1150561-76-4 | 1-Acetyl-1H-pyrazole-4-boronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$35.00	$25.00
1g	95%	in stock	$45.00	$32.00

Description

• Catalog Number: AA20273
• Chemical Name: 1-Acetyl-1H-pyrazole-4-boronic acid, pinacol ester
• CAS Number: 1150561-76-4
• Molecular Formula: C11H17BN2O3
• Molecular Weight: 236.0753
• MDL Number: MFCD09027064
• SMILES: CC(=O)n1ncc(c1)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 317
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1

Upstream Synthesis Route

1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone is a versatile compound commonly utilized in chemical synthesis as a key building block for the preparation of various organic compounds. With its unique structure and reactivity, this compound serves as an important intermediate in the creation of pharmaceuticals, agrochemicals, and materials.In chemical synthesis, 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone acts as a valuable reagent for Suzuki-Miyaura cross-coupling reactions. This process involves the coupling of an aryl or vinyl halide with an organic boronic acid derivative, leading to the formation of biaryl or bivinyl compounds. The presence of the dioxaborolane moiety in this compound enables efficient and selective cross-coupling reactions, making it an essential tool for building complex molecular structures with high precision.Additionally, the pyrazole group in 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone imparts unique chemical properties, allowing for further derivatization and functionalization of the synthesized molecules. This compound's strategic placement of functional groups facilitates the creation of diverse chemical libraries for drug discovery, materials science, and other research applications.Overall, 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone plays a crucial role in modern organic synthesis, enabling the construction of intricate molecular architectures with enhanced control and efficiency. Its wide-ranging applications make it a valuable asset in the toolbox of synthetic chemists seeking to develop novel compounds with tailored properties and functionalities.