116783-35-8 | Fmoc-thr(galnac(ac)3-alpha-d)-oh

Packsize	Purity	Availability	Price	Discounted Price
5mg	≥98%	in stock	$185.00	$129.00
50mg	98%	in stock	$242.00	$170.00
100mg	98%	in stock	$483.00	$338.00

Description

• Catalog Number: AA16945
• Chemical Name: Fmoc-thr(galnac(ac)3-alpha-d)-oh
• CAS Number: 116783-35-8
• Molecular Formula: C33H38N2O13
• Molecular Weight: 670.6604
• MDL Number: MFCD00171374
• SMILES: CC(=O)OC[C@H]1O[C@H](O[C@@H]([C@@H](C(=O)O)NC(=O)OCC2c3ccccc3c3c2cccc3)C)[C@@H]([C@H]([C@H]1OC(=O)C)OC(=O)C)NC(=O)C

Upstream Synthesis Route

Fmoc-L-Thr(α-D-GalNAc(Ac)3)-OH is a valuable tool in chemical synthesis, particularly in the field of peptide and glycopeptide synthesis. This compound serves as a key building block for the construction of complex peptides and glycopeptides due to its unique structure and reactivity.In peptide synthesis, Fmoc-L-Thr(α-D-GalNAc(Ac)3)-OH can be used as a protected amino acid, where the Fmoc (9-fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amine functionality. This allows for selective deprotection and subsequent coupling reactions to build peptide chains with high efficiency and purity.When it comes to glycopeptide synthesis, the incorporation of the α-D-GalNAc(Ac)3 moiety provides the desired glycosylation pattern, which is crucial for mimicking natural glycoproteins and studying their biological functions. By selectively modifying the threonine residue with this complex sugar unit, researchers can create structurally diverse glycopeptides with tailored properties for various applications in chemical biology and drug discovery.Overall, the application of Fmoc-L-Thr(α-D-GalNAc(Ac)3)-OH in chemical synthesis offers a versatile and strategic approach to the design and assembly of complex peptides and glycopeptides with enhanced functionalities and biological relevance.