1174020-48-4 | tert-Butyl (3s,4r)-3-fluoro-4-hydroxypyrrolidine-1-carboxylate

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$83.00	$59.00
250mg	95%	in stock	$184.00	$129.00
500mg	95%	in stock	$347.00	$243.00
1g	95%	in stock	$656.00	$459.00
5g	95%	in stock	$2,412.00	$1,688.00
10g	95%	in stock	$4,241.00	$2,969.00

Description

• Catalog Number: AA18244
• Chemical Name: tert-Butyl (3s,4r)-3-fluoro-4-hydroxypyrrolidine-1-carboxylate
• CAS Number: 1174020-48-4
• Molecular Formula: C9H16FNO3
• Molecular Weight: 205.22664319999998
• MDL Number: MFCD23106144
• SMILES: F[C@H]1CN(C[C@H]1O)C(=O)OC(C)(C)C

Computed Properties

• Complexity: 227
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 0.7

Upstream Synthesis Route

In chemical synthesis, (3S,4R)-1-Boc-3-fluoro-4-hydroxypyrrolidine serves as a valuable building block for the creation of diverse and complex organic compounds. This compound's unique structure, characterized by a fluorine substituent and a Boc (tert-butoxycarbonyl) protecting group on the nitrogen atom, lends itself to various synthetic pathways and transformations.One key application of (3S,4R)-1-Boc-3-fluoro-4-hydroxypyrrolidine is its utility in the formation of fluorinated analogs of natural products or biologically active molecules. The introduction of a fluorine atom can impart significant changes in the physicochemical properties and biological activities of the resulting compounds. This compound can be strategically incorporated into the target molecule at specific positions, enabling the synthesis of novel drug candidates or research probes.Additionally, (3S,4R)-1-Boc-3-fluoro-4-hydroxypyrrolidine can participate in stereoselective reactions, taking advantage of its chiral centers to influence the stereochemistry of the final product. This compound's chirality can be leveraged in the construction of complex molecular architectures with high levels of stereocontrol, crucial in pharmaceutical and materials science applications.Furthermore, (3S,4R)-1-Boc-3-fluoro-4-hydroxypyrrolidine can undergo further functional group manipulations, such as deprotection of the Boc group or derivatization of the hydroxyl moiety, expanding its synthetic versatility. Its compatibility with various reaction conditions and transformation methods makes it a versatile tool for organic chemists seeking to access structurally diverse compounds with tailored properties.