminuria in normotensive patients with type 2 diabetes.

  Advances in therapy 20060101

• Effects of captopril and losartan on thermal and chemical induced pain in mice.

  Indian journal of physiology and pharmacology 20060101

• Management of high-risk patients with hypertension and left ventricular hypertrophy in Germany: differences between cardiac specialists in the inpatient and outpatient setting.

  BMC public health 20060101

• Exercise performance during losartan- or atenolol-based treatment in hypertensive patients with electrocardiographic left ventricular hypertrophy (a LIFE substudy).

  Blood pressure 20060101

• [Renal hemodynamics and development of renal fibrotic lesions during hypertension].

  Archives des maladies du coeur et des vaisseaux 20060101

• [Renin-angiotensin system inhibition and cardiac and renal alteration induced by a high sodium diet in rat].

  Archives des maladies du coeur et des vaisseaux 20060101

• [Angiotensin receptor blockers and cardiac rhythm disorders].

  Archives des maladies du coeur et des vaisseaux 20060101

• Does long-term losartan- vs atenolol-based antihypertensive treatment influence collagen markers differently in hypertensive patients? A LIFE substudy.

  Blood pressure 20060101

• Target organ damage and cardiovascular complications in patients with hypertension and type 2 diabetes in Spain: a cross-sectional study.

  Cardiovascular diabetology 20060101

• Changes in heart failure medications in patients hospitalised and discharged.

  BMC family practice 20060101

• Long-term treatment with an ACE inhibitor or an AT1 antagonist avoids hypertension-induced inflammation in the kidney.

  Journal of nephrology 20060101

• Bioequivalence study of two losartan formulations administered orally in healthy male volunteers.

  Arzneimittel-Forschung 20060101

• Early left ventricular gene expression profile in response to increase in blood pressure.

  Blood pressure 20060101

• Could garlic be an useful adjuvant therapy in adriamycin heart failure?

  Kathmandu University medical journal (KUMJ) 20060101

• Should beta-blockers continue to open against hypertension?

  Indian heart journal 20060101

• Interactions between angiotensin I and acetylcholine on rat left main bronchial rings.

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20060101

• Antihypertensive and cardiovascular effects of combined blockade of renin-angiotensin system with ACE inhibitor and angiotensin II type 1 receptor blocker in hypertensive patients: A 24-week randomized controlled double-dummy trial.

  Heart international 20060101

• Polymorphism of the ACE Gene in dialysis patients: overexpression of DD genotype in type 2 diabetic end-stage renal failure patients.

  Yonsei medical journal 20051231

• Effects of losartan and irbesartan administration on brain angiotensinogen mRNA levels.

  European journal of pharmacology 20051228

• Effects of six months losartan administration on liver fibrosis in chronic hepatitis C patients: a pilot study.

  World journal of gastroenterology 20051228

• Effects of intracerebroventricular losartan on angiotensin II-mediated pressor responses and c-fos expression in near-term ovine fetus.

  The Journal of comparative neurology 20051226

• Cholinergic systems in the posterior hypothalamic nucleus are involved in blood pressure decrease-induced excitation of anterior hypothalamic area neurons in rats.

  Neuroscience letters 20051223

• Interaction between arginine vasopressin and angiotensin II receptors in the central regulation of sodium balance.

  Regulatory peptides 20051215

• Biocompatible in-tube solid-phase microextraction coupled to HPLC for the determination of angiotensin II receptor antagonists in human plasma and urine.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051215

• Renal effects of long-term leptin infusion and preventive role of losartan treatment in rats.

  Regulatory peptides 20051215

• Plasma levels of soluble tumor necrosis factor receptor type I during the acute phase following complicated myocardial infarction predicts survival in high-risk patients.

  Journal of the American College of Cardiology 20051206

• Preserving cardiac function in the hypertensive patient: why renal parameters hold the key.

  European heart journal 20051201

• Prevention of pulmonary vascular remodeling and of decreased BMPR-2 expression by losartan therapy in shunt-induced pulmonary hypertension.

  American journal of physiology. Heart and circulatory physiology 20051201

• Angiotensin II-induced venoconstriction involves both AT1 and AT2 receptors and is counterbalanced by nitric oxide.

  Peptides 20051201

• Possible pathophysiologic mechanisms supporting the superior stroke protection of angiotensin receptor blockers compared to angiotensin-converting enzyme inhibitors: clinical and experimental evidence.

  Journal of human hypertension 20051201

• Blockade of angiotensin II AT1 receptors inhibits pressor action of centrally administered interleukin-1beta in Sprague Dawley rats.

  Neuropeptides 20051201

• R561C missense mutation in the SMARCAL1 gene associated with mild Schimke immuno-osseous dysplasia.

  Pediatric nephrology (Berlin, Germany) 20051201

• Reversal of fructose-induced hypertension and insulin resistance by chronic losartan treatment is independent of AT2 receptor activation in rats.

  Journal of hypertension 20051201

• Blockade of angiotensin II provides additional benefits in hypertension- and ageing-related cardiac and vascular dysfunctions beyond its blood pressure-lowering effects.

  Journal of hypertension 20051201

• Oxidative stress contributes to the enhanced expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells from spontaneously hypertensive rats.

  Journal of hypertension 20051201

• Blood pressure and proteinuria after cessation of a brief renin-angiotensin system blockade in young and adult Lyon hypertensive rats.

  Journal of cardiovascular pharmacology 20051201

• Hospitalizations for new heart failure among subjects with diabetes mellitus in the RENAAL and LIFE studies.

  The American journal of cardiology 20051201

• Effect of Losartan on left ventricular diastolic function in patients with nonobstructive hypertrophic cardiomyopathy.

  The American journal of cardiology 20051201

• Role of AT-1 receptor in regulation of vascular MCP-1, IL-6, PAI-1, MAP kinase, and matrix expressions in obesity.

  Kidney international 20051201

• Serum concentration of potassium in chronic heart failure patients administered spironolactone plus furosemide and either enalapril maleate, losartan potassium or candesartan cilexetil.

  Journal of clinical pharmacy and therapeutics 20051201

• Anemia management and chronic renal failure progression.

  Kidney international. Supplement 20051201

• The role of the new beta-blockers in treating cardiovascular disease.

  American journal of hypertension 20051201

• Antihypertensive agents for aging patients who are at risk for cognitive dysfunction.

  Current hypertension reports 20051201

• Angiotensin II via AT1 receptor accelerates arterial thrombosis in renovascular hypertensive rats.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20051201

• Effect of losartan on slowing progression of chronic allograft nephropathy.

  Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20051201

• Do losartan and atenolol have differential effects on BNP and central haemodynamic parameters?

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20051201

• Cardiovascular disease in diabetic nephropathy patients: cell adhesion molecules as potential markers?

  Vascular health and risk management 20051201

• [Effects of losartan, ramipril and their combination on left ventricular remodeling and function in spontaneous hypertensive rats].

  Zhonghua yi xue za zhi 20051130

• [Hypertension and stroke: new publications in 2005].

  MMW Fortschritte der Medizin 20051117

• Losartan blocks drinking and cFos expression induced by central ornithine vasotocin in rats.

  Physiology & behavior 20051115

• Patterns of antihypertensive therapy in new users of angiotensin II-receptor blockers.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20051115

• Effect of losartan pretreatment on kidney lipid content after unilateral obstruction in rats.

  Cellular and molecular biology (Noisy-le-Grand, France) 20051108

• Angiotensin II type I antagonist on oxidative stress and heat shock protein 70 (HSP 70) expression in obstructive nephropathy.

  Cellular and molecular biology (Noisy-le-Grand, France) 20051108

• Effect of omapatrilat on the aging process of the normal rat.

  Cellular and molecular biology (Noisy-le-Grand, France) 20051108

• Effects of angiotensin II receptor antagonist, Losartan on the apoptosis, proliferation and migration of the human pancreatic stellate cells.

  World journal of gastroenterology 20051107

• Circulating level of gelatinase activity predicts ventricular remodeling in patients with acute myocardial infarction.

  International journal of cardiology 20051102

• Involvement of Src tyrosine kinase and mitogen-activated protein kinase in the facilitation of calcium channels in rat nucleus of the tractus solitarius by angiotensin II.

  The Journal of physiology 20051101

• Inhibition of the renin-angiotensin system prevents free fatty acid-induced acute endothelial dysfunction in humans.

  Arteriosclerosis, thrombosis, and vascular biology 20051101

• Regression of existing glomerulosclerosis by inhibition of aldosterone.

  Journal of the American Society of Nephrology : JASN 20051101

• Chronic At1 receptor blockade alters the mechanisms mediating hypoxic dilation in middle cerebral arteries.

  Journal of cardiovascular pharmacology 20051101

• Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors.

  Kidney international 20051101

• Angiotensin II inhibition attenuates postexercise proteinuria in rats.

  International journal of sports medicine 20051101

• Comparative study of taste disturbance by losartan and perindopril in healthy volunteers.

  Journal of clinical pharmacology 20051101

• Angiotensin II activates matrix metalloproteinase type II and mimics age-associated carotid arterial remodeling in young rats.

  The American journal of pathology 20051101

• Janus kinase-2 signaling mediates apoptosis in rat cardiomyocytes.

  Vascular pharmacology 20051101

• A116C angiotensin II type 1 receptor gene polymorphism may predict hemodynamic response to losartan in patients with cirrhosis and portal hypertension.

  The American journal of gastroenterology 20051101

• Aortic valve sclerosis and albuminuria predict cardiovascular events independently in hypertension: a losartan intervention for endpoint-reduction in hypertension (LIFE) substudy.

  American journal of hypertension 20051101

• Simvastatin and losartan enhance nitric oxide and reduce oxidative stress in salt-induced hypertension.

  American journal of hypertension 20051101

• NF-kappaB and chemokine-cytokine expression in renal tubulointerstitium in experimental hyperoxaluria. Role of the renin-angiotensin system.

  Urological research 20051101

• [Effect of losartan on expression of Janus kinase 2 and signal transducer and activator of transcription 3 in glomeruli of diabetic rats].

  Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20051101

• Update on the efficacy of angiotensin receptor blockers in treatment of hypertension.

  The American journal of managed care 20051101

• Valsartan abolishes most of the memory-improving effects of intracerebroventricular angiotensin II in rats.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20051101

• Evaluation of intrarenal hemodynamics by Doppler ultrasonography for renoprotective effect of angiotensin receptor blockade.

  Clinical nephrology 20051101

• The effect of angiotensin receptor blockade ARB on the regression of left ventricular hypertrophy in hemodialysis patients: comparison between patients with D allele and non-D allele ACE gene polymorphism.

  Clinical nephrology 20051101

• Comparison of fixed-dose combinations of telmisartan/hydrochlorothiazide 40/12.5 mg and 80/12.5 mg and a fixed-dose combination of losartan/hydrochlorothiazide 50/12.5 mg in mild to moderate essential hypertension: pooled analysis of two multicenter, prospective, randomized, open-label, blinded-end point (PROBE) trials.

  Clinical therapeutics 20051101

• Losartan and acute myocardial infarction in insulin-resistant Zucker fatty rats: reduced ventricular arrhythmias and improved survival.

  Canadian journal of physiology and pharmacology 20051101

• Angiotensin receptor blockade and exercise capacity in adults with systemic right ventricles: a multicenter, randomized, placebo-controlled clinical trial.

  Circulation 20051018

• Black pearl in the LIFE study: angiotensin-II receptor blockade on atrial fibrillation for future personalized medicine.

  Journal of the American College of Cardiology 20051018

• Cholinergic stimulation in the posterior hypothalamic nucleus activates angiotensin II-sensitive neurons in the anterior hypothalamic area of rats.

  Brain research bulletin 20051015

• Mechanisms of action of mycophenolate mofetil in preventing acute and chronic allograft rejection.

  Transplantation 20051015

• NADPH oxidase-derived superoxide anion mediates angiotensin II-induced pressor effect via activation of p38 mitogen-activated protein kinase in the rostral ventrolateral medulla.

  Circulation research 20051014

• Vasoactive prostanoids are generated from arachidonic acid by COX-1 and COX-2 in the mouse.

  American journal of physiology. Heart and circulatory physiology 20051001

• Superiority of combination of thiazide with angiotensin-converting enzyme inhibitor or AT1-receptor blocker over thiazide alone on renoprotection in L-NAME/SHR.

  American journal of physiology. Renal physiology 20051001

• Glomerular abundance of nephrin and podocin in experimental nephrotic syndrome: different effects of antiproteinuric therapies.

  American journal of physiology. Renal physiology 20051001

• Adverse effects of left ventricular hypertrophy in the reduction of endpoints in NIDDM with the angiotensin II antagonist losartan (RENAAL) study.

  Diabetologia 20051001

• Peripheral sympatholytic actions of four AT1 antagonists: are they relevant for long-term antihypertensive efficacy?

  Journal of hypertension 20051001

• Neutralization of transforming growth factor-beta attenuates hypertension and prevents renal injury in uremic rats.

  Journal of hypertension 20051001

• Antihypertensive, antiproteinuric therapy and myocardial infarction and stroke prevention.

  Current hypertension reports 20051001

• Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart.

  Hypertension (Dallas, Tex. : 1979) 20051001

• Low sodium intake induces an increase in renal monoamine oxidase activity in the rat. Involvement of an angiotensin II dependent mechanism.

  Acta physiologica Scandinavica 20051001

• Enalapril suppresses ventricular remodeling more effectively than losartan in patients with acute myocardial infarction.

  American heart journal 20051001

• Apoptosis of circulating lymphocyte in rats with unilateral ureteral obstruction: role of angiotensin II.

  Nephrology (Carlton, Vic.) 20051001

• TGF-beta and TNF-alpha producing effects of losartan and amlodipine on human mononuclear cell culture.

  Nephrology (Carlton, Vic.) 20051001

• Losartan reduces the costs of diabetic end-stage renal disease: an Asian perspective.

  Nephrology (Carlton, Vic.) 20051001

• [ARB II in chronic heart failure. Coincidences and divergences. Class effect?].

  Revista clinica espanola 20051001

• Angiotensin II receptor antagonists and heart failure: angiotensin-converting-enzyme inhibitors remain the first-line option.

  Prescrire international 20051001

• Impact of the angiotensin II receptor antagonist, losartan, on myocardial fibrosis in patients with end-stage renal disease: assessment by ultrasonic integrated backscatter and biochemical markers.

  Hypertension research : official journal of the Japanese Society of Hypertension 20051001

• Complement activation in angiotensin II-induced organ damage.

  Circulation research 20050930

• [Schimke's immuno-osseous dysplasia as an explanation for the rare combination of disproportionately short stature and the nephrotic syndrome].

  Nederlands tijdschrift voor geneeskunde 20050924

• Losartan metabolite EXP3179 activates Akt and endothelial nitric oxide synthase via vascular endothelial growth factor receptor-2 in endothelial cells: angiotensin II type 1 receptor-independent effects of EXP3179.

  Circulation 20050920

• The effect of losartan versus atenolol on cardiovascular morbidity and mortality in patients with hypertension taking aspirin: the Losartan Intervention for Endpoint Reduction in hypertension (LIFE) study.

  Journal of the American College of Cardiology 20050906

• Angiotensin II inhibits bTREK-1 K+ channels in adrenocortical cells by separate Ca2+- and ATP hydrolysis-dependent mechanisms.

  The Journal of biological chemistry 20050902

• Native and oxidized low-density lipoproteins stimulate endothelin-converting enzyme-1 expression in human endothelial cells.

  Biochemical and biophysical research communications 20050902

• Losartan renography for the detection of renal artery stenosis: comparison with captopril renography and evaluation of dose and timing.

  European journal of nuclear medicine and molecular imaging 20050901

• ANG III induces expression of inducible transcription factors of AP-1 and Krox families in rat brain.

  American journal of physiology. Regulatory, integrative and comparative physiology 20050901

• Increased counteracting effect of eNOS and nNOS on an alpha1-adrenergic rise in total peripheral vascular resistance in spontaneous hypertensive rats.

  Cardiovascular research 20050901

• Angiotensin II mediates glutathione depletion, transforming growth factor-beta1 expression, and epithelial barrier dysfunction in the alcoholic rat lung.

  American journal of physiology. Lung cellular and molecular physiology 20050901

• Enhanced osmotic responsiveness in angiotensin AT1a receptor deficient mice: evidence for a role for AT1b receptors.

  Experimental physiology 20050901

• Design, synthesis, and evaluation of novelly substituted benzimidazole compounds as angiotensin II receptor antagonists.

  Bioorganic & medicinal chemistry letters 20050901

• Combined angiotensin II type 1 and type 2 receptor blockade on vascular remodeling and matrix metalloproteinases in resistance arteries.

  Hypertension (Dallas, Tex. : 1979) 20050901

• Angiotensin receptors and actions in guinea pig enteric nervous system.

  American journal of physiology. Gastrointestinal and liver physiology 20050901

• Mycophenolate mofetil ameliorates nephropathy in the obese Zucker rat.

  Kidney international 20050901

• Coexpression of AT1 and AT2 receptors by human fibroblasts is associated with resistance to angiotensin II.

  Peptides 20050901

• Cardiovascular morbidity and mortality in hypertensive patients with lower versus higher risk: a LIFE substudy.

  Hypertension (Dallas, Tex. : 1979) 20050901

• Antihypertensive treatment and sympathetic excitation.

  Hypertension (Dallas, Tex. : 1979) 20050901

• Integrating research and development: the emergence of rational drug design in the pharmaceutical industry.

  Studies in history and philosophy of biological and biomedical sciences 20050901

• Inhibition of the renin-angiotensin system and cardio-renal protection: focus on losartan and angiotensin receptor blockade.

  Expert opinion on pharmacotherapy 20050901

• Effects of eplerenone versus losartan in patients with low-renin hypertension.

  American heart journal 20050901

• An economic evaluation of the 2003 European Society of Hypertension-European Society of Cardiology guidelines for the management of mild-to-moderate hypertension in Greece.

  American journal of hypertension 20050901

• ACE inhibitor and AT1 antagonist stimulate duodenal HCO3- secretion mediated by a common pathway - involvement of PG, NO and bradykinin.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050901

• [Do beta-blockers prevent coronary events in hypertensive patients?].

  Archives des maladies du coeur et des vaisseaux 20050901

• [Effects of Losartan on expression of heme oxygenases in volume-overloaded rats with left-to-right shunt].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20050901

• New therapeutic strategies for systemic sclerosis--a critical analysis of the literature.

  Clinical & developmental immunology 20050901

• Are multiple angiotensin receptor types involved in angiotensin (1-7) actions on isolated rat portal vein.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20050901

• Lercanidipine in hypertension.

  Vascular health and risk management 20050901

• AT1 receptor in paraventricular nucleus mediates the enhanced cardiac sympathetic afferent reflex in rats with chronic heart failure.

  Autonomic neuroscience : basic & clinical 20050831

• Anterior hypothalamic neurons respond to blood pressure changes via gamma-aminobutyric acid and angiotensins in rats.

  Neuroscience letters 20050826

• ANG II increases 2-deoxyglucose uptake in mouse embryonic stem cells.

  Life sciences 20050826

• Angiotensin II directly induces muscle protein catabolism through the ubiquitin-proteasome proteolytic pathway and may play a role in cancer cachexia.

  British journal of cancer 20050822

• Amylin induces natriuresis by a central angiotensin-dependent mechanism.

  Regulatory peptides 20050815

• The effect of angiotensin III on protein tyrosine kinase activity in rat pituitary.

  Regulatory peptides 20050815

• [The renin-angiotensin-aldosterone system -- more complex as previously thought].

  Medizinische Klinik (Munich, Germany : 1983) 20050815

• Role of interleukin-6 in cardiomyocyte/cardiac fibroblast interactions during myocyte hypertrophy and fibroblast proliferation.

  Journal of cellular physiology 20050801

• Angiotensin II dilates bovine adrenal cortical arterioles: role of endothelial nitric oxide.

  Endocrinology 20050801

• Tubular expression of angiotensin II receptors and their regulation in IgA nephropathy.

  Journal of the American Society of Nephrology : JASN 20050801

• Region-specific, pacing-induced changes in repolarization in rabbit atrium: an example of sensitivity to the rare.

  Cardiovascular research 20050801

• Functional evidence that in the cardiovascular system AT1 angiotensin II receptors are AT1B prejunctionally and AT1A postjunctionally.

  Cardiovascular research 20050801

• Brain ouabain stimulates peripheral marinobufagenin via angiotensin II signalling in NaCl-loaded Dahl-S rats.

  Journal of hypertension 20050801

• Infusion of angiotensin II reduces loss of glomerular capillary area in the early phase of anti-Thy-1.1 nephritis possibly via regulating angiogenesis-associated factors.

  Kidney international 20050801

• Oxygen consumption in the kidney: effects of nitric oxide synthase isoforms and angiotensin II.

  Kidney international 20050801

• Add-on and withdrawal effect of pravastatin on proteinuria in hypertensive patients treated with AT receptor blockers.

  Kidney international 20050801

• Comparison of the effect of enalapril and losartan in conjunction with surgical coronary revascularisation versus revascularisation alone on systemic endothelial function.

  Heart (British Cardiac Society) 20050801

• Blockade of endogenous angiotensin-(1-7) in the hypothalamic paraventricular nucleus reduces renal sympathetic tone.

  Hypertension (Dallas, Tex. : 1979) 20050801

• Pulse pressure and antihypertensive agents.

  Hypertension (Dallas, Tex. : 1979) 20050801

• Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach.

  Nature medicine 20050801

• Low-affinity state beta1-adrenoceptor-induced vasodilation in SHR.

  Peptides 20050801

• Effects of losartan and amlodipine on urinary albumin excretion and ambulatory blood pressure in hypertensive type 2 diabetic patients with overt nephropathy.

  Diabetes care 20050801

• Role of a responsive sympathetic nervous system in the chronic hypotensive effects of losartan in normal rats.

  Journal of cardiovascular pharmacology 20050801

• Losartan attenuates the antimigratory effect of diclofenac in spontaneously hypertensive rats.

  Journal of cardiovascular pharmacology 20050801

• Presynaptic angiotensin II AT1 receptors enhance inhibitory and excitatory synaptic neurotransmission to motoneurons and other ventral horn neurons in neonatal rat spinal cord.

  Journal of neurophysiology 20050801

• Effect of telmisartan on blood pressure control and kidney function in hypertensive, proteinuric patients with chronic kidney disease.

  Blood pressure monitoring 20050801

• Pollutant particles produce vasoconstriction and enhance MAPK signaling via angiotensin type I receptor.

  Environmental health perspectives 20050801

• Biphasic effects of losartan potassium on immobility in mice.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050801

• Efficacy and duration of action of the four selective angiotensin II subtype 1 receptor blockers, losartan, candesartan, valsartan and telmisartan, in patients with essential hypertension determined by home blood pressure measurements.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20050801

• Long-term combined therapy with losartan and an angiotensin-converting enzyme inhibitor improves functional capacity in patients with left ventricular dysfunction.

  Acta cardiologica 20050801

• [Severe hyperkalemia associated to the use of losartan and spironolactone: case report].

  Revista medica de Chile 20050801

• [Comparison of doxycycline, losartan, and their combination in the prevention of post-infarction remodeling in rats].

  Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20050801

• Ketobemidone is a substrate for cytochrome P4502C9 and 3A4, but not for P-glycoprotein.

  Xenobiotica; the fate of foreign compounds in biological systems 20050801

• Quality of life and antihypertensive effect with nebivolol and losartan.

  American journal of hypertension 20050801

• Resolution of hypertensive encephalopathy and scleroderma renal crisis with an angiotensin receptor blocker.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20050801

• Researched Medicines Industry (RMI) Code of Practice complaints 2004.

  The New Zealand medical journal 20050729

• Des-aspartate-angiotensin I and angiotensin AT1 receptors in rat cardiac ventricles.

  Regulatory peptides 20050715

• Modulation of the (Na(+)+K+)ATPase activity by Angiotensin-(1-7) in MDCK cells.

  Regulatory peptides 20050715

• Cholinergic stimulation in the lateral septal area activates anterior hypothalamic area neurons via excitatory amino acid receptors in rats.

  Brain research 20050712

• The scar neovasculature after myocardial infarction in rats.

  American journal of physiology. Heart and circulatory physiology 20050701

• Upregulation of beta-adrenergic receptors in heart failure due to volume overload.

  American journal of physiology. Heart and circulatory physiology 20050701

• AT1-receptor antagonism reverses the blood pressure elevation associated with diet-induced obesity.

  American journal of physiology. Regulatory, integrative and comparative physiology 20050701

• A potential role for angiotensin II in obesity induced cardiac hypertrophy and ischaemic/reperfusion injury.

  Basic research in cardiology 20050701

• Angiotensin depolarizes parvocellular neurons in paraventricular nucleus through modulation of putative nonselective cationic and potassium conductances.

  American journal of physiology. Regulatory, integrative and comparative physiology 20050701

• Comparative pharmacokinetics of two tablet formulations of Losartan: bioequivalence assessment.

  Biopharmaceutics & drug disposition 20050701

• Cost effectiveness of losartan in patients with hypertension and LVH: an economic evaluation for Sweden of the LIFE trial.

  Journal of hypertension 20050701

• Recurrent infarction causes the most deaths following myocardial infarction with left ventricular dysfunction.

  The American journal of medicine 20050701

• Arterial structural changes in rats immunized by AT1-receptor peptide.

  Heart and vessels 20050701

• Comparison of losartan and captopril on heart failure-related outcomes and symptoms from the losartan heart failure survival study (ELITE II).

  American heart journal 20050701

• Can losartan prevent new-onset atrial fibrillation in hypertensive patients more effectively than atenolol?

  Nature clinical practice. Cardiovascular medicine 20050701

• Telmisartan/Hydrochlorothiazide in comparison with losartan/hydrochlorothiazide in managing patients with mild-to-moderate hypertension.

  Hypertension research : official journal of the Japanese Society of Hypertension 20050701

• Significance of angiotensin II receptor blocker lipophilicities and their protective effect against vascular remodeling.

  Hypertension research : official journal of the Japanese Society of Hypertension 20050701

• Study of efficacy and safety of losartan (losar) in Asian Indian hypertensives.

  Journal of the Indian Medical Association 20050701

• Pericryptal myofibroblast growth in rat descending colon induced by low-sodium diets is mediated by aldosterone and not by angiotensin II.

  The Journal of membrane biology 20050701

• Losartan in cardiovascular disease.

  Future cardiology 20050701

• Protective effect of the inhibition of the renin-angiotensin system on aging.

  Regulatory peptides 20050630

• Pharmacophore, drug metabolism, and pharmacokinetics models on non-peptide AT1, AT2, and AT1/AT2 angiotensin II receptor antagonists.

  Journal of medicinal chemistry 20050630

• Angiotensin II subtype 1 receptor blockade inhibits Clostridium difficile toxin A-induced intestinal secretion in a rabbit model.

  The Journal of infectious diseases 20050615

• Combined effects of losartan and pravastatin on interstitial inflammation and fibrosis in chronic cyclosporine-induced nephropathy.

  Transplantation 20050615

• Angiotensin-converting enzyme inhibition and angiotensin AT1-receptor antagonism equally improve endothelial vasodilator function in L-NAME-induced hypertensive rats.

  European journal of pharmacology 20050615

• Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage.

  Circulation 20050614

• Central injection of hypertonic saline activates angiotensin II-sensitive neurons in the anterior hypothalamic area of rats.

  Brain research 20050607

• Letter regarding article by Devereux et al, 'regression of hypertensive left ventricular hypertrophy by losartan compared with atenolol: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial'.

  Circulation 20050607

• Angiotensin II attenuates synaptic GABA release and excites paraventricular-rostral ventrolateral medulla output neurons.

  The Journal of pharmacology and experimental therapeutics 20050601

• Modification of sarcolemmal Na+-K+-ATPase and Na+/Ca2+ exchanger expression in heart failure by blockade of renin-angiotensin system.

  American journal of physiology. Heart and circulatory physiology 20050601

• Endothelin isoforms and the response to myocardial stretch.

  American journal of physiology. Heart and circulatory physiology 20050601

• Insulin treatment enhances AT1 receptor function in OK cells.

  American journal of physiology. Renal physiology 20050601

• Soluble CD40 ligand in acute and chronic heart failure.

  European heart journal 20050601

• Suppressors of cytokine signaling regulate angiotensin II-activated Janus kinase-signal transducers and activators of transcription pathway in renal cells.

  Journal of the American Society of Nephrology : JASN 20050601

• Importance of baseline distribution of proteinuria in renal outcomes trials: lessons from the reduction of endpoints in NIDDM with the angiotensin II antagonist losartan (RENAAL) study.

  Journal of the American Society of Nephrology : JASN 20050601

• Angiotensin II type 1 receptor inhibition markedly improves the blood perfusion, oxygen tension and first phase of glucose-stimulated insulin secretion in revascularised syngeneic mouse islet grafts.

  Diabetologia 20050601

• ATR blockade reduces IFN-gamma production in lymphocytes in vivo and in vitro.

  Kidney international 20050601

• Reduction of urinary connective tissue growth factor by Losartan in type 1 patients with diabetic nephropathy.

  Kidney international 20050601

• Augmented input from cardiac sympathetic afferents inhibits baroreflex in rats with heart failure.

  Hypertension (Dallas, Tex. : 1979) 20050601

• Vascular, hemodynamic and renal effects of low-dose losartan in rats with secondary biliary cirrhosis.

  Liver international : official journal of the International Association for the Study of the Liver 20050601

• [Treatment of hypertension in elderly patients with coronary heart disease].

  Nihon rinsho. Japanese journal of clinical medicine 20050601

• Learning from large cardiovascular clinical trials: classical cardiovascular risk factors.

  Diabetes research and clinical practice 20050601

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• Anemia due to losartan in hypertensive renal transplant recipients without posttransplant erythrocytosis.

  Transplantation proceedings 20050601

• Angiotensin II enhances thrombosis development in renovascular hypertensive rats.

  Thrombosis and haemostasis 20050601

• [Progress on the drug therapy for diabetic microangiopathies: RA system inhibitor].

  Nihon rinsho. Japanese journal of clinical medicine 20050601

• Multiple actions of halothane on contractile response to noradrenaline in isolated mesenteric resistance arteries.

  Naunyn-Schmiedeberg's archives of pharmacology 20050601

• Clinical update: the role of angiotensin II receptor blockers in patients with left ventricular dysfunction (Part II of II).

  Clinical cardiology 20050601

• [P38 MAPK was involved in angiotensin-induced migratory potential of adventitial fibroblasts from spontaneously hypertensive rat].

  Zhonghua xin xue guan bing za zhi 20050601

• Antiproliferative action of an angiotensin I-converting enzyme inhibitory peptide, Val-Tyr, via an L-type Ca2+ channel inhibition in cultured vascular smooth muscle cells.

  Hypertension research : official journal of the Japanese Society of Hypertension 20050601

• A review of studies of adherence with antihypertensive drugs using prescription databases.

  Therapeutics and clinical risk management 20050601

• Angiotensin II protects cultured midbrain dopaminergic neurons against rotenone-induced cell death.

  Brain research 20050531

• Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2.

  Circulation 20050524

• [Uric acid--more deleterious than we thought?].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20050519

• Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-beta-independent mechanism.

  Circulation 20050517

• Effects of angiotensin II type 1 receptor blockade on the oxidative stress in spontaneously hypertensive rat tissues.

  Regulatory peptides 20050515

• Advanced glycation end-product-induced mitogenesis and collagen production are dependent on angiotensin II and connective tissue growth factor in NRK-49F cells.

  Journal of cellular biochemistry 20050515

• [Utilizing progress in modern antihypertensive therapy. Treating hypertension effectively from the beginning].

  MMW Fortschritte der Medizin 20050512

• [A suitable antihypertensive drug of significance. Protection of heart, brain and kidney is decisive].

  MMW Fortschritte der Medizin 20050512

• Angiotensin II blocks memory consolidation through an AT2 receptor-dependent mechanism.

  Psychopharmacology 20050501

• Sympathoexcitation by central ANG II: roles for AT1 receptor upregulation and NAD(P)H oxidase in RVLM.

  American journal of physiology. Heart and circulatory physiology 20050501

• Cardiac myocytes control release of endothelin-1 in coronary vasculature.

  American journal of physiology. Heart and circulatory physiology 20050501

• Polymorphism in angiotensin II receptor genes and hypertension.

  Experimental physiology 20050501

• Angiotensin II enhances insulin sensitivity in vitro and in vivo.

  Endocrinology 20050501

• Sympathetic modulation by carvedilol and losartan reduces angiotensin II-mediated lipolysis in subcutaneous and visceral fat.

  The Journal of clinical endocrinology and metabolism 20050501

• High-salt diet inhibits expression of angiotensin type 2 receptor in resistance arteries.

  Hypertension (Dallas, Tex. : 1979) 20050501

• Potentiation of L-NAME-induced systemic and renal vasoconstrictor responses by alpha1-adrenoceptor antagonism.

  Journal of hypertension 20050501

• Opposite effects of losartan and atenolol on natriuretic peptides in patients with hypertension and left ventricular hypertrophy: a LIFE substudy.

  Journal of hypertension 20050501

• An extremely high dose of losartan affords superior renoprotection in the remnant model.

  Kidney international 20050501

• Keeping tabs on your heart while treating BP.

  The Johns Hopkins medical letter health after 50 20050501

• Losartan blocks the excitatory effect of peripheral hypertonic stimulation on vasopressinergic neurons in hypothalamic paraventricular nucleus in rats: electrophysiological and immunocytochemical evidence.

  Neuroscience letters 20050501

• A review of the current evidence for the use of angiotensin-receptor blockers in chronic heart failure.

  International journal of clinical practice 20050501

• Low doses of losartan and trandolapril improve arterial stiffness in hemodialysis patients.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20050501

• Late recurrence of scleroderma renal crisis in a renal transplant recipient despite angiotensin II blockade.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20050501

• Persistent effects on blood pressure and renal function of perindopril alone or combined with losartan in Lyon hypertensive rats.

  American journal of hypertension 20050501

• Hypertension, antihypertensive treatment and stroke prevention.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20050501

• Cardiomyopathy associated with celiac disease.

  Mayo Clinic proceedings 20050501

• [Protective effects of losartan against myocardial ischemic reperfusion in intact canine].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050501

• Long-term inhibition of angiotensin prevents reduction of periarterial innervation of calcitonin gene-related peptide (CGRP)-containing nerves in spontaneously hypertensive rats.

  Hypertension research : official journal of the Japanese Society of Hypertension 20050501

• Does losartan reduce the risk of stroke in patients with hypertension?

  Nature clinical practice. Cardiovascular medicine 20050501

• Signaling pathways in the biphasic effect of ANG II on Na+/H+ exchanger in T84 cells.

  The Journal of membrane biology 20050501

• [Effect of Ang II on PDGF receptor expression in vascular smooth muscle cell].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20050501

• Angiotensin II inhibition during myocardial ischemia-reperfusion in dogs: effects on leukocyte infiltration, nitric oxide synthase isoenzymes activity and left ventricular ejection fraction.

  International journal of cardiology 20050428

• Body build and risk of cardiovascular events in hypertension and left ventricular hypertrophy: the LIFE (Losartan Intervention For Endpoint reduction in hypertension) study.

  Circulation 20050419

• Upregulation of angiotensin II type 1 receptor, inflammatory mediators, and enzymes of arachidonate metabolism in obese Zucker rat kidney: reversal by angiotensin II type 1 receptor blockade.

  Circulation 20050419

• Pharmacological concentration of angiotensin-(1-7) activates NADPH oxidase after ischemia-reperfusion in rat heart through AT1 receptor stimulation.

  Regulatory peptides 20050415

• Intracisternal galanin/angiotensin II interactions in central cardiovascular control.

  Regulatory peptides 20050415

• Protein kinase C-mediated inhibition of renal Ca2+ ATPase by physiological concentrations of angiotensin II is reversed by AT1- and AT2-receptor antagonists.

  Regulatory peptides 20050415

• Blockage of angiotensin II type I receptor decreases the synthesis of growth factors and induces apoptosis in C6 cultured cells and C6 rat glioma.

  British journal of cancer 20050411

• Cardiovascular effects of angiotensin II and angiotensin-(1-7) at the RVLM of trained normotensive rats.

  Brain research 20050408

• Angiogenic protection from focal ischemia with angiotensin II type 1 receptor blockade in the rat.

  American journal of physiology. Heart and circulatory physiology 20050401

• Effects of pre-, peri-, and postmyocardial infarction treatment with losartan in rats: effect of dose on survival, ventricular arrhythmias, function, and remodeling.

  American journal of physiology. Heart and circulatory physiology 20050401

• Central angiotensin II AT1 receptors mediate fetal swallowing and pressor responses in the near-term ovine fetus.

  American journal of physiology. Regulatory, integrative and comparative physiology 20050401

• Sarcoplasmic reticulum Ca2+ transport and gene expression in congestive heart failure are modified by imidapril treatment.

  American journal of physiology. Heart and circulatory physiology 20050401

• Administration of ANG II induces iron deposition and upregulation of TGF-beta1 mRNA in the rat liver.

  American journal of physiology. Regulatory, integrative and comparative physiology 20050401

• Markers of collagen synthesis is related to blood pressure and vascular hypertrophy: a LIFE substudy.

  Journal of human hypertension 20050401

• Effect of losartan and spironolactone on left ventricular mass and heart sympathetic activity in prehypertensive obese subjects: a 16-week randomized trial.

  Journal of human hypertension 20050401

• B1 kinin receptor does not contribute to vascular tone or tissue plasminogen activator release in the peripheral circulation of patients with heart failure.

  Arteriosclerosis, thrombosis, and vascular biology 20050401

• Interaction of angiotensin II type 1 and D5 dopamine receptors in renal proximal tubule cells.

  Hypertension (Dallas, Tex. : 1979) 20050401

• Angiotensin II receptor inhibition prevents pneumocyte apoptosis in surfactant-depleted rat lungs.

  Pediatric pulmonology 20050401

• Angiotensin II and aldosterone regulate gene transcription via functional mineralocortocoid receptors in human coronary artery smooth muscle cells.

  Circulation research 20050401

• Role of the renin-angiotensin system on the parathyroid hormone-related protein overexpression induced by nephrotoxic acute renal failure in the rat.

  Journal of the American Society of Nephrology : JASN 20050401

• Persistent sympathetic activation during chronic antihypertensive therapy: a potential mechanism for long term morbidity?

  Hypertension (Dallas, Tex. : 1979) 20050401

• NAD(P)H oxidase inhibition attenuates neuronal chronotropic actions of angiotensin II.

  Circulation research 20050401

• Renoprotection with and without blood pressure reduction.

  Kidney international. Supplement 20050401

• Genetic contribution to the acute effects of angiotensin II type 1 receptor blockade.

  Journal of hypertension 20050401

• Long-term treatment with losartan versus atenolol improves insulin sensitivity in hypertension: ICARUS, a LIFE substudy.

  Journal of hypertension 20050401

• Pulse pressure and effects of losartan or atenolol in patients with hypertension and left ventricular hypertrophy.

  Hypertension (Dallas, Tex. : 1979) 20050401

• Loss of heparan N-sulfotransferase in diabetic liver: role of angiotensin II.

  Diabetes 20050401

• Randomized, controlled study of the effects of losartan versus enalapril in small doses on proteinuria and tubular injury in primary glomerulonephritis.

  Medical science monitor : international medical journal of experimental and clinical research 20050401

• Angiotensin II antagonism fails to ameliorate bleomycin-induced pulmonary fibrosis in mice.

  The European respiratory journal 20050401

• The expression of messenger RNA for ADP-ribosyl cyclase in aldosterone-producing adenomas.

  Clinical endocrinology 20050401

• Differential effects of angiotensin II on atherogenesis at the aortic sinus and descending aorta of apolipoprotein-E-deficient mice.

  American journal of hypertension 20050401

• Angiotensin II type 2 receptors contribute to vascular responses in spontaneously hypertensive rats treated with angiotensin II type 1 receptor antagonists.

  American journal of hypertension 20050401

• [Effects of captopril and losartan on expression of kidney aquaporin-2 mRNA and urine aquaporin-2 excretion in rats].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050401

• Plasmapheresis for the prophylaxis and treatment of recurrent focal segmental glomerulosclerosis following renal transplant.

  Transplantation proceedings 20050401

• [Blockade of renin-angiotensin system attenuates cardiac remodeling in rats undergoing aortic stenosis].

  Arquivos brasileiros de cardiologia 20050401

• [Effect of danshensu and ligustrazine on related genes of myocardial hypertrophy induced by angiotensin II].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20050401

• Enlarged hearts, larger threats. But reducing heart-muscle mass can blunt cardiac dangers.

