114873-13-1 | Boc-3,4-dichloro-d-phenylalanine

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$16.00	$11.00
1g	98%	in stock	$19.00	$14.00
5g	98%	in stock	$57.00	$40.00
25g	98%	in stock	$281.00	$197.00

Description

• Catalog Number: AA19733
• Chemical Name: Boc-3,4-dichloro-d-phenylalanine
• CAS Number: 114873-13-1
• Molecular Formula: C14H17Cl2NO4
• Molecular Weight: 334.1951
• MDL Number: MFCD00151887
• SMILES: O=C(OC(C)(C)C)N[C@@H](C(=O)O)Cc1ccc(c(c1)Cl)Cl

Computed Properties

• Complexity: 384
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 21
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 6
• XLogP3: 3.8

Upstream Synthesis Route

Boc-D-Phe(3,4-Cl2)-OH, a derivative of phenylalanine, plays a crucial role in chemical synthesis as a building block for creating peptide and peptidomimetic compounds. This compound, with its specific chemical structure incorporating a Boc (tert-butoxycarbonyl) protecting group, a chlorine substituent at positions 3 and 4 on the phenyl ring, and the hydroxyl group at the carboxyl terminus, offers unique reactivity and selectivity in peptide synthesis.The Boc protecting group acts as a safeguard for the amine group present in the phenylalanine residue, preventing unwanted side reactions during the peptide chain assembly. The chlorine substituents provide steric hindrance and electronic effects, influencing the peptide's conformation and interactions with biological targets. Additionally, the hydroxyl group offers versatility for further functionalization or modification to tailor the peptide properties for specific applications.Overall, Boc-D-Phe(3,4-Cl2)-OH serves as a versatile and valuable building block in peptide synthesis, enabling chemists to design and construct diverse peptides with tailored structures, properties, and activities for applications in drug discovery, materials science, and biochemical research.