114873-10-8 | Boc-D-2-fluorophenylalanine

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$18.00	$13.00
5g	97%	in stock	$60.00	$42.00
25g	97%	in stock	$152.00	$106.00

Description

• Catalog Number: AA19736
• Chemical Name: Boc-D-2-fluorophenylalanine
• CAS Number: 114873-10-8
• Molecular Formula: C14H18FNO4
• Molecular Weight: 283.2954
• MDL Number: MFCD00672521
• SMILES: O=C(OC(C)(C)C)N[C@@H](C(=O)O)Cc1ccccc1F

Computed Properties

• Complexity: 354
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 6
• XLogP3: 2.6

Upstream Synthesis Route

Boc-D-Phe(2-F)-OH, also known as tert-butoxycarbonyl-D-phenylalanine(2-fluoro)-ol, is a crucial building block in chemical synthesis. This compound finds widespread application in peptide synthesis, particularly in the pharmaceutical industry. By incorporating Boc-D-Phe(2-F)-OH into peptide sequences, chemists are able to introduce the unique properties of phenylalanine and the fluorine substituent into the peptide structure.The Boc (tert-butoxycarbonyl) protecting group serves to shield the amine group of phenylalanine, providing selectivity in peptide bond formation. Additionally, the presence of the 2-fluoro substituent enhances the peptide's bioavailability and stability, making it a valuable tool in drug discovery and development.Overall, Boc-D-Phe(2-F)-OH plays a crucial role in enhancing the properties of peptides, enabling the fine-tuning of their biological activity and pharmacokinetic profile. Its versatile applications in chemical synthesis make it an indispensable component in the creation of novel peptide-based therapeutics and biochemical tools.