  Heart advisor 20050401

• Protective effects of blocking renin-angiotensin system on the progression of renal injury in glomerulosclerosis.

  Cellular & molecular immunology 20050401

• Interaction of central Ang II and NO on the cardiac sympathetic afferent reflex in dogs.

  Autonomic neuroscience : basic & clinical 20050331

• Stability study of losartan/hydrochlorothiazide tablets.

  International journal of pharmaceutics 20050303

• Role of angiotensin in body fluid homeostasis of mice: effect of losartan on water and NaCl intakes.

  American journal of physiology. Regulatory, integrative and comparative physiology 20050301

• Blood pressure maintenance in NHE3-deficient mice with transgenic expression of NHE3 in small intestine.

  American journal of physiology. Regulatory, integrative and comparative physiology 20050301

• The effect of an angiotensin-converting enzyme inhibitor and a K+(ATP) channel opener on warm up angina.

  European heart journal 20050301

• Evidence for a functional cardiac interaction between losartan and angiotensin-(1-7) receptors revealed by orthostatic tilting test in rats.

  British journal of pharmacology 20050301

• Valsartan in chronic heart failure.

  The Annals of pharmacotherapy 20050301

• Amelioration of 2,4,6-trinitrobenzene sulphonic acid induced colitis in angiotensinogen gene knockout mice.

  Gut 20050301

• Transforming growth factor beta1 and additional renoprotective effect of combination ACE inhibitor and angiotensin II receptor blocker in hypertensive subjects with minor renal abnormalities: a 24-week randomized controlled trial.

  Journal of hypertension 20050301

• The renin-angiotensin system and the developing retinal vasculature.

  Investigative ophthalmology & visual science 20050301

• Cardiovascular morbidity and mortality in hypertensive patients with a history of atrial fibrillation: The Losartan Intervention For End Point Reduction in Hypertension (LIFE) study.

  Journal of the American College of Cardiology 20050301

• Angiotensin II receptor blockade reduces new-onset atrial fibrillation and subsequent stroke compared to atenolol: the Losartan Intervention For End Point Reduction in Hypertension (LIFE) study.

  Journal of the American College of Cardiology 20050301

• Angiotensin II inhibition and prevention of atrial fibrillation and stroke.

  Journal of the American College of Cardiology 20050301

• A1166C angiotensin II type 1 receptor gene polymorphism may predict hemodynamic response to losartan in patients with cirrhosis and portal hypertension.

  The American journal of gastroenterology 20050301

• Angiotensin II, angiotensin II antagonists and spironolactone and their modulation of cardiac repolarization.

  Trends in pharmacological sciences 20050301

• The effects of losartan compared to atenolol on stroke in patients with isolated systolic hypertension and left ventricular hypertrophy. The LIFE study.

  Journal of clinical hypertension (Greenwich, Conn.) 20050301

• Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human mesangial cells and induce interleukin-6 and plasminogen activator inhibitor-1 secretion.

  American journal of hypertension 20050301

• The effect of losartan and losartan/hydrochlorothiazide fixed-combination on magnesium, zinc, and nitric oxide metabolism in hypertensive patients: a prospective open-label study.

  American journal of hypertension 20050301

• Comparison of 3 AT1 receptor binding assays: filtration assay, ScreenReady Target, and WGA Flashplate.

  Journal of biomolecular screening 20050301

• Losartan and end-organ protection--lessons from the RENAAL study.

  Clinical cardiology 20050301

• Effect of losartan and enalapril on cognitive deficit caused by Goldblatt induced hypertension.

  Indian journal of experimental biology 20050301

• Editorial overview: The 'sartans': is it premature to consider PPARgamma receptor agonism a bonus?

  Current opinion in investigational drugs (London, England : 2000) 20050301

• Progress in the development of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers.

  Current opinion in investigational drugs (London, England : 2000) 20050301

• Morphological changes in experimental postischemic rat kidney. A pilot study.

  Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 20050301

• Renoprotective effect of early inhibition of the renin-angiotensin system in renal transplant recipients.

  Transplantation proceedings 20050301

• Inhibition of plasminogen activator inhibitor-1 by angiotensin II receptor blockers on cyclosporine-treated renal allograft recipients.

  Transplantation proceedings 20050301

• [Therapeutic interchange standardization for antiotensin II receptor antagonists in the treatment of hypertension in the hospital setting].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20050301

• Molecular-specific effects of angiotensin II antagonists: clinical relevance to treating hypertension?

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20050301

• [Effects of angiotensin II and aldosterone on NF-kappaB binding activity in hepatic stellate cells].

  Zhonghua yi xue za zhi 20050216

• [Comparative study of effects of fluvastatin and losartan on left ventricular remodeling in rat myocardial infarction].

  Zhonghua yi xue za zhi 20050216

• Cardiac gene expression profile in rats with terminal heart failure and cachexia.

  Physiological genomics 20050210

• Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection.

  The New England journal of medicine 20050210

• [Ace inhibitors and angiotensin II receptor antagonists for therapy of chronic heart failure].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20050210

• The medial amygdaloid area is involved in activation of angiotensin II-sensitive neurons in the anterior hypothalamic area.

  Brain research 20050208

• Angiotensin II inhibition of Ca2+ currents is independent of ATR1 angiotensin II receptor activation in rat adult vagal afferent neurons.

  Autonomic neuroscience : basic & clinical 20050207

• Treatment of systolic hypertension: spotlight on recent studies with angiotensin II antagonists.

  Journal of human hypertension 20050201

• Salt-induced ANG II suppression impairs the response of cerebral artery smooth muscle cells to prostacyclin.

  American journal of physiology. Heart and circulatory physiology 20050201

• Influence of growth factors on the proliferation of vascular smooth muscle cells isolated from subtotally nephrectomized rats after endothelin or angiotensin II antagonism.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050201

• Prognostic risk of atrial fibrillation in acute myocardial infarction complicated by left ventricular dysfunction: the OPTIMAAL experience.

  European heart journal 20050201

• Hemodynamic and metabolic effects of angiotensin II on the liver.

  Peptides 20050201

• Modulatory role of the adventitia on noradrenaline and angiotensin II responses role of endothelium and AT2 receptors.

  Cardiovascular research 20050201

• Mechanisms underlying the endothelium-independent relaxation induced by angiotensin II in rat aorta.

  Journal of cardiovascular pharmacology 20050201

• Poor prognosis in proteinuric type 2 diabetic patients with retinopathy: insights from the RENAAL study.

  QJM : monthly journal of the Association of Physicians 20050201

• Angiotensin II type-1 receptor antagonism attenuates the inflammatory and thrombogenic responses to hypercholesterolemia in venules.

  Hypertension (Dallas, Tex. : 1979) 20050201

• Reduction in albuminuria translates to reduction in cardiovascular events in hypertensive patients: losartan intervention for endpoint reduction in hypertension study.

  Hypertension (Dallas, Tex. : 1979) 20050201

• Effect of insulin and angiotensin II receptor subtype-1 antagonist on myocardial remodelling in rats with insulin-dependent diabetes mellitus.

  Journal of hypertension 20050201

• Angiotensin II receptor antagonist treatment during pregnancy.

  Birth defects research. Part A, Clinical and molecular teratology 20050201

• Functional interaction of AT1 and AT2 receptors in fructose-induced insulin resistance and hypertension in rats.

  Metabolism: clinical and experimental 20050201

• Pulmonary hypertension during epileptic seizure with evidence of increased angiotensin II in pulmonary artery.

  Heart and vessels 20050201

• Case-based study: from prediabetes to complications--opportunities for prevention.

  PLoS medicine 20050201

• Adult hypertension: reducing cardiovascular morbidity and mortality.

  Prescrire international 20050201

• A double-blind, dose-response study of losartan in hypertensive children.

  American journal of hypertension 20050201

• Role of angiotensin receptor blockers as monotherapy in reaching blood pressure goals.

  American journal of hypertension 20050201

• [Treatment of hypertensive patients with impaired glucose tolerance (IGT)].

  Nihon rinsho. Japanese journal of clinical medicine 20050201

• [Comparison of doxycycline, losartan, and their combination on the expression of matrix metalloproteinase, tissue inhibitor of matrix metalloproteinase, and collagen remodeling in the noninfarcted myocardium after acute myocardial infarction in rats].

  Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20050201

• Redefining efficacy of antihypertensive therapies beyond blood pressure reduction--the role of angiotensin II antagonists.

  International journal of clinical practice 20050201

• [Changes of serum asymmetric dimethylarginine in essential hypertension before and after the treatment].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20050201

• Losartan increases bradykinin levels in hypertensive humans.

  Circulation 20050125

• Attentuation of cardiac stunning by losartan in a cellular model of ischemia and reperfusion is accompanied by increased sarcoplasmic reticulum Ca2+ stores and prevention of cytosolic Ca2+ elevation.

  The Journal of pharmacology and experimental therapeutics 20050101

• Regional hemodynamic actions of selective corticotropin-releasing factor type 2 receptor ligands in conscious rats.

  The Journal of pharmacology and experimental therapeutics 20050101

• Profibrotic influence of high glucose concentration on cardiac fibroblast functions: effects of losartan and vitamin E.

  American journal of physiology. Heart and circulatory physiology 20050101

• Angiotensin II-dependent induction of AT(2) receptor expression after renal ablation.

  American journal of physiology. Renal physiology 20050101

• Angiotensin II receptor modulation of renal vascular resistance and neurotransmission in young and adult spontaneously hypertensive rats.

  Kidney & blood pressure research 20050101

• Stroke reduction in hypertensive adults with cardiac hypertrophy randomized to losartan versus atenolol: the Losartan Intervention For Endpoint reduction in hypertension study.

  Hypertension (Dallas, Tex. : 1979) 20050101

• Uric acid elimination in the urine. Pathophysiological implications.

  Contributions to nephrology 20050101

• Restoration of erectile capacity in normotensive aged rats by modulation of angiotensin receptor type 1.

  Journal of andrology 20050101

• Inhibition of catecholamine-induced cardiac fibrosis by an aldosterone antagonist.

  Journal of cardiovascular pharmacology 20050101

• Effect of losartan on muscle sympathetic activity and baroreceptor function in systemic hypertension.

  The American journal of cardiology 20050101

• Fixed-dose combinations in the management of hypertension: defining the place of angiotensin receptor antagonists and hydrochlorothiazide.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101

• Use of 24-hour ambulatory blood pressure monitoring to assess antihypertensive efficacy: a comparison of olmesartan medoxomil, losartan potassium, valsartan, and irbesartan.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101

• Blockade of angiotensin II with losartan attenuates transforming growth factor-beta1 inducible gene-h3 (betaig-h3) expression in a model of chronic cyclosporine nephrotoxicity.

  Nephron. Experimental nephrology 20050101

• Left ventricular hypertrophy and angiotensin II receptor blocking agents.

  Current medicinal chemistry. Cardiovascular and hematological agents 20050101

• Angiotensin II-mediated calcium signals and mitogenesis in human prostate stromal cell line hPCPs.

  British journal of pharmacology 20050101

• Crosstalk between mesangial and endothelial cells: angiotensin II down-regulates endothelin-converting enzyme 1.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101

• Imidapril treatment improves the attenuated inotropic and intracellular calcium responses to ATP in heart failure due to myocardial infarction.

  British journal of pharmacology 20050101

• Blood flow measurements in rats using four color microspheres during blockade of different vasopressor systems.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20050101

• Chemopreventive effect of five drugs on renal interstitial fibrosis induced by an aristolochic acid-containing Chinese herb in rats.

  American journal of nephrology 20050101

• Of the renin-angiotensin system and reactive oxygen species Type 2 diabetes and angiotensin II inhibition.

  American journal of hypertension 20050101

• H-ATPase activity in collecting duct segments in protein-deprived rats - role of angiotensin II on its regulation.

  Nephron. Physiology 20050101

• Preventing type 2 diabetes mellitus.

  The Journal of the American Board of Family Practice 20050101

• A meta-analytical approach to the efficacy of antihypertensive drugs in reducing blood pressure.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101

• ATRA therapy restores normal renal function and renal reserve and prevents renal failure.

  Annals of the Academy of Medicine, Singapore 20050101

• Comparison of the effects of quinapril and losartan on carotid artery intima-media thickness in patients with mild-to-moderate arterial hypertension.

  Kidney & blood pressure research 20050101

• Effect of high glucose on superoxide in human mesangial cells: role of angiotensin II.

  Nephron. Experimental nephrology 20050101

• Angiotensin II mediates high glucose-induced TGF-beta1 and fibronectin upregulation in HPMC through reactive oxygen species.

  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20050101

• Effects of the early administration of losartan on the functional and morphological aspects of postmyocardial infarction ventricular remodeling in rabbits.

  Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 20050101

• [Effect of losartan on heme oxygenase-1 expression in volume overloaded rats].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20050101

• A new role for the renin-angiotensin system in the rat periaqueductal gray matter: angiotensin receptor-mediated modulation of nociception.

  Neuroscience 20050101

• Portopulmonary hypertension in a patient of autoimmune hepatitis.

  The Indian journal of chest diseases & allied sciences 20050101

• [Myocardial remodeling after experimental acute myocardial infarction in rats. Effect of renin-angiotensin-aldosterone blockade].

  Arquivos brasileiros de cardiologia 20050101

• Chronic effects of angiotensin II and at1 receptor antagonists in subfornical organ-lesioned rats.

  Clinical and experimental pharmacology & physiology 20050101

• Telmisartan has the strongest binding affinity to angiotensin II type 1 receptor: comparison with other angiotensin II type 1 receptor blockers.

  International journal of clinical pharmacology research 20050101

• Antiproteinuric effect of ARB in lupus nephritis patients with persistent proteinuria despite immunosuppressive therapy.

  Lupus 20050101

• Metabolic effect of telmisartan and losartan in hypertensive patients with metabolic syndrome.

  Cardiovascular diabetology 20050101

• Cold hands--strained heart? Advances in the management of Raynaud's phenomenon and pulmonary hypertension.

  Arthritis research & therapy 20050101

• Angiotensin II receptor antagonists alone and combined with hydrochlorothiazide: potential benefits beyond the antihypertensive effect.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101

• Blood pressure-independent ETA and AT1 receptor blocker effects on the coronaries of rats harboring human renin and angiotensinogen genes.

  Kidney & blood pressure research 20050101

• Kidney disease as CVD risk factor: implications for therapy.

  Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20050101

• The endothelium--'man of the match in the cardiovascular stakes'.

  Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20050101

• Linear regression analysis and its application to multivariate chromatographic calibration for the quantitative analysis of two-component mixtures.

  Farmaco (Societa chimica italiana : 1989) 20050101

• Determinants of persistence in hypertensive patients treated with irbesartan: results of a postmarketing survey.

  BMC cardiovascular disorders 20050101

• Echocardiography-based left ventricular mass estimation. How should we define hypertrophy?

  Cardiovascular ultrasound 20050101

• Hemodynamic influences of losartan on the brain in hypertensive patients.

  Hypertension research : official journal of the Japanese Society of Hypertension 20050101

• Different effects on inhibition of cardiac hypertrophy in spontaneously hypertensive rats by monotherapy and combination therapy of adrenergic receptor antagonists and/or the angiotensin II type 1 receptor blocker under comparable blood pressure reduction.

  Hypertension research : official journal of the Japanese Society of Hypertension 20050101

• Divergent regulation of circulating and intrarenal renin-angiotensin systems in response to long-term blockade.

  American journal of nephrology 20050101

• Progression of kidney disease in type 2 diabetes - beyond blood pressure control: an observational study.

  BMC nephrology 20050101

• L-NAME induces direct arteriolar leukocyte adhesion, which is mainly mediated by angiotensin-II.

  Microcirculation (New York, N.Y. : 1994) 20050101

• Do angiotensin II antagonists provide benefits beyond blood pressure reduction?

  Advances in therapy 20050101

• Clinical pharmacokinetics of losartan.

  Clinical pharmacokinetics 20050101

• Losartan but not atenolol reduce carotid artery hypertrophy in essential hypertension. A LIFE substudy.

  Blood pressure 20050101

• [Renin-angiotensin system in diabetic nephropathy].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20050101

• Effects of combined endothelin and angiotensin II antagonism on growth factor-induced proliferation of vascular smooth muscle cells isolated from uremic rats.

  Renal failure 20050101

• Pilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary disease.

  Respiratory research 20050101

• Losartan controlled blood pressure and reduced left ventricular hypertrophy but did not alter arrhythmias in hypertensive men with preserved systolic function.

  Angiology 20050101

• Angiotensin II stimulates matrix metalloproteinase secretion in human vascular smooth muscle cells via nuclear factor-kappaB and activator protein 1 in a redox-sensitive manner.

  Journal of vascular research 20050101

• Long-term blood pressure control prevents oxidative renal injury.

  Antioxidants & redox signaling 20050101

• [Use of lozartan in patients with chronic cor pulmonale].

  Klinicheskaia meditsina 20050101

• Histopathological and ultrastructural effects of Losartan on embryonic rat kidney.

  Acta histochemica 20050101

• The impact of losartan on the lifetime incidence of ESRD and costs in Mexico.

  Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20050101

• Sustained white cell cytokine activation in idiopathic dilated cardiomyopathy despite haemodynamic improvement with medical therapy.

  Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20050101

• Angiotensin receptor blockers in congestive heart failure: evidence, concerns, and controversies.

  Cardiology in review 20050101

• [Pharmacogenetics of angiotensin system in non diabetic nephropathy].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20050101

• [A new approach to treating secondary pulmonary hypertension].

  Problemy tuberkuleza i boleznei legkikh 20050101

• A rapid HPLC method for the determination of losartan in human plasma using a monolithic column.

  Arzneimittel-Forschung 20050101

• Low-dose dual blockade of the renin-angiotensin system improves tubular status in non-diabetic proteinuric patients.

  Scandinavian journal of urology and nephrology 20050101

• Flecainide overdose--support using an intra-aortic balloon pump.

  BMC emergency medicine 20050101

• Ambulatory blood pressure comparison of the anti-hypertensive efficacy of fixed combinations of irbesartan/hydrochlorothiazide and losartan/hydrochlorothiazide in patients with mild-to-moderate hypertension.

  The Journal of international medical research 20050101

• Effect on serum uric acid levels of drugs prescribed for indications other than treating hyperuricaemia.

  Current pharmaceutical design 20050101

• Gout in solid organ transplantation: a challenging clinical problem.

  Drugs 20050101

• Losartan: a review of its use in stroke risk reduction in patients with hypertension and left ventricular hypertrophy.

  Drugs 20050101

• [Beneficial effects of combination therapy with losartan and low-dose hydrochlorothiazide in the treatment of essential hypertension].

  Nihon Jinzo Gakkai shi 20050101

• Effect of systemic insulin and angiotensin II receptor subtype-1 antagonist on endothelin-1 receptor subtype(s) regulation and binding in diabetic rat heart.

  Endothelium : journal of endothelial cell research 20050101

• Effect of oral administration of losartan, prazosin, and verapamil on peritoneal solute transport in continuous ambulatory peritoneal dialysis patients.

  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20050101

• Renal vascular responses in an experimental model of preeclampsia.

  Proceedings of the Western Pharmacology Society 20050101

• Angiotensin inhibition or blockade for the treatment of patients with quiescent lupus nephritis and persistent proteinuria.

  Lupus 20050101

• Effect of losartan on the mRNA expressions of MT3-MMP and TIMP-2 in diabetic kidneys.

  The review of diabetic studies : RDS 20050101

• Efficacy and Safety of Olmesartan in the Treatment of Mild-to-Moderate Essential Hypertension in Chinese Patients.

  Clinical drug investigation 20050101

• Aliskiren in hypertension: evidence for its potential therapeutic value.

  Core evidence 20050101

• Chronic cyclosporine nephrotoxicity: new insights and preventive strategies.

  Yonsei medical journal 20041231

• Serotonergic mechanism of the lateral parabrachial nucleus and relaxin-induced sodium intake.

  Brain research 20041224

• Oxidative stress in the infarcted heart: role of de novo angiotensin II production.

  Biochemical and biophysical research communications 20041217

• [A problem that should be recognized. Greater risk of diabetes with antihypertensive drugs?].

  MMW Fortschritte der Medizin 20041216

• Additive beneficial effects of losartan combined with simvastatin in the treatment of hypercholesterolemic, hypertensive patients.

  Circulation 20041214

• ACE inhibition lowers angiotensin II-induced chemokine expression by reduction of NF-kappaB activity and AT1 receptor expression.

  Biochemical and biophysical research communications 20041210

• Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II.

  Circulation research 20041210

• [Changes of collagen expression of pulmonary arteries and heart ventricles and intervention of fosinopril and losartan in rats with heart failure].

  Zhonghua yi xue za zhi 20041202

• Central Tempol alters basal sympathetic nerve discharge and attenuates sympathetic excitation to central ANG II.

  American journal of physiology. Heart and circulatory physiology 20041201

• Effect of endogenous angiotensin II on the frequency response of the renal vasculature.

  American journal of physiology. Renal physiology 20041201

• Contribution of angiotensin II to alcohol-induced pancreatic fibrosis in rats.

  The Journal of pharmacology and experimental therapeutics 20041201

• Down-regulation of inositol 1,4,5-trisphosphate receptor in cells stably expressing the constitutively active angiotensin II N111G-AT(1) receptor.

  Molecular endocrinology (Baltimore, Md.) 20041201

• Disparate systemic and renal blocking properties of angiotensin II antagonists during exogenous angiotensin II administration: implications for treatment.

  Journal of human hypertension 20041201

• Multiple pheochromocytomas and paragangliomas in a young patient carrying a SDHD gene mutation.

  European journal of pediatrics 20041201

• Pharmacotherapy for diabetic retinopathy.

  Current opinion in ophthalmology 20041201

• Upregulation of lectinlike oxidized low-density lipoprotein receptor-1 expression contributes to the vein graft atherosclerosis: modulation by losartan.

  Atherosclerosis 20041201

• The use of angiotensin receptor blockers in the treatment of chronic heart failure.

  Journal of cardiovascular pharmacology 20041201

• Diverse effects of Ace inhibitors and angiotensin II receptor antagonists on prevention of cardiac hypertrophy and collagen distribution in spontaneously hypertensive rats.

  International journal of cardiology 20041201

• Angiotensin II stimulates Pax-2 in rat kidney proximal tubular cells: impact on proliferation and apoptosis.

  Kidney international 20041201

• Eplerenone in hypertension.

  Expert opinion on pharmacotherapy 20041201

• Continuum of renoprotection with losartan at all stages of type 2 diabetic nephropathy: a post hoc analysis of the RENAAL trial results.

  Journal of the American Society of Nephrology : JASN 20041201

• Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells.

  The Journal of endocrinology 20041201

• Drug interactions with the potential to prevent prodrug activation as a common source of irrational prescribing in hospital inpatients.

  Clinical pharmacology and therapeutics 20041201

• Different effects of losartan and moxonidine on endothelial function during sympathetic activation in essential hypertension.

  Journal of clinical hypertension (Greenwich, Conn.) 20041201

• [Effects of losartan on MT3-MMP and TIMP2 mRNA expressions in diabetic rat kidney].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20041201

• Aldosterone upregulates connective tissue growth factor gene expression via p38 MAPK pathway and mineralocorticoid receptor in ventricular myocytes.

  Journal of Korean medical science 20041201

• Comparison of different therapeutic strategies in hypertension: a low-dose combination of perindopril/indapamide versus a sequential monotherapy or a stepped-care approach.

  Journal of hypertension 20041201

• A double-blind ambulatory blood pressure monitoring study of the efficacy and tolerability of once-daily telmisartan 40 mg in comparison with losartan 50 mg in the treatment of mild-to-moderate hypertension in Taiwanese patients.

  International journal of clinical practice. Supplement 20041201

• A double-blind comparison of the efficacy and tolerability of telmisartan 40-80 mg vs. losartan 50-100 mg in Taiwanese hypertensive patients.

  International journal of clinical practice. Supplement 20041201

• Efficacy and safety of telmisartan vs. losartan in control of mild-to-moderate hypertension: a multicentre, randomised, double-blind study.

  International journal of clinical practice. Supplement 20041201

• Renin-angiotensin system inhibition prevents type 2 diabetes mellitus. Part 1. A meta-analysis of randomised clinical trials.

  Diabetes & metabolism 20041201

• Use of losartan in diabetic patients in the primary care setting: review of the results in LIFE and RENAAL.

  Current medical research and opinion 20041201

• Angiotensin II stimulates arachidonic acid release from bone marrow stromal cells.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20041201

• Losartan and simvastatin inhibit platelet activation in hypertensive patients.

  Journal of thrombosis and thrombolysis 20041201

• Diabetic nephropathy.

  Clinical evidence 20041201

• Low-dose combination therapy with temocapril and losartan reduces proteinuria in normotensive patients with immunoglobulin a nephropathy.

  Hypertension research : official journal of the Japanese Society of Hypertension 20041201

• Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist.

  Journal of medicinal chemistry 20041118

• AT2-selective angiotensin II analogues containing tyrosine-functionalized 5,5-bicyclic thiazabicycloalkane dipeptide mimetics.

  Journal of medicinal chemistry 20041118

• Regression of electrocardiographic left ventricular hypertrophy during antihypertensive treatment and the prediction of major cardiovascular events.

  JAMA 20041117

• Prognostic significance of left ventricular mass change during treatment of hypertension.

  JAMA 20041117

• Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals.

  Circulation research 20041112

• NO-sartans: a new class of pharmacodynamic hybrids as cardiovascular drugs.

  Journal of medicinal chemistry 20041104

• Angiotensin II induces carbon monoxide production in the perfused kidney: relationship to protein kinase C activation.

  American journal of physiology. Renal physiology 20041101

• Therapeutic efficacy of an angiotensin II receptor antagonist in patients with nonalcoholic steatohepatitis.

  Hepatology (Baltimore, Md.) 20041101

• Oxidant stress in kidneys of spontaneously hypertensive rats involves both oxidase overexpression and loss of extracellular superoxide dismutase.

  American journal of physiology. Renal physiology 20041101

• ANG II in the paraventricular nucleus potentiates the cardiac sympathetic afferent reflex in rats with heart failure.

  Journal of applied physiology (Bethesda, Md. : 1985) 20041101

• Contribution of the endothelin and renin-angiotensin systems to the vascular changes in rats chronically treated with ouabain.

  British journal of pharmacology 20041101

• Losartan and the United States costs of end-stage renal disease by baseline albuminuria in patients with type 2 diabetes and nephropathy.

  Kidney international. Supplement 20041101

• Angiotensin type 2 receptor neuroprotection against chemical hypoxia is dependent on the delayed rectifier K+ channel, Na+/Ca2+ exchanger and Na+/K+ ATPase in primary cortical cultures.

  Neuroscience research 20041101

• Angiotensin II type 1 receptor blockers reduce tissue factor activity and plasminogen activator inhibitor type-1 antigen in hypertensive patients: a randomized, double-blind, placebo-controlled study.

  Atherosclerosis 20041101

• Albumin up-regulates the type II transforming growth factor-beta receptor in cultured proximal tubular cells.

  Kidney international 20041101

• Telmisartan/hydrochlorothiazide combination therapy in the treatment of essential hypertension.

  Expert opinion on pharmacotherapy 20041101

• Losartan for the treatment of hypertension and left ventricular hypertrophy: the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study.

  Expert opinion on pharmacotherapy 20041101

• Angiotensin II mediates acinar cell apoptosis during the development of rat pancreatic fibrosis by AT1R.

  Pancreas 20041101

• Moxonidine normalizes sympathetic hyperactivity in patients with eprosartan-treated chronic renal failure.

  Journal of the American Society of Nephrology : JASN 20041101

• Effects of losartan and chlorthalidone on blood pressure and renal vascular resistance index in non-diabetic patients with essential hypertension and normal renal function.

  Journal of cardiovascular pharmacology 20041101

• Losartan inhibited expression of matrix metalloproteinases in rat atherosclerotic lesions and angiotensin II-stimulated macrophages.

  Acta pharmacologica Sinica 20041101

• AT1 receptor in rostral ventrolateral medulla mediating blunted baroreceptor reflex in spontaneously hypertensive rats.

  Acta pharmacologica Sinica 20041101

• The role of angiotensin antagonism in stroke prevention in patients with hypertension: focus on losartan.

  Current medical research and opinion 20041101

• Combination angiotensin receptor blocker/hydrochlorothiazide as initial therapy in the treatment of patients with severe hypertension.

  Journal of clinical hypertension (Greenwich, Conn.) 20041101

• Aldosterone escape during blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy is associated with enhanced decline in glomerular filtration rate.

  Diabetologia 20041101

• Losartan in preascitic cirrhosis.

  The American journal of gastroenterology 20041101

• [The effects of losartan on pulmonary arterial collagen and AT1 in chronic hypoxic rats].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20041101

• Potentiation by angiotensin II of spontaneous excitatory postsynaptic currents in rat supraoptic magnocellular neurones.

  Journal of neuroendocrinology 20041101

• Current management of gout in patients unresponsive or allergic to allopurinol.

  Joint, bone, spine : revue du rhumatisme 20041101

• Superoxide mediates sympathoexcitation in heart failure: roles of angiotensin II and NAD(P)H oxidase.

  Circulation research 20041029

• Induced fetal depressor or pressor responses associated with c-fos by intravenous or intracerebroventricular losartan.

  Brain research. Developmental brain research 20041015

• Effect of losartan versus atenolol on aortic valve sclerosis (a LIFE substudy).

  The American journal of cardiology 20041015

• Modification of myosin protein and gene expression in failing hearts due to myocardial infarction by enalapril or losartan.

  Biochimica et biophysica acta 20041014

• Hypoxia-responsive growth factors upregulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells.

  Journal of applied physiology (Bethesda, Md. : 1985) 20041001

• Losartan, an angiotensin II (AT1) receptor antagonist, preserves cerebral blood flow in hypertensive patients with a history of stroke.

  Journal of human hypertension 20041001

• Angiotensin II-induced relaxation of anococcygeus smooth muscle via desensitization of AT1 receptor, and activation of AT2 receptor associated with nitric-oxide synthase pathway.

  The Journal of pharmacology and experimental therapeutics 20041001

• The renoprotective effects of structured care in a clinical trial setting in type 2 diabetic patients with nephropathy.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041001

• Bolus injection of human UII in conscious rats evokes a biphasic haemodynamic response.

  British journal of pharmacology 20041001

• Losartan for treatment of psychogenic polydipsia.

  The Annals of pharmacotherapy 20041001

• Molecular and clinical response to angiotensin II receptor antagonist in kidney transplant patients with chronic allograft nephropathy.

  Transplant international : official journal of the European Society for Organ Transplantation 20041001

• The renal protective effects of angiotensin II receptor blockers in type 2 diabetes mellitus.

  The Annals of pharmacotherapy 20041001

• A pharmacological differentiation between postjunctional (AT1A) and prejunctional (AT1B) angiotensin II receptors in the rabbit aorta.

  Naunyn-Schmiedeberg's archives of pharmacology 20041001

• Mesangial expression of angiotensin II receptor in IgA nephropathy and its regulation by polymeric IgA1.

  Kidney international 20041001

• The impact of serum uric acid on cardiovascular outcomes in the LIFE study.

  Kidney international 20041001

• Take the side-effects of drugs into account.

  Lancet (London, England) 20041001

• A comparative study of first-derivative spectrophotometry and high-performance liquid chromatography applied to the determination of losartan potassium in tablets.

  Chemical & pharmaceutical bulletin 20041001

• [Pharmacological profiles and clinical effects of olmesartan medoxomil, a novel angiotensin II receptor blocker].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20041001

• Losartan improves regional left ventricular systolic and diastolic function in patients with hypertension: accurate evaluation using a newly developed color-coded tissue doppler imaging technique.

  Journal of cardiac failure 20041001

• Antihypertensive and renoprotective efficacy and safety of losartan. A long-term study in children with renal disorders.

  American journal of hypertension 20041001

• Combined therapy of enalapril and losartan attenuates histologic progression in immunoglobulin A nephropathy.

  Pediatrics international : official journal of the Japan Pediatric Society 20041001

• Inhibition of the effect of high glucose on the expression of Smad in human peritoneal mesothelial cells.

  The International journal of artificial organs 20041001

• Effect of losartan, an angiotensin II antagonist, on hepatic fibrosis induced by CCl4 in rats.

  Digestive diseases and sciences 20041001

• A ternary complex of transcription factors, Nishéd and NFATc4, and co-activator p300 bound to an intronic sequence, intronic regulatory element, is pivotal for the up-regulation of myosin light chain-2v gene in cardiac hypertrophy.

  The Journal of biological chemistry 20040924

• Pressor response to CSF sodium in mice: mediation by a ouabain-like substance and renin-angiotensin system in the brain.

  Brain research 20040924

• Antibodies from preeclamptic patients stimulate increased intracellular Ca2+ mobilization through angiotensin receptor activation.

  Circulation 20040921

• Angiotensin converting enzyme and the arrhythmogenic action of angiotensin I: cardiac cell membrane as a site of angiotensin I conversion.

  Regulatory peptides 20040915

• Regression of hypertensive left ventricular hypertrophy by losartan compared with atenolol: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial.

  Circulation 20040914

• Enhanced activity of angiotensin II-sensitive neurons in the anterior hypothalamic area of spontaneously hypertensive rats.

  Brain research 20040910

• Angiotensin II attenuates NMDA receptor-mediated neuronal cell death and prevents the associated reduction in Bcl-2 expression.

  Brain research. Molecular brain research 20040910

• Androgens augment proximal tubule transport.

  American journal of physiology. Renal physiology 20040901

• Angiotensin II inhibits NaCl absorption in the rat medullary thick ascending limb.

  American journal of physiology. Renal physiology 20040901

• Angiotensin II stimulates nitric oxide production in pulmonary artery endothelium via the type 2 receptor.

  American journal of physiology. Lung cellular and molecular physiology 20040901

• Reduction of vascular noradrenaline sensitivity by AT1 antagonists depends on functional sympathetic innervation.

  Hypertension (Dallas, Tex. : 1979) 20040901

• Intracellular and extracellular angiotensin II enhance the L-type calcium current in the failing heart.

  Hypertension (Dallas, Tex. : 1979) 20040901

• Ouabain-induced hypertension alters the participation of endothelial factors in alpha-adrenergic responses differently in rat resistance and conductance mesenteric arteries.

  British journal of pharmacology 20040901

• Does albuminuria predict cardiovascular outcome on treatment with losartan versus atenolol in hypertension with left ventricular hypertrophy? A LIFE substudy.

  Journal of hypertension 20040901

• Therapeutic approaches in the prevention of cardiovascular disease in metabolic syndrome and in patients with type 2 diabetes.

  Current opinion in cardiology 20040901

• Anemia and end-stage renal disease in patients with type 2 diabetes and nephropathy.

  Kidney international 20040901

• Effect of angiotensin II type 1 receptor on delayed rectifier potassium current in catecholaminergic CATH.a cells.

  Acta pharmacologica Sinica 20040901

• Effect of enalapril and losartan on cytokines in patients with stable angina pectoris awaiting coronary artery bypass grafting and their interaction with polymorphisms in the interleukin-6 gene.

  The American journal of cardiology 20040901

• Role of the renin-angiotensin system in hepatic ischemia reperfusion injury in rats.

  Hepatology (Baltimore, Md.) 20040901

• Angiotensin II signals mechanical stretch-induced cardiac matrix metalloproteinase expression via JAK-STAT pathway.

  Journal of molecular and cellular cardiology 20040901

• Emerging trends for prevention and treatment of diabetic nephropathy: blockade of the RAAS and BP control.

  Journal of managed care pharmacy : JMCP 20040901

• Relation of impaired left ventricular filling to systolic midwall mechanics in hypertensive patients with normal left ventricular systolic chamber function: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) study.

  American heart journal 20040901

• Angiotensin receptor blockade decreases markers of vascular inflammation.

  Journal of cardiovascular pharmacology 20040901

• Ouabain at nanomolar concentration promotes synthesis and release of angiotensin II from the endothelium of the tail vascular bed of spontaneously hypertensive rats.

  Journal of cardiovascular pharmacology 20040901

• [Serum uric acid--a cardiovasular risk factor?].

  Therapeutische Umschau. Revue therapeutique 20040901

• Combination of losartan and hydrochlorothiazide: in vivo bioequivalence.

  Arzneimittel-Forschung 20040901

• Reassessing guidelines for heart failure.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20040901

• Renin-angiotensin system blockade prevents the increase in plasma transforming growth factor beta 1, and reduces proteinuria and kidney hypertrophy in the streptozotocin-diabetic rat.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20040901

• Stroke prevention with losartan in the context of other antihypertensive drugs.

  Drugs of today (Barcelona, Spain : 1998) 20040901

• Angiotensin II-receptor antagonist losartan does not prevent nitroglycerin tolerance in patients with coronary artery disease.

  Cardiovascular drugs and therapy 20040901

• Cost-effectiveness of losartan versus atenolol in treating hypertension--an analysis of the LIFE study from a Swiss perspective.

  Cardiovascular drugs and therapy 20040901

• Mechanism of improving effect of losartan on insulin sensitivity of non-insulin-dependent diabetes mellitus rats.

  Sheng li xue bao : [Acta physiologica Sinica] 20040825

• Albuminuria, a therapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathy.

  Circulation 20040824

• [Despite drug treatment, ever second hypertensive patient with morning blood pressure too high].

  MMW Fortschritte der Medizin 20040819

• Rapid electrical stimulation of contraction modulates gap junction protein in neonatal rat cultured cardiomyocytes: involvement of mitogen-activated protein kinases and effects of angiotensin II-receptor antagonist.

  Journal of the American College of Cardiology 20040818

• Evidence of a novel intracrine mechanism in angiotensin II-induced cardiac hypertrophy.

  Regulatory peptides 20040815

• Angiotensin II and angiotensin-(1-7) inhibit the inner cortex Na+ -ATPase activity through AT2 receptor.

  Regulatory peptides 20040815

• Pressor effects of electrical stimulation of medial prefrontal cortex in unanesthetized rats.

  Journal of neuroscience research 20040815

• Effect of chronic stress on the cardiac baroreflex in the post-weanling rat.

  Life sciences 20040813

• [Kidney and hypertension--evidence based medicine].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20040810

• The cost-effectiveness of losartan in type 2 diabetics with nephropathy in Switzerland--an analysis of the RENAAL study.

  Swiss medical weekly 20040807

• Different effects of antihypertensive therapies based on losartan or atenolol on ultrasound and biochemical markers of myocardial fibrosis: results of a randomized trial.

  Circulation 20040803

• Introgression of chromosome 13 in Dahl salt-sensitive genetic background restores cerebral vascular relaxation.

  American journal of physiology. Heart and circulatory physiology 20040801

• Chronic AT(1) receptor blockade alters mechanisms mediating responses to hypoxia in rat skeletal muscle resistance arteries.

  American journal of physiology. Heart and circulatory physiology 20040801

• Studies on the glycemic and lipidemic effect of monopril and losartan in normal and diabetic rats.

  Pharmacological research 20040801

• Renal nitric oxide production is decreased in diabetic rats and improved by AT1 receptor blockade.

  Journal of hypertension 20040801

• N-terminal pro-brain natriuretic peptide predicts cardiovascular events in patients with hypertension and left ventricular hypertrophy: a LIFE study.

  Journal of hypertension 20040801

• Efficacy and safety of DALI-LDL-apheresis in two patients treated with the angiotensin II-receptor 1 antagonist losartan.

  Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20040801

• Comparison of the effects of angiotensin receptor antagonist, angiotensin converting enzyme inhibitor, and their combination on regression of left ventricular hypertrophy of diabetes type 2 patients on recent onset hemodialysis therapy.

  Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20040801

• Clinical characteristics of normotensive renal transplant recipients with microalbuminuria and effects of angiotensin II type I receptor antagonist on urinary albumin excretion.

  International journal of urology : official journal of the Japanese Urological Association 20040801

• Functional impact of CYP2C95, CYP2C96, CYP2C98, and CYP2C911 in vivo among black Africans.

  Clinical pharmacology and therapeutics 20040801

• The JNC 7 approach compared to conventional treatment in diabetic patients with hypertension: a double-blind trial of initial monotherapy vs. combination therapy.

  Journal of clinical hypertension (Greenwich, Conn.) 20040801

• Practical efficacy of telmisartan for decreasing morning home blood pressure and pulse wave velocity in patients with mild-to-moderate hypertension.

  Hypertension research : official journal of the Japanese Society of Hypertension 20040801

• Cardioprotective effects of vasopeptidase inhibition vs. angiotensin type 1-receptor blockade in spontaneously hypertensive rats on a high salt diet.

