1186403-17-7 | 3-Bromo-5-chlorophenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$6.00	$4.00
1g	95%	in stock	$7.00	$5.00
5g	95%	in stock	$11.00	$8.00
25g	95%	in stock	$46.00	$33.00

Description

• Catalog Number: AB50017
• Chemical Name: 3-Bromo-5-chlorophenylboronic acid
• CAS Number: 1186403-17-7
• Molecular Formula: C6H5BBrClO2
• Molecular Weight: 235.2707
• MDL Number: MFCD13189469
• SMILES: Clc1cc(Br)cc(c1)B(O)O

Computed Properties

• Complexity: 136
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1

Upstream Synthesis Route

(3-Bromo-5-chlorophenyl)boronic acid is a versatile reagent commonly used in organic and medicinal chemistry. This compound plays a crucial role in chemical synthesis as a key building block for creating complex organic molecules. Its unique structure makes it a valuable tool for researchers and chemists looking to develop new pharmaceuticals, agrochemicals, and materials.One prominent application of (3-Bromo-5-chlorophenyl)boronic acid is in Suzuki-Miyaura cross-coupling reactions. In this widely used method, the boronic acid moiety of the compound undergoes a palladium-catalyzed cross-coupling with an organic halide or pseudohalide, leading to the formation of a new carbon-carbon bond. This process enables the efficient construction of biaryl and heteroaryl compounds, which are essential structural motifs in many biologically active molecules.Additionally, (3-Bromo-5-chlorophenyl)boronic acid can be incorporated into various chemical transformations such as Heck reactions, hydrogenation reactions, and Buchwald-Hartwig amination. By leveraging the reactivity of the boronic acid functionality, chemists can access a diverse array of substituted aryl compounds with tailored properties and functionalities.Overall, (3-Bromo-5-chlorophenyl)boronic acid serves as a valuable tool in the toolkit of synthetic chemists, enabling the efficient and precise construction of complex organic molecules with applications across diverse fields of chemistry and biomedicine.