116-85-8 | 1-Amino-4-hydroxyanthraquinone

Packsize	Purity	Availability	Price	Discounted Price
1g	96%	in stock	$28.00	$20.00
5g	96%	in stock	$90.00	$63.00
25g	96%	in stock	$369.00	$259.00

Description

• Catalog Number: AB71828
• Chemical Name: 1-Amino-4-hydroxyanthraquinone
• CAS Number: 116-85-8
• Molecular Formula: C14H9NO3
• Molecular Weight: 239.2262
• MDL Number: MFCD00001223
• SMILES: Oc1ccc(c2c1C(=O)c1ccccc1C2=O)N
• NSC Number: 1485

Computed Properties

• Complexity: 381
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• XLogP3: 3.4

Upstream Synthesis Route

1-Amino-4-hydroxyanthracene-9,10-dione, also known as Aminoanthraquinone, is a versatile compound widely used in chemical synthesis. It acts as a key intermediate in the production of various organic compounds due to its unique chemical properties and reactivity. One of its primary applications is in the synthesis of vat dyes, which are a class of dyes commonly used in textile industry for their excellent color fastness and light stability. Aminoanthraquinone serves as a crucial building block in the manufacturing process of these dyes, allowing for the creation of a wide range of vibrant and long-lasting colors. Additionally, this compound is utilized in the synthesis of pharmaceuticals, specifically anticancer agents and antioxidants, showcasing its importance in the field of medicinal chemistry. Its ability to undergo diverse chemical reactions makes it a valuable tool for organic chemists seeking to create novel compounds with specific properties.

Literature

• Inhibition of cytochrome p450 enzymes by quinones and anthraquinones.

  Chemical research in toxicology 20120220

• A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ.

  PloS one 20120101

• Estrogenic activity of anthraquinone derivatives: in vitro and in silico studies.

  Chemical research in toxicology 20100816

• Estimation of the ground and the first excited singlet-state dipole moments of 1,4-disubstituted anthraquinone dyes by the solvatochromic method.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100401

• Sensitised near-IR lanthanide luminescence exploiting anthraquinone-derived chromophores: syntheses and spectroscopic properties.

  Dalton transactions (Cambridge, England : 2003) 20091021

• Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening.

  Bioorganic & medicinal chemistry letters 20081015

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Optochemical sensor for an ornidazole assay using 1-amino-4-allyloxyanthraquinone as a fluorescent indicator.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20050801