  Hypertension research : official journal of the Japanese Society of Hypertension 20040801

• Changes in beta-adrenoceptors in heart failure due to myocardial infarction are attenuated by blockade of renin-angiotensin system.

  Molecular and cellular biochemistry 20040801

• Contractile responses of aortae from WKY and SHR to vasoconstrictors.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20040801

• Neurohumoral mechanisms involved in the hypertensive response elicited by bilateral carotid occlusion in conscious intact or chronically sympathectomized rats.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20040801

• Hypertension caused by angiotensin II infusion involves increased superoxide production in the central nervous system.

  Circulation research 20040723

• Angiotensinergic pathway through the median preoptic nucleus in the control of oxytocin secretion and water and sodium intake.

  Brain research 20040716

• The role of the pancreatic renin-angiotensin system in acinar digestive enzyme secretion and in acute pancreatitis.

  Regulatory peptides 20040715

• [Optimizing antihypertensive therapy. In 5 years 35,000 strokes are preventable].

  MMW Fortschritte der Medizin 20040708

• Losartan ameliorates progression of glomerular structural changes in diabetic KKAy mice.

  Life sciences 20040702

• Alterations of adenylyl cyclase and G proteins in aortocaval shunt-induced heart failure.

  American journal of physiology. Heart and circulatory physiology 20040701

• Treatment of Wilms tumor-related hypertension with losartan and captopril.

  Pediatric nephrology (Berlin, Germany) 20040701

• Electrocardiographic strain pattern and prediction of cardiovascular morbidity and mortality in hypertensive patients.

  Hypertension (Dallas, Tex. : 1979) 20040701

• Influence of the 4G/5G PAI-1 genotype on angiotensin II-stimulated human endothelial cells and in patients with hypertension.

  Cardiovascular research 20040701

• CYP2C9 genetic variants and losartan oxidation in a Turkish population.

  European journal of clinical pharmacology 20040701

• Activation of the renin-angiotensin system in alpha-calcitonin gene-related peptide/calcitonin gene knockout mice.

  Journal of hypertension 20040701

• How much echo left ventricular hypertrophy would be missed in diabetics by applying the Losartan Intervention For Endpoint Reduction electrocardiogram criteria to select patients for angiotensin receptor blockade?

  Journal of hypertension 20040701

• Intrarenal Renin-Angiotensin system is upregulated in experimental model of progressive renal disease induced by chronic inhibition of nitric oxide synthesis.

  Journal of the American Society of Nephrology : JASN 20040701

• Perivascular delivery of losartan with surgical fibrin glue prevents neointimal hyperplasia after arterial injury.

  Journal of vascular surgery 20040701

• Restoration of cardiomyocyte functional properties by angiotensin II receptor blockade in diabetic rats.

  Diabetes 20040701

• Angiotensin AT1 receptor upregulates expression of basic fibroblast growth factor, basic fibroblast growth factor receptor and coreceptor in human coronary smooth muscle cells.

  Basic research in cardiology 20040701

• Losartan in diabetic nephropathy.

  Expert review of cardiovascular therapy 20040701

• Altered effects of angiotensin ii type 1 and type 2 receptor blockers on cardiac norepinephrine release and inotropic responses during cardiac sympathetic nerve stimulation in aorto-caval shunt rats.

  Circulation journal : official journal of the Japanese Circulation Society 20040701

• Evidence for the role of angiotensin II biosynthesis in the rat internal anal sphincter tone.

  Gastroenterology 20040701

• Involvement of oxidative stress in the profibrotic action of aldosterone. Interaction wtih the renin-angiotension system.

  American journal of hypertension 20040701

• In vivo effect of losartan on platelet aggregation in patients with hypertension.

  Heart and vessels 20040701

• Evaluation of a technique of inducing hypertensive renal insufficiency in cats.

  American journal of veterinary research 20040701

• Diuretics in the LIFE study.

  Lancet (London, England) 20040701

• [Clinical observation on treatment of diabetic nephropathy with compound fructus arctii mixture].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040701

• Changes in skeletal muscle SR Ca2+ pump in congestive heart failure due to myocardial infarction are prevented by angiotensin II blockade.

  Canadian journal of physiology and pharmacology 20040701

• [Angiotensin type 1 receptor blocker reduced proteinuria in patients of focal glomerular sclerosis].

  Nihon Jinzo Gakkai shi 20040701

• Beta-blockers in heart failure: is more better?

  Current heart failure reports 20040701

• Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors.

  Circulation research 20040625

• Valsartan treatment of hypertension--does VALUE add value?

  Lancet (London, England) 20040619

• Combined inhibition of angiotensin II and endothelin suppresses the brain natriuretic peptide response to developing heart failure.

  Clinical science (London, England : 1979) 20040601

• Stimulation of cardiac sympathetic nerve activity by central angiotensinergic mechanisms in conscious sheep.

  American journal of physiology. Regulatory, integrative and comparative physiology 20040601

• Neonatal RAS inhibition changes the phenotype of the developing thick ascending limb of Henle.

  American journal of physiology. Renal physiology 20040601

• Transactivation of the insulin-like growth factor-I receptor by angiotensin II mediates downstream signaling from the angiotensin II type 1 receptor to phosphatidylinositol 3-kinase.

  Endocrinology 20040601

• Usefulness of the assessment of the appropriateness of left ventricular mass to detect left ventricular systolic and diastolic abnormalities in absence of echocardiographic left ventricular hypertrophy: the LIFE study.

  Journal of human hypertension 20040601

• Population impact of losartan use on stroke in the European Union (EU): projections from the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study.

  Journal of human hypertension 20040601

• Sex-related difference in regression of left ventricular hypertrophy with antihypertensive treatment: the LIFE study.

  Journal of human hypertension 20040601

• Impact of valvular regurgitation on left ventricular geometry and function in hypertensive patients with left ventricular hypertrophy: the LIFE study.

  Journal of human hypertension 20040601

• Regression of electrocardiographic left ventricular hypertrophy predicts regression of echocardiographic left ventricular mass: the LIFE study.

  Journal of human hypertension 20040601

• Long-term plasma catecholamines in patients with hypertension and left ventricular hypertrophy treated with losartan or atenolol: ICARUS, a LIFE substudy.

  Journal of human hypertension 20040601

• Role of brain and peripheral angiotensin II in hypertension and altered arterial baroreflex programmed during fetal life in rat.

  Pediatric research 20040601

• Association of left bundle branch block with left ventricular structure and function in hypertensive patients with left ventricular hypertrophy: the LIFE study.

  Journal of human hypertension 20040601

• Effects of SCH27899 (Ziracin), an oligosaccharide everninomicin antibiotic, on urate kinetics in humans.

  European journal of clinical pharmacology 20040601

• Impact of age on left ventricular hypertrophy regression during antihypertensive treatment with losartan or atenolol (the LIFE study).

  Journal of human hypertension 20040601

• Alcohol consumption and cardiovascular risk in hypertensives with left ventricular hypertrophy: the LIFE study.

  Journal of human hypertension 20040601

• Bradykinin contributes to the systemic hemodynamic effects of chronic angiotensin-converting enzyme inhibition in patients with heart failure.

  Arteriosclerosis, thrombosis, and vascular biology 20040601

• Stimulation of cyclic GMP production via AT2 and B2 receptors in the pressure-overloaded aorta after banding.

  Hypertension (Dallas, Tex. : 1979) 20040601

• Serum uric acid-lowering therapies: where are we heading in management of hyperuricemia and the potential role of uricase.

  Current rheumatology reports 20040601

• Losartan modulation on NOS isoforms and COX-2 expression in early renal fibrogenesis in unilateral obstruction.

  Kidney international 20040601

• Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: lessons from RENAAL.

  Kidney international 20040601

• Subclinical alteration of taste sensitivity induced by candesartan in healthy subjects.

  British journal of clinical pharmacology 20040601

• Angiotensin II increases Pax-2 expression in fetal kidney cells via the AT2 receptor.

  Journal of the American Society of Nephrology : JASN 20040601

• The LIFE Trial in 2004.

  Journal of human hypertension 20040601

• Comparison of effects of losartan, irbesartan, and candesartan on flow-mediated brachial artery dilation and on inflammatory and thrombolytic markers in patients with systemic hypertension.

  The American journal of cardiology 20040601

• Role of bradykinin B2-receptor in the sympathoadrenal effects of 'new pressor protein' related to human blood coagulation factor XII fragment.

  Journal of hypertension 20040601

• Angiotensin receptor blockade improves arterial distensibility and reduces exercise-induced pressor responses in obese hypertensive patients with the metabolic syndrome.

  American journal of hypertension 20040601

• Haemoglobin predicts survival in patients with chronic heart failure: a substudy of the ELITE II trial.

  European heart journal 20040601

• Uric acid levels and vascular disease.

  Current medical research and opinion 20040601

• Differential response of human cardiac fibroblasts to angiotensin I and angiotensin II.

  Peptides 20040601

• Incidence of hyperkalemia in high risk patients during treatment with an angiotensin converting enzyme inhibitor (Lisinopril) versus an angiotensin II receptor blocker (Losartan).

  South Dakota journal of medicine 20040601

• A putative placebo comparison of the SCOPE and LIFE trials.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20040601

• Tonic levels of angiotensin II reduce tonic levels of vascular nitric oxide even in salt-replete man.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20040601

• Losartan may prevent the elevation of plasma glucose, corticosterone and catecholamine levels induced by chronic stress.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20040601

• Renin-angiotensin blockade attenuates cardiac myofibrillar remodelling in chronic diabetes.

  Molecular and cellular biochemistry 20040601

• Effects of angiotensin and vasopressin V(1) receptors on water and sodium intake induced by injection of vasopressin into lateral septal area.

  Regulatory peptides 20040515

• Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells.

  Circulation research 20040514

• Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: a possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosterone.

  Circulation 20040511

• Design, synthesis, structural studies, biological evaluation, and computational simulations of novel potent AT(1) angiotensin II receptor antagonists based on the 4-phenylquinoline structure.

  Journal of medicinal chemistry 20040506

• Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity.

  Circulation 20040504

• Upregulation of angiotensin II type 2 receptor expression in estrogen-induced pituitary hyperplasia.

  American journal of physiology. Endocrinology and metabolism 20040501

• Role of angiotensin II in ischemia/reperfusion-induced leukocyte-endothelium interactions in the colon.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040501

• Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors.

  Hypertension (Dallas, Tex. : 1979) 20040501

• Angiotensin type-1 receptor blockade increases ACE 2 expression in the heart.

  Hypertension (Dallas, Tex. : 1979) 20040501

• Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity.

  Hypertension (Dallas, Tex. : 1979) 20040501

• QRS duration and QT interval predict mortality in hypertensive patients with left ventricular hypertrophy: the Losartan Intervention for Endpoint Reduction in Hypertension Study.

  Hypertension (Dallas, Tex. : 1979) 20040501

• Nitric oxide and angiotensin II: neuromodulation of thermoregulation during combined heat and hypohydration stress.

  Brain research 20040501

• Tonic angiotensinergic inputs to neurons in the anterior hypothalamic area of rats.

  Brain research 20040501

• Cardiac sympathetic afferent stimulation impairs baroreflex control of renal sympathetic nerve activity in rats.

  American journal of physiology. Heart and circulatory physiology 20040501

• Renal expression of COX-2, ANG II, and AT1 receptor in remnant kidney: strong renoprotection by therapy with losartan and a nonsteroidal anti-inflammatory.

  American journal of physiology. Renal physiology 20040501

• Hereditary angioedema type III, angioedema associated with angiotensin II receptor antagonists, and female sex.

  The American journal of medicine 20040501

• The effect of losartan on global and focal cerebral perfusion and on renal function in hypertensives in mild early ischaemic stroke.

  Journal of hypertension 20040501

• The impact of CYP2C9 genetics and oral contraceptives on cytochrome P450 2C9 phenotype.

  Drug metabolism and disposition: the biological fate of chemicals 20040501

• Neonatal losartan treatment suppresses renal expression of molecules involved in cell-cell and cell-matrix interactions.

  Journal of the American Society of Nephrology : JASN 20040501

• Local actions of endogenous angiotensin II in injured glomeruli.

  Journal of the American Society of Nephrology : JASN 20040501

• Angiotensin II stimulates phosphorylation of 4E-binding protein 1 and p70 S6 kinase in cultured vascular smooth muscle cells.

  Acta pharmacologica Sinica 20040501

• Losartan reduces the costs associated with nephropathy and end-stage renal disease from type 2 diabetes: Economic evaluation of the RENAAL study from a Canadian perspective.

  The Canadian journal of cardiology 20040501

• Doxorubicine-congestive heart failure-increased big endothelin-1 plasma concentration: reversal by amlodipine, losartan, and gastric pentadecapeptide BPC157 in rat and mouse.

  Journal of pharmacological sciences 20040501

• Effects of Losartan on acute atrial electrical remodeling.

  Chinese medical journal 20040501

• [A case of intraoperative hyperkalemia induced with administration of an angiotensin II receptor antagonist (AIIA) and intake of dried persimmons].

  Masui. The Japanese journal of anesthesiology 20040501

• Anti-proteinuric effects of combination therapy with enalapril and losartan in patients with nephropathy due to type 2 diabetes.

  International journal of clinical practice 20040501

• Prevention and treatment of stroke in patients with hypertension.

  Clinical therapeutics 20040501

• Losartan reverses fibrotic changes in cortical renal tissue induced by ischemia or ischemia-reperfusion without changes in renal function.

  Molecular and cellular biochemistry 20040501

• Losartan-ramipril combination treatment.

  The Journal of the Association of Physicians of India 20040501

• Interaction between paraventricular nucleus and medial septal area on the renal effects induced by adrenaline.

  Autonomic neuroscience : basic & clinical 20040430

• [Blood pressure increases risk for dementia and stroke. Antihypertensive drugs for mental degeneration?].

  MMW Fortschritte der Medizin 20040429

• Angiotensin II receptors in the arcuate nucleus mediate stress-induced reduction of prolactin secretion in steroid-primed ovariectomized and lactating rats.

  Brain research 20040423

• Losartan for microalbuminuria in normotensive type 2 diabetes mellitus.

  Annals of internal medicine 20040420

• Losartan for microalbuminuria in normotensive type 2 diabetes mellitus.

  Annals of internal medicine 20040420

• 'Network leaning' as a mechanism of insurmountable antagonism of the angiotensin II type 1 receptor by non-peptide antagonists.

  The Journal of biological chemistry 20040409

• Effects of losartan in hypertension without vascular disease.

  Annals of internal medicine 20040406

• Signaling cascade of ANG II-induced inhibition of alpha-MG uptake in renal proximal tubule cells.

  American journal of physiology. Renal physiology 20040401

• Effect of a perinatal high-salt diet on blood pressure control mechanisms in young Sprague-Dawley rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20040401

• Novel dual action AT1 and ETA receptor antagonists reduce blood pressure in experimental hypertension.

  The Journal of pharmacology and experimental therapeutics 20040401

• Cerebral ischemia enhances vascular angiotensin AT1 receptor-mediated contraction in rats.

  Stroke 20040401

• Fenofibrate and losartan.

  Annals of the rheumatic diseases 20040401

• Effect of angiotensin II and endothelin-1 receptor blockade on the haemodynamic and hormonal changes after acute blood loss and after retransfusion in conscious dogs.

  Acta physiologica Scandinavica 20040401

• Hypercholesterolemia in rats induces podocyte stress and decreases renal cortical nitric oxide synthesis via an angiotensin II type 1 receptor-sensitive mechanism.

  Journal of the American Society of Nephrology : JASN 20040401

• Renin angiotensin aldosterone system blockade and renal disease in patients with type 2 diabetes. An Asian perspective from the RENAAL Study.

  Diabetes care 20040401

• Preventing type II diabetes mellitus.

  Journal of clinical pharmacology 20040401

• Rationale for the use of combination angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker therapy in heart failure.

  Circulation journal : official journal of the Japanese Circulation Society 20040401

• Hemorrhage during isoflurane-nitrous oxide anesthesia: effects of endothelin-A or angiotensin II receptor blockade or both.

  Anesthesiology 20040401

• Effects of losartan and simvastatin on monocyte-derived microparticles in hypertensive patients with and without type 2 diabetes mellitus.

  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20040401

• Fingernail clubbing and chromonychia associated with the use of angiotensin II receptor blockers.

  Pharmacotherapy 20040401

• Losartan but not enalaprilat acutely reduces reperfusion ventricular tachyarrhythmias in hypertrophied rat hearts after low-flow ischaemia.

  The Journal of pharmacy and pharmacology 20040401

• Interaction between supraoptic nucleus and septal area in the control of water, sodium intake and arterial blood pressure induced by injection of angiotensin II.

  Pharmacology, biochemistry, and behavior 20040401

• Aspirin, superoxide anions and development of hypertension.

  Journal of hypertension 20040401

• Prevention of angiotensin II-induced hypertension, cardiovascular hypertrophy and oxidative stress by acetylsalicylic acid in rats.

  Journal of hypertension 20040401

• Evidence that angiotensin II enhances apomorphine-induced jaw movements via AT1 receptors in the ventrolateral striatum: studies by magnet-sensing system in freely moving rats.

  Methods and findings in experimental and clinical pharmacology 20040401

• [Relativity of nuclear factor-kappaB (P65/Rel-A) and angiotensin II type 1 receptor expression in early stage of lesions of adriamycin nephrosis in young rats and the effects of intervention].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20040401

• Influence of arginine vasopressin receptors and angiotensin receptor subtypes on the water intake and arterial blood pressure induced by vasopressin injected into the lateral septal area of the rat.

  Autonomic neuroscience : basic & clinical 20040331

• Effects of angiotensin II and AIII microinjections into the zona incerta after intra- and extracellular fluid loss.

  Brain research 20040326

• Angiotensin II stimulates DNA synthesis of rat pancreatic stellate cells by activating ERK through EGF receptor transactivation.

  Biochemical and biophysical research communications 20040319

• [Treatment of hypertension in patients with left ventricular hypertrophy].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20040318

• Cardiovascular risk reduction in hypertensive black patients with left ventricular hypertrophy: the LIFE study.

  Journal of the American College of Cardiology 20040317

• Immunohistochemical colocalization of type II angiotensin receptors with somatostatin in rat pancreas.

  Regulatory peptides 20040315

• [Therapeutic strategy for patients with stable-stage chronic kidney failure].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20040310

• [Diagnosis of and therapy for renal hypertension].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20040310

• Renin and angiotensinogen expression and functions in growth and apoptosis of human glioblastoma.

  British journal of cancer 20040308

• Protective effects of the angiotensin II type 1 (AT1) receptor blockade in low-renin deoxycorticosterone acetate (DOCA)-treated spontaneously hypertensive rats.

  Clinical science (London, England : 1979) 20040301

• The effect of central injection of angiotensin-converting enzyme inhibitor and the angiotensin type 1 receptor antagonist on the induction by lipopolysaccharide of fever and brain interleukin-1beta response in rats.

  The Journal of pharmacology and experimental therapeutics 20040301

• Angiotensin II regulation of the Na+ pump involves the phosphatidylinositol-3 kinase and p42/44 mitogen-activated protein kinase signaling pathways in vascular smooth muscle cells.

  Endocrinology 20040301

• The effects of losartan and immobilization stress on heart rate variability and plasma corticosterone levels in rats.

  The International journal of neuroscience 20040301

• The role of bradykinin, AT2 and angiotensin 1-7 receptors in the EDRF-dependent vasodilator effect of angiotensin II on the isolated mesenteric vascular bed of the rat.

  British journal of pharmacology 20040301

• The losartan intervention for endpoint reduction substudy.

  Current cardiology reports 20040301

• Treatment of hypertension and prevention of ischemic stroke.

  Current cardiology reports 20040301

• Mechanisms of angiotensin II-induced expression of B2 kinin receptors.

  American journal of physiology. Heart and circulatory physiology 20040301

• Anti-proteinuric effect of losartan: statistical vs clinical significance.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040301

• Tight blood pressure control decreases apoptosis during renal damage.

  Kidney international 20040301

• The impact of serum uric acid on cardiovascular outcomes in the LIFE study.

  Kidney international 20040301

• Comparison of the antihypertensive effects of the fixed dose combination enalapril 10 mg/nitrendipine 20 mg vs losartan 50 mg/hydrochlorothiazide 12.5 mg, assessed by 24-h ambulatory blood pressure monitoring, in essential hypertensive patients.

  Journal of human hypertension 20040301

• Differential regulation by AT(1) and AT(2) receptors of angiotensin II-stimulated cyclic GMP production in rat uterine artery and aorta.

  British journal of pharmacology 20040301

• Effects of losartan and captopril on left ventricular systolic and diastolic function after acute myocardial infarction: results of the Optimal Trial in Myocardial Infarction with Angiotensin II Antagonist Losartan (OPTIMAAL) echocardiographic substudy.

  American heart journal 20040301

• Clinical inquiries. Are ARBs or ACE inhibitors preferred for nephropathy in diabetes?

  The Journal of family practice 20040301

• Connective tissue growth factor--a novel mediator of angiotensin II-stimulated cardiac fibroblast activation in heart failure in rats.

  Journal of molecular and cellular cardiology 20040301

• Angiotensin receptor blockers in diabetic nephropathy: renal and cardiovascular end points.

  Seminars in nephrology 20040301

• AII antagonists in hypertension, heart failure, and diabetic nephropathy: focus on losartan.

  Current medical research and opinion 20040301

• Advances in the treatment of diabetic renal disease: focus on losartan.

  Current medical research and opinion 20040301

• Uric acid: role in cardiovascular disease and effects of losartan.

  Current medical research and opinion 20040301

• [Effects of angiotensin II receptor blockers, angiotensin converting enzyme inhibitors, 3-hydroxy-3-methyl glutaryl (HMG) CoA reductase inhibitors, amlodipine and epalrestat on cultured basilar artery smooth muscle cell proliferation].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20040301

• Increased plasma adiponectin in losartan-treated type 1 diabetic patients. a mediator of improved insulin sensitivity?

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040301

• Evidence of the role of angiotensin AT(1) receptors in remote renal preconditioning of myocardium.

  Methods and findings in experimental and clinical pharmacology 20040301

• Haemodynamic effects of dual blockade of the renin-angiotensin system in spontaneously hypertensive rats: influence of salt.

  Journal of hypertension 20040301

• Angiotensin receptor antagonist regresses left ventricular hypertrophy associated with diabetic nephropathy in dialysis patients.

  Journal of cardiovascular pharmacology 20040301

• Cross talk between angiotensin II and alpha 1 adrenergic receptors in rabbit aorta: role of endothelium.

  Journal of cardiovascular pharmacology 20040301

• Angiotensin converting enzyme genotype influences the response to the angiotensin II receptor antagonist losartan in patients with hypertension.

  Hypertension research : official journal of the Japanese Society of Hypertension 20040301

• Angiotensin IV stimulates the activity of tyrosine kinases in rat anterior pituitary gland acting via AT1-like receptors?

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040301

• Effects of ACE inhibition and AT1-receptor blockade on haemodynamic responses to L-arginine in Type 1 diabetes.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20040301

• Neurohumoral mechanism in the natriuretic action of intracerebroventricular administration of renin.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20040301

• [Involvement of angiotensin II in pathogenesis of hypertension and target organ damage].

  Nihon rinsho. Japanese journal of clinical medicine 20040301

• [High blood pressure and cardiac hypertrophy].

  Nihon rinsho. Japanese journal of clinical medicine 20040301

• [Hypertension in patients with cardiac hypertrophy].

  Nihon rinsho. Japanese journal of clinical medicine 20040301

• [Hyperuricemia in hypertension].

  Nihon rinsho. Japanese journal of clinical medicine 20040301

• [Organ protection by angiotensin II receptor blockers].

  Nihon rinsho. Japanese journal of clinical medicine 20040301

• [Management of hypertensive patients with cardiovascular damage].

  Nihon rinsho. Japanese journal of clinical medicine 20040301

• [Development of combined drugs (ARB and diuretics)].

  Nihon rinsho. Japanese journal of clinical medicine 20040301

• Pharmacological properties of angiotensin II receptors in cultured rabbit gingival fibroblasts.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20040301

• Effect of angiotensin II and losartan on the phagocytic activity of peritoneal macrophages from Balb/C mice.

  Memorias do Instituto Oswaldo Cruz 20040301

• Evaluation of efficacy and tolerability of Losartan and Ramipril combination in the management of hypertensive patients with associated diabetes mellitus in India (LORD Trial).

  The Journal of the Association of Physicians of India 20040301

• Superoxide is involved in the central nervous system activation and sympathoexcitation of myocardial infarction-induced heart failure.

  Circulation research 20040220

• Recognition of privileged structures by G-protein coupled receptors.

  Journal of medicinal chemistry 20040212

• [When compliance doesn't work out. Calculate the risk of stroke for hypertensive patients!].

  MMW Fortschritte der Medizin 20040212

• Impaired substance P release from renal sensory nerves in SHR involves a pertussis toxin-sensitive mechanism.

  American journal of physiology. Regulatory, integrative and comparative physiology 20040201

• Induction of human CYP2C9 by rifampicin, hyperforin, and phenobarbital is mediated by the pregnane X receptor.

  The Journal of pharmacology and experimental therapeutics 20040201

• Up-regulation of angiotensin II type 2 receptor in rat thoracic aorta by pressure-overload.

  The Journal of pharmacology and experimental therapeutics 20040201

• Prophylactic and therapeutic treatments with AT 1 and AT 2 receptor antagonists and their effects on changes in the severity of pancreatitis.

  The international journal of biochemistry & cell biology 20040201

• Evidence for a causal role of the renin-angiotensin system in vascular dysfunction associated with insulin resistance.

  Hypertension (Dallas, Tex. : 1979) 20040201

• Ganglionic action of angiotensin contributes to sympathetic activity in renin-angiotensinogen transgenic mice.

  Hypertension (Dallas, Tex. : 1979) 20040201

• Effects of the combination of low-dose nifedipine GITS 20 mg and losartan 50 mg in patients with mild to moderate hypertension.

  Journal of cardiovascular pharmacology 20040201

• Temporary losartan or captopril in young SHR induces malignant hypertension despite initial normotension.

  Kidney international 20040201

• Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets.

  Diabetologia 20040201

• Decrease in hypothalamic gamma adducin in rat models of hypertension.

  Hypertension (Dallas, Tex. : 1979) 20040201

• Endogenous angiotensin and pressure modulate brain angiotensinogen and AT1A mRNA expression.

  Hypertension (Dallas, Tex. : 1979) 20040201

• Regional haemodynamic effects of cyclosporine A, tacrolimus and sirolimus in conscious rats.

  British journal of pharmacology 20040201

• Effects of losartan on diabetic maculopathy in type 2 diabetic patients.

  Journal of internal medicine 20040201

• Hypothetical economic analysis of screening for left ventricular hypertrophy in high-risk normotensive populations.

  QJM : monthly journal of the Association of Physicians 20040201

• Low-dose dual blockade of the renin-angiotensin system in patients with primary glomerulonephritis.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20040201

• Angiotensin as a target for the treatment of Alzheimer's disease, anxiety and depression.

  Expert opinion on therapeutic targets 20040201

• Effects of angiotensin II type 1 receptor antagonist, losartan, on ventilatory response to exercise and neurohormonal profiles in patients with chronic heart failure.

  The Japanese journal of physiology 20040201

• Chronic administration of losartan, an angiotensin II receptor antagonist, is not effective in reducing portal pressure in patients with preascitic cirrhosis.

  The American journal of gastroenterology 20040201

• Inhibitory effects of angiotensin on NMDA-induced cytotoxicity in primary neuronal cultures.

  Brain research bulletin 20040201

• Central AII evokes a normal sodium appetite in the Fischer rat, but its low spontaneous sodium intake may be related to reduced excitation and increased inhibition in septo-preoptic AII neurons.

  Brain research bulletin 20040201

• Achieved vs initial blood pressure in predicting renal outcomes.

  Archives of internal medicine 20040126

• Angiotensin II attenuates chemical hypoxia-induced caspase-3 activation in primary cortical neuronal cultures.

  Brain research bulletin 20040115

• Angiotensin II and the fibroproliferative response to acute lung injury.

  American journal of physiology. Lung cellular and molecular physiology 20040101

• Angiotensin II-dependent increased expression of Na+-glucose cotransporter in hypertension.

  American journal of physiology. Renal physiology 20040101

• Relative roles of nitric oxide, prostanoids and angiotensin II in the regulation of canine glomerular hemodynamics. A micropuncture study.

  Kidney & blood pressure research 20040101

• Efficacy of losartan in the treatment of erythrocytosis in a young adult with CRF.

  Pediatric nephrology (Berlin, Germany) 20040101

• Cardiovascular and renal phenotype in mice with one or two renin genes.

  Hypertension (Dallas, Tex. : 1979) 20040101

• Comparison of the role of endothelin, vasopressin and angiotensin in arterial pressure regulation during sevoflurane anaesthesia in dogs.

  British journal of anaesthesia 20040101

• Relative roles of endothelin-1 and angiotensin II in experimental post-ischaemic acute renal failure.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040101

• Valsartan for the treatment of heart failure.

  Expert opinion on pharmacotherapy 20040101

• Prospective and randomized study of the antihypertensive effect and tolerability of three antihypertensive agents, losartan, amlodipine, and lisinopril, in hypertensive patients.

  Heart and vessels 20040101

• Two episodes of anuria and acute pulmonary edema in a losartan-treated patient with solitary kidney.

  Heart and vessels 20040101

• Effects of eplerenone on heart and kidney in two-kidney, one-clip rats.

  American journal of nephrology 20040101

• Gender differences in superoxide generation in microvessels of hypertensive rats: role of NAD(P)H-oxidase.

  Cardiovascular research 20040101

• Intracellular angiotensin II fusion protein alters AT1 receptor fusion protein distribution and activates CREB.

  Journal of molecular and cellular cardiology 20040101

• What have we learned from the current trials?

  The Medical clinics of North America 20040101

• Conformation and bioactivity. Design and discovery of novel antihypertensive drugs.

  Current topics in medicinal chemistry 20040101

• Efforts to understand the molecular basis of hypertension through drug:membrane interactions.

  Current topics in medicinal chemistry 20040101

• Effect of pre- and posttreatment of losartan in feline model of myocardial ischemic-reperfusion injury.

  Methods and findings in experimental and clinical pharmacology 20040101

• Effects of AT1 receptor antagonist losartan on sICAM-1 and TNF-alpha levels in uncomplicated hypertensive patients.

  Angiology 20040101

• Neurohumoral stimulation in type-2-diabetes as an emerging disease concept.

  Cardiovascular diabetology 20040101

• Pharmacological treatment and prevention of heart failure in the diabetic patient.

  Reviews in cardiovascular medicine 20040101

• [Candesartan - a novel AT(1)-angiotensin receptor blocker: peculiarities of pharmacology and experience of use in arterial hypertension].

  Kardiologiia 20040101

• [Effects of the early administration of losartan on ventricular remodeling in rabbits with experimental myocardial infarction].

  Medicina 20040101

• A randomized controlled trial of mycophenolate mofetil in patients with IgA nephropathy [ISRCTN62574616].

  BMC nephrology 20040101

• Concerted action of the renin-angiotensin system, mitochondria, and antioxidant defenses in aging.

  Molecular aspects of medicine 20040101

• Renoprotective effect of losartan in comparison to amlodipine in patients with chronic kidney disease and hypertension--a report of the Japanese Losartan Therapy Intended for the Global Renal Protection in Hypertensive Patients (JLIGHT) study.

  Hypertension research : official journal of the Japanese Society of Hypertension 20040101

• Effect of angiotensin II type 1 receptor blockade on conduit artery tone in subtotally nephrectomized rats.

  Nephron. Physiology 20040101

• Tubular and interstitial cell apoptosis in the streptozotocin-diabetic rat kidney.

  Nephron. Experimental nephrology 20040101

• [Effect of enalapril maleate and lozartan on the size of experimental myocardial infarction, hemoglobin affinity to oxygen and various parameters of lipid peroxidation].

  Eksperimental'naia i klinicheskaia farmakologiia 20040101

• Irbesartan: a review of its use in hypertension and in the management of diabetic nephropathy.

  Drugs 20040101

• Losartan-induced attenuation of blood pressure in L-NAME hypertensive rats is associated with reversal of the enhanced expression of Gi alpha proteins.

  Journal of hypertension 20040101

• Ethanol effects on dentate granule cell LTP.

  Neurotoxicity research 20040101

• Reversal of end-stage renal disease after aortic dissection using renal artery stent: a case report.

  BMC nephrology 20040101

• Losartan may prevent the elevation of plasma glucose levels induced by chronic stress.

  Polish journal of pharmacology 20040101

• [Stomatitis and ageusia induced by candesartan].

  Nephrologie 20040101

• [ACE inhibitors and angiotensin II receptor antagonists in acute coronary syndrome].

  Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti 20040101

• Oxidative stress status in kidney tissue after losartan and atenolol treatment in experimental renal failure.

  Nephron. Experimental nephrology 20040101

• Effects of losartan versus hydrochlorothiazide on indices of endothelial damage/dysfunction, angiogenesis and tissue factor in essential hypertension.

  Blood pressure 20040101

• Angiotensin type 1 receptor blockers in chronic kidney disease.

  Contributions to nephrology 20040101

• Angiotensin II receptor blockers in older patients.

  The American journal of geriatric cardiology 20040101

• Role of angiotensin II and the subfornical organ in the pharmacological actions of ethanol.

  Alcohol and alcoholism (Oxford, Oxfordshire) 20040101

• Olmesartan compared with other angiotensin II receptor antagonists: head-to-head trials.

  Clinical therapeutics 20040101

• Angiotensin II induces hypoxia-inducible factor-1 alpha in PC 12 cells through a posttranscriptional mechanism: role of AT2 receptors.

  American journal of nephrology 20040101

• [Raynaud's phenomenon].

  Reumatismo 20040101

• Effects of losartan and valsartan on left ventricular hypertrophy and function in essential hypertension.

  Advances in therapy 20040101

• Endogenous angiotensin II in the regulation of hypoxic pulmonary vasoconstriction in anaesthetized dogs.

  Critical care (London, England) 20040101

• Combined therapy of cilazapril and losartan has no additive effects in ameliorating adriamycin-induced glomerulopathy.

  Nephron. Physiology 20040101

• [Characteristics of hypotensive effect in patients with arterial hypertension and desaturation signs of obstructive sleep apnea syndrome during sleep].

  Terapevticheskii arkhiv 20040101

• [Blockers of angiotensin receptors: a novel approach to the treatment of secondary pulmonary hypertension].

  Terapevticheskii arkhiv 20040101

• [New potentialities in the treatment of idiopathic hyperaldosteronism].

  Klinicheskaia meditsina 20040101

• Eprosartan effect on fibrinolytic/hemostatic variables in arterial hypertension: a comparative study to losartan.

  Drugs under experimental and clinical research 20040101

• Effects of angiotensin II receptor blocker on proteinuria in renal transplant recipients.

  In vivo (Athens, Greece) 20040101

• Interactions between grapefruit juice and cardiovascular drugs.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101

• Erytrocyte membrane anionic charge in type 2 diabetic patients with retinopathy.

  BMC ophthalmology 20040101

• Management of acute and chronic gouty arthritis: present state-of-the-art.

  Drugs 20040101

• Angiotensin II regulation of TGF-beta in murine mesangial cells involves both PI3 kinase and MAP kinase.

  Annals of clinical and laboratory science 20040101

• Angiotensin II-mediated endothelial dysfunction: role of poly(ADP-ribose) polymerase activation.

  Molecular medicine (Cambridge, Mass.) 20040101

• Prevention of type 2 diabetes mellitus through inhibition of the Renin-Angiotensin system.

  Drugs 20040101

• Effects of combination treatment with losartan and trandolapril on office and ambulatory blood pressures in non-diabetic renal disease: a COOPERATE-ABP substudy.

  American journal of nephrology 20040101

• Losartan reduces left ventricular hypertrophy proportionally to blood pressure reduction in hypertensives, but does not affect diastolic cardiac function.

  Angiology 20040101

• Therapeutic effects of angiotensin (AT1) receptor antagonists: potential contribution of mechanisms other than AT1 receptor blockade.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101

• Reversal of left ventricular hypertrophy: what have recent trials taught us?

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101

• [Losartan versus enalapril in the reduction of left ventricular hypertrophy secondary to systemic arterial hypertension].

  Archivos de cardiologia de Mexico 20040101

• Different effect of losartan and amlodipine on penile structures in male spontaneously hypertensive rats.

  American journal of nephrology 20040101

• Clinical and experimental aspects of olmesartan medoxomil, a new angiotensin II receptor antagonist.

  Cardiovascular drug reviews 20040101

• [The additive antiproteinuric effect of Enalapril and Losartan to normotensive patients with pathology proteinuria].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101

• Low-dose angiotensin II receptor antagonists and angiotensin II-converting enzyme inhibitors alone or in combination for treatment of primary glomerulonephritis.

  Scandinavian journal of urology and nephrology 20040101

• Losartan benefits over atenolol in non-smoking hypertensive patients with left ventricular hypertrophy: the LIFE study.

  Blood pressure 20040101

• Interactions between extracellular and intracellular administered angiotensin II in isolated rat portal vein rings.

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20040101

• Effects of losartan on blood pressure, oxidative stress, and nitrate/nitrite levels in the nitric oxide deficient hypertensive rats.

  Receptors & channels 20040101

• Morphological changes in adrenal cortex--the final effect of angiotensin II receptor antagonists.

  Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20040101

• Pharmacokinetics of Losartan and its Active Metabolite EXP3174 in Healthy Iranian Subjects.

  Clinical drug investigation 20040101

• Effects of subtypes of adrenergic and angiotensinergic antagonists on the water and sodium intake induced by adrenaline injected into the paraventricular nucleus.

  Brain research 20031224

• Angiotensin II signaling pathways mediate expression of cardiac T-type calcium channels.

  Circulation research 20031212

• Coronary microvascular endothelial stunning after acute pressure overload in the conscious dog is caused by oxidant processes: the role of angiotensin II type 1 receptor and NAD(P)H oxidase.

  Circulation 20031209

• [New options against undertreatment].

  MMW Fortschritte der Medizin 20031204

• Albuminuria and cardiovascular risk in hypertensive patients with left ventricular hypertrophy: the LIFE study.

  Annals of internal medicine 20031202

• Growth hormone regulation of glomerular AT1 angiotensin receptors in adult uninephrectomized male rats.

  American journal of physiology. Renal physiology 20031201

• Differential vasoconstrictions induced by angiotensin II: role of AT1 and AT2 receptors in isolated C57BL/6J mouse blood vessels.

  American journal of physiology. Heart and circulatory physiology 20031201

• Thyroxine-induced cardiac hypertrophy: influence of adrenergic nervous system versus renin-angiotensin system on myocyte remodeling.

  American journal of physiology. Regulatory, integrative and comparative physiology 20031201

• The cross-talk between angiotensin and insulin differentially affects phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-mediated signaling in rat heart: implications for insulin resistance.

  Endocrinology 20031201

• Angiotensin II involvement in adaptive enteric oxalate excretion in rats with chronic renal failure induced by hyperoxaluria.

  Urological research 20031201

• Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren.

  Hypertension (Dallas, Tex. : 1979) 20031201

• Blood pressure and diabetic nephropathy.

  Current diabetes reports 20031201

• Essential roles for angiotensin receptor AT1a in bleomycin-induced apoptosis and lung fibrosis in mice.

  The American journal of pathology 20031201

• Polymeric IgA1 from patients with IgA nephropathy upregulates transforming growth factor-beta synthesis and signal transduction in human mesangial cells via the renin-angiotensin system.

  Journal of the American Society of Nephrology : JASN 20031201

• Nitric oxide-dependent antiplatelet action of AT1-receptor antagonists in a pulmonary thromboembolism in mice.

  Journal of cardiovascular pharmacology 20031201

• Antihypertensive effects of two fixed-dose combinations of losartan and hydrochlorothiazide versus hydrochlorothiazide monotherapy in subjects with ambulatory systolic hypertension.

  American journal of hypertension 20031201

• Angiotensin II AT(1)-receptor induces biglycan in neonatal cardiac fibroblasts via autocrine release of TGFbeta in vitro.

  Cardiovascular research 20031201

• Induction of myocardial biglycan in heart failure in rats--an extracellular matrix component targeted by AT(1) receptor antagonism.

  Cardiovascular research 20031201

• A low dose of angiotensin II increases inotropism through activation of reverse Na(+)/Ca(2+) exchange by endothelin release.

  Cardiovascular research 20031201

• Different effects of losartan and delapril on plasma PAI-1 levels in patients with mild to moderate hypertension.

