1150271-45-6 | Oxindole-7-boronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$50.00	$35.00
1g	95%	in stock	$140.00	$98.00
5g	95%	in stock	$643.00	$450.00
25g	95%	in stock	$2,997.00	$2,098.00

Description

• Catalog Number: AA20176
• Chemical Name: Oxindole-7-boronic acid, pinacol ester
• CAS Number: 1150271-45-6
• Molecular Formula: C14H16BNO3
• Molecular Weight: 257.09274
• MDL Number: MFCD11855966
• SMILES: O=C1N=c2c(=C1)cccc2B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 380
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1

Upstream Synthesis Route

The compound 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one, commonly known as $name$, plays a crucial role in chemical synthesis as a versatile building block. Its unique structure and reactivity make it a valuable tool in the creation of complex organic molecules. In particular, $name$ is utilized in the synthesis of various pharmaceuticals, agrochemicals, and materials.One key application of $name$ is in the formation of carbon-carbon bonds through Suzuki-Miyaura cross-coupling reactions. By incorporating $name$ as a boron-containing coupling partner, chemists can efficiently construct biaryl and heteroaryl structures, which are prevalent motifs in many bioactive compounds. This strategy enables the rapid assembly of diverse molecular architectures with high efficiency and specificity.Furthermore, the presence of the boron moiety in $name$ allows for further functionalization through metal-catalyzed transformations, such as palladium-catalyzed cross-coupling reactions. This feature expands the synthetic utility of $name$, enabling the introduction of additional substituents or elaboration of the indolinone core to access structurally diverse scaffolds.Overall, the strategic incorporation of $name$ in chemical synthesis offers a powerful means to access novel compounds, accelerate drug discovery efforts, and enhance the synthesis of complex molecules with potential applications in various fields of science and technology.