1160790-26-0 | 2-(1H-Imidazol-1-yl)pyrimidine-5-boronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$46.00	$33.00
250mg	98%	in stock	$56.00	$39.00
1g	98%	in stock	$126.00	$88.00
5g	98%	in stock	$389.00	$273.00
10g	98%	in stock	$775.00	$543.00
25g	98%	in stock	$1,536.00	$1,075.00

Description

• Catalog Number: AA14803
• Chemical Name: 2-(1H-Imidazol-1-yl)pyrimidine-5-boronic acid, pinacol ester
• CAS Number: 1160790-26-0
• Molecular Formula: C13H17BN4O2
• Molecular Weight: 272.1107
• MDL Number: MFCD11878350
• SMILES: CC1(C)OB(OC1(C)C)c1cnc(nc1)n1cncc1

Computed Properties

• Complexity: 342
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2

Upstream Synthesis Route

2-(1H-Imidazol-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine is a versatile compound widely used in chemical synthesis as a key building block. This compound is particularly valuable in the field of organic chemistry due to its unique structure and reactivity.This molecule serves as an important component in the synthesis of various pharmaceuticals, agrochemicals, and advanced materials. Its imidazole and pyrimidine moieties contribute to its ability to participate in a range of crucial reactions, including cross-coupling reactions, functional group transformations, and heterocyclic synthesis.Due to the presence of the boronate ester group, 2-(1H-Imidazol-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine can act as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions. This allows for the efficient construction of biaryl compounds, which are prevalent in many bioactive molecules.Additionally, the imidazole functionality in this compound enables it to participate in various nucleophilic aromatic substitution reactions, opening up avenues for the synthesis of complex heterocyclic compounds. Its compatibility with a wide range of functional groups makes it a valuable tool in the toolbox of synthetic chemists seeking to access diverse chemical space.In summary, the application of 2-(1H-Imidazol-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine in chemical synthesis facilitates the construction of complex molecules with diverse functionalities, making it an indispensable tool for the development of new drugs, agricultural chemicals, and materials.