117-80-6 | 2,3-Dichloro-1,4-naphthoquinone

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$25.00	$17.00
25g	95%	in stock	$37.00	$26.00
100g	95%	in stock	$89.00	$62.00
500g	95%	in stock	$297.00	$208.00

Description

• Catalog Number: AA17303
• Chemical Name: 2,3-Dichloro-1,4-naphthoquinone
• CAS Number: 117-80-6
• Molecular Formula: C10H6Cl2O2
• Molecular Weight: 229.05944000000002
• MDL Number: MFCD00001677
• SMILES: ClC1C(Cl)C(=O)c2c(C1=O)cccc2
• NSC Number: 537

Computed Properties

• Complexity: 301
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 2
• XLogP3: 3.4

Upstream Synthesis Route

2,3-Dichloro-1,4-naphthoquinone, also known as dichlone, is a versatile compound widely used in chemical synthesis. Its strong electron-withdrawing chlorine substituents make it a valuable reagent in various reactions. One important application of this compound in chemical synthesis is as a key component in the synthesis of biologically active molecules.In organic chemistry, 2,3-dichloro-1,4-naphthoquinone is commonly used as an oxidizing agent in the preparation of quinones and related compounds. It serves as an efficient oxidant in the conversion of various functional groups, such as phenols, anilines, and sulfides, to their corresponding quinone derivatives. This oxidative transformation is crucial in the synthesis of pharmaceuticals, agrochemicals, and natural products.Furthermore, the unique structural features of 2,3-dichloro-1,4-naphthoquinone enable its use in the construction of complex heterocycles. By engaging in diverse cycloaddition reactions, this compound facilitates the formation of fused ring systems with significant biological activities. These heterocyclic frameworks are essential building blocks in medicinal chemistry and drug discovery efforts.Overall, the versatile nature of 2,3-dichloro-1,4-naphthoquinone makes it a valuable tool for chemists engaged in synthetic organic chemistry. Its ability to drive challenging transformations and enable the construction of diverse molecular scaffolds underscores its importance in modern chemical synthesis.

Literature

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