115088-06-7 | N-Succinimidyl 4-(2-pyridyldithio)butanoate

Packsize	Purity	Availability	Price	Discounted Price
100mg	tech grade	in stock	$412.00	$289.00
250mg	tech grade	in stock	$799.00	$559.00

Description

• Catalog Number: AA20369
• Chemical Name: N-Succinimidyl 4-(2-pyridyldithio)butanoate
• CAS Number: 115088-06-7
• Molecular Formula: C13H14N2O4S2
• Molecular Weight: 326.3913
• MDL Number: MFCD20229028
• SMILES: O=C(ON1C(=O)CCC1=O)CCCSSc1ccccn1

Upstream Synthesis Route

SPDB, or N-Succinimidyl 3-(2-pyridyldithio)propionate, is a crucial reagent commonly used in chemical synthesis for the modification and functionalization of biomolecules. This compound is specifically designed to facilitate the conjugation of thiol-containing molecules to primary amines by forming stable disulfide bonds.In chemical synthesis, SPDB plays a key role in various bioconjugation reactions, such as protein labeling, antibody modifications, and peptide synthesis. Its unique structure containing a succinimidyl ester group enables selective and efficient cross-linking of biomolecules, allowing for the creation of complex bioconjugates with enhanced stability and functionality.Furthermore, the pyridyl disulfide moiety of SPDB imparts specific chemical reactivity, making it a valuable tool for site-specific modifications and the construction of advanced bioconjugates. With precise control over the conjugation process, SPDB offers a versatile solution for manipulating biomolecular structures and designing novel bioconjugates for diverse applications in chemistry and biotechnology.