1158763-56-4 | 5-(2-Fluorophenyl)picolinic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	96%	in stock	$185.00	$130.00
1g	96%	in stock	$448.00	$314.00
5g	96%	in stock	$1,317.00	$922.00
10g	96%	in stock	$2,002.00	$1,402.00
25g	96%	in stock	$3,867.00	$2,707.00

Description

• Catalog Number: AA21854
• Chemical Name: 5-(2-Fluorophenyl)picolinic acid
• CAS Number: 1158763-56-4
• Molecular Formula: C12H8FNO2
• Molecular Weight: 217.1958
• MDL Number: MFCD12406463
• SMILES: Fc1ccccc1c1ccc(nc1)C(=O)O

Computed Properties

• Complexity: 259
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 2.4

Upstream Synthesis Route

5-(2-Fluorophenyl)picolinic acid, also known as 2-Fluoro-5-picolinic acid, is a key component in chemical synthesis processes due to its versatility and unique properties. This compound serves as a valuable building block in the creation of various pharmaceuticals, agrochemicals, and materials. Its fluorine substitution enhances its reactivity and offers specific characteristics that make it particularly useful in the following applications:1. Medicinal Chemistry: 5-(2-Fluorophenyl)picolinic acid is often utilized in medicinal chemistry to synthesize potential drug candidates. The inclusion of the fluorine atom can influence the compound's pharmacokinetic properties, bioavailability, and metabolic stability, making it crucial in drug discovery and development.2. Agrochemical Synthesis: The compound is also employed in the synthesis of agrochemicals, such as herbicides and insecticides. The fluorine substitution can enhance the biological activity and selectivity of these agricultural products, improving their effectiveness in pest control and weed management.3. Material Science: In the field of material science, 5-(2-Fluorophenyl)picolinic acid is used to develop specialized materials with tailored properties. Its incorporation can lead to the creation of functional materials with unique physical and chemical characteristics, making it an essential component in the production of advanced materials.4. Coordination Chemistry: The picolinic acid moiety in this compound also enables coordination with metal ions, allowing for the formation of coordination complexes. This property is valuable in catalysis, nanoparticle synthesis, and other applications where controlled interactions with metal centers are required.5. Chemical Biology: Researchers use 5-(2-Fluorophenyl)picolinic acid in chemical biology studies to probe biological systems and elucidate molecular mechanisms. Its fluorinated structure enables precise labeling and tracking of biomolecules, facilitating the understanding of complex biological processes.In summary, 5-(2-Fluorophenyl)picolinic acid is a versatile compound that finds widespread use in chemical synthesis, contributing to advancements in various fields such as medicinal chemistry, agrochemical development, material science, coordination chemistry, and chemical biology. Its unique properties and reactivity make it a valuable tool for researchers and chemists seeking to design and create novel compounds with specific functions and applications.