1159-54-2 | Tris(4-chlorophenyl)phosphine

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$7.00	$5.00
5g	98%	in stock	$9.00	$7.00
10g	98%	in stock	$11.00	$8.00

Description

• Catalog Number: AA21948
• Chemical Name: Tris(4-chlorophenyl)phosphine
• CAS Number: 1159-54-2
• Molecular Formula: C18H12Cl3P
• Molecular Weight: 365.620641
• MDL Number: MFCD00013639
• SMILES: Clc1ccc(cc1)P(c1ccc(cc1)Cl)c1ccc(cc1)Cl
• NSC Number: 136459

Computed Properties

• Complexity: 275
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 22
• Rotatable Bond Count: 3
• XLogP3: 6.5

Upstream Synthesis Route

Phosphine, tris(4-chlorophenyl)-, also known as tris(4-chlorophenyl)phosphine or PCP3, is a versatile compound widely employed in chemical synthesis. Its unique structure and properties make it a valuable reagent in various reactions.PCP3 is commonly utilized as a ligand in transition metal-catalyzed cross-coupling reactions, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. This compound can effectively coordinate with metals such as palladium, nickel, and copper, enhancing the catalytic activity and selectivity of these processes.In addition to its role as a ligand, PCP3 can also act as a reducing agent in organic transformations. It has been employed in the reduction of various functional groups, such as carbonyls, imines, and nitro groups, under mild reaction conditions. This capability makes it a valuable tool in the synthesis of complex organic molecules.Furthermore, PCP3 has found applications in other key reactions like palladium-catalyzed sp2-sp3 cross-coupling reactions and hydrodehalogenation reactions. Its ability to facilitate these reactions efficiently has made it a valuable tool for synthetic chemists working in the field of organic and organometallic chemistry.

Literature

• cis-Dichloridobis[tris-(4-chloro-phen-yl)phosphane-κP]platinum(II) acetonitrile monosolvate.

  Acta crystallographica. Section E, Structure reports online 20120901

• Bis{[μ-bis-(diphenyl-arsino)methane-1:2κAs:As']nona-carbonyl-1κC,2κC,3κC-[tris-(4-chloro-phen-yl)phosphine-3κP]-triangulo-triruthenium(0)} chloro-form monosolvate.

  Acta crystallographica. Section E, Structure reports online 20100101

• Synthesis of stable C-phosphonate analogues of Neisseria meningitidis group A capsular polysaccharide structures using modified Mitsunobu reaction conditions.

  Organic & biomolecular chemistry 20061221

• Palladium-catalyzed synthesis of 1-alkylphosphonium salts from 1-alkenes.

  Journal of the American Chemical Society 20060111