1185-57-5 | Ammonium ferric citrate

Packsize	Purity	Availability	Price	Discounted Price
25g	18%	in stock	$25.00	$18.00
100g	18%	in stock	$47.00	$33.00
250g	18%	in stock	$69.00	$48.00
500g	18%	in stock	$105.00	$74.00
1kg	18%	in stock	$126.00	$88.00
5kg	18%	in stock	$469.00	$328.00
10kg	18%	in stock	$869.00	$608.00
25kg	18%	in stock	$2,019.00	$1,413.00

Description

• Catalog Number: AB70694
• Chemical Name: Ammonium ferric citrate
• CAS Number: 1185-57-5
• Molecular Formula: C12H22FeN3O14
• Molecular Weight: 488.1598
• MDL Number: MFCD00013099
• SMILES: [O-]C(=O)C(CC(=O)[O-])(CC(=O)[O-])O.[O-]C(=O)C(CC(=O)[O-])(CC(=O)[O-])O.[Fe+3].[NH4+].[NH4+].[NH4+]

Computed Properties

• Complexity: 233
• Covalently-Bonded Unit Count: 3
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 5

Literature

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  Toxicology 20160715

• Ferric ion could facilitate osteoclast differentiation and bone resorption through the production of reactive oxygen species.

  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20121101

• Iron excess limits HHIPL-2 gene expression and decreases osteoblastic activity in human MG-63 cells.

  Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20121001

• Iron and holotransferrin induce cAMP-dependent differentiation of Schwann cells.

  Neurochemistry international 20121001

• α-Synuclein expression is modulated at the translational level by iron.

  Neuroreport 20120620

• Iron overload inhibits calcification and differentiation of ATDC5 cells.

  Journal of biochemistry 20120101

• Efficiency of ferritin as an MRI reporter gene in NPC cells is enhanced by iron supplementation.

  Journal of biomedicine & biotechnology 20120101

• Ferritin heavy chain-mediated iron homoeostasis regulates expression of IL-10 in Chlamydia trachomatis-infected HeLa cells.

  Cell biology international 20110801

• Increased cellular iron levels affect matrix metalloproteinase expression and phagocytosis in activated microglia.

  Neuroscience letters 20110801

• HFE polymorphisms affect cellular glutamate regulation.

  Neurobiology of aging 20110601

• Expression and iron-dependent regulation of succinate receptor GPR91 in retinal pigment epithelium.

  Investigative ophthalmology & visual science 20110501

• Serum hepcidin and macrophage iron correlate with MCP-1 release and vascular damage in patients with metabolic syndrome alterations.

  Arteriosclerosis, thrombosis, and vascular biology 20110301

• Redox control of iron regulatory protein 2 stability.

  FEBS letters 20110218

• Iron overload triggers redox-sensitive signals in human IMR-32 neuroblastoma cells.

  Neurotoxicology 20110101

• Lysosomal proteolysis is the primary degradation pathway for cytosolic ferritin and cytosolic ferritin degradation is necessary for iron exit.

  Antioxidants & redox signaling 20101001

• Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter.

  Haematologica 20100801

• Effects of iron chelators, iron salts, and iron oxide nanoparticles on the proliferation and the iron content of oligodendroglial OLN-93 cells.

  Neurochemical research 20100801

• Prospective comparative study of negative oral contrast agents for magnetic resonance cholangiopancreatography.

  Japanese journal of radiology 20100201

• Paradoxical role of prion protein aggregates in redox-iron induced toxicity.

  PloS one 20100101

• Defining juxtapapillary diverticulum with 3D segmented trueFISP MRCP: comparison with conventional MRCP sequences with an oral negative contrast agent.

  Japanese journal of radiology 20091201

• Curcumin reduces the toxic effects of iron loading in rat liver epithelial cells.

  Liver international : official journal of the International Association for the Study of the Liver 20090101

• Influence of HFE variants and cellular iron on monocyte chemoattractant protein-1.

  Journal of neuroinflammation 20090101

• Gentian violet and ferric ammonium citrate disrupt Pseudomonas aeruginosa biofilms.

  The Laryngoscope 20081101

• Iron increases MMP-9 expression through activation of AP-1 via ERK/Akt pathway in human head and neck squamous carcinoma cells.

  Oral oncology 20080601

• [Elimination of bowel fluid artifact on abdominal DWI using oral contrast agent ferric ammonium citrate].

  Nihon Hoshasen Gijutsu Gakkai zasshi 20080520

• Iron-chelator complexes as iron sources for early developing human erythroid precursors.

  Translational research : the journal of laboratory and clinical medicine 20080201

• Neoplastic transformation of rat liver epithelial cells is enhanced by non-transferrin-bound iron.

  BMC gastroenterology 20080101

• Divalent metal transporter 1 up-regulation is involved in the 6-hydroxydopamine-induced ferrous iron influx.

