1184-85-6 | N-Methyl methanesulfonamide

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$8.00	$5.00
25g	98%	in stock	$10.00	$7.00
100g	98%	in stock	$25.00	$17.00

Description

• Catalog Number: AB77561
• Chemical Name: N-Methyl methanesulfonamide
• CAS Number: 1184-85-6
• Molecular Formula: C2H7NO2S
• Molecular Weight: 109.1475
• MDL Number: MFCD00776277
• SMILES: CNS(=O)(=O)C
• NSC Number: 137909

Computed Properties

• Complexity: 108
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: -0.7

Upstream Synthesis Route

N-Methylmethane sulfonamide, also known as MMSA, is a versatile compound widely used in chemical synthesis. Its primary application lies in its ability to serve as a highly effective and selective methylating reagent in various organic transformations. When utilized in reactions, N-methylmethane sulfonamide can facilitate the transfer of methyl groups to specific substrates with high precision and efficiency, leading to the formation of desired products in a controlled manner.Additionally, N-methylmethane sulfonamide plays a crucial role as a protecting group in organic synthesis. By selectively masking reactive functional groups within complex molecules, MMSA helps to prevent unwanted side reactions and ensures the successful completion of multi-step synthesis processes. This protective function is particularly valuable in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals where precise manipulation of functional groups is essential.Moreover, the unique properties of N-methylmethane sulfonamide make it a valuable tool in the field of medicinal chemistry. Its ability to introduce methyl groups under mild conditions allows researchers to modify the structure of bioactive compounds with precision, leading to the discovery of novel drug candidates and the optimization of existing therapeutic agents.Overall, N-Methylmethane sulfonamide stands out as a versatile and indispensable reagent in chemical synthesis, offering a wide range of applications in the preparation of complex organic molecules with high efficiency and selectivity.

Literature

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  Regulatory toxicology and pharmacology : RTP 20100301

• [In vitro activity of human bone marrow cells after cryopreservation in liquid nitrogen for 21 - 25 years].

  Zhongguo shi yan xue ye xue za zhi 20100201

• Design, synthesis, and evaluation of Leu*Ala hydroxyethylene-based non-peptide beta-secretase (BACE) inhibitors.

  Bioorganic & medicinal chemistry 20060701