1187385-96-1 | 5-Bromo-2-morpholino-4-picoline

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$36.00	$25.00
1g	98%	in stock	$82.00	$57.00
5g	98%	in stock	$263.00	$184.00
25g	98%	in stock	$760.00	$532.00

Description

• Catalog Number: AD74260
• Chemical Name: 5-Bromo-2-morpholino-4-picoline
• CAS Number: 1187385-96-1
• Molecular Formula: C10H13BrN2O
• Molecular Weight: 257.127
• MDL Number: MFCD12546513
• SMILES: Cc1cc(ncc1Br)N1CCOCC1

Computed Properties

• Complexity: 185
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• XLogP3: 2

Upstream Synthesis Route

4-(5-Bromo-4-methylpyridin-2-yl)morpholine, also known as $name$, serves as a versatile building block in chemical synthesis. This compound plays a crucial role as a key intermediate in the preparation of various pharmaceuticals, agrochemicals, and fine chemicals. Its unique structure confers it with a range of reactive sites that enable it to participate in a variety of chemical reactions, making it a valuable tool for organic chemists and researchers.One of the primary applications of 4-(5-Bromo-4-methylpyridin-2-yl)morpholine is in the synthesis of heterocyclic compounds. By incorporating this moiety into the structure of target molecules, chemists can modulate the properties and biological activities of the final products. Additionally, the morpholine ring in this compound can serve as a masked amine functionality, allowing for controlled release of a free amine group under specific reaction conditions. This feature proves particularly useful in the design and synthesis of bioactive compounds and drug candidates.Furthermore, 4-(5-Bromo-4-methylpyridin-2-yl)morpholine can be utilized as a nucleophilic reactant in various coupling reactions, such as Suzuki-Miyaura cross-coupling, Buchwald-Hartwig amination, and Heck coupling. These transformations enable the introduction of diverse functional groups and substituents onto the pyridine and morpholine rings, expanding the chemical space accessible for synthetic exploration.Overall, the strategic incorporation of 4-(5-Bromo-4-methylpyridin-2-yl)morpholine in chemical synthesis facilitates the construction of complex molecular architectures with tailored properties, making it a valuable asset in the toolbox of synthetic chemists.