1192-07-0 | Isoxazolidin-3-one

Packsize	Purity	Availability	Price	Discounted Price
50mg	98%	in stock	$80.00	$56.00
100mg	98%	in stock	$118.00	$83.00
250mg	98%	in stock	$169.00	$119.00
500mg	98%	in stock	$267.00	$187.00

Description

• Catalog Number: AA23561
• Chemical Name: Isoxazolidin-3-one
• CAS Number: 1192-07-0
• Molecular Formula: C3H5NO2
• Molecular Weight: 87.0773
• MDL Number: MFCD11878032
• SMILES: C1CONC1=O

Computed Properties

• Complexity: 71.2
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: -0.7

Upstream Synthesis Route

Isoxazolidin-3-one, a versatile compound widely utilized in chemical synthesis, boasts a myriad of applications in the field of organic chemistry. This unique five-membered heterocycle serves as a key building block in the construction of complex organic molecules due to its ability to participate in a variety of functional group transformations.In organic synthesis, Isoxazolidin-3-one can serve as a valuable intermediate in the preparation of various pharmaceuticals, agrochemicals, and natural products. Its distinct structural features and reactivity enable the formation of diverse chemical bonds and functional groups through a range of synthetic methodologies. Additionally, its presence in the molecular framework of biologically active compounds underscores its importance in drug discovery and development efforts.The synthetic utility of Isoxazolidin-3-one extends to the construction of heterocyclic frameworks and the synthesis of chiral compounds, highlighting its versatility in the design and assembly of complex molecular architectures. Moreover, its compatibility with a broad array of functional groups makes it an indispensable tool for chemists seeking to access structurally diverse compounds for various applications in medicinal chemistry, materials science, and beyond.Overall, the widespread applicability of Isoxazolidin-3-one in chemical synthesis underscores its significance as a valuable building block for the creation of novel molecules with diverse functionalities and potential biological activities.

Literature

• A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity.

  Journal of medicinal chemistry 20101111

• Differential oxidative metabolism and 5-ketoclomazone accumulation are involved in Echinochloa phyllopogon resistance to clomazone.

  Plant physiology 20100501

• Three siderophores from one bacterial enzymatic assembly line.

  Journal of the American Chemical Society 20090415

• Isolation and structure elucidation of parnafungins C and D, isoxazolidinone-containing antifungal natural products.

  Bioorganic & medicinal chemistry letters 20090215

• A latent oxazoline electrophile for N-O-C bond formation in pseudomonine biosynthesis.

  Journal of the American Chemical Society 20080917

• Isolation and structure elucidation of parnafungins, antifungal natural products that inhibit mRNA polyadenylation.

  Journal of the American Chemical Society 20080604

• Synthesis and absolute configuration assignment of 5-amino-1,3,5-triphenyl-pentane-1,3-diol stereoisomers.

  Chirality 20050101