118062-05-8 | 2,3,4-Trimethoxyphenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$19.00	$13.00
5g	98%	in stock	$35.00	$25.00
25g	≥98%	in stock	$85.00	$59.00

Description

• Catalog Number: AD60876
• Chemical Name: 2,3,4-Trimethoxyphenylboronic acid
• CAS Number: 118062-05-8
• Molecular Formula: C9H13BO5
• Molecular Weight: 212.0075
• MDL Number: MFCD01318183
• SMILES: COc1ccc(c(c1OC)OC)B(O)O

Computed Properties

• Complexity: 189
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4

Upstream Synthesis Route

(2,3,4-Trimethoxyphenyl)boronic acid, a versatile compound commonly used in chemical synthesis, serves as a key building block in the creation of various organic molecules. As a boronic acid derivative, it plays a crucial role in Suzuki-Miyaura cross-coupling reactions, a widely utilized method in organic synthesis for forming carbon-carbon bonds. This compound's ability to facilitate the coupling of an aromatic boronic acid with an aryl or vinyl halide enables the efficient and selective synthesis of complex organic compounds. Moreover, (2,3,4-Trimethoxyphenyl)boronic acid is instrumental in the production of pharmaceuticals, agrochemicals, and materials science, making it an essential tool for chemists seeking to construct novel and diverse molecular structures.

Literature

• Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization.

  Journal of medicinal chemistry 20101111