  International journal of cardiology 20031201

• Partial prevention of changes in SR gene expression in congestive heart failure due to myocardial infarction by enalapril or losartan.

  Molecular and cellular biochemistry 20031201

• Stress and angiotensin II: novel therapeutic opportunities.

  Current drug targets. CNS and neurological disorders 20031201

• Angiotensin II antagonists in the treatment of hypertension-effective and efficient?

  Herz 20031201

• Subfornical organ lesion attenuates chronic hypotensive effects of losartan in salt-replete rats.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20031201

• Combined renin-angiotensin system blockade and dietary sodium restriction impairs cardiomyocyte contractility.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20031201

• Patient with diffuse mesangial and endocapillary proliferative glomerulonephritis with hypocomplementemia and elevated anti-streptolysin O treated with prednisolone, angiotensin-converting enzyme inhibitor, and angiotensin II receptor antagonist.

  Clinical and experimental nephrology 20031201

• Effect of angiotensin II type 2 receptor blockade on activation of mitogen-activated protein kinases after ischemia-reperfusion in isolated working rat hearts.

  Journal of cardiovascular pharmacology and therapeutics 20031201

• Losartan and other angiotensin II antagonists for nephropathy in type 2 diabetes mellitus: a review of the clinical trial evidence.

  Clinical therapeutics 20031201

• [Is early discharge possible in patients with uncomplicated heart failure? Cost-efficacy analysis].

  Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20031201

• Angiotensins II and IV stimulate the rat anterior pituitary cell proliferation independently of the AT1 receptor subtype.

  Neuro endocrinology letters 20031201

• Proportion of treatment effect (PTE) explained by a surrogate marker.

  Statistics in medicine 20031130

• AT1b receptor predominantly mediates contractions in major mouse blood vessels.

  Circulation research 20031128

• [Progress in the prevention of type 2 diabetes].

  Wiener klinische Wochenschrift 20031128

• Involvement of reactive oxygen species in angiotensin II-induced endothelin-1 gene expression in rat cardiac fibroblasts.

  Journal of the American College of Cardiology 20031119

• Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia.

  British journal of cancer 20031117

• Expression and localization of AT1 receptors in hepatic Kupffer cells: its potential role in regulating a fibrogenic response.

  Regulatory peptides 20031115

• Evidence for a functional role of angiotensin II type 2 receptor in the cardiac hypertrophic process in vivo in the rat heart.

  Circulation 20031111

• [Production of aldosterone by rat mesangial cell and the accumulation of extracellular matrix induced by aldosterone].

  Zhonghua yi xue za zhi 20031110

• Effect of losartan on the blood-brain barrier permeability in diabetic hypertensive rats.

  Life sciences 20031107

• [To protect the hypertensive patient from complications. Blood pressure lowering is not equal to blood pressure lowering].

  MMW Fortschritte der Medizin 20031106

• Losartan corrects abnormal frequency response of renal vasculature in congestive heart failure.

  American journal of physiology. Heart and circulatory physiology 20031101

• Effect of losartan on renal microvasculature during chronic inhibition of nitric oxide visualized by micro-CT.

  American journal of physiology. Renal physiology 20031101

• Angiotensin II mediates LDL-induced superoxide generation in mesangial cells.

  American journal of physiology. Renal physiology 20031101

• Responses to GABA-A receptor blockade in the hypothalamic PVN are attenuated by local AT1 receptor antagonism.

  American journal of physiology. Regulatory, integrative and comparative physiology 20031101

• PI3-kinase inhibitors abolish the enhanced chronotropic effects of angiotensin II in spontaneously hypertensive rat brain neurons.

  Journal of neurophysiology 20031101

• Angiotensin II accelerates functional recovery in the rat sciatic nerve in vivo: role of the AT2 receptor and the transcription factor NF-kappaB.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031101

• Effect of the single CYP2C9*3 allele on pharmacokinetics and pharmacodynamics of losartan in healthy Japanese subjects.

  European journal of clinical pharmacology 20031101

• Angiotensin II dependent testicular fibrosis and effects on spermatogenesis after vasectomy in the rat.

  The Journal of urology 20031101

• Modulation of angiotensin II-mediated signalling by heparan sulphate glycosaminoglycans.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20031101

• Trials in isolated systolic hypertension: an update.

  Current cardiology reports 20031101

• Angiotensin-converting enzyme inhibitors and stroke prevention: what about the influence of atrial fibrillation and antithrombotic therapy?

  Stroke 20031101

• Synthesis and antagonistic activity of four new 2-alkyl-N-biphenyl fused imidazoles on angiotensin II receptors.

  Farmaco (Societa chimica italiana : 1989) 20031101

• Effects of losartan combined with exercise training in spontaneously hypertensive rats.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20031101

• Influence of losartan and atenolol on memory function in very elderly hypertensive patients.

  Journal of human hypertension 20031101

• Prostacyclin and thromboxane A2 production in nitric oxide-deficient hypertension in vivo. Effects of high calcium diet and angiotensin receptor blockade.

  Prostaglandins, leukotrienes, and essential fatty acids 20031101

• Differential regulation of in vivo angiogenesis by angiotensin II receptors.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031101

• The A1166C polymorphism of the AT1 receptor gene is associated with collagen type I synthesis and myocardial stiffness in hypertensives.

  Journal of hypertension 20031101

• Angiotensin I-converting enzyme is expressed by erythropoietic cells of normal and myeloproliferative bone marrow.

  British journal of haematology 20031101

• Effects of the angiotensin II subtype 1 receptor antagonist losartan on functional recovery of isolated rat hearts undergoing global myocardial ischemia-reperfusion.

  Pharmacotherapy 20031101

• Are there benefits to specific antihypertensive drug therapy?

  American journal of hypertension 20031101

• Recommendations for the management of special populations: renal disease in diabetes.

  American journal of hypertension 20031101

• Recommendations for the management of special populations: racial and ethnic populations.

  American journal of hypertension 20031101

• Acute haemodynamic effects of losartan in anaesthetized cirrhotic rats.

  European journal of clinical investigation 20031101

• Effects of losartan on pressure overload-induced cardiac gene expression profiling in rats.

  Clinical and experimental pharmacology & physiology 20031101

• Losartan induced fetal toxicity.

  Indian journal of pediatrics 20031101

• Differing anti-proteinuric action of candesartan and losartan in chronic renal disease.

  Hypertension research : official journal of the Japanese Society of Hypertension 20031101

• [Clinical observation of 41 cases of senile ischemic heart disease treated by losarton, carvadilol and Shenmai Injection].

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20031101

• [The role of brain AT1 receptor in renal sodium and water excretion and the change of TH-IR in hypothalamus].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20031101

• [Dosage equivalents of AT1-receptor antagonists available in Germany].

  Deutsche medizinische Wochenschrift (1946) 20031031

• LIFE: losartan versus atenolol.

  Lancet (London, England) 20031025

• LIFE: losartan versus atenolol.

  Lancet (London, England) 20031025

• Modulation of delayed rectifier potassium current by angiotensin II in CATH.a cells.

  Biochemical and biophysical research communications 20031024

• Angiotensin II induction of AP-1 in neurons requires stimulation of PI3-K and JNK.

  Biochemical and biophysical research communications 20031017

• Sarcosine1,glycine8 angiotensin II is an AT1 angiotensin II receptor subtype selective antagonist.

  Regulatory peptides 20031015

• Effects of captopril and losartan on lipid peroxidation, protein oxidation and nitric oxide release in diabetic rat kidney.

  Prostaglandins, leukotrienes, and essential fatty acids 20031001

• Antiproteinuric effects of enalapril and losartan: a pilot study.

  Pediatric nephrology (Berlin, Germany) 20031001

• PKC-zeta is required for angiotensin II-induced activation of ERK and synthesis of C-FOS in MCF-7 cells.

  Journal of cellular physiology 20031001

• Reducing CVD risk in type 2 DM.

  Current diabetes reports 20031001

• The antiproteinuric effect of losartan is systemic blood pressure dependent.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20031001

• Increased plasma concentration of natriuretic peptides by selective beta1-blocker bisoprolol.

  Journal of cardiovascular pharmacology 20031001

• Facilitation of renal autoregulation by angiotensin II is mediated through modulation of nitric oxide.

  Acta physiologica Scandinavica 20031001

• Spironolactone prevents cardiac collagen proliferation after myocardial infarction in rats.

  Clinical and experimental pharmacology & physiology 20031001

• Angiotensin-converting enzyme inhibitors: optimal management of cardiovascular risk.

  The American journal of cardiology 20031001

• The receptors and role of angiotensin II in knee joint blood flow regulation and role of nitric oxide in modulation of their function.

  Microcirculation (New York, N.Y. : 1994) 20031001

• Choice of treatment: outcomes and treatment goals.

  American heart journal 20031001

• Of millimeterology and cannibalism: comparative antihypertensive efficacy of angiotensin receptor blockers.

  American heart journal 20031001

• Effects of losartan and enalapril at different doses on cardiac and renal interstitial matrix in spontaneously hypertensive rats.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20031001

• A comparison of initial treatment with losartan/HCTZ versus losartan monotherapy in chinese patients with mild to moderate essential hypertension.

  International journal of clinical practice 20031001

• The preventive effect of captopril or enalapril on reperfusion injury of the kidney of rats is independent of angiotensin II AT1 receptors.

  Fundamental & clinical pharmacology 20031001

• Effects of V1 and angiotensin receptor subtypes of the paraventricular nucleus on the water intake induced by vasopressin injected into the lateral septal area.

  Brain research bulletin 20030930

• [Is type-2 diabetes mellitus preventable?].

  Orvosi hetilap 20030928

• Connective tissue growth factor is a mediator of angiotensin II-induced fibrosis.

  Circulation 20030923

• [Cardiologic and diabetologic aspects of therapy with angiotensin receptor blocking agents].

  Orvosi hetilap 20030921

• Development and validation of an UV derivative spectrophotometric determination of Losartan potassium in tablets.

  Journal of pharmaceutical and biomedical analysis 20030919

• Simultaneous determination of losartan and EXP3174 in human plasma and urine utilizing liquid chromatography/tandem mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20030915

• High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase.

  Circulation 20030909

• [Theoretical background of angiotensin II receptor blockade and its features in clinical pharmacology].

  Orvosi hetilap 20030907

• Angiotensin II type 2 receptor inhibits vascular endothelial growth factor-induced migration and in vitro tube formation of human endothelial cells.

  Circulation research 20030905

• Role of prostaglandin, endothelin and sympathetic nervous system on the L-NAME-induced pressor responses in spontaneously hypertensive rats.

  Brain research 20030905

• Angiotensin II modulates nitric oxide-induced cardiac fibroblast apoptosis by activation of AKT/PKB.

  American journal of physiology. Heart and circulatory physiology 20030901

• Losartan reduces cardiovascular morbidity and mortality in patients with hypertension and left ventricular hypertrophy.

  Current atherosclerosis reports 20030901

• New evidence on the importance of the renin-angiotensin system in the treatment of higher-risk patients with hypertension.

  Journal of hypertension 20030901

• Brain nitric oxide synthase activity in spontaneously hypertensive rats during the development of hypertension.

  Journal of hypertension 20030901

• Antiproteinuric efficacy of losartan in comparison with amlodipine in non-diabetic proteinuric renal diseases: a double-blind, randomized clinical trial.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030901

• Pharmacoeconomic aspects of losartan treatment to delay progression of renal disease in patients with Type 2 diabetes.

  Expert opinion on pharmacotherapy 20030901

• Congestive heart failure: guidelines for the primary care physician.

  The Mount Sinai journal of medicine, New York 20030901

• [Effect of losartan and Nitrendipine on fibrinolytic system in patient with essential hypertensim].

  Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20030901

• [Combination therapy with losartan and fosinopril for early diabetic nephropathy].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030901

• [Serum TIMP-1 concentration in patients with chronic glomerulonephritis and the effect of losartan].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030901

• NADPH oxidase and enhanced superoxide generation in intrauterine undernourished rats: involvement of the renin-angiotensin system.

  Cardiovascular research 20030901

• [Angiotensin receptor blockers in chronic heart failure].

  Nihon rinsho. Japanese journal of clinical medicine 20030901

• Acute renal failure secondary to angiotensin II receptor blockade in a patient with bilateral renal artery stenosis.

  Pharmacotherapy 20030901

• Patients with steroid refractory acute vascular rejection develop agonistic antibodies targeting angiotensin II type 1 receptor.

  Transplantation proceedings 20030901

• Insulin and losartan reduce proteinuria and renal hypertrophy in the pregnant diabetic rat.

  The Journal of laboratory and clinical medicine 20030901

• Antioxidant enzyme gene expression in congestive heart failure following myocardial infarction.

  Molecular and cellular biochemistry 20030901

• Losartan inhibits myosin isoform shift after myocardial infarction in rats.

  Molecular and cellular biochemistry 20030901

• [Effect of angiotensin II on tissue factor expression in human peripheral blood monocytes and its mechanisms].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20030901

• Interim evidence of the renoprotective effect of the angiotensin II receptor antagonist losartan versus the calcium channel blocker amlodipine in patients with chronic kidney disease and hypertension: a report of the Japanese Losartan Therapy Intended for Global Renal Protection in Hypertensive Patients (JLIGHT) Study.

  Clinical and experimental nephrology 20030901

• Renal vascular responsiveness to angiotensin II at an early stage of diabetes: interaction between intrarenal noradrenergic and renin-angiotensin systems.

  Acta diabetologica 20030901

• [ACE inhibitors and/or sartans in heart failure: is there a difference?].

  Revue medicale de Bruxelles 20030901

• [Angiotensin-converting enzyme inhibitors and/or angiotensin II receptors antagonists in the treatment of arterial hypertension].

  Revue medicale de Bruxelles 20030901

• The role of Ang (1-7) in mediating the chronic hypotensive effects of losartan in normal rats.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20030901

• Effects of ACE inhibition and AT1-receptor antagonism on endothelial function and insulin sensitivity in essential hypertensive patients.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20030901

• Losartan's molecular basis of interaction with membranes and AT1 receptor.

  Chemistry and physics of lipids 20030901

• Effect of losartan on albuminuria, peripheral and autonomic neuropathy in normotensive microalbuminuric type 2 diabetics.

  Neurology India 20030901

• Chronic administration of losartan reverses cardiovascular changes in hypertensive fructose-fed rats.

  Cellular and molecular biology (Noisy-le-Grand, France) 20030901

• Angiotensin receptor blocker as adjunctive therapy for rhythm control in atrial fibrillation: results of the irbesartan-amiodarone trial.

  Cardiac electrophysiology review 20030901

• Acute myocardial infarction caused by coronary artery dissection following blunt chest trauma.

  Yonsei medical journal 20030830

• Might losartan reduce sudden cardiac death in diabetic patients with hypertension?

  Lancet (London, England) 20030823

• Effect of losartan on sudden cardiac death in people with diabetes: data from the LIFE study.

  Lancet (London, England) 20030823

• Further studies on the effect of intracellular angiotensins on heart cell communication: on the role of endogenous angiotensin II.

  Regulatory peptides 20030815

• Regression of electrocardiographic left ventricular hypertrophy by losartan versus atenolol: The Losartan Intervention for Endpoint reduction in Hypertension (LIFE) Study.

  Circulation 20030812

• Activation and functional significance of the renin-angiotensin system in mice with cardiac restricted overexpression of tumor necrosis factor.

  Circulation 20030805

• Effects of losartan or atenolol in hypertensive patients without clinically evident vascular disease: a substudy of the LIFE randomized trial.

  Annals of internal medicine 20030805

• Summaries for patients. Benefits of losartan in patients with hypertension and left ventricular hypertrophy but no vascular disease.

  Annals of internal medicine 20030805

• Angiotensin II activates extracellular signal regulated kinases via protein kinase C and epidermal growth factor receptor in breast cancer cells.

  Journal of cellular physiology 20030801

• Angiotensin II-induced inotropism requires an endocardial endothelium-nitric oxide mechanism in the in-vitro heart of Anguilla anguilla.

  The Journal of experimental biology 20030801

• Increased pressor sensitivity to chronic nitric oxide deficiency in hyperthyroid rats.

  Hypertension (Dallas, Tex. : 1979) 20030801

• Lessons from trials in hypertensive type 2 diabetic patients.

  Current hypertension reports 20030801

• Trials in isolated systolic hypertension: an update.

  Current hypertension reports 20030801

• Effects of the combination of an angiotensin II antagonist with an HMG-CoA reductase inhibitor in experimental diabetes.

  Kidney international 20030801

• Effects of losartan on diabetic maculopathy in type 2 diabetic patients: a randomized, double-masked study.

  Journal of internal medicine 20030801

• Telmisartan vs losartan plus hydrochlorothiazide in the treatment of mild-to-moderate essential hypertension--a randomised ABPM study.

  Journal of human hypertension 20030801

• Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade.

  British journal of pharmacology 20030801

• A screening study on the liability of eight different female sex steroids to inhibit CYP2C9, 2C19 and 3A4 activities in human liver microsomes.

  Pharmacology & toxicology 20030801

• The OPTIMAAL study, not so optimal: the lessons of LIFE, RENAAL and IDNT.

  The Canadian journal of cardiology 20030801

• Betaxolol-induced deterioration of asthma and a pharmacodynamic analysis based on beta-receptor occupancy.

  International journal of clinical pharmacology and therapeutics 20030801

• [Inhibitory effect of angiotensin II receptor antagonist on the contraction and growth of hepatic stellate cells].

  The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20030801

• [Effect of ligustrazine on proliferative glomerulonephritis].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20030801

• [Effect of ACE-I and AT-1 receptor blocker on the progression of CCl(4)-inducing rat hepatic fibrogenesis].

  Zhonghua yi xue za zhi 20030725

• Effect of losartan on microalbuminuria in normotensive patients with type 2 diabetes mellitus. A randomized clinical trial.

  Annals of internal medicine 20030715

• Summaries for patients. The blood pressure drug losartan appears to benefit the kidneys of people with type 2 diabetes who do not have high blood pressure.

  Annals of internal medicine 20030715

• Effects of blood pressure level on progression of diabetic nephropathy: results from the RENAAL study.

  Archives of internal medicine 20030714

• Angiotensin II and III microinjections into the zona incerta influence drinking behavior.

  Brain research 20030711

• Role of angiotensin II under prolonged increased intraabdominal pressure (IAP) in pigs.

  Surgical endoscopy 20030701

• Effect of ANG II type I receptor antagonist and ACE inhibitor on vitamin D receptor-null mice.

  American journal of physiology. Regulatory, integrative and comparative physiology 20030701

• Ureteral function is modulated by a local renin-angiotensin system.

  The Journal of urology 20030701

• NADPH oxidase-derived superoxide anion mediates angiotensin II-induced cardiac hypertrophy.

  Journal of molecular and cellular cardiology 20030701

• AT1 and AT2 receptors in human glomerular endothelial cells at different passages.

  Microvascular research 20030701

• Functional comparison of the antagonistic properties of some Angiotensin II type 1 receptor blockers on the contraction elicited by Angiotensin II and thromboxane A2 on human saphenous veins.

  Journal of cardiovascular pharmacology 20030701

• ACE inhibitors and AT-1-receptor antagonists COOPERATE in non-diabetic renal disease.

  Expert opinion on pharmacotherapy 20030701

• Combined converting enzyme inhibition and angiotensin receptor blockade reduce proteinuria greater than converting enzyme inhibition alone: insights into mechanism.

  Clinical nephrology 20030701

• Long-term antiproteinuric and renoprotective efficacy and safety of losartan in children with proteinuria.

  The Journal of pediatrics 20030701

• Effect of chronic treatment with losartan on streptozotocin-induced renal dysfunction.

  Molecular and cellular biochemistry 20030701

• The telmisartan programme of research tO show Telmisartan End-organ proteCTION (PROTECTION) programme.

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20030701

• Cardiology patient page. Angiotensin receptor blockers.

  Circulation 20030624

• Angioedema and AT1 receptor blockers: proceed with caution.

  Archives of internal medicine 20030623

• Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615

• [Fast-acting sartan. High blood pressure therapy without long waiting time].

  MMW Fortschritte der Medizin 20030612

• Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites.

  Journal of medicinal chemistry 20030605

• ACE and non-ACE mediated effect of angiotensin I on intracellular calcium mobilization in rat glomerular arterioles.

  American journal of physiology. Heart and circulatory physiology 20030601

• Chronic effects of angiotensin-converting enzyme inhibition on kinin receptor binding sites in the rat spinal cord.

  American journal of physiology. Heart and circulatory physiology 20030601

• Angiotensin II type 1 receptor antagonists inhibit basal as well as low-density lipoprotein and platelet-activating factor-stimulated human monocyte chemoattractant protein-1.

  The Journal of pharmacology and experimental therapeutics 20030601

• Towards the understanding of the local hematopoietic bone marrow renin-angiotensin system.

  The international journal of biochemistry & cell biology 20030601

• Effect of angiotensin AT2 receptor stimulation on vascular cyclic GMP production in normotensive Wistar Kyoto rats.

  The international journal of biochemistry & cell biology 20030601

• Human renal fibroblasts derived from normal and fibrotic kidneys show differences in increase of extracellular matrix synthesis and cell proliferation upon angiotensin II exposure.

  Pflugers Archiv : European journal of physiology 20030601

• Analysis of the role of the SA gene in blood pressure regulation by gene targeting.

  Hypertension (Dallas, Tex. : 1979) 20030601

• Enalapril and losartan attenuate mitochondrial dysfunction in aged rats.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030601

• Optimizing target-organ protection in patients with diabetes mellitus: angiotensin-converting enzyme inhibitors or angiotensin receptor blockers?

  Current hypertension reports 20030601

• Nitric oxide synthesis influences the renal vascular response to heme oxygenase inhibition.

  American journal of physiology. Renal physiology 20030601

• AT1 receptor blockade improves vasorelaxation in experimental renal failure.

  Hypertension (Dallas, Tex. : 1979) 20030601

• Hyperuricemia and gout.

  Current rheumatology reports 20030601

• Effect of losartan and amlodipine on proteinuria and transforming growth factor-beta1 in patients with IgA nephropathy.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030601

• Angiotensin II-induced ionic currents and signalling pathways in submandibular ganglion neurons.

  Archives of oral biology 20030601

• Fenofibrate and losartan.

  Annals of the rheumatic diseases 20030601

• Effects of combination treatment using anti-hyperuricaemic agents with fenofibrate and/or losartan on uric acid metabolism.

  Annals of the rheumatic diseases 20030601

• AngRem104, an angiotensin II-induced novel upregulated gene in human mesangial cells, is potentially involved in the regulation of fibronectin expression.

  Journal of the American Society of Nephrology : JASN 20030601

• Oxidized LDL and its compound lysophosphatidylcholine potentiate AngII-induced vasoconstriction by stimulation of RhoA.

  Journal of the American Society of Nephrology : JASN 20030601

• Pulmonary absorption rate and bioavailability of drugs in vivo in rats: structure-absorption relationships and physicochemical profiling of inhaled drugs.

  Journal of pharmaceutical sciences 20030601

• Prospective evaluation comparing the effects of enalapril and losartan in left ventricular remodeling after acute myocardial infarction.

  American heart journal 20030601

• Effect of amlodipine, quinapril, and losartan on pulse wave velocity and plasma collagen markers in patients with mild-to-moderate arterial hypertension.

  American journal of hypertension 20030601

• ACE inhibition or angiotensin receptor blockade: which should we use in diabetic patients?

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20030601

• Biphasic effects of angiotensin (1-7) and its interactions with angiotensin II in rat aorta.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20030601

• 'A la carte' treatment of portal hypertension or just 'hors d'oeuvres'.

  Gastroenterology 20030601

• The Karolinska cocktail for phenotyping of five human cytochrome P450 enzymes.

  Clinical pharmacology and therapeutics 20030601

• Adding angiotensin II type 1 receptor blockade to angiotensin-converting enzyme inhibition limits myocyte remodeling after myocardial infarction.

  Journal of cardiac failure 20030601

• Pharmacokinetics, safety, and antihypertensive efficacy of losartan in combination with hydrochlorothiazide in hypertensive patients with renal impairment.

  Journal of clinical pharmacology 20030601

• Does losartan work after all?

  The American journal of gastroenterology 20030601

• Portal pressure response to losartan compared with propranolol in patients with cirrhosis.

  The American journal of gastroenterology 20030601

• Losartan and E3174 pharmacokinetics in cytochrome P450 2C9*1/*1, *1/*2, and *1/*3 individuals.

  Pharmacotherapy 20030601

• Chronic ethanol ingestion increases expression of the angiotensin II type 2 (AT2) receptor and enhances tumor necrosis factor-alpha- and angiotensin II-induced cytotoxicity via AT2 signaling in rat alveolar epithelial cells.

  Alcoholism, clinical and experimental research 20030601

• Effects of angiotensin II and its receptor antagonists on motor activity and anxiety in rats.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20030601

• A case of exercise-induced acute renal failure in a patient with idiopathic renal hypouricemia developed during antihypertensive therapy with losartan and trichlormethiazide.

  Hypertension research : official journal of the Japanese Society of Hypertension 20030601

• Effects of a therapy with losartan and quinaprilat on the progression of chronic renal failure in rats after a single dose of uranyl nitrate or 5/6 nephrectomy.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030601

• [Losartan downregulates the expression of transforming growth factor beta type I and type II receptors in kidney of diabetic rat].

  Zhonghua nei ke za zhi 20030601

• Comparison of telmisartan versus losartan: meta-analysis of titration-to-response studies.

  Blood pressure monitoring 20030601

• [AT1 receptor autoantibodies and essential hypertension].

  Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20030601

• Bayesian cost-effectiveness analysis based on the persistence with antihypertensive treatment.

  Expert review of pharmacoeconomics & outcomes research 20030601

• Debate: angiotensin-converting enzyme inhibitors versus angiotensin II receptor blockers--a gap in evidence-based medicine.

  The American journal of cardiology 20030522

• Enhanced angiotensin-mediated responses in the nucleus tractus solitarii of spontaneously hypertensive rats.

  Brain research bulletin 20030515

• [Therapy of hypertension in patients with atrial fibrillation. Sartan is superior to beta-blocker].

  MMW Fortschritte der Medizin 20030508

• [Diurnal blood pressure control in the optimal treatment of hypertension].

  Orvosi hetilap 20030504

• Effect of blockade of endogenous angiotensin II on baroreflex function in conscious diabetic rats.

  American journal of physiology. Heart and circulatory physiology 20030501

• AT1 receptors in the RVLM mediate pressor responses to emotional stress in rabbits.

  Hypertension (Dallas, Tex. : 1979) 20030501

• Angiotensin II AT1 receptor antagonism prevents detrimental renal actions of acute diuretic therapy in human heart failure.

  American journal of physiology. Renal physiology 20030501

• Expression and modulation of steroidogenic acute regulatory protein messenger ribonucleic acid in rat cardiocytes and after myocardial infarction.

  Endocrinology 20030501

• Circulatory effects of angiotensin II during anaesthesia, evaluated by real-time spectral analysis.

  Acta anaesthesiologica Scandinavica 20030501

• Regression of renal vascular and glomerular fibrosis: role of angiotensin II receptor antagonism and matrix metalloproteinases.

  Journal of the American Society of Nephrology : JASN 20030501

• Role of the renin-angiotensin system in the compensation of quinpirole-induced blood pressure decrease.

  Naunyn-Schmiedeberg's archives of pharmacology 20030501

• Enalaprilat, losartan and LU 135252 in coronary blood flow regulation.

  European journal of clinical investigation 20030501

• Trough-to-peak ratio, smoothness index and morning-to-evening ratio: why, which and when?

  Journal of hypertension 20030501

• Comparison of the smoothness index, the trough : peak ratio and the morning : evening ratio in assessing the features of the antihypertensive drug effect.

  Journal of hypertension 20030501

• NAD(P)H oxidase activation by angiotensin II is dependent on p42/44 ERK-MAPK pathway activation in rat's vascular smooth muscle cells.

  Journal of hypertension 20030501

• Analysis of metabolic parameters as predictors of risk in the RENAAL study.

  Diabetes care 20030501

• Long-term renoprotective effects of losartan in diabetic nephropathy: interaction with ACE insertion/deletion genotype?

  Diabetes care 20030501

• Uveal effusion and angle-closure glaucoma in primary pulmonary hypertension.

  American journal of ophthalmology 20030501

• Angiotensin AT1 receptor antagonist losartan and the defence reaction in the anaesthetised rat. Effect on the carotid chemoreflex.

  Experimental physiology 20030501

• Activation of the renin-angiotensin system contributes to the peripheral vasoconstriction reflexly caused by stomach distension in anaesthetized pigs.

  Experimental physiology 20030501

• Implications of the LIFE trial.

  Expert opinion on investigational drugs 20030501

• The DASH diet enhances the blood pressure response to losartan in hypertensive patients.

  American journal of hypertension 20030501

• Effect of losartan on oxidative stress-induced hypertension in Sprague-Dawley rats.

  American journal of hypertension 20030501

• [Treatment of heart failure based on large-scale clinical trials: renin-angiotensin system antagonists and beta-blockers].

  Nihon rinsho. Japanese journal of clinical medicine 20030501

• [Treatment for diastolic failure].

  Nihon rinsho. Japanese journal of clinical medicine 20030501

• What did we learn from the OPTIMAAL trial? What can we expect from VALIANT?

  American heart journal 20030501

• Relation of QT interval and QT dispersion to regression of echocardiographic and electrocardiographic left ventricular hypertrophy in hypertensive patients: the Losartan Intervention For Endpoint Reduction (LIFE) study.

  American heart journal 20030501

• Efficacy and tolerability of fixed-dose combinations of telmisartan plus HCTZ compared with losartan plus HCTZ in patients with essential hypertension.

  International journal of clinical practice 20030501

• Comparison of the blood pressure-lowering effects and tolerability of Losartan- and Amlodipine-based regimens in patients with isolated systolic hypertension.

  Clinical therapeutics 20030501

• Renin, angiotensin, sodium and organ damage.

  Hypertension research : official journal of the Japanese Society of Hypertension 20030501

• Comparison of the efficacy, safety and tolerability of telmisartan with losartan in Indian patients with mild to moderate hypertension: a pilot study.

  Journal of the Indian Medical Association 20030501

• ACE-inhibition and angiotensin II receptor blockers in chronic heart failure: pathophysiological consideration of the unresolved battle.

  Cardiovascular drugs and therapy 20030501

• [Relationship between regression of hypertensive left ventricular hypertrophy and improvement of coronary flow reserve].

  Zhonghua yi xue za zhi 20030425

• Caspase-dependent cell death mediates the early phase of aortic hypertrophy regression in losartan-treated spontaneously hypertensive rats.

  Circulation research 20030418

• The vascular response to the K+ channel inhibitor 4-aminopyridine in hypertensive rats.

  European journal of pharmacology 20030418

• Angiotensin-converting enzyme inhibition but not angiotensin II type 1 receptor antagonism augments coronary release of tissue plasminogen activator in hypertensive patients.

  Journal of the American College of Cardiology 20030416

• Vasopeptidase inhibitor omapatrilat induces profound insulin sensitization and increases myocardial glucose uptake in Zucker fatty rats: Studies comparing a vasopeptidase inhibitor, angiotensin-converting enzyme inhibitor, and angiotensin II type I receptor blocker.

  Circulation 20030415

• Peptide and nonpeptide antagonist interaction with constitutively active human AT1 receptors.

  Biochemical pharmacology 20030415

• A two-state model of antagonist-AT1 receptor interaction: further support by binding studies at low temperature.

  Biochemical pharmacology 20030415

• [From risk factors to symptomatic coronary artery disease. Update cardiology 2001/2002--part I].

  Medizinische Klinik (Munich, Germany : 1983) 20030415

• [AT-1 blockers are different in their effects. The forgetful patients begin to notice it especially].

  MMW Fortschritte der Medizin 20030410

• C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle.

  Circulation 20030408

• Localization of AT(2) receptors in the nucleus of the solitary tract of spontaneously hypertensive and Wistar Kyoto rats using [125I] CGP42112: upregulation of a non-angiotensin II binding site following unilateral nodose ganglionectomy.

  Brain research 20030404

• Efficacy and tolerability of eplerenone and losartan in hypertensive black and white patients.

  Journal of the American College of Cardiology 20030402

• Hypertension, angiotensin II, aldosterone, and race.

  Journal of the American College of Cardiology 20030402

• Proinflammatory effects of oxidative stress in chronic kidney disease: role of additional angiotensin II blockade.

  American journal of physiology. Renal physiology 20030401

• Cysteinyl leukotriene-dependent [Ca2+]i responses to angiotensin II in cardiomyocytes.

  American journal of physiology. Heart and circulatory physiology 20030401

• ANG II is involved in the LPS-induced production of proinflammatory cytokines in dehydrated rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20030401

• Chronic angiotensin II infusion attenuates the renal sympathoinhibitory response to acute volume expansion.

  American journal of physiology. Regulatory, integrative and comparative physiology 20030401

• The risk of developing end-stage renal disease in patients with type 2 diabetes and nephropathy: the RENAAL study.

  Kidney international 20030401

• Pulse pressure/stroke index and left ventricular geometry and function: the LIFE Study.

  Journal of hypertension 20030401

• Persistent lowering of arterial pressure after continuous and intermittent therapy.

  Journal of hypertension 20030401

• Central nervous system blockade by peripheral administration of AT1 receptor blockers.

  Journal of cardiovascular pharmacology 20030401

• Effects of angiotensin II on vascular endothelial cells: formation of receptor-mediated reactive nitrogen species.

  Biochemical pharmacology 20030401

• AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase.

  Circulation 20030401

• Conformational and biological studies for a pair of novel synthetic AT1 antagonists: stereoelectronic requirements for antihypertensive efficacy.

  Journal of pharmaceutical and biomedical analysis 20030401

• [Scleroderma renal crisis following withdrawal of therapy with losartan].

  La Revue de medecine interne 20030401

• Vasoactive effects of erythropoietin on human placental blood vessels in vitro.

  American journal of obstetrics and gynecology 20030401

• Characterization of a fluorescent conjugate of the rabbit angiotensin AT(1) receptor.

  British journal of pharmacology 20030401

• Hypertension due to blockade of adenosine receptors.

  Pharmacology & toxicology 20030401

• Influence of angiotensin II receptor subtypes of the paraventricular nucleus on the physiological responses induced by angiotensin II injection into the medial septal area.

  Arquivos brasileiros de cardiologia 20030401

• Differential anxiolytic effect of enalapril and losartan in normotensive and renal hypertensive rats.

  Physiology & behavior 20030401

• An analysis of cholesterol control and statin use in the Losartan Intervention for Endpoint Reduction in Hypertension Study.

  Clinical therapeutics 20030401

• Effect of high glucose, angiotensin II and receptor antagonist Losartan on the expression of connective tissue growth factor in cultured mesangial cells.

  Chinese medical journal 20030401

• [Protective effect of angiotensin II receptor blockage on rats with experimental diabetes nephropathy in early stage].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20030401

• Losartan and atenolol on hypertension induced by adenosine receptor blockade.

  Autonomic & autacoid pharmacology 20030401

• Impact of asymptomatic hypertension on left ventricular functions.

  Indian journal of physiology and pharmacology 20030401

• Angiotensin II-induced release of oxytocin: interaction with norepinephrine and role in lactation.

  Regulatory peptides 20030328

• The effects of sarmesin, an Angiotensin II analogue on seizure susceptibility, memory retention and nociception.

  Regulatory peptides 20030328

• [Stimulation of neuropeptide Y on heat shock protein expression in renal vascular smooth muscle and the inhibition thereon by losartan].

  Zhonghua yi xue za zhi 20030325

• The COOPERATE trial.

  Lancet (London, England) 20030322

• The COOPERATE trial.

  Lancet (London, England) 20030322

• Down-regulation of bradykinin B2-receptor mRNA in the heart in pressure-overload cardiac hypertrophy in the rat.

  Biochemical pharmacology 20030315

• Involvement of calcitonin gene-related peptide in the depressor effects of losartan and perindopril in rats.

  European journal of pharmacology 20030307

• ANG II AT2 receptor modulates AT1 receptor-mediated descending vasa recta endothelial Ca2+ signaling.

  American journal of physiology. Heart and circulatory physiology 20030301

• Hypoxia and high glucose upregulate AT1 receptor expression and potentiate ANG II-induced proliferation in VSM cells.

  American journal of physiology. Heart and circulatory physiology 20030301

• Conversion of brain angiotensin II to angiotensin III is critical for pressor response in rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20030301

• Control of dendritic cell differentiation by angiotensin II.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030301

• Thromboxane synthase and TP receptor mRNA in rat kidney and brain: effects of salt intake and ANG II.

  American journal of physiology. Renal physiology 20030301

• A favourable outcome using oral prednisolone and losartan only in a patient with ANCA-related glomerulonephritis: a discrepancy between histological activity and MPO-ANCA.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030301

• Efficacy of losartan in patients with primary focal segmental glomerulosclerosis resistant to immunosuppressive treatment.

  Journal of internal medicine 20030301

• Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production.

  Diabetes 20030301

• Central angiotensin modulation of baroreflex control of renal sympathetic nerve activity in the rat: influence of dietary sodium.

  Acta physiologica Scandinavica 20030301

• Losartan reduces the costs associated with diabetic end-stage renal disease: the RENAAL study economic evaluation.

  Diabetes care 20030301

• Role of the angiotensin II system in regulation of ovulation and blood flow in the rat ovary.

  Reproduction (Cambridge, England) 20030301

• Recent advances in management of type 2 diabetes and nephropathy: lessons from the RENAAL study.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20030301

• ACE inhibitors or AT-1 antagonists - which is OPTIMAAL after acute myocardial infarction?

  Expert opinion on pharmacotherapy 20030301

• Left ventricular mass regression in the LIFE study: effect of previous antihypertensive treatment.

  American journal of hypertension 20030301

• Role of the subfornical organ in the chronic hypotensive response to losartan in normal rats.

  Hypertension (Dallas, Tex. : 1979) 20030301

• Angiotensin II regulation of AT1 and D3 dopamine receptors in renal proximal tubule cells of SHR.

  Hypertension (Dallas, Tex. : 1979) 20030301

• The role of endogenous angiotensin II in ischaemia, reperfusion and preconditioning of the isolated rat heart.

  Pflugers Archiv : European journal of physiology 20030301

• Does losartan prevent cerebral edema? A preliminary study using a vascular compartment model.

  Medical science monitor : international medical journal of experimental and clinical research 20030301

• The LIFE study: the straw that should break the camel's back.

  European heart journal 20030301

• Angiotensin II subtype AT1 receptor blockade prevents hypertension and renal insufficiency induced by chronic NO-synthase inhibition in rats.

  Naunyn-Schmiedeberg's archives of pharmacology 20030301

• Effects of angiotensin II and losartan on the growth and proliferation of hepatic stellate cells.

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030301

• Screening and identification of the up-regulated genes in human mesangial cells exposed to angiotensin II.

  Hypertension research : official journal of the Japanese Society of Hypertension 20030301

• Cardiac myofibroblasts: a novel source of vascular endothelial growth factor (VEGF) and its receptors Flt-1 and KDR.

  Journal of molecular and cellular cardiology 20030301

• The effect of high dose losartan on erythropoietin resistance in patients undergoing haemodialysis.

  Panminerva medica 20030301

• Comparative effects of aspirin with ACE inhibitor or angiotensin receptor blocker on myocardial infarction and vascular function.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20030301

• [Reduction of cardiovascular events with lorsartan? The LIFE Study].

  Der Internist 20030301

• Characterization of angiotensin-(1-7) receptor subtype in mesenteric arteries.

  Peptides 20030301

• Angiotensin II and its receptors in human endocardial endothelial cells: role in modulating intracellular calcium.

  Canadian journal of physiology and pharmacology 20030301

• Effect of losartan on insulin plasma concentrations and LPL activity in adipose tissue of hypertensive rats.

  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030301

• [Renal protective effects of specific cyclooxygenase-2 inhibitor in rats with subtotal renal ablation].

  Zhonghua nei ke za zhi 20030301

• The renin-angiotensin system: the role of inhibitors, blockers, and genetic polymorphisms in the treatment and prevention of heart failure.

  Current vascular pharmacology 20030301

• Non-peptide angiotensin II receptor antagonists: chemical feature based pharmacophore identification.

  Journal of medicinal chemistry 20030227

• [Microalbuminuria is an early marker for increased morbidity and mortality].

  Fortschritte der Medizin. Originalien 20030227

• Simultaneous determination of hydrochlorothiazide and several angiotensin-II-receptor antagonists by capillary electrophoresis.

