1150114-78-5 | 2-Chloro-5-formylphenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
5g	97%	in stock	$9.00	$7.00
10g	97%	in stock	$12.00	$9.00

Description

• Catalog Number: AA20069
• Chemical Name: 2-Chloro-5-formylphenylboronic acid
• CAS Number: 1150114-78-5
• Molecular Formula: C7H6BClO3
• Molecular Weight: 184.3847
• MDL Number: MFCD06656269
• SMILES: O=Cc1ccc(c(c1)B(O)O)Cl

Computed Properties

• Complexity: 165
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2

Upstream Synthesis Route

(2-Chloro-5-formylphenyl)boronic acid is a versatile chemical compound widely utilized in organic synthesis. Its primary application lies in the field of cross-coupling reactions, particularly in the Suzuki-Miyaura coupling reaction. This reaction involves the coupling of an aryl or vinyl boronic acid with an organic halide or triflate, mediated by a palladium catalyst.In the context of chemical synthesis, (2-Chloro-5-formylphenyl)boronic acid serves as a valuable building block for the construction of various biaryl compounds, which are essential structural motifs found in many natural products, pharmaceuticals, and materials. By acting as a key component in cross-coupling reactions, this compound enables the formation of complex molecular structures with high efficiency and precision. Its unique reactivity and stability make it an indispensable tool for organic chemists in the creation of diverse chemical compounds with specific functionalities and properties.

Literature

• 2-[4-Chloro-3-(4-ethoxy-benz-yl)phen-yl]-1,3-dithiane.

  Acta crystallographica. Section E, Structure reports online 20100601