1192491-61-4 | Avibactam sodium

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$6.00	$4.00
5mg	98%	in stock	$7.00	$5.00
10mg	98%	in stock	$9.00	$6.00
100mg	98%	in stock	$14.00	$10.00
250mg	98%	in stock	$18.00	$13.00
1g	98%	in stock	$34.00	$24.00
5g	98%	in stock	$138.00	$97.00
25g	98%	in stock	$482.00	$338.00

Description

• Catalog Number: AA23694
• Chemical Name: Avibactam sodium
• CAS Number: 1192491-61-4
• Molecular Formula: C7H10N3NaO6S
• Molecular Weight: 287.2256
• MDL Number: MFCD29472268
• SMILES: NC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OS(=O)(=O)[O-].[Na+]

Computed Properties

• Complexity: 462
• Covalently-Bonded Unit Count: 2
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3

Literature

• Role of the Outer Membrane and Porins in Susceptibility of β-Lactamase-Producing Enterobacteriaceae to Ceftazidime-Avibactam.

  Antimicrobial agents and chemotherapy 20160301

• Kinetics of avibactam inhibition against Class A, C, and D β-lactamases.

  The Journal of biological chemistry 20130927

• Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor.

  Proceedings of the National Academy of Sciences of the United States of America 20120717

• Anti-anaerobic activity of a new β-lactamase inhibitor NXL104 in combination with β-lactams and metronidazole.

  International journal of antimicrobial agents 20120601

• In vitro activity of avibactam (NXL104) in combination with β-lactams against Gram-negative bacteria, including OXA-48 β-lactamase-producing Klebsiella pneumoniae.

  International journal of antimicrobial agents 20120101

• New Delhi metallo-β-lactamase (NDM-1): an update.

  Journal of chemotherapy (Florence, Italy) 20111001

• In vitro activity of ceftazidime+NXL104 against Pseudomonas aeruginosa and other non-fermenters.

  The Journal of antimicrobial chemotherapy 20101101

• In vitro activity of the {beta}-lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases.

  The Journal of antimicrobial chemotherapy 20090801