119062-05-4 | Fmoc-L-Asp-OH

Packsize	Purity	Availability	Price	Discounted Price
25g	98%	in stock	$13.00	$9.00

Description

• Catalog Number: AA23290
• Chemical Name: Fmoc-L-Asp-OH
• CAS Number: 119062-05-4
• Molecular Formula: C19H17NO6
• Molecular Weight: 355.3414
• MDL Number: MFCD00237654
• SMILES: OC(=O)C[C@@H](C(=O)O)NC(=O)OCC1c2ccccc2-c2c1cccc2

Computed Properties

• Complexity: 528
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 26
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 7
• XLogP3: 2.2

Upstream Synthesis Route

Fmoc-Asp-OH is a valuable building block widely used in chemical synthesis for the production of peptides and proteins. As a derivative of aspartic acid, Fmoc-Asp-OH plays a crucial role in solid-phase peptide synthesis (SPPS) and other organic reactions. It serves as a protected form of aspartic acid, allowing for selective deprotection under mild conditions to enable the stepwise assembly of peptide chains.In peptide synthesis, Fmoc-Asp-OH is utilized as a key component for the incorporation of aspartic acid into the growing peptide chain. The Fmoc (9-fluorenylmethyloxycarbonyl) group functions as a temporary protecting group, shielding the amine group of aspartic acid from unwanted reactions during the peptide elongation process. Through successive deprotection and coupling steps, Fmoc-Asp-OH facilitates the controlled assembly of complex peptide sequences with high purity and efficiency.Moreover, Fmoc-Asp-OH offers versatility in chemical modifications and functional group manipulations, making it indispensable in the synthesis of custom peptides for research, pharmaceutical development, and biotechnological applications. Its compatibility with solid-phase synthesis methods streamlines the production of peptide libraries, mimetics, and bioconjugates, expanding the scope of peptide-based research and drug discovery efforts.Overall, Fmoc-Asp-OH stands as a fundamental component in the toolbox of synthetic chemists, enabling the construction of precise peptide structures with tailored properties and functionalities for a diverse range of scientific and industrial purposes.