115761-79-0 | 1-(2,4-difluorophenyl)piperazine

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$16.00	$11.00
5g	98%	in stock	$46.00	$32.00
25g	98%	in stock	$169.00	$118.00
100g	98%	in stock	$510.00	$357.00
500g	98%	in stock	$2,157.00	$1,510.00

Description

• Catalog Number: AA21607
• Chemical Name: 1-(2,4-difluorophenyl)piperazine
• CAS Number: 115761-79-0
• Molecular Formula: C10H12F2N2
• Molecular Weight: 198.2125
• MDL Number: MFCD00082588
• SMILES: Fc1ccc(c(c1)F)N1CCNCC1

Computed Properties

• Complexity: 183
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.6

Upstream Synthesis Route

1-(2,4-Difluorophenyl)piperazine is a versatile compound commonly employed in chemical synthesis as a valuable building block for various pharmaceuticals and organic molecules. Its unique structure, characterized by a piperazine ring attached to a 2,4-difluorophenyl moiety, imparts specific functional properties that make it highly sought-after in the field of medicinal chemistry. This compound serves as a crucial intermediate in the synthesis of a wide range of bioactive compounds, including antipsychotic drugs, antidepressants, and antihistamines. By incorporating 1-(2,4-Difluorophenyl)piperazine into molecular structures, chemists can modulate the pharmacokinetic and pharmacological properties of the final products, enhancing their therapeutic efficacy and reducing potential side effects. Its strategic placement within a molecule can influence factors such as lipophilicity, biological activity, and receptor binding affinity, making it an essential tool for the rational design and optimization of drug candidates. Additionally, the presence of the difluorophenyl group offers opportunities for further functionalization through various synthetic transformations, expanding the scope of potential applications in drug discovery and development.