  Journal of pharmaceutical and biomedical analysis 20030226

• Angiotensin II activates NADPH oxidase in isolated rat hearts subjected to ischaemia-reperfusion.

  European journal of pharmacology 20030221

• Divergent roles of angiotensin II AT1 and AT2 receptors in modulating coronary microvascular function.

  Circulation research 20030221

• ST-segment resolution and late (6-month) left ventricular remodeling after acute myocardial infarction.

  The American journal of cardiology 20030215

• Synergistic effects of mycophenolate mofetil and losartan in a model of chronic cyclosporine nephropathy.

  Transplantation 20030215

• Cardiovascular and renal effects of cyclooxygenase inhibition in transgenic rats harboring mouse renin-2 gene (TGR[mREN2]27).

  European journal of pharmacology 20030214

• Losartan vs atenolol in prevention of stroke and cardiovascular disease.

  JAMA 20030212

• Losartan vs atenolol in prevention of stroke and cardiovascular disease.

  JAMA 20030212

• [Therapy for hypertension associated with kidney disease].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20030210

• More on the LIFE study.

  Lancet (London, England) 20030208

• More on the LIFE study.

  Lancet (London, England) 20030208

• Iodine as a chemoselective reoxidant of TEMPO: application to the oxidation of alcohols to aldehydes and ketones.

  Organic letters 20030206

• ANG II increases TIMP-1 expression in rat aortic smooth muscle cells in vivo.

  American journal of physiology. Heart and circulatory physiology 20030201

• The novel serine protease PreR-Co promotes endothelium-independent vasorelaxation in rabbit aortic rings.

  American journal of physiology. Heart and circulatory physiology 20030201

• Angiotensin II and renal medullary blood flow in Lyon rats.

  American journal of physiology. Renal physiology 20030201

• Best bang for the buck?

  Current hypertension reports 20030201

• Enalapril and losartan reduce sympathetic hyperactivity in patients with chronic renal failure.

  Journal of the American Society of Nephrology : JASN 20030201

• Time course of the antiproteinuric and antihypertensive effect of losartan in diabetic nephropathy.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030201

• The role of blood pressure lowering before and after stroke.

  Current opinion in neurology 20030201

• Effects of angiotensin II receptor blockade versus angiotensin-converting-enzyme inhibition on ventricular remodelling following myocardial infarction in the mouse.

  Clinical science (London, England : 1979) 20030201

• Comparative effects of carvedilol and losartan alone and in combination for preventing left ventricular remodeling after acute myocardial infarction in rats.

  Circulation journal : official journal of the Japanese Circulation Society 20030201

• Angiotensin-(1-7) reduces renal angiotensin II receptors through a cyclooxygenase-dependent mechanism.

  Journal of cardiovascular pharmacology 20030201

• Increased expression of cardiac angiotensin II type 1 (AT(1)) receptors decreases myocardial microvessel density after experimental myocardial infarction.

  Cardiovascular research 20030201

• Role of angiotensin II in L-NAME-induced systemic and renal hemodynamic effects in hydrochlorothiazide-pretreated hypertensive subjects.

  Journal of hypertension 20030201

• Beneficial effect of losartan against proteinuria from the renal allograft.

  Transplantation proceedings 20030201

• Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human trophoblast cells.

  Journal of the Society for Gynecologic Investigation 20030201

• Collagenofibrotic glomerulopathy with a widespread expression of type-V collagen.

  Virchows Archiv : an international journal of pathology 20030201

• An economic evaluation of Losartan therapy in type 2 diabetic patients with nephropathy: an analysis of the RENAAL study adapted to France.

  Diabetes & metabolism 20030201

• Angiotensin II receptor types 1A, 1B, and 2 in murine neuroblastoma Neuro-2a cells.

  Journal of receptor and signal transduction research 20030201

• Agonistic autoantibodies directed against the angiotensin II AT1 receptor in patients with preeclampsia.

  Canadian journal of physiology and pharmacology 20030201

• Regulation of insulin-like growth factor-1 by the renin-angiotensin system during regression of cardiac eccentric hypertrophy through angiotensin-converting enzyme inhibitor and AT1 antagonist.

  Canadian journal of physiology and pharmacology 20030201

• Angiotensin-II-induced enhanced expression of Gi proteins is attenuated by losartan in A10 vascular smooth muscle cells: role of AT1 receptors.

  Canadian journal of physiology and pharmacology 20030201

• Inhibition of amiodarone-induced lung fibrosis but not alveolitis by angiotensin system antagonists.

  Pharmacology & toxicology 20030201

• [Effect of losartan on produce of sera autoantibodies to angiotensin II-1 receptor in renovascular hypertension rats].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20030201

• [The effect of losartan versus atenolol on cardiovascular morbidity and mortality in patients with hypertension and ECG-verified left ventricular hypertrophy in the LIFE-study].

  Ugeskrift for laeger 20030127

• [The effect of losartan versus atenolol on cardiovascular morbidity and mortality in patients with diabetes mellitus in the LIFE-study].

  Ugeskrift for laeger 20030127

• [Angiotensin 1-antagonists: primary therapeutic option in arterial hypertension, too].

  Deutsche medizinische Wochenschrift (1946) 20030124

• Food and Drug Administration: Cardiovascular and Renal Drugs Advisory Committee, 98th meeting, January 6th-7th, 2003.

  Circulation 20030121

• [Treatment of hypertension: angiotensin-II antagonists potentially better than beta-blockers in the occurrence of cardiovascular and cerebrovascular damage; the LIFE study in perspective].

  Nederlands tijdschrift voor geneeskunde 20030118

• [Losartan in isolated systolic hypertension--convincing results of a LIFE sub-group study].

  MMW Fortschritte der Medizin 20030116

• Combination treatment of angiotensin-II receptor blocker and angiotensin-converting-enzyme inhibitor in non-diabetic renal disease (COOPERATE): a randomised controlled trial.

  Lancet (London, England) 20030111

• Optimization and validation of a micellar electrokinetic chromatographic method for the analysis of several angiotensin-II-receptor antagonists.

  Journal of chromatography. A 20030110

• In vitro effect of sanguinarine alkaloid on binding of [3H]candesartan to the human angiotensin AT1 receptor.

  European journal of pharmacology 20030105

• Treatment of arteriosclerosis.

  Deutsche medizinische Wochenschrift (1946) 20030103

• Renal and intestinal handling of oxalate following oxalate loading in rats.

  American journal of nephrology 20030101

• Angiotensin II stimulates basolateral K channels in rat cortical collecting ducts.

  American journal of physiology. Renal physiology 20030101

• Impaired responsiveness of renal mechanosensory nerves in heart failure: role of endogenous angiotensin.

  American journal of physiology. Regulatory, integrative and comparative physiology 20030101

• Angiotensin receptors contribute to blood pressure homeostasis in salt-depleted SHR.

  American journal of physiology. Regulatory, integrative and comparative physiology 20030101

• Comparative cost effectiveness of angiotensin II receptor blockers in a US managed care setting: olmesartan medoxomil compared with losartan, valsartan, and irbesartan.

  PharmacoEconomics 20030101

• Outcomes of treating hypertension in the elderly: a short commentary on current issues.

  The American journal of geriatric cardiology 20030101

• Olmesartan medoxomil: the seventh angiotensin receptor antagonist.

  The Annals of pharmacotherapy 20030101

• Successful treatment of radiation nephropathy with angiotensin II blockade.

  International journal of radiation oncology, biology, physics 20030101

• The functional role of the JAK-STAT pathway in post-infarction remodeling.

  Cardiovascular research 20030101

• New strategies for prevention of ischemic stroke: the LIFE study.

  Current neurology and neuroscience reports 20030101

• Angiotensin II receptor blockade: is there truly a benefit of adding an ACE inhibitor?

  Hypertension (Dallas, Tex. : 1979) 20030101

• Modulation of angiotensin II responses in sympathetic neurons by cytosolic calcium.

  Hypertension (Dallas, Tex. : 1979) 20030101

• Echocardiographic wall motion abnormalities in hypertensive patients with electrocardiographic left ventricular hypertrophy: the LIFE Study.

  Hypertension (Dallas, Tex. : 1979) 20030101

• Reduction of oxidative stress augments natriuretic effect of furosemide in moderate heart failure.

  American heart journal 20030101

• Losartan for LIFE in hypertension with left ventricular hypertrophy?

  Expert opinion on pharmacotherapy 20030101

• Angiotensin II receptor blockade in diabetic nephropathy.

  American journal of hypertension 20030101

• Tolbutamide, flurbiprofen, and losartan as probes of CYP2C9 activity in humans.

  Journal of clinical pharmacology 20030101

• Angiotensin receptor blockers and epoetin resistance.

  Seminars in dialysis 20030101

• Resolving the composite trait of hypertension into its pharmacogenetic determinants by acute pharmacological modulation of blood pressure regulatory systems.

  Journal of molecular medicine (Berlin, Germany) 20030101

• Two good reasons for an angiotensin-II type 1 receptor blockade with losartan after cardiac transplantation: reduction of incidence and severity of transplant vasculopathy.

  Transplant international : official journal of the European Society for Organ Transplantation 20030101

• The effects of amlodipine compared to losartan in patients with mild to moderately severe hypertension.

  Journal of clinical hypertension (Greenwich, Conn.) 20030101

• Evaluation of angiotensin II receptor blockers for 24-hour blood pressure control: meta-analysis of a clinical database.

  Journal of clinical hypertension (Greenwich, Conn.) 20030101

• Losartan in diabetic nephropathy.

  Drugs 20030101

• Angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists in experimental myocarditis.

  Current pharmaceutical design 20030101

• Effect of enalapril and losartan on the events that precede diabetic nephropathy in rats.

  Diabetes/metabolism research and reviews 20030101

• [The best of clinical pharmacology in 2002].

  Archives des maladies du coeur et des vaisseaux 20030101

• Losartan was more effective than atenolol for isolated systolic hypertension and left ventricular hypertrophy.

  ACP journal club 20030101

• [Typing of hypouricemia (uric acid clearance)].

  Nihon rinsho. Japanese journal of clinical medicine 20030101

• Drugs that interrupt the renin-angiotensin system should be among the preferred initial drugs to treat hypertension.

  Journal of clinical hypertension (Greenwich, Conn.) 20030101

• QT dispersion has no prognostic value in patients with symptomatic heart failure: an ELITE II substudy.

  Pacing and clinical electrophysiology : PACE 20030101

• Flow propagation velocity is not a simple index of diastolic function in early filling. A comparative study of early diastolic strain rate and strain rate propagation, flow and flow propagation in normal and reduced diastolic function.

  Cardiovascular ultrasound 20030101

• Losartan did not differ from captopril for reducing all-cause mortality after acute myocardial infarction.

  ACP journal club 20030101

• LIFE and ARBITER.

  Preventive cardiology 20030101

• [Hemodynamics and cell membrane effects of angiotensin II receptor antagonists in treatment of hypertension].

  Likars'ka sprava 20030101

• Effects of telmisartan and losartan on left ventricular mass in mild-to-moderate hypertension. A randomized, double-blind trial.

  Cardiology 20030101

• Drug absorption from the isolated perfused rat lung--correlations with drug physicochemical properties and epithelial permeability.

  Journal of drug targeting 20030101

• Function of renal angiotensin AT2 receptors is not enhanced in Lyon hypertensive rats.

  Clinical and experimental pharmacology & physiology 20030101

• Drug interactions with angiotensin receptor blockers: a comparison with other antihypertensives.

  Drug safety 20030101

• [Blocker of angiotensin-1 receptor antagonist losartan. Part III. Experience in therapy for chronic heart failure and after acute myocardial infarction].

  Kardiologiia 20030101

• [Angiotensin I receptor antagonist losartan. Part II. Effects in arterial hypertension and diabetic nephropathy].

  Kardiologiia 20030101

• [Angiotensin1-receptor antagonist losartan. Part I. Basic clinical pharmacology].

  Kardiologiia 20030101

• [Influence of different pharmacological agents in the ex vivo proliferation of mesothelial cells obtained from the peritoneal effluent of patients treated with peritoneal dialysis].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20030101

• Effects of an angiotensin II receptor antagonist and angiotensin-converting enzyme inhibitors on burst forming units-erythroid in chronic hemodialysis patients.

  American journal of nephrology 20030101

• Effect of angiotensin II receptor blocker on plasma levels of TGF-beta 1 and interstitial fibrosis in hypertensive kidney transplant patients.

  American journal of nephrology 20030101

• Expression of angiotensin II type 1 receptor in rat hepatic stellate cells and its effects on cell growth and collagen production.

  Hormone research 20030101

• [Efficacy of losartan treatment of right ventricular cardiac insufficiency in patients with chronic obstructive bronchitis].

  Klinicheskaia meditsina 20030101

• [Influence of angiotensin I on angiogenesis in vitro in the rat].

  Archives des maladies du coeur et des vaisseaux 20030101

• Effect of treatment with losartan on cardiovascular autonomic and large sensory nerve fiber function in individuals with diabetes mellitus: a 1-year randomized, controlled trial.

  Journal of diabetes and its complications 20030101

• [LIFE study proves preventive action. With losartan to do even more against stroke].

  MMW Fortschritte der Medizin 20030101

• [Primary prevention of stroke. What helps--what does not help? The guidelines of the German Society of Neurology briefly summarized].

  MMW Fortschritte der Medizin 20030101

• [New perspectives of the use of angiotensin II receptor blocker].

  Kardiologiia 20030101

• Stroke prevention: is it possible? If so, which antihypertensive agent should be used?

  Current medical research and opinion 20030101

• Eplerenone: a selective aldosterone receptor antagonist for hypertension and heart failure.

  Heart disease (Hagerstown, Md.) 20030101

• Effect of antihypertensive agents on stellate cells during liver regeneration in rats.

  Arquivos de gastroenterologia 20030101

• The effects of peptide and nonpeptide antagonists of angiotensin II receptors on the noradrenaline uptake of different brain structures in rats with angiotensin II-induced increase of water intake.

  Acta physiologica et pharmacologica Bulgarica 20030101

• Prevention of hypertension attenuates albuminuria and renal expression of fibronectin in diabetic spontaneously hypertensive rats.

  American journal of nephrology 20030101

• [Therapeutic interchange between angiotensin II receptor blockers in institutionalized elderly patients. Implimenting a protocol].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20030101

• Ultrastructural changes in the remnant kidney (after 5/6 nephrectomy) glomerulus after losartan and atenolol treatment.

  Medicina (Kaunas, Lithuania) 20030101

• [Therapy of patients with arterial hypertension with fixed dose combination of losartan and hydrochlorothiazide. Effect on 24 hour blood pressure and left-ventricular hypertrophy].

  Kardiologiia 20030101

• Central and peripheral hemodynamic effects of losartan and in combination with hydrochlorothiazide in mild to moderate essential hypertension.

  Blood pressure 20030101

• Early and chronic captopril or Losartan therapy reduces infarct size and avoids congestive heart failure after myocardial infarction in rats.

  Archives of medical research 20030101

• Increased prevalence of left ventricular hypertrophy in hypertensive women with type 2 diabetes mellitus.

  Cardiovascular diabetology 20030101

• Effect of losartan microinjections into the NTS on the cardiovascular components of chemically evoked reflexes in a rabbit model of acute heart ischemia.

  Advances in experimental medicine and biology 20030101

• Gender-specific genetic determinants of blood pressure and organ weight: pharmacogenetic approach.

  Physiological research 20030101

• Renoprotective effects of losartan in renal transplant recipients. Results of a retrospective study.

  Nephron. Clinical practice 20030101

• [Evaluation of different approaches to the treatment of arterial hypertension: combination treatment with low dose perindopril/indapamide versus sequential treatment of stepped-dose treatment].

  Therapie 20030101

• Amlodipine and losartan: reaction to comparison.

  Journal of clinical hypertension (Greenwich, Conn.) 20030101

• [Prognostic value of elevation of plasma concentration of atrial natriuretic peptide in patients with cardiac failure. Results of a cohort study].

  Klinicheskaia meditsina 20030101

• Losartan: in the reduction of stroke risk in patients with hypertension and left ventricular hypertrophy.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101

• Effect of neutral endopeptidase inhibition on vascular response induced by exogenous angiotensin I in the isolated rat lung.

  Polish journal of pharmacology 20030101

• [Interactions between angiotensin-(1-7)and angiotensin II in isolated rat portal vein].

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20030101

• [Efficacy of losartan potassium and its combination with hydrochlorothiazide in hypertensive disease. Focus on the state of microcirculation].

  Kardiologiia 20030101

• [Regression of electrocardiographic left ventricular hypertrophy by losartan versus atenolol. Results of LIFE study].

  Kardiologiia 20030101

• Effect of angiotensin II type 1 (AT1) receptor antagonist on the endothelial dysfunction in spontaneously hypertensive rats in correlation with the nitric oxide system.

  Bratislavske lekarske listy 20030101

• A randomized study of losartan vs propranolol: Effects on hepatic and systemic hemodynamics in cirrhotic patients.

  Annals of hepatology 20030101

• Cardiovascular drugs and serum uric acid.

  Cardiovascular drugs and therapy 20030101

• Genetic basis for hypertrophic cardiomyopathy: implications for diagnosis and treatment.

  The American heart hospital journal 20030101

• Effects of losartan and delapril on the fibrinolytic system in patients with mild to moderate hypertension.

  Clinical drug investigation 20030101

• [Relationship of hypertensive microalbuminuria and endothelial and glomerular impairment].

  Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20021228

• Captopril enhances transforming growth factor (TGF)-beta1 expression in peripheral blood mononuclear cells: a mechanism independent from angiotensin converting enzyme inhibition? A study in cyclosporine-treated kidney-transplanted patients.

  Transplantation 20021227

• Absence of angiotensin II type 1 receptor in bone marrow-derived cells is detrimental in the evolution of renal fibrosis.

  The Journal of clinical investigation 20021215

• NAD(P)H oxidase-derived hydrogen peroxide mediates endothelial nitric oxide production in response to angiotensin II.

  The Journal of biological chemistry 20021213

• Tumor necrosis factor-alpha-induced AT1 receptor upregulation enhances angiotensin II-mediated cardiac fibroblast responses that favor fibrosis.

  Circulation research 20021213

• Estrogens inhibit angiotensin II-induced leukocyte-endothelial cell interactions in vivo via rapid endothelial nitric oxide synthase and cyclooxygenase activation.

  Circulation research 20021213

• The OPTIMAAL trial: losartan or captopril after acute myocardial infarction.

  Lancet (London, England) 20021207

• The OPTIMMAL trial: losartan or captopril after acute myocardial infarction.

  Lancet (London, England) 20021207

• The OPTIMMAL trial: losartan or captopril after acute myocardial infarction.

  Lancet (London, England) 20021207

• The OPTIMMAL trial: losartan or captopril after acute myocardial infarction.

  Lancet (London, England) 20021207

• The OPTIMMAL trial: losartan or captopril after acute myocardial infarction.

  Lancet (London, England) 20021207

• Optimization and validation of a capillary zone electrophoretic method for the analysis of several angiotensin-II-receptor antagonists.

  Journal of chromatography. A 20021206

• Angiotensin blockade in type 2 diabetic renal disease.

  Kidney international. Supplement 20021201

• Losartan in patients with type 2 diabetes and proteinuria: observations from the RENAAL Study.

  Kidney international. Supplement 20021201

• Losartan reduces the burden and cost of ESRD: public health implications from the RENAAL study for the European Union.

  Kidney international. Supplement 20021201

• Targeting the atherosclerotic process in clinical practice. A new look at established agents.

  Atherosclerosis 20021201

• Compliance and persistence with newer antihypertensive agents.

  Current hypertension reports 20021201

• Hypertension and insulin disorders.

  Current hypertension reports 20021201

• A comparison of AT1 angiotensin II antagonists at pre- and postjunctional angiotensin II receptors of the rat tail artery.

  Naunyn-Schmiedeberg's archives of pharmacology 20021201

• Hemodynamic and antifibrotic effects of losartan in rats with liver fibrosis and/or portal hypertension.

  Journal of hepatology 20021201

• Irbesartan substitution for valsartan or losartan in treating hypertension.

  The Annals of pharmacotherapy 20021201

• Acute pancreatitis associated with angiotensin II receptor antagonists.

  The Annals of pharmacotherapy 20021201

• Comparison of the antagonistic effects of different angiotensin II receptor blockers in human coronary arteries.

  European journal of heart failure 20021201

• Effect of angiotensin ii receptor blockade on arterial stiffness: beyond blood pressure reduction.

  American journal of hypertension 20021201

• Differential effects of antihypertensive drug therapy on arterial compliance.

  American journal of hypertension 20021201

• ACE inhibition versus angiotensin type 1 receptor antagonism: differential effects on PAI-1 over time.

  Hypertension (Dallas, Tex. : 1979) 20021201

• Long-term angiotensin II inhibition increases mitochondrial nitric oxide synthase and not antioxidant enzyme activities in rat heart.

  Journal of hypertension 20021201

• Change of left ventricular geometric pattern after 1 year of antihypertensive treatment: the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study.

  American heart journal 20021201

• Regulatory effects of salt diet on renal renin-angiotensin-aldosterone, and kallikrein-kinin systems.

  International immunopharmacology 20021201

• Effects of angiotensin converting enzyme inhibitor and angiotensin II receptor antagonist therapy in hypertensive renal transplant recipients.

  Transplantation proceedings 20021201

• Mechanical stretch-induced mitogen-activated protein kinase activation is mediated via angiotensin and endothelin systems in vascular smooth muscle cells.

  Biological & pharmaceutical bulletin 20021201

• Molecular mechanisms of myocardial remodeling. The role of aldosterone.

  Journal of molecular and cellular cardiology 20021201

• NF-kappaB activation is essential for angiotensin II-dependent proliferation and migration of vascular smooth muscle cells.

  Journal of molecular and cellular cardiology 20021201

• Vascular effects of COX inhibition and AT1 receptor blockade in transgenic rats harboring mouse renin-2 gene.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20021201

• Emerging role of angiotensin II type 1 receptor blockers for the treatment of endothelial dysfunction and vascular inflammation.

  The Canadian journal of cardiology 20021201

• Progression of renal failure delayed by use of losartan in a case of IgA nephropathy.

  Internal medicine (Tokyo, Japan) 20021201

• Effects of angiotensin II receptor antagonists on [(123)I]metaiodobenzylguanidine myocardial imaging findings and neurohumoral factors in chronic heart failure.

  Heart and vessels 20021201

• Angiotensin II induces a rapid and transient increase of reactive oxygen species.

  Antioxidants & redox signaling 20021201

• ACE-I and ARBs in early diabetic nephropathy.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20021201

• [Suboptimal results of Optimaal: treatment with ACE inhibitors remains the preferred therapy in patients with left ventricular dysfunction after acute myocardial infarct]].

  Herz 20021201

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20021201

• Effect of losartan on the Na+/Ca2+ exchanger in left ventricle of the insulin resistant and hypertensive hHTg rat.

  General physiology and biophysics 20021201

• Comparison of the effects of losartan, enalapril and their combination in the prevention of left ventricular remodeling after acute myocardial infarction in the rat.

  Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20021201

• Superoxide mediates the actions of angiotensin II in the central nervous system.

  Circulation research 20021129

• [Lowering blood pressure with sartans. Are there differences?].

  MMW Fortschritte der Medizin 20021121

• Crumbling of left ventricular hypertrophy as a surrogate end point (the Losartan for Intervention for Endpoint Reduction in Hypertension [LIFE] Study).

  The American journal of cardiology 20021115

• [Is one antihypertensive agent as good as another?].

  MMW Fortschritte der Medizin 20021107

• Contribution of angiotensin II internalization to intrarenal angiotensin II levels in rats.

  American journal of physiology. Renal physiology 20021101

• Differential evolution of blood pressure and renal lesions after RAS blockade in Lyon hypertensive rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20021101

• Are all antihypertensive drug classes equal in reducing left ventricular hypertrophy?

  Current cardiology reports 20021101

• The ERK pathway regulates Na(+)-HCO(3)(-) cotransport activity in adult rat cardiomyocytes.

  American journal of physiology. Heart and circulatory physiology 20021101

• Amlodipine versus Angiotensin-receptor blockers for nonhypertension indications.

  The Annals of pharmacotherapy 20021101

• Antihypertensive treatment in patients with type-2 diabetes mellitus: what guidance from recent controlled randomized trials?

  Journal of hypertension 20021101

• Left but not right cardiac hypertrophy in atrial natriuretic peptide receptor-deficient mice is prevented by angiotensin type 1 receptor antagonist losartan.

  Journal of cardiovascular pharmacology 20021101

• Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7).

  Hypertension (Dallas, Tex. : 1979) 20021101

• Clinical implications of aldosterone blockade.

  American heart journal 20021101

• Angiotensin AT(1)-receptors depolarize neonatal spinal motoneurons and other ventral horn neurons via two different conductances.

  Journal of neurophysiology 20021101

• Intracellular angiotensin II increases the long isoform of PDGF mRNA in rat hepatoma cells.

  Journal of molecular and cellular cardiology 20021101

• Effect of losartan on nocturnal blood pressure in patients with stroke: comparison with angiotensin converting enzyme inhibitor.

  American journal of hypertension 20021101

• Low doses of angiotensin converting enzyme inhibitors and angiotensin type 1 blockers have a synergistic effect but high doses are less than additive.

  American journal of hypertension 20021101

• Renal and cardiovascular protection in type 2 diabetes mellitus: angiotensin II receptor blockers.

  Journal of the American Society of Nephrology : JASN 20021101

• Pharmacologic management of diabetic nephropathy.

  Clinical therapeutics 20021101

• [Changed guidelines of the German High Blood Pressure League. AT(1) blocker in the first league now].

  MMW Fortschritte der Medizin 20021031

• Activation of hypothalamic angiotensin receptors produces pressor responses via cholinergic inputs to the rostral ventrolateral medulla in normotensive and hypertensive rats.

  Brain research 20021025

• Effects of aging and AT-1 receptor blockade on NO synthase expression and renal function in SHR.

  Biochimica et biophysica acta 20021021

• [Left ventricular hypertrophy. Recent aspects of diagnosis and therapy].

  MMW Fortschritte der Medizin 20021017

• Antagonist interaction with endogenous AT(1) receptors in human cell lines.

  Biochemical pharmacology 20021015

• Development and validation of a stability-indicating HPLC method for the simultaneous determination of losartan potassium, hydrochlorothiazide, and their degradation products.

  Journal of pharmaceutical and biomedical analysis 20021015

• Immune thrombocytopenia after losartan therapy.

  Annals of internal medicine 20021015

• Was the LIFE trial independent?

  Lancet (London, England) 20021012

• Was the LIFE trial independent?

  Lancet (London, England) 20021012

• Hypertension-linked decrease in the expression of brain gamma-adducin.

  Circulation research 20021004

• The effects of losartan and fosinopril in hypertensive type 2 diabetic patients.

  Diabetes research and clinical practice 20021001

• Opportunities for cardiovascular risk reduction with angiotensin II receptor blockers.

  Current hypertension reports 20021001

• Inhibitory effect of losartan, an AT1 angiotensin II receptor antagonist, on increased leucocyte entrapment in retinal microcirculation of diabetic rats.

  The British journal of ophthalmology 20021001

• Nonpeptide antagonists of AT1 receptor for angiotensin II delay the onset of acute respiratory distress syndrome.

  The Journal of pharmacology and experimental therapeutics 20021001

• Cross-talk between AT(1) and AT(2) angiotensin receptors in rat anococcygeus smooth muscle.

  The Journal of pharmacology and experimental therapeutics 20021001

• Hepatocyte growth factor gene therapy and angiotensin II blockade synergistically attenuate renal interstitial fibrosis in mice.

  Journal of the American Society of Nephrology : JASN 20021001

• Effect of angiotensin receptor antagonist on liver fibrosis in early stages of chronic hepatitis C.

  Hepatology (Baltimore, Md.) 20021001

• Effects of angiotensin II subtype 1 receptor blockade by losartan on tubulointerstitial lesions caused by hyperoxaluria.

  The Journal of urology 20021001

• Iron overload augments angiotensin II-induced cardiac fibrosis and promotes neointima formation.

  Circulation 20021001

• Regional variation in electrically-evoked contractions of rabbit isolated pulmonary artery.

  British journal of pharmacology 20021001

• The CYP2C9 genotype predicts the blood pressure response to irbesartan: results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA) trial.

  Journal of hypertension 20021001

• Preventing increases in early-morning blood pressure, heart rate, and the rate-pressure product with controlled onset extended release verapamil at bedtime versus enalapril, losartan, and placebo on arising.

  American heart journal 20021001

• Effect of angiotensin II on ion transport across human Fallopian tube epithelial cells in vitro.

  Reproduction (Cambridge, England) 20021001

• Angiotensin II AT1 receptor antagonists inhibit platelet adhesion and aggregation by nitric oxide release.

  Hypertension (Dallas, Tex. : 1979) 20021001

• Angiotensin II's antiproliferative effects mediated through AT2-receptors depend on down-regulation of SM-20.

  Laboratory investigation; a journal of technical methods and pathology 20021001

• Different contribution of apoptosis to the antiproliferative effects of L-arginine, enalapril and losartan on neointimal growth inhibition after balloon arterial injury.

  Circulation journal : official journal of the Japanese Circulation Society 20021001

• Beyond blood pressure: the endothelium and atherosclerosis progression.

  American journal of hypertension 20021001

• The role of angiotensin II receptor blockers in preventing the progression of renal disease in patients with type 2 diabetes.

  American journal of hypertension 20021001

• [Tendency and prospect of the development of new ARBs].

  Nihon rinsho. Japanese journal of clinical medicine 20021001

• [Angiotensin II type 1 antagonist suppress left ventricular hypertrophy and myocardial fibrosis in patient with end stage renal disease (ESRD)].

  Nihon rinsho. Japanese journal of clinical medicine 20021001

• [Acute myocardial infarction].

  Nihon rinsho. Japanese journal of clinical medicine 20021001

• [Large scale clinical trials in prevention of end-stage renal disease due to type 2 diabetes with angiotensin receptor antagonists].

  Nihon rinsho. Japanese journal of clinical medicine 20021001

• Losartan reduced stroke and new onset diabetes more than atenolol in essential hypertension with signs of left ventricular hypertrophy.

  Evidence-based nursing 20021001

• Effect of the angiotensin II receptor antagonist losartan on uric acid and oxypurine metabolism in healthy subjects.

  Internal medicine (Tokyo, Japan) 20021001

• Assessment of drug effects on blood pressure and pulse pressure using clinic, home and ambulatory measurements.

  Journal of human hypertension 20021001

• [Evidence for the benefits of ACE inhibitors and AII antagonists in slowing progressive renal failure in diabetes].

  Nihon rinsho. Japanese journal of clinical medicine 20021001

• [Effect of angiotensin II receptor antagonist (losartan) on renal function, serum potassium and blood pressure in patients with advanced renal failure: differences between patients with a serum creatinine (SCr) level higher than 3 mg/dl and those with a lower SCr level].

  Nihon Jinzo Gakkai shi 20021001

• [Regulation of alpha(1) type I collagen promoter by cytokines and losartan].

  Zhonghua nei ke za zhi 20021001

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20021001

• The effects of losartan and enalapril therapies on the levels of nitric oxide, malondialdehyde, and glutathione in patients with essential hypertension.

  The Japanese journal of physiology 20021001

• An open comparative clinical trial to assess the efficacy and safety of losartan versus enalapril in mild to moderate hypertension.

  The Journal of the Association of Physicians of India 20021001

• [Antihypertensive treatment in patients with diabetes mellitus].

  Polskie Archiwum Medycyny Wewnetrznej 20021001

• Cost allocation in antihypertensive drug therapies.

  Expert review of pharmacoeconomics & outcomes research 20021001

• Effects of losartan on cardiovascular morbidity and mortality in patients with isolated systolic hypertension and left ventricular hypertrophy: a Losartan Intervention for Endpoint Reduction (LIFE) substudy.

  JAMA 20020925

• [Isolated systolic hypertension. 'AT1 blocker preferred over beta-blocker'].

  MMW Fortschritte der Medizin 20020919

• [German Hypertension League on the LIFE Study. New evaluation of AT1 receptor antagonists].

  MMW Fortschritte der Medizin 20020919

• [What are the consequences of the LIFE Study for general practice].

  MMW Fortschritte der Medizin 20020919

• Gbeta gamma -independent constitutive association of Galpha s with SHP-1 and angiotensin II receptor AT2 is essential in AT2-mediated ITIM-independent activation of SHP-1.

  Proceedings of the National Academy of Sciences of the United States of America 20020917

• Design, synthesis and biological evaluation of cyclic angiotensin II analogues with 3,5 side-chain bridges. Role of C-terminal aromatic residue and ring cluster for activity and implications in the drug design of AT1 non-peptide antagonists.

  Bioorganic & medicinal chemistry letters 20020916

• Angiotensin II influences the hyperpolarization-activated current Ih in neurones of the rat paraventricular nucleus.

  Neuroscience letters 20020913

• Effects of losartan and captopril on mortality and morbidity in high-risk patients after acute myocardial infarction: the OPTIMAAL randomised trial. Optimal Trial in Myocardial Infarction with Angiotensin II Antagonist Losartan.

  Lancet (London, England) 20020907

• Glia- and neuron-specific expression of the renin-angiotensin system in brain alters blood pressure, water intake, and salt preference.

  The Journal of biological chemistry 20020906

• Comparison of UV- and second derivative-spectrophotometric and LC methods for the determination of valsartan in pharmaceutical formulation.

  Journal of pharmaceutical and biomedical analysis 20020905

• Association of renal injury with nitric oxide deficiency in aged SHR: prevention by hypertension control with AT1 blockade.

  Kidney international 20020901

• Dual renin-angiotensin system blockade at optimal doses for proteinuria.

  Kidney international 20020901

• Part 1. Uric acid and losartan.

  Current opinion in nephrology and hypertension 20020901

• Sympatholytic properties of several AT1-receptor antagonists in the isolated rabbit thoracic aorta.

  Journal of hypertension 20020901

• Effects of losartan and atenolol on left ventricular mass and neurohormonal profile in patients with essential hypertension and left ventricular hypertrophy.

  Journal of hypertension 20020901

• Risk of new-onset diabetes in the Losartan Intervention For Endpoint reduction in hypertension study.

  Journal of hypertension 20020901

• Angiotensin II type 1 receptor blockade restores nitric oxide-dependent renal vascular responses in renovascular hypertension.

  Journal of cardiovascular pharmacology 20020901

• Effects of chronic subdepressor dose of angiotensin II type 1 receptor antagonist on endothelium-dependent vasodilation in patients with congestive heart failure.

  Journal of cardiovascular pharmacology 20020901

• N(G)-nitro-L-arginine methyl ester-induced hypertension and natriuretic peptide gene expression: inhibition by angiotensin II type 1 receptor antagonism.

  Journal of cardiovascular pharmacology 20020901

• Sartans, angiotensin II receptor antagonists, can induce psoriasis.

  The British journal of dermatology 20020901

• Prevention of cardiovascular morbidity with angiotension receptor blockade: life after LIFE.

  Diabetic medicine : a journal of the British Diabetic Association 20020901

• No morbidity-mortality. Commentary.

  Diabetic medicine : a journal of the British Diabetic Association 20020901

• Pharmacokinetic evaluation of the possible interaction between selected concomitant medications and orlistat at steady state in healthy subjects.

  Journal of clinical pharmacology 20020901

• Interaction between paraventricular nucleus and septal area in the control of physiological responses induced by angiotensin II.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020901

• Angiotensin and baroreflex control of the circulation.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020901

• Dissociation between the circulating renin-angiotensin system and angiotensin II receptors in central losartan-induced hypertension.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020901

• Angiotensin II receptor blocker-associated angioedema: on the heels of ACE inhibitor angioedema.

  Pharmacotherapy 20020901

• Is cardiovascular remodeling in patients with essential hypertension related to more than high blood pressure? A LIFE substudy. Losartan Intervention For Endpoint-Reduction in Hypertension.

  American heart journal 20020901

• Evaluation of potential losartan-phenytoin drug interactions in healthy volunteers.

  Clinical pharmacology and therapeutics 20020901

• Losartan and lercanidipine attenuate low-density lipoprotein oxidation in patients with hypertension and type 2 diabetes mellitus: a randomized, prospective crossover study.

  Clinical pharmacology and therapeutics 20020901

• [Beyond blood pressure reduction in the treatment of arterial hypertension. Clinical implications of the LIFE study].

  Revista espanola de cardiologia 20020901

• Angiotensin receptor antagonist losartan improves endothelial function of epicardial coronary arteries in patients with essential hypertension.

  Clinical cardiology 20020901

• [What is a good marker for better antihypertensive therapy in diabetic patients when coexisting with hypertension].

  Nihon rinsho. Japanese journal of clinical medicine 20020901

• Apoptosis, myocardial fibrosis and angiotensin II in the left ventricle of hypertensive rats treated with fosinopril or losartan.

  Chinese medical journal 20020901

• Gateways to Clinical Trials.

  Methods and findings in experimental and clinical pharmacology 20020901

• Contrasting effects of angiotensin type 1 and 2 receptors on nitric oxide release under pressure.

  Hypertension research : official journal of the Japanese Society of Hypertension 20020901

• Regression of left ventricular hypertrophy: hoping for a longer life.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20020901

• Vitamins, antioxidants and endothelial function in coronary artery disease.

  Cardiovascular drugs and therapy 20020901

• Beta-blockers and diabetes: the bad guys come good.

  Cardiovascular drugs and therapy 20020901

• Effects of AT1 and AT2 receptor blockade on angiotensin II induced apoptosis of human renal proximal tubular epithelial cells.

  Wiener klinische Wochenschrift 20020830

• Augmentation of myocardial blood flow in hypertensive heart disease by angiotensin antagonists: a comparison of lisinopril and losartan.

  Journal of the American College of Cardiology 20020821

• Influence of ANG II on cytoplasmic sodium in cultured rabbit nonpigmented ciliary epithelium.

  American journal of physiology. Cell physiology 20020801

• Angiotensin II regulation of vascular endothelial growth factor and receptors Flt-1 and KDR/Flk-1 in cyclosporine nephrotoxicity.

  Kidney international 20020801

• Determination of losartan and hydrochlorothiazide in tablets by CE and CEC.

  Journal of pharmaceutical and biomedical analysis 20020801

• Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol.

  Current hypertension reports 20020801

• Effects of combined treatment with enalapril and losartan on myocardial function in heart failure.

  Heart (British Cardiac Society) 20020801

• Lipopolysaccharide induces apoptosis in adult rat ventricular myocytes via cardiac AT(1) receptors.

  American journal of physiology. Heart and circulatory physiology 20020801

• Angiotensin II stimulates contraction and growth of testicular peritubular myoid cells in vitro.

  Endocrinology 20020801

• Ischemia promotes renin activation and angiotensin formation in sympathetic nerve terminals isolated from the human heart: contribution to carrier-mediated norepinephrine release.

  The Journal of pharmacology and experimental therapeutics 20020801

• Nitroglycerin tolerance: different mechanisms in vascular segments with or without intact endothelial function.

  Journal of cardiovascular pharmacology 20020801

• AT(1)-receptor blockers: differences that matter.

  Journal of human hypertension 20020801

• Combination therapy with AT(1)-receptor blockers.

  Journal of human hypertension 20020801

• Optimal dose of losartan for renoprotection in diabetic nephropathy.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020801

• Effects of enalapril and losartan on circulating adhesion molecules and monocyte chemotactic protein-1.

  Clinical science (London, England : 1979) 20020801

• A population-based European cohort study of persistence in newly diagnosed hypertensive patients.

  Journal of human hypertension 20020801

• A blood pressure independent association between glomerular albumin leakage and electrocardiographic left ventricular hypertrophy. The LIFE Study. Losartan Intervention For Endpoint reduction.

  Journal of human hypertension 20020801

• A randomised, double-blind, double-dummy comparison of the efficacy and tolerability of lercanidipine tablets and losartan tablets in patients with mild to moderate essential hypertension.

  Journal of human hypertension 20020801

• Efficacy of eplerenone added to renin-angiotensin blockade in hypertensive patients.

  Hypertension (Dallas, Tex. : 1979) 20020801

• Mineralocorticoid and angiotensin receptor antagonism during hyperaldosteronemia.

  Hypertension (Dallas, Tex. : 1979) 20020801

• Ethnic differences in electrocardiographic criteria for left ventricular hypertrophy: the LIFE study. Losartan Intervention For Endpoint.

  American journal of hypertension 20020801

• Influence of antihypertensive drugs on renal microcirculation and renal hemodynamics in cyclosporine A-treated rats.

