1190129-77-1 | 5-Chloro-2-fluorophenylboronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
1g	96%	in stock	$10.00	$7.00
5g	96%	in stock	$46.00	$33.00
100g	96%	in stock	$712.00	$498.00

Description

• Catalog Number: AA32258
• Chemical Name: 5-Chloro-2-fluorophenylboronic acid, pinacol ester
• CAS Number: 1190129-77-1
• Molecular Formula: C12H15BClFO2
• Molecular Weight: 256.5087
• MDL Number: MFCD16036133
• SMILES: CC1(C)OB(OC1(C)C)c1cc(Cl)ccc1F

Computed Properties

• Complexity: 282
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1

Upstream Synthesis Route

2-(5-Chloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a versatile compound commonly utilized in chemical synthesis as a key building block for creating various organic molecules. Its unique structure provides a valuable platform for introducing specific functional groups and substituents into the desired target molecules.This compound is particularly valuable in Suzuki-Miyaura cross-coupling reactions, where it acts as a boron-containing coupling partner to form carbon-carbon bonds. The presence of both chloro and fluoro substituents on the phenyl ring of the dioxaborolane moiety imparts reactivity and selectivity to the coupling process, allowing for precise control over the synthesis of complex organic compounds.Additionally, the tetramethyl substitution pattern on the boron atom enhances the stability and compatibility of this compound in various reaction conditions, making it a popular choice for chemists seeking efficient and reliable methods for constructing diverse chemical structures. Overall, the application of 2-(5-Chloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane in chemical synthesis enables researchers to access new molecules and materials with tailored properties and functionalities.