1187-11-7 | Acetylmalononitrile

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$90.00	$63.00
5g	98%	in stock	$203.00	$142.00
10g	98%	in stock	$299.00	$209.00
25g	98%	in stock	$573.00	$402.00

Description

• Catalog Number: AB70438
• Chemical Name: Acetylmalononitrile
• CAS Number: 1187-11-7
• Molecular Formula: C5H4N2O
• Molecular Weight: 108.0981
• MDL Number: MFCD00129155
• SMILES: N#CC(C(=O)C)C#N

Upstream Synthesis Route

Acetylmalononitrile plays a key role in various chemical synthesis processes as a versatile building block. With its unique molecular structure, it serves as a precursor in the synthesis of diverse organic compounds. One of the primary applications of acetylmalononitrile is in the formation of β-diketones through the Knoevenagel condensation reaction. This reaction involves the condensation of acetylmalononitrile with aldehydes or ketones in the presence of a base catalyst, leading to the formation of β-diketones with high regioselectivity. Furthermore, acetylmalononitrile can be utilized in the synthesis of polyfunctional compounds such as α-cyanoacrylates, which are widely used in adhesive formulations. By reacting acetylmalononitrile with appropriate reagents, α-cyanoacrylates can be obtained through a series of chemical transformations. Moreover, acetylmalononitrile is a valuable intermediate in the preparation of pharmaceuticals, agrochemicals, and fine chemicals. Its ability to undergo various reactions including nucleophilic additions, condensations, and substitutions makes it a versatile compound for building complex molecular structures. Overall, the strategic importance of acetylmalononitrile in chemical synthesis lies in its capability to serve as a versatile and efficient starting material for the construction of a wide range of organic molecules with diverse applications.