1162-56-7 | Delta-6-progesterone

Packsize	Purity	Availability	Price	Discounted Price
25mg	98%	in stock	$42.00	$30.00
100mg	98%	in stock	$122.00	$85.00
1g	98%	in stock	$149.00	$105.00
5g	98%	in stock	$596.00	$417.00

Description

• Catalog Number: AA15209
• Chemical Name: Delta-6-progesterone
• CAS Number: 1162-56-7
• Molecular Formula: C21H28O2
• Molecular Weight: 312.44581999999997
• MDL Number: MFCD00199858
• SMILES: O=C1CC[C@]2(C(=C1)C=C[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2C(=O)C)C)C

Computed Properties

• Complexity: 628
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 6
• Heavy Atom Count: 23
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 3.8

Upstream Synthesis Route

Pregna-4,6-diene-3,20-dione, commonly known as pregnadienedione, plays a crucial role in chemical synthesis due to its versatile reactivity and structural properties. This compound serves as a key intermediate in the manufacturing of various important pharmaceuticals and steroids. Its unique structure containing both a ketone group and a conjugated diene system allows for numerous possibilities in organic transformations.In chemical synthesis, pregnadienedione is used as a starting material for the preparation of corticosteroids, such as cortisone and hydrocortisone, which are essential anti-inflammatory medications. Through a series of selective chemical reactions, pregnadienedione can be functionalized to introduce specific functional groups at precise positions on the steroid backbone, enabling the synthesis of a wide range of corticosteroid analogs with tailored pharmacological properties.Additionally, pregnadienedione serves as a precursor in the synthesis of other bioactive compounds, including sex hormones like progesterone and testosterone. By utilizing its carbonyl group and conjugated diene system as reactive sites, chemists can efficiently construct complex molecules with high stereochemical control, facilitating the development of new pharmaceuticals and research chemicals.Overall, the strategic use of pregnadienedione in chemical synthesis highlights its importance as a versatile building block for creating biologically active molecules with diverse applications in the pharmaceutical and biomedical industries.

Literature

• C-7 analogues of progesterone as potent inhibitors of the P-glycoprotein efflux pump.

  Journal of medicinal chemistry 20020117