1191064-81-9 | Fmoc-N-amido-PEG9-acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$43.00	$30.00
1g	97%	in stock	$165.00	$115.00
5g	97%	in stock	$760.00	$532.00
10g	97%	in stock	$1,319.00	$923.00

Description

• Catalog Number: AE18318
• Chemical Name: Fmoc-N-amido-PEG9-acid
• CAS Number: 1191064-81-9
• Molecular Formula: C36H53NO13
• Molecular Weight: 707.8049199999999
• MDL Number: MFCD28385470
• SMILES: OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2c1cccc2

Computed Properties

• Complexity: 831
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 50
• Hydrogen Bond Acceptor Count: 13
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 33
• XLogP3: 1.2

Upstream Synthesis Route

Fmoc-NH-PEG9-CH2CH2COOH, a key intermediate in chemical synthesis, plays a crucial role in bioconjugation and peptide synthesis. This compound, with its Fmoc-protected amine group and extended polyethylene glycol (PEG) spacer, is commonly used in the fabrication of bioactive molecules and materials.Its application lies in the selective modification of biomolecules, where the Fmoc group acts as a temporary protecting group that can be easily removed under mild conditions to expose the primary amine for further functionalization. The PEG spacer, with its flexible and hydrophilic nature, helps to improve the solubility, stability, and bioavailability of the final conjugates.In peptide synthesis, Fmoc-NH-PEG9-CH2CH2COOH can be employed as a building block to introduce a spacer arm between the peptide sequence and other moieties, facilitating the development of peptide mimics, drug conjugates, and peptide-drug hybrids. This compound's versatility and compatibility with various bioconjugation strategies make it an essential component in the realm of chemical synthesis for diverse applications in pharmaceuticals, diagnostics, and materials science.