116574-74-4 | 3-Fluoropyrrolidine

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$203.00	$142.00
1g	95%	in stock	$511.00	$358.00
5g	95%	in stock	$2,004.00	$1,403.00

Description

• Catalog Number: AA16390
• Chemical Name: 3-Fluoropyrrolidine
• CAS Number: 116574-74-4
• Molecular Formula: C4H8FN
• Molecular Weight: 89.1114
• MDL Number: MFCD06738454
• SMILES: FC1CNCC1

Computed Properties

• Complexity: 46.8
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Undefined Atom Stereocenter Count: 1
• XLogP3: 0.3

Upstream Synthesis Route

3-Fluoropyrrolidine is a versatile compound widely employed in chemical synthesis for the preparation of various pharmaceuticals, agrochemicals, and specialty chemicals. As a key building block, 3-Fluoropyrrolidine serves as a valuable intermediate in the synthesis of complex organic molecules. Its unique structure and reactivity make it a valuable tool in the development of new drug candidates and other fine chemicals. In particular, 3-Fluoropyrrolidine has found applications in the synthesis of heterocyclic compounds, peptide analogs, and bioactive molecules. Its incorporation into molecular frameworks imparts desirable physicochemical properties and biological activities, making it a valuable asset in the modern chemical synthesis toolbox.

Literature

• 4-Fluoropyrrolidine-2-carbonyl fluorides: useful synthons and their facile preparation with 4-tert-butyl-2,6-dimethylphenylsulfur trifluoride.

  The Journal of organic chemistry 20110506

• Fluoropyrrolidine amides as dipeptidyl peptidase IV inhibitors.

  Bioorganic & medicinal chemistry letters 20040308