115520-21-3 | Fmoc-cys(trt)-opfp

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$19.00	$13.00
5g	95%	in stock	$65.00	$46.00
25g	95%	in stock	$231.00	$162.00
100g	95%	in stock	$738.00	$517.00

Description

• Catalog Number: AA20671
• Chemical Name: Fmoc-cys(trt)-opfp
• CAS Number: 115520-21-3
• Molecular Formula: C43H30F5NO4S
• Molecular Weight: 751.7596
• MDL Number: MFCD00065639
• SMILES: O=C(N[C@H](C(=O)Oc1c(F)c(F)c(c(c1F)F)F)CSC(c1ccccc1)(c1ccccc1)c1ccccc1)OCC1c2ccccc2-c2c1cccc2

Upstream Synthesis Route

Fmoc-Cys(Trt)-OPFP is a crucial reagent widely utilized in peptide synthesis due to its unique properties. This compound serves as a versatile building block in chemical reactions, specifically in solid-phase peptide synthesis (SPPS) and bioconjugation strategies.The Fmoc protecting group shields the thiol functionality of cysteine, preventing unwanted side reactions during peptide elongation. Furthermore, the trityl (Trt) protecting group ensures the amino group of cysteine remains free for subsequent reactions, enhancing the selectivity and efficiency of the synthetic process. The OPFP group offers additional protection and can be selectively removed under mild conditions, providing control over peptide deprotection steps.In peptide synthesis, Fmoc-Cys(Trt)-OPFP is often incorporated at specific positions to introduce cysteine residues with precise protection patterns. This allows for the synthesis of complex peptides and peptidomimetics with tailored functionalities and structural motifs. Additionally, the compatibility of Fmoc-Cys(Trt)-OPFP with various coupling and deprotection protocols makes it a valuable tool for the synthesis of diverse peptide sequences and modifications.Overall, the strategic application of Fmoc-Cys(Trt)-OPFP in chemical synthesis enables the efficient and controlled assembly of peptide-based molecules with intricate structures and desired bioactivities.