1152-61-0 | Z-Asp-OH

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$16.00	$11.00
5g	98%	in stock	$21.00	$15.00
100g	98%	in stock	$30.00	$21.00

Description

• Catalog Number: AA21071
• Chemical Name: Z-Asp-OH
• CAS Number: 1152-61-0
• Molecular Formula: C12H13NO6
• Molecular Weight: 267.2347
• MDL Number: MFCD00002719
• SMILES: O=C(N[C@H](C(=O)O)CC(=O)O)OCc1ccccc1

Computed Properties

• Complexity: 337
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 7
• XLogP3: 0.6

Upstream Synthesis Route

Z-Asp-OH, also known as Z-aspartic acid, is a versatile compound widely utilized in chemical synthesis. Its application in various organic reactions makes it a valuable tool for chemists in the field.One key application of Z-Asp-OH is as a protecting group for the aspartic acid amino acid residue in peptide synthesis. By selectively protecting the carboxyl group of aspartic acid with the Z group, chemists can prevent undesired side reactions during the peptide assembly process. This protection allows for the efficient and controlled assembly of complex peptides and proteins.Furthermore, Z-Asp-OH can also be used in the synthesis of various pharmaceutical compounds and bioactive molecules. Its compatibility with a wide range of chemical reactions and functional groups makes it a versatile building block for the creation of structurally diverse compounds with potential therapeutic applications.Overall, the utility of Z-Asp-OH in chemical synthesis lies in its ability to serve as a protective group and a versatile building block, enabling the efficient construction of complex molecules with precision and control.

Literature

• A nanosensor for TNT detection based on molecularly imprinted polymers and surface enhanced Raman scattering.

  Sensors (Basel, Switzerland) 20110101

• Inhibition of interleukin-1beta converting enzyme (ICE or caspase 1) by aspartyl acyloxyalkyl ketones and aspartyl amidooxyalkyl ketones.

  Bioorganic & medicinal chemistry letters 20100901

• Chiral ligand exchange potentiometric aspartic acid sensors with polysiloxane films containing a chiral ligand N-carbobenzoxy-aspartic acid.

  Analytical chemistry 20090301

• Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

  Nature chemical biology 20090101

• Peptide synthesis of aspartame precursor using organic-solvent-stable PST-01 protease in monophasic aqueous-organic solvent systems.

  Biotechnology progress 20070101

• Beta-catenin in the fibroproliferative response to acute lung injury.

  American journal of respiratory cell and molecular biology 20060301

• PLGA-(L-Asp-alt-diol)(x)-PLGAs with different contents of pendant amino groups: synthesis and characterization.

  Macromolecular bioscience 20050714

• Synthesis and anticonvulsant evaluation of N-Cbz-alpha-amino-N-alkoxysuccinimides.

  Archives of pharmacal research 20040301

• Induction of apoptosis by dexrazoxane (ICRF-187) through caspases in the absence of c-jun expression and c-Jun NH2-terminal kinase 1 (JNK1) activation in VM-26-resistant CEM cells.

  Biochemical pharmacology 19991015