  Transplantation proceedings 20020801

• Angiotensin II type 1 receptor blockade after cardiac transplantation reduced the incidence and severity of transplant vasculopathy in an animal-based study.

  Transplantation proceedings 20020801

• Activation of angiotensin II type I receptor promotes protein kinase C translocation and cell proliferation in human cultured breast epithelial cells.

  The Journal of endocrinology 20020801

• Effect of experimental renal failure on the pharmacokinetics of losartan in rats.

  Biological & pharmaceutical bulletin 20020801

• Role of endothelin receptors in the hypertensive state of kinin B(2) knockout mice subjected to a high-salt diet.

  Clinical science (London, England : 1979) 20020801

• [Addition of an angiotensin II receptor blocker to maximal dose of ACE inhibitors in heart failure].

  Revista espanola de cardiologia 20020801

• [Acute myocardial failure in a young man: Q-fever myocarditis].

  Revista espanola de cardiologia 20020801

• Intra-individual variability in urinary losartan oxidation ratio, an in vivo marker of CYP2C9 activity.

  British journal of clinical pharmacology 20020801

• Antihypertensive and metabolic effects of whole Maitake mushroom powder and its fractions in two rat strains.

  Molecular and cellular biochemistry 20020801

• What is the meaning of LIFE? Implications of the Losartan Intervention for Endpoint reduction in hypertension trial for heart failure physicians.

  Journal of cardiac failure 20020801

• Key role of P38 mitogen-activated protein kinase and the lipoxygenase pathway in angiotensin II actions in H295R adrenocortical cells.

  Endocrine 20020801

• Binding of KRH-594, an antagonist of the angiotensin II type 1 receptor, to cloned human and rat angiotensin II receptors.

  Fundamental & clinical pharmacology 20020801

• [Preventing stroke. Which antihypertensive drugs can do it better?].

  MMW Fortschritte der Medizin 20020726

• Effects of losartan on the blood-brain barrier permeability in long-term nitric oxide blockade-induced hypertensive rats.

  Life sciences 20020712

• Angiotensin II and cAMP regulate AT(1)-mRNA expression in rat cardiomyocytes by transcriptional mechanism.

  European journal of pharmacology 20020712

• Change in systolic left ventricular performance after 3 years of antihypertensive treatment: the Losartan Intervention for Endpoint (LIFE) Study.

  Circulation 20020709

• Who is fooling us?

  Lancet (London, England) 20020706

• Angiotensin II inhibits human trophoblast invasion through AT1 receptor activation.

  The Journal of biological chemistry 20020705

• Angiotensin actions on the isolated rat uterus during the estrous cycle: influence of resting membrane potential and uterine morphology.

  Pharmacology 20020701

• Altered mitogen-activated protein kinase activation in vascular smooth muscle cells from spontaneously hypertensive rats.

  Clinical and experimental pharmacology & physiology 20020701

• Angiotensin II induces apoptosis in rat glomerular epithelial cells.

  American journal of physiology. Renal physiology 20020701

• The renin-angiotensin-aldosterone system excites hypothalamic paraventricular nucleus neurons in heart failure.

  American journal of physiology. Heart and circulatory physiology 20020701

• Renoprotective effects of losartan in diabetic nephropathy: interaction with ACE insertion/deletion genotype?

  Kidney international 20020701

• Effect of losartan on plasma C-reactive protein in type 2 diabetic patients with microabluminuria.

  Diabetes care 20020701

• Angiotensin II stimulates calcineurin activity in proximal tubule epithelia through AT-1 receptor-mediated tyrosine phosphorylation of the PLC-gamma1 isoform.

  Journal of the American Society of Nephrology : JASN 20020701

• Losartan potassium, a non-peptide agent for the treatment of arterial hypertension.

  Acta crystallographica. Section C, Crystal structure communications 20020701

• Central AT1 receptors are involved in the enhanced cardiac sympathetic afferent reflex in rats with chronic heart failure.

  Basic research in cardiology 20020701

• Losartan attenuates renal vasoconstriction in response to acute unilateral ureteral occlusion in pigs.

  Urological research 20020701

• Efficacy and safety of losartan in patients with proteinuria.

  Nephron 20020701

• Recent landmark clinical trials: how do they modify the therapeutic paradigm?

  American journal of hypertension 20020701

• AT1 angiotensin II receptor mediates intracellular calcium mobilization in normal and cancerous breast cells in primary culture.

  Cell calcium 20020701

• Angiotensin II-dependent structural changes of preglomerular resistance may affect long-term control of blood pressure by resetting the renal 'baroreceptor'.

  Journal of hypertension 20020701

• Brief losartan treatment in young spontaneously hypertensive rats abates long-term blood pressure elevation by effects on renal vascular structure.

  Journal of hypertension 20020701

• Progressive hypertrophy regression with sustained pressure reduction in hypertension: the Losartan Intervention For Endpoint Reduction study.

  Journal of hypertension 20020701

• 11beta-hydroxysteroid dehydrogenase activity in proteinuric patients and the effect of angiotensin-II receptor blockade.

  European journal of clinical investigation 20020701

• Losartan more effective than atenolol in hypertension with left ventricular hypertrophy.

  The Journal of family practice 20020701

• The role of angiotensin II antagonism in type 2 diabetes mellitus: a review of renoprotection studies.

  Clinical therapeutics 20020701

• A multicenter, randomized, double-blind, placebo-controlled, 8-week trial of the efficacy and tolerability of once-daily losartan 100 mg/hydrochlorothiazide 25 mg and losartan 50 mg/hydrochlorothiazide 12.5 mg in the treatment of moderate-to-severe essential hypertension.

  Clinical therapeutics 20020701

• Comparison of the effects of losartan and atenolol on common carotid artery intima-media thickness in patients with hypertension: results of a 2-year, double-blind, randomized, controlled study.

  Clinical therapeutics 20020701

• The effect of losartan intervention on the regulation of pulmonary arterial collagen expression by protein kinase C in chronic hypoxic rat models.

  Zhonghua nei ke za zhi 20020701

• [Prevention of type II diabetes by inhibiting the renin-angiotensin system].

  Revue medicale de Liege 20020701

• Functional antagonism of different angiotensin II type I receptor blockers in human arteries.

  Cardiovascular drugs and therapy 20020701

• Effect of dietary sodium intake on central angiotensinergic pathways.

  Autonomic neuroscience : basic & clinical 20020628

• Losartan for cardiovascular disease in patients with and without diabetes in the LIFE study.

  Lancet (London, England) 20020622

• Losartan for cardiovascular disease in patient's with and without diabetes in the LIFE study.

  Lancet (London, England) 20020622

• Losartan for cardiovascular disease in patient's with and without diabetes in the LIFE study.

  Lancet (London, England) 20020622

• Losartan for cardiovascular disease in patient's with and without diabetes in the LIFE study.

  Lancet (London, England) 20020622

• Losartan for cardiovascular disease in patient's with and without diabetes in the LIFE study.

  Lancet (London, England) 20020622

• Losartan for cardiovascular disease in patient's with and without diabetes in the LIFE study.

  Lancet (London, England) 20020622

• Losartan for cardiovascular disease in patient's with and without diabetes in the LIFE study.

  Lancet (London, England) 20020622

• Losartan for cardiovascular disease in patient's with and without diabetes in the LIFE study.

  Lancet (London, England) 20020622

• Losartan for cardiovascular disease in patient's with and without diabetes in the LIFE study.

  Lancet (London, England) 20020622

• Losartan for cardiovascular disease in patient's with and without diabetes in the LIFE study.

  Lancet (London, England) 20020622

• Effect of exogenous and endogenous angiotensin II on intrarenal distribution of glomerular filtration rate in rats.

  The Journal of physiology 20020615

• [ACE inhibitor or AT1 antagonist. Is there a differential therapy?].

  MMW Fortschritte der Medizin 20020613

• Angiotensin-converting enzyme inhibitors improve coronary flow reserve in dilated cardiomyopathy by a bradykinin-mediated, nitric oxide-dependent mechanism.

  Circulation 20020611

• Angiotensin II stimulates synthesis of vascular smooth muscle cell proteoglycans with enhanced low density lipoprotein binding properties.

  Atherosclerosis 20020601

• Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism.

  American journal of physiology. Renal physiology 20020601

• Angiotensin converting enzyme inhibitors or angiotensin receptor blockers in nephropathy from type 2 diabetes.

  Current hypertension reports 20020601

• Do angiotensin receptor antagonists have benefits beyond blood pressure lowering?

  Current hypertension reports 20020601

• Microinjection of ANG II into paraventricular nucleus enhances cardiac sympathetic afferent reflex in rats.

  American journal of physiology. Heart and circulatory physiology 20020601

• Diminished arteriolar responses in nitrate tolerance involve ROS and angiotensin II.

  American journal of physiology. Heart and circulatory physiology 20020601

• Angiotensin-II receptor antagonist losartan reduces microalbuminuria in hypertensive renal transplant recipients.

  Clinical transplantation 20020601

• Site-directed mutagenesis of the gerbil and human angiotensin II AT(1) receptors identifies amino acid residues attributable to the binding affinity for the nonpeptidic antagonist losartan.

  Molecular pharmacology 20020601

• Angiotensin II and IV stimulate expression and release of plasminogen activator inhibitor-1 in cultured human coronary artery endothelial cells.

  Journal of cardiovascular pharmacology 20020601

• Trough-to-peak ratio, smoothness index, and circadian blood pressure profile after treatment with once-daily fixed combination of losartan 100 and hydrochlorothiazide 25 in essential hypertension.

  Journal of cardiovascular pharmacology 20020601

• Differences in AT2 -receptor stimulation between AT1 -receptor blockers valsartan and losartan quantified by renal interstitial fluid cGMP.

  Journal of hypertension 20020601

• Impact of diastolic Doppler indices on exercise capacity in hypertensive patients with electrocardiographic left ventricular hypertrophy (a LIFE substudy).

  Journal of hypertension 20020601

• Angiotensin II activates nuclear transcription factor-kappaB through AT1 and AT2 receptors.

  Kidney international 20020601

• Potentiation of [Ca2+]i response to angiotensin III by cAMP in cortical thick ascending limb.

  Kidney international 20020601

• The mechanism of improved sodium homeostasis of low-dose losartan in preascitic cirrhosis.

  Hepatology (Baltimore, Md.) 20020601

• Urinary transforming growth factor-beta excretion in patients with hypertension, type 2 diabetes, and elevated albumin excretion rate: effects of angiotensin receptor blockade and sodium restriction.

  Diabetes care 20020601

• The effects of losartan on renal function in the newborn rabbit.

  Pediatric research 20020601

• Efficacy of angiotensin II receptor antagonists in preventing headache: a systematic overview and meta-analysis.

  The American journal of medicine 20020601

• Renin-angiotensin system expression and secretory function in cultured human ciliary body non-pigmented epithelium.

  The British journal of ophthalmology 20020601

• The impact of angiotensin II receptor blockade and the DASH diet on markers of endogenous fibrinolysis.

  Journal of human hypertension 20020601

• Blood pressure, cardiac, and renal responses to salt and deoxycorticosterone acetate in mice: role of Renin genes.

  Journal of the American Society of Nephrology : JASN 20020601

• Tonin expression in the rat brain and tonin-mediated central production of angiotensin II.

  Physiology & behavior 20020601

• Losartan reduces central and peripheral sympathetic nerve activity in a rat model of neurogenic hypertension.

  Hypertension (Dallas, Tex. : 1979) 20020601

• [Treatment of post kidney transplantation erythrocytosis (PTE) with ACE inhibitors].

  Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20020601

• Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity.

  Journal of clinical pharmacy and therapeutics 20020601

• Effects of antihypertensive therapy on cardiac sodium/hydrogen ion exchanger activity and hypertrophy in spontaneously hypertensive rats.

  The Canadian journal of cardiology 20020601

• The effect of losartan potassium on choroidal hemodynamics in healthy subjects.

  Journal of glaucoma 20020601

• The effects of peptide and nonpeptide antagonists of angiotensin II receptors on the level of brain biogenic monoamines in rats with angiotensin II-induced increase of water intake.

  Methods and findings in experimental and clinical pharmacology 20020601

• Restoration of glomerular haemodynamics and renal injury independent of arterial hypertension in rats with subtotal renal ablation.

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20020601

• Differentiation in the effects of the angiotensin II receptor blocker class on autonomic function.

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20020601

• AT1 blockers and uric acid metabolism: are there relevant differences?

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20020601

• Sympatho-inhibitory properties of various AT1 receptor antagonists.

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20020601

• Evolving therapeutic strategies for retarding progression of diabetic nephropathy--an update for 2002.

  Acta diabetologica 20020601

• Combining renin-angiotensin-aldosterone system blockade with diuretic therapy for treatment of hypertension.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20020601

• Losartan-dependent regression of myocardial fibrosis is associated with reduction of left ventricular chamber stiffness in hypertensive patients.

  Circulation 20020528

• [Irbesartan: a new possibility in the treatment of hypertension].

  Orvosi hetilap 20020526

• [Disruption of the D(2) dopamine receptor produces adrenergic and endothelin B receptor-dependent hypertension].

  Zhonghua yi xue za zhi 20020525

• [The LIFE study: extensive marketing in Denmark. Suggestions to conclusions based on the study].

  Lakartidningen 20020516

• [Better prognosis in hypertension and left ventricular hypertrophy. LIFE Study sets new standard].

  MMW Fortschritte der Medizin 20020516

• 125I[Sar(1)Ile(8)] angiotensin II has a different affinity for AT(1) and AT(2) receptor subtypes in ovine tissues.

  Regulatory peptides 20020515

• Contemporary medical options for treating patients with heart failure.

  Circulation 20020514

• Angiotensin II activation of focal adhesion kinase and pp60c-Src in relation to mitogen-activated protein kinases in hepatocytes.

  Biochimica et biophysica acta 20020508

• Two angiotensin AT1 receptor antagonists, irbesartan and losartan, effects in cholesterol-fed rabbits.

  European journal of pharmacology 20020503

• Interaction of angiotensin II and adenosine A1 and A2A receptor ligands on the writhing test in mice.

  Pharmacology, biochemistry, and behavior 20020501

• Effect of AT(1) receptor blockade on cardiac apoptosis in angiotensin II-induced hypertension.

  American journal of physiology. Heart and circulatory physiology 20020501

• Raynaud's phenomenon affecting the tongue of a patient with scleroderma.

  Annals of the rheumatic diseases 20020501

• Angiotensin II directly stimulates ENaC activity in the cortical collecting duct via AT(1) receptors.

  Journal of the American Society of Nephrology : JASN 20020501

• Antihypertensive efficacy of olmesartan compared with other antihypertensive drugs.

  Journal of human hypertension 20020501

• Effects of angiotensin II microinjected into medial amygdala on male sexual behavior in rats.

  Hormones and behavior 20020501

• Inhibition of vascular smooth muscle cell growth by angiotensin type 2 receptor stimulation for in vitro organ culture model.

  Journal of cardiovascular pharmacology 20020501

• Accelerated recovery from irradiation injury by angiotensin peptides.

  Cancer chemotherapy and pharmacology 20020501

• Anaphylactic reaction during haemodialysis on AN69 membrane in a patient receiving angiotensin II receptor antagonist.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020501

• Effect of 1-week losartan administration on bile duct-ligated cirrhotic rats with portal hypertension.

  Journal of hepatology 20020501

• Discussion on randomized comparison of long-term losartan versus propranolol in lowering portal pressure in cirrhosis.

  Gastroenterology 20020501

• Reversible ageusia induced by losartan: a case report.

  European journal of neurology 20020501

• Class benefits of AT(1) antagonists in Type 2 diabetes with nephropathy.

  Expert opinion on pharmacotherapy 20020501

• Postnatal hypoxemia increases angiotensin II sensitivity and up-regulates AT1a angiotensin receptors in rat carotid body chemoreceptors.

  The Journal of endocrinology 20020501

• Angiotensin II stimulation of Na+/K+ATPase activity and cell growth by calcium-independent pathway in MCF-7 breast cancer cells.

  The Journal of endocrinology 20020501

• Vasodilatory capacity and vascular structure in long-standing hypertension: a LIFE substudy. Losartan Intervention For Endpoint-Reduction in Hypertension.

  American journal of hypertension 20020501

• Effects of long-term enalapril and losartan therapy of heart failure on cardiovascular aldosterone.

  Journal of endocrinological investigation 20020501

• ARB superior to beta blocker in preventing adverse outcomes in older, high-risk hypertensive patients.

  Geriatrics 20020501

• Angiotensin blockade in type 2 diabetes: what the new evidence tells us about renal and cardiac complications.

  The Canadian journal of cardiology 20020501

• Vascular changes in hypertension in response to drug treatment: Effects of angiotensin receptor blockers.

  The Canadian journal of cardiology 20020501

• [LIFE-study: losartan reduces cardiovascular risk factors more than atenolol].

  Medizinische Monatsschrift fur Pharmazeuten 20020501

• Systemic site of action for pressor effect of angiotensin II injected into the fourth cerebral ventricle of rats?

  Canadian journal of physiology and pharmacology 20020501

• [Comparative effects of losartan and amlodipine on activities of sympathetic nerve, renin-angiotensin-aldosterone system and brain natriuretic peptide in the elderly hypertensive patients].

  Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20020501

• Losartan and the meaning of LIFE.

  Journal of human hypertension 20020501

• [The RENAAL Study. Effect of losartan on diabetic nephropathy].

  Der Internist 20020501

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20020501

• [Losartan in the rat model of bleomycin-induced pulmonary fibrosis and its impact on the expression of monocyte chemoattractant protein-1 and basic fibroblast growth factor].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20020501

• Cyclic AMP-dependent protein kinase-independent angiotensin II-induced inhibition of calcium current in hamster submandibular ganglion neurons.

  The Bulletin of Tokyo Dental College 20020501

• [Angiotensin receptor antagonists and ACE inhibitors in heart failure: alternative or combined therapies?].

  Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20020501

• [Effect of losartan and amilodipine on the platelet activation and renal function in patients with mild and moderate hypertension].

  Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20020428

• [Marketing of researchers--lack of judgment or a new trend?].

  Lakartidningen 20020425

• [Marketing of the LIFE trial anticipates evaluation of the drug].

  Lakartidningen 20020425

• Losartan potassium (Cozaar).

  Circulation 20020423

• Novel AT(1) receptor-independent functions of losartan.

  Circulation research 20020419

• Angiotensin II receptor-independent antiinflammatory and antiaggregatory properties of losartan: role of the active metabolite EXP3179.

  Circulation research 20020419

• [Results from the LIFE study: promising effects of new hypertensive agents].

  Lakartidningen 20020418

• AT(1) receptor blockade with losartan during gestation in Wistar rats leads to an increase in thirst and sodium appetite in their adult female offspring.

  Regulatory peptides 20020415

• [Type 2 diabetes and nephropathy--new studies, new treatment strategies?].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20020410

• [Hypertension plus left ventricular hypertrophy. Prognosis can now be significantly improved].

  MMW Fortschritte der Medizin 20020404

• AT(2) but not AT(1) receptor antagonism abolishes angiotensin II increase of the acquisition of conditioned avoidance responses in rats.

  Behavioural brain research 20020401

• Structure elucidation and conformational properties of eprosartan, a non peptide angiotensin II AT1 antagonist.

  Journal of pharmaceutical and biomedical analysis 20020401

• Angiotensin II AT(2) receptor inhibits smooth muscle cell migration via fibronectin cell production and binding.

  American journal of physiology. Cell physiology 20020401

• Angiotensin receptor subtype AT(1) mediates alveolar epithelial cell apoptosis in response to ANG II.

  American journal of physiology. Lung cellular and molecular physiology 20020401

• Angiotensin II stimulates cyclooxygenase-2 mRNA expression in renal tissue from rats with kidney failure.

  American journal of physiology. Renal physiology 20020401

• Effects of losartan and benazepril on abnormal circadian blood pressure rhythm and target organ damage in SHRSP.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20020401

• AT(1) and AT(2) receptor expression and blockade after acute ischemia-reperfusion in isolated working rat hearts.

  American journal of physiology. Heart and circulatory physiology 20020401

• Influence of estrogen and/or progesterone on isolated ovariectomized rat uterus. Responsiveness to Ang II.

  Pharmacology 20020401

• Efficacy of angiotensin II type 1 receptor blockade on reperfusion-induced arrhythmias and mortality early after myocardial infarction is increased in transgenic rats with cardiac angiotensin II type 1 overexpression.

  Journal of cardiovascular pharmacology 20020401

• Functional cross-talk between angiotensin II and epidermal growth factor receptors in NIH3T3 fibroblasts.

  Journal of hypertension 20020401

• Losartan titration versus diuretic combination in type 2 diabetic patients.

  Journal of hypertension 20020401

• A low-sodium diet potentiates the effects of losartan in type 2 diabetes.

  Diabetes care 20020401

• Short-term effects of angiotensin II receptor blockade in patients with primary glomerulonephritis: pilot study.

  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20020401

• Additive antiproteinuric effect of ACE inhibitor and losartan in IgA nephropathy.

  Pediatric nephrology (Berlin, Germany) 20020401

• Effects of high glucose on interleukin-6 production in human mesangial cells.

  Journal of Korean medical science 20020401

• Losartan and perindopril effects on plasma plasminogen activator inhibitor-1 and fibrinogen in hypertensive type 2 diabetic patients.

  American journal of hypertension 20020401

• Effects of the angiotensin receptor antagonist losartan on the response of the left main coronary artery to cold pressor test in patients with essential hypertension as assessed by echocardiography.

  The Canadian journal of cardiology 20020401

• Comment--Val-HeFT and angiotensin-receptor blockers in perspective: A tale of the blind man and the elephant.

  Journal of cardiac failure 20020401

• Effects of captopril and losartan on myocardial ischemia-reperfusion induced arrhythmias and necrosis in rats.

  Pharmacological research 20020401

• [Clinical study of the month. The LIFE study: cardiovascular protection of hypertensive patients by losartan].

  Revue medicale de Liege 20020401

• The effect of losartan on calcium uptake by bovine aortic media in vitro.

  Methods and findings in experimental and clinical pharmacology 20020401

• Angiotensin protects cortical neurons from hypoxic-induced apoptosis via the angiotensin type 2 receptor.

  Brain research. Molecular brain research 20020328

• Angiotensin blockade for hypertension: a promise fulfilled.

  Lancet (London, England) 20020323

• Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol.

  Lancet (London, England) 20020323

• Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol.

  Lancet (London, England) 20020323

• Brain-selective overexpression of angiotensin (AT1) receptors causes enhanced cardiovascular sensitivity in transgenic mice.

  Circulation research 20020322

• Comparison of angiotensin II (Ang II) effects in the internal anal sphincter (IAS) and lower esophageal sphincter smooth muscles.

  Life sciences 20020322

• Effects of cariporide and losartan on hypertrophy, calcium transients, contractility, and gene expression in congestive heart failure.

  Circulation 20020319

• Fast screening method for the determination of angiotensin II receptor antagonists in human plasma by high-performance liquid chromatography with fluorimetric detection.

  Journal of chromatography. A 20020308

• Change in diastolic left ventricular filling after one year of antihypertensive treatment: The Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) Study.

  Circulation 20020305

• Enhanced ammonia secretion by proximal tubules from mice receiving NH(4)Cl: role of angiotensin II.

  American journal of physiology. Renal physiology 20020301

• A rapid colorimetric method for the determination of Losartan potassium in bulk and in synthetic mixture for solid dosage form.

  Journal of pharmaceutical and biomedical analysis 20020301

• Animal model for angiotensin II effects in the internal anal sphincter smooth muscle: mechanism of action.

  American journal of physiology. Gastrointestinal and liver physiology 20020301

• Angiotensin II type 1 receptor blockade ameliorates tubulointerstitial injury induced by chronic potassium deficiency.

  Kidney international 20020301

• Modulation of matrix metalloproteinase-1, its tissue inhibitor, and nuclear factor-kappa B by losartan in hypercholesterolemic rabbits.

  Journal of cardiovascular pharmacology 20020301

• Effect of losartan in aging-related endothelial impairment.

  The American journal of cardiology 20020301

• Angiotensin II type 1 receptor antagonist, losartan, causes regression of left ventricular hypertrophy in end-stage renal disease.

  Nephron 20020301

• Losartan treatment and left ventricular filling during volume loading in patients with dilated cardiomyopathy.

  American heart journal 20020301

• Altered balance of main vasopressor and vasodepressor systems in rats with genetic hypertension and hypertriglyceridaemia.

  Clinical science (London, England : 1979) 20020301

• Changes in pain perception during treatment with angiotensin converting enzyme-inhibitors and angiotensin II type 1 receptor blockade.

  Journal of hypertension 20020301

• Add-on angiotensin II receptor blockade lowers urinary transforming growth factor-beta levels.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20020301

• Effects of losartan or enalapril on hemoglobin, circulating erythropoietin, and insulin-like growth factor-1 in patients with and without posttransplant erythrocytosis.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20020301

• Correlates of left atrial size in hypertensive patients with left ventricular hypertrophy: the Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) Study.

  Hypertension (Dallas, Tex. : 1979) 20020301

• Dysregulation of angiotensin II synthesis is associated with salt sensitivity in the spontaneous hypertensive rat.

  Acta physiologica Scandinavica 20020301

• [The ACE inhibitor, captopril, in the light of new clinical studies].

  Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20020301

• [Efficacy and safety of combination therapy with losartan and hydrochlorothiazide in elderly hypertension].

  Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20020301

• [Angiotensin II receptor antagonists and portal hypertension].

  Gastroenterologie clinique et biologique 20020301

• Interaction of ACE inhibitors and AT(1)-receptor blockers on maximum blood pressure response in spontaneous hypertensive rats.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20020301

• The renin-angiotensin system does not contribute to the endothelial dysfunction and increased infarct size in rats exposed to second hand smoke.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20020301

• Angiotensin II supports sympathetically mediated vasopressor response to footshock-stress.

  Journal of human hypertension 20020301

• Angiotensin II receptor antagonists role in arterial hypertension.

  Journal of human hypertension 20020301

• Combined effect of ACE inhibitor and exercise training on insulin resistance in type 2 diabetic rats.

  Life sciences 20020301

• Efficacy and safety of losartan-amplodipine combination--an Indian postmarketing surveillance experience.

  Journal of the Indian Medical Association 20020301

• Angiotensin-receptor blockers, type 2 diabetes, and renoprotection.

  The New England journal of medicine 20020227

• Angiotensin-receptor blockers, type 2 diabetes, and renoprotection.

  The New England journal of medicine 20020227

• Constitutive internalization of constitutively active agiotensin II AT(1A) receptor mutants is blocked by inverse agonists.

  The Journal of biological chemistry 20020222

• Effects of angiotensin blockade in the rostral ventrolateral medulla on maintenance of hypertension induced by chronic L-NAME treatment.

  Brain research 20020215

• Correlates of pulse pressure reduction during antihypertensive treatment (losartan or atenolol) in hypertensive patients with electrocardiographic left ventricular hypertrophy (the LIFE study).

  The American journal of cardiology 20020215

• Interaction of digoxin with antihypertensive drugs via MDR1.

  Life sciences 20020215

• Calcineurin inhibition attenuates mineralocorticoid-induced cardiac hypertrophy.

  Circulation 20020212

• Angiotensin II reduces macrophage cholesterol efflux: a role for the AT-1 receptor but not for the ABC1 transporter.

  Biochemical and biophysical research communications 20020208

• Angiotensin II stimulates migration of retinal microvascular pericytes: involvement of TGF-beta and PDGF-BB.

  American journal of physiology. Heart and circulatory physiology 20020201

• The mechanism of angiotensin II binding downregulation by high glucose in primary renal proximal tubule cells.

  American journal of physiology. Renal physiology 20020201

• Losartan treatment normalizes renal sodium and water handling in rats with mild congestive heart failure.

  American journal of physiology. Renal physiology 20020201

• Angiotensin II regulates oxygen consumption.

  American journal of physiology. Regulatory, integrative and comparative physiology 20020201

• Variation in the renin angiotensin system throughout the normal menstrual cycle.

  Journal of the American Society of Nephrology : JASN 20020201

• Involvement of cysteinyl leukotrienes in angiotensin II-induced contraction in isolated aortas from transgenic (mRen-2)27 rats.

  Journal of hypertension 20020201

• Mechanisms involved in the water intake-related pressor response in the rat.

  Journal of hypertension 20020201

• Comparative effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricemia and gout.

  Journal of hypertension 20020201

• Identification of a zinc finger homoeodomain enhancer protein after AT(2) receptor stimulation by differential mRNA display.

  Arteriosclerosis, thrombosis, and vascular biology 20020201

• Urine albumin/creatinine ratio and echocardiographic left ventricular structure and function in hypertensive patients with electrocardiographic left ventricular hypertrophy: the LIFE study. Losartan Intervention for Endpoint Reduction.

  American heart journal 20020201

• Effects of antihypertensive therapy on intrarenal angiotensin and bradykinin levels in experimental renal insufficiency.

  Kidney international 20020201

• Comparative effects of chronic ACE inhibition and AT1 receptor blocked losartan on cardiac hypertrophy and renal function in hypertensive patients.

  Journal of human hypertension 20020201

• Enhancement of phosphatidylcholine biosynthesis by angiotensin-(1-7) in the rat renal cortex.

  Biochemical pharmacology 20020201

• Influence of losartan and enalapril on urinary excretion of 8-isoprostane in experimental nephrotic syndrome.

  Medical science monitor : international medical journal of experimental and clinical research 20020201

• In vivo evidence for antioxidant potential of estrogen in microvessels of female spontaneously hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 20020201

• Pressure promotes angiotensin II--mediated migration of human coronary smooth muscle cells through increase in oxidative stress.

  Hypertension (Dallas, Tex. : 1979) 20020201

• Downregulation of neuronal nitric oxide synthase and interleukin-1beta mediates angiotensin II-dependent stimulation of sympathetic nerve activity.

  Hypertension (Dallas, Tex. : 1979) 20020201

• Studies on the angiotensin-converting enzyme and the kinin B2 receptor in the rabbit jugular vein: modulation of contractile response to bradykinin.

  Canadian journal of physiology and pharmacology 20020201

• Losartan attenuates endothelial hyperpermeability responses to VPF and high glucose but not angiotensin II.

  Diabetologia 20020201

• Losartan reduces massive proteinuria in kidney transplant patients: a pilot study.

  Transplantation proceedings 20020201

• Fixed low-dose combination in first-line treatment of hypertension.

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20020201

• [Effect of losartan on arterial blood pressure and unit discharging of neurons in LHb and MHb of rat].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20020201

• [Stress intolerance in diastolic dysfunction. A case for AT1 blocker?].

  MMW Fortschritte der Medizin 20020117

• Angiotensin-(1-7) reverts the stimulatory effect of angiotensin II on the proximal tubule Na(+)-ATPase activity via a A779-sensitive receptor.

  Regulatory peptides 20020115

• The brain renin-angiotensin system in transgenic mice carrying a highly regulated human renin transgene.

  Circulation research 20020111

• Chronic effects of endothelin 1 and angiotensin II on gap junctions and intercellular communication in cardiac cells.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020101

• Endogenous angiotensin modulates PGE(2)-mediated release of substance P from renal mechanosensory nerve fibers.

  American journal of physiology. Regulatory, integrative and comparative physiology 20020101

• Chronic hypotensive effects of losartan are not dependent on the actions of angiotensin II at AT 2 receptors.

  Journal of cardiovascular pharmacology 20020101

• Are angiotensin II receptor blockers indicated in chronic heart failure?

  Heart (British Cardiac Society) 20020101

• Differential effect of angiotensin II on blood circulation in the renal medulla and cortex of anaesthetised rats.

  The Journal of physiology 20020101

• Effect of combining an ACE inhibitor and an angiotensin II receptor blocker on plasma and kidney tissue angiotensin II levels.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20020101

• Combined use of enalapril and losartan to reduce proteinuria: a question of safety.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20020101

• Androgen dependent expression of AT1 receptor and its regulation of anion secretion in rat epididymis.

  Cell biology international 20020101

• Induction of p27KIP1 after unilateral ureteral obstruction is independent of angiotensin II.

  Kidney international 20020101

• Angiotensin AT(1) receptor signalling modulates reparative angiogenesis induced by limb ischaemia.

  British journal of pharmacology 20020101

• Treatment of scleroderma.

  Archives of dermatology 20020101

• Effects of losartan and its combination with quinapril on the cardiac sympathetic nervous system and neurohormonal status in essential hypertension.

  Journal of hypertension 20020101

• Stimulation of cardiac apoptosis in essential hypertension: potential role of angiotensin II.

  Hypertension (Dallas, Tex. : 1979) 20020101

• Angiotensin II and catecholamines increase plasma levels of 8-epi-prostaglandin F(2alpha) with different pressor dependencies in rats.

  Hypertension (Dallas, Tex. : 1979) 20020101

• Salt-sensitive hypertension resulting from nitric oxide synthase inhibition is associated with loss of regulation of angiotensin II in the rat.

  Experimental physiology 20020101

• Angiotensin II-induced drinking and pressor responses to central or systemic irbesartan and losartan.

  Pharmacology, biochemistry, and behavior 20020101

• Improving the managed care of hypertension with angiotensin II antagonists.

  The American journal of the medical sciences 20020101

• Effect of angiotensin-(1-7) on jejunal absorption of water in rats.

  Peptides 20020101

• Use of angiotensin-converting enzyme inhibitors in patients with diabetes and coronary artery disease.

  Current problems in cardiology 20020101

• Type 2 diabetes: RENAAL and IDNT--the emergence of new treatment options.

  Journal of clinical hypertension (Greenwich, Conn.) 20020101

• Comparative angiotensin II receptor blockade in healthy volunteers: the importance of dosing.

  Clinical pharmacology and therapeutics 20020101

• Pharmacokinetics of losartan and its metabolite E-3174 in relation to the CYP2C9 genotype.

  Clinical pharmacology and therapeutics 20020101

• A comparative trial of controlled-onset, extended-release verapamil, enalapril, and losartan on blood pressure and heart rate changes.

  American journal of hypertension 20020101

• Role of central angiotensin II receptors in cold-induced hypertension.

  American journal of hypertension 20020101

• Clinical trials of angiotensin receptor blockers in heart failure: what do we know and what will we learn?

  American journal of hypertension 20020101

• Use of angiotensin II receptor blockers in animal models of atherosclerosis.

  American journal of hypertension 20020101

• Preventing nephropathy in patients with type 2 diabetes.

  Managed care interface 20020101

• Application of capillary zone electrophoresis to the screening of some angiotensin II receptor antagonists.

  Electrophoresis 20020101

• Comparison of the effects of amlodipine and losartan on 24-hour ambulatory blood pressure in hypertensive patients.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20020101

• Evidence for modulation of pericryptal sheath myofibroblasts in rat descending colon by transforming growth factor beta and angiotensin II.

  BMC gastroenterology 20020101

• [Effect of long-term treatment with enalapril, losartan and their combination on the quality of life of patients with congestive heart failure].

  Terapevticheskii arkhiv 20020101

• Can angiotensin receptor antagonists be used safely in patients with previous ACE inhibitor-induced angioedema?

  Drug safety 20020101

• [The best of 2001. Arterial hypertension].

  Archives des maladies du coeur et des vaisseaux 20020101

• Locally synthesized angiotensin modulates pineal melatonin generation.

  Journal of neurochemistry 20020101

• Effects of angiotensin II receptor antagonist on endothelial vasomotor function and urinary albumin excretion in type 2 diabetic patients with microalbuminuria.

  Diabetes/metabolism research and reviews 20020101

• The potential economic consequences of cognitive improvement with losartan.

  Blood pressure 20020101

• The effect of a losartan-based treatment regimen on isolated systolic hypertension.

  Journal of clinical hypertension (Greenwich, Conn.) 20020101

• Candesartan cilexetil plus hydrochlorothiazide combination: a review of its use in hypertension.

  Drugs 20020101

• One-week losartan administration increases sodium excretion in cirrhotic patients with and without ascites.

  Journal of gastroenterology 20020101

• Does angiotensin II type 1 receptor blockade offer a clinical advantage to cirrhotics with ascites?

  Journal of gastroenterology 20020101

• Losartan-induced hepatic injury.

  Journal of clinical gastroenterology 20020101

• [Efficacy-safety relationship of AT1 angiotensin II receptor antagonists: current data].

  La Clinica terapeutica 20020101

• Angiotensin II receptor polymorphisms in hypertension. Pharmacogenomic considerations.

  Pharmacogenomics 20020101

• Losartan decreases glomerular filtration rate in isolated perfused porcine slaughterhouse kidneys.

  Alternatives to laboratory animals : ATLA 20020101

• Chronic beneficial effects of type 1 angiotensin II receptor antagonist in patients with chronic hypoxemic pulmonary diseases.

  Cardiology 20020101

• [Effects of long-term therapy with losartan on baroreflex regulation of cardiovascular system].

  Klinicheskaia meditsina 20020101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20020101

• Losartan was renoprotective in diabetic nephropathy independent of its effect on blood pressure.

  ACP journal club 20020101

• Neuron-specific expression of human angiotensinogen in brain causes increased salt appetite.

  Physiological genomics 20020101

• Candesartan cilexetil: an update of its use in essential hypertension.

  Drugs 20020101

• Role of angiotensin II receptors in the regulation of vasomotor neurons in the ventrolateral medulla.

  Clinical and experimental pharmacology & physiology 20020101

• The choice of antihypertensive drugs in patients with erectile dysfunction.

  Current medical research and opinion 20020101

• [AT(1) and AT(2) angiotensin II receptors: key features].

  Drugs 20020101

• Effects of losartan, somatostatin and losartan plus somatostatin on portal hemodynamics and renal functions in cirrhosis.

  Hepato-gastroenterology 20020101

• Olmesartan medoxomil.

  Drugs 20020101

• [Effect of antihypertensive combinations on arterial pressure, albuminuria, and glycemic control in patients with type II diabetic nephropathy: a randomized study].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20020101

• [Uricemia-lowering activity of losartan in kidney transplantation].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20020101

• The role of losartan in cost-effective hypertension control.

  Current medical research and opinion 20020101

• [The activity of angiotensin converting enzyme in vascular mesenteric bed of rats poisoned with lead and cadmium].

  Medycyna pracy 20020101

• Losartan and diabetic nephropathy: commentaries on the RENAAL study.

  Cardiovascular diabetology 20020101

• [Respiratory and renal functions and blood electrolytic composition in patients with pulmonary tuberculosis in the treatment of heart failure].

  Problemy tuberkuleza 20020101

• [Clinico-hematological effectiveness in losartan for treating hypertensive patients].

  Likars'ka sprava 20020101

• The Losartan Intervention for Endpoint Reduction (LIFE) trial-have angiotensin-receptor blockers come of age?

  Journal of clinical hypertension (Greenwich, Conn.) 20020101

• Renoprotective effect of small doses of losartan and enalapril in patients with primary glomerulonephritis. Short-term observation.

  American journal of nephrology 20020101

• Protection of the cardiovascular system by imidapril, a versatile angiotensin-converting enzyme inhibitor.

  Cardiovascular drug reviews 20020101

• Effects of a long-term pharmacological interruption of the renin-angiotensin system on the fibrinolytic system in essential hypertension.

  Pathophysiology of haemostasis and thrombosis 20020101

• Angiotensin II increases intracellular calcium concentration in pig endometrial stromal cells through type 1 angiotensin receptors, but does not stimulate phospholipase C activity or prostaglandin F2alpha secretion.

  Reproduction, fertility, and development 20020101

• Comparison of losartan with ACE inhibitors and dihydropyridine calcium channel antagonists: a pilot study of prescription-event monitoring in Japan.

  Drug safety 20020101

• Effect of angiotensin-converting enzyme inhibitors on liver regeneration in rats.

  Hepato-gastroenterology 20020101

• Inhibitors of the renin-angiotensin system reduce the rate of GFR decline and end-stage renal disease in patients with severe renal insufficiency.

  Journal of nephrology 20020101

• Influence of AT1 receptor blockade on blood pressure, renal haemodynamics and hormonal responses to intravenous angiotensin II infusion in hypertensive patients.

  Blood pressure 20020101

• Does the angiotensin II receptor antagonist losartan improve cognitive function?

  Drugs & aging 20020101

• Effect of losartan, an angiotensin II antagonist, on secondary biliary cirrhosis.

  Hepato-gastroenterology 20020101

• Interactions between antiretroviral drugs and drugs used for the therapy of the metabolic complications encountered during HIV infection.

  Clinical pharmacokinetics 20020101

• [Policy of antihypertensive therapy in arterial hypertension in the elderly. II].