  Journal of neuroscience research 20071101

• [Oral ferric ammonium citrate solution in MRCP for diagnosing low-level obstructive jaundice].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20070401

• Apoptosis induced by crocidolite asbestos in human lung epithelial cells involves inactivation of Akt and MAPK pathways.

  Apoptosis : an international journal on programmed cell death 20070201

• Glutathione peroxidase 1 and glutathione are required to protect mouse astrocytes from iron-mediated hydrogen peroxide toxicity.

  Journal of neuroscience research 20060815

• Iron regulatory protein-independent regulation of ferritin synthesis by nitrogen monoxide.

  The FEBS journal 20060801

• The influence of gallium and other metal ions on the uptake of non-transferrin-bound iron by rat hepatocytes.

  Biochimie 20060601

• Enhanced contrast of bacteriophage plaques in Salmonella with ferric ammonium citrate and sodium thiosulfate (FACST) and tetrazolium red (TZR).

  Journal of microbiological methods 20060501

• Characterization of anti-apoptotic action of TCDD as a defensive cellular stress response reaction against the cell damaging action of ultra-violet irradiation in an immortalized normal human mammary epithelial cell line, MCF10A.

  Toxicology 20060116

• Iron loading inhibits ferroportin1 expression in PC12 cells.

  Neurochemistry international 20051201

• Divalent metal transporter-1 decreases metal-related injury in the lung.

  American journal of physiology. Lung cellular and molecular physiology 20050901

• Increased iron-induced oxidative stress and toxicity in scrapie-infected neuroblastoma cells.

  Neuroscience letters 20050715

• Iron salts perturb biofilm formation and disrupt existing biofilms of Pseudomonas aeruginosa.

  Chemistry & biology 20050701

• Effects of extracellular iron concentration on calcium absorption and relationship between Ca2+ and cell apoptosis in Caco-2 cells.

  World journal of gastroenterology 20050521

• Iron absorption by human subjects from different iron fortification compounds added to Thai fish sauce.

  European journal of clinical nutrition 20050501

• Changed iron regulation in scrapie-infected neuroblastoma cells.

  Brain research. Molecular brain research 20050218

• The potential of encapsulated iron compounds in food fortification: a review.

  International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20041101

• Modulation of iron on mitochondrial aconitase expression in human prostatic carcinoma cells.

  Molecular and cellular biochemistry 20041001

• Pharmacological but not physiological concentrations of melatonin reduce iron-induced neuronal death in rat cerebral cortex.

  Neuroscience letters 20040527

• Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin.

  Blood 20040315

• Iron accumulation, iron-mediated toxicity and altered levels of ferritin and transferrin receptor in cultured astrocytes during incubation with ferric ammonium citrate.

  Journal of neurochemistry 20040301

• Expression of the SLC11A1 (NRAMP1) 5'-(GT)n repeat: opposite effect in the presence of -237C-->T.

  Blood cells, molecules & diseases 20040101

• Human Abeta1-42 reduces iron-induced toxicity in rat cerebral cortex.

  Journal of neuroscience research 20030801

• [Effect of iron on vasoconstriction in the isolated rat aorta].

  Sheng li xue bao : [Acta physiologica Sinica] 20030625

• [Modulation of iron on the vasodilating effect of interleukin-2 in the isolated aortic ring].

  Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20030601

• Relationships and distinctions in iron-regulatory networks responding to interrelated signals.

  Blood 20030501

• Iron uptake and Nramp2/DMT1/DCT1 in human bronchial epithelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20020501

• Acquisition, storage and release of iron by cultured human hepatoma cells.

  Journal of hepatology 20020101

• Numerous proteins in Mammalian cells are prone to iron-dependent oxidation and proteasomal degradation.

  Developmental neuroscience 20020101

• Influence of interactions between temperature, ferric ammonium citrate and glycine betaine on the growth of Listeria monocytogenes in a defined medium.

  Letters in applied microbiology 20020101

• Iron prevents ferritin turnover in hepatic cells.

  The Journal of biological chemistry 20011228

• Absorption of unlabeled reduced iron of small particle size from a commercial source. A method to predict absorption of unlabeled iron compounds in humans.

  Archivos latinoamericanos de nutricion 20010901

• Quantitative analysis of cell death and ferritin expression in response to cortical iron: implications for hypoxia-ischemia and stroke.

  Brain research 20010713

• Increased release of arachidonic acid and eicosanoids in iron-overloaded cardiomyocytes.

  Circulation 20010515

• Iron and gallium increase iron uptake from transferrin by human melanoma cells: further examination of the ferric ammonium citrate-activated iron uptake process.

  Biochimica et biophysica acta 20010430

• Interferon-gamma and lipopolysaccharide regulate the expression of Nramp2 and increase the uptake of iron from low relative molecular mass complexes by macrophages.

  European journal of biochemistry 20001101