  Klinicheskaia meditsina 20020101

• Losartan reduced strokes and new-onset diabetes more than atenolol in essential hypertension.

  ACP journal club 20020101

• Losartan reduced cardiovascular morbidity and mortality more than atenolol in patients with diabetes and essential hypertension.

  ACP journal club 20020101

• Kinetic analysis for multiple substrate interaction at the active site of cytochrome P450.

  Methods in enzymology 20020101

• The relationships between dose and antihypertensive effect of four AT1-receptor blockers. Differences in potency and efficacy.

  Blood pressure 20020101

• Long-term efficacy and tolerability of telmisartan as monotherapy and in combination with other antihypertensive medications.

  Blood pressure 20020101

• Sexual dysfunction in patients with hypertension: implications for therapy.

  Journal of clinical hypertension (Greenwich, Conn.) 20020101

• A review of olmesartan medoxomil monotherapy: antihypertensive efficacy similar to that of other angiotensin II receptor blocker/hydrochlorothiazide combinations?

  Congestive heart failure (Greenwich, Conn.) 20020101

• Renal nuclear angiotensin II receptors in normal and hypertensive rats.

  Acta physiologica Hungarica 20020101

• [Is it real to replace angiotensin converting enzyme inhibitors as basic remedy in the treatment of chronic heart failure?].

  Kardiologiia 20020101

• [Clinical hypertensiology: analysis of trials completed in 2001-2002].

  Kardiologiia 20020101

• Can losartan improve cardiac performance during the treadmill exercise test in hypertensive subjects?

  Drugs under experimental and clinical research 20020101

• Angiotensin receptor antagonists in patients with nephropathy due to type 2 diabetes.

  Annals of medicine 20020101

• Effect of chronic treatment with losartan on streptozotocin induced diabetic rats.

  Indian journal of experimental biology 20020101

• [Stability of neurohumoral effects of losartan combined with metoprolol in chronic cardiac low output].

  Likars'ka sprava 20020101

• Effects of combination of cyclosporine with losartan or enalapril on kidney function in uremic rats.

  Polish journal of pharmacology 20020101

• Long-term effects of losartan on proteinuria and renal function in patients with renal amyloidosis.

  Scandinavian journal of urology and nephrology 20020101

• Are angiotensin II receptor antagonists indicated in chronic heart failure?

  Heart failure monitor 20020101

• Assessment of effect of angiotensin II receptor antagonist losartan on aortic distensibility in patients with essential hypertension by echocardiography.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20020101

• Search of antimicrobial activity of selected non-antibiotic drugs.

  Acta poloniae pharmaceutica 20020101

• Pepstatin A is inducing contractile effects on isolated rat aorta rings.

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20020101

• [Effects of angiotension II receptor antagonist on the level ET and NO in the patients with renal hypertension and protection of renal function].

  Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20011228

• In vitro evidence for an intracellular site of angiotensin action.

  Circulation research 20011207

• AT(1)-receptor blockade in the hypothalamic PVN reduces central hyperosmolality-induced renal sympathoexcitation.

  American journal of physiology. Regulatory, integrative and comparative physiology 20011201

• Isoproterenol-induced cardiac hypertrophy: role of circulatory versus cardiac renin-angiotensin system.

  American journal of physiology. Heart and circulatory physiology 20011201

• Angiotensin II inhibits and alters kinetics of voltage-gated K(+) channels of rat arterial smooth muscle.

  American journal of physiology. Heart and circulatory physiology 20011201

• Thromboxane receptor density is increased in human cardiovascular disease with evidence for inhibition at therapeutic concentrations by the AT(1) receptor antagonist losartan.

  British journal of pharmacology 20011201

• Effects of losartan in patients with a systemically functioning morphologic right ventricle after atrial repair of transposition of the great arteries.

  The American journal of cardiology 20011201

• Optimal antiproteinuric dose of losartan in nondiabetic patients with nephrotic range proteinuria.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20011201

• Regulation of vascular proteoglycan synthesis by angiotensin II type 1 and type 2 receptors.

  Journal of the American Society of Nephrology : JASN 20011201

• In situ demonstration of angiotensin-dependent and independent pathways for hyperaldosteronism during chronic extracellular fluid volume depletion.

  Molecular endocrinology (Baltimore, Md.) 20011201

• A method for the identification of pseudorabies virus protein and angiotensin AT(1A) receptor mRNA expression in the same CNS neurons.

  Brain research. Brain research protocols 20011201

• Does losartan (Cozaar) slow the progression of renal disease in patients with type 2 diabetes and nephropathy?

  The Journal of family practice 20011201

• Diverse effects of chronic treatment with losartan, fosinopril, and amlodipine on apoptosis, angiotensin II in the left ventricle of hypertensive rats.

  International journal of cardiology 20011201

• Angiotensin type 2 receptor-mediated hypotension in angiotensin type-1 receptor-blocked rats.

  Hypertension (Dallas, Tex. : 1979) 20011201

• Radial artery flow-mediated dilatation in heart failure patients: effects of pharmacological and nonpharmacological treatment.

  Hypertension (Dallas, Tex. : 1979) 20011201

• Angiotensin II promotes the phosphorylation of cyclic AMP-responsive element binding protein (CREB) at Ser133 through an ERK1/2-dependent mechanism.

  Journal of neurochemistry 20011201

• Antihypertensive therapy in critical occupations: studies with an angiotensin II antagonist.

  Aviation, space, and environmental medicine 20011201

• The protective effect of blocking angiotensin in both type I and type II diabetics with nephropathy.

  Journal of human hypertension 20011201

• Maximal exercise capacity is related to cardiovascular structure in patients with longstanding hypertension. A LIFE substudy. Losartan Intervention For Endpoint-Reduction in Hypertension.

  American journal of hypertension 20011201

• Effect of chronic angiotensin II type I receptor antagonism and angiotensin converting enzyme inhibition on plasma fibrinolytic variables in patients with heart failure.

  Thrombosis and haemostasis 20011201

• Effect of angiotensin type I-receptor blockade on left ventricular remodeling in pressure overload hypertrophy.

  Journal of cardiac failure 20011201

• Angiotensin receptor blockade in the anterior hypothalamic area inhibits stress-induced pressor responses in rats.

  Brain research bulletin 20011201

• Four-Year persistence patterns among patients initiating therapy with the angiotensin II receptor antagonist losartan versus other artihypertensive drug classes.

  Clinical therapeutics 20011201

• [Losartan and the kidney protection. The RENAAL study].

  Recenti progressi in medicina 20011201

• [Evidence-based therapy of systemic sclerosis].

  Zeitschrift fur Rheumatologie 20011201

• The role of CYP2C9 genotype in the metabolism of diclofenac in vivo and in vitro.

  European journal of clinical pharmacology 20011201

• Efficacy of ACE inhibitors and ATII receptor blockers in patients with microalbuminuria: a prospective study.

  Acta diabetologica 20011201

• Losartan may modulate erythropoietin production.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20011201

• Interactions between sodium and angiotensin.

  Clinical and experimental pharmacology & physiology 20011201

• Losartan modifies glomerular hyperfiltration and insulin sensitivity in type 1 diabetes.

  Diabetes, obesity & metabolism 20011201

• [Effects of angiotensin II on the 3H-TdR incorporation and synthesis of collagen in cultured bovine trabecular meshwork cells].

  Yan ke xue bao = Eye science 20011201

• [Comparative effects of carvedilol, losartan and their combination in preventing left ventricular remodeling after acute myocardial infarction in rats].

  Zhonghua nei ke za zhi 20011201

• Intracellular angiotensin II inhibits heterologous receptor stimulated Ca2+ entry.

  Life sciences 20011130

• Angiotensin II inhibits insulin-stimulated phosphorylation of eukaryotic initiation factor 4E-binding protein-1 in proximal tubular epithelial cells.

  The Biochemical journal 20011115

• Angiotensin-Il-receptor blockers and nephropathy in patients with type 2 diabetes.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20011113

• [Angiotensin II receptor antagonists reduce the development of nephropathies in type 2 diabetes. Three new studies are of interest, but don't answer all questions].

  Lakartidningen 20011107

• Effects of losartan in combination with or without exercise on insulin resistance in Otsuka Long-Evans Tokushima Fatty rats.

  European journal of pharmacology 20011102

• Losartan inhibits the angiotensin II-induced modifications on fibrinolysis and matrix deposition by primary human vascular smooth muscle cells.

  Journal of cardiovascular pharmacology 20011101

• Hypertensive pulmonary oedema is due to diastolic dysfunction.

  European heart journal 20011101

• Novel role of macrophage migration inhibitory factor in angiotensin II regulation of neuromodulation in rat brain.

  Endocrinology 20011101

• Neural and hormonal control of arterial pressure during cold exposure in unanesthetized week-old rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20011101

• Losartan prevents contractile dysfunction in rat myocardium after left ventricular myocardial infarction.

  American journal of physiology. Heart and circulatory physiology 20011101

• Effects of combined administration of ACE inhibitor and angiotensin II receptor antagonist are prevented by a high NaCl intake.

  Journal of hypertension 20011101

• Drug companies should not have the final say in the design of clinical trials.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20011101

• Potentiation of bradykinin-induced tissue plasminogen activator release by angiotensin-converting enzyme inhibition.

  Journal of the American College of Cardiology 20011101

• Selective potentiation of N-type calcium channels by angiotensin II in rat subfornical organ neurones.

  The Journal of physiology 20011101

• Corpuscles of Stannius secrete renin or an isorenin that regulates cardiovascular function in freshwater North American eels, Anguilla rostrata LeSueur.

  General and comparative endocrinology 20011101

• Angiotensin II enhances tubuloglomerular feedback via luminal AT(1) receptors on the macula densa.

  Kidney international 20011101

• Effects of losartan/diuretic combination treatment on serum uric acid levels in hypertensive patients.

  The American journal of cardiology 20011101

• Blockade of angiotensin receptor subtypes in arcuate uterine artery of pregnant and postpartum rats.

  Hypertension (Dallas, Tex. : 1979) 20011101

• Angiotensin II via activation of type 1 receptor upregulates expression of endoglin in human coronary artery endothelial cells.

  Hypertension (Dallas, Tex. : 1979) 20011101

• Improvement in insulin sensitivity by losartan in non-insulin-dependent diabetic (NIDDM) rats.

  Pharmacological research 20011101

• AT1 receptor is present in glioma cells; its blockage reduces the growth of rat glioma.

  British journal of cancer 20011101

• Endothelial factors and microvascular hypertensive disease.

  Journal of cardiovascular pharmacology 20011101

• Angiotensin II receptor blockers for the treatment of hypertension.

  Expert opinion on pharmacotherapy 20011101

• Clinical benefit of very-low-dose perindopril-indapamide combination in hypertension.

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20011101

• A comparative evaluation of therapeutic effects of once a day dose of losartan potassium versus enalapril maleate in mild to moderate essential hypertension.

  Journal of the Indian Medical Association 20011101

• [Contrast of losartan, fosinopril and amlodipine on cardiomyocyte apoptosis and left ventricular remolding in hypertensive rats].

  Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20011028

• Identification and characterization of functional angiotensin II type 1 receptors on immortalized human fetal aortic vascular smooth muscle cells.

  Molecular and cellular endocrinology 20011025

• [Angiotensin II antagonist also protects the kidneys. 2 dialysis-free years for diabetics].

  MMW Fortschritte der Medizin 20011025

• Increased AT(1) receptors in adrenal gland of AT(2) receptor gene-disrupted mice.

  Regulatory peptides 20011015

• Renal protection by angiotensin II receptor antagonists in patients with type 2 diabetes.

  The Medical journal of Australia 20011015

• Angiotensin II type 1 receptor blockers and congestive heart failure.

  Circulation 20011009

• The role of activation of the renin-angiotensin system on the reflex regional vasoconstriction caused by distension of the uterus in anaesthetized pigs.

  Autonomic neuroscience : basic & clinical 20011008

• pK(a) determination of angiotensin II receptor antagonists (ARA II) by spectrofluorimetry.

  Journal of pharmaceutical and biomedical analysis 20011001

• Redox-sensitive intermediates mediate angiotensin II-induced p38 MAP kinase activation, AP-1 binding activity, and TGF-beta expression in adult ventricular cardiomyocytes.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011001

• Effects of ANG II on bradykinin receptor gene expression in cardiomyocytes and vascular smooth muscle cells.

  American journal of physiology. Heart and circulatory physiology 20011001

• Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia.

  The Journal of endocrinology 20011001

• Hyperglycemia activates p53 and p53-regulated genes leading to myocyte cell death.

  Diabetes 20011001

• Angiotensin II receptor blockers and nephropathy trials.

  Diabetes care 20011001

• Angiotensin type 1 receptor antagonism reverses abnormal coronary vasomotion in atherosclerosis.

  Journal of the American College of Cardiology 20011001

• T-lymphocyte and plasma angiotensin-converting enzyme activity during enalapril and losartan administration in humans.

  Journal of cardiovascular pharmacology 20011001

• Inhibitory effect of losartan on laser-induced choroidal neovascularization in rats.

  American journal of ophthalmology 20011001

• Comparative effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricaemia and gout.

  Journal of hypertension 20011001

• Renal protective effects of chronic exercise and antihypertensive therapy in hypertensive rats with chronic renal failure.

  Journal of hypertension 20011001

• Relation of QT interval and QT dispersion to echocardiographic left ventricular hypertrophy and geometric pattern in hypertensive patients. The LIFE study. The Losartan Intervention For Endpoint Reduction.

  Journal of hypertension 20011001

• [Effect of losartan on renal and cardiovascular complications of patients with type 2 diabetes and nephropathy].

  Ugeskrift for laeger 20011001

• Antagonism of AT2 receptors augments angiotensin II-induced abdominal aortic aneurysms and atherosclerosis.

  British journal of pharmacology 20011001

• Effects of centrally administered losartan on deoxycorticosterone-salt hypertension rats.

  Journal of Korean medical science 20011001

• Losartan attenuates symptomatic and hormonal responses to hypoglycemia in humans.

  Clinical pharmacology and therapeutics 20011001

• [Review of randomized trials of angiotensin receptor blockers in the treatment of patients with congestive heart failure].

  Nihon rinsho. Japanese journal of clinical medicine 20011001

• Influence of the angiotensin II receptor antagonist losartan on diuretic-induced metabolic effects in elderly hypertensive patients: comparison with a calcium channel blocker.

  International journal of clinical pharmacology and therapeutics 20011001

• Losartan increases renal blood flow during isoflurane anesthesia in sheep.

  Acta anaesthesiologica Scandinavica 20011001

• Peripheral administration of AT1 receptor blockers and pressor responses to central angiotensin II and sodium.

  Canadian journal of physiology and pharmacology 20011001

• Effect of losartan on circulating TNFalpha levels and left ventricular systolic performance in patients with heart failure.

  Journal of cardiovascular risk 20011001

• Effect of chronic treatment with losartan on streptozotocin induced diabetic nephropathy.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20011001

• Autonomic function and baroreflex sensitivity during angiotensin-converting enzyme inhibition or angiotensin II AT-1 receptor blockade in essential hypertensive patients.

  Acta cardiologica 20011001

• [Clinical study of the month. Nephroprotective role of angiotensin II receptor antagonists in type 2 diabetes: results of the IDNT and RENAAL trials].

  Revue medicale de Liege 20011001

• Angioedema associated with angiotensin II receptor antagonists: challenging our knowledge of angioedema and its etiology.

  The Laryngoscope 20011001

• [Angiotensin II in rostral ventrolateral medulla mediates amino acids release from spinally projecting nerve terminals in the spinal cord].

  Sheng li xue bao : [Acta physiologica Sinica] 20011001

• [Severe pustular and polymorphous vasculitis caused by losartan].

  Annales de dermatologie et de venereologie 20011001

• [Estimation of blood pressure, selected biochemical parameters and indices of left ventricular heart function in patients with mild or moderate essential hypertension treated with potassium losartan].

  Polskie Archiwum Medycyny Wewnetrznej 20011001

• Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy.

  The New England journal of medicine 20010920

• New method of cardiac output measurement using ultrasound velocity dilution in rats.

  Journal of applied physiology (Bethesda, Md. : 1985) 20010901

• Angiotensin IV enhances LTP in rat dentate gyrus in vivo.

  Peptides 20010901

• Angiotensin II and VEGF are involved in angiogenesis induced by short-term exercise training.

  American journal of physiology. Heart and circulatory physiology 20010901

• ANG II in median preoptic nucleus and pressor responses to CSF sodium and high sodium intake in SHR.

  American journal of physiology. Heart and circulatory physiology 20010901

• Combined treatment with mycophenolate mofetil and an angiotensin II receptor antagonist fully protects from chronic rejection in a rat model of renal allograft.

  Journal of the American Society of Nephrology : JASN 20010901

• Differential regulation of thrombospondin-1 and fibronectin by angiotensin II receptor subtypes in cultured endothelial cells.

  Cardiovascular research 20010901

• Influence of the renin-angiotensin system on epidermal growth factor expression in normal and cyclosporine-treated rat kidney.

  Kidney international 20010901

• Renin-angiotensin system is involved in the mechanism of increased serum asymmetric dimethylarginine in essential hypertension.

  Japanese circulation journal 20010901

• Angiotensin II administration to atherosclerotic mice increases macrophage uptake of oxidized ldl: a possible role for interleukin-6.

  Arteriosclerosis, thrombosis, and vascular biology 20010901

• Adrenergic and endothelin B receptor-dependent hypertension in dopamine receptor type-2 knockout mice.

  Hypertension (Dallas, Tex. : 1979) 20010901

• Role of angiotensin II and free radicals in blood pressure regulation in a rat model of renal hypertension.

  Hypertension (Dallas, Tex. : 1979) 20010901

• Differential subcellular actions of ACE inhibitors and AT(1) receptor antagonists on cardiac remodeling induced by chronic inhibition of NO synthesis in rats.

  Hypertension (Dallas, Tex. : 1979) 20010901

• Chronic AT(1) receptor blockade alters autonomic balance and sympathetic responses in hypertension.

  Hypertension (Dallas, Tex. : 1979) 20010901

• Angiotensin II type AT(2) receptor mRNA expression and renal vasodilatation are increased in renal failure.

  Hypertension (Dallas, Tex. : 1979) 20010901

• Renal vascular effects of frusemide in the rat: influence of salt loading and the role of angiotensin II.

  Experimental physiology 20010901

• Effect of losartan on sodium appetite of hypothyroid rats subjected to water and sodium depletion and water, sodium and food deprivation.

  Experimental physiology 20010901

• [Complications in kidney transplantation].

  Presse medicale (Paris, France : 1983) 20010901

• Differentiation in the angiotensin II receptor 1 blocker class on autonomic function.

  Current hypertension reports 20010901

• Interaction between sodium intake, angiotensin II, and blood pressure as a cause of cardiac hypertrophy.

  American journal of hypertension 20010901

• Differential effects of ACE-inhibition and angiotensin II antagonism on fibrinolysis and insulin sensitivity in hypertensive postmenopausal women.

  American journal of hypertension 20010901

• The role of losartan in the management of patients with heart failure.

  Clinical therapeutics 20010901

• Angiotensins II and IV stimulate the rat adrenocortical cell proliferation acting via different receptors.

  Endocrine regulations 20010901

• Effects of losartan on blood pressure and humoral factors in a patient who suffered from anaphylactoid reactions when treated with ACE inhibitors during LDL apheresis.

  Hypertension research : official journal of the Japanese Society of Hypertension 20010901

• Effects of low-dose losartan treatment on persistent microalbuminuria in normotensive type 1 diabetic subjects.

  Journal of endocrinological investigation 20010901

• The effect of Losartan on insulin resistance and beta cell function in chronic hemodialysis patients.

  Renal failure 20010901

• Does angiotensin II receptor antagonist Losartan suppress drinking behavior in hemodialysis patients?

  Renal failure 20010901

• [The role of AT1 receptor and cyclin kinase inhibitor p27 protein in angiotensin II-induced hypertrophy of mesangial cell].

  Zhonghua nei ke za zhi 20010901

• Renoprotection in Type 2 diabetes: blockade of the renin-angiotensin system with angiotensin II receptor blockers.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20010901

• Uricosuric effect of losartan in patients with renal transplants.

  Transplantation 20010827

• Cardioprotective effects of ramipril and losartan in right ventricular pressure overload in the rabbit: importance of kinins and influence on angiotensin II type 1 receptor signaling pathway.

  Circulation 20010821

• Elevated blood pressure in transgenic mice with brain-specific expression of human angiotensinogen driven by the glial fibrillary acidic protein promoter.

  Circulation research 20010817

• Impaired angiotensin II regulation of renal C-type natriuretic peptide mRNA expression in experimental diabetes mellitus.

  Cardiovascular research 20010815

• Comparison of the effects of enalapril and losartan on posttransplantation erythrocytosis in renal transplant recipients: prospective randomized study.

  Transplantation 20010815

• Identification of angiotensin II type 2 (AT2) receptor domains mediating high-affinity CGP 42112A binding and receptor activation.

  The Journal of pharmacology and experimental therapeutics 20010801

• Angiotensin II AT(2) receptors inhibit growth responses in proximal tubule cells.

  American journal of physiology. Renal physiology 20010801

• Angiotensin II and prostaglandin interactions on systemic and renal effects of L-NAME in humans.

  Journal of the American Society of Nephrology : JASN 20010801

• Angiotensin II promotes glucose-induced activation of cardiac protein kinase C isozymes and phosphorylation of troponin I.

  Diabetes 20010801

• Effect of grapefruit juice on the pharmacokinetics of losartan and its active metabolite E3174 in healthy volunteers.

  Therapeutic drug monitoring 20010801

• Structural changes in the kidney induced by coarctation hypertension.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20010801

• Role of angiotensin II type 1 receptor in the regulation of cellular adhesion molecules in atherosclerosis.

  American heart journal 20010801

• Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of MAPKs after angiotensin II stimulation.

  Journal of neurochemistry 20010801

• Randomized comparison of long-term losartan versus propranolol in lowering portal pressure in cirrhosis.

  Gastroenterology 20010801

• Similar effects of isolated systolic and combined hypertension on left ventricular geometry and function: the LIFE Study.

  American journal of hypertension 20010801

• Relation of echocardiographic left ventricular mass and hypertrophy to persistent electrocardiographic left ventricular hypertrophy in hypertensive patients: the LIFE Study.

  American journal of hypertension 20010801

• Cardiac nitric oxide production due to angiotensin-converting enzyme inhibition decreases beta-adrenergic myocardial contractility in patients with dilated cardiomyopathy.

  Journal of the American College of Cardiology 20010801

• Relationship of the electrocardiographic strain pattern to left ventricular structure and function in hypertensive patients: the LIFE study. Losartan Intervention For End point.

  Journal of the American College of Cardiology 20010801

• Calcium-channel blockers for Raynaud's phenomenon in systemic sclerosis.

  Arthritis and rheumatism 20010801

• Effect of dietary sodium intake on the responses to bicuculline in the paraventricular nucleus of rats.

  Hypertension (Dallas, Tex. : 1979) 20010801

• Effect of chronic angiotensin II inhibition on the nitric oxide synthase in the normal rat during aging.

  Journal of hypertension 20010801

• Blood pressure-independent effect of angiotensin AT1 receptor blockade on renal endothelin-1 production in hypertensive uremic rats.

  Journal of hypertension 20010801

• Schönlein-Henoch purpura associated with losartan treatment and presence of antineutrophil cytoplasmic antibodies of x specificity.

  The British journal of dermatology 20010801

• Losartan versus valsartan in the treatment of patients with mild to moderate essential hypertension: data from a multicenter, randomized, double-blind, 12-week trial.

  Clinical therapeutics 20010801

• Antihypertensive efficacy and safety of losartan alone and in combination with hydrochlorothiazide in adult African Americans with mild to moderate hypertension.

  Clinical therapeutics 20010801

• [Role of AT1 receptors in functional adaptation to ischemia-reperfusion in solated rat hearts in relationship to oxidative stress].

  Archives des maladies du coeur et des vaisseaux 20010801

• [In contrast to captopril and enalapril, losartan does not increase mortality of gerbils after carotid ligation].

  Archives des maladies du coeur et des vaisseaux 20010801

• Effects of losartan on the collagen degradative enzymes in hypertrophic and congestive types of cardiomyopathic hamsters.

  Molecular and cellular biochemistry 20010801

• Fetal toxic effects and angiotensin-II-receptor antagonists.

  Lancet (London, England) 20010721

• Usefulness of serum carboxy-terminal propeptide of procollagen type I in assessment of the cardioreparative ability of antihypertensive treatment in hypertensive patients.

  Circulation 20010717

• Experimental design methodologies to optimise the spectrofluorimetric determination of Losartan and Valsartan in human urine.

  Talanta 20010706

• Biomechanical strain induces class a scavenger receptor expression in human monocyte/macrophages and THP-1 cells: a potential mechanism of increased atherosclerosis in hypertension.

  Circulation 20010703

• Regulation of angiotensin II-stimulated osteopontin expression in cardiac microvascular endothelial cells: role of p42/44 mitogen-activated protein kinase and reactive oxygen species.

  Journal of cellular physiology 20010701

• Combined angiotensin converting enzyme inhibition and angiotensin AT(1) receptor blockade up-regulates myocardial AT(2) receptors in remodeled myocardium post-infarction.

  Cardiovascular research 20010701

• Differential ANG II-induced growth activation pathways in mesenteric artery smooth muscle cells from SHR.

  American journal of physiology. Heart and circulatory physiology 20010701

• Role of CYP2C9 polymorphism in losartan oxidation.

  Drug metabolism and disposition: the biological fate of chemicals 20010701

• Angiotensin receptor blockers for chronic heart failure and acute myocardial infarction.

  Heart (British Cardiac Society) 20010701

• In vivo visualization of angiotensin II- and tubuloglomerular feedback-mediated renal vasoconstriction.

  Kidney international 20010701

• Remission achieved in chronic nephropathy by a multidrug approach targeted at urinary protein excretion.

  Nephron 20010701

• Coadministration of losartan and enalapril exerts additive antiproteinuric effect in IgA nephropathy.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20010701

• IgA nephropathy and inhibitors of the renin angiotensin system: is reduction in proteinuria adequate proof of efficacy?

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20010701

• Both subtype 1 and 2 receptors of angiotensin II participate in regulation of intracellular calcium in glomerular epithelial cells.

  The Journal of laboratory and clinical medicine 20010701

• Effect of the AT1-receptor antagonists losartan, irbesartan, and telmisartan on angiotensin II-induced facilitation of sympathetic neurotransmission in the rat mesenteric artery.

  Journal of cardiovascular pharmacology 20010701

• Issues in hypertension: drug tolerability and special populations.

  American journal of hypertension 20010701

• Angiotensin receptor blockers -- finally the evidence is coming in: IDNT and RENAAL.

  International journal of cardiology 20010701

• Inhibition of baroreflex by angiotensin II via Fos expression in nucleus tractus solitarii of the rat.

  Hypertension (Dallas, Tex. : 1979) 20010701

• A forced titration study of antihypertensive efficacy of candesartan cilexetil in comparison to losartan: CLAIM Study II.

  Journal of human hypertension 20010701

• Does the antihypertensive response to angiotensin converting enzyme inhibition predict the antihypertensive response to angiotensin receptor antagonism?

  American journal of hypertension 20010701

• [Effect of losartan on antioxidant status in rats with diabetes mellitus].

  Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20010701

• Long-term effects of chromium, grape seed extract, and zinc on various metabolic parameters of rats.

  Molecular and cellular biochemistry 20010701

• Angiotensin receptor blocker losartan suppresses platelet activity by interfering with thromboxane signaling.

  Cardiovascular drugs and therapy 20010701

• Antihypertensive drugs that act on Renin-Angiotensin System with emphasis in AT(1) antagonists.

  Mini reviews in medicinal chemistry 20010701

• [Effects of losartan on renal ultrastructure in diabetic rats].

  Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20010628

• Random research.

  Circulation 20010626

• Angiotensin II subtype 1 receptor blockers and renal function.

  Archives of internal medicine 20010625

• Selective down-regulation of AT2 receptors in uterine arteries from pregnant ewes given 24-h intravenous infusions of angiotensin II.

  Regulatory peptides 20010615

• Comparison of effects of losartan versus enalapril on fibrinolysis and coagulation in patients with acute myocardial infarction.

  The American journal of cardiology 20010615

• Combined angiotensin II receptor antagonism and angiotensin-converting enzyme inhibition further attenuates postinfarction left ventricular remodeling.

  Circulation 20010612

• Ren1d and Ren2 cooperate to preserve homeostasis: evidence from mice expressing GFP in place of Ren1d.

  Physiological genomics 20010606

• Angiotensin II type 1 receptor regulation and differential trophic effects on rat cardiac myofibroblasts after acute myocardial infarction.

  Journal of cellular physiology 20010601

• Effect of angiotensin II on calcium reabsorption by the luminal membranes of the nephron.

  American journal of physiology. Endocrinology and metabolism 20010601

• Angiotensin II type 2 receptor-mediated duodenal mucosal alkaline secretion in the rat.

  American journal of physiology. Gastrointestinal and liver physiology 20010601

• Angiotensin IV induces tyrosine phosphorylation of focal adhesion kinase and paxillin in proximal tubule cells.

  American journal of physiology. Renal physiology 20010601

• Glucocorticoids potentiate central actions of angiotensin to increase arterial pressure.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010601

• Regional haemodynamic responses to the cannabinoid agonist, WIN 55212-2, in conscious, normotensive rats, and in hypertensive, transgenic rats.

  British journal of pharmacology 20010601

• IGF-1 overexpression inhibits the development of diabetic cardiomyopathy and angiotensin II-mediated oxidative stress.

  Diabetes 20010601

• Add-on angiotensin receptor blockade with maximized ACE inhibition.

  Kidney international 20010601

• Responses of fetal ovine systemic and umbilical arteries to angiotensin II.

  Pediatric research 20010601

• Dose-dependent blockade of the angiotensin II type 1 receptor with losartan in normal volunteers.

  Journal of cardiovascular pharmacology 20010601

• Postischemic apoptosis and functional recovery after angiotensin II type 1 receptor blockade in isolated working rat hearts.

  Journal of hypertension 20010601

• Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of pi*--pi* interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT(1) non-peptide antagonists.

  Bioorganic & medicinal chemistry 20010601

• Role of brain angiotensin II on somatosensory-induced antinatriuresis in hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 20010601

• Neural mechanisms subserving central angiotensinergic influences on plasma renin in sheep.

  Hypertension (Dallas, Tex. : 1979) 20010601

• Angiotensin II induces inward currents in subfornical organ neurones of rats.

  Journal of neuroendocrinology 20010601

• Differential activation of the STAT pathway by angiotensin II via angiotensin type 1 and type 2 receptors in cultured human fetal mesangial cells.

  Experimental and molecular pathology 20010601

• Pharmacoutilization of antihypertensive drugs: a model of analysis.

  International journal of clinical pharmacology and therapeutics 20010601

• In vitro and in vivo pharmacology of olmesartan medoxomil, an angiotensin II type AT1 receptor antagonist.

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20010601

• Relative efficacy of an angiotensin II antagonist compared with other antihypertensive agents. Olmesartan medoxomil versus antihypertensives.

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20010601

• The haemodynamic effects of losartan after right ventricle infarct in young pigs.

  Pharmacology & toxicology 20010601

• Central angiotensin and baroreceptor control of circulation.

  Annals of the New York Academy of Sciences 20010601

• Neurohumoral regulation in ischemia-induced heart failure. Role of the forebrain.

  Annals of the New York Academy of Sciences 20010601

• [Angiotensin II receptor antagonists: different or equivalent?].

  Presse medicale (Paris, France : 1983) 20010601

• Angiotensin II type 1 receptor modulation of L-type calcium currents in guinea-pig ventricular cells.

  Chinese medical journal 20010601

• The expression of AT1 receptor on hepatic stellate cells in rat fibrosis induced by CCl4.

  Chinese medical journal 20010601

• Angiotensin II receptor antagonists for the treatment of heart failure: what is their place after ELITE-II and Val-HeFT?

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20010601

• Non-AT(1)-receptor-mediated protective effect of angiotensin against acute ischaemic stroke in the gerbil.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20010601

• Effects of losartan treatment on T-cell activities and plasma leptin concentrations in primary hypertension.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20010601

• Effects of different durations of pretreatment with losartan on myocardial infarct size, endothelial function, and vascular endothelial growth factor.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20010601

• Effect of angiotensin II receptor antagonist and endothelin receptor antagonist on nitroglycerin tolerance in rats.

  Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20010601

• Chronic administration of losartan plus hydrochlorothiazide improves vascular status in young cardiomyopathic hamsters.

  European journal of pharmacology 20010525

• Angiotensin-II-receptor inhibitors in pregnancy.

  Lancet (London, England) 20010519

• Intracellular angiotensin II elicits Ca2+ increases in A7r5 vascular smooth muscle cells.

  European journal of pharmacology 20010518

• Acute and chronic alterations in blood pressure variability following experimental subarachnoid haemorrhage.

  Regulatory peptides 20010505

• Development of a high throughput equilibrium dialysis method.

  Journal of pharmaceutical sciences 20010501

• AT1 receptor block does not affect arterial baroreflex during pregnancy in rabbits.

  American journal of physiology. Heart and circulatory physiology 20010501

• Angiotensin II AT1 receptors preserve vasodilator reactivity in skeletal muscle resistance arteries.

  American journal of physiology. Heart and circulatory physiology 20010501

• Endothelial function during stimulation of renin-angiotensin system by low-sodium diet in humans.

  American journal of physiology. Heart and circulatory physiology 20010501

• Prothrombotic megakaryocyte and platelet changes in hypertension are reversed following treatment: a pilot study.

  Platelets 20010501

• Left ventricular function and hemodynamic features of inappropriate left ventricular hypertrophy in patients with systemic hypertension: the LIFE study.

  American heart journal 20010501

• The effect of ACE inhibitor and angiotensin II receptor antagonist therapy on serum uric acid levels and potassium homeostasis in hypertensive renal transplant recipients treated with CsA.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010501

• Suppression of experimental abdominal aortic aneurysms in the rat by treatment with angiotensin-converting enzyme inhibitors.

  Journal of vascular surgery 20010501

• Mechanisms of relaxation induced by angiotensin II in isolated canine and human uterine arteries.

  Journal of cardiovascular pharmacology 20010501

• Systemic infusion of angiotensin II into normal rats activates nuclear factor-kappaB and AP-1 in the kidney: role of AT(1) and AT(2) receptors.

  The American journal of pathology 20010501

• Chronotropic effect of angiotensin II via type 2 receptors in rat brain neurons.

  Journal of neurophysiology 20010501

• Differential effect of chronic antihypertensive treatment on vascular smooth muscle cell phenotype in spontaneously hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 20010501

• Losartan use in mild to moderate hypertension--adverse effects in moderate to severe renal failure.

  The Journal of the Association of Physicians of India 20010501

• Sexual dysfunction in hypertensive patients treated with losartan.

  The American journal of the medical sciences 20010501

• Effect of antihypertensive therapy using enalapril or losartan on haemostatic markers in essential hypertension: a pilot prospective randomised double-blind parallel group trial.

  International journal of cardiology 20010501

• Endothelial and myocyte apoptosis--role of angiotensin II.

  The Canadian journal of cardiology 20010501

• Differential effects of eprosartan and losartan at prejunctional angiotensin II receptors.

  Naunyn-Schmiedeberg's archives of pharmacology 20010501

• Exercise training causes skeletal muscle venular growth and alters hemodynamic responses in spontaneously hypertensive rats.

  Journal of hypertension 20010501

• Tolerability of antihypertensive drugs in a community-based setting.

  Clinical therapeutics 20010501

• Antihypertensive efficacy and tolerability of low-dose perindopril/indapamide combination compared with losartan in the treatment of essential hypertension.

  International journal of clinical practice 20010501

• Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure.

  Cardiology clinics 20010501

• Characterization of simple and reproducible vascular stenosis model in hypercholesterolemic hamsters.

  Lipids 20010501

• [Effects of lorsartan, fosinopril on myocardial fibrosis, angiotensin II and cardiac remolding in hypertensive rats].

  Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20010428

• Reactive oxygen species modulate angiotensin II-induced beta-myosin heavy chain gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in neonatal rat cardiomyocytes.

  Biochemical and biophysical research communications 20010427

• Angiotensin selectively activates a subpopulation of postganglionic sympathetic neurons in mice.

  Circulation research 20010427

• Atypical angiotensin receptors may mediate water intake induced by central injections of angiotensin II and of serotonin in pigeons.

  Regulatory peptides 20010420

• Gender differences in systolic left ventricular function in hypertensive patients with electrocardiographic left ventricular hypertrophy (the LIFE study).

  The American journal of cardiology 20010415

• Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice.

  The Journal of clinical investigation 20010415

• Angiotensin receptor in the heart of Bothrops jararaca snake.

  European journal of pharmacology 20010406

• Tonic suppression of spontaneous baroreceptor reflex by endogenous angiotensins via AT(2) subtype receptors at nucleus reticularis ventrolateralis in the rat.

  Synapse (New York, N.Y.) 20010401

• Angiotensin II stimulates cardiac L-type Ca(2+) current by a Ca(2+)- and protein kinase C-dependent mechanism.

  American journal of physiology. Heart and circulatory physiology 20010401

• The role of ANG II and endothelin-1 in exercise-induced diastolic dysfunction in heart failure.

  American journal of physiology. Heart and circulatory physiology 20010401

• Mechanisms of angiotensin-(1-7)-induced inhibition of angiogenesis.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010401

• Brain angiotensin receptors and sympathoadrenal regulation during insulin-induced hypoglycemia.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010401

• Determinants of terminal mesenteric artery resistance during the first postnatal month.

  American journal of physiology. Gastrointestinal and liver physiology 20010401

• Intracellular Angiotensin II and cell growth of vascular smooth muscle cells.

  British journal of pharmacology 20010401

• Angiotensin II receptor antagonist blocks the expression of connexin43 induced by cyclical mechanical stretch in cultured neonatal rat cardiac myocytes.

  Journal of molecular and cellular cardiology 20010401

• Effects of losartan and amlodipine on intrarenal hemodynamics and TGF-beta(1) plasma levels in a crossover trial in renal transplant recipients.

  Journal of the American Society of Nephrology : JASN 20010401

• Time course of the antiproteinuric and renal haemodynamic responses to losartan in microalbuminuric IDDM.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010401

• Modulation of oxidative stress by a selective inhibition of angiotensin II type 1 receptors in MI rats.

  Journal of the American College of Cardiology 20010401

• Inhibition of platelet activation in stroke-prone spontaneously hypertensive rats: comparison of losartan, candesartan, and valsartan.

  Journal of cardiovascular pharmacology 20010401

• KT3-671, an angiotensin AT1 receptor antagonist, attenuates vascular but not cardiac responses to sympathetic nerve stimulation in pithed rats.

  Journal of cardiovascular pharmacology 20010401

• Slowing the progression of renal disease in diabetic patients.

  The Annals of pharmacotherapy 20010401

• Sodium intake influences hemodynamic and neural responses to angiotensin receptor blockade in rostral ventrolateral medulla.

  Hypertension (Dallas, Tex. : 1979) 20010401

• Activation of NF-kappaB in tubular epithelial cells of rats with intense proteinuria: role of angiotensin II and endothelin-1.

  Hypertension (Dallas, Tex. : 1979) 20010401

• Expanded role for ARBs in cardiovascular and renal disease? Recent observations have far-reaching implications.

  Postgraduate medicine 20010401

• At receptor inhibition affects the noradrenaline sensitivity in isolated portal vein of normotensive rat.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20010401

• Angiotensin-converting enzyme inhibitors and AT1-receptor antagonist restore nitric oxide synthase (NOS) activity and neuronal NOS expression in the adrenal glands of spontaneously hypertensive rats.

  Japanese journal of pharmacology 20010401

• [Management of Raynaud's phenomenon].

  Annales de dermatologie et de venereologie 20010401

• Different types of antagonism by losartan and irbesartan on the effects of angiotensin II and its degradation products in rabbit arteries.

  Fundamental & clinical pharmacology 20010401

• Comparative effects of ACE inhibitors and an angiotensin receptor blocker on atherosclerosis and vascular function.

  Journal of cardiovascular pharmacology and therapeutics 20010401

• Effect of chronic AT(1) receptor antagonism on postischemic functional recovery and AT(1)/AT(2) receptor proteins in isolated working rat hearts.

  Journal of cardiovascular pharmacology and therapeutics 20010401

• Long-term treatment with enalapril or losartan does not show antiproliferative effects in peripheral blood mononuclear cells.

  Methods and findings in experimental and clinical pharmacology 20010401

• Effect of short-term losartan treatment in patients with primary aldosteronism and essential hypertension.

  Methods and findings in experimental and clinical pharmacology 20010401

• Attenuation of tissue P-selectin and MCP-1 expression and intimal proliferation by AT(1) receptor blockade in hyperlipidemic rabbits.

  Biochemical and biophysical research communications 20010330

• Efficacy and safety of losartan/hydrochlorothiazide in patients with severe hypertension.

  The American journal of cardiology 20010315

• Comparison of baseline data, initial course, and management: losartan versus captopril following acute myocardial infarction (The OPTIMAAL Trial). OPTIMAAL Trial Steering Committee and Investigators. Optimal Trial in Myocardial Infarction with the Angiotensin II Antagonist Losartan.

  The American journal of cardiology 20010315

• Plasma levels of vascular endothelial growth factor and its soluble receptor (SFlt-1) in essential hypertension.

  The American journal of cardiology 20010315

• Angiotensin converting enzyme (ACE) and non-ACE dependent angiotensin II generation in resistance arteries from patients with heart failure and coronary heart disease.

  Journal of the American College of Cardiology 20010315

• The role of angiotensin receptor blockers in the management of chronic heart failure.

  Archives of internal medicine 20010312

• Losartan reduces hematocrit in patients with chronic obstructive pulmonary disease and secondary erythrocytosis.

  Annals of internal medicine 20010306

• Glucocorticoid modulation of cardiovascular and autonomic function in preterm lambs: role of ANG II.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010301

• Cerebral Na concentration, Na appetite and thirst of sheep: influence of somatostatin and losartan.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010301

• Effect of oral contraceptives on the renin angiotensin system and renal function.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010301

• AT(1) receptor blockers prevent sympathetic hyperactivity and hypertension by chronic ouabain and hypertonic saline.

  American journal of physiology. Heart and circulatory physiology 20010301

• Identification, distribution, and expression of angiotensin II receptors in the normal human prostate and benign prostatic hyperplasia.

  Endocrinology 20010301

• MK-954 (losartan potassium) exerts endothelial protective effects against reperfusion injury: evidence of an e-NOS mRNA overexpression after global ischemia.

  Atherosclerosis 20010301

• Effect of losartan on degree of mitral regurgitation quantified by echocardiography.

  The American journal of cardiology 20010301

• Are angiotensin II receptor blockers more efficacious than placebo in heart failure? Implications of ELITE-2. Evaluation of Losartan In The Elderly.

  The American journal of cardiology 20010301

• Effect of angiotensin II on venodilator response to nitroglycerin.

  Clinical pharmacology and therapeutics 20010301

• Restoration of normal ventricular electrophysiology in renovascular hypertensive rabbits after treatment with losartan.

  Journal of cardiovascular pharmacology 20010301

• Mannitol-induced toxicity in a diabetic patient receiving losartan.

  The American journal of medicine 20010301

• Can angiotensin II receptor blockers be used in patients who have developed a cough or angioedema as a result of taking an ACE inhibitor?

  Cleveland Clinic journal of medicine 20010301

• [Pleasant added effect. Losartan improves sex in hypertension].

  MMW Fortschritte der Medizin 20010301

• [When hypertension damages microcirculation. A-II-antagonist corrects damage, beta blocker does not].

  MMW Fortschritte der Medizin 20010301

• Inhibition of angiotensin II-induced facilitation of sympathetic neurotransmission in the pithed rat: a comparison between losartan, irbesartan, telmisartan, and captopril.

  Journal of hypertension 20010301

• Anti-proteinuric effect of angiotension II receptor antagonist losartan in cases with glomerular lesions.

  Clinical nephrology 20010301

• A randomised, placebo-controlled, double-blind, crossover study of losartan and enalapril in patients with essential hypertension.

  Journal of human hypertension 20010301

• Antihypertensive effects of losartan and candesartan.

  Clinical therapeutics 20010301

• The influence of chronic antihypertensive treatment on the central pressor response in SHR.

  Hypertension research : official journal of the Japanese Society of Hypertension 20010301

• The release of the substrate for xanthine oxidase in hypertensive patients was suppressed by angiotensin converting enzyme inhibitors and alpha1-blockers.

  Journal of hypertension 20010301

• A novel effect of angiotensin on renal sympathetic nerve activity in mice.

  Journal of hypertension 20010301

• A comprehensive account on the role of efflux transporters in the gastrointestinal absorption of 13 commonly used substrate drugs in humans.

  International journal of clinical pharmacology and therapeutics 20010301

• Acute administration of nicotine impairs the hypotensive responses to bradykinin in rats.

  European journal of pharmacology 20010216

• Angiotensin II blockade reverses myocardial fibrosis in a transgenic mouse model of human hypertrophic cardiomyopathy.

  Circulation 20010213

• Comparative effect of ace inhibition and angiotensin II type 1 receptor antagonism on bioavailability of nitric oxide in patients with coronary artery disease: role of superoxide dismutase.

  Circulation 20010213

• Angiotensin II type 1 receptor blockers.

  Circulation 20010213

• [Treating not only blood pressure. Advantages for microcirculation].

  MMW Fortschritte der Medizin 20010208

• [Well tolerated sartans. More normal blood pressure finally?].

  MMW Fortschritte der Medizin 20010208

• Pressure overload increases GATA4 binding activity via endothelin-1.

  Circulation 20010206

• Losartan and fetal toxic effects.

  Lancet (London, England) 20010203

• Hyperoxia/normoxia-driven retinal angiogenesis in mice: a role for angiotensin II.

  Investigative ophthalmology & visual science 20010201

• Angiotensin II is involved in nitric oxide synthase and cyclo-oxygenase inhibition-induced leukocyte-endothelial cell interactions in vivo.

  British journal of pharmacology 20010201

• Gap junction remodeling in hypertrophied left ventricles of aortic-banded rats: prevention by angiotensin II type 1 receptor blockade.

  Journal of molecular and cellular cardiology 20010201

• Different effects of angiotensin II and catecholamine on renal cell apoptosis and proliferation in rats.

  Kidney international 20010201

• DNA damage of lymphocytes in experimental chronic renal failure: beneficial effects of losartan.

  Kidney international. Supplement 20010201

• A two-state receptor model for the interaction between angiotensin II type 1 receptors and non-peptide antagonists.

  Biochemical pharmacology 20010201

• Combined therapy with an angiotensin II receptor blocker and an angiotensin-converting enzyme inhibitor in heart failure.

  The Annals of pharmacotherapy 20010201

• Modulation of alveolar-capillary sodium handling as a mechanism of protection of gas transfer by enalapril, and not by losartan, in chronic heart failure.

  Journal of the American College of Cardiology 20010201

• Role of angiotensin II in altered baroreflex function of conscious rabbits during late pregnancy.

  American journal of obstetrics and gynecology 20010201

• Mortality after coronary artery occlusion in different models of cardiac hypertrophy in rats.

  Hypertension (Dallas, Tex. : 1979) 20010201

• Angiotensin II relaxes microvessels via the AT(2) receptor and Ca(2+)-activated K(+) (BK(Ca)) channels.

  Hypertension (Dallas, Tex. : 1979) 20010201

• Role of endothelin and isoprostanes in slow pressor responses to angiotensin II.

  Hypertension (Dallas, Tex. : 1979) 20010201

• Angiotensin II induces migration and Pyk2/paxillin phosphorylation of human monocytes.

  Hypertension (Dallas, Tex. : 1979) 20010201

• Expression of cell cycle proteins in blood vessels of angiotensin II-infused rats: role of AT(1) receptors.

  Hypertension (Dallas, Tex. : 1979) 20010201

• Angiotensin II increases vesicular trafficking in brain neurons.

  Hypertension (Dallas, Tex. : 1979) 20010201

• CoenzymeA glutathione disulfide is a potent modulator of angiotensin II-induced vasoconstriction.

  American journal of hypertension 20010201

• Left ventricular hypertrophy and angiotensin II antagonists.

  American journal of hypertension 20010201

• Analysis of binary mixtures of losartan potassium and hydrochlorothiazide by using high performance liquid chromatography, ratio derivative spectrophotometric and compensation technique.

  Journal of pharmaceutical and biomedical analysis 20010201

• Interactions of ligands at angiotensin II-receptors and imidazoline receptors.

  Japanese journal of pharmacology 20010201

• Angiogenesis induced by electrical stimulation is mediated by angiotensin II and VEGF.

  Microcirculation (New York, N.Y. : 1994) 20010201

• Management of hypertension and heart failure with AT1 receptor blockade.

  JPMA. The Journal of the Pakistan Medical Association 20010201

• The role of angiotensin II, endothelin-1 and transforming growth factor-beta as autocrine/paracrine mediators of stretch-induced cardiomyocyte hypertrophy.

  Molecular and cellular biochemistry 20010201

• Comparative studies on the memory-enhancing actions of captopril and losartan in mice using inhibitory shock avoidance paradigm.

  Neuropeptides 20010201

• Regulation of K+ transport in the rat distal colon via angiotensin II subtype receptors and K+ -pathways.

  Acta physiologica Scandinavica 20010201

• Central AT1 and AT2 receptors mediate chronic intracerebroventricular angiotensin II-induced drinking in rats fed high sodium chloride diet from weaning.

  Acta physiologica Scandinavica 20010201

• A kinetic model for the metabolic interaction of two substrates at the active site of cytochrome P450 3A4.

  The Journal of biological chemistry 20010119

• Central interactions between angiotensin II and PGD(2) in the regulation of vasopressin and oxytocin secretion in dehydrated rats.

  Brain research 20010119

• Left ventricular hypertrophy with exercise and ACE gene insertion/deletion polymorphism: a randomized controlled trial with losartan.

  Circulation 20010116

• Angiotensin II inhibits rat arterial KATP channels by inhibiting steady-state protein kinase A activity and activating protein kinase Ce.

  The Journal of physiology 20010115

• Mitogen-activated protein kinase activity regulation role of angiotensin and endothelin systems in vascular smooth muscle cells.

  European journal of pharmacology 20010105

• Intrarenal renin-angiotensin system contributes to tubular acidification adaptation following uninephrectomy.

  Experimental nephrology 20010101

• Losartan, an angiotensin type I receptor antagonist, improves conduit vessel endothelial function in Type II diabetes.

  Clinical science (London, England : 1979) 20010101

• Cysteinyl leukotrienes are involved in angiotensin II-induced contraction of aorta from spontaneously hypertensive rats.

  Cardiovascular research 20010101

• ANG II potentiates mitogenic effect of norepinephrine in vascular muscle cells: role of FGF-2.

  American journal of physiology. Heart and circulatory physiology 20010101

• Increased AT(1) receptor expression and mRNA in kidney glomeruli of AT(2) receptor gene-disrupted mice.

  American journal of physiology. Renal physiology 20010101

• Angiotensin signaling and receptor types in teleost fish.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20010101

• Effect of electrocardiographic left ventricular hypertrophy on left ventricular systolic function in systemic hypertension (The LIFE Study). Losartan Intervention For Endpoint.

  The American journal of cardiology 20010101

• Effect of renin-angiotensin system blockade on the expression of the angiotensinogen gene and induction of hypertrophy in rat kidney proximal tubular cells.

  Experimental nephrology 20010101

• Antihypertensive monotherapy and cardiovascular responses to an acoustic startle stimulus.

  Journal of cardiovascular pharmacology 20010101

• Interaction between paracrine tumor necrosis factor-alpha and paracrine angiotensin II during myocardial ischemia.

  Journal of the American College of Cardiology 20010101

• Renal and vascular injury induced by exogenous angiotensin II is AT1 receptor-dependent.

  Nephron 20010101

• New competition in the realm of renin-angiotensin axis inhibition; the angiotensin II receptor antagonists in congestive heart failure.

  The Annals of pharmacotherapy 20010101

• Relation of left ventricular geometry and function to systemic hemodynamics in hypertension: the LIFE Study. Losartan Intervention For Endpoint Reduction in Hypertension Study.

  Journal of hypertension 20010101

• Losartan versus enalapril on cerebral edema and proteinuria in stroke-prone hypertensive rats.

  American journal of hypertension 20010101

• Functional expression of angiotensin II receptors in type-I cells of the rat carotid body.

  Pflugers Archiv : European journal of physiology 20010101

• Contribution of angiotensin II, endothelin 1 and the endothelium to the slow inotropic response to stretch in ferret papillary muscle.

  Pflugers Archiv : European journal of physiology 20010101

• Role of the central nervous system in the development of hypertension produced by chronic nitric oxide blockade in rats.

  Hypertension research : official journal of the Japanese Society of Hypertension 20010101

• Acute effects of E-3174, a human active metabolite of losartan, on the cardiovascular system in tachycardia-induced canine heart failure.

  Hypertension research : official journal of the Japanese Society of Hypertension 20010101

• What is the optimal medical management of ischemic heart failure?

  Progress in cardiovascular diseases 20010101

• Repeated transient anuria following losartan administration in a patient with a solitary kidney.

  Renal failure 20010101

• Modulation of the renin-angiotensin system may alter the adrenocortical regeneration.

  Cytobios 20010101

• Uricosuric effect of losartan in renal transplanted patients.

  Transplantation proceedings 20010101

• Angiotensin II receptor blockade: a novel strategy to prevent immunosuppressant-associated cancer progression.

  Transplantation proceedings 20010101

• The effect of losartan on posttransplant erythrocytosis.

  Transplantation proceedings 20010101

• Sixth international workshop on scleroderma research, Oxford, UK, 30 July--22 August 2000.

  Arthritis research 20010101

• Renoprotective effect of angiotensin II receptor antagonists in experimental chronic renal failure.

  American journal of nephrology 20010101

• Fos protein is required for the re-expression of angiotensin II type 1 receptors in the nucleus tractus solitarii after baroreceptor activation in the rat.

  Neuroscience 20010101

• Baroreflex inhibition of cardiac sympathetic outflow is attenuated by angiotensin II in the nucleus of the solitary tract.

  Neuroscience 20010101

• The comparative pharmacology of angiotensin II receptor antagonists.

  Blood pressure. Supplement 20010101

• [Evaluation of the evenness of the antihypertensive effect of losartan and captopril by using a 24-hour monitoring of arterial pressure].

  Terapevticheskii arkhiv 20010101

• Effects of losartan, prazosin and a vasopressin V1-receptor antagonist on renal and femoral blood flow in conscious sheep.

  Acta physiologica Scandinavica 20010101

• Clinical pharmacokinetics of fluvastatin.

  Clinical pharmacokinetics 20010101

• Angiotensin II activates nuclear transcription factor-kappaB in aorta of normal rats and in vascular smooth muscle cells of AT1 knockout mice.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101

• Angiotensin II AT(1) receptor antagonists and platelet activation.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101

• Effect of angiotensin II receptor blockade on renal disease progression in patients with non-diabetic chronic renal failure.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101

• Losartan reduces microalbuminuria in hypertensive microalbuminuric type 2 diabetics.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101

• Effect of losartan on TGF-beta1 and urinary albumin excretion in patients with type 2 diabetes mellitus and microalbuminuria.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101

• Role of transforming growth factor-beta1 in the progression of chronic allograft nephropathy.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101

• Angiotensin II type 1 (AT1) receptor antagonists in the treatment of hypertension after renal transplantation.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101

• [A possible adverse effect from the association of losartan-mefenamic acid in hemodialysis].

  Nephrologie 20010101

• Reversible renal impairment induced by treatment with the angiotensin II receptor antagonist candesartan in a patient with bilateral renal artery stenosis.

  BMC nephrology 20010101

• Chronic effects of ACE-inhibition (quinapril) and angiotensin-II-type-1 receptor blockade (losartan) on atrial natriuretic peptide in brain nuclei of rats with experimental myocardial infarction.

  Basic research in cardiology 20010101

• Antihypertensive efficacy of candesartan in comparison to losartan: the CLAIM study.

  Journal of clinical hypertension (Greenwich, Conn.) 20010101

• Strain differences in the anxiolytic effects of losartan in the mouse.

  Pharmacology, biochemistry, and behavior 20010101

• Effects of gestation on ovine fetal and maternal angiotensin receptor subtypes in the heart and major blood vessels.

  Experimental physiology 20010101

• A prospective comparison of four antihypertensive agents in daily clinical practice.

  Journal of clinical hypertension (Greenwich, Conn.) 20010101

• [Severe hypoglycemia secondary to angiotensin-converting-enzyme inhibitors in the absence of diabetes mellitus. Report of a case].

  Gaceta medica de Mexico 20010101

• Studies on the antithrombotic action of AT1 receptor antagonists.

  Medical science monitor : international medical journal of experimental and clinical research 20010101

• Effects of angiotensin II and the AT(1) receptor antagonist losartan on the renal excretion of urodilatin.

  Kidney & blood pressure research 20010101

• [Therapeutic perspectives: association of ACE inhibitors and angiotensin receptor blockers].

  La Clinica terapeutica 20010101

• [Angiotensin receptor blockers--significance for the therapy of hypertension].

  Wiener medizinische Wochenschrift (1946) 20010101

• [Angiotensin I receptor blockers for heart failure].

  Wiener medizinische Wochenschrift (1946) 20010101

• [Angiotensin II type-1-receptor antagonists from the viewpoint of nephrology].

  Wiener medizinische Wochenschrift (1946) 20010101

• [Angiotensin II type-1 receptor antagonists and diabetes mellitus].

  Wiener medizinische Wochenschrift (1946) 20010101

• Perindopril/indapamide 2/0.625 mg/day: a review of its place in the management of hypertension.

  Drugs 20010101

• Pharmacological differences among angiotensin II receptor antagonists.

  Blood pressure. Supplement 20010101

• Clinical differences among angiotensin II receptor antagonists.

  Blood pressure. Supplement 20010101

• LIFE study--still-blinded results show promise.

  Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20010101

• Angiotensin-induced enhancement of excitatory junction potentials evoked by periarteriolar nerve stimulation and vasoconstriction in rat mesenteric arteries are both mediated by the angiotensin AT1 receptor.

  Pharmacology 20010101

• New stuff about the diabetic kidney.

  Journal of clinical hypertension (Greenwich, Conn.) 20010101

• [Can Sartane help a failing heart? AT1-receptor antagonists in cardiac insufficiency].

  Pharmazie in unserer Zeit 20010101

• Prescribing patterns and cost of antihypertensive drugs in an internal medicine clinic.

  Indian heart journal 20010101

• [Use of isosorbide dinitrate and antagonists of angiotensin II in patients with stable angina pectoris in early stages of cardiac insufficiency].

  Likars'ka sprava 20010101

• [Effects of inhibitors of angiotensin-converting enzyme combined with antagonists of angiotensin II receptors on endothelial function in patients with chronic cardiac insufficiency].

  Likars'ka sprava 20010101

• [Effects of the long-term treatment with losartan and captopril and of the abrupt cessation on circadian blood pressure profile].

  Eksperimental'naia i klinicheskaia farmakologiia 20010101

• Solution-phase synthesis of an aminomethyl-substituted biaryl library via sequential amine N-alkylation and Suzuki cross-coupling.

  Journal of combinatorial chemistry 20010101

• Impact of antihypertensive therapy on the skeleton: effects of enalapril and AT1 receptor antagonist losartan in female rats.

  Physiological research 20010101

• Telmisartan: a review of its use in hypertension.

  Drugs 20010101

• [Effect of angiotensin II and alpha2 adrenergic receptor antagonists on angiotensin II-stimulated nitric oxide release].

  Medicina 20010101

• Comparative efficacy of olmesartan, losartan, valsartan, and irbesartan in the control of essential hypertension.

  Journal of clinical hypertension (Greenwich, Conn.) 20010101

• Reporting of adverse drug reactions in randomised controlled trials - a systematic survey.

  BMC clinical pharmacology 20010101

• Clinical comparative trials of angiotensin II type 1 (AT1)-receptor blockers.

  Blood pressure. Supplement 20010101

• Importance of smooth and sustained blood pressure control in preventing cardiovascular morbidity and mortality.

  Blood pressure. Supplement 20010101

• The relationship between dose and antihypertensive effect for different AT1-receptor blockers.

  Blood pressure. Supplement 20010101

• Pharmacology of AT1-receptor blockers.

  Blood pressure. Supplement 20010101

• The heterotopic tracheal allograft as an animal model of obliterative bronchiolitis.

  Respiratory research 20010101

• Vascular protection: current possibilities and future perspectives.

  International journal of clinical practice. Supplement 20010101

• Is losartan as effective as enalapril on posttransplant persistent proteinuria?

  Transplantation proceedings 20010101

• Assessment of new cardiovascular drugs. Relationships between considerations, professional characteristics, and prescribing.

  International journal of technology assessment in health care 20010101

• Simultaneous determination of losartan and hydrochlorothiazide in combined dosage forms by first-derivative spectroscopy and high-performance thin-layer chromatography.

  Journal of AOAC International 20010101

• Interactions of the renin-angiotensin system and alpha-1 adrenoceptors on renal hemodynamics in healthy and acute renal failure rats: the role of nitric oxide.

  Blood pressure 20010101

• Angiotensin-converting enzyme inhibitors as inducers of adverse cutaneous reactions.

  Acta dermato-venereologica 20010101

• Effects of long-term enalapril and losartan therapy of hypertension on cardiovascular aldosterone.

  Hormone research 20010101

• [Effect of blocking angiotensin receptors on cerebral blood flow in the post-ischemic period in hypertensive rats].

  Patologicheskaia fiziologiia i eksperimental'naia terapiia 20010101

• How can the differences among AT1-receptor antagonists be explained?

  Cell biochemistry and biophysics 20010101

• A study on the efficacy and safety of losartan in elderly patients with mild to moderate essential hypertension.

  International urology and nephrology 20010101

• Effect of losartan treatment on the proteinuria in normotensive patients having proteinuria due to secondary amyloidosis.

  Upsala journal of medical sciences 20010101

• Effects of vasoactive substances released from ischemic reperfused liver on the isolated rat heart.

  Experimental and clinical cardiology 20010101

• Effects of losartan on ventricular remodeling in experimental infarction in rats.

  Arquivos brasileiros de cardiologia 20001201

• Angiotensin II binding and extracellular matrix remodelling in a rat model of myocardial infarction.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20001201

• Deoxycorticosterone suppresses the effects of losartan in nitric oxide-deficient hypertensive rats.

  Journal of the American Society of Nephrology : JASN 20001101

• Long-term central hemodynamic effects at rest and during exercise of losartan in essential hypertension.

  American heart journal 20001001

• First dose hypotension after angiotensin converting enzyme inhibitor captopril and angiotensin II blocker losartan in patients with acute myocardial infarction.

  International journal of cardiology 20000915

• Effect of indomethacin on blood pressure lowering by captopril and losartan in hypertensive patients.

  Hypertension (Dallas, Tex. : 1979) 20000901

• [Acute kidney failure and losartan: a recently observed event of antagonists of angiotensin II AT1 receptors].

  Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20000901

• The involvement of AT(2)-receptor in the antithrombotic effect of losartan in renal hypertensive rats.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20000901

• The antithrombotic effect of angiotensin-(1-7) closely resembles that of losartan.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20000901

• Modulation of apoptotic and inflammatory genes by bioflavonoids and angiotensin II inhibition in ureteral obstruction.

  Urology 20000801

• Acute and chronic angiotensin-1 receptor antagonism reverses endothelial dysfunction in atherosclerosis.

  Circulation 20000523

• Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial--the Losartan Heart Failure Survival Study ELITE II.

  Lancet (London, England) 20000506

• Lack of evidence of blood pressure-independent protection by renin-angiotensin system blockade after renal ablation.

  Kidney international 20000401

• Losartan: a review of its use, with special focus on elderly patients.

  Drugs & aging 20000301

• Losartan-induced apoptosis as a novel mechanism for the prevention of vascular lesion formation after injury.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20000301

• Protease inhibitors: current status and future prospects.

  Journal of medicinal chemistry 20000210

• Neuropeptide Y enhances potassium excretion by mechanisms distinct from those controlling sodium excretion.

  Canadian journal of physiology and pharmacology 20000201

• Meta-analysis of observed mortality data from all-controlled, double-blind, multiple-dose studies of losartan in heart failure. Losartan Heart Failure Mortality Meta-analysis Study Group.

  The American journal of cardiology 20000115

• Arterial responses in vitro and plasma digoxin immunoreactivity after losartan and enalapril treatments in experimental hypertension.

  Pharmacology & toxicology 20000101

• [Cerebrovascular circulation during blockade of angiotensin receptors].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20000101

• Angiotensin II receptor blockade unmasks a depressor response to endothelin antagonists in rats.

  Fundamental & clinical pharmacology 20000101

• Use of ambulatory blood pressure monitoring to evaluate the selective angiotensin II receptor antagonist, telmisartan, and other antihypertensive drugs.

  Blood pressure monitoring 20000101

• [Prospects of endothelial dysfunction reversion in patients with congestive heart failure].

  Klinicheskaia meditsina 20000101

• Randomised comparison of losartan vs. captopril on quality of life in elderly patients with symptomatic heart failure: the losartan heart failure ELITE quality of life substudy.

  Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20000101

• Study on the effects of losartan on cardiomyocyte apoptosis and gene expression after ischemia and reperfusion in vivo in rats.

  Journal of Tongji Medical University = Tong ji yi ke da xue xue bao 20000101

• Anaemia due to ACE inhibitors and losartan in patients with renal failure.

  Prescrire international 19991201

• Angiotensin II stimulates intercellular adhesion molecule-1 (ICAM-1) expression by human vascular endothelial cells and increases soluble ICAM-1 release in vivo.

  Circulation 19991012

• EXP3174, the AII antagonist human metabolite of losartan, but not losartan nor the angiotensin-converting enzyme inhibitor captopril, prevents the development of lethal ischemic ventricular arrhythmias in a canine model of recent myocardial infarction.

  Journal of the American College of Cardiology 19990901

• Losartan-induced angioedema.

  The Annals of pharmacotherapy 19990901

• Angioedema due to losartan.

  The Annals of pharmacotherapy 19990901

• Comparative study of TA-606, a novel angiotensin II receptor antagonist, with losartan in terms of species difference and orthostatic hypotension.

  Japanese journal of pharmacology 19990901

• 2-Tetradecylglycidic acid, an inhibitor of carnitine palmitoyltransferase-1, induces myocardial hypertrophy via the AT1 receptor.

  Journal of molecular and cellular cardiology 19990801

• Losartan: a study of pharmacovigilance data on 14,522 patients.

  Journal of human hypertension 19990801

• Modulation of extracellular superoxide dismutase expression by angiotensin II and hypertension.

  Circulation research 19990709

• Brain renin-angiotensin system and ouabain-induced sympathetic hyperactivity and hypertension in Wistar rats.

  Hypertension (Dallas, Tex. : 1979) 19990701

• Effects of losartan versus captopril on mortality in patients with symptomatic heart failure: rationale, design, and baseline characteristics of patients in the Losartan Heart Failure Survival Study--ELITE II.

  Journal of cardiac failure 19990601

• Arterial function in nitric oxide-deficient hypertension: influence of long-term angiotensin II receptor antagonism.

  Cardiovascular research 19990601

• The effects of fluvastatin, a CYP2C9 inhibitor, on losartan pharmacokinetics in healthy volunteers.

  Journal of clinical pharmacology 19990401

• A comparison of the angiotensin II antagonists valsartan and losartan in the treatment of essential hypertension.

  American journal of hypertension 19990401

• Angiotensin II receptor blockade in normotensive subjects: A direct comparison of three AT1 receptor antagonists.

  Hypertension (Dallas, Tex. : 1979) 19990301

• Binding of the antagonist [3H]candesartan to angiotensin II AT1 receptor-transfected [correction of tranfected] Chinese hamster ovary cells.

  European journal of pharmacology 19990219

• Hemodynamic and renal effects of indomethacin in losartan-treated hypertensive individuals.

  American journal of hypertension 19990201

• Angioedema due to losartan.

  Allergy 19990101

• The cost-effectiveness of losartan versus captopril in patients with symptomatic heart failure.

  Cardiology 19990101

• Effects of beta-receptor blockade and angiotensin II type I receptor antagonism in isoproterenol-induced heart failure in the rat.

  Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 19990101

• Increased efficacy and tolerability with losartan plus hydrochlorothiazide in patients with uncontrolled hypertension and therapy-related symptoms receiving two monotherapies.

  Advances in therapy 19990101

• Prediction of aryl hydrocarbon receptor-mediated enzyme induction of drugs and chemicals by mRNA quantification.

  Chemical research in toxicology 19981201

• Dissociation of blood pressure reduction from end-organ damage in TGR(mREN2)27 transgenic hypertensive rats.

  Journal of hypertension 19981201

• Hepatic injury associated with losartan.

  The Annals of pharmacotherapy 19981201

• Losartan: a selective angiotensin II type 1 (AT1) receptor antagonist for the treatment of heart failure.

  Expert opinion on investigational drugs 19981101

• Angioneurotic edema attributed to the use of losartan.

  Archives of internal medicine 19981012

• Interaction of mRNAs for angiotensin II type 1 and type 2 receptors to vascular remodeling in spontaneously hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 19980901

• Aphtous ulcers of the mouth associated with losartan.

  Clinical nephrology 19980901

• Angiotensin receptor blockade blunts hyperinsulinemia-induced hypertension in rats.

  Hypertension (Dallas, Tex. : 1979) 19980801

• Effects of losartan and enalapril on small artery structure in hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 19980801

• Anaemia in dialysis patients as a side-effect of sartanes.

  Lancet (London, England) 19980725

• Reversible dysgeusia attributed to losartan.

  Annals of internal medicine 19980701

• Regulation of glomerular TGF-beta expression in the contralateral kidney of two-kidney, one-clip hypertensive rats.

  Journal of the American Society of Nephrology : JASN 19980501

• Chronic treatment with losartan ameliorates vascular dysfunction induced by aging in spontaneously hypertensive rats.

  Journal of hypertension 19980501

• Effects of AT1 receptor blockade on blood pressure and the renin-angiotensin system in spontaneously hypertensive rats of the stroke prone strain.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 19980201

• Participation of AT1 and AT2 receptor subtypes in the tonic inhibitory modulation of baroreceptor reflex response by endogenous angiotensins at the nucleus tractus solitarii in the rat.

  Brain research 19980126

• Interaction of the renin-angiotensin system and the endothelin system in cardiac hypertrophy.

  Journal of cardiovascular pharmacology 19980101

• Role of sympathetic nerves for the stimulation of the renin system by angiotensin II receptor blockade.

  Journal of hypertension 19971201

• Interaction of angiotensin II and TGF-beta 1 in the rat remnant kidney.

  Journal of the American Society of Nephrology : JASN 19971101

• Molecular mechanism of angiotensin II type I and type II receptors in cardiac hypertrophy of spontaneously hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 19971001

• Effects of renin-angiotensin blockade on sympathetic reactivity and beta-adrenergic pathway in the spontaneously hypertensive rat.

  Hypertension (Dallas, Tex. : 1979) 19970801

• The angiotensin-II receptor antagonist, losartan, inhibits LDL lipid peroxidation and atherosclerosis in apolipoprotein E-deficient mice.

  Biochemical and biophysical research communications 19970730

• Endothelial dysfunction in spontaneously hypertensive rats: consequences of chronic treatment with losartan or captopril.

  Journal of hypertension 19970601

• Involvement of AT2 receptors at NRVL in tonic baroreflex suppression by endogenous angiotensins.

  The American journal of physiology 19970501

• The effect of Losartan, an angiotensin II antagonist, on cardiac function, mass and morphology in rats after repeated hyperbaric exposures.

  Scandinavian journal of clinical and laboratory investigation 19970501

• Deterioration in renal function with enalapril but not losartan in a patient with renal artery stenosis in a solitary kidney.

  Heart (British Cardiac Society) 19970401

• AT1 receptor blockade and the sympathoadrenal response to insulin-induced hypoglycemia in humans.

  The American journal of physiology 19970301

• Reversible acute renal failure induced by losartan in a renal transplant recipient.

  Postgraduate medical journal 19970201

• Role of central ANG II receptors in stress-induced cardiovascular and hyperthermic responses in rats.

  The American journal of physiology 19970101

• Smooth muscle apoptosis during vascular regression in spontaneously hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 19970101

• Haemodynamic and endocrine effects of type 1 angiotensin II receptor blockade in patients with hypoxaemic cor pulmonale.

  Cardiovascular research 19970101

• Losartan reduces albuminuria in patients with essential hypertension. An enalapril controlled 3 months study.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19970101

• Lithium intoxication in an elderly patient after combined treatment with losartan.

  European journal of clinical pharmacology 19970101

• Clinical safety and tolerability of losartan.

  Clinical therapeutics 19970101

• Acute effects of angiotensin II receptor antagonist on autoregulation of zonal glomerular filtration rate in renovascular hypertensive rats.

  Kidney & blood pressure research 19970101

• Losartan blocks aldosterone and renal vascular responses to angiotensin II in humans.

  Hypertension (Dallas, Tex. : 1979) 19961201

• Effects of losartan on cerebral arteries in stroke-prone spontaneously hypertensive rats.

  Journal of hypertension 19961101

• Brief report: acute renal failure after losartan treatment in a patient with bilateral renal artery stenosis.

  Blood pressure 19961101

• Comparative cardiovascular effects of the angiotensin II type 1 receptor antagonists ZD 7155 and losartan in the rat.

  The Journal of pharmacy and pharmacology 19960801

• Losartan-induced azotemia in a diabetic recipient of a kidney transplant.

  The New England journal of medicine 19960509

• Losartan potassium: a review of its pharmacology, clinical efficacy and tolerability in the management of hypertension.

  Drugs 19960501

• Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.

  Journal of medicinal chemistry 19960202

• Controlled trial of losartan given concomitantly with different doses of hydrochlorothiazide in hypertensive patients.

  Blood pressure 19960101

• Effect of losartan on right ventricular hypertrophy and cardiac angiotensin I-converting enzyme activity in pulmonary hypertensive rats.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 19960101

• The potential role of nitric oxide in angiotensin II-receptor blockade.

  Blood pressure. Supplement 19960101

• Global efficacy and tolerability of losartan, an angiotensin II subtype 1-receptor antagonist, in the treatment of hypertension.

  Blood pressure. Supplement 19960101

• Losartan: first of a new class of angiotensin antagonists for the management of hypertension.

  Journal of clinical pharmacology 19960101

• The angiotensin II type 1 receptor blocker losartan in clinical practice: a review.

  Clinical therapeutics 19960101

• Chronic angiotensin II antagonism with losartan in one-kidney, one clip hypertensive rats: effect on cardiac hypertrophy, urinary sodium and water excretion and the natriuretic system.

  Journal of hypertension 19960101

• Angioedema induced by the angiotensin II blocker losartan.

  The New England journal of medicine 19951207

• Effects of losartan on blood pressure, metabolic alterations, and vascular reactivity in the fructose-induced hypertensive rat.

  Hypertension (Dallas, Tex. : 1979) 19951201

• The effects of angiotensin II receptor blockade with losartan on systemic blood pressure and renal and extrarenal prostaglandin synthesis in women with essential hypertension.

  American journal of hypertension 19951201

• Binding of valsartan to mammalian angiotensin AT1 receptors.

  Regulatory peptides 19951110

• Discovery of losartan, the first angiotensin II receptor antagonist.

  Journal of human hypertension 19951101

• Effects of losartan on insulin sensitivity in severe hypertension: connections through sympathetic nervous system activity?

  Journal of human hypertension 19951101

• Nitric oxide and prostaglandins in the prolonged effects of losartan and ramipril in hypertension.

  Hypertension (Dallas, Tex. : 1979) 19950801

• Comparative effects of losartan, captopril, and enalapril on murine acute myocarditis due to encephalomyocarditis virus.

  Journal of cardiovascular pharmacology 19950701

• The preclinical basis of the therapeutic evaluation of losartan.

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19950701

• Antihypertensive efficacy and tolerability of once daily losartan potassium compared with captopril in patients with mild to moderate essential hypertension.

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19950701

• Safety and tolerability of losartan compared with atenolol, felodipine and angiotensin converting enzyme inhibitors.

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19950701

• Effects of chronic NO synthase inhibition in rats on renin-angiotensin system and sympathetic nervous system.

  The American journal of physiology 19950601

• Safety and tolerability of losartan potassium, an angiotensin II receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipine ER, and angiotensin-converting enzyme inhibitors for the treatment of systemic hypertension.

  The American journal of cardiology 19950415

• Pharmacology of LR-B/081, a new highly potent, selective and orally active, nonpeptide angiotensin II AT1 receptor antagonist.

  British journal of pharmacology 19950301

• Antihypertensive and renal-protective effects of losartan in streptozotocin diabetic rats.

  Journal of hypertension 19950101

• Angiotensin II maintains, but does not mediate, isoproterenol-induced cardiac hypertrophy in rats.

  The American journal of physiology 19941001

• Cardiovascular hypertrophy in one-kidney, one clip renal hypertensive rats: a role for angiotensin II?

  Journal of hypertension 19941001

• Hemodynamic and neurohumoral effects of the angiotensin II antagonist losartan in patients with heart failure.

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19940701

• Angiotensin II and alpha 1-adrenergic tone in chronic nitric oxide blockade-induced hypertension.

  The American journal of physiology 19940501

• Is the antiproteinuric effect of ACE inhibition mediated by interference in the renin-angiotensin system?

  Kidney international 19940301

• Human angiotensin receptor subtypes.

  Current opinion in nephrology and hypertension 19940101

• Pressor mechanisms in adriamycin-induced nephropathy with hypertension in rats.

  Hypertension (Dallas, Tex. : 1979) 19940101

• Renin-angiotensin system and minoxidil-induced cardiac hypertrophy in rats.

  The American journal of physiology 19931101

• Angiotensin II antagonists.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 19931101

• Characterization of [3H]losartan receptors in isolated rat glomeruli.

  European journal of pharmacology 19931015

• Pharmacological profile of valsartan: a potent, orally active, nonpeptide antagonist of the angiotensin II AT1-receptor subtype.

  British journal of pharmacology 19931001

• Hemodynamic and neurohormonal effects of the angiotensin II antagonist losartan in patients with congestive heart failure.

  Circulation 19931001

• Pharmacological characterization of the novel nonpeptide angiotensin II receptor antagonist, BIBR 277.

  British journal of pharmacology 19930901

• Short- and long-term effect of angiotensin II receptor blockade in rats with experimental diabetes.

  Journal of the American Society of Nephrology : JASN 19930701

• Angiotensin II receptors and angiotensin II receptor antagonists.

  Pharmacological reviews 19930601

• Sodium and angiotensin in hypertension induced by long-term nitric oxide blockade.

  Hypertension (Dallas, Tex. : 1979) 19930601

• Dup 753 prevents the development of puromycin aminonucleoside-induced nephrosis.

  European journal of pharmacology 19930519

• How well have animal studies with losartan predicted responses in humans?

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19930401

• Regulated expression of angiotensin II (AT2) binding sites in R3T3 cells.

  Regulatory peptides 19930319

• Control of blood pressure and end-organ damage in maturing salt-loaded stroke-prone spontaneously hypertensive rats by oral angiotensin II receptor blockade.

  Journal of hypertension 19930101

• Hormonal and cardiovascular effects of losartan (DuP753), an angiotensin receptor antagonist, in nonhuman primates.

  The Journal of pharmacology and experimental therapeutics 19930101

• Characterization of the binding of [3H]L-158,809: a new potent and selective nonpeptide angiotensin II receptor (AT1) antagonist radioligand.

  Molecular pharmacology 19921201

• [125I]EXP985: a highly potent and specific nonpeptide radioligand antagonist for the AT1 angiotensin receptor.

  Biochemical and biophysical research communications 19921116

• Central DuP 753 does not lower blood pressure in spontaneously hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 19920601

• Angiotensin II receptor antagonist losartan has persistent effects on blood pressure in the young spontaneously hypertensive rat: lack of relation to vascular structure.

  Journal of vascular research 19920101

• Characterization of distinct angiotensin II binding sites in rat adrenal gland and bovine cerebellum using selective nonpeptide antagonists.

  Journal of cardiovascular pharmacology 19910201

• Subclasses of angiotensin II binding sites and their functional significance.

  Molecular pharmacology 19900901

• Hypotensive action of DuP 753, an angiotensin II antagonist, in spontaneously hypertensive rats. Nonpeptide angiotensin II receptor antagonists: X.

  Hypertension (Dallas, Tex. : 1979) 19900501

• Two distinct angiotensin II receptor binding sites in rat adrenal revealed by new selective nonpeptide ligands.

  Molecular pharmacology 19900301

• Preliminary biochemical characterization of two angiotensin II receptor subtypes.

  Biochemical and biophysical research communications 19890830